NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|26341082|dbj|BAC34203|]
View 

unnamed protein product [Mus musculus]

Protein Classification

glycosyltransferase family 49 protein( domain architecture ID 10621298)

glycosyltransferase family 49 protein such as beta-1,4-glucuronyltransferase 1, which transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_49 pfam13896
Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the ...
 94-409 5.03e-137

Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the glycosylation of the alpha-dystroglycan subunit. Dystroglycan is an integral member of the skeletal muscular dystrophin glycoprotein complex, which links dystrophin to proteins in the extracellular matrix.


:

Pssm-ID: 464027  Cd Length: 327  Bit Score: 395.08  E-value: 5.03e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082    94 DVILATHASVDNLLHLSGLLERWEGPLSVSVFAATkEEAQLATVLAYALSSHCP--EMRARVAMHLVCPSRYeaaVPDPR 171
Cdd:pfam13896   1 DVTLATHGTVDFLDNLEPLVERWRGPISVAVFAPG-TDFSLALDYIAYLRRCFPseLVRENVTFHLVFPSEH---MPPKQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   172 EPGEFALLR---SCQEVFDKLARVAQPGINYALGTNTsYPNNLLRNLAREEAN--YALVIDVDMVPSEGLWRGLREMLDQ 246
Cdd:pfam13896  77 VTCPSALLSssnDCSELLSPLRKLVPPGANYAAQNLL-YPINLLRNVARKGAQthFVLVIDIDLYPSPGLAEKFLEFLAR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   247 SNHW----DGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES---LLRPAYVV 319
Cdd:pfam13896 156 NKKLlnrtSPCVFVVPAFEVDANATVPRTKAELLRLLKNGEARPFHHKVCPKCHKPTNYDRWLNLSKNSdglNLFVAYKV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   320 P-WRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYR 398
Cdd:pfam13896 236 TyWQDPWEPFYIGTRNDPLYDERFTWYGFDRISQVYELCVAGYEFHVLDNAFLVHKGIKETGYFHAAREAQNKKNRKLFR 315

                         330
                  ....*....|..
gi 26341082   399 -QFKQELKARYP 409
Cdd:pfam13896 316 sRFKQELKAKYP 327
 
Name Accession Description Interval E-value
Glyco_transf_49 pfam13896
Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the ...
 94-409 5.03e-137

Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the glycosylation of the alpha-dystroglycan subunit. Dystroglycan is an integral member of the skeletal muscular dystrophin glycoprotein complex, which links dystrophin to proteins in the extracellular matrix.


Pssm-ID: 464027  Cd Length: 327  Bit Score: 395.08  E-value: 5.03e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082    94 DVILATHASVDNLLHLSGLLERWEGPLSVSVFAATkEEAQLATVLAYALSSHCP--EMRARVAMHLVCPSRYeaaVPDPR 171
Cdd:pfam13896   1 DVTLATHGTVDFLDNLEPLVERWRGPISVAVFAPG-TDFSLALDYIAYLRRCFPseLVRENVTFHLVFPSEH---MPPKQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   172 EPGEFALLR---SCQEVFDKLARVAQPGINYALGTNTsYPNNLLRNLAREEAN--YALVIDVDMVPSEGLWRGLREMLDQ 246
Cdd:pfam13896  77 VTCPSALLSssnDCSELLSPLRKLVPPGANYAAQNLL-YPINLLRNVARKGAQthFVLVIDIDLYPSPGLAEKFLEFLAR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   247 SNHW----DGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES---LLRPAYVV 319
Cdd:pfam13896 156 NKKLlnrtSPCVFVVPAFEVDANATVPRTKAELLRLLKNGEARPFHHKVCPKCHKPTNYDRWLNLSKNSdglNLFVAYKV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   320 P-WRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYR 398
Cdd:pfam13896 236 TyWQDPWEPFYIGTRNDPLYDERFTWYGFDRISQVYELCVAGYEFHVLDNAFLVHKGIKETGYFHAAREAQNKKNRKLFR 315

                         330
                  ....*....|..
gi 26341082   399 -QFKQELKARYP 409
Cdd:pfam13896 316 sRFKQELKAKYP 327
 
Name Accession Description Interval E-value
Glyco_transf_49 pfam13896
Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the ...
 94-409 5.03e-137

Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the glycosylation of the alpha-dystroglycan subunit. Dystroglycan is an integral member of the skeletal muscular dystrophin glycoprotein complex, which links dystrophin to proteins in the extracellular matrix.


Pssm-ID: 464027  Cd Length: 327  Bit Score: 395.08  E-value: 5.03e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082    94 DVILATHASVDNLLHLSGLLERWEGPLSVSVFAATkEEAQLATVLAYALSSHCP--EMRARVAMHLVCPSRYeaaVPDPR 171
Cdd:pfam13896   1 DVTLATHGTVDFLDNLEPLVERWRGPISVAVFAPG-TDFSLALDYIAYLRRCFPseLVRENVTFHLVFPSEH---MPPKQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   172 EPGEFALLR---SCQEVFDKLARVAQPGINYALGTNTsYPNNLLRNLAREEAN--YALVIDVDMVPSEGLWRGLREMLDQ 246
Cdd:pfam13896  77 VTCPSALLSssnDCSELLSPLRKLVPPGANYAAQNLL-YPINLLRNVARKGAQthFVLVIDIDLYPSPGLAEKFLEFLAR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   247 SNHW----DGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEES---LLRPAYVV 319
Cdd:pfam13896 156 NKKLlnrtSPCVFVVPAFEVDANATVPRTKAELLRLLKNGEARPFHHKVCPKCHKPTNYDRWLNLSKNSdglNLFVAYKV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26341082   320 P-WRDPWEPFYVAGGKVPTFDERFRQYGFNRISQACELHVAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQRNKILYR 398
Cdd:pfam13896 236 TyWQDPWEPFYIGTRNDPLYDERFTWYGFDRISQVYELCVAGYEFHVLDNAFLVHKGIKETGYFHAAREAQNKKNRKLFR 315

                         330
                  ....*....|..
gi 26341082   399 -QFKQELKARYP 409
Cdd:pfam13896 316 sRFKQELKAKYP 327
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH