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Conserved domains on  [gi|954626996|gb|ALP52080|]
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hypothetical protein Tel_02390 [Candidatus Tenderia electrophaga]

Protein Classification

class I adenylate cyclase( domain architecture ID 11459653)

class I adenylate cyclase catalyzes the conversion of ATP to cyclic AMP and pyrophosphate

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
CyaA COG3072
Adenylate cyclase, class I [Signal transduction mechanisms];
14-941 0e+00

Adenylate cyclase, class I [Signal transduction mechanisms];


:

Pssm-ID: 442306  Cd Length: 930  Bit Score: 1247.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  14 DVDAVRKRFITLNRQRLQRGEECMRSNQRDFLDFLPLLFHINHPSLPGYVSKLTPSGICDYTPTQRALDAAKKYIHRFDY 93
Cdd:COG3072   10 DLKTLRQRFLALNQLRLERALSAMSSRQQQVLDLLPLLFHYNHPLLPGYVSGDVPAGIANFTPDKRQLQALQRLARSFDY 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  94 RNRALPRYDILSMFLMGSSGTIAYSRKSDFDIWLCHQHDIPADRLAELQQKASLIEQWADEQGLEVHFFLMDAEDFRQGK 173
Cdd:COG3072   90 KQRAQHEPPILGLYLMGSTGSIAQSESSDLDIWVCHDPDLDAEARALLQQKCELIEQWAASLGVEVHFFLMDENRFRHGE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 174 IVDLSSESSGTAQYYLLLEEFYRTSLLLAGRFPVWWLVPVEEEENYAAYVDNLYQSRLVNESEVIDFGGIPTLPAEEFFG 253
Cdd:COG3072  170 RESLSGENCGSAQHLLLLDEFYRTAILLAGKRPLWWLVPPEEEHNYDEYVQTLLAKGFINPDEWLDFGGLGTIPAEEYFG 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 254 AAVWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYKKLEEYLLSRDEEDRLELV 333
Cdd:COG3072  250 AGLWQLYKGIDSPYKSVLKLLLLEAYSSEYPNTQLLSLEFKQAVYAGELDLDELDPYVMMLRRVTRYLLERNDLKRLELV 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 334 RRCFYFKVNQKLSRKD-NVPYDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAVLVKELTYTYQFLSSFARQ 412
Cdd:COG3072  330 RRCFYLKVNEKLSRPPrERSKSWRRELLERLVREWGWSEERLALLDNRAQWKIEQVREERNELVDELMQSYRNLIQFARR 409
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 413 HAQLAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQRGREG-GWALLSsgGDSDSRDPSSMVA 491
Cdd:COG3072  410 NNISSSISPQDIGILGRKLYAAFERLPGKVTLINPGISPDLSEENLTFIQVPEGRANRaGWYLYN--QSLTPADIIGRQP 487
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 492 LKRSRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALPASkILETDIEELGRAVKVLESVLVVNLG 571
Cdd:COG3072  488 LKYSRSLVELVAWCYFNGLLTASTRLHLHPGGSDLDEYELQQLVADLRQHFPVP-LPAPSNEALSRPCEIRHLALFINLG 566
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 572 HDPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCLSNYFRMMPPSKgAAPPTPT 651
Cdd:COG3072  567 VDPTAHLSRRGIHFDSSRSDALSFGGARENLVGSIDLVYRNSWNEVRTLHFEGDDALLDALKTLLGKMHQDA-APPPSID 645
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 652 VLCYTQNHAITIRQRVERLFDDLVECFYGAREKQNNRFIFCVQRDYYVLYFEDDVMRYQRISDYGELLRYLSKGRQSFGQ 731
Cdd:COG3072  646 VFCYSQTRRGAIANRVEQLFNECISLRLGGTRQPNRRYLLRVAGQYYGLFFERRGVSVQKLENAVDLYRALSENKLSYSP 725
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 732 VTMDPNVISDK-LLALVFKFNKPGMVQFFYKRESGGnAEVYVVDENGSLFCQKHEAADEACLLGHYSRFFDTVLQRQLFQ 810
Cdd:COG3072  726 LVLDRHALEDHpLPPVIDSFASEGLIQFFFEDNGDG-FNIYILDENNSLEIYRQCEGDKEELLRPLNRFYRSSQDRRTYG 804
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 811 IIGQGeegkeAIEVEYYSVGRDRQGQYQVSRRAPHDSGKRG-YTSIQVIASREDasGSAFTIYCDEKEFSSLEYGSNLFT 889
Cdd:COG3072  805 SSFIN-----FNLPQFYQIVRNDGGELQVEPFRSPLAASDAnYYEVQAIGDEGD--DSLFEFYCDCQEFESLELEGDLLL 877
                        890       900       910       920       930
                 ....*....|....*....|....*....|....*....|....*....|..
gi 954626996 890 EIAVNILAKRKSRRTYPVYITDIDLTPDMFADYPAGHVPVVEFLNYKKNIEA 941
Cdd:COG3072  878 VAAVAILLRRRRRRPYPYYITDDDLLSALELDEQLEQQTVQTLQYLKYLEAL 929
 
Name Accession Description Interval E-value
CyaA COG3072
Adenylate cyclase, class I [Signal transduction mechanisms];
14-941 0e+00

Adenylate cyclase, class I [Signal transduction mechanisms];


Pssm-ID: 442306  Cd Length: 930  Bit Score: 1247.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  14 DVDAVRKRFITLNRQRLQRGEECMRSNQRDFLDFLPLLFHINHPSLPGYVSKLTPSGICDYTPTQRALDAAKKYIHRFDY 93
Cdd:COG3072   10 DLKTLRQRFLALNQLRLERALSAMSSRQQQVLDLLPLLFHYNHPLLPGYVSGDVPAGIANFTPDKRQLQALQRLARSFDY 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  94 RNRALPRYDILSMFLMGSSGTIAYSRKSDFDIWLCHQHDIPADRLAELQQKASLIEQWADEQGLEVHFFLMDAEDFRQGK 173
Cdd:COG3072   90 KQRAQHEPPILGLYLMGSTGSIAQSESSDLDIWVCHDPDLDAEARALLQQKCELIEQWAASLGVEVHFFLMDENRFRHGE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 174 IVDLSSESSGTAQYYLLLEEFYRTSLLLAGRFPVWWLVPVEEEENYAAYVDNLYQSRLVNESEVIDFGGIPTLPAEEFFG 253
Cdd:COG3072  170 RESLSGENCGSAQHLLLLDEFYRTAILLAGKRPLWWLVPPEEEHNYDEYVQTLLAKGFINPDEWLDFGGLGTIPAEEYFG 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 254 AAVWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYKKLEEYLLSRDEEDRLELV 333
Cdd:COG3072  250 AGLWQLYKGIDSPYKSVLKLLLLEAYSSEYPNTQLLSLEFKQAVYAGELDLDELDPYVMMLRRVTRYLLERNDLKRLELV 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 334 RRCFYFKVNQKLSRKD-NVPYDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAVLVKELTYTYQFLSSFARQ 412
Cdd:COG3072  330 RRCFYLKVNEKLSRPPrERSKSWRRELLERLVREWGWSEERLALLDNRAQWKIEQVREERNELVDELMQSYRNLIQFARR 409
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 413 HAQLAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQRGREG-GWALLSsgGDSDSRDPSSMVA 491
Cdd:COG3072  410 NNISSSISPQDIGILGRKLYAAFERLPGKVTLINPGISPDLSEENLTFIQVPEGRANRaGWYLYN--QSLTPADIIGRQP 487
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 492 LKRSRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALPASkILETDIEELGRAVKVLESVLVVNLG 571
Cdd:COG3072  488 LKYSRSLVELVAWCYFNGLLTASTRLHLHPGGSDLDEYELQQLVADLRQHFPVP-LPAPSNEALSRPCEIRHLALFINLG 566
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 572 HDPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCLSNYFRMMPPSKgAAPPTPT 651
Cdd:COG3072  567 VDPTAHLSRRGIHFDSSRSDALSFGGARENLVGSIDLVYRNSWNEVRTLHFEGDDALLDALKTLLGKMHQDA-APPPSID 645
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 652 VLCYTQNHAITIRQRVERLFDDLVECFYGAREKQNNRFIFCVQRDYYVLYFEDDVMRYQRISDYGELLRYLSKGRQSFGQ 731
Cdd:COG3072  646 VFCYSQTRRGAIANRVEQLFNECISLRLGGTRQPNRRYLLRVAGQYYGLFFERRGVSVQKLENAVDLYRALSENKLSYSP 725
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 732 VTMDPNVISDK-LLALVFKFNKPGMVQFFYKRESGGnAEVYVVDENGSLFCQKHEAADEACLLGHYSRFFDTVLQRQLFQ 810
Cdd:COG3072  726 LVLDRHALEDHpLPPVIDSFASEGLIQFFFEDNGDG-FNIYILDENNSLEIYRQCEGDKEELLRPLNRFYRSSQDRRTYG 804
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 811 IIGQGeegkeAIEVEYYSVGRDRQGQYQVSRRAPHDSGKRG-YTSIQVIASREDasGSAFTIYCDEKEFSSLEYGSNLFT 889
Cdd:COG3072  805 SSFIN-----FNLPQFYQIVRNDGGELQVEPFRSPLAASDAnYYEVQAIGDEGD--DSLFEFYCDCQEFESLELEGDLLL 877
                        890       900       910       920       930
                 ....*....|....*....|....*....|....*....|....*....|..
gi 954626996 890 EIAVNILAKRKSRRTYPVYITDIDLTPDMFADYPAGHVPVVEFLNYKKNIEA 941
Cdd:COG3072  878 VAAVAILLRRRRRRPYPYYITDDDLLSALELDEQLEQQTVQTLQYLKYLEAL 929
cyaA PRK09450
class I adenylate cyclase;
19-811 0e+00

class I adenylate cyclase;


Pssm-ID: 236522 [Multi-domain]  Cd Length: 830  Bit Score: 870.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  19 RKRFITLNRQRLQRGEECMRSNQRDFLDFLPLLFHINHPSLPGYVSKLTPSGICDYTPTQRALDAAKKYIHRFDYRNRAL 98
Cdd:PRK09450   9 KQRLDALNQLRLARALAALSPAFQQVLSLLPLLLHVNHPLLPGYVSGNTPAGICNFTPDETQLAYLQRLELSFGYSVQDP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  99 PRYD--ILSMFLMGSSGTIAYSRKSDFDIWLCHQHDIPADRLAELQQKASLIEQWADEQGLEVHFFLMDAEDFRQGKI-V 175
Cdd:PRK09450  89 PKGElpITGLYTMGSTGSIGQSESSDLDIWVCHRPWLDAEERQLLQRKCSLLEQWAASLGVEVNFFLMDEERFRHNESgS 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 176 DLSSESSGTAQYYLLLEEFYRTSLLLAGRFPVWWLVPVEEEENYAAYVDNLYQSRLVNESEVIDFGGIPTLPAEEFFGAA 255
Cdd:PRK09450 169 ALGGEDCGSTQHILLLDEFYRTAIRLAGKRPLWWLVPVEEEEHYDDYVMTLYSKGFLNPNEWLDLGGLSSLPAEEYFGAS 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 256 VWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYKKLEEYLLSRDEEDRLELVRR 335
Cdd:PRK09450 249 LWQLYKGIDSPYKSVLKLLLLEAYSSEYPNTQLLSLDFKQRLLAGEIDSDGLDPYCLMLERVTRYLTAINDPTRLELVRR 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 336 CFYFKVNQKLSRKDNVPyDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAVLVKELTYTYQFLSSFARQHAQ 415
Cdd:PRK09450 329 CFYLKVGEKLSRERACV-GWRRELLSQLVSEWGWDEERLALLDNRANWKIGQVREFHNELVDALMQSYRNLIRFARRNNL 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 416 LAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQ-RGREGGWALLSsgGDSDSRDPSSMVALKR 494
Cdd:PRK09450 408 SSSISPQDIGILTRKLYAAFERLPGKVTLLNPQISPDLSEPDLTFIEVPPgRANRSGWYLYN--QAPDPDSIIGHQPLEY 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 495 SRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALP--ASKIletDIEELGRAVKVLESVLVVNLGH 572
Cdd:PRK09450 486 NRYLNKLVAWAYFNGLLTSSTRLHLKGNGSDLDLAKLQELVADLRQHFPlrLPAP---TPQALLQPCEIRHLLIIVNLEV 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 573 DPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCLSNYFRMMPPSkGAAPPTPTV 652
Cdd:PRK09450 563 DPTAHLRGQVVHFDFRNLDVFSFGGEQENLVGSVDLIYRNSWNEVRTLHFEGEQALLDALKTILGKMHQD-AAPPPSVEV 641
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 653 LCYTQNHAITIRQRVERLFDDLVECFYGAREKQnNRFIFCVQRDYYVLYFEDDVMRYQRISDYGELLRYLSKGRQSFGQV 732
Cdd:PRK09450 642 FCYSQHLRGLIRTRVQQLVSECIELRLGSTRQE-PGKALRVAGQTWGLFFERLGVSVQKLENAVEFYGALSENKLHGLPV 720
                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 954626996 733 TMDPNviSDKLLALVFKFNKPGMVQFFYkRESGGNAEVYVVDENGSLFCQKHEAADEACLLGHYSRFFDTVLQRQLFQI 811
Cdd:PRK09450 721 QLDTN--FLKLPAVVDGFASEGIIQFFF-EDNEDGFNVYILDESNRLEHYHHCEGSKEELVRDVSRFYSSSHDRFTYGS 796
Adenylate_cycl pfam01295
Adenylate cyclase, class-I;
236-817 3.74e-137

Adenylate cyclase, class-I;


Pssm-ID: 426186  Cd Length: 601  Bit Score: 423.59  E-value: 3.74e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  236 EVIDFGGIPTLPAEEFFGAAVWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYK 315
Cdd:pfam01295   1 DWLDLGGLSALPAEEYFGASLWQLYKGIDSPYKAVLKILLLEAYSSEYPNTELLSSQFKRRLLAGDFTSYHLDPYLLMLE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  316 KLEEYLLSRDEEDRLELVRRCFYFKVNQKLSRKD-NVPYDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAV 394
Cdd:pfam01295  81 RVTDYLTKINDFKRLDLVRRCFYLKAGEGLSRLQpNGAKDWRRDKLQELVQQWHWSDELIQTLDNRRHWKVGQVKWANNQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  395 LVKELTYTYQFLSSFARQHAQLAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQ-RGREGGWA 473
Cdd:pfam01295 161 LLELLMLSYRNLIQFARKHNISESISPEDIGILTRKLYTAFEELPGKVTLLNPLISPDLSEPDLTFIEVPEgRSNKAGWY 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  474 LLSSGgdSDSRDPSSMVALKRSRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALPaSKILETDIE 553
Cdd:pfam01295 241 LYNQP--PDPADLIGRRPLEYAKYLSKLVAWAYFNGLLTESTRLHLVSQGVDLTSDKLSQFVTDLRLSFP-VRAPKPTNQ 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  554 ELGRAVKVLESVLVVNLGHDPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCL- 632
Cdd:pfam01295 318 DLSHPCEIRHLVIFINLEQDPTTHWSGQEVMVDIQNADLFSFGRSQENLVGSVDLIYRNSWNEIRTLHFEGENALLKALk 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  633 --SNYFRmmppsKGAAPP-TPTVLCYTQNHAITIRQRVERLFDDLVECFYGAREKQNNRFIFCVQRDYYVLYFEDDVMRY 709
Cdd:pfam01295 398 tiLNKIH-----RDAAPPeSIDVFCYSRRLRSQLRNAVKQLLNRCIELRLGTIQSRTQVKPLRIGGKNYGLFFERRGVSV 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  710 QRISDYGELLRYLSKGRQSFGQVTMDPNVISDKLLALVFKFNKPGMVQFFYkRESGGNAEVYVVDENGSLFCQKHEAADE 789
Cdd:pfam01295 473 QDLENAVDFYGQISRNKLVELPRPELGDDPFLHIPAIIDAFASEGLIQFFF-EDNEDGFNVYILDEKNELEIYHQCDGSK 551
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 954626996  790 ACLLGHYSRFFDTVLQR-------------QLFQIIGQGEE 817
Cdd:pfam01295 552 DELVNEVNRFYASSESRkntnpafinfnlpQFYQLVRVNGE 592
 
Name Accession Description Interval E-value
CyaA COG3072
Adenylate cyclase, class I [Signal transduction mechanisms];
14-941 0e+00

Adenylate cyclase, class I [Signal transduction mechanisms];


Pssm-ID: 442306  Cd Length: 930  Bit Score: 1247.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  14 DVDAVRKRFITLNRQRLQRGEECMRSNQRDFLDFLPLLFHINHPSLPGYVSKLTPSGICDYTPTQRALDAAKKYIHRFDY 93
Cdd:COG3072   10 DLKTLRQRFLALNQLRLERALSAMSSRQQQVLDLLPLLFHYNHPLLPGYVSGDVPAGIANFTPDKRQLQALQRLARSFDY 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  94 RNRALPRYDILSMFLMGSSGTIAYSRKSDFDIWLCHQHDIPADRLAELQQKASLIEQWADEQGLEVHFFLMDAEDFRQGK 173
Cdd:COG3072   90 KQRAQHEPPILGLYLMGSTGSIAQSESSDLDIWVCHDPDLDAEARALLQQKCELIEQWAASLGVEVHFFLMDENRFRHGE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 174 IVDLSSESSGTAQYYLLLEEFYRTSLLLAGRFPVWWLVPVEEEENYAAYVDNLYQSRLVNESEVIDFGGIPTLPAEEFFG 253
Cdd:COG3072  170 RESLSGENCGSAQHLLLLDEFYRTAILLAGKRPLWWLVPPEEEHNYDEYVQTLLAKGFINPDEWLDFGGLGTIPAEEYFG 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 254 AAVWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYKKLEEYLLSRDEEDRLELV 333
Cdd:COG3072  250 AGLWQLYKGIDSPYKSVLKLLLLEAYSSEYPNTQLLSLEFKQAVYAGELDLDELDPYVMMLRRVTRYLLERNDLKRLELV 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 334 RRCFYFKVNQKLSRKD-NVPYDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAVLVKELTYTYQFLSSFARQ 412
Cdd:COG3072  330 RRCFYLKVNEKLSRPPrERSKSWRRELLERLVREWGWSEERLALLDNRAQWKIEQVREERNELVDELMQSYRNLIQFARR 409
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 413 HAQLAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQRGREG-GWALLSsgGDSDSRDPSSMVA 491
Cdd:COG3072  410 NNISSSISPQDIGILGRKLYAAFERLPGKVTLINPGISPDLSEENLTFIQVPEGRANRaGWYLYN--QSLTPADIIGRQP 487
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 492 LKRSRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALPASkILETDIEELGRAVKVLESVLVVNLG 571
Cdd:COG3072  488 LKYSRSLVELVAWCYFNGLLTASTRLHLHPGGSDLDEYELQQLVADLRQHFPVP-LPAPSNEALSRPCEIRHLALFINLG 566
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 572 HDPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCLSNYFRMMPPSKgAAPPTPT 651
Cdd:COG3072  567 VDPTAHLSRRGIHFDSSRSDALSFGGARENLVGSIDLVYRNSWNEVRTLHFEGDDALLDALKTLLGKMHQDA-APPPSID 645
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 652 VLCYTQNHAITIRQRVERLFDDLVECFYGAREKQNNRFIFCVQRDYYVLYFEDDVMRYQRISDYGELLRYLSKGRQSFGQ 731
Cdd:COG3072  646 VFCYSQTRRGAIANRVEQLFNECISLRLGGTRQPNRRYLLRVAGQYYGLFFERRGVSVQKLENAVDLYRALSENKLSYSP 725
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 732 VTMDPNVISDK-LLALVFKFNKPGMVQFFYKRESGGnAEVYVVDENGSLFCQKHEAADEACLLGHYSRFFDTVLQRQLFQ 810
Cdd:COG3072  726 LVLDRHALEDHpLPPVIDSFASEGLIQFFFEDNGDG-FNIYILDENNSLEIYRQCEGDKEELLRPLNRFYRSSQDRRTYG 804
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 811 IIGQGeegkeAIEVEYYSVGRDRQGQYQVSRRAPHDSGKRG-YTSIQVIASREDasGSAFTIYCDEKEFSSLEYGSNLFT 889
Cdd:COG3072  805 SSFIN-----FNLPQFYQIVRNDGGELQVEPFRSPLAASDAnYYEVQAIGDEGD--DSLFEFYCDCQEFESLELEGDLLL 877
                        890       900       910       920       930
                 ....*....|....*....|....*....|....*....|....*....|..
gi 954626996 890 EIAVNILAKRKSRRTYPVYITDIDLTPDMFADYPAGHVPVVEFLNYKKNIEA 941
Cdd:COG3072  878 VAAVAILLRRRRRRPYPYYITDDDLLSALELDEQLEQQTVQTLQYLKYLEAL 929
cyaA PRK09450
class I adenylate cyclase;
19-811 0e+00

class I adenylate cyclase;


Pssm-ID: 236522 [Multi-domain]  Cd Length: 830  Bit Score: 870.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  19 RKRFITLNRQRLQRGEECMRSNQRDFLDFLPLLFHINHPSLPGYVSKLTPSGICDYTPTQRALDAAKKYIHRFDYRNRAL 98
Cdd:PRK09450   9 KQRLDALNQLRLARALAALSPAFQQVLSLLPLLLHVNHPLLPGYVSGNTPAGICNFTPDETQLAYLQRLELSFGYSVQDP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  99 PRYD--ILSMFLMGSSGTIAYSRKSDFDIWLCHQHDIPADRLAELQQKASLIEQWADEQGLEVHFFLMDAEDFRQGKI-V 175
Cdd:PRK09450  89 PKGElpITGLYTMGSTGSIGQSESSDLDIWVCHRPWLDAEERQLLQRKCSLLEQWAASLGVEVNFFLMDEERFRHNESgS 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 176 DLSSESSGTAQYYLLLEEFYRTSLLLAGRFPVWWLVPVEEEENYAAYVDNLYQSRLVNESEVIDFGGIPTLPAEEFFGAA 255
Cdd:PRK09450 169 ALGGEDCGSTQHILLLDEFYRTAIRLAGKRPLWWLVPVEEEEHYDDYVMTLYSKGFLNPNEWLDLGGLSSLPAEEYFGAS 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 256 VWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYKKLEEYLLSRDEEDRLELVRR 335
Cdd:PRK09450 249 LWQLYKGIDSPYKSVLKLLLLEAYSSEYPNTQLLSLDFKQRLLAGEIDSDGLDPYCLMLERVTRYLTAINDPTRLELVRR 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 336 CFYFKVNQKLSRKDNVPyDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAVLVKELTYTYQFLSSFARQHAQ 415
Cdd:PRK09450 329 CFYLKVGEKLSRERACV-GWRRELLSQLVSEWGWDEERLALLDNRANWKIGQVREFHNELVDALMQSYRNLIRFARRNNL 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 416 LAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQ-RGREGGWALLSsgGDSDSRDPSSMVALKR 494
Cdd:PRK09450 408 SSSISPQDIGILTRKLYAAFERLPGKVTLLNPQISPDLSEPDLTFIEVPPgRANRSGWYLYN--QAPDPDSIIGHQPLEY 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 495 SRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALP--ASKIletDIEELGRAVKVLESVLVVNLGH 572
Cdd:PRK09450 486 NRYLNKLVAWAYFNGLLTSSTRLHLKGNGSDLDLAKLQELVADLRQHFPlrLPAP---TPQALLQPCEIRHLLIIVNLEV 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 573 DPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCLSNYFRMMPPSkGAAPPTPTV 652
Cdd:PRK09450 563 DPTAHLRGQVVHFDFRNLDVFSFGGEQENLVGSVDLIYRNSWNEVRTLHFEGEQALLDALKTILGKMHQD-AAPPPSVEV 641
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996 653 LCYTQNHAITIRQRVERLFDDLVECFYGAREKQnNRFIFCVQRDYYVLYFEDDVMRYQRISDYGELLRYLSKGRQSFGQV 732
Cdd:PRK09450 642 FCYSQHLRGLIRTRVQQLVSECIELRLGSTRQE-PGKALRVAGQTWGLFFERLGVSVQKLENAVEFYGALSENKLHGLPV 720
                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 954626996 733 TMDPNviSDKLLALVFKFNKPGMVQFFYkRESGGNAEVYVVDENGSLFCQKHEAADEACLLGHYSRFFDTVLQRQLFQI 811
Cdd:PRK09450 721 QLDTN--FLKLPAVVDGFASEGIIQFFF-EDNEDGFNVYILDESNRLEHYHHCEGSKEELVRDVSRFYSSSHDRFTYGS 796
Adenylate_cycl pfam01295
Adenylate cyclase, class-I;
236-817 3.74e-137

Adenylate cyclase, class-I;


Pssm-ID: 426186  Cd Length: 601  Bit Score: 423.59  E-value: 3.74e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  236 EVIDFGGIPTLPAEEFFGAAVWQLFKGIDSPHKSLLKLLLMEVYAAEYPQIDLLCLRFKKSIFDGENDLDKLDPYLMLYK 315
Cdd:pfam01295   1 DWLDLGGLSALPAEEYFGASLWQLYKGIDSPYKAVLKILLLEAYSSEYPNTELLSSQFKRRLLAGDFTSYHLDPYLLMLE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  316 KLEEYLLSRDEEDRLELVRRCFYFKVNQKLSRKD-NVPYDWRRDLLRSMTNAWGWEDEYLAVMDRRQNWKIKQVLSERAV 394
Cdd:pfam01295  81 RVTDYLTKINDFKRLDLVRRCFYLKAGEGLSRLQpNGAKDWRRDKLQELVQQWHWSDELIQTLDNRRHWKVGQVKWANNQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  395 LVKELTYTYQFLSSFARQHAQLAAINQHDLNALGRKLYAAFERKTGKVEIVNRGISQDVFEPLLTLYQIRQ-RGREGGWA 473
Cdd:pfam01295 161 LLELLMLSYRNLIQFARKHNISESISPEDIGILTRKLYTAFEELPGKVTLLNPLISPDLSEPDLTFIEVPEgRSNKAGWY 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  474 LLSSGgdSDSRDPSSMVALKRSRHVIEALAWGYFNGLIKGSSVVKVIKHASDLETRQLEECVRSLEKALPaSKILETDIE 553
Cdd:pfam01295 241 LYNQP--PDPADLIGRRPLEYAKYLSKLVAWAYFNGLLTESTRLHLVSQGVDLTSDKLSQFVTDLRLSFP-VRAPKPTNQ 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  554 ELGRAVKVLESVLVVNLGHDPMVELRRSGAHLASNRTDAFSYGGMYGSLIGSVDQIILTSWKEVITSHFEAAAGMLDCL- 632
Cdd:pfam01295 318 DLSHPCEIRHLVIFINLEQDPTTHWSGQEVMVDIQNADLFSFGRSQENLVGSVDLIYRNSWNEIRTLHFEGENALLKALk 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  633 --SNYFRmmppsKGAAPP-TPTVLCYTQNHAITIRQRVERLFDDLVECFYGAREKQNNRFIFCVQRDYYVLYFEDDVMRY 709
Cdd:pfam01295 398 tiLNKIH-----RDAAPPeSIDVFCYSRRLRSQLRNAVKQLLNRCIELRLGTIQSRTQVKPLRIGGKNYGLFFERRGVSV 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996  710 QRISDYGELLRYLSKGRQSFGQVTMDPNVISDKLLALVFKFNKPGMVQFFYkRESGGNAEVYVVDENGSLFCQKHEAADE 789
Cdd:pfam01295 473 QDLENAVDFYGQISRNKLVELPRPELGDDPFLHIPAIIDAFASEGLIQFFF-EDNEDGFNVYILDEKNELEIYHQCDGSK 551
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 954626996  790 ACLLGHYSRFFDTVLQR-------------QLFQIIGQGEE 817
Cdd:pfam01295 552 DELVNEVNRFYASSESRkntnpafinfnlpQFYQLVRVNGE 592
Adenyl_cycl_N pfam12633
Adenylate cyclase NT domain;
14-209 2.12e-89

Adenylate cyclase NT domain;


Pssm-ID: 432684 [Multi-domain]  Cd Length: 198  Bit Score: 283.30  E-value: 2.12e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996   14 DVDAVRKRFITLNRQRLQRGEECMRSNQRDFLDFLPLLFHINHPSLPGYVSKLTPSGICDYTPTQRALDAAKKYIHRFDY 93
Cdd:pfam12633   1 DLETLRQRFDALNQLRLERALAALSPRQQQVLRLLPLLLHVNHPLLPGYVSGDTPCGIANFEPSKFQLALLDRLFRSFTY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 954626996   94 RNRALP--RYDILSMFLMGSSGTIAYSRKSDFDIWLCHQHDIPADRLAELQQKASLIEQWADEQGLEVHFFLMDAEDFRQ 171
Cdd:pfam12633  81 KETKTDisDPPILGLYLMGSTGSIAQSASSDLDIWVCHRPGLDAEELELLQRKCQLIEQWAAQFGVEVHFFLMDPERFRS 160
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 954626996  172 GKIVDLSSESSGTAQYYLLLEEFYRTSLLLAGRFPVWW 209
Cdd:pfam12633 161 NRSSSLTEESSGSAQHLLLLDEFYRTAIRLAGKRPLWW 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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