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Conserved domains on  [gi|1331265782|gb|AUQ98631|]
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putative ATP-NAD kinase [Phaeobacter inhibens]

Protein Classification

NAD kinase( domain architecture ID 10012223)

ATP-dependent NAD kinase catalyzes the phosphorylation of NAD to NADP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 9-252 3.41e-162

inorganic polyphosphate/ATP-NAD kinase; Reviewed


:

Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 448.88  E-value: 3.41e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   9 ASRAPVAQSAQTEMVRRYGNVPREEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYSASGLLARLQAAE 88
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYSEDDLLERIAAAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  89 EEIINPLSMVAMDGEGRSHRALAINEVSLLRAGPQAAKLKISVDGRQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIG 168
Cdd:PRK04761   81 PTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 169 SDVLALTAIAAFRPRRWRGALLPSNAIVRFDVLEPEKRPVMADADSVSFANIRWVEIATQTKIRHKILFDPGHGLEERLI 248
Cdd:PRK04761  161 SNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERIL 240


                  ....
gi 1331265782 249 SEQF 252
Cdd:PRK04761  241 AEQF 244
 
Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 9-252 3.41e-162

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 448.88  E-value: 3.41e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   9 ASRAPVAQSAQTEMVRRYGNVPREEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYSASGLLARLQAAE 88
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYSEDDLLERIAAAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  89 EEIINPLSMVAMDGEGRSHRALAINEVSLLRAGPQAAKLKISVDGRQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIG 168
Cdd:PRK04761   81 PTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 169 SDVLALTAIAAFRPRRWRGALLPSNAIVRFDVLEPEKRPVMADADSVSFANIRWVEIATQTKIRHKILFDPGHGLEERLI 248
Cdd:PRK04761  161 SNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERIL 240


                  ....
gi 1331265782 249 SEQF 252
Cdd:PRK04761  241 AEQF 244
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-252 1.27e-74

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 228.10  E-value: 1.27e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   5 IAFLASR-APVAQSAQTEMVRRYGNVPREEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYS--ASGLL 81
Cdd:COG0061    23 AELLEERgIEVVLDEDTAVPGVPLEELGEEADLVIVLGGDGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPeeLEEAL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  82 ARLQAAEEEIINPLSMVA--MDGEGRSHRALAINEVSLLRAGP-QAAKLKISVDGRqRMAELVCDGALVSTPAGSTAYNY 158
Cdd:COG0061   103 ERLLAGEYEVEERLLLEAtvDRDGEVVHEALALNEVVVLRGSIaRMIELEVYIDGE-FLEEFRGDGLIVSTPTGSTAYNL 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 159 SAHGPILPIGSDVLALTAIAAFRPrRWRGALLPSNAIVRFDVLEPEkRPVMADADSVSFANIR---WVEIaTQTKIRHKI 235
Cdd:COG0061   182 SAGGPIVHPGLDALVLTPIAPHTL-SSRPLVLPDDSEIEIEVLEDS-RPAVLVADGQEVRDLEpgdRVEI-RRSPKPVRL 258

                         250
                  ....*....|....*..
gi 1331265782 236 LFDPGHGLEERLiSEQF 252
Cdd:COG0061   259 LRLKDHSFFERL-REKL 274
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 112-183 5.04e-09

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 53.07  E-value: 5.04e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331265782 112 INEVSLLRA-GPQAAKLKISVDGRQrMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIA----AFRPR 183
Cdd:pfam20143   1 LNEVVYVRGpGATMIEFELYVDGEL-LGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICphslSSRPI 76
 
Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 9-252 3.41e-162

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 448.88  E-value: 3.41e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   9 ASRAPVAQSAQTEMVRRYGNVPREEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYSASGLLARLQAAE 88
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYSEDDLLERIAAAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  89 EEIINPLSMVAMDGEGRSHRALAINEVSLLRAGPQAAKLKISVDGRQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIG 168
Cdd:PRK04761   81 PTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 169 SDVLALTAIAAFRPRRWRGALLPSNAIVRFDVLEPEKRPVMADADSVSFANIRWVEIATQTKIRHKILFDPGHGLEERLI 248
Cdd:PRK04761  161 SNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERIL 240


                  ....
gi 1331265782 249 SEQF 252
Cdd:PRK04761  241 AEQF 244
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-252 1.27e-74

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 228.10  E-value: 1.27e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   5 IAFLASR-APVAQSAQTEMVRRYGNVPREEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYS--ASGLL 81
Cdd:COG0061    23 AELLEERgIEVVLDEDTAVPGVPLEELGEEADLVIVLGGDGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPeeLEEAL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  82 ARLQAAEEEIINPLSMVA--MDGEGRSHRALAINEVSLLRAGP-QAAKLKISVDGRqRMAELVCDGALVSTPAGSTAYNY 158
Cdd:COG0061   103 ERLLAGEYEVEERLLLEAtvDRDGEVVHEALALNEVVVLRGSIaRMIELEVYIDGE-FLEEFRGDGLIVSTPTGSTAYNL 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 159 SAHGPILPIGSDVLALTAIAAFRPrRWRGALLPSNAIVRFDVLEPEkRPVMADADSVSFANIR---WVEIaTQTKIRHKI 235
Cdd:COG0061   182 SAGGPIVHPGLDALVLTPIAPHTL-SSRPLVLPDDSEIEIEVLEDS-RPAVLVADGQEVRDLEpgdRVEI-RRSPKPVRL 258

                         250
                  ....*....|....*..
gi 1331265782 236 LFDPGHGLEERLiSEQF 252
Cdd:COG0061   259 LRLKDHSFFERL-REKL 274
ppnK PRK03708
NAD(+) kinase;
24-210 2.55e-18

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 81.68  E-value: 2.55e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  24 RRYGNVPREE--ADVIVALGGDGFMLDTLHETiDLPAPVYGMNRGTIGFLM-----NEYSA-SGLLARLQAAEEEIinpL 95
Cdd:PRK03708   46 SEEDVLPLEEmdVDFIIAIGGDGTILRIEHKT-KKDIPILGINMGTLGFLTevepeETFFAlSRLLEGDYFIDERI---K 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  96 SMVAMDGEGRSHralAINEVSLLRAGP-QAAKLKISVDGrQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLAL 174
Cdd:PRK03708  122 LRVYINGENVPD---ALNEVVILTGIPgKIIHLKYYVDG-ELADEVRADGLIISTPTGSTAYAMSAGGPFVDPRLDAILI 197

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1331265782 175 TAIAAFrPRRWRGALLPSNAIVRFDVLEPEKRPVMA 210
Cdd:PRK03708  198 APLCPF-KLSSRPMVVPSSSRIDVKLLRTGREIILV 232
ppnK PRK02155
NAD kinase;
15-178 4.49e-17

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 78.44  E-value: 4.49e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  15 AQSAQTEMVRRYGNVPREE----ADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFL----MNEYSASglLARLQA 86
Cdd:PRK02155   41 ADTARNIGLTGYPALTPEEigarADLAVVLGGDGTMLGIGRQLAPYGVPLIGINHGRLGFItdipLDDMQET--LPPMLA 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  87 AEEEIINPLSMVA--MDGEGRSHRALAINEVSLLRAGPQA-AKLKISVDGRqRMAELVCDGALVSTPAGSTAYNYSAHGP 163
Cdd:PRK02155  119 GNYEEEERMLLEArvVRDGEPIFHALAFNDVVVNRSGFSGmVELRVSVDGR-FMYNQRSDGLIVATPTGSTAYALSAGGP 197

                         170
                  ....*....|....*
gi 1331265782 164 ILPIGSDVLALTAIA 178
Cdd:PRK02155  198 ILHPQLPGWVLVPIA 212
pnk PRK14077
NAD(+) kinase;
33-198 4.61e-17

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 78.67  E-value: 4.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  33 EADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFL----MNEysASGLLARLQAAEEEIINP--LSMVAMDGEGRS 106
Cdd:PRK14077   64 ISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLtditVDE--AEKFFQAFFQGEFEIEKPymLSVFLEKKQGKI 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 107 HRALAINEVSLLRAGpQAAKLKISV-DGRQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIAAFRPRRw 185
Cdd:PRK14077  142 LEKLAFNDVVISKNN-QASMAHIEAfLNEKYFNEYFGDGVIVATPAGSTAYNMSANGPIIYPLSQVFILTPVCSHSLTQ- 219

                         170
                  ....*....|...
gi 1331265782 186 RGALLPSNAIVRF 198
Cdd:PRK14077  220 RPIVLPKGFEVEF 232
ppnK PRK01231
NAD(+) kinase;
16-165 3.33e-15

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 73.45  E-value: 3.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  16 QSAQTEMVRRYGNVPR----EEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMN------EYSASGLLARLQ 85
Cdd:PRK01231   41 ETAEVLPGHGLQTVSRkllgEVCDLVIVVGGDGSLLGAARALARHNVPVLGINRGRLGFLTDirpdelEFKLAEVLDGHY 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  86 AAEEEIInpLSMVAMDGEGRSHRALAINEVSLLRAgpQAAKL---KISVDGrqrmaELVC----DGALVSTPAGSTAYNY 158
Cdd:PRK01231  121 QEEERFL--LEAEVRRGGEVIGQGDALNDVVLHPG--KSTRMiefELYIDG-----QFVCsqrsDGLIVSTPTGSTAYAL 191


                  ....*..
gi 1331265782 159 SAHGPIL 165
Cdd:PRK01231  192 SGGGPIM 198
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 34-177 3.86e-15

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 73.35  E-value: 3.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  34 ADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMN---EYSASGLLARLQA---AEEEIINPLSMVAMDGEgrSH 107
Cdd:PRK04539   69 CDLVAVLGGDGTFLSVAREIAPRAVPIIGINQGHLGFLTQiprEYMTDKLLPVLEGkylAEERILIEAALIREGKT--AE 146

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1331265782 108 RALAINEVSLLRAGP-QAAKLKISVDgRQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAI 177
Cdd:PRK04539  147 RALALNDAVLSRGGAgQMIEFEVFVN-REFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPI 216
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 33-200 3.33e-14

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 70.34  E-value: 3.33e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  33 EADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFL--MNEYSASGLLARLQAAEEEIiNPLSMVAMDGEGRSHRAL 110
Cdd:PRK01911   64 SADMVISIGGDGTFLRTATYVGNSNIPILGINTGRLGFLatVSKEEIEETIDELLNGDYTI-EERSLLQLESNPKLFGEL 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 111 --AINEVSLLRAGPQAAklkISV----DGrQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIAA----F 180
Cdd:PRK01911  143 nfALNEIAILKRDTSSM---ITVhtylNG-EYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPhnlnV 218

                         170       180
                  ....*....|....*....|
gi 1331265782 181 RPrrwrgALLPSNAIVRFDV 200
Cdd:PRK01911  219 RP-----LVIPDDTEITLEV 233
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 8-165 1.08e-13

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 69.18  E-value: 1.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   8 LASRAPVAQSAQTEMVRRYGNVPREEADVIVALGGDGFML---DTLHETidlPAPVYGMNRGTIGFLMnEYSASGL---L 81
Cdd:PRK03372   47 LGATHPAPDDFRAMEVVDADPDAADGCELVLVLGGDGTILraaELARAA---DVPVLGVNLGHVGFLA-EAEAEDLdeaV 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  82 ARLQAAEEEIINPLSM---VAMDGEGRsHRALAINEVSLLRAGPQAA-KLKISVDGRQrMAELVCDGALVSTPAGSTAYN 157
Cdd:PRK03372  123 ERVVDRDYRVEERMTLdvtVRVGGEIV-WRGWALNEASLEKADREGMlEVVLEVDGRP-VSSFGCDGVLVSTPTGSTAYA 200


                  ....*...
gi 1331265782 158 YSAHGPIL 165
Cdd:PRK03372  201 FSAGGPVV 208
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
37-181 4.40e-13

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 68.22  E-value: 4.40e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  37 IVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLmNEYSASGLLARLQA---AEEEII--NPLSMVAMDGEGRSHRALA 111
Cdd:PRK14076  352 IISIGGDGTVLRASKLVNGEEIPIICINMGTVGFL-TEFSKEEIFKAIDSiisGEYEIEkrTKLSGFILKDGHQNILPSA 430

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1331265782 112 INEVSLLRAGPqaAKL---KISVDGrQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIAAFR 181
Cdd:PRK14076  431 LNEVVITTKNP--AKMlhfEVYVNG-ELVEEVRADGIIISTPTGSTAYSLSAGGPIVEPTVDGFIIVPICPFK 500
ppnK PRK02649
NAD(+) kinase;
38-178 7.00e-13

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 66.93  E-value: 7.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  38 VALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYsasglLARLQAAEEEIINP---------LSMVAMDGEGRSHR 108
Cdd:PRK02649   73 IVLGGDGTVLSAARQLAPCGIPLLTINTGHLGFLTEAY-----LNQLDEAIDQVLAGqytieertmLTVSVMRGDQLRWE 147

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1331265782 109 ALAINEVSLLRAgPQAA--KLKISVdGRQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIA 178
Cdd:PRK02649  148 ALSLNEMVLHRE-PLTSmcHFEIAI-GRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPDVPVLQLTPIC 217
pnk PRK14075
NAD(+) kinase;
30-202 1.04e-12

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 65.91  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  30 PREEADVIVALGGDGFMLDTLHETidlPAPVYGMNRGTIGFL----MNEYSAsgLLARL--QAAEEEIinpLSMVAMDGE 103
Cdd:PRK14075   38 GKVTADLIIVVGGDGTVLKAAKKV---GTPLVGFKAGRLGFLssytLEEIDR--FLEDLknWNFREEK---RWFLKIESE 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 104 GRSHraLAINEVSLLRAGPQA-AKLKISVDGRQRMAeLVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIAafrP 182
Cdd:PRK14075  110 LGNH--LALNDVTLERDPSQKmVEIEVSFEDHSSMW-FFADGVVISTPTGSTAYSLSLGGPIILPNCEVFEITPIA---P 183

                         170       180
                  ....*....|....*....|..
gi 1331265782 183 RRW--RGALLPSNAIVRFDVLE 202
Cdd:PRK14075  184 QFLatRSIVIPSNEKVTVESQR 205
ppnK PRK01185
NAD(+) kinase;
34-200 2.21e-12

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 65.22  E-value: 2.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  34 ADVIVALGGDGFMLDTLHETidlPAPVYGMNRGTIGFL----MNEYSASglLARLQAAEEEIINPLSM-VAMDGEgRSHR 108
Cdd:PRK01185   53 ADVIITIGGDGTILRTLQRA---KGPILGINMGGLGFLteieIDEVGSA--IKKLIRGEYFIDERMKLkVYINGE-RLED 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 109 AlaINEVSLLRAgpQAAKL---KISVDGrQRMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIAAFRpRRW 185
Cdd:PRK01185  127 C--TNEAVIHTD--RIAKIrqfKIYYDG-HFLDTFKADGVIVATPTGSTSYSSSAGGPILLPNLEGMVISYIAPYS-SRP 200

                         170
                  ....*....|....*
gi 1331265782 186 RGALLPSNAIVRFDV 200
Cdd:PRK01185  201 KSVVVPSESTVEIKI 215
ppnK PRK02231
NAD(+) kinase;
34-174 6.86e-11

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 60.97  E-value: 6.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  34 ADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLM-----NEYSAsgLLARLQAAE---EEIINPLSMVAMDGEGR 105
Cdd:PRK02231   43 AQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFLTdidpkNAYEQ--LEACLERGEffvEERFLLEAKIERNGKII 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1331265782 106 ShRALAINEVSLLRAgpQAAKL---KISVDGR----QRmaelvCDGALVSTPAGSTAYNYSAHGPILPIGSDVLAL 174
Cdd:PRK02231  121 A-TSNALNEVVIHPA--KIAHMidfHVYIDDKfafsQR-----SDGLIISTPTGSTAYSLSAGGPILTPNLNAIAL 188
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 32-165 5.64e-10

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 58.41  E-value: 5.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  32 EEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEYSASGLLARLQAAEEEIINPL-----SMVAMDGEGRS 106
Cdd:PRK03378   62 QQADLAIVVGGDGNMLGAARVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKrflleAQVCRHGQQKR 141

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1331265782 107 HRAlAINEVsLLRAGPQAAKLKISV--DGR----QRmaelvCDGALVSTPAGSTAYNYSAHGPIL 165
Cdd:PRK03378  142 IST-AINEV-VLHPGKVAHMIEFEVyiDDNfafsQR-----SDGLIISTPTGSTAYSLSAGGPIL 199
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 112-183 5.04e-09

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 53.07  E-value: 5.04e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331265782 112 INEVSLLRA-GPQAAKLKISVDGRQrMAELVCDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIA----AFRPR 183
Cdd:pfam20143   1 LNEVVYVRGpGATMIEFELYVDGEL-LGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICphslSSRPI 76
ppnK PRK02645
NAD(+) kinase;
35-177 5.63e-08

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 52.61  E-value: 5.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  35 DVIVALGGDGFMLDTLHETIDLPAPVYGMN-RGTIGFLMNEYSA---SGLLARLQAAEEEIINPLSMVAMDGEGR----- 105
Cdd:PRK02645   59 DLAIVLGGDGTVLAAARHLAPHDIPILSVNvGGHLGFLTHPRDLlqdESVWDRLQEDRYAIERRMMLQARVFEGDrsnee 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 106 --SHRALAINEVSLLRAGPQ---AAKLKISVDGrqrmaELV----CDGALVSTPAGSTAYNYSAHGPILPIGSDVLALTA 176
Cdd:PRK02645  139 pvSESYYALNDFYLKPASEDrspTCILELEIDG-----EVVdqyqGDGLIVSTPTGSTAYTMAAGGPILHPGIDAIIVTP 213


                  .
gi 1331265782 177 I 177
Cdd:PRK02645  214 I 214
ppnK PRK03501
NAD kinase;
32-186 5.02e-06

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 46.51  E-value: 5.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  32 EEADVIVALGGDGFMLDTLHETIDLPAPVY-GMNR-GTIGFLMnEYSASGLLARLQAAEEEIIN----PLSMVAMDGEGR 105
Cdd:PRK03501   38 KNANIIVSIGGDGTFLQAVRKTGFREDCLYaGISTkDQLGFYC-DFHIDDLDKMIQAITKEEIEvrkyPTIEVTVDGSTS 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782 106 SHralAINEVSLLRAGPQAAKLKISVDGrQRMAELVCDGALVSTPAGSTAYNYSAHG----PILPigsdVLALTAIAAFR 181
Cdd:PRK03501  117 FY---CLNEFSIRSSIIKTFVIDVYIDD-LHFETFRGDGMVVSTPTGSTAYNKSVRGavvdPLIP----CFQVSELASLN 188


                  ....*
gi 1331265782 182 PRRWR 186
Cdd:PRK03501  189 NNTYR 193
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 3-178 6.18e-06

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 46.35  E-value: 6.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   3 MRIAFLASRAPVAQSAQTEMVRRYGNVP----REEADVIVALGGDGFMLDTLHETIDLPAPV--YGMNRGTIGFLMN--E 74
Cdd:PRK04885    1 MKVAIISNGDPKSKRVASKLKKYLKDFGfildEKNPDIVISVGGDGTLLSAFHRYENQLDKVrfVGVHTGHLGFYTDwrP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  75 YSASGLLARLQAAEEEIIN-PLSMVAMD-GEGRSHRALAINEvsllragpqaAKLKiSVDGrqrmaELVC---------- 142
Cdd:PRK04885   81 FEVDKLVIALAKDPGQVVSyPLLEVKITyEDGEKEKYLALNE----------ATIK-RIEG-----TLVAdvyingvlfe 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1331265782 143 ----DGALVSTPAGSTAYNYSAHGPILPIGSDVLALTAIA 178
Cdd:PRK04885  145 rfrgDGLCVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIA 184
ppnK PRK00561
NAD(+) kinase;
3-174 4.34e-05

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 43.71  E-value: 4.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782   3 MRIAFLASRAPVAQSAQTEM--VRRYGNVPREEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFL--MNEYSA- 77
Cdd:PRK00561    1 MKYKIFASTTPQTEPVLPKLkkVLKKKLAVEDGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYtsFNETDLd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  78 SGLLARLQAAEEEIINPLSmVAMDGegrsHRALAINEVSLLRAgpQAAKLKISVDGrQRMAELVCDGALVSTPAGSTAYN 157
Cdd:PRK00561   81 QNFANKLDQLKFTQIDLLE-VQIDD----QIHLVLNELAVYTN--TAYPINIFIDN-EFWEKYRGSGLLIGPRTGSTALA 152

                         170
                  ....*....|....*..
gi 1331265782 158 YSAHGPILPIGSDVLAL 174
Cdd:PRK00561  153 KSAKGAVIFPRIDVIQI 169
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 34-71 1.07e-04

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 40.81  E-value: 1.07e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1331265782  34 ADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFL 71
Cdd:pfam01513  74 VDLIIVLGGDGTALRAARLLQKAVIPILGVNTGVLGFL 111
PLN02727 PLN02727
NAD kinase
 32-215 7.39e-04

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 40.64  E-value: 7.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  32 EEADVIVALGGDGFMLDTLHETIDLPAPVYGMNRGTIGFLMNEY----------------SASG----LLARLQAaeeEI 91
Cdd:PLN02727  742 ERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYfedfrqdlrqvihgnnTLDGvyitLRMRLRC---EI 818

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331265782  92 InplsmvamdgegRSHRAL------AINEVSLLRaGPQAAKLKISVDGRQRMAELV-CDGALVSTPAGSTAYNYSAHGPI 164
Cdd:PLN02727  819 F------------RNGKAMpgkvfdVLNEVVVDR-GSNPYLSKIECYEHDRLITKVqGDGVIVATPTGSTAYSTAAGGSM 885

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1331265782 165 LPIGSDVLALTAIA----AFRPrrwrgALLP--------------SNAIVRFDvlePEKRPVMADADSV 215
Cdd:PLN02727  886 VHPNVPCMLFTPICphslSFRP-----VILPdsarlelkipddarSNAWVSFD---GKRRQQLSRGDSV 946
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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