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Conserved domains on  [gi|1005660431|gb|AMQ20650|]
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cytosolic protein [Geobacillus sp. JS12]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
dnaA super family cl42516
chromosomal replication initiator protein DnaA;
7-86 9.07e-14

chromosomal replication initiator protein DnaA;


The actual alignment was detected with superfamily member TIGR00362:

Pssm-ID: 455861 [Multi-domain]  Cd Length: 437  Bit Score: 66.40  E-value: 9.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005660431   7 WEQVKTKLAQKLSGPSFDTWFASTSA-TVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGREMRIFVSVHGERQKI 85
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80


                  .
gi 1005660431  86 E 86
Cdd:TIGR00362  81 E 81
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 7-86 9.07e-14

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 66.40  E-value: 9.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005660431   7 WEQVKTKLAQKLSGPSFDTWFASTSA-TVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGREMRIFVSVHGERQKI 85
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80


                  .
gi 1005660431  86 E 86
Cdd:TIGR00362  81 E 81
PRK06672 PRK06672
hypothetical protein; Validated
 7-92 2.51e-12

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 62.47  E-value: 2.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005660431   7 WEQVKTKLAQKLSGPSFDTWFASTSATVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGREMRI-FVSVHGERQKI 85
Cdd:PRK06672    5 WTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIqFDLCNGEPSNL 84


                  ....*..
gi 1005660431  86 EERLEQR 92
Cdd:PRK06672   85 KDVQKEK 91
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 4-66 1.94e-08

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 47.66  E-value: 1.94e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1005660431   4 HHLWEQVKTKLAQKLSGPSFDTWFASTSAT--VDDDWLIIECLNDIQCEWLQTRYGELISETVRE 66
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVdlDDGGSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 7-86 9.07e-14

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 66.40  E-value: 9.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005660431   7 WEQVKTKLAQKLSGPSFDTWFASTSA-TVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGREMRIFVSVHGERQKI 85
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80


                  .
gi 1005660431  86 E 86
Cdd:TIGR00362  81 E 81
PRK06672 PRK06672
hypothetical protein; Validated
 7-92 2.51e-12

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 62.47  E-value: 2.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005660431   7 WEQVKTKLAQKLSGPSFDTWFASTSATVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGREMRI-FVSVHGERQKI 85
Cdd:PRK06672    5 WTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIqFDLCNGEPSNL 84


                  ....*..
gi 1005660431  86 EERLEQR 92
Cdd:PRK06672   85 KDVQKEK 91
dnaA PRK00149
chromosomal replication initiator protein DnaA;
3-65 1.19e-09

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 54.76  E-value: 1.19e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1005660431   3 EHHLWEQVKTKLAQKLSGPSFDTWFASTS-ATVDDDWLIIECLNDIQCEWLQTRYGELISETVR 65
Cdd:PRK00149    2 LQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ 65
PRK06672 PRK06672
hypothetical protein; Validated
 6-129 2.23e-09

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 54.00  E-value: 2.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005660431   6 LWEQVKTKLAQKLSGPSFDTWFASTSATVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGR------EMRIFVSVH 79
Cdd:PRK06672  194 IWNKIKDKMQLKISRPSYETWVKETTARINEDSLIIYFENEFQQEWVKKSYKDLISQIAKELTGNtyeiqfELKSNTTSN 273

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1005660431  80 GERQKIEE---RLEQRYGAPMTFRQY--ITRLERQMEELERRIDHYARIIDELLE 129
Cdd:PRK06672  274 NEKSTIKDitsELGEQFKVSNNSLKYndVDESNKRIRALEEKIMNLEKVIGTLVE 328
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 4-66 1.94e-08

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 47.66  E-value: 1.94e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1005660431   4 HHLWEQVKTKLAQKLSGPSFDTWFASTSAT--VDDDWLIIECLNDIQCEWLQTRYGELISETVRE 66
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVdlDDGGSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
PRK06672 PRK06672
hypothetical protein; Validated
 7-78 6.03e-07

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 47.06  E-value: 6.03e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1005660431   7 WEQVKTKLAQKLSGPSFDTWFASTSATVDDDWLIIECLNDIQCEWLQTRYGELISETVREVFGREMRIFVSV 78
Cdd:PRK06672   95 WDEVKKALRPKIAEKTFMTWIRNTNATIKDNKVIIFCEDAFHRDLLEGEYKNIISSTVQKITDEEYQIWFEI 166
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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