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Conserved domains on  [gi|403321242|gb|AFR38294|]
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cellulose synthase, partial [Populus trichocarpa]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02195 super family cl33434
cellulose synthase A
 1-73 8.48e-56

cellulose synthase A


The actual alignment was detected with superfamily member PLN02195:

Pssm-ID: 215124 [Multi-domain]  Cd Length: 977  Bit Score: 183.63  E-value: 8.48e-56
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242   1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:PLN02195 665 IGWIYGSVTEDILTGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFLSRHCPLWYGYG 737
 
Name Accession Description Interval E-value
PLN02195 PLN02195
cellulose synthase A
 1-73 8.48e-56

cellulose synthase A


Pssm-ID: 215124 [Multi-domain]  Cd Length: 977  Bit Score: 183.63  E-value: 8.48e-56
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242   1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:PLN02195 665 IGWIYGSVTEDILTGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFLSRHCPLWYGYG 737
Cellulose_synt pfam03552
Cellulose synthase; Cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose ...
 1-73 2.28e-55

Cellulose synthase; Cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues, is the major component of wood and thus paper, and is synthesized by plants, most algae, some bacteria and fungi, and even some animals. The genes that synthesize cellulose in higher plants differ greatly from the well-characterized genes found in Acetobacter and Agrobacterium sp. More correctly designated as 'cellulose synthase catalytic subunits', plant cellulose synthase (CesA) proteins are integral membrane proteins, approximately 1,000 amino acids in length. There are a number of highly conserved residues, including several motifs shown to be necessary for processive glycosyltransferase activity.


Pssm-ID: 460970 [Multi-domain]  Cd Length: 715  Bit Score: 180.72  E-value: 2.28e-55
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:pfam03552 413 IGWIYGSVTEDILTGFRMHCRGWRSIYCMPKRDAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPIWYGGR 485
CESA_CelA_like cd06421
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of ...
 1-61 2.09e-12

CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.


Pssm-ID: 133043 [Multi-domain]  Cd Length: 234  Bit Score: 59.12  E-value: 2.09e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 403321242   1 IGWIY-GSVTEDILSGFKMHCRGWRSIYcMPVRPAFkGSAPINLSDRLHQVLRWALGSVEIF 61
Cdd:cd06421  175 IGGFPtDSVTEDLATSLRLHAKGWRSVY-VPEPLAA-GLAPETLAAYIKQRLRWARGMLQIL 234
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 2-69 1.35e-07

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 46.27  E-value: 1.35e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 403321242   2 GWIYGSVTEDILSGFKMHCRGWRSIYCMpvRPAFKGSAPINLSDRLHQVLRWALGSVEIFFsRHCPLW 69
Cdd:COG1215  160 GFDEDTLGEDLDLSLRLLRAGYRIVYVP--DAVVYEEAPETLRALFRQRRRWARGGLQLLL-KHRPLL 224
 
Name Accession Description Interval E-value
PLN02195 PLN02195
cellulose synthase A
 1-73 8.48e-56

cellulose synthase A


Pssm-ID: 215124 [Multi-domain]  Cd Length: 977  Bit Score: 183.63  E-value: 8.48e-56
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242   1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:PLN02195 665 IGWIYGSVTEDILTGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFLSRHCPLWYGYG 737
Cellulose_synt pfam03552
Cellulose synthase; Cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose ...
 1-73 2.28e-55

Cellulose synthase; Cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues, is the major component of wood and thus paper, and is synthesized by plants, most algae, some bacteria and fungi, and even some animals. The genes that synthesize cellulose in higher plants differ greatly from the well-characterized genes found in Acetobacter and Agrobacterium sp. More correctly designated as 'cellulose synthase catalytic subunits', plant cellulose synthase (CesA) proteins are integral membrane proteins, approximately 1,000 amino acids in length. There are a number of highly conserved residues, including several motifs shown to be necessary for processive glycosyltransferase activity.


Pssm-ID: 460970 [Multi-domain]  Cd Length: 715  Bit Score: 180.72  E-value: 2.28e-55
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:pfam03552 413 IGWIYGSVTEDILTGFRMHCRGWRSIYCMPKRDAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPIWYGGR 485
PLN02915 PLN02915
cellulose synthase A [UDP-forming], catalytic subunit
 1-73 1.20e-53

cellulose synthase A [UDP-forming], catalytic subunit


Pssm-ID: 215494 [Multi-domain]  Cd Length: 1044  Bit Score: 177.43  E-value: 1.20e-53
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:PLN02915  733 IGWIYGSVTEDILTGFKMHCRGWKSVYCMPKRPAFKGSAPINLSDRLHQVLRWALGSVEIFMSRHCPLWYAYG 805
PLN02436 PLN02436
cellulose synthase A
 1-73 2.81e-52

cellulose synthase A


Pssm-ID: 215239 [Multi-domain]  Cd Length: 1094  Bit Score: 173.52  E-value: 2.81e-52
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:PLN02436  785 IGWIYGSVTEDILTGFKMHCHGWRSVYCIPKRPAFKGSAPINLSDRLHQVLRWALGSVEIFLSRHCPIWYGYG 857
PLN02638 PLN02638
cellulose synthase A (UDP-forming), catalytic subunit
 1-73 5.98e-52

cellulose synthase A (UDP-forming), catalytic subunit


Pssm-ID: 215343 [Multi-domain]  Cd Length: 1079  Bit Score: 172.80  E-value: 5.98e-52
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGYG 73
Cdd:PLN02638  769 IGWIYGSVTEDILTGFKMHARGWRSIYCMPKRPAFKGSAPINLSDRLNQVLRWALGSVEILFSRHCPIWYGYG 841
PLN02189 PLN02189
cellulose synthase
 1-72 5.20e-51

cellulose synthase


Pssm-ID: 215121 [Multi-domain]  Cd Length: 1040  Bit Score: 170.19  E-value: 5.20e-51
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGY 72
Cdd:PLN02189  730 LGWIYGSITEDILTGFKMHCRGWRSIYCMPKRAAFKGSAPINLSDRLNQVLRWALGSVEIFFSRHSPLLYGY 801
PLN02400 PLN02400
cellulose synthase
 1-72 1.53e-49

cellulose synthase


Pssm-ID: 215224 [Multi-domain]  Cd Length: 1085  Bit Score: 165.92  E-value: 1.53e-49
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYGY 72
Cdd:PLN02400  774 IGWIYGSVTEDILTGFKMHARGWISIYCMPPRPAFKGSAPINLSDRLNQVLRWALGSIEILLSRHCPIWYGY 845
PLN02248 PLN02248
cellulose synthase-like protein
 1-64 1.08e-42

cellulose synthase-like protein


Pssm-ID: 215138 [Multi-domain]  Cd Length: 1135  Bit Score: 146.33  E-value: 1.08e-42
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 403321242    1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSR 64
Cdd:PLN02248  828 VGWIYGSVTEDVVTGYRMHNRGWRSVYCVTKRDAFRGTAPINLTDRLHQVLRWATGSVEIFFSR 891
PLN02893 PLN02893
Cellulose synthase-like protein
 1-71 2.48e-27

Cellulose synthase-like protein


Pssm-ID: 215483 [Multi-domain]  Cd Length: 734  Bit Score: 102.48  E-value: 2.48e-27
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 403321242   1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLWYG 71
Cdd:PLN02893 438 MGFRYGSLVEDYYTGYRLQCEGWKSIFCNPKRPAFLGDSPINLHDVLNQQKRWSVGLLEVAFSKYSPITFG 508
PLN02190 PLN02190
cellulose synthase-like protein
 1-68 1.63e-15

cellulose synthase-like protein


Pssm-ID: 215122 [Multi-domain]  Cd Length: 756  Bit Score: 68.74  E-value: 1.63e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 403321242   1 IGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPL 68
Cdd:PLN02190 451 IGWLYDSVAEDLNTSIGIHSRGWTSSYISPDPPAFLGSMPPGGPEAMVQQRRWATGLIEVLFNKQSPL 518
CESA_CelA_like cd06421
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of ...
 1-61 2.09e-12

CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.


Pssm-ID: 133043 [Multi-domain]  Cd Length: 234  Bit Score: 59.12  E-value: 2.09e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 403321242   1 IGWIY-GSVTEDILSGFKMHCRGWRSIYcMPVRPAFkGSAPINLSDRLHQVLRWALGSVEIF 61
Cdd:cd06421  175 IGGFPtDSVTEDLATSLRLHAKGWRSVY-VPEPLAA-GLAPETLAAYIKQRLRWARGMLQIL 234
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 2-69 1.35e-07

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 46.27  E-value: 1.35e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 403321242   2 GWIYGSVTEDILSGFKMHCRGWRSIYCMpvRPAFKGSAPINLSDRLHQVLRWALGSVEIFFsRHCPLW 69
Cdd:COG1215  160 GFDEDTLGEDLDLSLRLLRAGYRIVYVP--DAVVYEEAPETLRALFRQRRRWARGGLQLLL-KHRPLL 224
bcsA PRK11498
cellulose synthase catalytic subunit; Provisional
 7-61 6.64e-06

cellulose synthase catalytic subunit; Provisional


Pssm-ID: 236918 [Multi-domain]  Cd Length: 852  Bit Score: 41.55  E-value: 6.64e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 403321242   7 SVTEDILSGFKMHCRGWRSIYcmpVR-PAFKGSAPINLSDRLHQVLRWALGSVEIF 61
Cdd:PRK11498 440 TVTEDAHTSLRLHRRGYTSAY---MRiPQAAGLATESLSAHIGQRIRWARGMVQIF 492
Glyco_trans_2_3 pfam13632
Glycosyl transferase family group 2; Members of this family of prokaryotic proteins include ...
 2-69 5.20e-03

Glycosyl transferase family group 2; Members of this family of prokaryotic proteins include putative glucosyltransferases, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433365 [Multi-domain]  Cd Length: 192  Bit Score: 33.08  E-value: 5.20e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 403321242    2 GWIYGSVTEDILSGFKMHCRGWRSIYCmpVRPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPLW 69
Cdd:pfam13632  89 GWDDGSVSEDFDFGLRLQRAGYRVRFA--PYSAVYEKSPLTFRDFLRQRRRWAYGCLLILLIRLLGYL 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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