NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|937521145|gb|ALI41631|]
View 

AraC family transcriptional regulator [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
152-233 1.37e-28

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 103.79  E-value: 1.37e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145   152 QWHLKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTP 230
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ...
gi 937521145   231 SHY 233
Cdd:smart00342  81 SEY 83
PRK09940 super family cl42915
transcriptional regulator YdeO; Provisional
 1-230 2.40e-28

transcriptional regulator YdeO; Provisional


The actual alignment was detected with superfamily member PRK09940:

Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 108.25  E-value: 2.40e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145   1 MDYVCSVVFICQSFDLIINRRVISFKKNSLFIVSDKIRRELPVCPSKLRIVDIDKKTCLSFFIDVNNE-----LPGKFTL 75
Cdd:PRK09940   1 MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKKYLQCTNIQtvtvpVPAKFLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  76 DKNgyiaeeePPLSLVFSLFEGIKIADSHSLWLKERLCISLLAMFKKRESVNSFILTNINTFTCKITGIISFNIERQWHL 155
Cdd:PRK09940  81 ASN-------VPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 937521145 156 KDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMRYAKKLITSNSySINVVAQKCGYNSTSYFICAFKDYYGVTP 230
Cdd:PRK09940 154 KDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEG-SVNKIAEQCGYASTSYFIYAFRKHFGNSP 227
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
152-233 1.37e-28

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 103.79  E-value: 1.37e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145   152 QWHLKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTP 230
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ...
gi 937521145   231 SHY 233
Cdd:smart00342  81 SEY 83
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 1-230 2.40e-28

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 108.25  E-value: 2.40e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145   1 MDYVCSVVFICQSFDLIINRRVISFKKNSLFIVSDKIRRELPVCPSKLRIVDIDKKTCLSFFIDVNNE-----LPGKFTL 75
Cdd:PRK09940   1 MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKKYLQCTNIQtvtvpVPAKFLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  76 DKNgyiaeeePPLSLVFSLFEGIKIADSHSLWLKERLCISLLAMFKKRESVNSFILTNINTFTCKITGIISFNIERQWHL 155
Cdd:PRK09940  81 ASN-------VPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 937521145 156 KDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMRYAKKLITSNSySINVVAQKCGYNSTSYFICAFKDYYGVTP 230
Cdd:PRK09940 154 KDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEG-SVNKIAEQCGYASTSYFIYAFRKHFGNSP 227
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 109-236 6.17e-25

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 99.61  E-value: 6.17e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 109 KERLCISLLAMFKKRESVNSFILT----NINTFTCKItgiISFNIERQWHLKDIAELIYTSESLIKKRLRDEGTSFTEIL 184
Cdd:PRK09978 114 KRALIFALLSVFLEDEHFIPLLLNvlqpNMRTRVCTV---INNNIAHEWTLARIASELLMSPSLLKKKLREEETSYSQLL 190

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 937521145 185 RDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFEK 236
Cdd:PRK09978 191 TECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQER 242
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
155-233 2.08e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 89.84  E-value: 2.08e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 155 LKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHY 233
Cdd:COG2207  171 LEELARELGLSPRTLSRLFKEEtGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEY 250
HTH_18 pfam12833
Helix-turn-helix domain;
158-236 5.09e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 70.70  E-value: 5.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  158 IAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNS-YSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFE 235
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLEDTgLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 937521145  236 K 236
Cdd:pfam12833  81 R 81
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
152-233 1.37e-28

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 103.79  E-value: 1.37e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145   152 QWHLKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTP 230
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ...
gi 937521145   231 SHY 233
Cdd:smart00342  81 SEY 83
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 1-230 2.40e-28

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 108.25  E-value: 2.40e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145   1 MDYVCSVVFICQSFDLIINRRVISFKKNSLFIVSDKIRRELPVCPSKLRIVDIDKKTCLSFFIDVNNE-----LPGKFTL 75
Cdd:PRK09940   1 MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKKYLQCTNIQtvtvpVPAKFLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  76 DKNgyiaeeePPLSLVFSLFEGIKIADSHSLWLKERLCISLLAMFKKRESVNSFILTNINTFTCKITGIISFNIERQWHL 155
Cdd:PRK09940  81 ASN-------VPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 937521145 156 KDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMRYAKKLITSNSySINVVAQKCGYNSTSYFICAFKDYYGVTP 230
Cdd:PRK09940 154 KDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEG-SVNKIAEQCGYASTSYFIYAFRKHFGNSP 227
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 109-236 6.17e-25

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 99.61  E-value: 6.17e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 109 KERLCISLLAMFKKRESVNSFILT----NINTFTCKItgiISFNIERQWHLKDIAELIYTSESLIKKRLRDEGTSFTEIL 184
Cdd:PRK09978 114 KRALIFALLSVFLEDEHFIPLLLNvlqpNMRTRVCTV---INNNIAHEWTLARIASELLMSPSLLKKKLREEETSYSQLL 190

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 937521145 185 RDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFEK 236
Cdd:PRK09978 191 TECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQER 242
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 140-235 1.46e-24

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 99.30  E-value: 1.46e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 140 KITGIISFNIERQWHLKDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFI 219
Cdd:PRK15185 210 RVYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYFI 289

                         90
                 ....*....|....*.
gi 937521145 220 CAFKDYYGVTPSHYFE 235
Cdd:PRK15185 290 QCFKKYFKTTPSTFIK 305
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 56-234 1.23e-22

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 93.59  E-value: 1.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  56 KTCLSFFIDVNNELPGKFTLDKNGYI-AEEEPPLSLVFSLFEGIKIADSHSLWLKERLCISLLAMF-KKRESVNSFILTN 133
Cdd:PRK15186  99 KNAYNFFLYEHADFSAPLTKPTTKHLlAPIETGVARVFNLLHSSNKSQKLSQDKKEYLIRFLLSEFiYEPEAFALFRELS 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 134 INTFTCKITGIISFNIERQWHLKDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYN 213
Cdd:PRK15186 179 QNTLAENIYNIIISDISRKWALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGYD 258

                        170       180
                 ....*....|....*....|.
gi 937521145 214 STSYFICAFKDYYGVTPSHYF 234
Cdd:PRK15186 259 SASYFTCVFKKHFKTTPSEFL 279
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
155-233 2.08e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 89.84  E-value: 2.08e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 155 LKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHY 233
Cdd:COG2207  171 LEELARELGLSPRTLSRLFKEEtGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEY 250
HTH_18 pfam12833
Helix-turn-helix domain;
158-236 5.09e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 70.70  E-value: 5.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  158 IAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNS-YSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFE 235
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLEDTgLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 937521145  236 K 236
Cdd:pfam12833  81 R 81
PRK15044 PRK15044
transcriptional regulator SirC; Provisional
 140-237 8.76e-13

transcriptional regulator SirC; Provisional


Pssm-ID: 185004 [Multi-domain]  Cd Length: 295  Bit Score: 66.60  E-value: 8.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 140 KITGIISFNIERQWHLKDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFI 219
Cdd:PRK15044 196 KVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFI 275

                         90
                 ....*....|....*...
gi 937521145 220 CAFKDYYGVTPSHYFEKI 237
Cdd:PRK15044 276 AIFKRHFKITPLSFMRTM 293
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 148-233 1.04e-11

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 63.64  E-value: 1.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 148 NIERQWHLKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYY 226
Cdd:COG4977  222 NLEEPLSVDELARRAGMSPRTLERRFRAAtGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFRRRF 301


                 ....*..
gi 937521145 227 GVTPSHY 233
Cdd:COG4977  302 GVSPSAY 308
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 148-233 2.04e-09

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 56.99  E-value: 2.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 148 NIERQWHLKDIAELIYTSES----LIKKRLrdeGTSFTEILRDTRMRYAKKLITSNSySINVVAQKCGYNSTSYFICAFK 223
Cdd:COG2169   96 GAEDRPSLEDLAARLGLSPRhlrrLFKAHT---GVTPKAYARARRLLRARQLLQTGL-SVTDAAYAAGFGSLSRFYEAFK 171

                         90
                 ....*....|
gi 937521145 224 DYYGVTPSHY 233
Cdd:COG2169  172 KLLGMTPSAY 181
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
102-233 2.64e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 50.44  E-value: 2.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 102 DSHSLWLKERLCISLLAMFKK-RESVNSFILTNINTFTCKITGIISFNIERQWHLKDIAELIYTSESLIKKRLRDE-GTS 179
Cdd:PRK13502 141 DPLANEMAELLFGQLVMTLKRhRYATDDLPATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQtGMT 220

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 937521145 180 FTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHY 233
Cdd:PRK13502 221 INQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQW 274
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
71-233 9.97e-07

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 48.82  E-value: 9.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145  71 GKFTLDKNGYIAEEEpplslvfSLFEGIKIADSHSLWLKERLCISLL------AMFKKRESVNSFILTNINTfTCKItgi 144
Cdd:PRK10572 123 GRLRIPDEALQPEFS-------DLFGQIEQAGQSEGRYSELLAMNLLerlllrCMEAIPESLHPPMDPRVRE-ACQY--- 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 145 ISFNIERQWHLKDIAELIYTSESLIKKRLRDE-GTSfteILR---DTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFIC 220
Cdd:PRK10572 192 ISDHLASEFDIESVAQHVCLSPSRLAHLFRQQlGIS---VLRwreDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSR 268

                        170
                 ....*....|...
gi 937521145 221 AFKDYYGVTPSHY 233
Cdd:PRK10572 269 VFKKCTGASPSEF 281
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
148-238 6.51e-06

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 46.05  E-value: 6.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 148 NIERQWHLKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYY 226
Cdd:PRK13501 188 SLGAYFDMADFCHKNQLVERSLKQLFRQQtGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSAVFTREA 267

                         90
                 ....*....|..
gi 937521145 227 GVTPSHYFEKII 238
Cdd:PRK13501 268 GMTPRDYRQRFI 279
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
116-233 1.29e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 45.48  E-value: 1.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 116 LLAMFKKRESVNSFILTNINTFTCKITGIISFNIERQWHLKDIAELIYTSESLIKKRLRDE-GTSFTEILRDTRMRYAKK 194
Cdd:PRK13500 186 VMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQtGMTINQYLRQVRVCHAQY 265

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 937521145 195 LITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHY 233
Cdd:PRK13500 266 LLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQW 304
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 182-237 1.86e-05

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 44.75  E-value: 1.86e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 937521145 182 EILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFEKI 237
Cdd:PRK10296 219 QIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSYRKKL 274
ftrA PRK09393
transcriptional activator FtrA; Provisional
 148-233 2.01e-04

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 41.87  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937521145 148 NIERQWHLKDIAELIYTSESLIKKRLRD-EGTSFTEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYY 226
Cdd:PRK09393 230 HLAEPHTVASLAARAAMSPRTFLRRFEAaTGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEESLRHHFRRRA 309


                 ....*..
gi 937521145 227 GVTPSHY 233
Cdd:PRK09393 310 ATSPAAY 316
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 197-233 1.30e-03

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 35.59  E-value: 1.30e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 937521145  197 TSNSYSINVVAQKCGYnSTSYFICAFKDYYGVTPSHY 233
Cdd:pfam00165   5 LSTNLTIADIADELGF-SRSYFSRLFKKYTGVTPSQY 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH