|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
11-689 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 736.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 11 WLKKKWRRYQGGRWFIVITLLVILIISALGTLEAKTTDVSDLKARLQQSTIIYDENNNEAGSLAGHKGTYVELDAISPHV 90
Cdd:NF038276 29 PIRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALKATTVIYDKDGKEAGSLSGQKGTYVELDAISDDL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 91 VDAVIATEDRRFYQEYGFSVPGMVRGGVTtvlnkvrgVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDY 170
Cdd:NF038276 109 ENAVIATEDRSFYKNSGINYKRFFLAILT--------AGRFGGGSTITQQLAKNAYLSQDQTIKRKAKEFFLALELTKKY 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 171 SKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMVNTDK 250
Cdd:NF038276 181 SKKEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIYNPLYSIENATNRRDTVLQNMVDAGK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 251 LKQEDADTLKmnAVGASDHDSDN-----STYNYPSYFDAVINEAINRYDISETKLLNDGYQIYTSLNQQDQENLQNNYEN 325
Cdd:NF038276 261 IDQAQADEAA--AVDMGSRLADTyegksDDYRYPSYFDAVINEAISKYGLSEKDIVNNGYKIYTELDQNYQAGMQVTFDN 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 326 PNLDPL---NGQ-AQAASVVMDAQTGGVRAVVG---GRGEHVFRGFNRATQMKRSPGSTIKPIVDYAPALSRGFGIESKL 398
Cdd:NF038276 339 TSLFPVseyDGTsAQSASVALDPKTGGVRGLVGrvnSTENATFRSFNYATQSKRSPGSTIKPLVVYSPAVASGWSIDKEL 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 399 KNEVTSFGSnrYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSVTEDDNNLSLGLGGmekG- 477
Cdd:NF038276 419 PNTTQDYDG--YKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFGLNMDKVDKELGVALGG---Gv 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 478 -TSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHGTGVSANPSGYKVA 556
Cdd:NF038276 494 tTNPLEMAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKRVISQSVADKMTSMMLGTFSNGTGVNANVYGYTMA 573
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 557 GKTGTTEvsgegsTQAN---ATDAWAVAYTPDVVVVTWNGFDKTNGEQNLPIMLSATAGPLMKATLEQVIPNTNQTPFTV 633
Cdd:NF038276 574 GKTGTTE------TDFNpdlSSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASYILPYTKGTEFTV 647
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917632667 634 Q------GIHEKISQAEEQEQNGLNKS--VNDIGTQIQDGADSVMRSV-ESG----ARKVWDGVKGLFG 689
Cdd:NF038276 648 EnayaqnGIAPVYTANETSTETSSESQdiIDDIRESAQNAVDSASKAVdDAGikekAKSLWDSIVDWFR 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
9-632 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 655.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 9 MAWLKKKWRRYQGGRWFIVITLLVILIISALGTLEAKTTDVSDL----KARLQQSTIIYDENNNEAGSLAGHKGTYVELD 84
Cdd:COG0744 1 MAKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPeeleDLALPQTSTIYDRDGTLIATLGDENREWVPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 85 AISPHVVDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAI 164
Cdd:COG0744 81 QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARA----LVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLAL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 165 QVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQN 244
Cdd:COG0744 157 KLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 245 MVNTDKLKQEDADTLKMNAVGASDHDSDNSTYNYPSYFDAVINEAINRYdiSETKLLNDGYQIYTSLNQQDQENLQNNYE 324
Cdd:COG0744 237 MVEQGYITQAEADAAKAEPLTLVPPPNGAAAGKYPYFVDYVRRELEELL--GEDDLYRGGLKIYTTLDPKLQKAAEKAVK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 325 NPNLDPLNGQAQAASVVMDAQTGGVRAVVGGRgEHVFRGFNRATQMKRSPGSTIKPIVdYAPALSRGFGIESKLKNEVTS 404
Cdd:COG0744 315 NVLPEGKPGGLQAALVVVDPKTGEVLAMVGGR-DYGKSQFNRATQAKRQPGSTFKPFV-YAAALEQGYTPATTVDDEPVT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 405 FGSNRYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSvTEDDNNLSLGLGGMEkgTSPLELA 484
Cdd:COG0744 393 FPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLALGTSE--VSPLEMA 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 485 QAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHGTGVSANPSGYKVAGKTGTTEv 564
Cdd:COG0744 470 SAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTTN- 548
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917632667 565 sgegstqaNATDAWAVAYTPDVVVVTWNGFDKTngeQNLPIMLSAT-AGPLMKATLEQVIPNTNQTPFT 632
Cdd:COG0744 549 --------DNRDAWFVGYTPQLVTAVWVGNDDN---SPMGYVTGGSlPAPIWRDFMEAALEGLPVEDFP 606
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
77-625 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 575.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 77 KGTYVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGVttvlNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRK 156
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAV----ANITSGRVLEGGSTITQQLAKNLYLTNERTITRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 157 VRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQN 236
Cdd:TIGR02074 77 IQEALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 237 RRNQVLQNMVNTDKLKQEDADTLKMNAVGASDHDSDNSTYNYPSYFDAVINEAINRYDiseTKLLNDGYQIYTSLNQQDQ 316
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKAPYFVDYVIQELEEEYG---EELYTGGLKIYTTLDLDAQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 317 ENLQNNYENP--NLDPLNG-QAQAASVVMDAQTGGVRAVVGGRGeHVFRGFNRATQMKRSPGSTIKPIVdYAPALSRGFG 393
Cdd:TIGR02074 234 KAAEKVLNTGlrVAGRRDGdDLQAALVAIDPDTGAVRALVGGRD-YGKSQFNRATQAKRQPGSTFKPFV-YAAALEKGLT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 394 IESKLKNEVTSFGSNR-YTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSvTEDDNNLSLGLG 472
Cdd:TIGR02074 312 PATIVNDEPITYNGNGpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGIT-SPLDPVLSLALG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 473 GMEkgTSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHGTGVSANPSG 552
Cdd:TIGR02074 391 TVE--VSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARLPG 468
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917632667 553 YKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVTWNGFDKtngeqNLPIMLSAT----AGPLMKATLEQVIPN 625
Cdd:TIGR02074 469 RPVAGKTGTTQ---------NWRDAWFVGYTPYYVTAVWVGYDD-----KKTLGKSGTggglAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
66-246 |
4.89e-84 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 262.46 E-value: 4.89e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 66 NNNEAGSLAGHKGTYVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNA 145
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARA----LLSNLRSGRIVQGGSTITQQLAKNL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 146 FLTQDQTLKRKVRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGY 225
Cdd:pfam00912 77 FLTPERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRY 156
|
170 180
....*....|....*....|.
gi 917632667 226 DPVAHPEAAQNRRNQVLQNMV 246
Cdd:pfam00912 157 NPLRNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
42-668 |
1.22e-60 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 218.46 E-value: 1.22e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 42 LEAKTTDVSDLK-ARLQQSTIIYDENNNEAGSLAGHKGTYVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGVTT 120
Cdd:PRK11636 29 IEPQLPDVATLKdVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 121 VLNKvrgvNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYF 200
Cdd:PRK11636 109 LFSG----HASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 201 GIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMVNTDKLKQEDADTLKMNAVGASDHdSDNSTYNYPS 280
Cdd:PRK11636 185 GKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYH-APEIAFSAPY 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 281 YFDAVINEAINRYDISEtklLNDGYQIYTS----LNQQDQENLQNNYEN------------------------------- 325
Cdd:PRK11636 264 LSEMVRQEMYNRYGENA---YEDGYRVYTTitrkVQQAAQQAVRNNVLDydmrhgyrgpanvlwkvgesawdnkkitdtl 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 326 ---PNLDPL------------------------------------------------------NGQ-------------A 335
Cdd:PRK11636 341 kalPTYGPLlpavvtsanpqeatamladgssvalpmegvrwarpyrsdtqqgptprkvtdvvqTGQqiwvrqvddawwlA 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 336 Q-----AASVVMDAQTGGVRAVVGGRGEHVFRgFNRATQMKRSPGSTIKPIVdYAPALSRGFGIESKLkNEV------TS 404
Cdd:PRK11636 421 QvpdvnSALVSINPQNGAVMALVGGFDFNQSK-FNRATQALRQVGSNIKPFL-YTAAMDKGLTLASML-NDVpisrwdAG 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 405 FGSNrYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSVTEDDNNLSLGLGGmeKGTSPLELA 484
Cdd:PRK11636 498 AGSD-WRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGS--ASFTPMQVA 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 485 QAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDK----------------KTEVWSKSVADDMT--------------- 533
Cdd:PRK11636 575 RGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKvacpecdipviygdtqKSNVLENDDVENVAtsqeqqnssvpmpql 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 534 -------------------------------AMMLGVYTH----GTGVSA--NPSGYKVAGKTGTTEvsgegstqaNATD 576
Cdd:PRK11636 655 eqanqalvaqngaqeyaphvintplafliksALNTNIFGEpgwmGTGWRAgrDLKRRDIGGKTGTTN---------SSKD 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 577 AWAVAYTPDVVVVTWNGFD-------KTNGEQNLPIMLSA------TAGP----LMKATLEQViPNTNQTPftVQGI-HE 638
Cdd:PRK11636 726 AWFSGYGPGVVTSVWIGFDdhrrdlgRTTASGAIKDQISGyeggakSAQPawddYMKAALEGV-PEQPLTP--PPGIvTV 802
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 917632667 639 KISQAEEQEQNGLN--------------KSVNDIGTQIQDGADS 668
Cdd:PRK11636 803 NIDRSTGKLANGGNsreeyfiegtqptqQAVHEVGTTIIDNGET 846
|
|
| Peptidases_S8_10 |
cd07494 |
Peptidase S8 family domain, uncharacterized subfamily 10; This family is a member of the ... |
540-625 |
6.81e-03 |
|
Peptidase S8 family domain, uncharacterized subfamily 10; This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.
Pssm-ID: 173819 [Multi-domain] Cd Length: 298 Bit Score: 39.00 E-value: 6.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 540 YTHGTGVSANPsgYKVAGKTGTTEVSGEGSTQANATDAW--AVAYTPDVVVVTWnGFDKTNGEQNLPIMLSATAgPLMKA 617
Cdd:cd07494 61 NGHGTGESANL--FAIAPGAQFIGVKLGGPDLVNSVGAFkkAISLSPDIISNSW-GYDLRSPGTSWSRSLPNAL-KALAA 136
|
....*...
gi 917632667 618 TLEQVIPN 625
Cdd:cd07494 137 TLQDAVAR 144
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
11-689 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 736.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 11 WLKKKWRRYQGGRWFIVITLLVILIISALGTLEAKTTDVSDLKARLQQSTIIYDENNNEAGSLAGHKGTYVELDAISPHV 90
Cdd:NF038276 29 PIRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALKATTVIYDKDGKEAGSLSGQKGTYVELDAISDDL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 91 VDAVIATEDRRFYQEYGFSVPGMVRGGVTtvlnkvrgVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDY 170
Cdd:NF038276 109 ENAVIATEDRSFYKNSGINYKRFFLAILT--------AGRFGGGSTITQQLAKNAYLSQDQTIKRKAKEFFLALELTKKY 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 171 SKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMVNTDK 250
Cdd:NF038276 181 SKKEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIYNPLYSIENATNRRDTVLQNMVDAGK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 251 LKQEDADTLKmnAVGASDHDSDN-----STYNYPSYFDAVINEAINRYDISETKLLNDGYQIYTSLNQQDQENLQNNYEN 325
Cdd:NF038276 261 IDQAQADEAA--AVDMGSRLADTyegksDDYRYPSYFDAVINEAISKYGLSEKDIVNNGYKIYTELDQNYQAGMQVTFDN 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 326 PNLDPL---NGQ-AQAASVVMDAQTGGVRAVVG---GRGEHVFRGFNRATQMKRSPGSTIKPIVDYAPALSRGFGIESKL 398
Cdd:NF038276 339 TSLFPVseyDGTsAQSASVALDPKTGGVRGLVGrvnSTENATFRSFNYATQSKRSPGSTIKPLVVYSPAVASGWSIDKEL 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 399 KNEVTSFGSnrYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSVTEDDNNLSLGLGGmekG- 477
Cdd:NF038276 419 PNTTQDYDG--YKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFGLNMDKVDKELGVALGG---Gv 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 478 -TSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHGTGVSANPSGYKVA 556
Cdd:NF038276 494 tTNPLEMAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKRVISQSVADKMTSMMLGTFSNGTGVNANVYGYTMA 573
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 557 GKTGTTEvsgegsTQAN---ATDAWAVAYTPDVVVVTWNGFDKTNGEQNLPIMLSATAGPLMKATLEQVIPNTNQTPFTV 633
Cdd:NF038276 574 GKTGTTE------TDFNpdlSSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASYILPYTKGTEFTV 647
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917632667 634 Q------GIHEKISQAEEQEQNGLNKS--VNDIGTQIQDGADSVMRSV-ESG----ARKVWDGVKGLFG 689
Cdd:NF038276 648 EnayaqnGIAPVYTANETSTETSSESQdiIDDIRESAQNAVDSASKAVdDAGikekAKSLWDSIVDWFR 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
9-632 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 655.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 9 MAWLKKKWRRYQGGRWFIVITLLVILIISALGTLEAKTTDVSDL----KARLQQSTIIYDENNNEAGSLAGHKGTYVELD 84
Cdd:COG0744 1 MAKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPeeleDLALPQTSTIYDRDGTLIATLGDENREWVPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 85 AISPHVVDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAI 164
Cdd:COG0744 81 QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARA----LVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLAL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 165 QVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQN 244
Cdd:COG0744 157 KLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 245 MVNTDKLKQEDADTLKMNAVGASDHDSDNSTYNYPSYFDAVINEAINRYdiSETKLLNDGYQIYTSLNQQDQENLQNNYE 324
Cdd:COG0744 237 MVEQGYITQAEADAAKAEPLTLVPPPNGAAAGKYPYFVDYVRRELEELL--GEDDLYRGGLKIYTTLDPKLQKAAEKAVK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 325 NPNLDPLNGQAQAASVVMDAQTGGVRAVVGGRgEHVFRGFNRATQMKRSPGSTIKPIVdYAPALSRGFGIESKLKNEVTS 404
Cdd:COG0744 315 NVLPEGKPGGLQAALVVVDPKTGEVLAMVGGR-DYGKSQFNRATQAKRQPGSTFKPFV-YAAALEQGYTPATTVDDEPVT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 405 FGSNRYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSvTEDDNNLSLGLGGMEkgTSPLELA 484
Cdd:COG0744 393 FPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLALGTSE--VSPLEMA 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 485 QAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHGTGVSANPSGYKVAGKTGTTEv 564
Cdd:COG0744 470 SAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTTN- 548
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917632667 565 sgegstqaNATDAWAVAYTPDVVVVTWNGFDKTngeQNLPIMLSAT-AGPLMKATLEQVIPNTNQTPFT 632
Cdd:COG0744 549 --------DNRDAWFVGYTPQLVTAVWVGNDDN---SPMGYVTGGSlPAPIWRDFMEAALEGLPVEDFP 606
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
77-625 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 575.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 77 KGTYVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGVttvlNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRK 156
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAV----ANITSGRVLEGGSTITQQLAKNLYLTNERTITRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 157 VRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQN 236
Cdd:TIGR02074 77 IQEALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 237 RRNQVLQNMVNTDKLKQEDADTLKMNAVGASDHDSDNSTYNYPSYFDAVINEAINRYDiseTKLLNDGYQIYTSLNQQDQ 316
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKAPYFVDYVIQELEEEYG---EELYTGGLKIYTTLDLDAQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 317 ENLQNNYENP--NLDPLNG-QAQAASVVMDAQTGGVRAVVGGRGeHVFRGFNRATQMKRSPGSTIKPIVdYAPALSRGFG 393
Cdd:TIGR02074 234 KAAEKVLNTGlrVAGRRDGdDLQAALVAIDPDTGAVRALVGGRD-YGKSQFNRATQAKRQPGSTFKPFV-YAAALEKGLT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 394 IESKLKNEVTSFGSNR-YTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSvTEDDNNLSLGLG 472
Cdd:TIGR02074 312 PATIVNDEPITYNGNGpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGIT-SPLDPVLSLALG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 473 GMEkgTSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHGTGVSANPSG 552
Cdd:TIGR02074 391 TVE--VSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARLPG 468
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917632667 553 YKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVTWNGFDKtngeqNLPIMLSAT----AGPLMKATLEQVIPN 625
Cdd:TIGR02074 469 RPVAGKTGTTQ---------NWRDAWFVGYTPYYVTAVWVGYDD-----KKTLGKSGTggglAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
22-633 |
3.53e-152 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 460.40 E-value: 3.53e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 22 GRWFIVITLLVILIISALG----TLEAKTTDVSDLK-ARLQQSTIIYDENNNEAGSLAGHKGTYVELDAISPHVVDAVIA 96
Cdd:COG5009 5 KILLILLLLLLLLGALAVAglylYLSPDLPDVETLKdYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 97 TEDRRFYQEYGFSVPGMVRGGVTTVlnkVRGvNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDYSKDDIL 176
Cdd:COG5009 85 AEDKRFYEHPGVDPIGIARAAVVNL---RTG-RRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 177 TMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMVNTDKLKQEDA 256
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 257 DTLKMNAVGASDHdsDNSTYNYPSYF-DAVINEAINRYDisETKLLNDGYQIYTSLNQQDQEN----LQNNYEN------ 325
Cdd:COG5009 241 EAAKAEPLTARYH--GASAEVDAPYFaEMVRRELVERYG--EDALYTGGLKVYTTLDPRLQEAaekaLRDGLLAydrrhg 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 326 ----------------------PNLDPL------------------NG-------------------------------- 333
Cdd:COG5009 317 yrgpeahldlaeedwdealaevPDVGDLrpavvlevddksarvglrDGetgtlpleglkwarpyindnrrgpapksasdv 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 334 -----------------------QAQAASVVMDAQTGGVRAVVGGRGehvFR--GFNRATQMKRSPGSTIKPIVdYAPAL 388
Cdd:COG5009 397 lkpgdvirvrpvadggwrlrqipEVQGALVALDPHTGAVLALVGGFD---FEqsKFNRATQAKRQPGSSFKPFV-YAAAL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 389 SRGFGIESKLKNE----VTSFGSNRYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGlsVTED- 463
Cdd:COG5009 473 DNGYTPATIINDApivfDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFG--IYSKl 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 464 DNNLSLGLGGMEkgTSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHK---------------------DKKTE 522
Cdd:COG5009 551 PPNLSLALGSGE--VTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADparacedcdaaewdgaeprlpDPAEQ 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 523 VWSKSVADDMTAMMLGVYTHGTGVSANPSGYKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVTWNGFDK----TN 598
Cdd:COG5009 629 VIDPRTAYQMTSMLRGVVQRGTGRRARALGRDIAGKTGTTN---------DSKDAWFVGFTPDLVAGVWVGFDDprslGR 699
|
730 740 750
....*....|....*....|....*....|....*....
gi 917632667 599 GEQNlpimlSATAGPL----MKATLEQVIPntnqTPFTV 633
Cdd:COG5009 700 GETG-----GRAALPIwidfMKAALKDKPE----KPFPV 729
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
9-631 |
5.31e-102 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 329.10 E-value: 5.31e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 9 MAWLKKKWRRYQGGRWFIVITLLVILIISALGTLeakttdvsDLKARLQQSTIIYDENNNEAGSLAGHKGTY---VELDA 85
Cdd:COG4953 1 MKRARLRRRRLLALLLALLLLALALWALDRLFPL--------PLLFAVPYSTVVLDRDGTLLRAFLAADGQWrlpVPLDE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 86 ISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGVTTVLNKvRGVnaaAGGSTLTQQLVKnafLTQDQ--TLKRKVRELFLA 163
Cdd:COG4953 73 VSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSG-RIV---SGGSTLTMQVAR---LLEPRprTLSGKLRQILRA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 164 IQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQ 243
Cdd:COG4953 146 LQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 244 NMVNTDKLKQEDADTLKMNAVGAsdhdsdnSTYNYPSY---F-DAVINEAinrydisetkllNDGYQIYTSLN---QQDQ 316
Cdd:COG4953 226 RLAEAGVIDAEEAALALLEPVPA-------RRRPLPQLaphLaRRLLRQL------------PGGTRIRTTLDaglQRRL 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 317 ENLQNNYeNPNLDPlNGQAQAASVVMDAQTGGVRAVVGGRG----EHvfRGFNRATQMKRSPGSTIKPIVdYAPALSRGF 392
Cdd:COG4953 287 ERLVRRY-VRRLKQ-NGIHNAAVLVVDNRTGEVLAYVGSADffdaSR--QGQVDMVRALRSPGSTLKPFL-YGLALDQGL 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 393 gI--ESKLKNEVTSFGSnrYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSV---TEDDNNL 467
Cdd:COG4953 362 -IhpETLLADVPTSFGG--YRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLllpPAEHYGL 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 468 SLGLGGMEkgTSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVehkdkktevwSKSVADDMTAMMLGVY--THGTG 545
Cdd:COG4953 439 SLILGGAE--VTLEELVGLYAALARGGEARPLRLLAGEPASPGRRLL----------SPGAAWLVRDILSDVPrpDGAFG 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 546 VSANPSGYKVAGKTGTTevSGEgstqanaTDAWAVAYTPDVVVVTWNG-FDktnGEQNLPIMLSATAGPLMKATLEQVIP 624
Cdd:COG4953 507 WRALDSPPPIAWKTGTS--YGF-------RDAWAVGFTGRYTVGVWVGnPD---GTPVPGLTGAEAAAPLLFDIFDLLPA 574
|
....*..
gi 917632667 625 NTNQTPF 631
Cdd:COG4953 575 SRWPLPF 581
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
66-246 |
4.89e-84 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 262.46 E-value: 4.89e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 66 NNNEAGSLAGHKGTYVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNA 145
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARA----LLSNLRSGRIVQGGSTITQQLAKNL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 146 FLTQDQTLKRKVRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGY 225
Cdd:pfam00912 77 FLTPERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRY 156
|
170 180
....*....|....*....|.
gi 917632667 226 DPVAHPEAAQNRRNQVLQNMV 246
Cdd:pfam00912 157 NPLRNPERAKRRRNLVLDRMV 177
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
80-630 |
7.76e-82 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 274.29 E-value: 7.76e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 80 YVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRE 159
Cdd:TIGR02071 149 FVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRA----VWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 160 LFLAIQVEQDYSKDDILTMYLNNAYFG-RGA---WGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQ 235
Cdd:TIGR02071 225 AYMALILDARYSKDRILELYLNEVYLGqSGDdaiHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRAL 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 236 NRRNQVLQNMVNTDKLKQEDADTLKMNAVGASDHDSDNSTynYPSYFDAVINEAinRYDISETKLLNDGYQIYTSLNQQD 315
Cdd:TIGR02071 305 ERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQKKGGIISR--QPAFLQLVRREL--RQKLGDKVKDLSGLRIFTTLDPVS 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 316 QENLQNNYEN--------PNLDPLngqaQAASVVMDAQTGGVRAVVGGRgEHVFRGFNRATQMKRSPGSTIKPIVdYAPA 387
Cdd:TIGR02071 381 QSAAEQAVQEtipalkkkKKLPDL----EAAMVVTDRFTGEVRAMVGGS-DPQFAGFNRALQARRQIGSLVKPAV-YLTA 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 388 LSR--GFGIESKLKNEVTSF---GSNRYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSVTE 462
Cdd:TIGR02071 455 LSQpdKYRLNTWIEDQPLSIklsNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINKDE 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 463 DDNNLSLGLGGMEkgTSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTH 542
Cdd:TIGR02071 535 IPPVPSMLLGAIN--LTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQR 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 543 GTG--VSANPSGYKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVTWNGFDktngeQNLPIMLSATAGPLM--KAT 618
Cdd:TIGR02071 613 GTArsLGADFPSLSLAGKTGTTN---------DNRDSWFAGIDGKEVTIIWLGRD-----DNGPTKLTGASGALQvyARY 678
|
570
....*....|..
gi 917632667 619 LEQVIPNTNQTP 630
Cdd:TIGR02071 679 LSYQTPEPLLLV 690
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
50-614 |
4.60e-79 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 266.98 E-value: 4.60e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 50 SDLKARLQQSTIIYDENNNEAGSLAGHKGTY---VELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGVTTVLNKVR 126
Cdd:TIGR02073 2 PPLLFHRPSSTVVLDRHGTLLRALLANDGQWrlpVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 127 gvnaAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKD 206
Cdd:TIGR02073 82 ----VSGGSTLTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 207 LSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMVNTDKLKQEDADTLKMNAVGASDHdsdnstynyPSYFDAvi 286
Cdd:TIGR02073 158 LSLAEAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALPE---------PLPQLA-- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 287 neainrYDISEtKLLNDGYQIY----TSLN---QQDQENLQNNYENPNldPLNGQAQAASVVMDAQTGGVRAVVGGRGEH 359
Cdd:TIGR02073 227 ------PHFAL-KLLRARPEIAsvivSTLDadlQRRLEELARRYLSAL--RPRGISNLAILVVDNRSGAVLAYVGSADFF 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 360 VFRGFNR--ATQMKRSPGSTIKPIVdYAPALSRGF-GIESKLKNEVTSFGSnrYTPHNAGEVTSEPVPMYQALEMSYNIP 436
Cdd:TIGR02073 298 DDSNSGQvdGVRAPRSPGSTLKPFL-YALALDDGLlHPDSLLKDVPLRFGD--YAPENFDKTFHGPVPAREALARSLNIP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 437 AVWLLDQMGAKVGYDAAKKVGLSVTEDDN---NLSLGLGGmeKGTSPLELAQAYTSFANDGQMSEAHFITkiVDATgktv 513
Cdd:TIGR02073 375 AVRLLERVGPPRFADFLRQAGLNLLKPKSdyyGLSLALGG--AEITLQDLANLYAMLANQGLSGPLRFLQ--TDAK---- 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 514 vehKDKKTEVWSKsVADDMTAMMLGVYTH---GTGVSANPSGYKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVT 590
Cdd:TIGR02073 447 ---RPERERLLSP-GAAWIVLDILKDRPRpddTLPLSALPTRLPLAWKTGTSY---------GFRDAWAAGVSGRYTIGV 513
|
570 580
....*....|....*....|....
gi 917632667 591 WNGfdKTNGEQNLPIMLSATAGPL 614
Cdd:TIGR02073 514 WVG--NFDGKPNPGFFGAAAAAPL 535
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
42-668 |
1.22e-60 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 218.46 E-value: 1.22e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 42 LEAKTTDVSDLK-ARLQQSTIIYDENNNEAGSLAGHKGTYVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGVTT 120
Cdd:PRK11636 29 IEPQLPDVATLKdVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 121 VLNKvrgvNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYF 200
Cdd:PRK11636 109 LFSG----HASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 201 GIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMVNTDKLKQEDADTLKMNAVGASDHdSDNSTYNYPS 280
Cdd:PRK11636 185 GKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYH-APEIAFSAPY 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 281 YFDAVINEAINRYDISEtklLNDGYQIYTS----LNQQDQENLQNNYEN------------------------------- 325
Cdd:PRK11636 264 LSEMVRQEMYNRYGENA---YEDGYRVYTTitrkVQQAAQQAVRNNVLDydmrhgyrgpanvlwkvgesawdnkkitdtl 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 326 ---PNLDPL------------------------------------------------------NGQ-------------A 335
Cdd:PRK11636 341 kalPTYGPLlpavvtsanpqeatamladgssvalpmegvrwarpyrsdtqqgptprkvtdvvqTGQqiwvrqvddawwlA 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 336 Q-----AASVVMDAQTGGVRAVVGGRGEHVFRgFNRATQMKRSPGSTIKPIVdYAPALSRGFGIESKLkNEV------TS 404
Cdd:PRK11636 421 QvpdvnSALVSINPQNGAVMALVGGFDFNQSK-FNRATQALRQVGSNIKPFL-YTAAMDKGLTLASML-NDVpisrwdAG 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 405 FGSNrYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSVTEDDNNLSLGLGGmeKGTSPLELA 484
Cdd:PRK11636 498 AGSD-WRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGS--ASFTPMQVA 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 485 QAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDK----------------KTEVWSKSVADDMT--------------- 533
Cdd:PRK11636 575 RGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKvacpecdipviygdtqKSNVLENDDVENVAtsqeqqnssvpmpql 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 534 -------------------------------AMMLGVYTH----GTGVSA--NPSGYKVAGKTGTTEvsgegstqaNATD 576
Cdd:PRK11636 655 eqanqalvaqngaqeyaphvintplafliksALNTNIFGEpgwmGTGWRAgrDLKRRDIGGKTGTTN---------SSKD 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 577 AWAVAYTPDVVVVTWNGFD-------KTNGEQNLPIMLSA------TAGP----LMKATLEQViPNTNQTPftVQGI-HE 638
Cdd:PRK11636 726 AWFSGYGPGVVTSVWIGFDdhrrdlgRTTASGAIKDQISGyeggakSAQPawddYMKAALEGV-PEQPLTP--PPGIvTV 802
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 917632667 639 KISQAEEQEQNGLN--------------KSVNDIGTQIQDGADS 668
Cdd:PRK11636 803 NIDRSTGKLANGGNsreeyfiegtqptqQAVHEVGTTIIDNGET 846
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
91-630 |
6.24e-58 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 210.40 E-value: 6.24e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 91 VDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDY 170
Cdd:PRK09506 224 VDTLLATEDRHFYEHDGISLYSIGRA----VLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARY 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 171 SKDDILTMYLNNAYFGRGA----WGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNMV 246
Cdd:PRK09506 300 SKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQ 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 247 NTDKLKQEDADTLKMNAVGASDHDSDNSTynYPSYFDAVINEAinrydisETKL---LND--GYQIYTSLNQQDQENLQN 321
Cdd:PRK09506 380 QQQIIDQELYDMLSARPLGVQPKGGVISP--QPAFMQMVRQEL-------QAKLgdkVKDlsGVKIFTTLDPVSQDAAEK 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 322 NYEN--PNLDPLNGQA--QAASVVMDAQTGGVRAVVGGRGEHvFRGFNRATQMKRSPGSTIKPIVdYAPALSR--GFGIE 395
Cdd:PRK09506 451 AVEEgiPALKKQRKLSdlETAMVVVDRFSGEVRAMVGGSEPQ-FAGYNRAMQARRSIGSLAKPAT-YLTALSQpdKYRLN 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 396 SKLKNEVTSF---GSNRYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLldqmGAKVGYDAA----KKVGLSVTEDDNNLS 468
Cdd:PRK09506 529 TWIADAPISLrqpNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNL----GMALGLPAVtdtwIKLGVPKDQLNPVPA 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 469 LGLGGMekGTSPLELAQAYTSFANDGQMSEAHFITKIVDATGkTVVEHKDKKTEVWSKSVADDMTAM-MLGVYTHGTG-- 545
Cdd:PRK09506 605 MLLGAL--NLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDG-KVLYQSFPQAERAVPAQAAYLTLYtMQQVVQRGTGrq 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 546 VSANPSGYKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVTWNGFDktngeQNLPIMLSATAGPLM--KATLEqvi 623
Cdd:PRK09506 682 LGAKYPNLHLAGKTGTTN---------DLVDSWFAGIDGKEVTITWVGRD-----NNQPTKLYGASGAMTiyQRYLE--- 744
|
....*..
gi 917632667 624 pntNQTP 630
Cdd:PRK09506 745 ---NQTP 748
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
90-595 |
1.78e-57 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 208.16 E-value: 1.78e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 90 VVDAVIATEDRRFYQEYGFSVPGMVRGgvtTVLNKVRGvNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQD 169
Cdd:PRK14850 169 LIKTLLAIEDKYFYEHDGIHLSSIGRA---FLVNLMSG-HTIQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRF 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 170 YSKDDILTMYLNNAYFGRGA----WGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQVLQNM 245
Cdd:PRK14850 245 YSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLL 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 246 VNTDKLKQEDADTLKMNAVGAsdHDSDNSTYNYPSYFDAVINEAINRYDISETKLlnDGYQIYTSLN---QQDQEN---- 318
Cdd:PRK14850 325 YKQKVITRKLYKDLCSRPLNV--QSKGNIISSHPAFIQLVCEEFHKKIHYPFKNF--SGTKIFTTLDyisQNAAEQavki 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 319 ----LQNNYENPNLdplngqaQAASVVMDAQTGGVRAVVGGRGEHvFRGFNRATQMKRSPGSTIKPIVdYAPALSR---- 390
Cdd:PRK14850 401 gipiLKRKKRLKDL-------EVAMVIIDRFSGEVRALIGSSKPE-FNGYNRALKARRSIGSLSKPIT-YLTALSQpeky 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 391 -------GFGIESKLKNevtsfgSNRYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSVTED 463
Cdd:PRK14850 472 hlntwisDTPISIKLDN------GQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYI 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 464 DNNLSLGLGGMEkgTSPLELAQAYTSFANDGQMSEAHFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTHG 543
Cdd:PRK14850 546 TPLPSISLGAIN--LTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSG 623
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 917632667 544 TGVSANP--SGYKVAGKTGTTEvsgegstqaNATDAWAVAYTPDVVVVTWNGFD 595
Cdd:PRK14850 624 TAKSLGTifKEFSLAGKTGTTN---------NLVDSWFVGIDGKQVVITWIGRD 668
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
81-497 |
4.88e-39 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 154.47 E-value: 4.88e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 81 VELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGGvttvLNKVRGVNAAAGGSTLTQQlVKNAFLTQDQTLKRKVREL 160
Cdd:PRK11240 65 VTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAA----WQDLTSGRVISGGSTLTMQ-VARLLDPHPRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 161 FLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDPVAHPEAAQNRRNQ 240
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 241 VLQNMV--------NTDKLKQED-----------ADTLKMNAVGASDHDSDNSTynypsyFDAvineainrydisetkll 301
Cdd:PRK11240 220 VLERMAeqgvwsaeQVKESREEPvwlaprqmpqlAPLFARMMLGKSKSDKIVTT------LDA----------------- 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 302 ndgyqiytSLNQQDQENLQN-NYENPNldplngQAQAASVVMDAQTGGVRAVVGG-------RGEHVfrgfnratQMK-- 371
Cdd:PRK11240 277 --------GLQRRLEDLALNwKGRLPP------RSSLAMIVVDHTDMAVRGWVGSvdlnddsRFGHV--------DMVna 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 372 -RSPGSTIKPIVdYAPALSRGFgI--ESKLKNEVTSFGSnrYTPHNAGEVTSEPVPMYQALEMSYNIPAVWLLDQMGAKV 448
Cdd:PRK11240 335 iRSPGSVLKPFV-YGLALDDGL-IhpASLLQDVPRRTGD--YRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKR 410
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 917632667 449 GYDAAKKVGLSVT---EDDNNLSLGLGGmeKGTSPLELAQAYTSFANDGQMS 497
Cdd:PRK11240 411 FAAKLRNVGLPLYlpaGAEPNLSLILGG--AGARLEDMVAAYSAFARHGKAA 460
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
303-628 |
4.33e-37 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 146.51 E-value: 4.33e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 303 DGYQIYTSLNQ--QD--QENLQNNYENPNLDplngqaQAASVVMDAQTGGVRAVV----------GGRGEHVFRgfNRAT 368
Cdd:COG0768 217 PGKDLVLTIDSdlQKiaEEALKKAVEEYKAK------SGAVVVMDPKTGEILAMAsypsfdpnlfVGGPDEPLR--NRAV 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 369 QMKRSPGSTIKPIVdyapALSrgfGIESKLKNEVTSFGSNRY------TPHNAGEVTSEPVPMYQALEMSYNIPAVWLLD 442
Cdd:COG0768 289 QGTYEPGSTFKPFT----AAA---ALEEGVITPDTTFDCPGYyrvggrTIRDWDRGGHGTLTLTEALAKSSNVGFYKLAL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 443 QMGAKVGYDAAKKVGLsvtedDNNLSLGLGGMEKG-----------------------TSPLELAQAYTSFANDGQMSEA 499
Cdd:COG0768 362 RLGIDKLYDYLKKFGL-----GQKTGIDLPGEASGllpspkrwypgetatmsigqglsVTPLQLAQAYAAIANGGVLVKP 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 500 HFITKIVDATGKTVVEHKDKKTEVWSKSVADDMTAMMLGVYTH--GTGVSANPSGYKVAGKTGTTEVSGE--GSTQANAT 575
Cdd:COG0768 437 HLVKEIVDPDGEVVKEEPEVLRRVISPETAETVREGMEGVVNEpgGTARRAAIPGYRVAGKTGTAQVVDIgnGGYYKGRH 516
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 917632667 576 DAWAVAYTPD------VVVVTWNGFDKTNGeqnlpimlSATAGPLMKATLEQVIPNTNQ 628
Cdd:COG0768 517 IASFVGFAPAdnpryaVAVVVENPGGGAYG--------GTVAAPVFREIMEAYLRLLGP 567
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
23-255 |
9.59e-34 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 129.15 E-value: 9.59e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 23 RWFIVITLLVILIISALGTLEAKTtDVSDLKARLQQSTIIYDENNNEagslaghkgtyveldaispHVVDAVIATEDRRF 102
Cdd:PRK13481 10 KILLTILIIIALFIGIMYFLSTRD-NVDELRKIENKSSFVSADNMPE-------------------YVKGAFISMEDERF 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 103 YQEYGFSVPGMVRGGVTTVLNKvrgvnAAAGGSTLTQQLVKNAFLTQDQTLKRKVRELFLAIQVEQDYSKDDILTMYLNN 182
Cdd:PRK13481 70 YKHHGFDLKGTTRALFSTISDR-----DVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQYSKNEILSFYLNN 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 183 AYFGRGAWGVQDAAQKYFGI-------DAKDLSVDQAAMIAGMLQSPGGYDPvahPEAAQNRRNQVlqnMVNTDKLKQED 255
Cdd:PRK13481 145 IYFGDNQYTLEGAANHYFGTtvnknstTMSHITVLQSAILASKVNAPSVYNI---NDMSENFTQRV---STNLEKMKQQN 218
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
80-244 |
3.82e-33 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 127.19 E-value: 3.82e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 80 YVELDAISPHVVDAVIATEDRRFYQEYGFSVPGMVRGgvttVLNKVRGVNAAAGGSTLTQQLVKNAFLTQDQTLKRKVRE 159
Cdd:TIGR02070 57 WRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDA----LEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLE 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 160 LFLAIQVEQDYSKDDILTMYLNNAYFGRGAWGVQDAAQKYFGIDAKDLSVDQAAMIAGMLQSPGGYDpVAHPEAAQNRRN 239
Cdd:TIGR02070 133 AWATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYD-ENRPGPYVRRKA 211
|
....*
gi 917632667 240 QVLQN 244
Cdd:TIGR02070 212 TWILK 216
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
340-620 |
8.06e-30 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 119.83 E-value: 8.06e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 340 VVMDAQTGGVRAVVGGRGEHVFRGF----NRATQMKRSPGSTIKPIVdYAPALSRG-------FGIESKLKNEVTSFGSn 408
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKPSYDPNGFIgplrNRAVTSRYEPGSTFKPFT-ALAALDNGvlkpdetIFDWPGKQQGGKSIGD- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 409 rYTPHNAGEVTsepvpMYQALEMSYNIPAVWLLDQMGAKVGYDAAKKVGLSV--------------TEDDNNLSLGLGGM 474
Cdd:pfam00905 82 -WNQDQVGIGT-----LRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNktgiglpgenagylTPYWLEGATASFGI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 475 EKGTSPLELAQAYTSFANDGQMSEAHFITKIVDatgkTVVEHKDKKTEVwSKSVADDMTAMMLGVYTHGTGVSANPS-GY 553
Cdd:pfam00905 156 GLTITPLQQAQAYAAIANGGKLVPPHLVKSIED----KVDPKVLNKLPI-SKSTAEKVKDMLRLVVNDGTGTGTAAVpGY 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917632667 554 KVAGKTGTTEVSGE--GSTQANATDAWAVAYTPD-----VVVVTWNGFDKTNGeqnlpimlSATAGPLMKATLE 620
Cdd:pfam00905 231 KVAGKTGTAQVAGPkgGGYYDGAQIGWFVGYAPAdnpkyAFAVLIDDPKRYYG--------GKVAAPIFKDILE 296
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
333-621 |
2.42e-20 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 95.28 E-value: 2.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 333 GQAQAASVVMDAQTGGVRAVV-----------GG---------RGEHVFRGFNRATQMKRSPGSTIKPIVdyapALSrgf 392
Cdd:TIGR03423 245 GGRRGAVVVMDPRTGEILAMVstpsfdpnlfvDGisskdykalLNDPDRPLLNRAIQGVYPPGSTFKPVV----ALA--- 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 393 GIESKLKNEVTS--------FGSNRYTPHNAGEVTSepVPMYQALEMS-----YnipavwlldQMGAKVGYDA----AKK 455
Cdd:TIGR03423 318 ALEEGVITPETRiycpgyfqLGGRRFRCWKRGGHGR--VDLRKAIEEScdvyfY---------QLALRLGIDKiaeyAKR 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 456 VGLSVT-----------------------------EDDNNLSLGLGGMekGTSPLELAQAYTSFANDGQMSEAHFITKIV 506
Cdd:TIGR03423 387 FGFGQKtgidlpgeksglvpsrewkrkrfgqpwypGDTLNVSIGQGYV--LVTPLQLAVATAALANGGKLYKPHLVKSIE 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 507 DATGKTVVEHKDKKTEVW--SKSVADDMTAMMLGVYTH--GTG-VSANPSGYKVAGKTGTTEV-SGEGSTQANATD---- 576
Cdd:TIGR03423 465 DPDGGVVRRTEPEVLRPLpiSPENLDVVREGMRDVVNGpgGTArRARLGLPYKMAGKTGTAQVvSLKQGEKYDAEQiper 544
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 917632667 577 ----AWAVAYTPD-----VVVVTWNgfdktNGEQNlpimlSATAGPLMKATLEQ 621
Cdd:TIGR03423 545 lrdhALFVAFAPYdnpkiAVAVIVE-----HGGGG-----SSAAAPIARKIMDA 588
|
|
| Peptidases_S8_10 |
cd07494 |
Peptidase S8 family domain, uncharacterized subfamily 10; This family is a member of the ... |
540-625 |
6.81e-03 |
|
Peptidase S8 family domain, uncharacterized subfamily 10; This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.
Pssm-ID: 173819 [Multi-domain] Cd Length: 298 Bit Score: 39.00 E-value: 6.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917632667 540 YTHGTGVSANPsgYKVAGKTGTTEVSGEGSTQANATDAW--AVAYTPDVVVVTWnGFDKTNGEQNLPIMLSATAgPLMKA 617
Cdd:cd07494 61 NGHGTGESANL--FAIAPGAQFIGVKLGGPDLVNSVGAFkkAISLSPDIISNSW-GYDLRSPGTSWSRSLPNAL-KALAA 136
|
....*...
gi 917632667 618 TLEQVIPN 625
Cdd:cd07494 137 TLQDAVAR 144
|
|
| |
