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Conserved domains on  [gi|1039019886|gb|ANM69002|]
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target of AVRB operation1 [Arabidopsis thaliana]

Protein Classification

disease resistance family protein( domain architecture ID 1000118)

disease resistance family protein similar to Nicotiana glutinosa TMV resistance protein N; resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein

Gene Ontology:  GO:0006952

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN03210 super family cl33662
Resistant to P. syringae 6; Provisional
 36-1062 0e+00

Resistant to P. syringae 6; Provisional


The actual alignment was detected with superfamily member PLN03210:

Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 869.96  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   36 QNWLHPVFLSFRGEDVRKGLLSHIQKEFQRNGITPFIDNEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELV 115
Cdd:PLN03210     9 RNWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  116 EIMKCREELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANILGEDSRNWENEADMIIKIS 195
Cdd:PLN03210    89 EIVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  196 KDVSDVLSFTPSKDFDEFVGIEAHTTEITSLLQLDLEEVRMIGIWGPAGIGKTTISRVLYNKLFHQFQLGAIIDNIKVR- 274
Cdd:PLN03210   169 NDVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDRAFISk 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  275 ----YPRPCHDEYSAKLQLQKELLSQMINQKDMVVPHLGVAQERLKDKKVLLVLDDVDGLVQLDAMAKDVQWFGLGSRII 350
Cdd:PLN03210   249 smeiYSSANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSRII 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  351 VVTQDLKLLKAHGIKYIYKVDFPTSDEALEIFCMYAFGEKSPKVGFEQIARTVTTLAGKLPLGLRVMGSYLRRMSKQEWA 430
Cdd:PLN03210   329 VITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKEDWM 408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  431 KSIPRLRTSLDDDIESVLKFSYNSLAEQ-EKDLFLHITCFFRRERIETLEVFLAKKSVDMRQGLQILADKSLLSLNLGNI 509
Cdd:PLN03210   409 DMLPRLRNGLDGKIEKTLRVSYDGLNNKkDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVREDIV 488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  510 EMHNLLVQLGLDIVRKQSiHKPGKRQFLVDTEDICEVLTDDTGTRTLIGIDLELSGVIEgvINISERAFERMCNLQFLRF 589
Cdd:PLN03210   489 EMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDE--LHIHENAFKGMRNLLFLKF 565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  590 HHPYGDRCHDILY-LPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLEKLWDGNEPIRNLKWMDLSFCV 668
Cdd:PLN03210   566 YTKKWDQKKEVRWhLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  669 NLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIgNLTNLKKLFLNRCSSLvklpSSF 748
Cdd:PLN03210   646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI-NLKSLYRLNLSGCSRL----KSF 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  749 GNV-TSLKELNLSGcSSLLEIPSS--IGNIVNLK--KVYADGCSSLVQL--PSSIGNNTNLKELHLLNCSSLMECPSSML 821
Cdd:PLN03210   721 PDIsTNISWLDLDE-TAIEEFPSNlrLENLDELIlcEMKSEKLWERVQPltPLMTMLSPSLTRLFLSDIPSLVELPSSIQ 799

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  822 NLTRLEDLNLSGCLSLVKLPSignVINLQSLYlsdcsslmelpftienatnldTLYLDGCSNLLELPssiwNI-TNLQSL 900
Cdd:PLN03210   800 NLHKLEHLEIENCINLETLPT---GINLESLE---------------------SLDLSGCSRLRTFP----DIsTNISDL 851

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  901 YLNGcSSLKELPSLVENAINLQSLSLMKCSSLVELPSSIWRISNLSYLDVSNCSSLLELNLVShpvVPDSLILDAGDCES 980
Cdd:PLN03210   852 NLSR-TGIEEVPWWIEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDCGALTEASWNG---SPSEVAMATDNIHS 927

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  981 LVQRLDCffqnpkivLNFANCFKLNQEArdLIIQTSACRNAILPGEKVPAYFTYRATGDSLT-VKLNQKYLLQS-LRFKA 1058
Cdd:PLN03210   928 KLPSTVC--------INFINCFNLDQEA--LLQQQSIFKQLILSGEEVPSYFTHRTTGASLTnIPLLHISPCQPfFRFRA 997


                   ....
gi 1039019886 1059 CLLL 1062
Cdd:PLN03210   998 CAVV 1001
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 36-1062 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 869.96  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   36 QNWLHPVFLSFRGEDVRKGLLSHIQKEFQRNGITPFIDNEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELV 115
Cdd:PLN03210     9 RNWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  116 EIMKCREELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANILGEDSRNWENEADMIIKIS 195
Cdd:PLN03210    89 EIVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  196 KDVSDVLSFTPSKDFDEFVGIEAHTTEITSLLQLDLEEVRMIGIWGPAGIGKTTISRVLYNKLFHQFQLGAIIDNIKVR- 274
Cdd:PLN03210   169 NDVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDRAFISk 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  275 ----YPRPCHDEYSAKLQLQKELLSQMINQKDMVVPHLGVAQERLKDKKVLLVLDDVDGLVQLDAMAKDVQWFGLGSRII 350
Cdd:PLN03210   249 smeiYSSANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSRII 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  351 VVTQDLKLLKAHGIKYIYKVDFPTSDEALEIFCMYAFGEKSPKVGFEQIARTVTTLAGKLPLGLRVMGSYLRRMSKQEWA 430
Cdd:PLN03210   329 VITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKEDWM 408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  431 KSIPRLRTSLDDDIESVLKFSYNSLAEQ-EKDLFLHITCFFRRERIETLEVFLAKKSVDMRQGLQILADKSLLSLNLGNI 509
Cdd:PLN03210   409 DMLPRLRNGLDGKIEKTLRVSYDGLNNKkDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVREDIV 488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  510 EMHNLLVQLGLDIVRKQSiHKPGKRQFLVDTEDICEVLTDDTGTRTLIGIDLELSGVIEgvINISERAFERMCNLQFLRF 589
Cdd:PLN03210   489 EMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDE--LHIHENAFKGMRNLLFLKF 565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  590 HHPYGDRCHDILY-LPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLEKLWDGNEPIRNLKWMDLSFCV 668
Cdd:PLN03210   566 YTKKWDQKKEVRWhLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  669 NLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIgNLTNLKKLFLNRCSSLvklpSSF 748
Cdd:PLN03210   646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI-NLKSLYRLNLSGCSRL----KSF 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  749 GNV-TSLKELNLSGcSSLLEIPSS--IGNIVNLK--KVYADGCSSLVQL--PSSIGNNTNLKELHLLNCSSLMECPSSML 821
Cdd:PLN03210   721 PDIsTNISWLDLDE-TAIEEFPSNlrLENLDELIlcEMKSEKLWERVQPltPLMTMLSPSLTRLFLSDIPSLVELPSSIQ 799

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  822 NLTRLEDLNLSGCLSLVKLPSignVINLQSLYlsdcsslmelpftienatnldTLYLDGCSNLLELPssiwNI-TNLQSL 900
Cdd:PLN03210   800 NLHKLEHLEIENCINLETLPT---GINLESLE---------------------SLDLSGCSRLRTFP----DIsTNISDL 851

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  901 YLNGcSSLKELPSLVENAINLQSLSLMKCSSLVELPSSIWRISNLSYLDVSNCSSLLELNLVShpvVPDSLILDAGDCES 980
Cdd:PLN03210   852 NLSR-TGIEEVPWWIEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDCGALTEASWNG---SPSEVAMATDNIHS 927

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  981 LVQRLDCffqnpkivLNFANCFKLNQEArdLIIQTSACRNAILPGEKVPAYFTYRATGDSLT-VKLNQKYLLQS-LRFKA 1058
Cdd:PLN03210   928 KLPSTVC--------INFINCFNLDQEA--LLQQQSIFKQLILSGEEVPSYFTHRTTGASLTnIPLLHISPCQPfFRFRA 997


                   ....
gi 1039019886 1059 CLLL 1062
Cdd:PLN03210   998 CAVV 1001
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 42-199 5.49e-65

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 216.85  E-value: 5.49e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   42 VFLSFRGEDVRKGLLSHIQKEFQRNGITPFID-NEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEIMKC 120
Cdd:pfam01582    3 VFLSFRGSDTREWFVSHLLKELKQKGIKLFIDdRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKILEC 82

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039019886  121 REELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANIlgEDSRNWENEADMIIKISKDVS 199
Cdd:pfam01582   83 ALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDIS 159
TIR smart00255
Toll - interleukin 1 - resistance;
42-176 4.61e-41

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 147.47  E-value: 4.61e-41
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886    42 VFLSFRG-EDVRKGLLSHIQKEFQRNGITPFIDNEMkRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEIMKC 120
Cdd:smart00255    4 VFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFE-PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAALEN 82

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039019886   121 REELGQ-TVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPE-EMVQRWKQALTSAANI 176
Cdd:smart00255   83 ALEEGGlRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEdEKEQFWKKALYAVPSK 140
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
646-926 1.55e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 116.96  E-value: 1.55e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  646 LEKLWDGNEPIRNLKWMDLSFCVNLKELPDFSTATNLQELRLINClslvelpSSIGNATNLLELDLIDCSsLVKLPSSIG 725
Cdd:COG4886     62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQ-LTDLPEELA 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  726 NLTNLKKLFLNRCsSLVKLPSSFGNVTSLKELNLSGCsSLLEIPSSIGNIVNLKKVYADGCsSLVQLPSSIGNNTNLKEL 805
Cdd:COG4886    134 NLTNLKELDLSNN-QLTDLPEPLGNLTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEEL 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  806 HLLNC--SSLmecPSSMLNLTRLEDLNLSGClSLVKLPSIGNVINLQSLYLSDCsSLMELPFtIENATNLDTLYLDGCSN 883
Cdd:COG4886    211 DLSGNqlTDL---PEPLANLTNLETLDLSNN-QLTDLPELGNLTNLEELDLSNN-QLTDLPP-LANLTNLKTLDLSNNQL 284

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1039019886  884 LLELPSSIWNITNLQSLYLNGCSSLKELPSLVENAINLQSLSL 926
Cdd:COG4886    285 TDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLL 327
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 669-807 1.07e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.70  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  669 NLKELPDFSTATNLQELRLI-NCLSLVElpsSIGNATNLLELDLIDcSSLVKLPSsIGNLTNLKKLFLNR---------- 737
Cdd:cd21340     13 NITKIDNLSLCKNLKVLYLYdNKITKIE---NLEFLTNLTHLYLQN-NQIEKIEN-LENLVNLKKLYLGGnrisvvegle 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  738 -CSSL-------VKLP----------SSFGNVTSLKELNLSGCSslLEIPSSIGNIVNLKKVYADGC--SSLVQLPSSIG 797
Cdd:cd21340     88 nLTNLeelhienQRLPpgekltfdprSLAALSNSLRVLNISGNN--IDSLEPLAPLRNLEQLDASNNqiSDLEELLDLLS 165

                          170
                   ....*....|
gi 1039019886  798 NNTNLKELHL 807
Cdd:cd21340    166 SWPSLRELDL 175
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 36-1062 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 869.96  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   36 QNWLHPVFLSFRGEDVRKGLLSHIQKEFQRNGITPFIDNEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELV 115
Cdd:PLN03210     9 RNWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  116 EIMKCREELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANILGEDSRNWENEADMIIKIS 195
Cdd:PLN03210    89 EIVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  196 KDVSDVLSFTPSKDFDEFVGIEAHTTEITSLLQLDLEEVRMIGIWGPAGIGKTTISRVLYNKLFHQFQLGAIIDNIKVR- 274
Cdd:PLN03210   169 NDVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDRAFISk 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  275 ----YPRPCHDEYSAKLQLQKELLSQMINQKDMVVPHLGVAQERLKDKKVLLVLDDVDGLVQLDAMAKDVQWFGLGSRII 350
Cdd:PLN03210   249 smeiYSSANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSRII 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  351 VVTQDLKLLKAHGIKYIYKVDFPTSDEALEIFCMYAFGEKSPKVGFEQIARTVTTLAGKLPLGLRVMGSYLRRMSKQEWA 430
Cdd:PLN03210   329 VITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKEDWM 408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  431 KSIPRLRTSLDDDIESVLKFSYNSLAEQ-EKDLFLHITCFFRRERIETLEVFLAKKSVDMRQGLQILADKSLLSLNLGNI 509
Cdd:PLN03210   409 DMLPRLRNGLDGKIEKTLRVSYDGLNNKkDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVREDIV 488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  510 EMHNLLVQLGLDIVRKQSiHKPGKRQFLVDTEDICEVLTDDTGTRTLIGIDLELSGVIEgvINISERAFERMCNLQFLRF 589
Cdd:PLN03210   489 EMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDE--LHIHENAFKGMRNLLFLKF 565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  590 HHPYGDRCHDILY-LPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLEKLWDGNEPIRNLKWMDLSFCV 668
Cdd:PLN03210   566 YTKKWDQKKEVRWhLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  669 NLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIgNLTNLKKLFLNRCSSLvklpSSF 748
Cdd:PLN03210   646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI-NLKSLYRLNLSGCSRL----KSF 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  749 GNV-TSLKELNLSGcSSLLEIPSS--IGNIVNLK--KVYADGCSSLVQL--PSSIGNNTNLKELHLLNCSSLMECPSSML 821
Cdd:PLN03210   721 PDIsTNISWLDLDE-TAIEEFPSNlrLENLDELIlcEMKSEKLWERVQPltPLMTMLSPSLTRLFLSDIPSLVELPSSIQ 799

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  822 NLTRLEDLNLSGCLSLVKLPSignVINLQSLYlsdcsslmelpftienatnldTLYLDGCSNLLELPssiwNI-TNLQSL 900
Cdd:PLN03210   800 NLHKLEHLEIENCINLETLPT---GINLESLE---------------------SLDLSGCSRLRTFP----DIsTNISDL 851

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  901 YLNGcSSLKELPSLVENAINLQSLSLMKCSSLVELPSSIWRISNLSYLDVSNCSSLLELNLVShpvVPDSLILDAGDCES 980
Cdd:PLN03210   852 NLSR-TGIEEVPWWIEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDCGALTEASWNG---SPSEVAMATDNIHS 927

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  981 LVQRLDCffqnpkivLNFANCFKLNQEArdLIIQTSACRNAILPGEKVPAYFTYRATGDSLT-VKLNQKYLLQS-LRFKA 1058
Cdd:PLN03210   928 KLPSTVC--------INFINCFNLDQEA--LLQQQSIFKQLILSGEEVPSYFTHRTTGASLTnIPLLHISPCQPfFRFRA 997


                   ....
gi 1039019886 1059 CLLL 1062
Cdd:PLN03210   998 CAVV 1001
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 42-199 5.49e-65

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 216.85  E-value: 5.49e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   42 VFLSFRGEDVRKGLLSHIQKEFQRNGITPFID-NEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEIMKC 120
Cdd:pfam01582    3 VFLSFRGSDTREWFVSHLLKELKQKGIKLFIDdRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKILEC 82

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039019886  121 REELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANIlgEDSRNWENEADMIIKISKDVS 199
Cdd:pfam01582   83 ALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDIS 159
TIR smart00255
Toll - interleukin 1 - resistance;
42-176 4.61e-41

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 147.47  E-value: 4.61e-41
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886    42 VFLSFRG-EDVRKGLLSHIQKEFQRNGITPFIDNEMkRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEIMKC 120
Cdd:smart00255    4 VFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFE-PGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAALEN 82

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039019886   121 REELGQ-TVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPE-EMVQRWKQALTSAANI 176
Cdd:smart00255   83 ALEEGGlRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEdEKEQFWKKALYAVPSK 140
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
646-926 1.55e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 116.96  E-value: 1.55e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  646 LEKLWDGNEPIRNLKWMDLSFCVNLKELPDFSTATNLQELRLINClslvelpSSIGNATNLLELDLIDCSsLVKLPSSIG 725
Cdd:COG4886     62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQ-LTDLPEELA 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  726 NLTNLKKLFLNRCsSLVKLPSSFGNVTSLKELNLSGCsSLLEIPSSIGNIVNLKKVYADGCsSLVQLPSSIGNNTNLKEL 805
Cdd:COG4886    134 NLTNLKELDLSNN-QLTDLPEPLGNLTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEEL 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  806 HLLNC--SSLmecPSSMLNLTRLEDLNLSGClSLVKLPSIGNVINLQSLYLSDCsSLMELPFtIENATNLDTLYLDGCSN 883
Cdd:COG4886    211 DLSGNqlTDL---PEPLANLTNLETLDLSNN-QLTDLPELGNLTNLEELDLSNN-QLTDLPP-LANLTNLKTLDLSNNQL 284

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1039019886  884 LLELPSSIWNITNLQSLYLNGCSSLKELPSLVENAINLQSLSL 926
Cdd:COG4886    285 TDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLL 327
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
658-961 2.61e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 104.25  E-value: 2.61e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  658 NLKWMDLSFCVNLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDcsSLVKLPSSIGNLTNLKKLFLNR 737
Cdd:COG4886      4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRD--LLLSSLLLLLSLLLLLLLSLLL 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  738 CSSLVKLPSSFGNVTSLKELNLSGCsslleipSSIGNIVNLKKVYADGCsSLVQLPSSIGNNTNLKELHLLNCsSLMECP 817
Cdd:COG4886     82 LSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSNN-QLTDLP 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  818 SSMLNLTRLEDLNLSGClSLVKLP-SIGNVINLQSLYLSDCsSLMELPFTIENATNLDTLYLDGCsNLLELPSSIWNITN 896
Cdd:COG4886    153 EPLGNLTNLKSLDLSNN-QLTDLPeELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEELDLSGN-QLTDLPEPLANLTN 229

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039019886  897 LQSLYLNGCsSLKELPSLvENAINLQSLSLMKCsSLVELPSSIwRISNLSYLDVSNCsSLLELNL 961
Cdd:COG4886    230 LETLDLSNN-QLTDLPEL-GNLTNLEELDLSNN-QLTDLPPLA-NLTNLKTLDLSNN-QLTDLKL 289
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
600-926 1.07e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.99  E-value: 1.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  600 ILYLPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLEKLWDGNEPIRNLKWMDLSFCvNLKELPD-FST 678
Cdd:COG4886     79 LLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNN-QLTDLPEpLGN 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  679 ATNLQELRLINClSLVELPSSIGNATNLLELDLIDCSsLVKLPSSIGNLTNLKKLFLNRCSsLVKLPSSFGNVTSLKELN 758
Cdd:COG4886    158 LTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNNQ-ITDLPEPLGNLTNLEELDLSGNQ-LTDLPEPLANLTNLETLD 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  759 LSGCSsLLEIPSsIGNIVNLKKVYADGCSsLVQLPSSiGNNTNLKELHLLNcsslmeCPSSMLNLTRLEDLNLSGCLSLV 838
Cdd:COG4886    235 LSNNQ-LTDLPE-LGNLTNLEELDLSNNQ-LTDLPPL-ANLTNLKTLDLSN------NQLTDLKLKELELLLGLNSLLLL 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  839 KLPSIGNVINLQSLYLSDCSSLMELPFTIENATNLDTLYLDGCSNLLELPSSIWNITNLQSLYLNGCSSLKELPSLVENA 918
Cdd:COG4886    305 LLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLAL 384


                   ....*...
gi 1039019886  919 INLQSLSL 926
Cdd:COG4886    385 LLLTLLLL 392
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
705-953 2.01e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.22  E-value: 2.01e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  705 NLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRCSSLVKLPSSFGNVTSLKELNLSGCSSLLEIPSSIGNIVNLKKVYAD 784
Cdd:COG4886      1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  785 GCSSLVQLPSSIGNNTNLKELHLLNCSSLmecpssmLNLTRLEDLNLSGClSLVKLP-SIGNVINLQSLYLSDCsSLMEL 863
Cdd:COG4886     81 LLSLLLLGLTDLGDLTNLTELDLSGNEEL-------SNLTNLESLDLSGN-QLTDLPeELANLTNLKELDLSNN-QLTDL 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  864 PFTIENATNLDTLYLDGCsNLLELPSSIWNITNLQSLYLNGCsSLKELPSLVENAINLQSLSLMKCsSLVELPSSIWRIS 943
Cdd:COG4886    152 PEPLGNLTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNN-QITDLPEPLGNLTNLEELDLSGN-QLTDLPEPLANLT 228

                          250
                   ....*....|
gi 1039019886  944 NLSYLDVSNC 953
Cdd:COG4886    229 NLETLDLSNN 238
NB-ARC pfam00931
NB-ARC domain;
232-454 4.42e-15

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 76.26  E-value: 4.42e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  232 EEVRMIGIWGPAGIGKTTISRVLYNK---LFHQFQlgaIIDNIKVRyprpchDEYSAKLQLQKELLSQMINQKDMVVPHL 308
Cdd:pfam00931   16 DEPGIVGIHGMGGVGKTTLAAQIFNDfdeVEGHFD---SVAWVVVS------KTFTISTLQQTILQNLGLSEDDWDNKEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  309 GVAQER----LKDKKVLLVLDDVDGLVQLDAMAKDVQWFGLGSRIIVVTQDLKLLKAHG-IKYIYKVDFPTSDEALEIFC 383
Cdd:pfam00931   87 GELARKirraLLTKRFLLVLDDVWDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAGRVGgPSDPHEVELLEPDEAWELFE 166

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039019886  384 MYAF-GEKSPKVGFEQIARTVTTLAGKLPLGLRVMGSYLR-RMSKQEWAKSIPRL---RTSLDDDIESV---LKFSYNS 454
Cdd:pfam00931  167 NKVFpKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLScKKTVEEWKHVYDVLqseLKSNSYSLNSVrsiLQLSYEN 245
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
 42-139 3.54e-14

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 70.04  E-value: 3.54e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   42 VFLSFRGEDvrKGLLSHIQKEFQRNGITPFID-NEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELvEIMKC 120
Cdd:pfam13676    1 VFISYAGED--RAWAEWLADALEAAGYRVWLDrWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEW-EAALA 77

                           90
                   ....*....|....*....
gi 1039019886  121 REELGQTVMTVFYDVDPSD 139
Cdd:pfam13676   78 DPEGRKRLIPVRLECDLEL 96
PLN03194 PLN03194
putative disease resistance protein; Provisional
 39-193 6.33e-14

putative disease resistance protein; Provisional


Pssm-ID: 215626 [Multi-domain]  Cd Length: 187  Bit Score: 71.39  E-value: 6.33e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   39 LHPVFLSFRGEDVRKGLLSHIQKEFQRNGITPFIDNE-MKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEI 117
Cdd:PLN03194    26 PCDVFINHRGIDTKRTIATLLYDHLSRLNLRPFLDNKnMKPGDKLFDKINSAIRNCKVGVAVFSPRYCESYFCLHELALI 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  118 MKCREElgqtVMTVFYDVDPSDVRkqkgdfgKVFKKTCvgrPEEMVQRWKQALTSAANILG--EDS--RNWE----NEAD 189
Cdd:PLN03194   106 MESKKR----VIPIFCDVKPSQLR-------VVDNGTC---PDEEIRRFNWALEEAKYTVGltFDSlkGNWSevvtMASD 171


                   ....
gi 1039019886  190 MIIK 193
Cdd:PLN03194   172 AVIK 175
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 603-964 4.68e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 67.18  E-value: 4.68e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  603 LPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLE-KLWDGNEPIRNLKWMDLSFCV----------NLK 671
Cdd:PLN00113   109 IPDDIFTTSSSLRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVlvgkipnsltNLT 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  672 ELPDFSTATN------------LQELRLI----NCLSlVELPSSIGNATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFL 735
Cdd:PLN00113   189 SLEFLTLASNqlvgqiprelgqMKSLKWIylgyNNLS-GEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFL 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  736 NRCSSLVKLPSSFGNVTSLKELNLSGCSSLLEIPSSIGNIVNLKKVY----------ADGCSSLVQL------------- 792
Cdd:PLN00113   268 YQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHlfsnnftgkiPVALTSLPRLqvlqlwsnkfsge 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  793 -PSSIGNNTNLKELHLLNCSSLMECPSSMLNLTRLEDLNL-SGCLSLVKLPSIGNVINLQSLYLSDCSSLMELPftiENA 870
Cdd:PLN00113   348 iPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILfSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELP---SEF 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  871 TNLDTLY-LDGCSNLLE--LPSSIWNITNLQSLYLNGCSSLKELPSLVeNAINLQSL-------------SLMKCSSLVE 934
Cdd:PLN00113   425 TKLPLVYfLDISNNNLQgrINSRKWDMPSLQMLSLARNKFFGGLPDSF-GSKRLENLdlsrnqfsgavprKLGSLSELMQ 503

                          410       420       430
                   ....*....|....*....|....*....|
gi 1039019886  935 LPSSIWRISNLSYLDVSNCSSLLELNLvSH 964
Cdd:PLN00113   504 LKLSENKLSGEIPDELSSCKKLVSLDL-SH 532
C-JID pfam20160
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ...
 1023-1059 3.51e-06

C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions.


Pssm-ID: 466313  Cd Length: 108  Bit Score: 47.06  E-value: 3.51e-06
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1039019886 1023 LPGEKVPAYFTYRATGDSLTVKLNQKYLL-QSLRFKAC 1059
Cdd:pfam20160    1 LPGSQIPEWFNHQSTGSSISIKLPENWYNdNFLGFAVC 38
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 702-954 1.38e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.46  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  702 NATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRCSSLVKLPSS-FGNVTSLKELNLSGCSSLLEIPSsiGNIVNLKK 780
Cdd:PLN00113    67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLET 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  781 VYADGCSSLVQLPSSIGNNTNLKELHLLNCSSLMECPSSMLNLTRLEDLNLSGCLSLVKLPS-IGNVINLQSLYLSDCSS 859
Cdd:PLN00113   145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPReLGQMKSLKWIYLGYNNL 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  860 LMELPFTIENATNLDtlYLDGCSNLL--ELPSSIWNITNLQSLYLngcsslkelpslVENAINLQslslmkcsslveLPS 937
Cdd:PLN00113   225 SGEIPYEIGGLTSLN--HLDLVYNNLtgPIPSSLGNLKNLQYLFL------------YQNKLSGP------------IPP 278

                          250
                   ....*....|....*..
gi 1039019886  938 SIWRISNLSYLDVSNCS 954
Cdd:PLN00113   279 SIFSLQKLISLDLSDNS 295
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
200-331 2.58e-05

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 47.92  E-value: 2.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  200 DVLS--FTPskdfDEFVGIEAHTTEITSLLQ--LDLEEVRMIGIWGPAGIGKTTISRvlynKLFHQFQLGAIIDNIKVRY 275
Cdd:COG1474     17 EVLSpdYVP----DRLPHREEEIEELASALRpaLRGERPSNVLIYGPTGTGKTAVAK----YVLEELEEEAEERGVDVRV 88

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039019886  276 PR-PCHDEYSaklqlQKELLSQMINQ--KDMVVPHLGVAQERL----------KDKKVLLVLDDVDGLV 331
Cdd:COG1474     89 VYvNCRQAST-----RYRVLSRILEElgSGEDIPSTGLSTDELfdrlyealdeRDGVLVVVLDEIDYLV 152
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 659-781 2.02e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.61  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  659 LKWMDLSFCVNLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRC 738
Cdd:PLN00113   454 LQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHN 533

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1039019886  739 SSLVKLPSSFGNVTSLKELNLSgCSSLL-EIPSSIGNIVNLKKV 781
Cdd:PLN00113   534 QLSGQIPASFSEMPVLSQLDLS-QNQLSgEIPKNLGNVESLVQV 576
PLN03150 PLN03150
hypothetical protein; Provisional
 696-773 3.08e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.81  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  696 LPSSIGNATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFL--NRCSSLVklPSSFGNVTSLKELNLSGCSSLLEIPSSIG 773
Cdd:PLN03150   434 IPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLsyNSFNGSI--PESLGQLTSLRILNLNGNSLSGRVPAALG 511
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 208-272 4.48e-04

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 43.92  E-value: 4.48e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039019886  208 KDFDEFVGIEaHTTEITSLLQLDLEEVR---MIgIWGPAGIGKTTISRVLYNKL-FHQFQLGAIIDNIK 272
Cdd:PRK13342     9 KTLDEVVGQE-HLLGPGKPLRRMIEAGRlssMI-LWGPPGTGKTTLARIIAGATdAPFEALSAVTSGVK 75
PLN03150 PLN03150
hypothetical protein; Provisional
 720-797 6.30e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.04  E-value: 6.30e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039019886  720 LPSSIGNLTNLKKLFLNRCSSLVKLPSSFGNVTSLKELNLSGCSSLLEIPSSIGNIVNLKKVYADGCSSLVQLPSSIG 797
Cdd:PLN03150   434 IPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
PLN03150 PLN03150
hypothetical protein; Provisional
 675-749 9.65e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.27  E-value: 9.65e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039019886  675 DFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRCSSLVKLPSSFG 749
Cdd:PLN03150   437 DISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 669-807 1.07e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.70  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  669 NLKELPDFSTATNLQELRLI-NCLSLVElpsSIGNATNLLELDLIDcSSLVKLPSsIGNLTNLKKLFLNR---------- 737
Cdd:cd21340     13 NITKIDNLSLCKNLKVLYLYdNKITKIE---NLEFLTNLTHLYLQN-NQIEKIEN-LENLVNLKKLYLGGnrisvvegle 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  738 -CSSL-------VKLP----------SSFGNVTSLKELNLSGCSslLEIPSSIGNIVNLKKVYADGC--SSLVQLPSSIG 797
Cdd:cd21340     88 nLTNLeelhienQRLPpgekltfdprSLAALSNSLRVLNISGNN--IDSLEPLAPLRNLEQLDASNNqiSDLEELLDLLS 165

                          170
                   ....*....|
gi 1039019886  798 NNTNLKELHL 807
Cdd:cd21340    166 SWPSLRELDL 175
LRR_3 pfam07725
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ...
 635-653 2.05e-03

Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.


Pssm-ID: 429621 [Multi-domain]  Cd Length: 20  Bit Score: 36.55  E-value: 2.05e-03
                           10
                   ....*....|....*....
gi 1039019886  635 FLVKINMRDSMLEKLWDGN 653
Cdd:pfam07725    1 NLVELNMPYSKLEKLWEGV 19
COG4916 COG4916
Uncharacterized conserved protein [Function unknown];
42-145 3.62e-03

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443944 [Multi-domain]  Cd Length: 236  Bit Score: 40.48  E-value: 3.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886   42 VFLSFRGEDvrKGLLSHIQKEFQRNGITPFIDNEMKR---GGSIgPELLQAI--RGSKIAIILLSRNYGSSKWCLDELvE 116
Cdd:COG4916      3 VALSFAGED--REFVERVAEALKARGIKVFYDENEEAelwGKDL-DEYLQDIyrSESRFVVVFLSKDYVEKKWTGLER-R 78

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1039019886  117 IMKCREELGQT--VMTVFYD-VDPSDVRKQKG 145
Cdd:COG4916     79 AALARAMQRKKeyILPIRLDdTEIPGILATIG 110
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
 208-272 5.83e-03

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 40.42  E-value: 5.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  208 KDFDEFVG--------------IEAHTteITSllqldleevrMIgIWGPAGIGKTTISRVLYNKLFHQF-QLGAIIDNIK 272
Cdd:COG2256     22 RTLDEVVGqehllgpgkplrraIEAGR--LSS----------MI-LWGPPGTGKTTLARLIANATDAEFvALSAVTSGVK 88
AMN1 cd09293
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ...
 704-911 9.57e-03

Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.


Pssm-ID: 187754 [Multi-domain]  Cd Length: 226  Bit Score: 38.85  E-value: 9.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  704 TNLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRCSS-----LVKLPSSFGNvtsLKELNLSGCSslleipssigNIVNl 778
Cdd:cd09293     28 SGLEWLELYMCPISDPPLDQLSNCNKLKKLILPGSKLiddegLIALAQSCPN---LQVLDLRACE----------NITD- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  779 kkvyadgcSSLVQLPssignnTNLKELHLLNCSSLMECpssmlnltrledlNLSGCLSLVKLpsIGNVINLQSLYLSDC- 857
Cdd:cd09293     94 --------SGIVALA------TNCPKLQTINLGRHRNG-------------HLITDVSLSAL--GKNCTFLQTVGFAGCd 144

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  858 ---SSLMELpfTIENATNLDTLYLDGCsnllelpssiWNITNL---QSLYLNGCSSLKEL 911
Cdd:cd09293    145 vtdKGVWEL--ASGCSKSLERLSLNNC----------RNLTDQsipAILASNYFPNLSVL 192
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 823-959 9.85e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.00  E-value: 9.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039019886  823 LTRLEDLNLSGClSLVKLPSIGNVINLQSLYLSD-CSSLMElpfTIENATNLDTLYLDGcsNLLELPSSIWNITNLQSLY 901
Cdd:cd21340      1 LKRITHLYLNDK-NITKIDNLSLCKNLKVLYLYDnKITKIE---NLEFLTNLTHLYLQN--NQIEKIENLENLVNLKKLY 74

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039019886  902 LNG-----------CSSLKELpsLVENainlQSLSlmKCSSLVELPSSIWRISN-LSYLDVSNC--SSLLEL 959
Cdd:cd21340     75 LGGnrisvveglenLTNLEEL--HIEN----QRLP--PGEKLTFDPRSLAALSNsLRVLNISGNniDSLEPL 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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