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Conserved domains on  [gi|254764822|sp|B4EWD2|]
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RecName: Full=Sec-independent protein translocase protein TatA

Protein Classification

Sec-independent protein translocase family protein( domain architecture ID 241)

Sec-independent protein translocase family protein such as Sec-independent protein translocase proteins TatA and TatB, which are part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Gene Ontology:  GO:0033281|GO:0043953

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TatA_B_E super family cl00788
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 1-87 1.76e-31

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


The actual alignment was detected with superfamily member PRK04598:

Pssm-ID: 445098  Cd Length: 81  Bit Score: 105.32  E-value: 1.76e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNNaekttNDADFDTKNLAQKTSTEEKSTt 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESAKANK-----KDADFEPKNLEQAKTEAAAEK- 74


                ....*..
gi 254764822 81 eSKNKEQ 87
Cdd:PRK04598 75 -KKDKEQ 80
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-87 1.76e-31

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 105.32  E-value: 1.76e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNNaekttNDADFDTKNLAQKTSTEEKSTt 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESAKANK-----KDADFEPKNLEQAKTEAAAEK- 74


                ....*..
gi 254764822 81 eSKNKEQ 87
Cdd:PRK04598 75 -KKDKEQ 80
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-71 2.06e-17

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 69.19  E-value: 2.06e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGD-ENQKETNNAEKTTNDADFDTKNLAQK 71
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEvKEELDEELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-48 2.07e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 66.09  E-value: 2.07e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 254764822   3 GISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQ 48
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-55 1.68e-09

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 48.84  E-value: 1.68e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 254764822   4 ISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAM-GDENQKETNNAE 55
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATkELEEEDEKEAQE 53
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-87 1.76e-31

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 105.32  E-value: 1.76e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNNaekttNDADFDTKNLAQKTSTEEKSTt 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESAKANK-----KDADFEPKNLEQAKTEAAAEK- 74


                ....*..
gi 254764822 81 eSKNKEQ 87
Cdd:PRK04598 75 -KKDKEQ 80
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-88 3.67e-27

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 94.74  E-value: 3.67e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKEtnnaEKTTNDADFDTKNLAQK-----TSTE 75
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQ----DKTSQDADFTAKTIADKqadtnQEQA 76

                        90
                ....*....|...
gi 254764822 76 EKSTTESKNKEQV 88
Cdd:PRK03554 77 KTEDAKRHDKEQV 89
tatA PRK01833
Sec-independent protein translocase subunit TatA;
1-87 8.28e-23

Sec-independent protein translocase subunit TatA;


Pssm-ID: 167284  Cd Length: 74  Bit Score: 83.00  E-value: 8.28e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKetnnaekttnDADFDTKNLAQKTSTEEKstt 80
Cdd:PRK01833  1 MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADDKPK----------DAEFEKVEAKEAASTEQK--- 67


                ....*..
gi 254764822 81 eSKNKEQ 87
Cdd:PRK01833 68 -AKEKEQ 73
tatA PRK02958
Sec-independent protein translocase subunit TatA;
1-67 6.10e-21

Sec-independent protein translocase subunit TatA;


Pssm-ID: 235091  Cd Length: 73  Bit Score: 78.08  E-value: 6.10e-21
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNNA----EKTTNDADFDTKN 67
Cdd:PRK02958  1 MGSFSIWHWLIVLVIVVLVFGTKKLRNIGSDLGGAVKGFKDGMKEGETPQEAQAqqlpDSGTIDVEAKEKS 71
tatE PRK01614
Sec-independent protein translocase subunit TatA;
1-84 2.18e-20

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 77.24  E-value: 2.18e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNN-AEKTTNDADFDTKNLAQKTSTEEKST 79
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDEVSTSVlGETKMSAETKTVAETKAASDSQAAAS 80


                ....*
gi 254764822 80 TESKN 84
Cdd:PRK01614 81 VERKD 85
tatE PRK03625
twin-arginine translocase subunit TatE;
1-59 2.41e-19

twin-arginine translocase subunit TatE;


Pssm-ID: 179612  Cd Length: 67  Bit Score: 74.03  E-value: 2.41e-19
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNNAEKTTN 59
Cdd:PRK03625  1 MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDAAAKKGADVDLQ 59
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-71 2.06e-17

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 69.19  E-value: 2.06e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGD-ENQKETNNAEKTTNDADFDTKNLAQK 71
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEvKEELDEELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-48 2.07e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 66.09  E-value: 2.07e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 254764822   3 GISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQ 48
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
3-58 3.79e-16

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 66.82  E-value: 3.79e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 254764822  3 GISIWQ-LLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDEnQKETNNAEKTT 58
Cdd:PRK00442  2 GIFDWKhWIVILVVVVLVFGTKKLKNLGSDVGESIKGFRKAMNED-EKEDKPAEQPA 57
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-74 6.49e-12

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 55.90  E-value: 6.49e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFK---KAMGDENQKEtnnAEKTTNDADFDTKNLAQKTST 74
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKsevKEMQSDNKAE---ASAAAAQAPYQVATPTPVQSQ 74
tatA PRK00720
twin-arginine translocase TatA/TatE family subunit;
1-83 8.13e-12

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234822  Cd Length: 78  Bit Score: 55.43  E-value: 8.13e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDEnqkETNNAEKTTNDADFDTKnlAQKTSTEEKSTT 80
Cdd:PRK00720  1 MGSFSIWHWLIVLAVVLLLFGRGKISELMGDVAKGIKSFKKGMADD---DAPPAEPPEPVRTIDHK--ADEPVAPVKKDV 75


                ...
gi 254764822 81 ESK 83
Cdd:PRK00720 76 GSK 78
tatA PRK04561
twin arginine translocase protein A; Provisional
 1-48 1.56e-11

twin arginine translocase protein A; Provisional


Pssm-ID: 179864  Cd Length: 75  Bit Score: 54.54  E-value: 1.56e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQ 48
Cdd:PRK04561  1 MGSFSIWHWLVVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDDK 48
tatA PRK14859
twin arginine translocase protein A; Provisional
 1-56 1.32e-10

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 51.65  E-value: 1.32e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKETNNAEK 56
Cdd:PRK14859  1 MFGIGMPELIVILVIVLIVFGAGKLPEIGGGLGKSIKNFKKATSEKEEIEIKPTKK 56
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-55 1.68e-09

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 48.84  E-value: 1.68e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 254764822   4 ISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAM-GDENQKETNNAE 55
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATkELEEEDEKEAQE 53
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-62 1.37e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 46.65  E-value: 1.37e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMgDENQKETNNAEKTTNDAD 62
Cdd:PRK14860  1 MFGFGMPELIVILVIALVVFGPAKLPQLGQALGGAIRNFKKAS-NEEDVVTINNEKGKEDQA 61
tatA PRK01470
twin arginine translocase protein A; Provisional
 3-50 4.88e-07

twin arginine translocase protein A; Provisional


Pssm-ID: 179298  Cd Length: 51  Bit Score: 42.53  E-value: 4.88e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 254764822  3 GISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAMGDENQKE 50
Cdd:PRK01470  2 GMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDN 49
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-55 5.58e-07

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 42.65  E-value: 5.58e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  1 MGGISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAM-----GDENQKETNNAE 55
Cdd:PRK14861  2 FSNIGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKATkeltdDDFQEKKKKEKM 61
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
3-87 3.35e-06

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 41.24  E-value: 3.35e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254764822  3 GISIWQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFKKAmGDENQKETNNAEKTTNDADFDTKNLAQKTSTEEKSTT-E 81
Cdd:PRK14857  5 GIGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEA-SKEFENEIKREMAEPEQEVKAPAELESNQTNEANQEQvD 83


                ....*.
gi 254764822 82 SKNKEQ 87
Cdd:PRK14857 84 AENSPE 89
tatA PRK00191
twin arginine translocase protein A; Provisional
 7-49 8.60e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 39.94  E-value: 8.60e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 254764822  7 WQLLIIAVIVVLLFGTNKLRTLGSDLGASVKGFK---KAMGDENQK 49
Cdd:PRK00191  6 WEIGIIVLLIIVLFGAKKLPDAARSIGRSMRIFKsevKEMSKDDQT 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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