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Conserved domains on  [gi|384946988|gb|AFI37099|]
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kinectin isoform a [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
679-1348 2.40e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 2.40e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   679 DDKIRLLEEQLQH--EISNKMEEFKILNDQNKALKLEVQ--KLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Cdd:TIGR02168  192 EDILNELERQLKSleRQAEKAERYKELKAELRELELALLvlRLEELREElEELQEELKEAEEELEELTAELQELEEKLEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   754 GLIQVATKEEELNAIRTENSSLTKEVQDLKA-KQNDQVSFASLVEELKkvihEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQqKQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEEKLE 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   833 DLKQEIKALKEEIGNVQLEKAQQLS----ITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL- 907
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESrleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELl 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   908 --------KAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDL---SSKTKLLQDVQDENKLFKSQ 976
Cdd:TIGR02168  428 kkleeaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlQARLDSLERLQENLEGFSEG 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   977 IEQLKQQNYQQASSFPPHEELLKVISEREKEISG---------LWNELDSLKDAVEHQRKKNN-----------DLREKN 1036
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAAIEAalggrlqavVVENLNAAKKAIAFLKQNELgrvtflpldsiKGTEIQ 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1037 WEAMEALASTEKMLQ--DKVNKTSKERQ-------QQVEAVE--LEAKEVLKKLFPKVSVPSnlsysewLHGFEKKAKEC 1105
Cdd:TIGR02168  588 GNDREILKNIEGFLGvaKDLVKFDPKLRkalsyllGGVLVVDdlDNALELAKKLRPGYRIVT-------LDGDLVRPGGV 660
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1106 MAGTSGSEEVKVLEHK--LKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFT 1183
Cdd:TIGR02168  661 ITGGSAKTNSSILERRreIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1184 SSEQELERLRRENKDIENLRREREHLEMELEKAEmerstyvTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLN 1263
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAE-------EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1264 ETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVN 1343
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                   ....*
gi 384946988  1344 QQLTK 1348
Cdd:TIGR02168  894 SELEE 898
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
398-951 6.47e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 6.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKK 477
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  478 NAEQAvtqlKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Cdd:COG1196   313 ELEER----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEEL 637
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  638 KDIQNmnfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQheISNKMEEFKILNDQNKALKLEVQKL 717
Cdd:COG1196   469 LEEAA---LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAA 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  718 QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMN 877
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 384946988  878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEI-VLKEKENELKRVEAMLKE 951
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELERELERLEREIEA 778
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
29-160 6.80e-12

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


:

Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 64.37  E-value: 6.80e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988    29 MKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKK------EIQNGNLHESD----SESVPRDFKLSDALAVEDdqVV 98
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTPTEKEKKKKEKKKEKKKkskkkeEKPNGKLPESEqadeSEEEPREFKTPDEAPSAA--LE 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988    99 PVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAA 160
Cdd:pfam05104   79 PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEEPPA 140
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
679-1348 2.40e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 2.40e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   679 DDKIRLLEEQLQH--EISNKMEEFKILNDQNKALKLEVQ--KLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Cdd:TIGR02168  192 EDILNELERQLKSleRQAEKAERYKELKAELRELELALLvlRLEELREElEELQEELKEAEEELEELTAELQELEEKLEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   754 GLIQVATKEEELNAIRTENSSLTKEVQDLKA-KQNDQVSFASLVEELKkvihEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQqKQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEEKLE 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   833 DLKQEIKALKEEIGNVQLEKAQQLS----ITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL- 907
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESrleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELl 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   908 --------KAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDL---SSKTKLLQDVQDENKLFKSQ 976
Cdd:TIGR02168  428 kkleeaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlQARLDSLERLQENLEGFSEG 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   977 IEQLKQQNYQQASSFPPHEELLKVISEREKEISG---------LWNELDSLKDAVEHQRKKNN-----------DLREKN 1036
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAAIEAalggrlqavVVENLNAAKKAIAFLKQNELgrvtflpldsiKGTEIQ 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1037 WEAMEALASTEKMLQ--DKVNKTSKERQ-------QQVEAVE--LEAKEVLKKLFPKVSVPSnlsysewLHGFEKKAKEC 1105
Cdd:TIGR02168  588 GNDREILKNIEGFLGvaKDLVKFDPKLRkalsyllGGVLVVDdlDNALELAKKLRPGYRIVT-------LDGDLVRPGGV 660
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1106 MAGTSGSEEVKVLEHK--LKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFT 1183
Cdd:TIGR02168  661 ITGGSAKTNSSILERRreIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1184 SSEQELERLRRENKDIENLRREREHLEMELEKAEmerstyvTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLN 1263
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAE-------EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1264 ETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVN 1343
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                   ....*
gi 384946988  1344 QQLTK 1348
Cdd:TIGR02168  894 SELEE 898
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-1081 3.79e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 3.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  446 AELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEEL 605
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  606 HKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLL 685
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  686 EEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEkLKTVEELLETgLIQVATKEEEL 765
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV-LIGVEAAYEA-ALEAALAAALQ 549
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEelkkvihEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Cdd:COG1196   550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK-------IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  846 GNVQLEKAQQLSITSQVQELQNLLKGKEEQmntMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSA 925
Cdd:COG1196   623 LGRTLVAARLEAALRRAVTLAGRLREVTLE---GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  926 SQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKlfksqiEQLKQQNYQQASSFPPHEELLKVISERE 1005
Cdd:COG1196   700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE------ELLEEEALEELPEPPDLEELERELERLE 773
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1006 KEISGLWN-------ELDSLKDAVEHQRKKNNDLReknweamEALASTEKMLqDKVNKTSKER-QQQVEAVELEAKEVLK 1077
Cdd:COG1196   774 REIEALGPvnllaieEYEELEERYDFLSEQREDLE-------EARETLEEAI-EEIDRETRERfLETFDAVNENFQELFP 845

                  ....
gi 384946988 1078 KLFP 1081
Cdd:COG1196   846 RLFG 849
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
398-951 6.47e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 6.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKK 477
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  478 NAEQAvtqlKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Cdd:COG1196   313 ELEER----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEEL 637
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  638 KDIQNmnfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQheISNKMEEFKILNDQNKALKLEVQKL 717
Cdd:COG1196   469 LEEAA---LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAA 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  718 QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMN 877
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 384946988  878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEI-VLKEKENELKRVEAMLKE 951
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELERELERLEREIEA 778
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
29-160 6.80e-12

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 64.37  E-value: 6.80e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988    29 MKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKK------EIQNGNLHESD----SESVPRDFKLSDALAVEDdqVV 98
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTPTEKEKKKKEKKKEKKKkskkkeEKPNGKLPESEqadeSEEEPREFKTPDEAPSAA--LE 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988    99 PVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAA 160
Cdd:pfam05104   79 PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEEPPA 140
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
442-907 4.70e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 4.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   442 SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTaEHEAAQQDLQSK 521
Cdd:TIGR04523  148 KKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK-SLESQISELKKQ 226
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA--QTSAS 599
Cdd:TIGR04523  227 NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDlnNQKEQ 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   600 VLAEELHKVIAEKDKQIKQTEDSLANE-------RDHLTSKEEELKDIQNMNFLLKAE-------VQKLQALANEQAAAA 665
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNnkiisqlNEQISQLKKELTNSESENSEKQREleekqneIEKLKKENQSYKQEI 386
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   666 HELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVV------------EQM 733
Cdd:TIGR04523  387 KNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVkeliiknldntrESL 466
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNdqvSFASLVEELKKVIHEKDGKIKSV 813
Cdd:TIGR04523  467 ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS---SLKEKIEKLESEKKEKESKISDL 543
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   814 EE--LLEAELLKVANKEKTVQDLKQEIKALKEEignvqlekaqQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Cdd:TIGR04523  544 EDelNKDDFELKKENLEKEIDEKNKEIEELKQT----------QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613
                          490
                   ....*....|....*.
gi 384946988   892 NTGKWLQDLQEENESL 907
Cdd:TIGR04523  614 SLEKELEKAKKENEKL 629
PTZ00121 PTZ00121
MAEBL; Provisional
452-1077 4.05e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 4.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  452 RQDYARLVNELTEKTGKLQQEEVQKknAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS 531
Cdd:PTZ00121 1165 KAEEARKAEDAKKAEAARKAEEVRK--AEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEA 1242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  532 LHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESlqMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEElhkviAE 611
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE-----AK 1315
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  612 KDKQIKQTEDSLANERDHLTSKEEELKDIQNMNfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA-KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  692 EISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEK---DEKLKTVEElletgliqvATKEEELNAI 768
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkaDEAKKKAEE---------AKKAEEAKKK 1465
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  769 RTEnsslTKEVQDLKAKQNDqvsfASLVEELKKVIHEkdGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEignv 848
Cdd:PTZ00121 1466 AEE----AKKADEAKKKAEE----AKKADEAKKKAEE--AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE---- 1531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  849 QLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE----VSS 924
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEkkmkAEE 1611
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  925 ASQFEELEIVLKE--KENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVIS 1002
Cdd:PTZ00121 1612 AKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 384946988 1003 EREKEISGLWNELDSLKDAVEHQRKKNNDLR---EKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLK 1077
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKkaeEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
376-983 4.47e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 4.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   376 MKDRIGTLEKEHnvfQNKIHVSYQetqQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKlRQDY 455
Cdd:pfam15921  243 VEDQLEALKSES---QNKIELLLQ---QHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ-NSMY 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   456 ARLVNELtektgklqqeevqkknaEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Cdd:pfam15921  316 MRQLSDL-----------------ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQ 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   536 LTDTLVSKQQLEQRLMQLMESEQKRVNKE--------------ESLQMQVQDILEQNEALKAQIQ-QFHSQIAAQTSASV 600
Cdd:pfam15921  379 LQKLLADLHKREKELSLEKEQNKRLWDRDtgnsitidhlrrelDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNE 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   601 LAEELHKVIAekdkQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEvqkLQALANEQAAAAHELEKMQQSVYVKdd 680
Cdd:pfam15921  459 SLEKVSSLTA----QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS---LQEKERAIEATNAEITKLRSRVDLK-- 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   681 kirllEEQLQHeISNKMEEFKILNDQNKALKLEvqklqtlvseqpnkdvveqmekcIQEKDEKLKTVEELLETGLIQVAT 760
Cdd:pfam15921  530 -----LQELQH-LKNEGDHLRNVQTECEALKLQ-----------------------MAEKDKVIEILRQQIENMTQLVGQ 580
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   761 KEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKA 840
Cdd:pfam15921  581 HGRTAGAMQVEKAQLEKEINDRRLELQE---FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQ 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   841 LKEEIGNVQLEKAqqlSITSQVQELQNLLKGKEEQM----NTMKAVLEEKEKDLANTGKWLQDLqeenESLKAHVQEVAQ 916
Cdd:pfam15921  658 LLNEVKTSRNELN---SLSEDYEVLKRNFRNKSEEMetttNKLKMQLKSAQSELEQTRNTLKSM----EGSDGHAMKVAM 730
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 384946988   917 HNLKEVSSA-SQFEELEI---VLKEKENELKRVEAMLKERESDLSSKtklLQDVQDENKLFKSQIEQLKQQ 983
Cdd:pfam15921  731 GMQKQITAKrGQIDALQSkiqFLEEAMTNANKEKHFLKEEKNKLSQE---LSTVATEKNKMAGELEVLRSQ 798
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
349-781 7.14e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 50.82  E-value: 7.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  349 AATKDRCKQLTQEMmsEKERSNVVIARmKDRIGTLEKEHNVFQNKihvsyQETQQMQMKFQQVREQMEAEIAHLKQENGI 428
Cdd:PRK10929   19 AATAPDEKQITQEL--EQAKAAKTPAQ-AEIVEALQSALNWLEER-----KGSLERAKQYQQVIDNFPKLSAELRQQLNN 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  429 LRDAVSNttnqLESKQSAelNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRT 508
Cdd:PRK10929   91 ERDEPRS----VPPNMST--DALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLQTLG 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  509 AEHEAAQqdlQSKFVAKENEVQSLHSKLtdtlvskQQLEqrLMQLMESeqkrvNKEESLQMQVQDILEQNEALKAQIQQF 588
Cdd:PRK10929  165 TPNTPLA---QAQLTALQAESAALKALV-------DELE--LAQLSAN-----NRQELARLRSELAKKRSQQLDAYLQAL 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  589 HSQIAAQ---------TSASVLAE---ELHKVIAEKDKQIKQTEDSL---ANERDHLTSKE-----EELKDIQNMNFL-- 646
Cdd:PRK10929  228 RNQLNSQrqreaeralESTELLAEqsgDLPKSIVAQFKINRELSQALnqqAQRMDLIASQQrqaasQTLQVRQALNTLre 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  647 --------------LKAEVQKLQalaneqaaaahELEKMQQsvyVKDDKIRLLEEQLQHEisnkmeefKILNDQNKALKL 712
Cdd:PRK10929  308 qsqwlgvsnalgeaLRAQVARLP-----------EMPKPQQ---LDTEMAQLRVQRLRYE--------DLLNKQPQLRQI 365
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  713 EVQKLQTLVSEQpnkdvveqmeKCIQekDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLT---KEVQD 781
Cdd:PRK10929  366 RQADGQPLTAEQ----------NRIL--DAQLRTQRELLNSLLSGGDTLILELTKLKVANSQLEdalKEVNE 425
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
296-588 8.38e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 8.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   296 FSEDEALCVVDLLKEKSGVIQDALKKSSKgELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIAR 375
Cdd:pfam12128  597 ASEEELRERLDKAEEALQSAREKQAAAEE-QLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE 675
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   376 MKD----RIGTLEKEHNVFQNKIHVSYQETQ--------QMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESK 443
Cdd:pfam12128  676 RKDsaneRLNSLEAQLKQLDKKHQAWLEEQKeqkreartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW 755
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   444 QSAELNKLRQD---YARLVNELTEKTGKLQQEEVQkknaEQAVTQLKVQLQEaerRWEEVQSYIRKRTAEHEAAQQDLQS 520
Cdd:pfam12128  756 YKRDLASLGVDpdvIAKLKREIRTLERKIERIAVR----RQEVLRYFDWYQE---TWLQRRPRLATQLSNIERAISELQQ 828
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL---MESEQKRVNK------EESLQM-------QVQDILEQNEALKAQ 584
Cdd:pfam12128  829 QLARLIADTKLRRAKLEMERKASEKQQVRLSENlrgLRCEMSKLATlkedanSEQAQGsigerlaQLEDLKLKRDYLSES 908

                   ....
gi 384946988   585 IQQF 588
Cdd:pfam12128  909 VKKY 912
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
412-621 5.69e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 5.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  412 REQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY-------ARLVN-ELTEKTGKLQQEEVQKKNAEQAV 483
Cdd:NF012221 1564 KERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQrdaileeSRAVTkELTTLAQGLDALDSQATYAGESG 1643
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  484 TQLKVQLqeAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKlTDTLVskQQLEQRLMQLMESEQKRVNK 563
Cdd:NF012221 1644 DQWRNPF--AGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAK-SEAGV--AQGEQNQANAEQDIDDAKAD 1718
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  564 EESLQMQVqdILEQNEALKAQIQQFHS----QIAAQTSASVLAEELHKVIAEKdKQIKQTED 621
Cdd:NF012221 1719 AEKRKDDA--LAKQNEAQQAESDANAAandaQSRGEQDASAAENKANQAQADA-KGAKQDES 1777
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
679-1348 2.40e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 2.40e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   679 DDKIRLLEEQLQH--EISNKMEEFKILNDQNKALKLEVQ--KLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Cdd:TIGR02168  192 EDILNELERQLKSleRQAEKAERYKELKAELRELELALLvlRLEELREElEELQEELKEAEEELEELTAELQELEEKLEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   754 GLIQVATKEEELNAIRTENSSLTKEVQDLKA-KQNDQVSFASLVEELKkvihEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQqKQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEEKLE 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   833 DLKQEIKALKEEIGNVQLEKAQQLS----ITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL- 907
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESrleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELl 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   908 --------KAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDL---SSKTKLLQDVQDENKLFKSQ 976
Cdd:TIGR02168  428 kkleeaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlQARLDSLERLQENLEGFSEG 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   977 IEQLKQQNYQQASSFPPHEELLKVISEREKEISG---------LWNELDSLKDAVEHQRKKNN-----------DLREKN 1036
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAAIEAalggrlqavVVENLNAAKKAIAFLKQNELgrvtflpldsiKGTEIQ 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1037 WEAMEALASTEKMLQ--DKVNKTSKERQ-------QQVEAVE--LEAKEVLKKLFPKVSVPSnlsysewLHGFEKKAKEC 1105
Cdd:TIGR02168  588 GNDREILKNIEGFLGvaKDLVKFDPKLRkalsyllGGVLVVDdlDNALELAKKLRPGYRIVT-------LDGDLVRPGGV 660
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1106 MAGTSGSEEVKVLEHK--LKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFT 1183
Cdd:TIGR02168  661 ITGGSAKTNSSILERRreIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1184 SSEQELERLRRENKDIENLRREREHLEMELEKAEmerstyvTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLN 1263
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAE-------EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1264 ETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVN 1343
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                   ....*
gi 384946988  1344 QQLTK 1348
Cdd:TIGR02168  894 SELEE 898
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
468-1270 2.52e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 2.52e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   468 KLQQEEVQKK--NAEQAVTQLKVQLQEAERRW-------EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTD 538
Cdd:TIGR02168  171 KERRKETERKleRTRENLDRLEDILNELERQLkslerqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   539 tLVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQFHSQIAAQtsaSVLAEELHKVIAEKDKQIK 617
Cdd:TIGR02168  251 -AEEELEELTAELQELEEKLEELRLEvSELEEEIEELQKELYALANEISRLEQQKQIL---RERLANLERQLEELEAQLE 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   618 QTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM 697
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   698 EEFKILNDQNKALKLEVQKLQTLVSEQPNKDV---VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE------------KTVQDLKQEIKALK 842
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEaalggrlqavvvENLNAAKKAIAFLK 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   843 E-EIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWL------QDLQEENESLKAHVQEVA 915
Cdd:TIGR02168  567 QnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRPGYR 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   916 QHNL------KEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS 989
Cdd:TIGR02168  647 IVTLdgdlvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   990 SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQ---QVE 1066
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALD 806
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1067 AVELEAKEVLKKLFPKVSVPSNLSysewlhgFEKKAKECMAGTSgSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAEt 1146
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLE-------RRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESELEA- 877
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1147 egiLQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIEN------------LRREREHLEMELE 1214
Cdd:TIGR02168  878 ---LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELrleglevridnlQERLSEEYSLTLE 954
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 384946988  1215 KAEMERSTYVTEVRELKDLLTELQKKLD-------DSYSEAVRQNEELNLLKAQ---LNETLTKLR 1270
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLENKIKelgpvnlAAIEEYEELKERYDFLTAQkedLTEAKETLE 1020
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
453-1297 7.10e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 7.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   453 QDYARLVNELTEKTGKLQQEEVQKKNAEQAvtQLKVQLQEAERRWEEVQSYIRKRTAEHEaaqqDLQSKFVAKENEVQSL 532
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELE--ELQEELKEAEEELEELTAELQELEEKLE----ELRLEVSELEEEIEEL 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   533 HSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIaaqtsasvlaEELHKVIAEK 612
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL----------EELKEELESL 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   613 DKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQsvyvkddkiRLLEEQLQHE 692
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE---------RLQQEIEELL 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   693 ISNKMEEFKILNDQNKALKLEVQKLQTlvseqpNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN 772
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQE------ELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   773 SSLTKEVQDLKAKQNDQVSFASLVEELKKViHEKDGKIKSVEELLEAELLKVANKEktvqDLKQEIKALKE-EIGNVQLE 851
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVVVENLN----AAKKAIAFLKQnELGRVTFL 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   852 KAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWL------QDLQEENESLKAHVQEVAQHNL------ 919
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRPGYRIVTLdgdlvr 656
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   920 KEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK 999
Cdd:TIGR02168  657 PGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA 736
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1000 VISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVlkkl 1079
Cdd:TIGR02168  737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---- 812
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1080 fpkvsvpsnlsysewlhgfekkakecmagtsgsEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQ 1159
Cdd:TIGR02168  813 ---------------------------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1160 EENKWKVKVDESHKTIKQMQSSFTSSEQELERLRrenKDIENLRREREHLEmelekaemerstyvTEVRELKDLLTELQK 1239
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLR---SELEELSEELRELE--------------SKRSELRRELEELRE 922
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 384946988  1240 KLDDSyseavrqNEELNLLKAQLNETLTKLRTEQN--------ERQKVAGDLHKAQQSLELIQSKI 1297
Cdd:TIGR02168  923 KLAQL-------ELRLEGLEVRIDNLQERLSEEYSltleeaeaLENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-1081 3.79e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 3.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  446 AELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEEL 605
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  606 HKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLL 685
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  686 EEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEkLKTVEELLETgLIQVATKEEEL 765
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV-LIGVEAAYEA-ALEAALAAALQ 549
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEelkkvihEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Cdd:COG1196   550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK-------IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  846 GNVQLEKAQQLSITSQVQELQNLLKGKEEQmntMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSA 925
Cdd:COG1196   623 LGRTLVAARLEAALRRAVTLAGRLREVTLE---GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  926 SQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKlfksqiEQLKQQNYQQASSFPPHEELLKVISERE 1005
Cdd:COG1196   700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE------ELLEEEALEELPEPPDLEELERELERLE 773
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1006 KEISGLWN-------ELDSLKDAVEHQRKKNNDLReknweamEALASTEKMLqDKVNKTSKER-QQQVEAVELEAKEVLK 1077
Cdd:COG1196   774 REIEALGPvnllaieEYEELEERYDFLSEQREDLE-------EARETLEEAI-EEIDRETRERfLETFDAVNENFQELFP 845

                  ....
gi 384946988 1078 KLFP 1081
Cdd:COG1196   846 RLFG 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
458-1199 6.05e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 6.05e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   458 LVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQ---QDLQSKFVAKENEVQSLHS 534
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelYALANEISRLEQQKQILRE 309
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   535 KLTDtlvSKQQLEQRLMQLMESEQKRVNKEESLQM---QVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE 611
Cdd:TIGR02168  310 RLAN---LERQLEELEAQLEELESKLDELAEELAEleeKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   612 KDKQIKQTEDSLANErdhLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAH-----ELEKMQQSVYVKDDKIRLLE 686
Cdd:TIGR02168  387 KVAQLELQIASLNNE---IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqaeleELEEELEELQEELERLEEAL 463
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   687 EQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVS--EQPNKDVVEQMEKCIQEKDE-----KLKTVEELLETGLiqVA 759
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQEnlEGFSEGVKALLKNQSGLSGIlgvlsELISVDEGYEAAI--EA 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   760 TKEEELNAIRTENSSLTKE-VQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKT-------- 830
Cdd:TIGR02168  542 ALGGRLQAVVVENLNAAKKaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyl 621
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   831 ------VQDLKQEIKALKE--------------------------EIGNVQLEKAQQLS-ITSQVQELQNLLKGKEEQMN 877
Cdd:TIGR02168  622 lggvlvVDDLDNALELAKKlrpgyrivtldgdlvrpggvitggsaKTNSSILERRREIEeLEEKIEELEEKIAELEKALA 701
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   878 TMKAVLEEKEKDLANTGKWLQDLQ----EENESLKAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERE 953
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEELSrqisALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   954 SDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLR 1033
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1034 EKNWEAMEAlastekmLQDKVNKTSKERQQQVEAVElEAKEVLKKLfpkvsvpsnlsysewlhgfekkakecmagtsgSE 1113
Cdd:TIGR02168  862 EELEELIEE-------LESELEALLNERASLEEALA-LLRSELEEL--------------------------------SE 901
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1114 EVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQrsvEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLR 1193
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ---ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978

                   ....*.
gi 384946988  1194 RENKDI 1199
Cdd:TIGR02168  979 NKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
398-951 6.47e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 6.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKK 477
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  478 NAEQAvtqlKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Cdd:COG1196   313 ELEER----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEEL 637
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  638 KDIQNmnfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQheISNKMEEFKILNDQNKALKLEVQKL 717
Cdd:COG1196   469 LEEAA---LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAA 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  718 QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMN 877
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 384946988  878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEI-VLKEKENELKRVEAMLKE 951
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
309-1083 1.08e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.08e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   309 KEKSGVIQDALKKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKER---SNVVIARMKDRIGTLEK 385
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEleeLEAELEELESRLEELEE 379
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   386 EHNVFQNKIHVSYQETQQMQMKFQqvreQMEAEIAHLKQENGILRdavSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIE----RLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEEL 452
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   466 TGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSyirkRTAEHEAAQQDLQSKFVAKENEVQSLhSKLTDTLvskqq 545
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQA----RLDSLERLQENLEGFSEGVKALLKNQ-SGLSGIL----- 522
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   546 leQRLMQLMESEQK-RVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA-SVLAEELHKVIAEKDKQIKQTEDSL 623
Cdd:TIGR02168  523 --GVLSELISVDEGyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTfLPLDSIKGTEIQGNDREILKNIEGF 600
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   624 ANERDHLTSKEEELKDiqNMNFLL-----------KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRK--ALSYLLggvlvvddldnALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRRE 678
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   693 ISNKMEEFKILNDQNKALKLEVQKLQTLVSEQpnKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN 772
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEEL--EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   773 SSLTKEVQDLKAKqndqvsfaslVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK 852
Cdd:TIGR02168  757 TELEAEIEELEER----------LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   853 AQQL----SITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLAntgkwlqdlqEENESLKAHVQEVAQHNLKEVSSASQF 928
Cdd:TIGR02168  827 ESLErriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIE----------ELESELEALLNERASLEEALALLRSEL 896
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   929 EELEIVLKEKENELKRVEAMLKEResdlssKTKLLQDVQDENKLfKSQIEQLKQQNYQQASSfpPHEELLKVISEREKEI 1008
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEEL------REKLAQLELRLEGL-EVRIDNLQERLSEEYSL--TLEEAEALENKIEDDE 967
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1009 SGLWNELDSLKdavehqrKKNNDLREKNWEAMEALASTEKMLQ------DKVNKTSKERQQQVEAVELEAKEVLKKLFPK 1082
Cdd:TIGR02168  968 EEARRRLKRLE-------NKIKELGPVNLAAIEEYEELKERYDfltaqkEDLTEAKETLEEAIEEIDREARERFKDTFDQ 1040

                   .
gi 384946988  1083 V 1083
Cdd:TIGR02168 1041 V 1041
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
29-160 6.80e-12

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 64.37  E-value: 6.80e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988    29 MKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKK------EIQNGNLHESD----SESVPRDFKLSDALAVEDdqVV 98
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTPTEKEKKKKEKKKEKKKkskkkeEKPNGKLPESEqadeSEEEPREFKTPDEAPSAA--LE 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988    99 PVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAA 160
Cdd:pfam05104   79 PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEEPPA 140
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
442-907 4.70e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 4.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   442 SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTaEHEAAQQDLQSK 521
Cdd:TIGR04523  148 KKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK-SLESQISELKKQ 226
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA--QTSAS 599
Cdd:TIGR04523  227 NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDlnNQKEQ 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   600 VLAEELHKVIAEKDKQIKQTEDSLANE-------RDHLTSKEEELKDIQNMNFLLKAE-------VQKLQALANEQAAAA 665
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNnkiisqlNEQISQLKKELTNSESENSEKQREleekqneIEKLKKENQSYKQEI 386
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   666 HELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVV------------EQM 733
Cdd:TIGR04523  387 KNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVkeliiknldntrESL 466
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   734 EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNdqvSFASLVEELKKVIHEKDGKIKSV 813
Cdd:TIGR04523  467 ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS---SLKEKIEKLESEKKEKESKISDL 543
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   814 EE--LLEAELLKVANKEKTVQDLKQEIKALKEEignvqlekaqQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Cdd:TIGR04523  544 EDelNKDDFELKKENLEKEIDEKNKEIEELKQT----------QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613
                          490
                   ....*....|....*.
gi 384946988   892 NTGKWLQDLQEENESL 907
Cdd:TIGR04523  614 SLEKELEKAKKENEKL 629
PTZ00121 PTZ00121
MAEBL; Provisional
452-1077 4.05e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 4.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  452 RQDYARLVNELTEKTGKLQQEEVQKknAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS 531
Cdd:PTZ00121 1165 KAEEARKAEDAKKAEAARKAEEVRK--AEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEA 1242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  532 LHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESlqMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEElhkviAE 611
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE-----AK 1315
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  612 KDKQIKQTEDSLANERDHLTSKEEELKDIQNMNfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA-KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  692 EISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEK---DEKLKTVEElletgliqvATKEEELNAI 768
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkaDEAKKKAEE---------AKKAEEAKKK 1465
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  769 RTEnsslTKEVQDLKAKQNDqvsfASLVEELKKVIHEkdGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEignv 848
Cdd:PTZ00121 1466 AEE----AKKADEAKKKAEE----AKKADEAKKKAEE--AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE---- 1531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  849 QLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE----VSS 924
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEkkmkAEE 1611
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  925 ASQFEELEIVLKE--KENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVIS 1002
Cdd:PTZ00121 1612 AKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 384946988 1003 EREKEISGLWNELDSLKDAVEHQRKKNNDLR---EKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLK 1077
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKkaeEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
309-1084 2.02e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 2.02e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   309 KEKSGVIQDALKKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLT---QEMMSEKERSNVVIARMKDRIGTL-E 384
Cdd:TIGR02169  207 REKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTeeiSELEKRLEEIEQLLEELNKKIKDLgE 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   385 KEHNVFQNKI---HVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNE 461
Cdd:TIGR02169  287 EEQLRVKEKIgelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER-KRRDKLTEEYAELKEE 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   462 LTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRK---RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTD 538
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKED 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   539 TLVSKQQLEQRLMQL---MESEQKRVNKEESLQMQVQDILEQNE----ALKAQIQQFHSQIAAQTSASVLAEE----LHK 607
Cdd:TIGR02169  446 KALEIKKQEWKLEQLaadLSKYEQELYDLKEEYDRVEKELSKLQrelaEAEAQARASEERVRGGRAVEEVLKAsiqgVHG 525
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   608 VIAE----KDKQIKQTEDSLANERDHLTSKEEE--------LKD--IQNMNFLLKAEVQKLQAlaneqaaaahELEKMQQ 673
Cdd:TIGR02169  526 TVAQlgsvGERYATAIEVAAGNRLNNVVVEDDAvakeaielLKRrkAGRATFLPLNKMRDERR----------DLSILSE 595
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   674 SVYVkDDKIRLLEEQLQHE-----------ISNKMEEFKILNDQNKALKLEVQKLQT-------LVSEQPNKDVVEQMEK 735
Cdd:TIGR02169  596 DGVI-GFAVDLVEFDPKYEpafkyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKsgamtggSRAPRGGILFSRSEPA 674
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   736 CIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQN----DQVSFASLVEELKKVIHEKDGKIK 811
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEqleqEEEKLKERLEELEEDLSSLEQEIE 754
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   812 SVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKaqqlsITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Cdd:TIGR02169  755 NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPE-----IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   892 NTGKWLQDLQEENESLKAHVQEVAQhnlKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENK 971
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEK---EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE 906
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   972 LFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLR---EKNWEAMEALASTEK 1048
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRalePVNMLAIQEYEEVLK 986
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 384946988  1049 M---LQDKVNKTSKER---QQQVEAVELEAKEVLKKLFPKVS 1084
Cdd:TIGR02169  987 RldeLKEKRAKLEEERkaiLERIEEYEKKKREVFMEAFEAIN 1028
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
741-1294 3.09e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 3.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLkakqndqvsfaslvEELKKVIHEKDGKIKSVEELLEAE 820
Cdd:PRK03918  192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL--------------EELKEEIEELEKELESLEGSKRKL 257
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  821 LLKVANKEKTVQDLKQEIKALKEEIGNVqlekaqqlsitsqvqelqNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 900
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKEL------------------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRL 319
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  901 QEENESLKAHVQEVAqhnlkevSSASQFEELEIVLKEKENELKRVEAMLKERESdlsSKTKLLQDVQDENKLFKSQIEQL 980
Cdd:PRK03918  320 EEEINGIEERIKELE-------EKEERLEELKKKLKELEKRLEELEERHELYEE---AKAKKEELERLKKRLTGLTPEKL 389
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  981 KQQnYQQASSfpPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDL----REKNWEAMEALASTEKMLQDKVNK 1056
Cdd:PRK03918  390 EKE-LEELEK--AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcgRELTEEHRKELLEEYTAELKRIEK 466
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1057 TSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECMAG--TSGSEEVKVLEHKLKEADEMHTLLQL 1134
Cdd:PRK03918  467 ELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEelEKKAEEYEKLKEKLIKLKGEIKSLKK 546
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1135 ECEK---YKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEM 1211
Cdd:PRK03918  547 ELEKleeLKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEE 626
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1212 ELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVR---------------QNEELNLLKAQLNETLTKLRTEQNER 1276
Cdd:PRK03918  627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELReeylelsrelaglraELEELEKRREEIKKTLEKLKEELEER 706
                         570
                  ....*....|....*...
gi 384946988 1277 QKVAGDLHKAQQSLELIQ 1294
Cdd:PRK03918  707 EKAKKELEKLEKALERVE 724
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
534-1075 8.42e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 8.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  534 SKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKD 613
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  614 KQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKaEVQKLQALANEQAAAAHELEKMQQSVyvkDDKIRLLEEQLQhEI 693
Cdd:PRK03918  259 EKIRELEERIEELKKEIEELEEKVKELKELKEKAE-EYIKLSEFYEEYLDELREIEKRLSRL---EEEINGIEERIK-EL 333
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  694 SNKMEEFKILNDQNKALKLEVQKLQTLVSE-QPNKDVVEQMEKCIQE-KDEKLKTVEELLETGLIQVATKEEELNAIRTE 771
Cdd:PRK03918  334 EEKEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELERLKKRlTGLTPEKLEKELEELEKAKEEIEEEISKITAR 413
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  772 NSSLTKEVQDLK--------AKQNDQVSFASLVEELKKVIHEK--------------DGKIKSVEELLEAELLKVANKEK 829
Cdd:PRK03918  414 IGELKKEIKELKkaieelkkAKGKCPVCGRELTEEHRKELLEEytaelkriekelkeIEEKERKLRKELRELEKVLKKES 493
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  830 TVQDLKQ---EIKALKEEIGNVQLEKAQQLS-ITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENE 905
Cdd:PRK03918  494 ELIKLKElaeQLKELEEKLKKYNLEELEKKAeEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELA 573
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  906 SLKAHVQEVAQHNLKEVSsaSQFEELE------IVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQ 979
Cdd:PRK03918  574 ELLKELEELGFESVEELE--ERLKELEpfyneyLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  980 LKQQNYQQAssfppHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLR---EKNWEAMEALASTEKMLQDKVNK 1056
Cdd:PRK03918  652 LEKKYSEEE-----YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKeelEEREKAKKELEKLEKALERVEEL 726
                         570
                  ....*....|....*....
gi 384946988 1057 TSKERQQQVEAVELEAKEV 1075
Cdd:PRK03918  727 REKVKKYKALLKERALSKV 745
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
667-1022 1.04e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   667 ELEKMQQSVYVKDDKIRLLEEQLQ--HEISNKMEEFKILNDqnkalKLEVQKLQTLVSEqpnkdvVEQMEKCIQEKDEKL 744
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLErlRREREKAERYQALLK-----EKREYEGYELLKE------KEALERQKEAIERQL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   745 KTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKakQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKV 824
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   825 ANKEKTVQDLKQEIKALKEEIGNVQLEKAQqlsitsqvqeLQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN 904
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDK----------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   905 ESLKahvQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQN 984
Cdd:TIGR02169  395 EKLK---REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 384946988   985 YQQASSFpphEELLKVISEREKEISGLWNELDSLKDAV 1022
Cdd:TIGR02169  472 YDLKEEY---DRVEKELSKLQRELAEAEAQARASEERV 506
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1114-1351 1.31e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 1.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1114 EVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLR 1193
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1194 RENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELN----LLKAQLNETLTKL 1269
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAeaeeELEELAEELLEAL 392
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1270 RTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKE 1349
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                  ..
gi 384946988 1350 KE 1351
Cdd:COG1196   473 AL 474
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
628-1238 1.52e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 1.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  628 DHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND-Q 706
Cdd:PRK03918  158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElK 237
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  707 NKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETgLIQVATKEEELNAIRTENSSLTKEVQDLKAKQ 786
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRL 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  787 NDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQdLKQEIKALKEEIGNVQLEKAQqLSITSQVQELQ 866
Cdd:PRK03918  317 SRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHE-LYEEAKAKKEELERLKKRLTG-LTPEKLEKELE 394
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  867 NLLKGKEEQMNTMKAVLEEKeKDLANTGKWLQDLQEENESLKA------------HVQEVAQHNLKEVSS-ASQFEELEI 933
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARI-GELKKEIKELKKAIEELKKAKGkcpvcgrelteeHRKELLEEYTAELKRiEKELKEIEE 473
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  934 VLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQqassfppHEELLKVISEREKEISGLWN 1013
Cdd:PRK03918  474 KERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE-------YEKLKEKLIKLKGEIKSLKK 546
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1014 ELdslkdavehqrKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEvLKKLfpkvsvpsnlsYSE 1093
Cdd:PRK03918  547 EL-----------EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKE-LEPF-----------YNE 603
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1094 WLhgfekkakecmagtsgseEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWkvkvdeSHK 1173
Cdd:PRK03918  604 YL------------------ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY------SEE 659
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 384946988 1174 TIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ 1238
Cdd:PRK03918  660 EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVE 724
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
416-981 2.86e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 2.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  416 EAEIAHLKQENGILRDAVSNTTNQLESKQ---SAELNKLRqdyaRLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQE 492
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELpelREELEKLE----KEVKELEELKEEIEELEKELESLEGSKRKLEEKIRE 263
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  493 AERRWEEVqsyiRKRTAEHEAAQQDLQS-KFVAKE-NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQ 570
Cdd:PRK03918  264 LEERIEEL----KKEIEELEEKVKELKElKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEER 339
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  571 VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE-KDKQIKQTEDSLANERDHLTSKEEELKDIqnmnfllKA 649
Cdd:PRK03918  340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRlTGLTPEKLEKELEELEKAKEEIEEEISKI-------TA 412
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  650 EVQKLQALANEQAAAAHELEKMQQSVYV------KDDKIRLLEEQLQhEISNKMEEFKILNDQNKALKLEVQKLQTLVSE 723
Cdd:PRK03918  413 RIGELKKEIKELKKAIEELKKAKGKCPVcgreltEEHRKELLEEYTA-ELKRIEKELKEIEEKERKLRKELRELEKVLKK 491
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  724 QPNKDVVEQMEKCIQEKDEKLKTVE-ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAkqndqvsFASLVEELKKV 802
Cdd:PRK03918  492 ESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE-------LKKKLAELEKK 564
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  803 IHEKDGKIKSVEELLEAELLKvankekTVQDLKQEIKALkEEIGNVQLEkaqQLSITSQVQELQNLLKGKEEQmntmkav 882
Cdd:PRK03918  565 LDELEEELAELLKELEELGFE------SVEELEERLKEL-EPFYNEYLE---LKDAEKELEREEKELKKLEEE------- 627
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  883 LEEKEKDLANTGKWLQDLQEENESLKAHVQEvaqhnlkevssaSQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKL 962
Cdd:PRK03918  628 LDKAFEELAETEKRLEELRKELEELEKKYSE------------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKT 695
                         570
                  ....*....|....*....
gi 384946988  963 LQDVQDENKLFKSQIEQLK 981
Cdd:PRK03918  696 LEKLKEELEEREKAKKELE 714
PTZ00121 PTZ00121
MAEBL; Provisional
678-1329 3.38e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  678 KDDKIRLLEEQLQHEISNKMEEFKILNDQNKALklEVQKlqtlvSEQPNKDVVEQmekciqEKDEKLKTVEELLETGLIQ 757
Cdd:PTZ00121 1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAE--AVKK-----AEEAKKDAEEA------KKAEEERNNEEIRKFEEAR 1261
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  758 VATKEEELNAIRTENSSLTKEVQdlKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Cdd:PTZ00121 1262 MAHFARRQAAIKAEEARKADELK--KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAE 1339
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  838 IKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLAntgkwlQDLQEENESLKAHVQEVAqh 917
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA------DEAKKKAEEDKKKADELK-- 1411
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  918 nlKEVSSASQFEELeivlKEKENELKRVEAMLKERESdlSSKTKLLQDVQDENKlfKSQIEQLKQQNYQQASSFPPHEEL 997
Cdd:PTZ00121 1412 --KAAAAKKKADEA----KKKAEEKKKADEAKKKAEE--AKKADEAKKKAEEAK--KAEEAKKKAEEAKKADEAKKKAEE 1481
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  998 LKVISEREKEISGLWNELDSLKDAVEhQRKKNNDLR--EKNWEAMEALASTEKMLQDKVNKTSKERQqqveAVELEAKEV 1075
Cdd:PTZ00121 1482 AKKADEAKKKAEEAKKKADEAKKAAE-AKKKADEAKkaEEAKKADEAKKAEEAKKADEAKKAEEKKK----ADELKKAEE 1556
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1076 LKKLFPKVSVPSNLSYSEWLHGFEKKAKEcmagTSGSEEVKVLE-HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQ 1154
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRKAEE----AKKAEEARIEEvMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1155 RSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHlEMELEKAEMERSTYVTEVRELKDLL 1234
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEAEEAKKAEELKKKE 1711
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1235 TELQKKlddsySEAVRQNEELNLLKAQL--------NETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITV 1306
Cdd:PTZ00121 1712 AEEKKK-----AEELKKAEEENKIKAEEakkeaeedKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786
                         650       660
                  ....*....|....*....|...
gi 384946988 1307 IENSDVSPETESSEKETMSVSLN 1329
Cdd:PTZ00121 1787 EEDEKRRMEVDKKIKDIFDNFAN 1809
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
826-1322 3.72e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.15  E-value: 3.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  826 NKEKTVQDLKQEIKALKEEIGnvqlekaqqlSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENE 905
Cdd:PRK03918  162 NAYKNLGEVIKEIKRRIERLE----------KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK 231
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  906 SLKAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKL--FKSQIEQLKQQ 983
Cdd:PRK03918  232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLseFYEEYLDELRE 311
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  984 NYQQASSFpphEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNW---EAMEALASTEKMLQDKVNKTSKE 1060
Cdd:PRK03918  312 IEKRLSRL---EEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHElyeEAKAKKEELERLKKRLTGLTPEK 388
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1061 RQQQVEAVELEAKEVLKKLFPKVSVPSNLSYSEwlhGFEKKAKECMAGTSG---------------------SEEVKVLE 1119
Cdd:PRK03918  389 LEKELEELEKAKEEIEEEISKITARIGELKKEI---KELKKAIEELKKAKGkcpvcgrelteehrkelleeyTAELKRIE 465
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQ-----RSVEQEENKWKV-KVDESHKTIKQMQSSFTSSEQELERLR 1193
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKElaeqlKELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLK 545
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1194 RENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQ 1273
Cdd:PRK03918  546 KELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLE 625
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 384946988 1274 NERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKE 1322
Cdd:PRK03918  626 EELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRE 674
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
376-983 4.47e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 4.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   376 MKDRIGTLEKEHnvfQNKIHVSYQetqQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKlRQDY 455
Cdd:pfam15921  243 VEDQLEALKSES---QNKIELLLQ---QHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ-NSMY 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   456 ARLVNELtektgklqqeevqkknaEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Cdd:pfam15921  316 MRQLSDL-----------------ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQ 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   536 LTDTLVSKQQLEQRLMQLMESEQKRVNKE--------------ESLQMQVQDILEQNEALKAQIQ-QFHSQIAAQTSASV 600
Cdd:pfam15921  379 LQKLLADLHKREKELSLEKEQNKRLWDRDtgnsitidhlrrelDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNE 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   601 LAEELHKVIAekdkQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEvqkLQALANEQAAAAHELEKMQQSVYVKdd 680
Cdd:pfam15921  459 SLEKVSSLTA----QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS---LQEKERAIEATNAEITKLRSRVDLK-- 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   681 kirllEEQLQHeISNKMEEFKILNDQNKALKLEvqklqtlvseqpnkdvveqmekcIQEKDEKLKTVEELLETGLIQVAT 760
Cdd:pfam15921  530 -----LQELQH-LKNEGDHLRNVQTECEALKLQ-----------------------MAEKDKVIEILRQQIENMTQLVGQ 580
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   761 KEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKA 840
Cdd:pfam15921  581 HGRTAGAMQVEKAQLEKEINDRRLELQE---FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQ 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   841 LKEEIGNVQLEKAqqlSITSQVQELQNLLKGKEEQM----NTMKAVLEEKEKDLANTGKWLQDLqeenESLKAHVQEVAQ 916
Cdd:pfam15921  658 LLNEVKTSRNELN---SLSEDYEVLKRNFRNKSEEMetttNKLKMQLKSAQSELEQTRNTLKSM----EGSDGHAMKVAM 730
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 384946988   917 HNLKEVSSA-SQFEELEI---VLKEKENELKRVEAMLKERESDLSSKtklLQDVQDENKLFKSQIEQLKQQ 983
Cdd:pfam15921  731 GMQKQITAKrGQIDALQSkiqFLEEAMTNANKEKHFLKEEKNKLSQE---LSTVATEKNKMAGELEVLRSQ 798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
326-584 8.52e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 8.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  326 ELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERsnvvIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQ 405
Cdd:COG1196   268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER----RRELEERLEELEEELAELEEELEELEEELEELE 343
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  406 MKFQQVREQMEAEIAHLKQENGILRDAVsnttnQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQ 485
Cdd:COG1196   344 EELEEAEEELEEAEAELAEAEEALLEAE-----AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  486 LKVQLQEAERRWEEVqsyiRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Cdd:COG1196   419 LEEELEELEEALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
                         250
                  ....*....|....*....
gi 384946988  566 SLQMQVQDILEQNEALKAQ 584
Cdd:COG1196   495 LLLEAEADYEGFLEGVKAA 513
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
396-1063 1.26e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.59  E-value: 1.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   396 VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRdAVSNTTNQLESKQSaELNKLRQDYARLVNELteKTGKLQQEEVQ 475
Cdd:TIGR00606  207 MELKYLKQYKEKACEIRDQITSKEAQLESSREIVK-SYENELDPLKNRLK-EIEHNLSKIMKLDNEI--KALKSRKKQME 282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   476 KKNAEQAVTQLKVqLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLME 555
Cdd:TIGR00606  283 KDNSELELKMEKV-FQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   556 SEQKRVNKEESLQMQVQ-DILEQNEALKAQIQQFHSQIAAQTS-----ASVLAEELHKVIAEKDKQIKQTED-------S 622
Cdd:TIGR00606  362 HIRARDSLIQSLATRLElDGFERGPFSERQIKNFHTLVIERQEdeaktAAQLCADLQSKERLKQEQADEIRDekkglgrT 441
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   623 LANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQS----------VYVKDDKIRLLE------ 686
Cdd:TIGR00606  442 IELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNsltetlkkevKSLQNEKADLDRklrkld 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   687 ---EQLQHEISNKMEEFKILNDQNKA----LKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVA 759
Cdd:TIGR00606  522 qemEQLNHHTTTRTQMEMLTKDKMDKdeqiRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELA 601
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   760 TKEEELNAIRTENSSLTKEVQDLKAK-------QNDQVSFASLVEELKK------------------------------- 801
Cdd:TIGR00606  602 SLEQNKNHINNELESKEEQLSSYEDKlfdvcgsQDEESDLERLKEEIEKsskqramlagatavysqfitqltdenqsccp 681
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   802 --------------VIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLE----KAQQLSITSQVQ 863
Cdd:TIGR00606  682 vcqrvfqteaelqeFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEipelRNKLQKVNRDIQ 761
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   864 ELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQhnLKEVSSASQFEELEIVLKEKENELK 943
Cdd:TIGR00606  762 RLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK--LQGSDLDRTVQQVNQEKQEKQHELD 839
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   944 RVEAMLKEREsdlssktKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVE 1023
Cdd:TIGR00606  840 TVVSKIELNR-------KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS 912
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 384946988  1024 HQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQ 1063
Cdd:TIGR00606  913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
448-1332 3.61e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.12  E-value: 3.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   448 LNKLRQDYARLVNELTEKTGKLQQ-EEVQKKNAEQAVTQLKVQLQEAERRwEEVQSYIRKRTAEheaAQQDLQSKFVAKE 526
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESNElHEKQKFYLRQSVIDLQTKLQEMQME-RDAMADIRRRESQ---SQEDLRNQLQNTV 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEqkrvnkeESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASvLAEELH 606
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-------EGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRS-LGSAIS 223
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   607 KVIAEKDKQIKQTEDSLANERDHLTSKEEELKDiqNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQN--KIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   687 EQLQHEISNkmeefkilndQNKALKLEVQKLQTLVSEQPNkdvveqmekciqEKDEKLKTVEELLETGLIQVATKEEELN 766
Cdd:pfam15921  302 EIIQEQARN----------QNSMYMRQLSDLESTVSQLRS------------ELREAKRMYEDKIEELEKQLVLANSELT 359
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   767 AIRTENSSLTKEVQDLkakqNDQVsfaslvEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEig 846
Cdd:pfam15921  360 EARTERDQFSQESGNL----DDQL------QKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNME-- 427
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   847 nvqlekaqqlsitsqVQELQNLLKGKEE----QMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEV 922
Cdd:pfam15921  428 ---------------VQRLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE 492
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   923 SSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSfpphEELLKVIS 1002
Cdd:pfam15921  493 SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEK----DKVIEILR 568
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1003 EREKEISGLWNELDSLKDAVEHQRKK-NNDLREKNWEAMEAlasteKMLQDKVNKTSKERQQQVEAVELEAKEVLkklfp 1081
Cdd:pfam15921  569 QQIENMTQLVGQHGRTAGAMQVEKAQlEKEINDRRLELQEF-----KILKDKKDAKIRELEARVSDLELEKVKLV----- 638
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1082 kvsvpsnlsysewlhgfekkakecmagTSGSEEVKVLEHKLKEADEMHTLLQlecekyksvlaETEGILQKLQRSVEQEE 1161
Cdd:pfam15921  639 ---------------------------NAGSERLRAVKDIKQERDQLLNEVK-----------TSRNELNSLSEDYEVLK 680
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1162 NKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAemerstyVTEVRELKDLLTELQKKL 1241
Cdd:pfam15921  681 RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQ-------ITAKRGQIDALQSKIQFL 753
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1242 DDSYSEAvrqNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI--VKAAGDITVIENSDVSPETESS 1319
Cdd:pfam15921  754 EEAMTNA---NKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVanMEVALDKASLQFAECQDIIQRQ 830
                          890
                   ....*....|...
gi 384946988  1320 EKETMSVSLNQTV 1332
Cdd:pfam15921  831 EQESVRLKLQHTL 843
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
463-1276 3.80e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 3.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   463 TEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEvqsyIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLtdtlvs 542
Cdd:TIGR02169  205 REREKAERYQALLKEKREYEGYELLKEKEALERQKEA----IERQLASLEEELEKLTEEISELEKRLEEIEQLL------ 274
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   543 kQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQfhsqiaaqtsasvLAEELHKVIAEKDKQIKQTED 621
Cdd:TIGR02169  275 -EELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELED-------------AEERLAKLEAEIDKLLAEIEE 340
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   622 SlanerdhltskEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 701
Cdd:TIGR02169  341 L-----------EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD 409
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   702 ILNDQNKALKLEV----QKLQTLVSEQPN-KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLT 776
Cdd:TIGR02169  410 RLQEELQRLSEELadlnAAIAGIEAKINElEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   777 KEVQDLKAK----QNDQVSFASLVEELKKVIhekDGKIKSVEELLEAELLKVANKE------------KTVQDLKQEIKA 840
Cdd:TIGR02169  490 RELAEAEAQarasEERVRGGRAVEEVLKASI---QGVHGTVAQLGSVGERYATAIEvaagnrlnnvvvEDDAVAKEAIEL 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   841 LKEEignvQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKW-LQD--LQEENESLKAHVQEVAQH 917
Cdd:TIGR02169  567 LKRR----KAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvFGDtlVVEDIEAARRLMGKYRMV 642
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   918 NL--------------------KEVSSASQFEELEIV---LKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFK 974
Cdd:TIGR02169  643 TLegelfeksgamtggsraprgGILFSRSEPAELQRLrerLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   975 SQIEQLKQQnyqqassfppHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKV 1054
Cdd:TIGR02169  723 KEIEQLEQE----------EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1055 NKTSKERQQQVEAVELEAKEVLKklfpkvSVPSNLSYSEWLHGFEKKAKEcmagtsgSEEVKVLEHKLKEADEMHT--LL 1132
Cdd:TIGR02169  793 IPEIQAELSKLEEEVSRIEARLR------EIEQKLNRLTLEKEYLEKEIQ-------ELQEQRIDLKEQIKSIEKEieNL 859
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1133 QLECEKYKSVLAETEGILQKLqrsvEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEME 1212
Cdd:TIGR02169  860 NGKKEELEEELEELEAALRDL----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  1213 LEKAEMERSTYVTEVRELKDLLTELQKKLddsysEAVRQNEELNLL--------KAQLNETLTKLRTEQNER 1276
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAELQRVE-----EEIRALEPVNMLaiqeyeevLKRLDELKEKRAKLEEER 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
603-1300 2.42e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 2.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   603 EELHKVIAEKDKQIkqteDSLANERDHLTSKEEELKDIQNMNF-LLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDK 681
Cdd:TIGR02169  187 ERLDLIIDEKRQQL----ERLRREREKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   682 IRLLEEQLQHEIS------NKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGL 755
Cdd:TIGR02169  263 LEKRLEEIEQLLEelnkkiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   756 IQVATKEEELNAIRTENSSLTKEVQDLKAK-QNDQVSFASLVEELKKVIHEKDG---KIKSVEELLEAELLKVANKEKTV 831
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAElEEVDKEFAETRDELKDYREKLEKlkrEINELKRELDRLQEELQRLSEEL 422
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   832 QDLKQEIKALKEEIGNVQLEKaqqlsitsqvQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV 911
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEK----------EDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   912 QEVAQHNLKEVSSASQFEELEIVLKEKEN-------ELKRV-EAMLKERESDLSSKTKLLqdVQDENKLFKSQIEQLKQQ 983
Cdd:TIGR02169  493 AEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaQLGSVgERYATAIEVAAGNRLNNV--VVEDDAVAKEAIELLKRR 570
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   984 NYQQASSFPpheeLLKV-ISEREKEISGLWNELDSLKDAVEHQRKKNN-------------------------------- 1030
Cdd:TIGR02169  571 KAGRATFLP----LNKMrDERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvfgdtlvvedieaarrlmgkyrmvtleg 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1031 DLREKNwEAMEALASTEKMLQdKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNL--SYSEWLHGFEKKAKECMA- 1107
Cdd:TIGR02169  647 ELFEKS-GAMTGGSRAPRGGI-LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRldELSQELSDASRKIGEIEKe 724
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1108 GTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKW-KVKVDESHKTIKQMQSSFTSSE 1186
Cdd:TIGR02169  725 IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLE 804
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1187 QELERLRRENKDIEnlrREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETL 1266
Cdd:TIGR02169  805 EEVSRIEARLREIE---QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881
                          730       740       750
                   ....*....|....*....|....*....|....
gi 384946988  1267 TKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKA 1300
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
832-1300 5.31e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 5.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  832 QDLKQEIKALKEEIGNVQLEKAQQ--LSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDL--------ANTGKWLQDLQ 901
Cdd:COG4913   265 AAARERLAELEYLRAALRLWFAQRrlELLEAELEELRAELARLEAELERLEARLDALREELdeleaqirGNGGDRLEQLE 344
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  902 EENESLKAHVQEVAQhNLKEVssASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKlfkSQIEQLK 981
Cdd:COG4913   345 REIERLERELEERER-RRARL--EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAE---AALRDLR 418
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  982 QQnyqqassfppHEELLKVISEREKEISGLWNELDSLKDAVEHQ-RKKNNDLR-----------EKNWE-AMEALAST-- 1046
Cdd:COG4913   419 RE----------LRELEAEIASLERRKSNIPARLLALRDALAEAlGLDEAELPfvgelievrpeEERWRgAIERVLGGfa 488
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1047 ---------EKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLS-----YSEWLHGF-------------- 1098
Cdd:COG4913   489 ltllvppehYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDfkphpFRAWLEAElgrrfdyvcvdspe 568
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1099 ----EKKA--KECMAGTSGSEEVK----------VL----EHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRsvE 1158
Cdd:COG4913   569 elrrHPRAitRAGQVKGNGTRHEKddrrrirsryVLgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQE--R 646
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1159 QEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ 1238
Cdd:COG4913   647 REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE 726
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 384946988 1239 KKLDDSYSEAVRQNEELNL-LKAQLNETLTKLRTEQNERQKVA---GDLHKAQQSLELIQSKIVKA 1300
Cdd:COG4913   727 EELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVERELREnleERIDALRARLNRAEEELERA 792
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
349-781 7.14e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 50.82  E-value: 7.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  349 AATKDRCKQLTQEMmsEKERSNVVIARmKDRIGTLEKEHNVFQNKihvsyQETQQMQMKFQQVREQMEAEIAHLKQENGI 428
Cdd:PRK10929   19 AATAPDEKQITQEL--EQAKAAKTPAQ-AEIVEALQSALNWLEER-----KGSLERAKQYQQVIDNFPKLSAELRQQLNN 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  429 LRDAVSNttnqLESKQSAelNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRT 508
Cdd:PRK10929   91 ERDEPRS----VPPNMST--DALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLQTLG 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  509 AEHEAAQqdlQSKFVAKENEVQSLHSKLtdtlvskQQLEqrLMQLMESeqkrvNKEESLQMQVQDILEQNEALKAQIQQF 588
Cdd:PRK10929  165 TPNTPLA---QAQLTALQAESAALKALV-------DELE--LAQLSAN-----NRQELARLRSELAKKRSQQLDAYLQAL 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  589 HSQIAAQ---------TSASVLAE---ELHKVIAEKDKQIKQTEDSL---ANERDHLTSKE-----EELKDIQNMNFL-- 646
Cdd:PRK10929  228 RNQLNSQrqreaeralESTELLAEqsgDLPKSIVAQFKINRELSQALnqqAQRMDLIASQQrqaasQTLQVRQALNTLre 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  647 --------------LKAEVQKLQalaneqaaaahELEKMQQsvyVKDDKIRLLEEQLQHEisnkmeefKILNDQNKALKL 712
Cdd:PRK10929  308 qsqwlgvsnalgeaLRAQVARLP-----------EMPKPQQ---LDTEMAQLRVQRLRYE--------DLLNKQPQLRQI 365
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  713 EVQKLQTLVSEQpnkdvveqmeKCIQekDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLT---KEVQD 781
Cdd:PRK10929  366 RQADGQPLTAEQ----------NRIL--DAQLRTQRELLNSLLSGGDTLILELTKLKVANSQLEdalKEVNE 425
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
296-588 8.38e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 8.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   296 FSEDEALCVVDLLKEKSGVIQDALKKSSKgELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIAR 375
Cdd:pfam12128  597 ASEEELRERLDKAEEALQSAREKQAAAEE-QLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE 675
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   376 MKD----RIGTLEKEHNVFQNKIHVSYQETQ--------QMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESK 443
Cdd:pfam12128  676 RKDsaneRLNSLEAQLKQLDKKHQAWLEEQKeqkreartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW 755
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   444 QSAELNKLRQD---YARLVNELTEKTGKLQQEEVQkknaEQAVTQLKVQLQEaerRWEEVQSYIRKRTAEHEAAQQDLQS 520
Cdd:pfam12128  756 YKRDLASLGVDpdvIAKLKREIRTLERKIERIAVR----RQEVLRYFDWYQE---TWLQRRPRLATQLSNIERAISELQQ 828
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL---MESEQKRVNK------EESLQM-------QVQDILEQNEALKAQ 584
Cdd:pfam12128  829 QLARLIADTKLRRAKLEMERKASEKQQVRLSENlrgLRCEMSKLATlkedanSEQAQGsigerlaQLEDLKLKRDYLSES 908

                   ....
gi 384946988   585 IQQF 588
Cdd:pfam12128  909 VKKY 912
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
430-969 1.29e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  430 RDAVSNTTNQLESKQSAE----LNKLRQdyarlvnELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQsyir 505
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDlherLNGLES-------ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE---- 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  506 krtaEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEAL---- 581
Cdd:PRK02224  255 ----TLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELrdrl 330
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  582 ---KAQIQQFHSQI-AAQTSASVL---AEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDiqNMNFLLKAEVQkL 654
Cdd:PRK02224  331 eecRVAAQAHNEEAeSLREDADDLeerAEELREEAAELESELEEAREAVEDRREEIEELEEEIEE--LRERFGDAPVD-L 407
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  655 QALANEQAAAAHELEKMQQSVYVKDDKIRLLE------EQLQHE------------------ISNKMEEFKILNDQNKAL 710
Cdd:PRK02224  408 GNAEDFLEELREERDELREREAELEATLRTARerveeaEALLEAgkcpecgqpvegsphvetIEEDRERVEELEAELEDL 487
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  711 KLEVQKLQTLVSEQpnKDVVEQmEKCIQEKDEKLKTVEELLEtgliqvaTKEEELNAIRTENSSLTKEVQDLKAKQNDQV 790
Cdd:PRK02224  488 EEEVEEVEERLERA--EDLVEA-EDRIERLEERREDLEELIA-------ERRETIEEKRERAEELRERAAELEAEAEEKR 557
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVAnkekTVQDLKQEIKALKEEIGNVQlEKAQQLsitsqvQELQNLLK 870
Cdd:PRK02224  558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESLE----RIRTLLAAIADAEDEIERLR-EKREAL------AELNDERR 626
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  871 GKEEQMNTMKAVLEEKEKDLAntgkwLQDLQEENESLKAHVQEVAQhNLKEVssASQFEELEIVLKEKENELKRVEAmLK 950
Cdd:PRK02224  627 ERLAEKRERKRELEAEFDEAR-----IEEAREDKERAEEYLEQVEE-KLDEL--REERDDLQAEIGAVENELEELEE-LR 697
                         570
                  ....*....|....*....
gi 384946988  951 ERESDLSSKTKLLQDVQDE 969
Cdd:PRK02224  698 ERREALENRVEALEALYDE 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
920-1304 1.34e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  920 KEVSSASQFEELEIVLKEKENEL-----KRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQnyqqassfppH 994
Cdd:COG1196   207 RQAEKAERYRELKEELKELEAELlllklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE----------L 276
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  995 EELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEkmlqdkvnktskERQQQVEAVELEAKE 1074
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE------------EELEELEEELEELEE 344
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1075 VLKKLfpkvsvpsnlsysewlhgfekkakecmagtsgSEEVKVLEHKLKEADEmhtLLQLECEKYKSVLAETEGILQKLQ 1154
Cdd:COG1196   345 ELEEA--------------------------------EEELEEAEAELAEAEE---ALLEAEAELAEAEEELEELAEELL 389
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1155 RSVEQEENKwkvkvdesHKTIKQMQSSFTSSEQELERLRREnkdIENLRREREHLEMELEKAEMERSTYVTEVRELKDLL 1234
Cdd:COG1196   390 EALRAAAEL--------AAQLEELEEAEEALLERLERLEEE---LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1235 TELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDI 1304
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
442-643 1.50e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  442 SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDL--Q 519
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELeaQ 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  520 SKFVAKENEVQSLHSKLTDTLV-----SKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA 594
Cdd:COG4942   103 KEELAELLRALYRLGRQPPLALllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 384946988  595 QTSAsvlAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNM 643
Cdd:COG4942   183 LEEE---RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
757-983 1.53e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  757 QVATKEEELNAIRTENSSLTKEVQDLKAKQndqvsfASLVEELKKVihekDGKIKSVEELLEAELLKVANKEKTVQDLKQ 836
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEE------KALLKQLAAL----ERRIAALARRIRALEQELAALEAELAELEK 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  837 EIKALKEEIGNVQLEKAQQLSI---TSQVQELQNLLKGKEeqmntmkavLEEKEKDLANTGKWLQDLQEENESLKAHVQE 913
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRAlyrLGRQPPLALLLSPED---------FLDAVRRLQYLKYLAPARREQAEELRADLAE 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  914 VAQhnlKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQ 983
Cdd:COG4942   162 LAA---LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
829-1048 1.61e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  829 KTVQDLKQEIKALKEEIGNVQLEKAQQlsiTSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAAL---KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  909 AHVQEVaQHNLKEVSSA----SQFEELEIVLKEKENE--------LKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQ 976
Cdd:COG4942    97 AELEAQ-KEELAELLRAlyrlGRQPPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  977 IEQLKQQNYQQassfppHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEK 1048
Cdd:COG4942   176 LEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1113-1352 2.01e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 2.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1113 EEVKVLEHKLKEADEMHTLLQLEceKYKSVLAETEGILQKLQRSVEQEEnkwkVKVDESHKTIKQMQSSFTSSEQELERL 1192
Cdd:COG1196   213 ERYRELKEELKELEAELLLLKLR--ELEAELEELEAELEELEAELEELE----AELAELEAELEELRLELEELELELEEA 286
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1193 RrenKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTE 1272
Cdd:COG1196   287 Q---AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1273 QNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEH 1352
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
482-1288 2.34e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.20  E-value: 2.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   482 AVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKfvAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRV 561
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKL--KEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   562 NKEESLQMQVQDILEQNealkaQIQQFHSQIAAQTSASVLAEElhKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQ 641
Cdd:pfam02463  241 LLQELLRDEQEEIESSK-----QEIEKEEEKLAQVLKENKEEE--KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   642 NMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKddkirllEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLV 721
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIK-------REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   722 SEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASL----VE 797
Cdd:pfam02463  387 SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLlkdeLE 466
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMN 877
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIS 546
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEIVLKEKENE--LKRVEAMLKERESD 955
Cdd:pfam02463  547 TAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKatLEADEDDKRAKVVE 626
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   956 LSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREK 1035
Cdd:pfam02463  627 GILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1036 NWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECMAGTSGSEEV 1115
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1116 KVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRE 1195
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1196 NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNE 1275
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAD 946
                          810
                   ....*....|...
gi 384946988  1276 RQKVAGDLHKAQQ 1288
Cdd:pfam02463  947 EKEKEENNKEEEE 959
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
757-1311 2.65e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 2.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   757 QVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVS----FASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTeikkKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID 190
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   833 DLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENE----SLK 908
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikkQLS 270
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   909 AHVQEVAQHNLKEVSSASQFEELEIVLKEKENElkRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQ----N 984
Cdd:TIGR04523  271 EKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ--KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQisqlK 348
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   985 YQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKnweamealastekmlQDKVNKTSKERQQQ 1064
Cdd:TIGR04523  349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK---------------IQNQEKLNQQKDEQ 413
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1065 VEAVELEaKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLA 1144
Cdd:TIGR04523  414 IKKLQQE-KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK 492
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1145 ETEGILQKLQRSVEQEENKWKV---KVDESHKTIKQMQSSFTSSEQELERLRRE------NKDIENLRREREHLEMELEK 1215
Cdd:TIGR04523  493 SKEKELKKLNEEKKELEEKVKDltkKISSLKEKIEKLESEKKEKESKISDLEDElnkddfELKKENLEKEIDEKNKEIEE 572
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1216 AEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQS 1295
Cdd:TIGR04523  573 LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
                          570
                   ....*....|....*.
gi 384946988  1296 KIVKAAGDITVIENSD 1311
Cdd:TIGR04523  653 TIKEIRNKWPEIIKKI 668
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
730-1073 2.81e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 2.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   730 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKeVQDLKAKQND--QVSFASLVEELKKVIHEKD 807
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER-YQALLKEKREyeGYELLKEKEALERQKEAIE 243
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   808 GKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI----GNVQLE-KAQQLSITSQVQELQNLLKGKEEQMntmkav 882
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRvKEKIGELEAEIASLERSIAEKEREL------ 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   883 lEEKEKDLANTGKWLQDLQEENESLKahvQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKL 962
Cdd:TIGR02169  318 -EDAEERLAKLEAEIDKLLAEIEELE---REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   963 LQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEA 1042
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473
                          330       340       350
                   ....*....|....*....|....*....|.
gi 384946988  1043 LASTekmlQDKVNKTSKERQQQVEAVELEAK 1073
Cdd:TIGR02169  474 LKEE----YDRVEKELSKLQRELAEAEAQAR 500
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
305-1343 2.99e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.89  E-value: 2.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   305 VDLLK--EKSGVIQDALKKSSKGELTtlvHQLQEKDKLLAAVKEDAAAT-KDRCKQLTQEMMSEKERSNVVIARMKDRIG 381
Cdd:TIGR01612  623 IDLKKiiENNNAYIDELAKISPYQVP---EHLKNKDKIYSTIKSELSKIyEDDIDALYNELSSIVKENAIDNTEDKAKLD 699
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   382 TLekehnvfQNKIHVSYQETQQMQMkfqqvrEQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNE 461
Cdd:TIGR01612  700 DL-------KSKIDKEYDKIQNMET------ATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLNKILEDFKNKEKE 766
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   462 LTEKTGKLQQEEVQKKNAEQAVTQLKVQL-----------QEAERRWEEVQSYIR----------KRTAEHEAAQQDLQS 520
Cdd:TIGR01612  767 LSNKINDYAKEKDELNKYKSKISEIKNHYndqinidnikdEDAKQNYDKSKEYIKtisikedeifKIINEMKFMKDDFLN 846
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   521 K---FVAKEN----EVQSLHSKLTDtLVSKQQLEQRLMQLMESEqKRVNKEESLqmqvqdILEQNEALKAQIQQFHSQia 593
Cdd:TIGR01612  847 KvdkFINFENnckeKIDSEHEQFAE-LTNKIKAEISDDKLNDYE-KKFNDSKSL------INEINKSIEEEYQNINTL-- 916
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   594 aqtsasvlaeelhKVIAEKDKQIKQTEDSLANERDHLTSKEEEL----KDIQNMNFLLKAEVQKLQALANEQAAaahELE 669
Cdd:TIGR01612  917 -------------KKVDEYIKICENTKESIEKFHNKQNILKEILnkniDTIKESNLIEKSYKDKFDNTLIDKIN---ELD 980
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   670 KMqqsvyvkddkirLLEEQLQHEISNKMEEFKILNDQNKalKLEVQKLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVE 748
Cdd:TIGR01612  981 KA------------FKDASLNDYEAKNNELIKYFNDLKA--NLGKNKENMLYHQfDEKEKATNDIEQKIEDANKNIPNIE 1046
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   749 ELLETGLIQVAtkEEELNAIRTENSSLTKEVqdLKAKQNDQVSFASLVEELKkvIHEKDGKIKSVEELLEAELLKVANKE 828
Cdd:TIGR01612 1047 IAIHTSIYNII--DEIEKEIGKNIELLNKEI--LEEAEINITNFNEIKEKLK--HYNFDDFGKEENIKYADEINKIKDDI 1120
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   829 KTV-QDLKQEIKALkEEIGNVQLEKAQQlsITSQVQELQNL---------LKGKEEQMNTMKAVLEEKEKDLANTGKWLQ 898
Cdd:TIGR01612 1121 KNLdQKIDHHIKAL-EEIKKKSENYIDE--IKAQINDLEDVadkaisnddPEEIEKKIENIVTKIDKKKNIYDEIKKLLN 1197
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   899 DLQEEnESLKAHVQEVAQHNLKEVSSASQF--EELEIVLKEKENELKRVEAML------KERESDLSSKTKLLQDVQDEN 970
Cdd:TIGR01612 1198 EIAEI-EKDKTSLEEVKGINLSYGKNLGKLflEKIDEEKKKSEHMIKAMEAYIedldeiKEKSPEIENEMGIEMDIKAEM 1276
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   971 KLF------------------------KSQIEQLKQQNYQQASSFPPHEELLKVISEREK----------EISGLWN--E 1014
Cdd:TIGR01612 1277 ETFnishdddkdhhiiskkhdenisdiREKSLKIIEDFSEESDINDIKKELQKNLLDAQKhnsdinlylnEIANIYNilK 1356
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1015 LDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQD-KVNKTSKERQQQVEAVeLEAKEVlKKLFPKVSVPSN--LSY 1091
Cdd:TIGR01612 1357 LNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKiKDDINLEECKSKIEST-LDDKDI-DECIKKIKELKNhiLSE 1434
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1092 SEWLHGFEKKAKEcmagtsGSEEVKVLEHKLKEADEmHTLLQLECEKYKSVlAETEGILQKLQRSVEQEeNKWKVKVDES 1171
Cdd:TIGR01612 1435 ESNIDTYFKNADE------NNENVLLLFKNIEMADN-KSQHILKIKKDNAT-NDHDFNINELKEHIDKS-KGCKDEADKN 1505
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1172 HKTIKQMQSSFTSSEQELERLRRENKDIEnlrrerehLEMELEKAEMERSTYVTEVRELKDLLTelqkklddsySEAVRQ 1251
Cdd:TIGR01612 1506 AKAIEKNKELFEQYKKDVTELLNKYSALA--------IKNKFAKTKKDSEIIIKEIKDAHKKFI----------LEAEKS 1567
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1252 NEELNLLKAQlNETLTKLRTEQNERQKVAGDLhkaQQSLELIQSKIVKAAgDITVIENsDVSPETESSEKETMSVSLNQT 1331
Cdd:TIGR01612 1568 EQKIKEIKKE-KFRIEDDAAKNDKSNKAAIDI---QLSLENFENKFLKIS-DIKKKIN-DCLKETESIEKKISSFSIDSQ 1641
                         1130
                   ....*....|..
gi 384946988  1332 VTQLQQLLQAVN 1343
Cdd:TIGR01612 1642 DTELKENGDNLN 1653
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1190-1357 3.61e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 3.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1190 ERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKL 1269
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL 318
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1270 RTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKE 1349
Cdd:COG1196   319 EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL 398

                  ....*...
gi 384946988 1350 KEHYQVLE 1357
Cdd:COG1196   399 AAQLEELE 406
PRK12704 PRK12704
phosphodiesterase; Provisional
825-953 3.66e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.85  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  825 ANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLsitsqvQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN 904
Cdd:PRK12704   53 AIKKEALLEAKEEIHKLRNEFEKELRERRNEL------QKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQEL 126
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 384946988  905 ESLKAHVQE-VAQHN--LKEVSSASQFEELEIVLKEKENELKR-VEAMLKERE 953
Cdd:PRK12704  127 EKKEEELEElIEEQLqeLERISGLTAEEAKEILLEKVEEEARHeAAVLIKEIE 179
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
319-891 4.28e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 4.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   319 LKKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKIHVSY 398
Cdd:pfam12128  263 LHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETA 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   399 QETQQMQMKFQQVREQMEAEIAHLKQENGilrdAVSNTTNQLESKQSAELNKlrqDYARLVNEL-TEKTGKLQQEEVQKK 477
Cdd:pfam12128  343 AADQEQLPSWQSELENLEERLKALTGKHQ----DVTAKYNRRRSKIKEQNNR---DIAGIKDKLaKIREARDRQLAVAED 415
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   478 NAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHE------AAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLM 551
Cdd:pfam12128  416 DLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnqaTATPELLLQLENFDERIERAREEQEAANAEVERLQSELR 495
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   552 QLmesEQKRVNKEESLQMQVQDILEQNEALKAQIQQF----HSQIA-AQTSASVLAEELHKVIA-----------EKDKQ 615
Cdd:pfam12128  496 QA---RKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHfLRKEAPDWEQSIGKVISpellhrtdldpEVWDG 572
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   616 IKQTEDSLANERDHLtsKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN 695
Cdd:pfam12128  573 SVGGELNLYGVKLDL--KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN 650
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   696 KMEEFKILNDQNKALKLEVQklQTLVSEQpnKDVVEQMEKCIQEKDEKLKTVEELLEtgliqvATKEEELNAiRTENSSL 775
Cdd:pfam12128  651 ARLDLRRLFDEKQSEKDKKN--KALAERK--DSANERLNSLEAQLKQLDKKHQAWLE------EQKEQKREA-RTEKQAY 719
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   776 TKEVQDLKAKQndqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQ 855
Cdd:pfam12128  720 WQVVEGALDAQ-----LALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEV 794
                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 384946988   856 LSITSQVQELQNLLKGK-EEQMNTMKAVLEEKEKDLA 891
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRlATQLSNIERAISELQQQLA 831
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
530-1210 6.60e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 6.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   530 QSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVI 609
Cdd:TIGR00618  190 KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARI 269
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   610 AEKDKQIKQTEDSLA--NERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEE 687
Cdd:TIGR00618  270 EELRAQEAVLEETQEriNRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   688 QLQHEISNKMEefkilndQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQekdeKLKTVEELLETGLIQVATKEEELNA 767
Cdd:TIGR00618  350 LHSQEIHIRDA-------HEVATSIREISCQQHTLTQHIHTLQQQKTTLTQ----KLQSLCKELDILQREQATIDTRTSA 418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   768 IRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE---KTVQDLKQEIKALKEE 844
Cdd:TIGR00618  419 FRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLARLLE 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   845 IGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSS 924
Cdd:TIGR00618  499 LQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQC 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   925 ASQF-EELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDE-NKLFKSQIEQLKQQNYQQASSfPPHEELLKVIS 1002
Cdd:TIGR00618  579 DNRSkEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEqDLQDVRLHLQQCSQELALKLT-ALHALQLTLTQ 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1003 EREKEISGLWNELDSLK--------DAVEHQRKKNNDLREKNWEAMEALASTEKMLQD------KVNKTSKERQQQVEAV 1068
Cdd:TIGR00618  658 ERVREHALSIRVLPKELlasrqlalQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEydrefnEIENASSSLGSDLAAR 737
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1069 ELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEG 1148
Cdd:TIGR00618  738 EDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDED 817
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  1149 ILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLE 1210
Cdd:TIGR00618  818 ILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLN 879
COG5022 COG5022
Myosin heavy chain [General function prediction only];
730-1322 7.67e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.38  E-value: 7.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  730 VEQMEKCIQEKDEKLKTVEELLETG--LIQVAT--KEEELNAIRTENSSLTKEVQDLK-AKQNDQVSFASL--VEELKKV 802
Cdd:COG5022   877 VELAERQLQELKIDVKSISSLKLVNleLESEIIelKKSLSSDLIENLEFKTELIARLKkLLNNIDLEEGPSieYVKLPEL 956
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  803 --IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGnvqlekaqqlSITSQVQELQNLLKGKEEqMNTMK 880
Cdd:COG5022   957 nkLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELA----------ELSKQYGALQESTKQLKE-LPVEV 1025
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  881 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNlKEVSSASQFEELEIVLKEKENELKRVEAMLKE-RESDLSSK 959
Cdd:COG5022  1026 AELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQ-ARYKALKLRRENSLLDDKQLYQLESTENLLKTiNVKDLEVT 1104
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  960 TKLLqdVQDENKLFKSQIEQLKQQNYQQASSFPPheELLKVISEREKEISGLWNELDSLKDAvehqrkknNDLREKNWEA 1039
Cdd:COG5022  1105 NRNL--VKPANVLQFIVAQMIKLNLLQEISKFLS--QLVNTLEPVFQKLSVLQLELDGLFWE--------ANLEALPSPP 1172
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1040 MEALASTEKMLQDKVNKT-SKERQQQVEAVELEAKEVLKKlfpkvsvpsnlSYSEWLHGFEKK--AKECMAGTSGSEevk 1116
Cdd:COG5022  1173 PFAALSEKRLYQSALYDEkSKLSSSEVNDLKNELIALFSK-----------IFSGWPRGDKLKklISEGWVPTEYST--- 1238
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1117 vlehKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTS---SEQELERLR 1193
Cdd:COG5022  1239 ----SLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRtkaSSLRWKSAT 1314
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1194 RENKDIENL-----RREREHLEMELEkaEMERSTYVTEVRelKDLLTELQKKLDDSYSEavrQNEELNLLKAQLNETLTK 1268
Cdd:COG5022  1315 EVNYNSEELddwcrEFEISDVDEELE--ELIQAVKVLQLL--KDDLNKLDELLDACYSL---NPAEIQNLKSRYDPADKE 1387
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 384946988 1269 LRTEQNERQKVAGDLHKAQQSLE-LIQSKIVKAAGDITVIENSDVSPETESSEKE 1322
Cdd:COG5022  1388 NNLPKEILKKIEALLIKQELQLSlEGKDETEVHLSEIFSEEKSLISLDRNSIYKE 1442
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
826-1049 8.18e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 8.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  826 NKEKTVQDLKQ----EIKALKEEIGNVQLEKAQQLSIT-----SQVQELQNLLKGKEEQMNTMK-----AVLEEKEKDLA 891
Cdd:PRK05771   17 YKDEVLEALHElgvvHIEDLKEELSNERLRKLRSLLTKlsealDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  892 NTGKWLQDLQEENESLKAHVQEVaQHNLKEVSSASQFEELEIVLKEKEN---ELKRVEAMLKERESDLSSKTKLLQDVQD 968
Cdd:PRK05771   97 KIEKEIKELEEEISELENEIKEL-EQEIERLEPWGNFDLDLSLLLGFKYvsvFVGTVPEDKLEELKLESDVENVEYISTD 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  969 ENKLF----------KSQIEQLKQQNYQQASsFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDL------ 1032
Cdd:PRK05771  176 KGYVYvvvvvlkelsDEVEEELKKLGFERLE-LEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEEllalye 254
                         250       260
                  ....*....|....*....|..
gi 384946988 1033 -----REKNwEAMEALASTEKM 1049
Cdd:PRK05771  255 yleieLERA-EALSKFLKTDKT 275
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
389-1011 1.19e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 46.74  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   389 VFQNKIHVSYQETQQMQMKFQQVREQMEA--EIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNEL---- 462
Cdd:pfam10174   57 VLKEQYRVTQEENQHLQLTIQALQDELRAqrDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELfllr 136
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   463 ------------TEKTGKLQQEEVQK-----------KNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQ 519
Cdd:pfam10174  137 ktleemelrietQKQTLGARDESIKKllemlqskglpKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELH 216
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   520 SKF-VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQM-QVQDILEQNEA-------LKAQIQQFHS 590
Cdd:pfam10174  217 RRNqLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTeDREEEIKQMEVykshskfMKNKIDQLKQ 296
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   591 QIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLaneRDHLTSKEEELKDIQN-----------MNFLLKAEVQKLQALAN 659
Cdd:pfam10174  297 ELSKKESELLALQTKLETLTNQNSDCKQHIEVL---KESLTAKEQRAAILQTevdalrlrleeKESFLNKKTKQLQDLTE 373
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   660 EQAAAAHELEKMQQSVYVKDDKIRLleeqLQHEISNKMEEFKILNDQNKALKLEVQKLQTlvsEQPNKD-VVEQMEKCIQ 738
Cdd:pfam10174  374 EKSTLAGEIRDLKDMLDVKERKINV----LQKKIENLQEQLRDKDKQLAGLKERVKSLQT---DSSNTDtALTTLEEALS 446
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   739 EKDeklKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEE----LKKVIHEKDGKIKSVE 814
Cdd:pfam10174  447 EKE---RIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEhassLASSGLKKDSKLKSLE 523
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   815 ----------ELLEAELLKVANKEKT----------VQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLlkgKEE 874
Cdd:pfam10174  524 iaveqkkeecSKLENQLKKAHNAEEAvrtnpeindrIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKND---KDK 600
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   875 QMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVA---QHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKE 951
Cdd:pfam10174  601 KIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEArrrEDNLADNSQQLQLEELMGALEKTRQELDATKARLSS 680
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   952 RESDLSSKTKLLQDVQDENKLFKSQIEQLKQqnyqqassfpphEELLKVISEREKEISGL 1011
Cdd:pfam10174  681 TQQSLAEKDGHLTNLRAERRKQLEEILEMKQ------------EALLAAISEKDANIALL 728
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
411-641 1.30e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  411 VREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDyarlvNELTEKTGKLQQEEVQKKNAEQAVTQLKVQL 490
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEEAE-AALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  491 QEAERRWEEVQSYIRKRTAEHEAAQQDlqskfvakeNEVQSLHSKLtdtlvskQQLEQRLMQLmeseQKRVNKEESlqmQ 570
Cdd:COG3206   236 AEAEARLAALRAQLGSGPDALPELLQS---------PVIQQLRAQL-------AELEAELAEL----SARYTPNHP---D 292
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 384946988  571 VQDILEQNEALKAQIQQFHSQIAAQTSASVlaeelhKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQ 641
Cdd:COG3206   293 VIALRAQIAALRAQLQQEAQRILASLEAEL------EALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1123-1357 1.88e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1123 KEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENK----- 1197
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAkleae 330
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1198 ------DIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRT 1271
Cdd:TIGR02169  331 idkllaEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDR 410
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1272 EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                   ....*.
gi 384946988  1352 HYQVLE 1357
Cdd:TIGR02169  491 ELAEAE 496
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
685-1020 2.31e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.81  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   685 LEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQtlvsEQPNKDVVeQMEKCIQEK-DEKLKTVEELLETGLIQVATKEE 763
Cdd:TIGR01612  534 IKAKLYKEIEAGLKESYELAKNWKKLIHEIKKEL----EEENEDSI-HLEKEIKDLfDKYLEIDDEIIYINKLKLELKEK 608
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   764 ELNaIRTENSSLTKEVqdlkakqndqvsfaslveELKKVIHEKDGKIKSVEELLEAELLK-VANKEKTVQDLKQEikalk 842
Cdd:TIGR01612  609 IKN-ISDKNEYIKKAI------------------DLKKIIENNNAYIDELAKISPYQVPEhLKNKDKIYSTIKSE----- 664
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   843 eeignvqLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLqeENESLKAHVQEVaqHNLKEV 922
Cdd:TIGR01612  665 -------LSKIYEDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNM--ETATVELHLSNI--ENKKNE 733
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   923 SSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS-----------SF 991
Cdd:TIGR01612  734 LLDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYNDQINidnikdedakqNY 813
                          330       340
                   ....*....|....*....|....*....
gi 384946988   992 PPHEELLKVISEREKEISGLWNELDSLKD 1020
Cdd:TIGR01612  814 DKSKEYIKTISIKEDEIFKIINEMKFMKD 842
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1113-1357 2.87e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 2.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1113 EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERL 1192
Cdd:COG1196   260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1193 RRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTE 1272
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1273 QNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIensdvspETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEH 1352
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAEL-------EEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                  ....*
gi 384946988 1353 YQVLE 1357
Cdd:COG1196   493 LLLLL 497
46 PHA02562
endonuclease subunit; Provisional
970-1259 3.83e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 3.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  970 NKLFKSQIEQLKQQnyqqassfppheellkvISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKM 1049
Cdd:PHA02562  169 DKLNKDKIRELNQQ-----------------IQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKT 231
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1050 LQDKVNktskERQQQVEAVELEAKEV---LKKLFPK-VSVPSNLSYSEWLHGFEKKAKECMAGTSGseevkvlehkLKEA 1125
Cdd:PHA02562  232 IKAEIE----ELTDELLNLVMDIEDPsaaLNKLNTAaAKIKSKIEQFQKVIKMYEKGGVCPTCTQQ----------ISEG 297
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1126 DEMhtllqleCEKYKSVLAETEGILQKLQRSVEQEENKwKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENlrre 1205
Cdd:PHA02562  298 PDR-------ITKIKDKLKELQHSLEKLDTAIDELEEI-MDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKA---- 365
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 384946988 1206 rehlemELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLK 1259
Cdd:PHA02562  366 ------AIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLK 413
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
668-1291 5.00e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 5.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEfKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTV 747
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLES-ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEI 260
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  748 EELLETgliqVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLveelkkviheKDGKIKSVEELLEAELLKVANK 827
Cdd:PRK02224  261 EDLRET----IAETEREREELAEEVRDLRERLEELEEERDDLLAEAGL----------DDADAEAVEARREELEDRDEEL 326
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  828 EKTVQDLKQEIKALKEEIGnvqlekaqqlSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAE----------SLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL 396
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  908 KAHVQEvaqhnlkevsSASQFEELEIVLKEKENELKRVEAMLKERESDLSSktklLQDVQDENKLFksqIEQLKQQNYQQ 987
Cdd:PRK02224  397 RERFGD----------APVDLGNAEDFLEELREERDELREREAELEATLRT----ARERVEEAEAL---LEAGKCPECGQ 459
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  988 ASSFPPHEEllkVISEREKEISGLWNELDSLKDAVEHqrkknndlREKNWEAMEALASTEKMLQdkvnkTSKERQQQVEA 1067
Cdd:PRK02224  460 PVEGSPHVE---TIEEDRERVEELEAELEDLEEEVEE--------VEERLERAEDLVEAEDRIE-----RLEERREDLEE 523
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1068 VELEAKEvlkklfpkvsvpsnlsysewlhGFEKKAKECmagTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETE 1147
Cdd:PRK02224  524 LIAERRE----------------------TIEEKRERA---EELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELN 578
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1148 GILQKLQRSVEQeenkwkvkvdeshktikqmqssftsseqeLERLRRENKDIENLRREREHLEMELE-KAEM--ERSTYV 1224
Cdd:PRK02224  579 SKLAELKERIES-----------------------------LERIRTLLAAIADAEDEIERLREKREaLAELndERRERL 629
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 384946988 1225 TEVRELKDlltELQKKLDDSYSEAVRQN-EELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLE 1291
Cdd:PRK02224  630 AEKRERKR---ELEAEFDEARIEEAREDkERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE 694
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
377-556 5.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 5.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  377 KDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEA-------------------EIAHLKQEngilRDAVSNTT 437
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswdeidvasaerEIAELEAE----LERLDASS 684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  438 NQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYI---RKRTAEHEAA 514
Cdd:COG4913   685 DDLAALE-EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleeRFAAALGDAV 763
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 384946988  515 QQDLQSKFvakENEVQSLHSKLtdtlvskQQLEQRLMQLMES 556
Cdd:COG4913   764 ERELRENL---EERIDALRARL-------NRAEEELERAMRA 795
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
829-1297 5.67e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 5.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  829 KTVQDLKQEIKALKEEIgnvqlekAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENEslk 908
Cdd:COG4717    64 RKPELNLKELKELEEEL-------KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE--- 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  909 ahvqevaqhnlkevssasqFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQa 988
Cdd:COG4717   134 -------------------LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE- 193
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  989 ssfppheellkvISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKnweamEALASTEKMLQDKVNKTSKERQQQVEAV 1068
Cdd:COG4717   194 ------------LQDLAEELEELQQRLAELEEELEEAQEELEELEEE-----LEQLENELEAAALEERLKEARLLLLIAA 256
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1069 ELEAKEVLKKLFPKVSVP------SNLSYSEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQL---ECEKY 1139
Cdd:COG4717   257 ALLALLGLGGSLLSLILTiagvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSP 336
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1140 KSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ-MQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKA-- 1216
Cdd:COG4717   337 EELLELLDRIEELQELLREAEELEEELQLEELEQEIAAlLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELlg 416
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1217 EMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNE-----TLTKLRTEQNERQKVAGDLHKAQQSLE 1291
Cdd:COG4717   417 ELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQleedgELAELLQELEELKAELRELAEEWAALK 496

                  ....*.
gi 384946988 1292 LIQSKI 1297
Cdd:COG4717   497 LALELL 502
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
412-621 5.69e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 5.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  412 REQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY-------ARLVN-ELTEKTGKLQQEEVQKKNAEQAV 483
Cdd:NF012221 1564 KERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQrdaileeSRAVTkELTTLAQGLDALDSQATYAGESG 1643
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  484 TQLKVQLqeAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKlTDTLVskQQLEQRLMQLMESEQKRVNK 563
Cdd:NF012221 1644 DQWRNPF--AGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAK-SEAGV--AQGEQNQANAEQDIDDAKAD 1718
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  564 EESLQMQVqdILEQNEALKAQIQQFHS----QIAAQTSASVLAEELHKVIAEKdKQIKQTED 621
Cdd:NF012221 1719 AEKRKDDA--LAKQNEAQQAESDANAAandaQSRGEQDASAAENKANQAQADA-KGAKQDES 1777
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
824-1242 7.28e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 7.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   824 VANKEKTVQDLKQEIKALKEEIGNVQL---EKAQQLSITS----QVQELQNLLKGKEEQMNTMKAV-LEEKEKDLANTGK 895
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRrereKAERYQALLKEKREYEGYELLKeKEALERQKEAIER 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   896 WLQDLQEENESLKAHVQEVAQhnlkevssasQFEELEIVLKEKENELKRV----EAMLKERESDLSSKTKLLQDVQDENK 971
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEK----------RLEEIEQLLEELNKKIKDLgeeeQLRVKEKIGELEAEIASLERSIAEKE 314
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   972 lfksqiEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKnweaMEALASTEKMLQ 1051
Cdd:TIGR02169  315 ------RELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE----LEEVDKEFAETR 384
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1052 DKVnktsKERQQQVEAVELEAKEVLKKLFPKVsvpsnlsysewlhgfEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTL 1131
Cdd:TIGR02169  385 DEL----KDYREKLEKLKREINELKRELDRLQ---------------EELQRLSEELADLNAAIAGIEAKINELEEEKED 445
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1132 LQLECEKyksvlaetegilqklqrsveQEENkwkvkvdeshktIKQMQSSFTSSEQELERLRRENKDIEnlrREREHLEM 1211
Cdd:TIGR02169  446 KALEIKK--------------------QEWK------------LEQLAADLSKYEQELYDLKEEYDRVE---KELSKLQR 490
                          410       420       430
                   ....*....|....*....|....*....|.
gi 384946988  1212 ELEKAEMERSTYVTEVRELKDLLTELQKKLD 1242
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQ 521
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1142-1351 8.01e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 8.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1142 VLAETEGILQKLQRSVEQEENKWKVKVDESHKtikQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEmers 1221
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELREL---ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELE---- 266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1222 tyvTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAA 1301
Cdd:TIGR02168  267 ---EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELE 343
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 384946988  1302 GDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
PRK00106 PRK00106
ribonuclease Y;
825-967 8.49e-04

ribonuclease Y;


Pssm-ID: 178867 [Multi-domain]  Cd Length: 535  Bit Score: 43.70  E-value: 8.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  825 ANKEKTVQDLKQEIKALKEEIGNVQLEKAQQL-SITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEE 903
Cdd:PRK00106   68 ALKKELLLEAKEEARKYREEIEQEFKSERQELkQIESRLTERATSLDRKDENLSSKEKTLESKEQSLTDKSKHIDEREEQ 147
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988  904 NESLkahvQEVAQHNLKEVSSASQFEELEIVLKEKENEL--------KRVEAMLKEReSDLSSKTKLLQDVQ 967
Cdd:PRK00106  148 VEKL----EEQKKAELERVAALSQAEAREIILAETENKLtheiatriREAEREVKDR-SDKMAKDLLAQAMQ 214
mukB PRK04863
chromosome partition protein MukB;
468-638 8.72e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 8.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  468 KLQQEEVQKKNAEQaVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSkfvakENEVQSLHskltdtlvskQQLE 547
Cdd:PRK04863  501 LLRRLREQRHLAEQ-LQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDD-----EDELEQLQ----------EELE 564
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  548 QRLMQLmeSEQKRVNKEEslQMQVQDILEQneaLKAQIQQFHSQ----IAAQTSASVLAEELHKVIAEK---DKQIKQT- 619
Cdd:PRK04863  565 ARLESL--SESVSEARER--RMALRQQLEQ---LQARIQRLAARapawLAAQDALARLREQSGEEFEDSqdvTEYMQQLl 637
                         170       180
                  ....*....|....*....|.
gi 384946988  620 --EDSLANERDHLTSKEEELK 638
Cdd:PRK04863  638 erERELTVERDELAARKQALD 658
PRK12704 PRK12704
phosphodiesterase; Provisional
929-1026 9.24e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 9.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  929 EELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQassfppHEELLKVISEREKE- 1007
Cdd:PRK12704   71 NEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKK------EEELEELIEEQLQEl 144
                          90       100
                  ....*....|....*....|....*..
gi 384946988 1008 --ISGLWNE------LDSLKDAVEHQR 1026
Cdd:PRK12704  145 erISGLTAEeakeilLEKVEEEARHEA 171
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
731-1023 9.50e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 43.76  E-value: 9.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  731 EQMEK--CIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN-SSLTKEVQDLKAKQNDQVSFASLVEELKKVIhekd 807
Cdd:PRK05771    4 VRMKKvlIVTLKSYKDEVLEALHELGVVHIEDLKEELSNERLRKlRSLLTKLSEALDKLRSYLPKLNPLREEKKKV---- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  808 gKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKeeqmnTMKAVLEEKE 887
Cdd:PRK05771   80 -SVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDLSLLLGFK-----YVSVFVGTVP 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  888 KDlantgkwlQDLQEENESLKAHVQEVAQHNLKE----VSSASQFEELEIVLkeKENELKRVEAmlkereSDLSSKTKLL 963
Cdd:PRK05771  154 ED--------KLEELKLESDVENVEYISTDKGYVyvvvVVLKELSDEVEEEL--KKLGFERLEL------EEEGTPSELI 217
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  964 QDVQDENKLFKSQIEQLKqqnyqqassfpphEELLKVISEREKEISGLWNELDSLKDAVE 1023
Cdd:PRK05771  218 REIKEELEEIEKERESLL-------------EELKELAKKYLEELLALYEYLEIELERAE 264
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
561-1065 1.09e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  561 VNKEESLQMQVQDILEQNEALKAQIQQF-HSQIAAQTSASvlAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKD 639
Cdd:COG4717    15 RDRTIEFSPGLNVIYGPNEAGKSTLLAFiRAMLLERLEKE--ADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAE 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQsVYVKDDKIRLLEEQLQH------EISNKMEEFKILNDQNKALKLE 713
Cdd:COG4717    93 LQEELEELEEELEELEAELEELREELEKLEKLLQ-LLPLYQELEALEAELAElperleELEERLEELRELEEELEELEAE 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  714 VQKLQTLVSEQPNkDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQ---- 789
Cdd:COG4717   172 LAELQEELEELLE-QLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKearl 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  790 --------VSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLE-----KAQQL 856
Cdd:COG4717   251 llliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEEleellAALGL 330
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  857 SITSQVQELQNLLKgKEEQMNTMKAVLEEKEKDLAntgkwLQDLQEENESLKAHVQevaqhnlkeVSSASQFEELEIVLK 936
Cdd:COG4717   331 PPDLSPEELLELLD-RIEELQELLREAEELEEELQ-----LEELEQEIAALLAEAG---------VEDEEELRAALEQAE 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  937 EKENELKRVEAMLKERESDLSSKTKLLQDVQDENklFKSQIEQLKQqnyQQASSFPPHEELLKVISEREKEISGLWN--E 1014
Cdd:COG4717   396 EYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEE---ELEELEEELEELREELAELEAELEQLEEdgE 470
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 384946988 1015 LDSLKDAVEHQRKKNNDLREKNweamEALASTEKMLQDKVNKTSKERQQQV 1065
Cdd:COG4717   471 LAELLQELEELKAELRELAEEW----AALKLALELLEEAREEYREERLPPV 517
PRK01156 PRK01156
chromosome segregation protein; Provisional
774-1308 1.50e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  774 SLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIK---ALKEEIGNVQL 850
Cdd:PRK01156  177 MLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNelsSLEDMKNRYES 256
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  851 EKAQQLSITSQVQELQNLLKGKEEQMN--TMKAVLEEKEK--DLANTGKWLQDLQEENESLKAHVQEVaQHNLKEVSSAS 926
Cdd:PRK01156  257 EIKTAESDLSMELEKNNYYKELEERHMkiINDPVYKNRNYinDYFKYKNDIENKKQILSNIDAEINKY-HAIIKKLSVLQ 335
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  927 QFEELEIVLKEKENELKRVEAMLKERESDLSS--------KTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELL 998
Cdd:PRK01156  336 KDYNDYIKKKSRYDDLNNQILELEGYEMDYNSylksieslKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEIN 415
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  999 KVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKER---QQQVEAVELEAKEV 1075
Cdd:PRK01156  416 VKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIINHYNEKKsrlEEKIREIEIEVKDI 495
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1076 LKKLFPKVSVPSNLSYSEwlhgFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAEtegilqklqr 1155
Cdd:PRK01156  496 DEKIVDLKKRKEYLESEE----INKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLE---------- 561
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1156 SVEQEENKW-KVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIE-NLRREREHLEMELEKAEMERSTY---VTEVREL 1230
Cdd:PRK01156  562 DLDSKRTSWlNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEiGFPDDKSYIDKSIREIENEANNLnnkYNEIQEN 641
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1231 KDLLTELQKKLDDSYSEAVRQNE---ELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVI 1307
Cdd:PRK01156  642 KILIEKLRGKIDNYKKQIAEIDSiipDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDI 721

                  .
gi 384946988 1308 E 1308
Cdd:PRK01156  722 N 722
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-532 1.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  412 REQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA-------EQAVT 484
Cdd:COG4913   304 LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALglplpasAEEFA 383
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 384946988  485 QLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSL 532
Cdd:COG4913   384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
737-915 1.84e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 1.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  737 IQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQvsfASLVEELKKVIHEKDGKIKSVEel 816
Cdd:COG1579    12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRL---ELEIEEVEARIKKYEEQLGNVR-- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  817 leaellkvanKEKTVQDLKQEIKALKEEIGnvQLEKaQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTgkw 896
Cdd:COG1579    87 ----------NNKEYEALQKEIESLKRRIS--DLED-EILELMERIEELEEELAELEAELAELEAELEEKKAELDEE--- 150
                         170
                  ....*....|....*....
gi 384946988  897 LQDLQEENESLKAHVQEVA 915
Cdd:COG1579   151 LAELEAELEELEAEREELA 169
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
898-1074 2.04e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  898 QDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQI 977
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  978 EQLKQQNYQQASSFPP------------------HEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEA 1039
Cdd:COG4942   107 AELLRALYRLGRQPPLalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 384946988 1040 MEALASTEKMLQDKVNKTSKER-QQQVEAVELEAKE 1074
Cdd:COG4942   187 RAALEALKAERQKLLARLEKELaELAAELAELQQEA 222
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1119-1260 2.05e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1119 EHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE--QEENK-WKVKVDESHKTIKQMQSSFTSSEQELERLRRE 1195
Cdd:COG2433   384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVErlEAEVEeLEAELEEKDERIERLERELSEARSEERREIRK 463
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384946988 1196 NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ-------KKLDDSYSEAVRQNEELNLLKA 1260
Cdd:COG2433   464 DREISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHsgelvpvKVVEKFTKEAIRRLEEEYGLKE 535
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1186-1357 2.53e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 2.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1186 EQELERLRrenkDIEN-LRREREHLEMELEKAEmerstyvtEVRELKDLLTELQ-----KKLDDSYSEAVRQNEELNLLK 1259
Cdd:COG1196   185 EENLERLE----DILGeLERQLEPLERQAEKAE--------RYRELKEELKELEaelllLKLRELEAELEELEAELEELE 252
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1260 AQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLL 1339
Cdd:COG1196   253 AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL 332
                         170
                  ....*....|....*...
gi 384946988 1340 QAVNQQLTKEKEHYQVLE 1357
Cdd:COG1196   333 EELEEELEELEEELEEAE 350
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
925-1228 3.17e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   925 ASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKviSE 1003
Cdd:pfam17380  333 AAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMErQQKNERVRQELEAARKVKILE--EE 410
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1004 REKEISGLWNELDSLKDAVEHQRKknndlreknwEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKV 1083
Cdd:pfam17380  411 RQRKIQQQKVEMEQIRAEQEEARQ----------REVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELE 480
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1084 SVPSnlsysewlhgfEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEgilqklQRSVEQEENK 1163
Cdd:pfam17380  481 KEKR-----------DRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEE------RRREAEEERR 543
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 384946988  1164 WKVKVDESHKTIKQMQSSfTSSEQELERLRRENKDIenlrreREHLEMELEKAEMERSTYVTEVR 1228
Cdd:pfam17380  544 KQQEMEERRRIQEQMRKA-TEERSRLEAMEREREMM------RQIVESEKARAEYEATTPITTIK 601
PLN02939 PLN02939
transferase, transferring glycosyl groups
468-801 3.24e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 3.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  468 KLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLhsKLTDTLVSKQQLE 547
Cdd:PLN02939   64 KLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDF--QLEDLVGMIQNAE 141
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  548 QRLMQLmesEQKRVNKEEslqmQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA--EELHKVIAEK--DKQIKQTEDSL 623
Cdd:PLN02939  142 KNILLL---NQARLQALE----DLEKILTEKEALQGKINILEMRLSETDARIKLAaqEKIHVEILEEqlEKLRNELLIRG 214
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  624 ANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLqheISNKMEEFKIL 703
Cdd:PLN02939  215 ATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKF---IVAQEDVSKLS 291
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  704 NDQNKALKLEVQKLQTLVSEQPNKdvVEQMEKCIQEKDEKLKTVEELLET--------------GLIQVATK--EEELNA 767
Cdd:PLN02939  292 PLQYDCWWEKVENLQDLLDRATNQ--VEKAALVLDQNQDLRDKVDKLEASlkeanvskfssykvELLQQKLKllEERLQA 369
                         330       340       350
                  ....*....|....*....|....*....|....
gi 384946988  768 IRTENSSLTKEVQDLKAKQNDQVSfaSLVEELKK 801
Cdd:PLN02939  370 SDHEIHSYIQLYQESIKEFQDTLS--KLKEESKK 401
PTZ00121 PTZ00121
MAEBL; Provisional
744-1297 3.34e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 3.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  744 LKTVEELLETGLIQVATKEEELNAIRTENSSLTK---------------EVQDLKAKQNDQVSFASLVEELKKVIHE--K 806
Cdd:PTZ00121 1026 IEKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKaeakahvgqdeglkpSYKDFDFDAKEDNRADEATEEAFGKAEEakK 1105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  807 DGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNvQLEKAQQLSITSQVQELQNL-LKGKEEQMNTMKAVLEE 885
Cdd:PTZ00121 1106 TETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEAR-KAEDAKRVEIARKAEDARKAeEARKAEDAKKAEAARKA 1184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  886 KEKDLANTGKWLQDLQEENESLKAHVQEVAQhnlkEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQD 965
Cdd:PTZ00121 1185 EEVRKAEELRKAEDARKAEAARKAEEERKAE----EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  966 VQDENKLFKSQI---EQLKQQNYQQASSFPPHEELLKVISERE----KEISGLWNELDSLKDAVEHQRKKNNDLREKNWE 1038
Cdd:PTZ00121 1261 RMAHFARRQAAIkaeEARKADELKKAEEKKKADEAKKAEEKKKadeaKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEE 1340
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1039 AM---EALASTEKMLQDKVNKTSK----------ERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKEC 1105
Cdd:PTZ00121 1341 AKkaaEAAKAEAEAAADEAEAAEEkaeaaekkkeEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA 1420
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1106 MAGTSGSEEVKVLEHKLKEADEMHTllQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSS 1185
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKK--ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKK 1498
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1186 EQELERLRRENKDIENLRREREHLEM-ELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEE---------L 1255
Cdd:PTZ00121 1499 ADEAKKAAEAKKKADEAKKAEEAKKAdEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEakkaeedknM 1578
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 384946988 1256 NLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1297
Cdd:PTZ00121 1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI 1620
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1131-1345 3.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 3.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1131 LLQLECEKYKSVLAETEGILQKLQRSVEQEEnkwkvkvdeshKTIKQMQSSFTSSEQELERLRRE----NKDIENLRRER 1206
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELE-----------KELAALKKEEKALLKQLAALERRiaalARRIRALEQEL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1207 EHLEMELEKAEMERSTYVTEVRELKDLLTELQKKL--------------DDSYSEAVRQNEELNLLKAQLNETLTKLRTE 1272
Cdd:COG4942    79 AALEAELAELEKEIAELRAELEAQKEELAELLRALyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 384946988 1273 QNERQKVAGDLHKAQQSLELIQSKIVKAAGDItviensdvspETESSEKETMSVSLNQTVTQLQQLLQAVNQQ 1345
Cdd:COG4942   159 LAELAALRAELEAERAELEALLAELEEERAAL----------EALKAERQKLLARLEKELAELAAELAELQQE 221
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
570-948 3.92e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 3.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   570 QVQDILEQNEALKAQIQQFHSQI-AAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLK 648
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIeNRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   649 AEVQKLQALANEQAAAAHELEKMQQSVYVKDDkirlleeqlqheisnkMEEFKILNDQNKALKLEVQKLQTLVSEQPNKD 728
Cdd:TIGR02169  758 SELKELEARIEELEEDLHKLEEALNDLEARLS----------------HSRIPEIQAELSKLEEEVSRIEARLREIEQKL 821
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   729 VVEQMEKCIQEKdeKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDG 808
Cdd:TIGR02169  822 NRLTLEKEYLEK--EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD---LESRLGDLKKERDELEA 896
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   809 KIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQV---QELQNLLKGKEEQMNTMKAV--- 882
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVnml 976
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   883 ----LEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ--------------HNLKEV------SSASQFEE-------- 930
Cdd:TIGR02169  977 aiqeYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKkkrevfmeafeainENFNEIfaelsgGTGELILEnpddpfag 1056
                          410
                   ....*....|....*....
gi 384946988   931 -LEIVLKEKENELKRVEAM 948
Cdd:TIGR02169 1057 gLELSAKPKGKPVQRLEAM 1075
PRK11281 PRK11281
mechanosensitive channel MscK;
830-1078 4.33e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 4.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  830 TVQDLKQEIKALKEEignvQLEKAQQLSITSQVQELQNLLKGKEEQmntmKAVLEEKEKDLANTGKWLQDLQEENESLKA 909
Cdd:PRK11281   37 TEADVQAQLDALNKQ----KLLEAEDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALKD 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  910 HVQEVAQHNLKEVSSAsqfeELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQdeNKLFKSQiEQLKQQNYQQAS 989
Cdd:PRK11281  109 DNDEETRETLSTLSLR----QLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQ--AALYANS-QRLQQIRNLLKG 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  990 SFPPHEELlkviseREKEISGLWNELDSLKDAVEHQRK--KNND-----LREKNWEAMEALASTEKM---LQDKVN---- 1055
Cdd:PRK11281  182 GKVGGKAL------RPSQRVLLQAEQALLNAQNDLQRKslEGNTqlqdlLQKQRDYLTARIQRLEHQlqlLQEAINskrl 255
                         250       260
                  ....*....|....*....|....*..
gi 384946988 1056 ----KTSKERQQQVEAVELEAKEVLKK 1078
Cdd:PRK11281  256 tlseKTVQEAQSQDEAARIQANPLVAQ 282
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
431-641 4.54e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 4.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  431 DAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRtae 510
Cdd:COG3883    16 PQIQAKQKELSELQ-AELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER--- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  511 heAAQQDLQSKFVAKENEVqsLHSKLTDTLVSKQQLeqrLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQfhs 590
Cdd:COG3883    92 --ARALYRSGGSVSYLDVL--LGSESFSDFLDRLSA---LSKIADADADLLEELKADKAELEAKKAELEAKLAELEA--- 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 384946988  591 qiaAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQ 641
Cdd:COG3883   162 ---LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
829-1308 4.76e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 4.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  829 KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Cdd:PRK02224  206 ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLR 285
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  909 AHVQEVAQHNlKEVSSASQFEELEIvlkekenelKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQqa 988
Cdd:PRK02224  286 ERLEELEEER-DDLLAEAGLDDADA---------EAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADD-- 353
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  989 ssfppHEELLKVISEREKEisgLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLqDKVNKTSKERQQQVEAV 1068
Cdd:PRK02224  354 -----LEERAEELREEAAE---LESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDL-GNAEDFLEELREERDEL 424
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1069 ELEAKEVLKKLfpkVSVPSNLSYSEWLHGfEKKAKECMAGTSGSEEVKVLEHKLKEADEmhtlLQLECEKYKSVLAETEG 1148
Cdd:PRK02224  425 REREAELEATL---RTARERVEEAEALLE-AGKCPECGQPVEGSPHVETIEEDRERVEE----LEAELEDLEEEVEEVEE 496
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1149 ILQKLQRSVEQEE--NKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRRERE------HLEMELEKAEM-- 1218
Cdd:PRK02224  497 RLERAEDLVEAEDriERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKReaaaeaEEEAEEAREEVae 576
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1219 --ERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGD-----LHKAQQSLE 1291
Cdd:PRK02224  577 lnSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEfdearIEEAREDKE 656
                         490
                  ....*....|....*..
gi 384946988 1292 LIQSKIVKAAGDITVIE 1308
Cdd:PRK02224  657 RAEEYLEQVEEKLDELR 673
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
409-790 5.14e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 5.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  409 QQVREQMEAEIAHLKQENGILRDAVSNTTNQLEskqsaeLNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKV 488
Cdd:COG4717    94 QEELEELEEELEELEAELEELREELEKLEKLLQ------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEE 167
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  489 QLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLmESEQKRVNKEESLQ 568
Cdd:COG4717   168 LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL-ENELEAAALEERLK 246
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  569 MQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLAN-ERDHLTSKEEELKDIQNMNFLL 647
Cdd:COG4717   247 EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEaEELQALPALEELEEEELEELLA 326
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN------------------KMEEFKILNDQNKA 709
Cdd:COG4717   327 ALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllaeagvedeeelraaleQAEEYQELKEELEE 406
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  710 LKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN--SSLTKEVQDLKAKQN 787
Cdd:COG4717   407 LEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGelAELLQELEELKAELR 486

                  ...
gi 384946988  788 DQV 790
Cdd:COG4717   487 ELA 489
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
1183-1272 5.45e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 5.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1183 TSSEQELERLRREnkdIENLRREREHLEMELEKAEMER-STYVTEVRELKDLLTELQKK-----------------LDDS 1244
Cdd:COG0542   407 DSKPEELDELERR---LEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEALKARweaekelieeiqelkeeLEQR 483
                          90       100
                  ....*....|....*....|....*...
gi 384946988 1245 YSEAVRQNEELNLLKAQLNETLTKLRTE 1272
Cdd:COG0542   484 YGKIPELEKELAELEEELAELAPLLREE 511
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
934-1291 5.74e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.18  E-value: 5.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  934 VLKEKENELKRVEAMLKERESD-----LSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI 1008
Cdd:PRK02224  181 VLSDQRGSLDQLKAQIEEKEEKdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEI 260
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1009 SGL-------WNELDSLKDAVEHQRKKNNDLREknwEAMEALASTEkmLQDKVNKTSKERQQQVEAVELEAKEVLKKLFP 1081
Cdd:PRK02224  261 EDLretiaetEREREELAEEVRDLRERLEELEE---ERDDLLAEAG--LDDADAEAVEARREELEDRDEELRDRLEECRV 335
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1082 KVSVPSNL--SYSEWLHGFEKKAKECmagtsgSEEVKVLEHKLKEADEmhtllqlECEKYKSVLAETEGILQKLQ----- 1154
Cdd:PRK02224  336 AAQAHNEEaeSLREDADDLEERAEEL------REEAAELESELEEARE-------AVEDRREEIEELEEEIEELRerfgd 402
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1155 ----------RSVEQEENKwkvkvDESHKTIKQMQSSFTSSE---QELERLRRENK---------------DIENLRRER 1206
Cdd:PRK02224  403 apvdlgnaedFLEELREER-----DELREREAELEATLRTARervEEAEALLEAGKcpecgqpvegsphveTIEEDRERV 477
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1207 EHLEMELEKAEMERSTYVTEVRELKDLltelqkklddsySEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKA 1286
Cdd:PRK02224  478 EELEAELEDLEEEVEEVEERLERAEDL------------VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRER 545

                  ....*
gi 384946988 1287 QQSLE 1291
Cdd:PRK02224  546 AAELE 550
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
556-1344 5.88e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.19  E-value: 5.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   556 SEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEE 635
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   636 ELKDIQNmnfllkaevqklqalaneqaaAAHELEKMQQSVYVKDDKIRLLEEQlqheisnkmeefkilndqnkalKLEVQ 715
Cdd:TIGR00606  246 ELDPLKN---------------------RLKEIEHNLSKIMKLDNEIKALKSR----------------------KKQME 282
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   716 KLqtlvseqpNKDVVEQMEKCIQEKDEKLKTVEELLETgliQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASL 795
Cdd:TIGR00606  283 KD--------NSELELKMEKVFQGTDEQLNDLYHNHQR---TVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGR 351
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   796 VEELKKVIHEK-----------------DGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
Cdd:TIGR00606  352 LQLQADRHQEHirardsliqslatrlelDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEI 431
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   859 TSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQhnLKEVSSASQFEELEIVLKEK 938
Cdd:TIGR00606  432 RDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSK--AEKNSLTETLKKEVKSLQNE 509
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   939 ENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQ-------QASSFPPHEELLKVISEREKEISGL 1011
Cdd:TIGR00606  510 KADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRhsdeltsLLGYFPNKKQLEDWLHSKSKEINQT 589
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1012 WNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVnkTSKERQQQVEAVELEAKEVLKKLFPkVSVPSNLsY 1091
Cdd:TIGR00606  590 RDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVC--GSQDEESDLERLKEEIEKSSKQRAM-LAGATAV-Y 665
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1092 SEWLHGFEKKAKECMAGTSGSEEVKvlehklKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDES 1171
Cdd:TIGR00606  666 SQFITQLTDENQSCCPVCQRVFQTE------AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1172 HKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEmERSTYVTEVRELKDLLTELQKKLDDSYSEAvrQ 1251
Cdd:TIGR00606  740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAK-VCLTDVTIMERFQMELKDVERKIAQQAAKL--Q 816
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1252 NEELNLLKAQLNEtltKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQT 1331
Cdd:TIGR00606  817 GSDLDRTVQQVNQ---EKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVEL 893
                          810
                   ....*....|...
gi 384946988  1332 VTQLQQLLQAVNQ 1344
Cdd:TIGR00606  894 STEVQSLIREIKD 906
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
974-1291 6.11e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 40.88  E-value: 6.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   974 KSQIEQLKQQNYQQASSFppheellkviserEKEISGLWNELDSLKDAVEHQRKKNNDL-------REKNWEAMEALAST 1046
Cdd:pfam05557    8 KARLSQLQNEKKQMELEH-------------KRARIELEKKASALKRQLDRESDRNQELqkrirllEKREAEAEEALREQ 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1047 EKMLQ--DKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSvpsnlsysEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKE 1124
Cdd:pfam05557   75 AELNRlkKKYLEALNKKLNEKESQLADAREVISCLKNELS--------ELRRQIQRAELELQSTNSELEELQERLDLLKA 146
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1125 ADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENkWKVKVdeshKTIKQMQSSFTSSEQELERLRRENK------- 1197
Cdd:pfam05557  147 KASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQ-DSEIV----KNSKSELARIPELEKELERLREHNKhlnenie 221
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1198 DIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQ--KKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNE 1275
Cdd:pfam05557  222 NKLLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQswVKLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSS 301
                          330
                   ....*....|....*.
gi 384946988  1276 RQKVAGDLHKAQQSLE 1291
Cdd:pfam05557  302 LTSSARQLEKARRELE 317
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
479-594 6.67e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 40.42  E-value: 6.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  479 AEQAVTQLKVQLQEAERRWEEVQSYI--RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES 556
Cdd:COG1566    81 LQAALAQAEAQLAAAEAQLARLEAELgaEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAA 160
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 384946988  557 EQKRVNKEESLQMQVQDILEQNE--ALKAQIQQFHSQIAA 594
Cdd:COG1566   161 QAQLEAAQAQLAQAQAGLREEEElaAAQAQVAQAEAALAQ 200
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
1062-1296 6.74e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 6.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1062 QQQVEAVElEAKEVLKKlfPKVSvPSNLSysEWLHGFEKKAKEcmagtsGSEEVKVLEHKLKEADEMHTllqleceKYKS 1141
Cdd:COG3096   416 QQAVQALE-KARALCGL--PDLT-PENAE--DYLAAFRAKEQQ------ATEEVLELEQKLSVADAARR-------QFEK 476
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1142 VLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRRE-----------REHLE 1210
Cdd:COG3096   477 AYELVCKIAGEVERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEfcqrigqqldaAEELE 556
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1211 MELEKAEMERSTYVTEVRELKDLLTELQKKLDD---SYSEAVRQ-------NEELNLLKAQLNETLTKLRTEQNERQKVA 1280
Cdd:COG3096   557 ELLAELEAQLEELEEQAAEAVEQRSELRQQLEQlraRIKELAARapawlaaQDALERLREQSGEALADSQEVTAAMQQLL 636
                         250
                  ....*....|....*.
gi 384946988 1281 GDLHKAQQSLELIQSK 1296
Cdd:COG3096   637 EREREATVERDELAAR 652
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
625-1292 7.61e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 40.98  E-value: 7.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   625 NERDHLTSKEEELKDIQNMNFLLKAE-----VQKLQALANEQAAAAHELEKMQQSVYVKDD----KIRLLEEQLQHEISN 695
Cdd:pfam12128  150 NDRTLLGRERVELRSLARQFALCDSEsplrhIDKIAKAMHSKEGKFRDVKSMIVAILEDDGvvppKSRLNRQQVEHWIRD 229
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   696 KMEEFKILNDQNKALKLEVQ---------KLQTLVSEQpnKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELN 766
Cdd:pfam12128  230 IQAIAGIMKIRPEFTKLQQEfntlesaelRLSHLHFGY--KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELN 307
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   767 A-IRTENSSLTK------------------EVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEaellkvANK 827
Cdd:pfam12128  308 GeLSAADAAVAKdrselealedqhgafldaDIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYN------RRR 381
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   828 EKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQV-QELQNLLKgkeEQMNTMKAVLEEKEKDLANTGKWLQDL------ 900
Cdd:pfam12128  382 SKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDlQALESELR---EQLEAGKLEFNEEEYRLKSRLGELKLRlnqata 458
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   901 -------QEENESLKAHVQEVAQHNLKEVSSAsQFEEL----------------EIVLKEKENELKRVEAML-------- 949
Cdd:pfam12128  459 tpelllqLENFDERIERAREEQEAANAEVERL-QSELRqarkrrdqasealrqaSRRLEERQSALDELELQLfpqagtll 537
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   950 ----------KERESDLSSKTKLLQ----------DVQDENKLF--KSQIEQLkqqnyqQASSFPPHEELLK-------- 999
Cdd:pfam12128  538 hflrkeapdwEQSIGKVISPELLHRtdldpevwdgSVGGELNLYgvKLDLKRI------DVPEWAASEEELRerldkaee 611
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1000 -------VISEREKEISGLWNELDSLKDAVEHQRK--KNNDLREKNWeamealASTEKMLQDKVNKTSKERQQQVE---- 1066
Cdd:pfam12128  612 alqsareKQAAAEEQLVQANGELEKASREETFARTalKNARLDLRRL------FDEKQSEKDKKNKALAERKDSANerln 685
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1067 AVELEAKEVLKKLfpkvsvpsnlsySEWLHGFEKKAKEcmAGTSGSEEVKVLEHKLKeaDEMHTLLQLECEKYKSVLAET 1146
Cdd:pfam12128  686 SLEAQLKQLDKKH------------QAWLEEQKEQKRE--ARTEKQAYWQVVEGALD--AQLALLKAAIAARRSGAKAEL 749
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  1147 EGILQKLQRSVEqeenkwKVKVDEshKTIKQMQSSFTSSEQELERLRRENKDIENLRR-EREHLEMELEKAEMERSTYVT 1225
Cdd:pfam12128  750 KALETWYKRDLA------SLGVDP--DVIAKLKREIRTLERKIERIAVRRQEVLRYFDwYQETWLQRRPRLATQLSNIER 821
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 384946988  1226 EVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLEL 1292
Cdd:pfam12128  822 AISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSI 888
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
269-526 7.99e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 40.87  E-value: 7.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   269 KKLKTETDKENA-----EVKFKDFLLSLKTMMFSEDEAL-CVVDLLKEKSGVIQDAlkKSSKGELTTLVHQLQEKDKLLA 342
Cdd:pfam15921  607 QEFKILKDKKDAkirelEARVSDLELEKVKLVNAGSERLrAVKDIKQERDQLLNEV--KTSRNELNSLSEDYEVLKRNFR 684
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   343 AVKEDAAATKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMeaeiAHL 422
Cdd:pfam15921  685 NKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM----TNA 760
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988   423 KQENGILRDavsnttnqleskqsaELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQS 502
Cdd:pfam15921  761 NKEKHFLKE---------------EKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
                          250       260
                   ....*....|....*....|....
gi 384946988   503 YIRKRtaEHEAAQQDLQSKFVAKE 526
Cdd:pfam15921  826 IIQRQ--EQESVRLKLQHTLDVKE 847
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
554-859 8.40e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.61  E-value: 8.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  554 MESEQKR-VNKEESLQMQVQDILEQNEALKAQIQQfHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTS 632
Cdd:PLN03229  413 VDPERKVnMKKREAVKTPVRELEGEVEKLKEQILK-AKESSSKPSELALNEMIEKLKKEIDLEYTEAVIAMGLQERLENL 491
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  633 KEEELK---DIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR---LLE-----EQLQHEISNKMEEFK 701
Cdd:PLN03229  492 REEFSKansQDQLMHPVLMEKIEKLKDEFNKRLSRAPNYLSLKYKLDMLNEFSRakaLSEkkskaEKLKAEINKKFKEVM 571
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  702 I---LNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELnAIRTENSSLTKE 778
Cdd:PLN03229  572 DrpeIKEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDT-AEQTPPPNLQEK 650
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  779 VQDLKAKQNDQVSFASLVEELKKVIHEkdgkiKSVEELLEAELLKVANKEKtVQDLKQEIK----------ALKEEIGNV 848
Cdd:PLN03229  651 IESLNEEINKKIERVIRSSDLKSKIEL-----LKLEVAKASKTPDVTEKEK-IEALEQQIKqkiaealnssELKEKFEEL 724
                         330
                  ....*....|.
gi 384946988  849 QLEKAQQLSIT 859
Cdd:PLN03229  725 EAELAAARETA 735
PRK01156 PRK01156
chromosome segregation protein; Provisional
853-1243 8.42e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 40.66  E-value: 8.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  853 AQQLSITSQVQELQNLlkgkEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELE 932
Cdd:PRK01156  149 AQRKKILDEILEINSL----ERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLS 224
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988  933 IVLKEKENELKRVEAMLKERESDLSSKTKLLQDVqdenKLFKSQIEQLKQQNYQQASSFPPHEELL--KVISEREkEISG 1010
Cdd:PRK01156  225 IEYNNAMDDYNNLKSALNELSSLEDMKNRYESEI----KTAESDLSMELEKNNYYKELEERHMKIIndPVYKNRN-YIND 299
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1011 LWNELDSLKDAVEHQRKKNNDLrEKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFpkvsVPSNLS 1090
Cdd:PRK01156  300 YFKYKNDIENKKQILSNIDAEI-NKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSY----LKSIES 374
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1091 YSEWLHGFEKKAKECMAGTSGSEEVKVL--EHKLKEADEMHTLLQLECEKYKSVLAETEGILQK---LQRSVEQEENKWK 1165
Cdd:PRK01156  375 LKKKIEEYSKNIERMSAFISEILKIQEIdpDAIKKELNEINVKLQDISSKVSSLNQRIRALRENldeLSRNMEMLNGQSV 454
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384946988 1166 VKV-------DESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEMERstYVTEVRELKDLLTELQ 1238
Cdd:PRK01156  455 CPVcgttlgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINK--SINEYNKIESARADLE 532

                  ....*
gi 384946988 1239 KKLDD 1243
Cdd:PRK01156  533 DIKIK 537
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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