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Conserved domains on  [gi|1277644206|gb|ATW16538|]
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cytidylate kinase [Chlamydia trachomatis]

Protein Classification

(d)CMP kinase( domain architecture ID 11129747)

(d)CMP kinase catalyzes the phosphorylation of cytidine monophosphate (CMP) or dCMP to produce cytidine diphosphate (CDP) or dCDP, using ATP as the preferred phosphoryl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 3-213 1.47e-105

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


:

Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 302.69  E-value: 1.47e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   3 ITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ---PDWQEVPLEDFLASPPFSFSFSKdsplqAFYGDRL 79
Cdd:pfam02224   1 IAIDGPSGSGKSTVARILARKLGYKYLDTGAMYRALALAALRqkvDLTDEDALAELASEVDISFGHTE-----VFLNGED 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  80 LTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQG- 158
Cdd:pfam02224  76 VSSEIRTDEVAQAASQVAAIPAVRARLNKLQRQLAKNGNIVMEGRDIGTVVFPDAEVKIFLTASPEERAKRRYKQLQAKg 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1277644206 159 -SLSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLIPS 213
Cdd:pfam02224 156 lSVDFEELLAEIKRRDKRDSERAVGPLKPAPDALIIDTSKLTIEEVVEKILELIKQ 211
 
Name Accession Description Interval E-value
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 3-213 1.47e-105

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 302.69  E-value: 1.47e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   3 ITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ---PDWQEVPLEDFLASPPFSFSFSKdsplqAFYGDRL 79
Cdd:pfam02224   1 IAIDGPSGSGKSTVARILARKLGYKYLDTGAMYRALALAALRqkvDLTDEDALAELASEVDISFGHTE-----VFLNGED 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  80 LTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQG- 158
Cdd:pfam02224  76 VSSEIRTDEVAQAASQVAAIPAVRARLNKLQRQLAKNGNIVMEGRDIGTVVFPDAEVKIFLTASPEERAKRRYKQLQAKg 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1277644206 159 -SLSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLIPS 213
Cdd:pfam02224 156 lSVDFEELLAEIKRRDKRDSERAVGPLKPAPDALIIDTSKLTIEEVVEKILELIKQ 211
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
1-215 7.30e-89

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 260.73  E-value: 7.30e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQpdwQEVPLED------FLASPPFSFSFSKDSPlQAF 74
Cdd:COG0283     1 PVIAIDGPAGSGKSTVAKALAKRLGYHYLDTGAMYRAVALAALR---NGIDLDDeealaaLARNLDIEFETDPGGQ-RVF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  75 YGDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKD 154
Cdd:COG0283    77 LNGEDVTDEIRTEEVSNAVSKVAAIPEVREALVALQRAFAKAPGLVADGRDIGTVVFPDAELKIFLTASAEERARRRYKE 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1277644206 155 LP-QG-SLSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLIPSHL 215
Cdd:COG0283   157 LKeKGiSVSLEELLADIKERDERDSTRAVAPLKPAEDAIVIDTTDLSIEEVVEKILALVRERL 219
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 1-211 3.06e-62

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 193.03  E-value: 3.06e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQpdwQEVPLEDFLASPPF----SFSFSKDSPLQA-FY 75
Cdd:TIGR00017   3 MIIAIDGPSGAGKSTVAKAVAEKLGYAYLDSGAMYRAIALAALQ---NRVDLTSEDALAELishlDIRFIPTNGEVEvFL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  76 GDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDL 155
Cdd:TIGR00017  80 NGEDVSEAIRTQEVANAASKVAVFPKVREALLKRQQALAKNDGIIADGRDIGTVVFPNAEVKIFLDASVEERAKRRYKQL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1277644206 156 PQGSLSK--EALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLI 211
Cdd:TIGR00017 160 QIKGNEVnfEELLAEIKERDDRDSNREVAPLKKADDALYLDTSNLSIDEVVEKILEYA 217
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 2-196 4.02e-56

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 174.98  E-value: 4.02e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLYCNTGamyrtlayarlqpdwqevpledflasppfsfsfskdsplqafygdrllt 81
Cdd:cd02020     1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTG------------------------------------------------- 31

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  82 sELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQG--S 159
Cdd:cd02020    32 -GIRTEEVGKLASEVAAIPEVRKALDERQRELAKKPGIVLEGRDIGTVVFPDADLKIFLTASPEVRAKRRAKQLQAKgeG 110

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1277644206 160 LSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSS 196
Cdd:cd02020   111 VDLEEILAEIIERDERDSTRYVAPLKLAEDAIVIDTS 147
PRK13477 PRK13477
bifunctional pantoate--beta-alanine ligase/(d)CMP kinase;
2-210 1.20e-53

bifunctional pantoate--beta-alanine ligase/(d)CMP kinase;


Pssm-ID: 237393 [Multi-domain]  Cd Length: 512  Bit Score: 179.31  E-value: 1.20e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ----PDwQEVPLEDFLASPPFSFSFSKDSPLQAFYGD 77
Cdd:PRK13477  286 IIAIDGPAGAGKSTVTRAVAKKLGLLYLDTGAMYRAVTWLVLQegidPQ-DEEALAELLSDLKIELKPSSGSPQRVWING 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  78 RLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDL-P 156
Cdd:PRK13477  365 EDVTEAIRSPEVTSSVSAIAAQPAVRQALVKQQQRIGEKGGLVAEGRDIGTHVFPDAELKIFLTASVEERARRRALDLqA 444

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1277644206 157 QGS--LSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPL 210
Cdd:PRK13477  445 QGFpvIDLEQLEAQIAERDRLDSTREIAPLRKADDAIELITDGLSIEEVVDKIIDL 500
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 2-44 6.50e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 38.89  E-value: 6.50e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1277644206    2 IITIDGPSGTGKSTLAKALAQTLQ-----FLYCNTGAMYRTLAYARLQ 44
Cdd:smart00382   4 VILIVGPPGSGKTTLARALARELGppgggVIYIDGEDILEEVLDQLLL 51
 
Name Accession Description Interval E-value
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 3-213 1.47e-105

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 302.69  E-value: 1.47e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   3 ITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ---PDWQEVPLEDFLASPPFSFSFSKdsplqAFYGDRL 79
Cdd:pfam02224   1 IAIDGPSGSGKSTVARILARKLGYKYLDTGAMYRALALAALRqkvDLTDEDALAELASEVDISFGHTE-----VFLNGED 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  80 LTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQG- 158
Cdd:pfam02224  76 VSSEIRTDEVAQAASQVAAIPAVRARLNKLQRQLAKNGNIVMEGRDIGTVVFPDAEVKIFLTASPEERAKRRYKQLQAKg 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1277644206 159 -SLSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLIPS 213
Cdd:pfam02224 156 lSVDFEELLAEIKRRDKRDSERAVGPLKPAPDALIIDTSKLTIEEVVEKILELIKQ 211
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
1-215 7.30e-89

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 260.73  E-value: 7.30e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQpdwQEVPLED------FLASPPFSFSFSKDSPlQAF 74
Cdd:COG0283     1 PVIAIDGPAGSGKSTVAKALAKRLGYHYLDTGAMYRAVALAALR---NGIDLDDeealaaLARNLDIEFETDPGGQ-RVF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  75 YGDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKD 154
Cdd:COG0283    77 LNGEDVTDEIRTEEVSNAVSKVAAIPEVREALVALQRAFAKAPGLVADGRDIGTVVFPDAELKIFLTASAEERARRRYKE 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1277644206 155 LP-QG-SLSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLIPSHL 215
Cdd:COG0283   157 LKeKGiSVSLEELLADIKERDERDSTRAVAPLKPAEDAIVIDTTDLSIEEVVEKILALVRERL 219
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 1-211 3.06e-62

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 193.03  E-value: 3.06e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQpdwQEVPLEDFLASPPF----SFSFSKDSPLQA-FY 75
Cdd:TIGR00017   3 MIIAIDGPSGAGKSTVAKAVAEKLGYAYLDSGAMYRAIALAALQ---NRVDLTSEDALAELishlDIRFIPTNGEVEvFL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  76 GDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDL 155
Cdd:TIGR00017  80 NGEDVSEAIRTQEVANAASKVAVFPKVREALLKRQQALAKNDGIIADGRDIGTVVFPNAEVKIFLDASVEERAKRRYKQL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1277644206 156 PQGSLSK--EALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPLI 211
Cdd:TIGR00017 160 QIKGNEVnfEELLAEIKERDDRDSNREVAPLKKADDALYLDTSNLSIDEVVEKILEYA 217
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 2-196 4.02e-56

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 174.98  E-value: 4.02e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLYCNTGamyrtlayarlqpdwqevpledflasppfsfsfskdsplqafygdrllt 81
Cdd:cd02020     1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTG------------------------------------------------- 31

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  82 sELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDLPQG--S 159
Cdd:cd02020    32 -GIRTEEVGKLASEVAAIPEVRKALDERQRELAKKPGIVLEGRDIGTVVFPDADLKIFLTASPEVRAKRRAKQLQAKgeG 110

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1277644206 160 LSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSS 196
Cdd:cd02020   111 VDLEEILAEIIERDERDSTRYVAPLKLAEDAIVIDTS 147
PRK13477 PRK13477
bifunctional pantoate--beta-alanine ligase/(d)CMP kinase;
2-210 1.20e-53

bifunctional pantoate--beta-alanine ligase/(d)CMP kinase;


Pssm-ID: 237393 [Multi-domain]  Cd Length: 512  Bit Score: 179.31  E-value: 1.20e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ----PDwQEVPLEDFLASPPFSFSFSKDSPLQAFYGD 77
Cdd:PRK13477  286 IIAIDGPAGAGKSTVTRAVAKKLGLLYLDTGAMYRAVTWLVLQegidPQ-DEEALAELLSDLKIELKPSSGSPQRVWING 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  78 RLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDL-P 156
Cdd:PRK13477  365 EDVTEAIRSPEVTSSVSAIAAQPAVRQALVKQQQRIGEKGGLVAEGRDIGTHVFPDAELKIFLTASVEERARRRALDLqA 444

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1277644206 157 QGS--LSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKILPL 210
Cdd:PRK13477  445 QGFpvIDLEQLEAQIAERDRLDSTREIAPLRKADDAIELITDGLSIEEVVDKIIDL 500
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
2-208 4.18e-45

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 158.67  E-value: 4.18e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQpdwQEVPLED------FLASPPFSFSFSkdsplQAFY 75
Cdd:PRK11860  444 VICIDGPTASGKGTVAARVAEALGYHYLDSGALYRLTALAALR---AGVALDDeaaiaaLARGLPVRFEGD-----RIWL 515

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  76 GDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKDL 155
Cdd:PRK11860  516 GGEDVTDAIRTEAAGMGASRVSALPAVRAALLALQRSFRRLPGLVADGRDMGTVIFPDAALKVFLTASAEARAERRYKQL 595

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1277644206 156 -PQG-SLSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLTISQILEKIL 208
Cdd:PRK11860  596 iSKGiSANIADLLADLEARDARDTQRSVAPLKPAQDALLLDNSDLTIEQAVAQVL 650
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 2-211 5.67e-40

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 144.94  E-value: 5.67e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQ----PDWQEVP-------LEDFLASPPFSFSFSKDSP 70
Cdd:PRK09518    3 IVAIDGPAGVGKSSVSRALAQYLGYAYLDTGAMYRACAWWCLKqgidLDAELVDeqvvteaVGEFFTGLHFDISVDPDSP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  71 lQAFYGDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYA----------TVGNCVFEGRDMGSKVFPHAEVKIFL 140
Cdd:PRK09518   83 -GVFADGEDISEEIRSPEVSSHVSAVAAIPPVRNVLIAAQRAYIareasadsfsGGLGIVAEGRDITTVVAPDAEVRILL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1277644206 141 TAKPEIRAERRLKDLPQgsLSKEALMAELIARDQADqQRECDPLVIPQDAIVIDSSNLTISQILEKILPLI 211
Cdd:PRK09518  162 TAREEVRQARRSGQDRS--ETPGVVLEDVAARDEAD-SKVTSFLSAADGVTTLDNSDLDFDETLDLLIGLV 229
PRK12269 PRK12269
bifunctional cytidylate kinase/ribosomal protein S1; Provisional
 1-207 2.38e-20

bifunctional cytidylate kinase/ribosomal protein S1; Provisional


Pssm-ID: 105491 [Multi-domain]  Cd Length: 863  Bit Score: 88.62  E-value: 2.38e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARLQP------------------------------DWQEV 50
Cdd:PRK12269   35 VIIALDGPAGSGKSSVCRLLASRLGAQCLNTGSFYRAFTLAALRRvselavqacspspdpdaavgcaavphatnlDTSYA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  51 PL----EDFLASPPFSFSFSKDSPLQ-----AFYGDRLLTSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVF 121
Cdd:PRK12269  115 PLtaqkKVALFDEAYWVSFARTVALSyragvMYVGEENVESLLRSDEVESAVSYFAAMPAIRAIMTGKIRSAVCGARVVC 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206 122 EGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKdlpQGS--LSKEALMAELIARDQADQQRECDPLVIPQDAIVIDSSNLT 199
Cdd:PRK12269  195 EGRDLTTVVFVDADLKCYLDASIEARVARRWA---QGTsrLSKQELEQRMRARDAHDRARTVGGLRCAPDALYVDTSCLT 271


                  ....*...
gi 1277644206 200 ISQILEKI 207
Cdd:PRK12269  272 IEEVCERI 279
PRK04182 PRK04182
cytidylate kinase; Provisional
 1-208 2.96e-15

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 70.61  E-value: 2.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAYARlqpdwqEVPLEDFLAsppfsfsFSKDSPlqafYGDRLL 80
Cdd:PRK04182    1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRELAKER------GMSLEEFNK-------YAEEDP----EIDKEI 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  81 TSELssQEVANfaslfsKEplvraymqtlqkqyatvGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKdlpQGSL 160
Cdd:PRK04182   64 DRRQ--LEIAE------KE-----------------DNVVLEGRLAGWMAKDYADLKIWLKAPLEVRAERIAE---REGI 115

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1277644206 161 SKEALMAELIARDQADQQR-------ECDPLVIpQDaIVIDSSNLTISQILEKIL 208
Cdd:PRK04182  116 SVEEALEETIEREESEAKRykeyygiDIDDLSI-YD-LVINTSRWDPEGVFDIIL 168
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
1-208 4.10e-15

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 70.62  E-value: 4.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNtGAMYRTLAYARlqpdwqEVPLEDFlasppfsfsfskdsplqafygdrll 80
Cdd:COG1102     1 MVITISREPGSGGTTIAKRLAEKLGLPLYD-GEILREAAKER------GLSEEEF------------------------- 48

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  81 tSELSSQEVANFASLFSKEPLVRAYMQTLQKQYATVGNCVFEGR--DMGSKVFPHAeVKIFLTAKPEIRAERRLKDLpqg 158
Cdd:COG1102    49 -EKLDEKAPSLLYRDTAEEDEIDRALDKVIRELARKGNCVIVGRlaDWILRDRPNV-LKVFLTAPLEVRVKRIAERE--- 123

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1277644206 159 SLSKEALMAELIARDQADQQR-----ECDplviPQDA----IVIDSSNLTISQILEKIL 208
Cdd:COG1102   124 GISEEEAEKEIKKRDKSRAKYykyyyGID----WGDPsnydLVINTSRLGIEEAVDLIL 178
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 1-203 2.87e-13

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 65.14  E-value: 2.87e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQFLYCNTGAMYRTLAyarlqpdwqevpledflasppfsfsfskdsplqafyGDRLL 80
Cdd:TIGR02173   1 MIITISGPPGSGKTTVAKILAEKLSLKLISAGDIFRELA------------------------------------AKMGL 44

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  81 TselssqeVANFASLFSKEPLVRAYMQTLQKQYA-TVGNCVFEGRDMGSKVFPHAEVKIFLTAKPEIRAERRLKdlpQGS 159
Cdd:TIGR02173  45 D-------LIEFLNYAEENPEIDKKIDRRIHEIAlKEKNVVLESRLAGWIVREYADVKIWLKAPLEVRARRIAK---REG 114

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1277644206 160 LSKEALMAELIARDQADQQR-------ECDPLVIPQdaIVIDSSNLTISQI 203
Cdd:TIGR02173 115 KSLTVARSETIEREESEKRRylkfygiDIDDLSIYD--LVINTSNWDPNNV 163
Dck COG1428
Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism];
1-26 1.27e-05

Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism];


Pssm-ID: 441037 [Multi-domain]  Cd Length: 205  Bit Score: 44.39  E-value: 1.27e-05
                          10        20
                  ....*....|....*....|....*.
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQF 26
Cdd:COG1428     4 RYIAVEGNIGAGKTTLARLLAEHLGA 29
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 2-27 1.61e-05

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 41.55  E-value: 1.61e-05
                          10        20
                  ....*....|....*....|....*.
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFL 27
Cdd:cd02019     1 IIAITGGSGSGKSTVAKKLAEQLGGR 26
Udk COG0572
Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway ...
 1-24 3.02e-05

Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 440337 [Multi-domain]  Cd Length: 206  Bit Score: 43.29  E-value: 3.02e-05
                          10        20
                  ....*....|....*....|....
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTL 24
Cdd:COG0572     8 RIIGIAGPSGSGKTTFARRLAEQL 31
PRK06547 PRK06547
hypothetical protein; Provisional
 1-26 4.65e-05

hypothetical protein; Provisional


Pssm-ID: 235825  Cd Length: 172  Bit Score: 42.42  E-value: 4.65e-05
                          10        20
                  ....*....|....*....|....*.
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQF 26
Cdd:PRK06547   16 ITVLIDGRSGSGKTTLAGALAARTGF 41
dNK cd01673
Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to ...
 2-28 1.08e-04

Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1.113), adenosine (EC 2.7.1.76), and thymidine (EC 2.7.1.21) kinases. They are key enzymes in the salvage of deoxyribonucleosides originating from extra- or intracellular breakdown of DNA.


Pssm-ID: 238836  Cd Length: 193  Bit Score: 41.44  E-value: 1.08e-04
                          10        20
                  ....*....|....*....|....*..
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLY 28
Cdd:cd01673     1 VIVVEGNIGAGKSTLAKELAEHLGYEV 27
NDUO42 cd02030
NADH:Ubiquinone oxioreductase, 42 kDa (NDUO42) is a family of proteins that are highly similar ...
 2-28 3.61e-04

NADH:Ubiquinone oxioreductase, 42 kDa (NDUO42) is a family of proteins that are highly similar to deoxyribonucleoside kinases (dNK). Members of this family have been identified as one of the subunits of NADH:Ubiquinone oxioreductase (complex I), a multi-protein complex located in the inner mitochondrial membrane. The main function of the complex is to transport electrons from NADH to ubiquinone, which is accompanied by the translocation of protons from the mitochondrial matrix to the inter membrane space.


Pssm-ID: 238988  Cd Length: 219  Bit Score: 40.03  E-value: 3.61e-04
                          10        20
                  ....*....|....*....|....*..
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLY 28
Cdd:cd02030     1 VITVDGNIASGKGKLAKELAEKLGMKY 27
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 1-26 4.37e-04

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 39.93  E-value: 4.37e-04
                          10        20
                  ....*....|....*....|....*.
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQF 26
Cdd:COG2074     7 RIILIGGASGVGKSTIAAELARRLGI 32
Tmk COG0125
Thymidylate kinase [Nucleotide transport and metabolism]; Thymidylate kinase is part of the ...
 1-25 5.19e-04

Thymidylate kinase [Nucleotide transport and metabolism]; Thymidylate kinase is part of the Pathway/BioSystem: Thymidylate biosynthesis


Pssm-ID: 439895 [Multi-domain]  Cd Length: 206  Bit Score: 39.76  E-value: 5.19e-04
                          10        20
                  ....*....|....*....|....*
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQ 25
Cdd:COG0125     4 KFIVFEGIDGSGKSTQIKLLAEYLE 28
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 2-44 6.50e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 38.89  E-value: 6.50e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1277644206    2 IITIDGPSGTGKSTLAKALAQTLQ-----FLYCNTGAMYRTLAYARLQ 44
Cdd:smart00382   4 VILIVGPPGSGKTTLARALARELGppgggVIYIDGEDILEEVLDQLLL 51
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
7-28 7.88e-04

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 38.74  E-value: 7.88e-04
                          10        20
                  ....*....|....*....|..
gi 1277644206   7 GPSGTGKSTLAKALAQTLQFLY 28
Cdd:COG0645     6 GLPGSGKSTLARALAERLGAVR 27
TMPK cd01672
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ...
 1-25 9.05e-04

Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).


Pssm-ID: 238835  Cd Length: 200  Bit Score: 38.79  E-value: 9.05e-04
                          10        20
                  ....*....|....*....|....*
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQ 25
Cdd:cd01672     1 MFIVFEGIDGAGKTTLIELLAERLE 25
AAA_18 pfam13238
AAA domain;
3-171 9.44e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.79  E-value: 9.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206   3 ITIDGPSGTGKSTLAKALAQTLQFlycntGAMYRTLAYARLQPDWQEVPLEDFLAsppfsfsfsKDSPLQAFYGDRLLTS 82
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGF-----GDNVRDLALENGLVLGDDPETRESKR---------LDEDKLDRLLDLLEEN 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1277644206  83 ELSSQEvanfaslfskeplvraymqtlqkqyatvGNCVFEGRdmGSKVFPHAE---VKIFLTAKPEIRAERRLKDLPQGS 159
Cdd:pfam13238  67 AALEEG----------------------------GNLIIDGH--LAELEPERAkdlVGIVLRASPEELLERLEKRGYEEA 116

                         170
                  ....*....|..
gi 1277644206 160 LSKEALMAELIA 171
Cdd:pfam13238 117 KIKENEEAEILG 128
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 7-43 9.83e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 38.28  E-value: 9.83e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1277644206   7 GPSGTGKSTLAKALAQTLQ-----FLYCNTGAMYRTLAYARL 43
Cdd:cd00009    26 GPPGTGKTTLARAIANELFrpgapFLYLNASDLLEGLVVAEL 67
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 2-25 1.06e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 38.00  E-value: 1.06e-03
                          10        20
                  ....*....|....*....|....
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQ 25
Cdd:cd02021     1 IIVVMGVSGSGKSTVGKALAERLG 24
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 7-25 1.55e-03

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 38.74  E-value: 1.55e-03
                          10
                  ....*....|....*....
gi 1277644206   7 GPSGTGKSTLAKALAQTLQ 25
Cdd:COG0464   198 GPPGTGKTLLARALAGELG 216
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 7-26 1.59e-03

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 37.19  E-value: 1.59e-03
                          10        20
                  ....*....|....*....|
gi 1277644206   7 GPSGTGKSTLAKALAQTLQF 26
Cdd:pfam00004   5 GPPGTGKTTLAKAVAKELGA 24
GMPK cd00071
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), ...
 2-20 2.63e-03

Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine diphosphate (GDP). It plays an essential role in the biosynthesis of guanosine triphosphate (GTP). This enzyme is also important for the activation of some antiviral and anticancer agents, such as acyclovir, ganciclovir, carbovir, and thiopurines.


Pssm-ID: 238026  Cd Length: 137  Bit Score: 36.74  E-value: 2.63e-03
                          10
                  ....*....|....*....
gi 1277644206   2 IITIDGPSGTGKSTLAKAL 20
Cdd:cd00071     1 LIVLSGPSGVGKSTLLKRL 19
PRK07261 PRK07261
DNA topology modulation protein;
1-57 3.25e-03

DNA topology modulation protein;


Pssm-ID: 180911 [Multi-domain]  Cd Length: 171  Bit Score: 37.00  E-value: 3.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQT--LQFLYCNTgamyrtlayARLQPDWQEVPLEDFLA 57
Cdd:PRK07261    1 MKIAIIGYSGSGKSTLARKLSQHynCPVLHLDT---------LHFQPNWQERDDDDMIA 50
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
2-21 4.49e-03

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 36.72  E-value: 4.49e-03
                          10        20
                  ....*....|....*....|
gi 1277644206   2 IITIDGPSGTGKSTLAKALA 21
Cdd:COG4619    28 CVAITGPSGSGKSTLLRALA 47
NadR3 COG3172
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase ...
 1-25 4.50e-03

Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 442405 [Multi-domain]  Cd Length: 178  Bit Score: 36.72  E-value: 4.50e-03
                          10        20
                  ....*....|....*....|....*
gi 1277644206   1 MIITIDGPSGTGKSTLAKALAQTLQ 25
Cdd:COG3172     9 KKIVLLGAESTGKTTLARALAAHYN 33
gmk PRK00300
guanylate kinase; Provisional
 2-28 6.29e-03

guanylate kinase; Provisional


Pssm-ID: 234719  Cd Length: 205  Bit Score: 36.22  E-value: 6.29e-03
                          10        20
                  ....*....|....*....|....*..
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQFLY 28
Cdd:PRK00300    7 LIVLSGPSGAGKSTLVKALLERDPNLQ 33
AAA_22 pfam13401
AAA domain;
2-25 7.00e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 35.40  E-value: 7.00e-03
                          10        20
                  ....*....|....*....|....
gi 1277644206   2 IITIDGPSGTGKSTLAKALAQTLQ 25
Cdd:pfam13401   7 ILVLTGESGTGKTTLLRRLLEQLP 30
guanyl_kin TIGR03263
guanylate kinase; Members of this family are the enzyme guanylate kinase, also called GMP ...
 2-20 7.16e-03

guanylate kinase; Members of this family are the enzyme guanylate kinase, also called GMP kinase. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 213788  Cd Length: 179  Bit Score: 35.93  E-value: 7.16e-03
                          10
                  ....*....|....*....
gi 1277644206   2 IITIDGPSGTGKSTLAKAL 20
Cdd:TIGR03263   2 LIVISGPSGAGKSTLVKAL 20
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
7-32 7.36e-03

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 36.71  E-value: 7.36e-03
                          10        20
                  ....*....|....*....|....*.
gi 1277644206   7 GPSGTGKSTLAKALAQTLQflyCNTG 32
Cdd:COG2812    39 GPRGVGKTTLARILAKALN---CENG 61
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 7-31 7.60e-03

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 36.22  E-value: 7.60e-03
                          10        20
                  ....*....|....*....|....*
gi 1277644206   7 GPSGTGKSTLAKALAQTLQFLYCNT 31
Cdd:COG0529    23 GLSGSGKSTLANALERRLFERGRHV 47
Gmk COG0194
Guanylate kinase [Nucleotide transport and metabolism];
2-20 8.28e-03

Guanylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 439964  Cd Length: 190  Bit Score: 35.81  E-value: 8.28e-03
                          10
                  ....*....|....*....
gi 1277644206   2 IITIDGPSGTGKSTLAKAL 20
Cdd:COG0194     4 LIVLSGPSGAGKTTLVKAL 22
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 7-25 9.28e-03

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 36.60  E-value: 9.28e-03
                          10
                  ....*....|....*....
gi 1277644206   7 GPSGTGKSTLAKALAQTLQ 25
Cdd:PRK13342   43 GPPGTGKTTLARIIAGATD 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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