NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|26345448|dbj|BAC36375|]
View 

unnamed protein product, partial [Mus musculus]

Protein Classification

glycoside hydrolase family 35 protein( domain architecture ID 10472897)

glycoside hydrolase family 35 protein similar to Xanthomonas phaseoli beta-galactosidase that catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides

CAZY:  GH35
EC:  3.2.1.-
Gene Ontology:  GO:0004565|GO:0005975
SCOP:  4003303

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Glyco_hydro_35 pfam01301
Glycosyl hydrolases family 35;
41-355 2.08e-179

Glycosyl hydrolases family 35;


:

Pssm-ID: 396048 [Multi-domain]  Cd Length: 316  Bit Score: 512.57  E-value: 2.08e-179
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448    41 RFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVI 120
Cdd:pfam01301   1 SFLIDGKRFRLISGSIHYFRIPPEMWPDRLQKAKALGLNAIETYVFWNLHEPEPGQYDFSGILDLVKFIKLAQEAGLYVI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   121 LRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYfACDYDY 200
Cdd:pfam01301  81 LRPGPYICAEWDFGGLPAWLLTVPGIRLRTSDPPFLEAVERYLTALLPKMKPLQATNGGPIIMVQVENEYGSY-GVDKAY 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   201 LRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQD--LYATVDFGTGNNITQAFLVQRKFEPKGPLINSEFYTGWLDHW 278
Cdd:pfam01301 160 LRALRKAYKEWGADMALLFTTDGPWGMCLQCGDLPGpdIYATNGFGCGANPPSNFKLLRPFSPNKPLMWSEFWTGWFDHW 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 26345448   279 GKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANTPYePQPTSYDYDAPLSEAGDLTKKYFALREVI 355
Cdd:pfam01301 240 GGPHAIRPAEDIAFEVARFLAKNSSVNLYMFHGGTNFGFTNGANFYG-PQTTSYDYDAPIDEAGDPTPKYGHLKDLI 315
 
Name Accession Description Interval E-value
Glyco_hydro_35 pfam01301
Glycosyl hydrolases family 35;
41-355 2.08e-179

Glycosyl hydrolases family 35;


Pssm-ID: 396048 [Multi-domain]  Cd Length: 316  Bit Score: 512.57  E-value: 2.08e-179
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448    41 RFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVI 120
Cdd:pfam01301   1 SFLIDGKRFRLISGSIHYFRIPPEMWPDRLQKAKALGLNAIETYVFWNLHEPEPGQYDFSGILDLVKFIKLAQEAGLYVI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   121 LRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYfACDYDY 200
Cdd:pfam01301  81 LRPGPYICAEWDFGGLPAWLLTVPGIRLRTSDPPFLEAVERYLTALLPKMKPLQATNGGPIIMVQVENEYGSY-GVDKAY 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   201 LRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQD--LYATVDFGTGNNITQAFLVQRKFEPKGPLINSEFYTGWLDHW 278
Cdd:pfam01301 160 LRALRKAYKEWGADMALLFTTDGPWGMCLQCGDLPGpdIYATNGFGCGANPPSNFKLLRPFSPNKPLMWSEFWTGWFDHW 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 26345448   279 GKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANTPYePQPTSYDYDAPLSEAGDLTKKYFALREVI 355
Cdd:pfam01301 240 GGPHAIRPAEDIAFEVARFLAKNSSVNLYMFHGGTNFGFTNGANFYG-PQTTSYDYDAPIDEAGDPTPKYGHLKDLI 315
GanA COG1874
Beta-galactosidase GanA [Carbohydrate transport and metabolism];
41-491 3.24e-55

Beta-galactosidase GanA [Carbohydrate transport and metabolism];


Pssm-ID: 441478 [Multi-domain]  Cd Length: 609  Bit Score: 199.00  E-value: 3.24e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  41 RFLKDgQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQM-YVPWNFHEPQPGQYEFSGdrdVEHFIQLAHELGLLV 119
Cdd:COG1874   2 TFLLD-KPFLILGGDYHPERWPPEVWAEDIRLMKAAGLNTVRIgYFAWNLHEPEEGVFDFDW---LDRFIDLLHEAGLKV 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 120 ILRPGPYIcaewdmggLPAWLLEKQSIVLR-----------------SSDPDYLVAVDKWLAVLLPKmkpllYQNGGPII 182
Cdd:COG1874  78 ILRTPTAA--------PPAWLLKKYPEILPvdadgrrrgfgsrrhycPSSPVYREAARRIVRALAER-----YGDHPAVI 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 183 TVQVENEYGSYFACDYDYLRF---LVHRF-----------------RYHLGNDVIL------------------FTTDGA 224
Cdd:COG1874 145 MWQVDNEYGSYDYCDACAAAFrdwLRERYgtldalneawgtafwsqRYTDWDEIEPprltpttanpslrldfrrFSSDQV 224
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 225 SE--KMLK----------------------------CGTLqDLYATVDFGTGNN---ITQAF--LVQRKFEPKGPLINSE 269
Cdd:COG1874 225 LEylRAQRdilreagpdvpvttnfmgpfpgldywklARDL-DVVSWDNYPDGSAadpDEIAFahDLMRGLKGGGPFMVME 303
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 270 FYTGWLdHWGKPHSTVKTKTLATSLYNLLARGAN-VNLYMfiggtnfaywngantpYEPQP--TSYDYDAPLSEAGDLTK 346
Cdd:COG1874 304 QWPGWV-NWGPYNPAKRPGQLRLWSLQALAHGADgVNYFQ----------------WRPSRggTEYDHDAPLDHAGRPTR 366
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 347 KYFALREVIQMFKEVPEgpIPPSTPKfayGKVALrkfktVAEALGILcpngpvksLYPLTFTQVKQYFGYV-----LYRT 421
Cdd:COG1874 367 KFREVRELGAELARLPE--VPGSRVT---ARVAL-----LFDWESWW--------ALEIQSPPLGQDLGYVdlvraLYRA 428
                       490       500       510       520       530       540       550
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 26345448 422 TLpqdcsnpkpifsspfngvrdRAYVSVDGVPQGI-LDRN---LMTALNIRGKAGAT-LDILVENMGRVNYGRFI 491
Cdd:COG1874 429 LR--------------------RAGVTVDIVPPFAdLSGYkllVAPALYLVSDALAErLLAYVENGGRVNYGPRS 483
PLN03059 PLN03059
beta-galactosidase; Provisional
28-359 4.56e-47

beta-galactosidase; Provisional


Pssm-ID: 166698 [Multi-domain]  Cd Length: 840  Bit Score: 178.66  E-value: 4.56e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   28 VTQRTFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEH 107
Cdd:PLN03059  23 VSHGSASVSYDHRAFIINGQRRILISGSIHYPRSTPEMWPDLIQKAKDGGLDVIQTYVFWNGHEPSPGNYYFEDRYDLVK 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  108 FIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKP--LLYQNGGPIITVQ 185
Cdd:PLN03059 103 FIKVVQAAGLYVHLRIGPYICAEWNFGGFPVWLKYVPGIEFRTDNGPFKAAMQKFTEKIVDMMKSekLFEPQGGPIILSQ 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  186 VENEYGSyfacdydylrflvhrFRYHLGNDVILFTTdGASEKMLKCGT-------LQDLYATVDFGTGNNI-TQAFLVQR 257
Cdd:PLN03059 183 IENEYGP---------------VEWEIGAPGKAYTK-WAADMAVKLGTgvpwvmcKQEDAPDPVIDTCNGFyCENFKPNK 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  258 KFEPKgplINSEFYTGWLDHWGKPHSTVKTKTLATSLYNLLA-RGANVNLYMFIGGTNFAYWNGAntPYepQPTSYDYDA 336
Cdd:PLN03059 247 DYKPK---MWTEAWTGWYTEFGGAVPNRPAEDLAFSVARFIQnGGSFINYYMYHGGTNFGRTAGG--PF--IATSYDYDA 319
                        330       340
                 ....*....|....*....|....*
gi 26345448  337 PLSEAGdLTK--KYFALREVIQMFK 359
Cdd:PLN03059 320 PLDEYG-LPRepKWGHLRDLHKAIK 343
 
Name Accession Description Interval E-value
Glyco_hydro_35 pfam01301
Glycosyl hydrolases family 35;
41-355 2.08e-179

Glycosyl hydrolases family 35;


Pssm-ID: 396048 [Multi-domain]  Cd Length: 316  Bit Score: 512.57  E-value: 2.08e-179
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448    41 RFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVI 120
Cdd:pfam01301   1 SFLIDGKRFRLISGSIHYFRIPPEMWPDRLQKAKALGLNAIETYVFWNLHEPEPGQYDFSGILDLVKFIKLAQEAGLYVI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   121 LRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYfACDYDY 200
Cdd:pfam01301  81 LRPGPYICAEWDFGGLPAWLLTVPGIRLRTSDPPFLEAVERYLTALLPKMKPLQATNGGPIIMVQVENEYGSY-GVDKAY 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   201 LRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQD--LYATVDFGTGNNITQAFLVQRKFEPKGPLINSEFYTGWLDHW 278
Cdd:pfam01301 160 LRALRKAYKEWGADMALLFTTDGPWGMCLQCGDLPGpdIYATNGFGCGANPPSNFKLLRPFSPNKPLMWSEFWTGWFDHW 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 26345448   279 GKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANTPYePQPTSYDYDAPLSEAGDLTKKYFALREVI 355
Cdd:pfam01301 240 GGPHAIRPAEDIAFEVARFLAKNSSVNLYMFHGGTNFGFTNGANFYG-PQTTSYDYDAPIDEAGDPTPKYGHLKDLI 315
GanA COG1874
Beta-galactosidase GanA [Carbohydrate transport and metabolism];
41-491 3.24e-55

Beta-galactosidase GanA [Carbohydrate transport and metabolism];


Pssm-ID: 441478 [Multi-domain]  Cd Length: 609  Bit Score: 199.00  E-value: 3.24e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  41 RFLKDgQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQM-YVPWNFHEPQPGQYEFSGdrdVEHFIQLAHELGLLV 119
Cdd:COG1874   2 TFLLD-KPFLILGGDYHPERWPPEVWAEDIRLMKAAGLNTVRIgYFAWNLHEPEEGVFDFDW---LDRFIDLLHEAGLKV 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 120 ILRPGPYIcaewdmggLPAWLLEKQSIVLR-----------------SSDPDYLVAVDKWLAVLLPKmkpllYQNGGPII 182
Cdd:COG1874  78 ILRTPTAA--------PPAWLLKKYPEILPvdadgrrrgfgsrrhycPSSPVYREAARRIVRALAER-----YGDHPAVI 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 183 TVQVENEYGSYFACDYDYLRF---LVHRF-----------------RYHLGNDVIL------------------FTTDGA 224
Cdd:COG1874 145 MWQVDNEYGSYDYCDACAAAFrdwLRERYgtldalneawgtafwsqRYTDWDEIEPprltpttanpslrldfrrFSSDQV 224
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 225 SE--KMLK----------------------------CGTLqDLYATVDFGTGNN---ITQAF--LVQRKFEPKGPLINSE 269
Cdd:COG1874 225 LEylRAQRdilreagpdvpvttnfmgpfpgldywklARDL-DVVSWDNYPDGSAadpDEIAFahDLMRGLKGGGPFMVME 303
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 270 FYTGWLdHWGKPHSTVKTKTLATSLYNLLARGAN-VNLYMfiggtnfaywngantpYEPQP--TSYDYDAPLSEAGDLTK 346
Cdd:COG1874 304 QWPGWV-NWGPYNPAKRPGQLRLWSLQALAHGADgVNYFQ----------------WRPSRggTEYDHDAPLDHAGRPTR 366
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448 347 KYFALREVIQMFKEVPEgpIPPSTPKfayGKVALrkfktVAEALGILcpngpvksLYPLTFTQVKQYFGYV-----LYRT 421
Cdd:COG1874 367 KFREVRELGAELARLPE--VPGSRVT---ARVAL-----LFDWESWW--------ALEIQSPPLGQDLGYVdlvraLYRA 428
                       490       500       510       520       530       540       550
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 26345448 422 TLpqdcsnpkpifsspfngvrdRAYVSVDGVPQGI-LDRN---LMTALNIRGKAGAT-LDILVENMGRVNYGRFI 491
Cdd:COG1874 429 LR--------------------RAGVTVDIVPPFAdLSGYkllVAPALYLVSDALAErLLAYVENGGRVNYGPRS 483
PLN03059 PLN03059
beta-galactosidase; Provisional
28-359 4.56e-47

beta-galactosidase; Provisional


Pssm-ID: 166698 [Multi-domain]  Cd Length: 840  Bit Score: 178.66  E-value: 4.56e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448   28 VTQRTFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEH 107
Cdd:PLN03059  23 VSHGSASVSYDHRAFIINGQRRILISGSIHYPRSTPEMWPDLIQKAKDGGLDVIQTYVFWNGHEPSPGNYYFEDRYDLVK 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  108 FIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKP--LLYQNGGPIITVQ 185
Cdd:PLN03059 103 FIKVVQAAGLYVHLRIGPYICAEWNFGGFPVWLKYVPGIEFRTDNGPFKAAMQKFTEKIVDMMKSekLFEPQGGPIILSQ 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  186 VENEYGSyfacdydylrflvhrFRYHLGNDVILFTTdGASEKMLKCGT-------LQDLYATVDFGTGNNI-TQAFLVQR 257
Cdd:PLN03059 183 IENEYGP---------------VEWEIGAPGKAYTK-WAADMAVKLGTgvpwvmcKQEDAPDPVIDTCNGFyCENFKPNK 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448  258 KFEPKgplINSEFYTGWLDHWGKPHSTVKTKTLATSLYNLLA-RGANVNLYMFIGGTNFAYWNGAntPYepQPTSYDYDA 336
Cdd:PLN03059 247 DYKPK---MWTEAWTGWYTEFGGAVPNRPAEDLAFSVARFIQnGGSFINYYMYHGGTNFGRTAGG--PF--IATSYDYDA 319
                        330       340
                 ....*....|....*....|....*
gi 26345448  337 PLSEAGdLTK--KYFALREVIQMFK 359
Cdd:PLN03059 320 PLDEYG-LPRepKWGHLRDLHKAIK 343
Glyco_hydro_42 pfam02449
Beta-galactosidase; This group of beta-galactosidase enzymes belong to the glycosyl hydrolase ...
62-197 2.14e-13

Beta-galactosidase; This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.


Pssm-ID: 396834  Cd Length: 376  Bit Score: 72.30  E-value: 2.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26345448    62 PRFYWEDRLLKMKMAGLNAIQM-YVPWNFHEPQPGQYEFSGdrdVEHFIQLAHELGLLVILRPGpyicaewdMGGLPAWL 140
Cdd:pfam02449   8 PEETWEEDIRLMKEAGVNVVRIgIFAWAKLEPEEGKYDFEW---LDEVIDLLAKAGIKVILATP--------TAAPPAWL 76
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 26345448   141 LEKQSIVLRS-----------------SDPDYLVAVDKWLAVLLPkmkplLYQNGGPIITVQVENEYG---SYFACD 197
Cdd:pfam02449  77 VKKHPEILPVdadgrrrgfgsrhhycpSSPVYREYAARIVEALAE-----RYGDHPALIGWHIDNEYGchvSECYCE 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH