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Conserved domains on  [gi|1266953639|gb|ATM16712|]
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DNA polymerase III subunit delta' [Raoultella planticola]

Protein Classification

DNA polymerase III subunit delta'( domain architecture ID 11483015)

DNA polymerase III subunit delta' interacts with the delta and gamma subunits and is part of the clamp-loading complex, which assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 1-334 0e+00

DNA polymerase III subunit delta'; Validated


:

Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 552.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   1 MKWYPWLRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLA 80
Cdd:PRK07993    1 MKWYPWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 PEKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK07993   81 PEKGKSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 161 LHHLAPPSESYGLAWLEREVTMPQETLLSALRLSANAPAAALDLLQESHWASRQQLTQTLAGVLSSGDWLALLPILNHEQ 240
Cdd:PRK07993  161 LHYLAPPPEQYALTWLSREVTMSQDALLAALRLSAGAPGAALALLQPERWQQREALCQALAYALPSGDWLSLLPALNHEQ 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 241 AAVRLHWLASLLLDAQKRQQGITLVSNPDAWTLVNQLAQALPAARLQAIARDVSACRDQLLNVVGVNRELLLTERLLRWE 320
Cdd:PRK07993  241 APARLHWLATLLMDALKRQHGAAYVTNQDQPPLVAQLANHLSPARLQAILGDVCHCREQLLSVTGVNRELLLTDLLLRIE 320

                         330
                  ....*....|....
gi 1266953639 321 HYLQPGTVLPVSHL 334
Cdd:PRK07993  321 HYLQPGTVLPVPHL 334
 
Name Accession Description Interval E-value
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 1-334 0e+00

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 552.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   1 MKWYPWLRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLA 80
Cdd:PRK07993    1 MKWYPWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 PEKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK07993   81 PEKGKSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 161 LHHLAPPSESYGLAWLEREVTMPQETLLSALRLSANAPAAALDLLQESHWASRQQLTQTLAGVLSSGDWLALLPILNHEQ 240
Cdd:PRK07993  161 LHYLAPPPEQYALTWLSREVTMSQDALLAALRLSAGAPGAALALLQPERWQQREALCQALAYALPSGDWLSLLPALNHEQ 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 241 AAVRLHWLASLLLDAQKRQQGITLVSNPDAWTLVNQLAQALPAARLQAIARDVSACRDQLLNVVGVNRELLLTERLLRWE 320
Cdd:PRK07993  241 APARLHWLATLLMDALKRQHGAAYVTNQDQPPLVAQLANHLSPARLQAILGDVCHCREQLLSVTGVNRELLLTDLLLRIE 320

                         330
                  ....*....|....
gi 1266953639 321 HYLQPGTVLPVSHL 334
Cdd:PRK07993  321 HYLQPGTVLPVPHL 334
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
7-302 1.43e-75

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 234.10  E-value: 1.43e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   7 LRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHScQLMQAGTHPDYYTLAPEKGKS 86
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCHS-RLMAAGNHPDLLELNPEEKSD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  87 ALGIDAVRDVNEKLYERSRLGGAKVVW-------------AGdaalltdaaanalLKTLEEPPENTWFFLACQEPARLLA 153
Cdd:COG0470    80 QIGIDQIRELGEFLSLTPLEGGRKVVIideadamneaaanAL-------------LKTLEEPPKNTPFILIANDPSRLLP 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 154 TLRSRCRLHHLAPPSESYGLAWLEREvTMPQETLLSALRLSANAPAAALDLLQEshWASRQQLTQTLAGVLSSGDWLALL 233
Cdd:COG0470   147 TIRSRCQVIRFRPPSEEEALAWLREE-GVDEDALEAILRLAGGDPRAAINLLQA--LAGRKELLEDLAALLSRDRALELL 223

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1266953639 234 PILNHEQAAVRLHWLASLLLDAqkrqqgitlvsnpdawtlvnqLAQALPAARLQAIARDVSACRDQLLN 302
Cdd:COG0470   224 DALLKAEALELLDWLLKWLLDN---------------------LPLEYAGEDLARAYEALSEADRRLGR 271
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-201 4.54e-56

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 180.52  E-value: 4.54e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  11 FEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKGKsaLGI 90
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQS--IKV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  91 DAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSES 170
Cdd:TIGR00678  79 DQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEE 158

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1266953639 171 YGLAWLEREvTMPQETLLSALRLSANAPAAA 201
Cdd:TIGR00678 159 ALLQWLIRQ-GISEEAAELLLALAGGSPGRA 188
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 11-168 2.04e-31

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 115.77  E-value: 2.04e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  11 FEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKGksALGI 90
Cdd:pfam13177   6 IQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQ--SIKI 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1266953639  91 DAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPS 168
Cdd:pfam13177  84 DQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPLS 161
 
Name Accession Description Interval E-value
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 1-334 0e+00

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 552.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   1 MKWYPWLRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLA 80
Cdd:PRK07993    1 MKWYPWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 PEKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK07993   81 PEKGKSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 161 LHHLAPPSESYGLAWLEREVTMPQETLLSALRLSANAPAAALDLLQESHWASRQQLTQTLAGVLSSGDWLALLPILNHEQ 240
Cdd:PRK07993  161 LHYLAPPPEQYALTWLSREVTMSQDALLAALRLSAGAPGAALALLQPERWQQREALCQALAYALPSGDWLSLLPALNHEQ 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 241 AAVRLHWLASLLLDAQKRQQGITLVSNPDAWTLVNQLAQALPAARLQAIARDVSACRDQLLNVVGVNRELLLTERLLRWE 320
Cdd:PRK07993  241 APARLHWLATLLMDALKRQHGAAYVTNQDQPPLVAQLANHLSPARLQAILGDVCHCREQLLSVTGVNRELLLTDLLLRIE 320

                         330
                  ....*....|....
gi 1266953639 321 HYLQPGTVLPVSHL 334
Cdd:PRK07993  321 HYLQPGTVLPVPHL 334
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 1-307 1.95e-76

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 237.33  E-value: 1.95e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   1 MKWYPWLRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLA 80
Cdd:PRK06871    1 MALYPWLQPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 PEKGKSaLGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK06871   81 PIDNKD-IGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 161 LHHLAPPSESYGLAWLEREVTMPQETLLSALRLSANAPAAALDLLQESHWASRQQLTQTLAGVLSSGDWLALLPILNHEQ 240
Cdd:PRK06871  160 TWLIHPPEEQQALDWLQAQSSAEISEILTALRINYGRPLLALTFLEQGLLEQRKTFLRQFWLFYRRRSPLELLPLFDKEL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1266953639 241 AAVRLHWLASLLLDAQKRQQGITL-VSNPDAWTLVNQLAQALPAARLQAIARDVSACRDQLLNVVGVN 307
Cdd:PRK06871  240 VLQQLDWLLAFLSDALKAKLDIASgWICQDLQRGILQFSQQQSAQGLLKAHQIIQKVRSDLLQINAVN 307
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
7-302 1.43e-75

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 234.10  E-value: 1.43e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   7 LRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHScQLMQAGTHPDYYTLAPEKGKS 86
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCHS-RLMAAGNHPDLLELNPEEKSD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  87 ALGIDAVRDVNEKLYERSRLGGAKVVW-------------AGdaalltdaaanalLKTLEEPPENTWFFLACQEPARLLA 153
Cdd:COG0470    80 QIGIDQIRELGEFLSLTPLEGGRKVVIideadamneaaanAL-------------LKTLEEPPKNTPFILIANDPSRLLP 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 154 TLRSRCRLHHLAPPSESYGLAWLEREvTMPQETLLSALRLSANAPAAALDLLQEshWASRQQLTQTLAGVLSSGDWLALL 233
Cdd:COG0470   147 TIRSRCQVIRFRPPSEEEALAWLREE-GVDEDALEAILRLAGGDPRAAINLLQA--LAGRKELLEDLAALLSRDRALELL 223

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1266953639 234 PILNHEQAAVRLHWLASLLLDAqkrqqgitlvsnpdawtlvnqLAQALPAARLQAIARDVSACRDQLLN 302
Cdd:COG0470   224 DALLKAEALELLDWLLKWLLDN---------------------LPLEYAGEDLARAYEALSEADRRLGR 271
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-201 4.54e-56

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 180.52  E-value: 4.54e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  11 FEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKGKsaLGI 90
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQS--IKV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  91 DAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSES 170
Cdd:TIGR00678  79 DQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEE 158

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1266953639 171 YGLAWLEREvTMPQETLLSALRLSANAPAAA 201
Cdd:TIGR00678 159 ALLQWLIRQ-GISEEAAELLLALAGGSPGRA 188
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 4-307 1.23e-45

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 157.94  E-value: 1.23e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   4 YPWLRPSFEQLVAgyqAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEK 83
Cdd:PRK05707    5 YPWQQSLWQQLAG---RGRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLEPEE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  84 GKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHH 163
Cdd:PRK05707   82 ADKTIKVDQVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 164 LAPPSESYGLAWLEREVT-MPQETLLSALRLSANAPAAALDLLQESHWASRQQLTQTLAGVLSS-GDWLALLPILNHEQA 241
Cdd:PRK05707  162 CPLPSNEESLQWLQQALPeSDERERIELLTLAGGSPLRALQLHEQGVREQRARVLDGVKKLLKQqQSASQLAESWLKVPL 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1266953639 242 AVRLHW---LASLLLDAQKRQQGITLVsNPDAWTLVNQLAQALPAARLQAIARDVSACRDQLLNVVGVN 307
Cdd:PRK05707  242 LLLFDWfcdWAHDILRYQLTQDEEGLG-LADMRKVLQYLAQKSPQAKVLALQDWLLEQRQKVLGKANLN 309
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
 4-262 1.94e-44

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 154.58  E-value: 1.94e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   4 YPWLRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEgNKSCGQCHSCQLMQAGTHPDYYTLAPEK 83
Cdd:PRK06090    5 YPWLVPVWQNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQ-SEACGFCHSCELMQSGNHPDLHVIKPEK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  84 GKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHH 163
Cdd:PRK06090   84 EGKSITVEQIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWV 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 164 LAPPSESYGLAWLERE-VTMPQetllSALRLSANAPAAALDLLQESHWASRQQLTQTLAGVLSS--GDWLALLPILNhEQ 240
Cdd:PRK06090  164 VTPPSTAQAMQWLKGQgITVPA----YALKLNMGSPLKTLAMMKEGGLEKYHKLERQLVDALSGpvSDQLKCASLIA-AD 238

                         250       260
                  ....*....|....*....|..
gi 1266953639 241 AAVRLHWLASLLLDAQKRQQGI 262
Cdd:PRK06090  239 PLTHLSWLWLLLTDAQKVHFGV 260
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
12-300 7.49e-37

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 134.93  E-value: 7.49e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  12 EQLVAGYQAGRGHHALLLQALPGMGGE--ALIYAlcRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKgkSALG 89
Cdd:COG2812    20 RTLKNALASGRLAHAYLFTGPRGVGKTtlARILA--KALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEA--SNIG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  90 IDAVRDVNEKLYERSRLGGAKVVwagdaalltdaaanallKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSE 169
Cdd:COG2812    96 VDDIRELIEKVSYAPVEGRYKVYiideahmltteafnallKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPP 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 170 SYGLAWLER-----EVTMPQETLLSALRLSANAPAAALDLLQE---SHWASRQQLTQTLAGVLSSGDWLALLPILN---- 237
Cdd:COG2812   176 EEIAEHLAKiaereGIEIEPEALALIARAADGSMRDALSLLDQaiaFGLLDRRELLLDLLEALLAGDVAALLALAEelak 255

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1266953639 238 --HEQAAVrLHWLASLLLDAQKRQQGIT--LVSNPDAWTLVNQLAQALPAARLQAIARDVSACRDQL 300
Cdd:COG2812   256 rgRDLKRF-LDDLLSLLRDLLLLKLGPDaeLLVNEDERERLQELARRLSPERLLRAIQILLEARREL 321
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
 4-304 4.65e-33

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 124.60  E-value: 4.65e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   4 YPWLRPSFEQLVAGYQagRGHHALLLQALPGMGGEALIYALCRYLMCRQP-EGNKSCGQCHSCQLMQAGTHPDYYTLAP- 81
Cdd:PRK08699    3 YPWHQEQWRQIAEHWE--RRPNAWLFAGKKGIGKTAFARFAAQALLCETPaPGHKPCGECMSCHLFGQGSHPDFYEITPl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  82 ----EKGKSAL--GIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATL 155
Cdd:PRK08699   81 sdepENGRKLLqiKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 156 RSRCRLHHLAPPSESYGLAWL-EREVTMPQETLlsalrlsANAPAAALDLLQESHWASRQQLTQTLAGVlSSGDWLALLP 234
Cdd:PRK08699  161 KSRCRKMVLPAPSHEEALAYLrERGVAEPEERL-------AFHSGAPLFDEEPELRALRIKLLDILAEP-RLLKILDYAA 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1266953639 235 ILNHEQ--AAVRLHWLASLLLDAQKRQQGITLVSNPDAwtlVNQLAQALPAARlqaiARDVSACRDQLLNVV 304
Cdd:PRK08699  233 LFDKEKlpLAVFVGWMQKWLVDLGLCLQHMKPVYYPAY---EDRLLQTASGFR----PRNVFAAEDMLKQLA 297
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 11-168 2.04e-31

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 115.77  E-value: 2.04e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  11 FEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKGksALGI 90
Cdd:pfam13177   6 IQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQ--SIKI 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1266953639  91 DAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPS 168
Cdd:pfam13177  84 DQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPLS 161
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
 4-297 7.53e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 108.31  E-value: 7.53e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   4 YPWLRPSFEQLvagyQAGRGH--HALLLQALPGMGGEALIYALCRYLMCRQPEGN-KSCGQCHSCQLMQAGTHPDYYTLA 80
Cdd:PRK06964    3 YPWQTDDWNRL----QALRARlpHALLLHGQAGIGKLDFAQHLAQGLLCETPQPDgEPCGTCAACNWFAQGNHPDYRIVR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 PE--------------------KGKSA------LGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEE 134
Cdd:PRK06964   79 PEalaaeapgaadeakeadadeGGKKTkapskeIKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 135 PPENTWFFLACQEPARLLATLRSRCRLHHLAPPSESYGLAWLEREVTMPQETLLSalrLSANAPAAALDLLQESHWASRQ 214
Cdd:PRK06964  159 PPPGTVFLLVSARIDRLLPTILSRCRQFPMTVPAPEAAAAWLAAQGVADADALLA---EAGGAPLAALALASDENRPLRD 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 215 QLTQTLA-----GVLSSGDWLALLPIlnheqaAVRLHWLASLLLDAQKRQQGITLVSNPDAWTLVNQLAQALPAARLQAI 289
Cdd:PRK06964  236 WTLGQLAagaacDAFACAETLQKLPV------PAVLGWLQRWLYDLLAQRLAGAPRYFPAQRAALARCAAAVDANALARF 309


                  ....*...
gi 1266953639 290 ARDVSACR 297
Cdd:PRK06964  310 AKAVTRQR 317
DNApol3-delta_C pfam09115
DNA polymerase III, delta subunit, C terminal; Members of this family, which are predominantly ...
 210-319 4.00e-23

DNA polymerase III, delta subunit, C terminal; Members of this family, which are predominantly found in prokaryotic DNA polymerase III, assume an alpha helical structure, with a core of five alpha helices, and an additional small helix. They are essential for the formation of the polymerase clamp loader.


Pssm-ID: 430418 [Multi-domain]  Cd Length: 112  Bit Score: 92.31  E-value: 4.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 210 WASRQQLTQTL-AGVLSSGDWLALLPILNHEQAAVRLHWLASLLLDAQKRQQGITL-VSNPDAWTLVNQLAQALPAARLQ 287
Cdd:pfam09115   1 WQARKALLQALvALALQRGDLLSLLPLLNKDDALVRLHWLSSLLLDALKYQQGVQDqLVNQDQIALIAQLAQRLSAERLL 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1266953639 288 AIARDVSACRDQLLNVVGVNRELLLTERLLRW 319
Cdd:pfam09115  81 AQLQKLLECREQLLSIPGVNRELLLTEWLLRW 112
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
 5-253 5.22e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 97.34  E-value: 5.22e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   5 PWLRPSFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEgnkSCGQCHSCQLMQAGTHPDYYTLA---- 80
Cdd:PRK08769    7 PWQQRAYDQTVAALDAGRLGHGLLICGPEGLGKRAVALALAEHVLASGPD---PAAAQRTRQLIAAGTHPDLQLVSfipn 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 --PEKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSR 158
Cdd:PRK08769   84 rtGDKLRTEIVIEQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 159 C-RLHHLAPPSESyGLAWLEREvTMPQETLLSALRLSANAPAAALDLLQESHWASRQQLTQTLAGvLSSGDWLAL---LP 234
Cdd:PRK08769  164 CqRLEFKLPPAHE-ALAWLLAQ-GVSERAAQEALDAARGHPGLAAQWLREDGLALRRAVAQDLEQ-IASGRAGAVdvaQR 240

                         250
                  ....*....|....*....
gi 1266953639 235 ILNHEQAAVRLHWLASLLL 253
Cdd:PRK08769  241 WTNDGQADQRLRHAADLAL 259
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
 14-222 4.43e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 83.92  E-value: 4.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  14 LVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQC----------HSCQLMQAGTHPDYYTL---A 80
Cdd:PRK07471   31 LLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLLATPPPGGDGAVPPptslaidpdhPVARRIAAGAHGGLLTLersW 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 PEKG---KSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRS 157
Cdd:PRK07471  111 NEKGkrlRTVITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRS 190

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1266953639 158 RCRLHHLAPPSESYGLAWLEREVTMPQETLLSAL-RLSANAPAAALDLLQESHWASRQQLTQTLAG 222
Cdd:PRK07471  191 RCRKLRLRPLAPEDVIDALAAAGPDLPDDPRAALaALAEGSVGRALRLAGGDGLALYRRLTALLDT 256
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
 12-194 3.43e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 81.50  E-value: 3.43e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  12 EQLVAGYQAGRGH---------HALLLQALPGMGGEALIYALCRYLMCRQPeGNKSCGQCHSCQLMQAGTHPDYYTLAPE 82
Cdd:PRK07940   15 AELRAAARAARADvaaagsgmtHAWLFTGPPGSGRSVAARAFAAALQCTDP-DEPGCGECRACRTVLAGTHPDVRVVAPE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  83 KgkSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLH 162
Cdd:PRK07940   94 G--LSIGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHV 171

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1266953639 163 HLAPPSESYGLAWLEREVTMPQETLLSALRLS 194
Cdd:PRK07940  172 ALRTPSVEAVAEVLVRRDGVDPETARRAARAS 203
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 21-265 1.98e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 75.73  E-value: 1.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEkGKSaLGIDAVRDVNEKL 100
Cdd:PRK08058   25 NRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVAPD-GQS-IKKDQIRYLKEEF 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 101 YERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAP-PSESYGLAWLERE 179
Cdd:PRK08058  103 SKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPlPPESLIQRLQEEG 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 180 VTMPQETLLSALrlsANAPAAALDLLQESHWASRQQLTQTLAGVLSSGDWLALLPIlnHEQaavrlhWLAsLLLDAQKRQ 259
Cdd:PRK08058  183 ISESLATLLAGL---TNSVEEALALSEDDWFAQARALVIKLYEALHEKDLQSFVFV--QEK------WMP-LFKEKDQQQ 250


                  ....*.
gi 1266953639 260 QGITLV 265
Cdd:PRK08058  251 LGLDLL 256
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 2-159 6.16e-15

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 75.52  E-value: 6.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   2 KWYPwlrPSFEQLVA----------GYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAG 71
Cdd:PRK08691    9 KWRP---KTFADLVGqehvvkalqnALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  72 THPDyytLAPEKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARL 151
Cdd:PRK08691   86 RYVD---LLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKV 162


                  ....*...
gi 1266953639 152 LATLRSRC 159
Cdd:PRK08691  163 PVTVLSRC 170
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
 12-160 1.36e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 74.49  E-value: 1.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  12 EQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCrQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKGKSalgID 91
Cdd:PRK14963   24 EVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGECESCLAVRRGAHPDVLEIDAASNNS---VE 99

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1266953639  92 AVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK14963  100 DVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQ 168
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
 8-178 1.80e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 74.09  E-value: 1.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   8 RPSFEQLVAGYQA-----------GRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDY 76
Cdd:PRK14953   11 RPKFFKEVIGQEIvvrilknavklQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  77 YTLapeKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLR 156
Cdd:PRK14953   91 IEI---DAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTIL 167

                         170       180
                  ....*....|....*....|..
gi 1266953639 157 SRCRLHHLAPPSESYGLAWLER 178
Cdd:PRK14953  168 SRCQRFIFSKPTKEQIKEYLKR 189
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
 22-202 1.86e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 70.57  E-value: 1.86e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  22 RGHHALLLQALPGMGGEALIYALCRYLMCRQP-EGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNEK- 99
Cdd:PRK06305   37 RAAHAYLFSGIRGTGKTTLARIFAKALNCQNPtEDQEPCNQCASCKEISSGTSLDVLEI---DGASHRGIEDIRQINETv 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 100 LYERSRlGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSESyglAWLERE 179
Cdd:PRK06305  114 LFTPSK-SRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKMHLKRIPEE---TIIDKL 189

                         170       180
                  ....*....|....*....|....*..
gi 1266953639 180 VTMPQ----ETLLSALRLSANAPAAAL 202
Cdd:PRK06305  190 ALIAKqegiETSREALLPIARAAQGSL 216
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 25-161 1.35e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 68.25  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  25 HALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNEKLYERS 104
Cdd:PRK14962   37 HAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMDVIEL---DAASNRGIDEIRKIRDAVGYRP 113

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1266953639 105 RLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRL 161
Cdd:PRK14962  114 MEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQV 170
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
 14-166 9.87e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 65.06  E-value: 9.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  14 LVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCR-----------QPEGNKSCGQchscQLMQaGTHPDYYTLA-- 80
Cdd:PRK09112   35 LAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILSHpdpaeapetlaDPDPASPVWR----QIAQ-GAHPNLLHITrp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  81 ----PEKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLR 156
Cdd:PRK09112  110 fdekTGKFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIR 189

                         170
                  ....*....|
gi 1266953639 157 SRCRLHHLAP 166
Cdd:PRK09112  190 SRCQPISLKP 199
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
 21-159 1.66e-11

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 64.51  E-value: 1.66e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGE--ALIYALCryLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNE 98
Cdd:TIGR02397  33 GRIAHAYLFSGPRGTGKTsiARIFAKA--LNCQNGPDGEPCNECESCKEINSGSSLDVIEI---DAASNNGVDDIREILD 107

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1266953639  99 KLYERSRLGGAKV------------VWagdaalltdaaaNALLKTLEEPPENTWFFLACQEPARLLATLRSRC 159
Cdd:TIGR02397 108 NVKYAPSSGKYKVyiidevhmlsksAF------------NALLKTLEEPPEHVVFILATTEPHKIPATILSRC 168
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
 2-304 8.15e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 62.84  E-value: 8.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   2 KWYPwlrPSFEQLVA----------GYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAG 71
Cdd:PRK14969    9 KWRP---KSFSELVGqehvvraltnALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEIDSG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  72 THPDYYTLapeKGKSALGIDAVRDVNEK-LYERSRlGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPAR 150
Cdd:PRK14969   86 RFVDLIEV---DAASNTQVDAMRELLDNaQYAPTR-GRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 151 LLATLRSRC---RLHHLAPPSESYGLAWLEREVTMPQETllSALRLSANAPAA----ALDLLQE--SHWASR--QQLTQT 219
Cdd:PRK14969  162 IPVTVLSRClqfNLKQMPPPLIVSHLQHILEQENIPFDA--TALQLLARAAAGsmrdALSLLDQaiAYGGGTvnESEVRA 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 220 LAGVLSSGDWLALLPILnHEQAAvrlhwlASLLldAQKRQQGITLVSNPDAW----TLVNQL--AQALPaarlQAIARDV 293
Cdd:PRK14969  240 MLGAIDQDYLFALLEAL-LAQDG------AALL--AIADAMEERSLSFDAALqdlaALLHRLaiAQTVP----DSIADDL 306

                         330
                  ....*....|.
gi 1266953639 294 SAcRDQLLNVV 304
Cdd:PRK14969  307 PE-RDRLLDLA 316
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
 18-164 9.38e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 62.66  E-value: 9.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  18 YQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVN 97
Cdd:PRK14956   34 LKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSDVLEI---DAASNRGIENIRELR 110

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1266953639  98 EKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHL 164
Cdd:PRK14956  111 DNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDFIF 177
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
 17-169 4.75e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 60.21  E-value: 4.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  17 GYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDV 96
Cdd:PRK14961   31 GLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKGLCLDLIEI---DAASRTKVEEMREI 107

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1266953639  97 NEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSE 169
Cdd:PRK14961  108 LDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQFKLKIISE 180
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
 24-287 5.23e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 60.51  E-value: 5.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  24 HHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNEKLYER 103
Cdd:PRK14958   38 HHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEV---DAASRTKVEDTRELLDNIPYA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 104 SRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLA--PPSE--SYGLAWLERE 179
Cdd:PRK14958  115 PTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRCLQFHLAqlPPLQiaAHCQHLLKEE 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 180 VTMPQETLLSALRLSANAPAA-ALDLLQES-HWASRQQLTQTLAGVLSSGDWLALLPILN--HEQAAVRLHWLASLLLda 255
Cdd:PRK14958  195 NVEFENAALDLLARAANGSVRdALSLLDQSiAYGNGKVLIADVKTMLGTIEPLLLFDILEalAAKAGDRLLGCVTRLV-- 272

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1266953639 256 qkrQQGITLVSN-PDAWTLVNQLA--QALPAARLQ 287
Cdd:PRK14958  273 ---EQGVDFSNAlADLLSLLHQIAiiQTVPEALIE 304
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 11-266 7.38e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 58.87  E-value: 7.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  11 FEQLVAGYQAGRGHHALLLQAlpGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLAPEKG--KSAL 88
Cdd:PRK07276   11 FQRFQTILEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQGQviKTDT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  89 GIDAVRDVNEKLYErsrlGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLaPPS 168
Cdd:PRK07276   89 IRELVKNFSQSGYE----GKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHF-PKN 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 169 ESYGLAWLERE-VTMPQETLLSALrlsANAPAAALDLLQESHWASRQQLTQTLAGVLssgdwlallpILNHEQAAVRLHW 247
Cdd:PRK07276  164 EAYLIQLLEQKgLLKTQAELLAKL---AQSTSEAEKLAQNKKFLELIDQAERFVTIL----------LKDKDEAYLQVAR 230

                         250
                  ....*....|....*....
gi 1266953639 248 LASLLLDAQKRQQGITLVS 266
Cdd:PRK07276  231 LVQLADEKEEQDQVLTLLT 249
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
 83-169 1.87e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 58.12  E-value: 1.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  83 KGKSALGIDAVRD----VNEKLYErsrlGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSR 158
Cdd:PRK05564   68 INKKSIGVDDIRNiieeVNKKPYE----GDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSR 143

                          90
                  ....*....|.
gi 1266953639 159 CRLHHLAPPSE 169
Cdd:PRK05564  144 CQIYKLNRLSK 154
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
21-159 2.63e-09

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 58.35  E-value: 2.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGN-----KSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRD 95
Cdd:PRK12323   35 QRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGEggitaQPCGQCRACTEIDAGRFVDYIEM---DAASNRGVDEMAQ 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1266953639  96 VNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRC 159
Cdd:PRK12323  112 LLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRC 175
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 22-284 4.91e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 57.42  E-value: 4.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  22 RGHHALLLQALPGMGGEALIYALCRYLMCRQPEGN-----KSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDV 96
Cdd:PRK14951   36 RLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDGQggitaTPCGVCQACRDIDSGRFVDYTEL---DAASNRGVDEVQQL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  97 NEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPpsesyglawl 176
Cdd:PRK14951  113 LEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSRCLQFNLRP---------- 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 177 erevtMPQETLLSAL-------RLSANAPAAALdLLQESHWASRQQLTQT-LAGVLSSGDWlallpilnhEQAAVRlHWL 248
Cdd:PRK14951  183 -----MAPETVLEHLtqvlaaeNVPAEPQALRL-LARAARGSMRDALSLTdQAIAFGSGQL---------QEAAVR-QML 246

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 249 ASL-------LLDAQKRQQGITLVSNPDAW---------------TLVNQLA--QALPAA 284
Cdd:PRK14951  247 GSVdrshvfrLIDALAQGDGRTVVETADELrlnglsaastleemaAVLQRMAvlQAVPQA 306
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 19-160 1.23e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 56.23  E-value: 1.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  19 QAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNE 98
Cdd:PRK14959   33 QENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDVVEI---DGASNRGIDDAKRLKE 109

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1266953639  99 KLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK14959  110 AIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQ 171
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 21-159 1.41e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 55.90  E-value: 1.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNEK- 99
Cdd:PRK14965   35 GRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITEGRSVDVFEI---DGASNTGVDDIRELRENv 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1266953639 100 --LYERSRLggaKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRC 159
Cdd:PRK14965  112 kyLPSRSRY---KIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRC 170
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
 10-170 2.10e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 55.47  E-value: 2.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  10 SFEQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDyytLAPEKGKSALG 89
Cdd:PRK14957   24 ALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNNSFID---LIEIDAASRTG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  90 IDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSE 169
Cdd:PRK14957  101 VEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLKHISQ 180


                  .
gi 1266953639 170 S 170
Cdd:PRK14957  181 A 181
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
14-166 4.28e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 54.67  E-value: 4.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  14 LVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDyytLAPEKGKSALGIDAV 93
Cdd:PRK14960   27 LSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVNEGRFID---LIEIDAASRTKVEDT 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1266953639  94 RDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAP 166
Cdd:PRK14960  104 RELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRCLQFTLRP 176
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 19-160 6.02e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 54.05  E-value: 6.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  19 QAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGN-KSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVN 97
Cdd:PRK14950   33 AEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDPKgRPCGTCEMCRAIAEGSAVDVIEM---DAASHTSVDDAREII 109

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1266953639  98 EKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK14950  110 ERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRCQ 172
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
 8-158 6.39e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 53.88  E-value: 6.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   8 RP-SFEQLVaGYQA-----------GRGHHALLLQALPGMG--GEALIYAlcRYLMCRQPEGNKSCGQCHSCQLMQAGTH 73
Cdd:PRK08451    9 RPkHFDELI-GQESvsktlslaldnNRLAHAYLFSGLRGSGktSSARIFA--RALVCEQGPSSTPCDTCIQCQSALENRH 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  74 PDYYTLapeKGKSALGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLA 153
Cdd:PRK08451   86 IDIIEM---DAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPA 162


                  ....*
gi 1266953639 154 TLRSR 158
Cdd:PRK08451  163 TILSR 167
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
 19-160 9.16e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 50.15  E-value: 9.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  19 QAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNE 98
Cdd:PRK06647   33 ESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSIDNDNSLDVIEI---DGASNTSVQDVRQIKE 109

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1266953639  99 KLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK06647  110 EIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQ 171
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
12-168 9.43e-07

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 50.26  E-value: 9.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  12 EQLVAGYQAGRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMqAGTHPDYYTLAPEKGKSALGID 91
Cdd:PRK14952   23 EPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVAL-APNGPGSIDVVELDAASHGGVD 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  92 AVRDVNEKLY---ERSRLggaKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCrlHH----L 164
Cdd:PRK14952  102 DTRELRDRAFyapAQSRY---RIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRT--HHypfrL 176


                  ....
gi 1266953639 165 APPS 168
Cdd:PRK14952  177 LPPR 180
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
130-286 2.12e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 49.19  E-value: 2.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 130 KTLEEPPENTWFFLACQEPARLLATLRSRCR------------LHHLAPPSESYGLAWLEREVTM-PQ---------ETL 187
Cdd:PRK14948  143 KTLEEPPPRVVFVLATTDPQRVLPTIISRCQrfdfrripleamVQHLSEIAEKESIEIEPEALTLvAQrsqgglrdaESL 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639 188 LSALRLSANA--PAAALDLLQEshwASRQQLTQtLAGVLSSGDWLALLPILNH------EQAAVrLHWLASLLLD----- 254
Cdd:PRK14948  223 LDQLSLLPGPitPEAVWDLLGA---VPEQDLLN-LLKALASNDPESLLDSCRQlldrgrEPLAI-LQGLAAFYRDlllak 297

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1266953639 255 -AQKRQQgITLVSnPDAWTLVNQLAQALPAARL 286
Cdd:PRK14948  298 tAPNRPD-LVAVS-QQTWDELCKLAKQINLERI 328
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
 21-164 2.63e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 48.70  E-value: 2.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQP--EGN--KSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDV 96
Cdd:PRK06645   40 DRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALitENTtiKTCEQCTNCISFNNHNHPDIIEI---DAASKTSVDDIRRI 116

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1266953639  97 NEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHL 164
Cdd:PRK06645  117 IESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQRYDL 184
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
 21-160 3.09e-06

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 48.35  E-value: 3.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQ--------PEGNKSCGQCHSCQLMQAGTHpdyYTLAPEKGKSALGIDA 92
Cdd:PRK14955   35 GRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmiddadylQEVTEPCGECESCRDFDAGTS---LNISEFDAASNNSVDD 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1266953639  93 VRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK14955  112 IRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQ 179
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 21-160 2.09e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 46.09  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQ--------PEGNKSCGQCHSCQLMQAGTHpdyYTLAPEKGKSALGIDA 92
Cdd:PRK14954   35 DRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmiddpvylQEVTEPCGECESCRDFDAGTS---LNISEFDAASNNSVDD 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1266953639  93 VRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK14954  112 IRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQ 179
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
21-197 2.46e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  21 GRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapekgksalgiDAV--RDVNE 98
Cdd:PRK07003   35 GRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDYVEM-----------DAAsnRGVDE 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  99 --KLYERSRLGGA----KVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRLHHLAPPSESYG 172
Cdd:PRK07003  104 maALLERAVYAPVdarfKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPAGHI 183

                         170       180
                  ....*....|....*....|....*...
gi 1266953639 173 LAWLER---EVTMPQEtlLSALRLSANA 197
Cdd:PRK07003  184 VSHLERilgEERIAFE--PQALRLLARA 209
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 2-159 2.67e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 45.87  E-value: 2.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   2 KWypwlRPS-FEQLV-----------AGYQAgRGHHALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQ 69
Cdd:PRK14949    9 KW----RPAtFEQMVgqshvlhaltnALTQQ-RLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCVEIA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  70 AGTHPDYytlapekgksaLGIDA-----VRDVNEKL----YERSRlGGAKVVWAGDAALLTDAAANALLKTLEEPPENTW 140
Cdd:PRK14949   84 QGRFVDL-----------IEVDAasrtkVDDTRELLdnvqYRPSR-GRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVK 151

                         170
                  ....*....|....*....
gi 1266953639 141 FFLACQEPARLLATLRSRC 159
Cdd:PRK14949  152 FLLATTDPQKLPVTVLSRC 170
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
 74-159 4.65e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 44.45  E-value: 4.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  74 PDYYTLAPEKGKSA----LGIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPA 149
Cdd:PRK06581   51 PDYHFIARETSATSnaknISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAA 130

                          90
                  ....*....|
gi 1266953639 150 RLLATLRSRC 159
Cdd:PRK06581  131 SIISTIRSRC 140
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
 130-159 5.18e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 44.86  E-value: 5.18e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 1266953639 130 KTLEEPPENTWFFLACQEPARLLATLRSRC 159
Cdd:PRK05563  141 KTLEEPPAHVIFILATTEPHKIPATILSRC 170
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
 8-159 3.18e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 42.46  E-value: 3.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639   8 RPS-FEQLVA----------GYQAGRGHHALLLQALPGMGGE--ALIYALCryLMCRQPEGNKSCGQCHSCQLMQAGTHP 74
Cdd:PRK14964    8 RPSsFKDLVGqdvlvrilrnAFTLNKIPQSILLVGASGVGKTtcARIISLC--LNCSNGPTSDPCGTCHNCISIKNSNHP 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  75 DYYTLapeKGKSALGIDAVRDVNEK---LYERSRLggaKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARL 151
Cdd:PRK14964   86 DVIEI---DAASNTSVDDIKVILENscyLPISSKF---KVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKI 159


                  ....*...
gi 1266953639 152 LATLRSRC 159
Cdd:PRK14964  160 PVTIISRC 167
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
 25-160 7.90e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 40.98  E-value: 7.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  25 HALLLQALPGMGGEALIYALCRYLMCRQPEGNKSCGQCHSCQLMQAGTHPDYYTLapeKGKSALGIDAVRDVNEKLYERS 104
Cdd:PRK05896   39 HAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTNQSVDIVEL---DAASNNGVDEIRNIIDNINYLP 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1266953639 105 RLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCR 160
Cdd:PRK05896  116 TTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQ 171
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
25-161 9.33e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 40.91  E-value: 9.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  25 HALLLQALPGMGGE--ALIYALCRYLMCRQPEGnKSCGQCHSCQLMQAGTHPDYYTLAPEKGKSalgIDAVRDVNEKLYE 102
Cdd:PRK14971   40 HAYLFCGPRGVGKTtcARIFAKTINCQNLTADG-EACNECESCVAFNEQRSYNIHELDAASNNS---VDDIRNLIEQVRI 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1266953639 103 RSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRL 161
Cdd:PRK14971  116 PPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRCQI 174
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
 73-159 1.24e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 40.16  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  73 HPDYYTLAPEkGKSAL-GIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARL 151
Cdd:PRK05917   60 HPDIHEFSPQ-GKGRLhSIETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRL 138


                  ....*...
gi 1266953639 152 LATLRSRC 159
Cdd:PRK05917  139 PPTIRSRS 146
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
 130-159 1.42e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 39.71  E-value: 1.42e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1266953639 130 KTLEEPPENTWFFLACQEPARLLATLRSRC 159
Cdd:PRK07132  112 KTIEEPPKDTYFLLTTKNINKVLPTIVSRC 141
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
 89-161 2.49e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 39.47  E-value: 2.49e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1266953639  89 GIDAVRDVNEKLYERSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRCRL 161
Cdd:PRK14970   89 SVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQI 161
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
 25-159 4.28e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 38.28  E-value: 4.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1266953639  25 HALLLQALPGMGGEALIYALCRYLMCRQpeGNKSCGQCHSCQLMQAGTHPDYYTLAPEKG--KSALGIDAVRDVNeklYE 102
Cdd:PRK05818    8 HPLLLIERKGSFLKPFLYEYLTSIVCTK--ANGFCKTCESCLKILNGKYNDFYLIFDQKNpiKKEDALSIINKLN---RP 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1266953639 103 RSRLGGAKVVWAGDAALLTDAAANALLKTLEEPPENTWFFLACQEPARLLATLRSRC 159
Cdd:PRK05818   83 SVESNGKKIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRC 139
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
 130-158 4.96e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 37.71  E-value: 4.96e-03
                          10        20
                  ....*....|....*....|....*....
gi 1266953639 130 KTLEEPPENTWFFLACQEPARLLATLRSR 158
Cdd:PRK08485   76 KILEEPPKNICFIIVAKSKNLLLPTIRSR 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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