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Conserved domains on  [gi|440216408|gb|AGB95062|]
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uncharacterized protein Dmel_CG10803, isoform E [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TROVE super family cl05344
TROVE domain; This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding ...
197-394 9.28e-07

TROVE domain; This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-binding.


The actual alignment was detected with superfamily member pfam05731:

Pssm-ID: 461724  Cd Length: 361  Bit Score: 51.23  E-value: 9.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440216408  197 SDLLLFVQLVKRVQKLLERK-TPFNRTVRKAVLNWYGTKSLDRL-LHFWSIGDGNRWpAHRDLLyRLHfRHANFLPEIIA 274
Cdd:pfam05731 111 TDLFEVAEYCEELAEGDEKKlTGWGRCLRRAMTDWYTSKFAEFLaYQLTKYNTRKHW-SHKDPF-RLP-HPPKFSETSLE 187
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440216408  275 ALRLLSSSPKELSQWPDFLTPL----TSFRETIEGVVKLRLLTDPEQAI--SIVKKLSLSWEHVPFHLLHDPRLAHFLIP 348
Cdd:pfam05731 188 LKGLFRYATKEQRKFEKAYGAVpekkESKRLTLKKLVQRLHISEPAEHVqaLIGKRYRLTWEREPSLRGNSAEVWEELID 267
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 440216408  349 H-MSYEQLLQKWPRLSRL----NSRVRPFAEQLLDKKKLKASNVPPVRLLL 394
Cdd:pfam05731 268 SkLPMMAMLRNLCNLLRVgvsaRHHEDLVLQRLQNPKSVIHSRQHPFRFLN 318
 
Name Accession Description Interval E-value
TROVE pfam05731
TROVE domain; This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding ...
197-394 9.28e-07

TROVE domain; This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-binding.


Pssm-ID: 461724  Cd Length: 361  Bit Score: 51.23  E-value: 9.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440216408  197 SDLLLFVQLVKRVQKLLERK-TPFNRTVRKAVLNWYGTKSLDRL-LHFWSIGDGNRWpAHRDLLyRLHfRHANFLPEIIA 274
Cdd:pfam05731 111 TDLFEVAEYCEELAEGDEKKlTGWGRCLRRAMTDWYTSKFAEFLaYQLTKYNTRKHW-SHKDPF-RLP-HPPKFSETSLE 187
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440216408  275 ALRLLSSSPKELSQWPDFLTPL----TSFRETIEGVVKLRLLTDPEQAI--SIVKKLSLSWEHVPFHLLHDPRLAHFLIP 348
Cdd:pfam05731 188 LKGLFRYATKEQRKFEKAYGAVpekkESKRLTLKKLVQRLHISEPAEHVqaLIGKRYRLTWEREPSLRGNSAEVWEELID 267
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 440216408  349 H-MSYEQLLQKWPRLSRL----NSRVRPFAEQLLDKKKLKASNVPPVRLLL 394
Cdd:pfam05731 268 SkLPMMAMLRNLCNLLRVgvsaRHHEDLVLQRLQNPKSVIHSRQHPFRFLN 318
 
Name Accession Description Interval E-value
TROVE pfam05731
TROVE domain; This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding ...
197-394 9.28e-07

TROVE domain; This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-binding.


Pssm-ID: 461724  Cd Length: 361  Bit Score: 51.23  E-value: 9.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440216408  197 SDLLLFVQLVKRVQKLLERK-TPFNRTVRKAVLNWYGTKSLDRL-LHFWSIGDGNRWpAHRDLLyRLHfRHANFLPEIIA 274
Cdd:pfam05731 111 TDLFEVAEYCEELAEGDEKKlTGWGRCLRRAMTDWYTSKFAEFLaYQLTKYNTRKHW-SHKDPF-RLP-HPPKFSETSLE 187
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440216408  275 ALRLLSSSPKELSQWPDFLTPL----TSFRETIEGVVKLRLLTDPEQAI--SIVKKLSLSWEHVPFHLLHDPRLAHFLIP 348
Cdd:pfam05731 188 LKGLFRYATKEQRKFEKAYGAVpekkESKRLTLKKLVQRLHISEPAEHVqaLIGKRYRLTWEREPSLRGNSAEVWEELID 267
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 440216408  349 H-MSYEQLLQKWPRLSRL----NSRVRPFAEQLLDKKKLKASNVPPVRLLL 394
Cdd:pfam05731 268 SkLPMMAMLRNLCNLLRVgvsaRHHEDLVLQRLQNPKSVIHSRQHPFRFLN 318
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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