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Conserved domains on  [gi|383418275|gb|AFH32351|]
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kinectin isoform c [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
468-1240 1.65e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 1.65e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   468 KLQQEEVQKK--NAEQAVTQLKVQLQEAERRW-------EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTD 538
Cdd:TIGR02168  171 KERRKETERKleRTRENLDRLEDILNELERQLkslerqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   539 tLVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQFHSQIAAQtsaSVLAEELHKVIAEKDKQIK 617
Cdd:TIGR02168  251 -AEEELEELTAELQELEEKLEELRLEvSELEEEIEELQKELYALANEISRLEQQKQIL---RERLANLERQLEELEAQLE 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   618 QTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM 697
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   698 EEFKILNDQNKALKLEVQKLQTLVSEQPNKDV---VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE------------KTVQDLKQEIKALK 842
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEaalggrlqavvvENLNAAKKAIAFLK 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   843 E-EIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWL------QDLQEENESLKAHVQEVA 915
Cdd:TIGR02168  567 QnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRPGYR 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   916 QHNL------KEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS 989
Cdd:TIGR02168  647 IVTLdgdlvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   990 SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNL--SYSEWLH 1067
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkALREALD 806
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1068 GFEKKAKecmagtsgseEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIK 1147
Cdd:TIGR02168  807 ELRAELT----------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1148 QMQSSFTSSEQELERLRRE----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQN------ 1217
Cdd:TIGR02168  877 ALLNERASLEEALALLRSEleelSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSltleea 956
                          810       820
                   ....*....|....*....|....*
gi 383418275  1218 --ERQKVAGDLHKAQQSLELIQSKI 1240
Cdd:TIGR02168  957 eaLENKIEDDEEEARRRLKRLENKI 981
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
29-160 6.50e-12

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


:

Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 64.37  E-value: 6.50e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275    29 MKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKK------EIQNGNLHESD----SESVPRDFKLSDALAVEDdqVV 98
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTPTEKEKKKKEKKKEKKKkskkkeEKPNGKLPESEqadeSEEEPREFKTPDEAPSAA--LE 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275    99 PVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAA 160
Cdd:pfam05104   79 PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEEPPA 140
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
326-584 7.24e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 7.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  326 ELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERsnvvIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQ 405
Cdd:COG1196   268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER----RRELEERLEELEEELAELEEELEELEEELEELE 343
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  406 MKFQQVREQMEAEIAHLKQENGILRDAVsnttnQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQ 485
Cdd:COG1196   344 EELEEAEEELEEAEAELAEAEEALLEAE-----AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  486 LKVQLQEAERRWEEVqsyiRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Cdd:COG1196   419 LEEELEELEEALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
                         250
                  ....*....|....*....
gi 383418275  566 SLQMQVQDILEQNEALKAQ 584
Cdd:COG1196   495 LLLEAEADYEGFLEGVKAA 513
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
468-1240 1.65e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 1.65e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   468 KLQQEEVQKK--NAEQAVTQLKVQLQEAERRW-------EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTD 538
Cdd:TIGR02168  171 KERRKETERKleRTRENLDRLEDILNELERQLkslerqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   539 tLVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQFHSQIAAQtsaSVLAEELHKVIAEKDKQIK 617
Cdd:TIGR02168  251 -AEEELEELTAELQELEEKLEELRLEvSELEEEIEELQKELYALANEISRLEQQKQIL---RERLANLERQLEELEAQLE 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   618 QTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM 697
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   698 EEFKILNDQNKALKLEVQKLQTLVSEQPNKDV---VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE------------KTVQDLKQEIKALK 842
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEaalggrlqavvvENLNAAKKAIAFLK 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   843 E-EIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWL------QDLQEENESLKAHVQEVA 915
Cdd:TIGR02168  567 QnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRPGYR 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   916 QHNL------KEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS 989
Cdd:TIGR02168  647 IVTLdgdlvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   990 SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNL--SYSEWLH 1067
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkALREALD 806
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1068 GFEKKAKecmagtsgseEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIK 1147
Cdd:TIGR02168  807 ELRAELT----------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1148 QMQSSFTSSEQELERLRRE----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQN------ 1217
Cdd:TIGR02168  877 ALLNERASLEEALALLRSEleelSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSltleea 956
                          810       820
                   ....*....|....*....|....*
gi 383418275  1218 --ERQKVAGDLHKAQQSLELIQSKI 1240
Cdd:TIGR02168  957 eaLENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-983 2.97e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 2.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  446 AELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEEL 605
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  606 HKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLL 685
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  686 EEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEkLKTVEELLETgLIQVATKEEEL 765
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV-LIGVEAAYEA-ALEAALAAALQ 549
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV---------EELLEAELLKVANKEKTVQDLKQ 836
Cdd:COG1196   550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIgaavdlvasDLREADARYYVLGDTLLGRTLVA 629
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  837 EIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ 916
Cdd:COG1196   630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 383418275  917 HNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLfKSQIEQLKQQ 983
Cdd:COG1196   710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-ERELERLERE 775
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
29-160 6.50e-12

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 64.37  E-value: 6.50e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275    29 MKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKK------EIQNGNLHESD----SESVPRDFKLSDALAVEDdqVV 98
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTPTEKEKKKKEKKKEKKKkskkkeEKPNGKLPESEqadeSEEEPREFKTPDEAPSAA--LE 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275    99 PVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAA 160
Cdd:pfam05104   79 PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEEPPA 140
PTZ00121 PTZ00121
MAEBL; Provisional
452-1147 1.39e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 1.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  452 RQDYARLVNELTEKTGKLQQEEVQKknAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS 531
Cdd:PTZ00121 1165 KAEEARKAEDAKKAEAARKAEEVRK--AEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEA 1242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  532 LHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESlqMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEElhkviAE 611
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE-----AK 1315
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  612 KDKQIKQTEDSLANERDHLTSKEEELKDIQNMNfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA-KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  692 EISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEK---DEKLKTVEElletgliqvATKEEELNAI 768
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkaDEAKKKAEE---------AKKAEEAKKK 1465
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  769 RTEnsslTKEVQDLKAKQNDqvsfASLVEELKKVIHEkdGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEignv 848
Cdd:PTZ00121 1466 AEE----AKKADEAKKKAEE----AKKADEAKKKAEE--AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE---- 1531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  849 QLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE----VSS 924
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEkkmkAEE 1611
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  925 ASQFEELEIVLKE--KENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAssfpphEELLKVIS 1002
Cdd:PTZ00121 1612 AKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA------EEAKKAEE 1685
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1003 EREKEISGLWNELDSlKDAVEHQRKKNNERQQQVEAVELEAKevlkklfpkvsvpsnlsysewlhgfEKKAKECMAGTSG 1082
Cdd:PTZ00121 1686 DEKKAAEALKKEAEE-AKKAEELKKKEAEEKKKAEELKKAEE-------------------------ENKIKAEEAKKEA 1739
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 383418275 1083 SEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIK 1147
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIF 1804
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
376-983 4.35e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 4.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   376 MKDRIGTLEKEHnvfQNKIHVSYQetqQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKlRQDY 455
Cdd:pfam15921  243 VEDQLEALKSES---QNKIELLLQ---QHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ-NSMY 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   456 ARLVNELtektgklqqeevqkknaEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Cdd:pfam15921  316 MRQLSDL-----------------ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQ 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   536 LTDTLVSKQQLEQRLMQLMESEQKRVNKE--------------ESLQMQVQDILEQNEALKAQIQ-QFHSQIAAQTSASV 600
Cdd:pfam15921  379 LQKLLADLHKREKELSLEKEQNKRLWDRDtgnsitidhlrrelDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNE 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   601 LAEELHKVIAekdkQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEvqkLQALANEQAAAAHELEKMQQSVYVKdd 680
Cdd:pfam15921  459 SLEKVSSLTA----QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS---LQEKERAIEATNAEITKLRSRVDLK-- 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   681 kirllEEQLQHeISNKMEEFKILNDQNKALKLEvqklqtlvseqpnkdvveqmekcIQEKDEKLKTVEELLETGLIQVAT 760
Cdd:pfam15921  530 -----LQELQH-LKNEGDHLRNVQTECEALKLQ-----------------------MAEKDKVIEILRQQIENMTQLVGQ 580
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   761 KEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKA 840
Cdd:pfam15921  581 HGRTAGAMQVEKAQLEKEINDRRLELQE---FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQ 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   841 LKEEIGNVQLEKAqqlSITSQVQELQNLLKGKEEQM----NTMKAVLEEKEKDLANTGKWLQDLqeenESLKAHVQEVAQ 916
Cdd:pfam15921  658 LLNEVKTSRNELN---SLSEDYEVLKRNFRNKSEEMetttNKLKMQLKSAQSELEQTRNTLKSM----EGSDGHAMKVAM 730
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 383418275   917 HNLKEVSSA-SQFEELEI---VLKEKENELKRVEAMLKERESDLSSKtklLQDVQDENKLFKSQIEQLKQQ 983
Cdd:pfam15921  731 GMQKQITAKrGQIDALQSkiqFLEEAMTNANKEKHFLKEEKNKLSQE---LSTVATEKNKMAGELEVLRSQ 798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
326-584 7.24e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 7.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  326 ELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERsnvvIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQ 405
Cdd:COG1196   268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER----RRELEERLEELEEELAELEEELEELEEELEELE 343
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  406 MKFQQVREQMEAEIAHLKQENGILRDAVsnttnQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQ 485
Cdd:COG1196   344 EELEEAEEELEEAEAELAEAEEALLEAE-----AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  486 LKVQLQEAERRWEEVqsyiRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Cdd:COG1196   419 LEEELEELEEALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
                         250
                  ....*....|....*....
gi 383418275  566 SLQMQVQDILEQNEALKAQ 584
Cdd:COG1196   495 LLLEAEADYEGFLEGVKAA 513
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
296-635 7.38e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 7.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   296 FSEDEALCVVDLLKEKSGVIQDALKKSSKgELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIAR 375
Cdd:pfam12128  597 ASEEELRERLDKAEEALQSAREKQAAAEE-QLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE 675
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   376 MKD----RIGTLEKEHNVFQNKIHVSYQETQ--------QMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESK 443
Cdd:pfam12128  676 RKDsaneRLNSLEAQLKQLDKKHQAWLEEQKeqkreartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW 755
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   444 QSAELNKLRQD---YARLVNELTEKTGKLQQEEVQkknaEQAVTQLKVQLQEaerRWEEVQSYIRKRTAEHEAAQQDLQS 520
Cdd:pfam12128  756 YKRDLASLGVDpdvIAKLKREIRTLERKIERIAVR----RQEVLRYFDWYQE---TWLQRRPRLATQLSNIERAISELQQ 828
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL---MESEQKRVNK------EESLQM-------QVQDILEQNEALKAQ 584
Cdd:pfam12128  829 QLARLIADTKLRRAKLEMERKASEKQQVRLSENlrgLRCEMSKLATlkedanSEQAQGsigerlaQLEDLKLKRDYLSES 908
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 383418275   585 IQQFHSQ---IAAQTSASVLAEELHKvIAEKDKQIKQTEDSLANERDHLTSKEE 635
Cdd:pfam12128  909 VKKYVEHfknVIADHSGSGLAETWES-LREEDHYQNDKGIRLLDYRKLVPYLEQ 961
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
412-621 5.42e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 5.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  412 REQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY-------ARLVN-ELTEKTGKLQQEEVQKKNAEQAV 483
Cdd:NF012221 1564 KERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQrdaileeSRAVTkELTTLAQGLDALDSQATYAGESG 1643
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  484 TQLKVQLqeAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKlTDTLVskQQLEQRLMQLMESEQKRVNK 563
Cdd:NF012221 1644 DQWRNPF--AGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAK-SEAGV--AQGEQNQANAEQDIDDAKAD 1718
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275  564 EESLQMQVqdILEQNEALKAQIQQFHS----QIAAQTSASVLAEELHKVIAEKdKQIKQTED 621
Cdd:NF012221 1719 AEKRKDDA--LAKQNEAQQAESDANAAandaQSRGEQDASAAENKANQAQADA-KGAKQDES 1777
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
468-1240 1.65e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 1.65e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   468 KLQQEEVQKK--NAEQAVTQLKVQLQEAERRW-------EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTD 538
Cdd:TIGR02168  171 KERRKETERKleRTRENLDRLEDILNELERQLkslerqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   539 tLVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQFHSQIAAQtsaSVLAEELHKVIAEKDKQIK 617
Cdd:TIGR02168  251 -AEEELEELTAELQELEEKLEELRLEvSELEEEIEELQKELYALANEISRLEQQKQIL---RERLANLERQLEELEAQLE 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   618 QTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM 697
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   698 EEFKILNDQNKALKLEVQKLQTLVSEQPNKDV---VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE------------KTVQDLKQEIKALK 842
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEaalggrlqavvvENLNAAKKAIAFLK 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   843 E-EIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWL------QDLQEENESLKAHVQEVA 915
Cdd:TIGR02168  567 QnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRPGYR 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   916 QHNL------KEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS 989
Cdd:TIGR02168  647 IVTLdgdlvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   990 SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNL--SYSEWLH 1067
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkALREALD 806
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1068 GFEKKAKecmagtsgseEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIK 1147
Cdd:TIGR02168  807 ELRAELT----------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1148 QMQSSFTSSEQELERLRRE----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQN------ 1217
Cdd:TIGR02168  877 ALLNERASLEEALALLRSEleelSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSltleea 956
                          810       820
                   ....*....|....*....|....*
gi 383418275  1218 --ERQKVAGDLHKAQQSLELIQSKI 1240
Cdd:TIGR02168  957 eaLENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
679-1300 4.57e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 4.57e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   679 DDKIRLLEEQLQH--EISNKMEEFKILNDQNKALKLEVQ--KLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Cdd:TIGR02168  192 EDILNELERQLKSleRQAEKAERYKELKAELRELELALLvlRLEELREElEELQEELKEAEEELEELTAELQELEEKLEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   754 GLIQVATKEEELNAIRTENSSLTKEVQDLKA-KQNDQVSFASLVEELKkvihEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQqKQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEEKLE 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   833 DLKQEIKALKEEIGNVQLEKAQQLS----ITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL- 907
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESrleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELl 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   908 --------KAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDL---SSKTKLLQDVQDENKLFKSQ 976
Cdd:TIGR02168  428 kkleeaelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlQARLDSLERLQENLEGFSEG 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   977 IEQLKQQNYQQASSFPPHEELLKVISEREKEISG---------LWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVL 1047
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAAIEAalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1048 -KKLFPKVSVPSNLSYSEWLHGFEKKAKECMAGTSG----SEEVKVLEHKLKEADEMHTLLQLECE----KYKSVLAETE 1118
Cdd:TIGR02168  588 gNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGgvlvVDDLDNALELAKKLRPGYRIVTLDGDlvrpGGVITGGSAK 667
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1119 GILQKLQRSVEQEENKwkvkvdeshKTIKQMQSSFTSSEQELERLRRENKDIEN----LRREREHLEMELEKAEMERSTY 1194
Cdd:TIGR02168  668 TNSSILERRREIEELE---------EKIEELEEKIAELEKALAELRKELEELEEeleqLRKELEELSRQISALRKDLARL 738
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1195 VTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQT 1274
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818
                          650       660
                   ....*....|....*....|....*.
gi 383418275  1275 VTQLQQLLQAVNQQLTKEKEHYQVLE 1300
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLE 844
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-983 2.97e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 2.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  446 AELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAK 525
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEEL 605
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  606 HKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLL 685
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  686 EEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEkLKTVEELLETgLIQVATKEEEL 765
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV-LIGVEAAYEA-ALEAALAAALQ 549
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV---------EELLEAELLKVANKEKTVQDLKQ 836
Cdd:COG1196   550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIgaavdlvasDLREADARYYVLGDTLLGRTLVA 629
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  837 EIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ 916
Cdd:COG1196   630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 383418275  917 HNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLfKSQIEQLKQQ 983
Cdd:COG1196   710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-ERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
398-951 4.87e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 4.87e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKK 477
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  478 NAEQAvtqlKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Cdd:COG1196   313 ELEER----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEEL 637
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  638 KDIQNmnfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQheISNKMEEFKILNDQNKALKLEVQKL 717
Cdd:COG1196   469 LEEAA---LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAA 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  718 QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMN 877
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 383418275  878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEI-VLKEKENELKRVEAMLKE 951
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
309-1023 3.22e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 3.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   309 KEKSGVIQDALKKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKER---SNVVIARMKDRIGTLEK 385
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEleeLEAELEELESRLEELEE 379
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   386 EHNVFQNKIHVSYQETQQMQMKFQqvreQMEAEIAHLKQENGILRdavSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIE----RLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEEL 452
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   466 TGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSyirkRTAEHEAAQQDLQSKFVAKENEVQSLhSKLTDTLvskqq 545
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQA----RLDSLERLQENLEGFSEGVKALLKNQ-SGLSGIL----- 522
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   546 leQRLMQLMESEQK-RVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA-SVLAEELHKVIAEKDKQIKQTEDSL 623
Cdd:TIGR02168  523 --GVLSELISVDEGyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTfLPLDSIKGTEIQGNDREILKNIEGF 600
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   624 ANERDHLTSKEEELKDiqNMNFLL-----------KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRK--ALSYLLggvlvvddldnALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRRE 678
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   693 ISNKMEEFKILNDQNKALKLEVQKLQTLVSEQpnKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN 772
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEEL--EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   773 SSLTKEVQDLKAKqndqvsfaslVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK 852
Cdd:TIGR02168  757 TELEAEIEELEER----------LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   853 AQQL----SITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLAntgkwlqdlqEENESLKAHVQEVAQHNLKEVSSASQF 928
Cdd:TIGR02168  827 ESLErriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIE----------ELESELEALLNERASLEEALALLRSEL 896
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   929 EELEIVLKEKENELKRVEAMLKEResdlssKTKLLQDVQDENKLfKSQIEQLKQQNYQQASSfpPHEELLKVISEREKEI 1008
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEEL------REKLAQLELRLEGL-EVRIDNLQERLSEEYSL--TLEEAEALENKIEDDE 967
                          730
                   ....*....|....*
gi 383418275  1009 SGLWNELDSLKDAVE 1023
Cdd:TIGR02168  968 EEARRRLKRLENKIK 982
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
29-160 6.50e-12

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 64.37  E-value: 6.50e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275    29 MKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKK------EIQNGNLHESD----SESVPRDFKLSDALAVEDdqVV 98
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTPTEKEKKKKEKKKEKKKkskkkeEKPNGKLPESEqadeSEEEPREFKTPDEAPSAA--LE 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275    99 PVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAA 160
Cdd:pfam05104   79 PEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEEPPA 140
PTZ00121 PTZ00121
MAEBL; Provisional
452-1147 1.39e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 1.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  452 RQDYARLVNELTEKTGKLQQEEVQKknAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS 531
Cdd:PTZ00121 1165 KAEEARKAEDAKKAEAARKAEEVRK--AEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEA 1242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  532 LHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESlqMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEElhkviAE 611
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE-----AK 1315
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  612 KDKQIKQTEDSLANERDHLTSKEEELKDIQNMNfLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA-KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  692 EISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEK---DEKLKTVEElletgliqvATKEEELNAI 768
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkaDEAKKKAEE---------AKKAEEAKKK 1465
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  769 RTEnsslTKEVQDLKAKQNDqvsfASLVEELKKVIHEkdGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEignv 848
Cdd:PTZ00121 1466 AEE----AKKADEAKKKAEE----AKKADEAKKKAEE--AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE---- 1531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  849 QLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE----VSS 924
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEkkmkAEE 1611
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  925 ASQFEELEIVLKE--KENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAssfpphEELLKVIS 1002
Cdd:PTZ00121 1612 AKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA------EEAKKAEE 1685
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1003 EREKEISGLWNELDSlKDAVEHQRKKNNERQQQVEAVELEAKevlkklfpkvsvpsnlsysewlhgfEKKAKECMAGTSG 1082
Cdd:PTZ00121 1686 DEKKAAEALKKEAEE-AKKAEELKKKEAEEKKKAEELKKAEE-------------------------ENKIKAEEAKKEA 1739
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 383418275 1083 SEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIK 1147
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIF 1804
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
757-1050 4.95e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 4.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  757 QVATKEEELNAIRTENSSLTKEVQDLKAKqndqvsfaslVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQ 836
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAE----------LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  837 EIKALKEEIGNVQLEKAQqlsITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ 916
Cdd:COG1196   310 RRRELEERLEELEEELAE---LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  917 HNLKEVSSASQFE-ELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQassfpphE 995
Cdd:COG1196   387 ELLEALRAAAELAaQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE-------E 459
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 383418275  996 ELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKL 1050
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
628-1237 2.56e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.00  E-value: 2.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  628 DHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND-Q 706
Cdd:PRK03918  158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElK 237
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  707 NKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETgLIQVATKEEELNAIRTENSSLTKEVQDLKAKQ 786
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRL 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  787 NDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQdLKQEIKALKEEIGNVQLEKAQqLSITSQVQELQ 866
Cdd:PRK03918  317 SRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHE-LYEEAKAKKEELERLKKRLTG-LTPEKLEKELE 394
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  867 NLLKGKEEQMNTMKAVLEEKeKDLANTGKWLQDLQEENESLKA------------HVQEVAQHNLKEVSS-ASQFEELEI 933
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARI-GELKKEIKELKKAIEELKKAKGkcpvcgrelteeHRKELLEEYTAELKRiEKELKEIEE 473
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  934 VLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQqassfppHEELLKVISEREKEISGLWN 1013
Cdd:PRK03918  474 KERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE-------YEKLKEKLIKLKGEIKSLKK 546
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1014 ELDSLKDAvehqRKKNNERQQQVEAVELEAKEVLKKLfpkvsvpsnlsysewlhgfekkakecmaGTSGSEEVKVLEHKL 1093
Cdd:PRK03918  547 ELEKLEEL----KKKLAELEKKLDELEEELAELLKEL----------------------------EELGFESVEELEERL 594
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1094 KEADEMHtllqlecEKYKSvLAETEGILQKLQRSVEQEENKwkvkVDESHKTIKQMQSSFTSSEQELERLRRE--NKDIE 1171
Cdd:PRK03918  595 KELEPFY-------NEYLE-LKDAEKELEREEKELKKLEEE----LDKAFEELAETEKRLEELRKELEELEKKysEEEYE 662
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 383418275 1172 NLRREREHLEMELEKAEMErstyVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQ 1237
Cdd:PRK03918  663 ELREEYLELSRELAGLRAE----LEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVE 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
667-1055 2.80e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 2.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   667 ELEKMQQSVYVKDDKIRLLEEQLQ--HEISNKMEEFKILNDqnkalKLEVQKLQTLVSEqpnkdvVEQMEKCIQEKDEKL 744
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLErlRREREKAERYQALLK-----EKREYEGYELLKE------KEALERQKEAIERQL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   745 KTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKakQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKV 824
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   825 ANKEKTVQDLKQEIKALKEEIGNVQLEKAQqlsitsqvqeLQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN 904
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDK----------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   905 ESLKahvQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQN 984
Cdd:TIGR02169  395 EKLK---REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 383418275   985 YQQASSfppheellkvISEREKEISGLWNELdslkDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVS 1055
Cdd:TIGR02169  472 YDLKEE----------YDRVEKELSKLQREL----AEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVA 528
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
463-1263 4.86e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 4.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   463 TEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEvqsyIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLtdtlvs 542
Cdd:TIGR02169  205 REREKAERYQALLKEKREYEGYELLKEKEALERQKEA----IERQLASLEEELEKLTEEISELEKRLEEIEQLL------ 274
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   543 kQQLEQRLMQLMESEQKRVNKE--------ESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAsvlAEELHKVIAEKDK 614
Cdd:TIGR02169  275 -EELNKKIKDLGEEEQLRVKEKigeleaeiASLERSIAEKERELEDAEERLAKLEAEIDKLLAE---IEELEREIEEERK 350
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   615 QIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS 694
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   695 NKMEEFKILNDQNKALKLEVQKLQTLVSEqpNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSS 774
Cdd:TIGR02169  431 GIEAKINELEEEKEDKALEIKKQEWKLEQ--LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG 508
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   775 lTKEVQDLKAKQNDQVsfASLVEELKKVIHEKDGKIKsVEELLEAELLKVANKEktvqDLKQEIKALKEEignvQLEKAQ 854
Cdd:TIGR02169  509 -GRAVEEVLKASIQGV--HGTVAQLGSVGERYATAIE-VAAGNRLNNVVVEDDA----VAKEAIELLKRR----KAGRAT 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   855 QLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKW-LQD--LQEENESLKAHVQEVAQHNL------------ 919
Cdd:TIGR02169  577 FLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvFGDtlVVEDIEAARRLMGKYRMVTLegelfeksgamt 656
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   920 --------KEVSSASQFEELEIV---LKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQnyqqa 988
Cdd:TIGR02169  657 ggsraprgGILFSRSEPAELQRLrerLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE----- 731
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   989 ssfppHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLfpkvsvpsnlsysewlhg 1068
Cdd:TIGR02169  732 -----EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL------------------ 788
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1069 fekkakecmagtsGSEEVKVLEHKLKEADEMHTllqleceKYKSVLAETEGILQKLQRSVEQEENKWKVKVDEshktikq 1148
Cdd:TIGR02169  789 -------------SHSRIPEIQAELSKLEEEVS-------RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ------- 841
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1149 mqssftssEQELERLRRENKD-IENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLH 1227
Cdd:TIGR02169  842 --------RIDLKEQIKSIEKeIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913
                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 383418275  1228 KAQQSLELIQSKIVKAAGDITVIENSDVSPETESSE 1263
Cdd:TIGR02169  914 KKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEE 949
PTZ00121 PTZ00121
MAEBL; Provisional
602-1272 6.80e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 6.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  602 AEELHKviAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNflLKAEVQKLQALANEQAAAAHELEKMQQSVYvKDDK 681
Cdd:PTZ00121 1142 AEEARK--AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAAR--KAEEVRKAEELRKAEDARKAEAARKAEEER-KAEE 1216
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  682 IRLLEEQLQHEISNKMEEFKilNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETgliqvatk 761
Cdd:PTZ00121 1217 ARKAEDAKKAEAVKKAEEAK--KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA-------- 1286
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  762 EEELNAIRTENSSLTKEVQDLKAKQNDqvsfASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKAL 841
Cdd:PTZ00121 1287 EEKKKADEAKKAEEKKKADEAKKKAEE----AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  842 KEEIGNVQLE------KAQQLSITSQVQELQNLLKGKEEQ----MNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV 911
Cdd:PTZ00121 1363 EEKAEAAEKKkeeakkKADAAKKKAEEKKKADEAKKKAEEdkkkADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  912 QEVAQHNLKEVSSASQFEELeivlKEKENELKRVEAMLKERESDLSS---KTKLLQDVQDENKLFKSQIEQLKQQNYQQA 988
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEA----KKKAEEAKKADEAKKKAEEAKKAdeaKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  989 SSFPPHEELLKVISER---------EKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSN 1059
Cdd:PTZ00121 1519 EEAKKADEAKKAEEAKkadeakkaeEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1060 LSYSEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVL-AETEGILQKLQRSVEQEENKWKVK 1138
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKkAEEENKIKAAEEAKKAEEDKKKAE 1678
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1139 vdeshkTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEM---ELEKAEMERSTYVTEVRELKAQLNETLTKLRTE 1215
Cdd:PTZ00121 1679 ------EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKkaeELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 383418275 1216 QNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLN 1272
Cdd:PTZ00121 1753 EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFAN 1809
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
309-1050 1.29e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 1.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   309 KEKSGVIQDALKKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLT---QEMMSEKERSNVVIARMKDRIGTL-E 384
Cdd:TIGR02169  207 REKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTeeiSELEKRLEEIEQLLEELNKKIKDLgE 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   385 KEHNVFQNKI---HVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNE 461
Cdd:TIGR02169  287 EEQLRVKEKIgelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER-KRRDKLTEEYAELKEE 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   462 LTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRK---RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTD 538
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKED 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   539 TLVSKQQLEQRLMQL---MESEQKRVNKEESLQMQVQDILEQNE----ALKAQIQQFHSQIAAQTSASVLAEE----LHK 607
Cdd:TIGR02169  446 KALEIKKQEWKLEQLaadLSKYEQELYDLKEEYDRVEKELSKLQrelaEAEAQARASEERVRGGRAVEEVLKAsiqgVHG 525
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   608 VIAE----KDKQIKQTEDSLANERDHLTSKEEE--------LKD--IQNMNFLLKAEVQKLQAlaneqaaaahELEKMQQ 673
Cdd:TIGR02169  526 TVAQlgsvGERYATAIEVAAGNRLNNVVVEDDAvakeaielLKRrkAGRATFLPLNKMRDERR----------DLSILSE 595
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   674 SVYVkDDKIRLLEEQLQHE-----------ISNKMEEFKILNDQNKALKLEVQKLQT-------LVSEQPNKDVVEQMEK 735
Cdd:TIGR02169  596 DGVI-GFAVDLVEFDPKYEpafkyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKsgamtggSRAPRGGILFSRSEPA 674
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   736 CIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQN----DQVSFASLVEELKKVIHEKDGKIK 811
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEqleqEEEKLKERLEELEEDLSSLEQEIE 754
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   812 SVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKaqqlsITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 891
Cdd:TIGR02169  755 NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPE-----IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   892 NTGKWLQDLQEENESLKAHVQEVAQhnlKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENK 971
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEK---EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE 906
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   972 LFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDaVEHQRKKNNERQQQVEAVELEA----KEVL 1047
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVNMLAiqeyEEVL 985

                   ...
gi 383418275  1048 KKL 1050
Cdd:TIGR02169  986 KRL 988
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
416-981 1.59e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 1.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  416 EAEIAHLKQENGILRDAVSNTTNQLESKQ---SAELNKLRqdyaRLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQE 492
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELpelREELEKLE----KEVKELEELKEEIEELEKELESLEGSKRKLEEKIRE 263
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  493 AERRWEEVqsyiRKRTAEHEAAQQDLQS-KFVAKE-NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQ 570
Cdd:PRK03918  264 LEERIEEL----KKEIEELEEKVKELKElKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEER 339
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  571 VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKViaeKDKQIKQTEDSLANERDHLTSKEEEL-KDIQNmnflLKA 649
Cdd:PRK03918  340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERL---KKRLTGLTPEKLEKELEELEKAKEEIeEEISK----ITA 412
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  650 EVQKLQALANEQAAAAHELEKMQQSVYV------KDDKIRLLEEQLQhEISNKMEEFKILNDQNKALKLEVQKLQTLVSE 723
Cdd:PRK03918  413 RIGELKKEIKELKKAIEELKKAKGKCPVcgreltEEHRKELLEEYTA-ELKRIEKELKEIEEKERKLRKELRELEKVLKK 491
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  724 QPNKDVVEQMEKCIQEKDEKLKTVE-ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAkqndqvsFASLVEELKKV 802
Cdd:PRK03918  492 ESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE-------LKKKLAELEKK 564
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  803 IHEKDGKIKSVEELLEAELLKvankekTVQDLKQEIKALkEEIGNVQLEkaqQLSITSQVQELQNLLKGKEEQmntmkav 882
Cdd:PRK03918  565 LDELEEELAELLKELEELGFE------SVEELEERLKEL-EPFYNEYLE---LKDAEKELEREEKELKKLEEE------- 627
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  883 LEEKEKDLANTGKWLQDLQEENESLKAHVQEvaqhnlkevssaSQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKL 962
Cdd:PRK03918  628 LDKAFEELAETEKRLEELRKELEELEKKYSE------------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKT 695
                         570
                  ....*....|....*....
gi 383418275  963 LQDVQDENKLFKSQIEQLK 981
Cdd:PRK03918  696 LEKLKEELEEREKAKKELE 714
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
324-988 2.85e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 2.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   324 KGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEK---EHNVFQNKIHVSYQE 400
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkrEINELKRELDRLQEE 414
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   401 TQQMQMKFQQVREQM---EAEIAHLKQENGILRDAVSNTTNQLES------KQSAELNKLRQDYARLVNELTEKTGKLQQ 471
Cdd:TIGR02169  415 LQRLSEELADLNAAIagiEAKINELEEEKEDKALEIKKQEWKLEQlaadlsKYEQELYDLKEEYDRVEKELSKLQRELAE 494
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   472 EEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRK--------RTAEHEAAQQDLQSKFVAKE----------------- 526
Cdd:TIGR02169  495 AEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQlgsvgeryATAIEVAAGNRLNNVVVEDDavakeaiellkrrkagr 574
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   527 ------NEVQSLHSKLTdtLVSKQQLEQRLMQLMESEQKRvnkEESLQMQVQD--ILEQNEALKAQIQQFH--------- 589
Cdd:TIGR02169  575 atflplNKMRDERRDLS--ILSEDGVIGFAVDLVEFDPKY---EPAFKYVFGDtlVVEDIEAARRLMGKYRmvtlegelf 649
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   590 SQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELE 669
Cdd:TIGR02169  650 EKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE 729
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   670 KMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQmekcIQEKDEKLKTVEE 749
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR----IPEIQAELSKLEE 805
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   750 LLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829
Cdd:TIGR02169  806 EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRID---LKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   830 TVQDLKQEIKALKEEIGNVQlekaqqlsitSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKa 909
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELE----------RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL- 951
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 383418275   910 hVQEVAQHNLKEVSSAsqFEELEIVLKEKENELKRVEAmlkeRESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQA 988
Cdd:TIGR02169  952 -SLEDVQAELQRVEEE--IRALEPVNMLAIQEYEEVLK----RLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
376-983 4.35e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 4.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   376 MKDRIGTLEKEHnvfQNKIHVSYQetqQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKlRQDY 455
Cdd:pfam15921  243 VEDQLEALKSES---QNKIELLLQ---QHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ-NSMY 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   456 ARLVNELtektgklqqeevqkknaEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Cdd:pfam15921  316 MRQLSDL-----------------ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQ 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   536 LTDTLVSKQQLEQRLMQLMESEQKRVNKE--------------ESLQMQVQDILEQNEALKAQIQ-QFHSQIAAQTSASV 600
Cdd:pfam15921  379 LQKLLADLHKREKELSLEKEQNKRLWDRDtgnsitidhlrrelDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNE 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   601 LAEELHKVIAekdkQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEvqkLQALANEQAAAAHELEKMQQSVYVKdd 680
Cdd:pfam15921  459 SLEKVSSLTA----QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS---LQEKERAIEATNAEITKLRSRVDLK-- 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   681 kirllEEQLQHeISNKMEEFKILNDQNKALKLEvqklqtlvseqpnkdvveqmekcIQEKDEKLKTVEELLETGLIQVAT 760
Cdd:pfam15921  530 -----LQELQH-LKNEGDHLRNVQTECEALKLQ-----------------------MAEKDKVIEILRQQIENMTQLVGQ 580
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   761 KEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKA 840
Cdd:pfam15921  581 HGRTAGAMQVEKAQLEKEINDRRLELQE---FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQ 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   841 LKEEIGNVQLEKAqqlSITSQVQELQNLLKGKEEQM----NTMKAVLEEKEKDLANTGKWLQDLqeenESLKAHVQEVAQ 916
Cdd:pfam15921  658 LLNEVKTSRNELN---SLSEDYEVLKRNFRNKSEEMetttNKLKMQLKSAQSELEQTRNTLKSM----EGSDGHAMKVAM 730
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 383418275   917 HNLKEVSSA-SQFEELEI---VLKEKENELKRVEAMLKERESDLSSKtklLQDVQDENKLFKSQIEQLKQQ 983
Cdd:pfam15921  731 GMQKQITAKrGQIDALQSkiqFLEEAMTNANKEKHFLKEEKNKLSQE---LSTVATEKNKMAGELEVLRSQ 798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
326-584 7.24e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 7.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  326 ELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERsnvvIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQ 405
Cdd:COG1196   268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER----RRELEERLEELEEELAELEEELEELEEELEELE 343
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  406 MKFQQVREQMEAEIAHLKQENGILRDAVsnttnQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQ 485
Cdd:COG1196   344 EELEEAEEELEEAEAELAEAEEALLEAE-----AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  486 LKVQLQEAERRWEEVqsyiRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Cdd:COG1196   419 LEEELEELEEALAEL----EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
                         250
                  ....*....|....*....
gi 383418275  566 SLQMQVQDILEQNEALKAQ 584
Cdd:COG1196   495 LLLEAEADYEGFLEGVKAA 513
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
376-806 8.09e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 8.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   376 MKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDaVSNTTNQLESKQSAELNKLRQDY 455
Cdd:TIGR04523  230 LKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE-LEKQLNQLKSEISDLNNQKEQDW 308
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   456 ARLVN-ELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKfvakENEVQSLHS 534
Cdd:TIGR04523  309 NKELKsELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKL----KKENQSYKQ 384
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   535 KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA----AQTSASVLAEELHKVIA 610
Cdd:TIGR04523  385 EIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKdltnQDSVKELIIKNLDNTRE 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   611 EKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANeqaaaahELEKMQQSVYVKDDKIRLLEEQLQ 690
Cdd:TIGR04523  465 SLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK-------DLTKKISSLKEKIEKLESEKKEKE 537
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   691 HEISNKMEEFKILNDQNKALKLEV------QKLQTLVSEQPN-KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEE 763
Cdd:TIGR04523  538 SKISDLEDELNKDDFELKKENLEKeideknKEIEELKQTQKSlKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEK 617
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 383418275   764 ELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 806
Cdd:TIGR04523  618 ELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
609-1049 1.13e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.18  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   609 IAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKmqqsvyvKDDKIRLLEEQ 688
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK-------NIDKIKNKLLK 198
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   689 LQHEISN---KMEEFKILNDQNKALKLEVQKLQTLVSEqpNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEEL 765
Cdd:TIGR04523  199 LELLLSNlkkKIQKNKSLESQISELKKQNNQLKDNIEK--KQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKEL 276
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   766 NAIRTENSSLTKEVQDLKAKQND--QVSFASLVEELKKVIHEKDGKIKSVEElleaellKVANKEKTVQDLKQEIKALKE 843
Cdd:TIGR04523  277 EQNNKKIKELEKQLNQLKSEISDlnNQKEQDWNKELKSELKNQEKKLEEIQN-------QISQNNKIISQLNEQISQLKK 349
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   844 EIGNVQLEKAQ-QLSITSQVQELQNLLKGKEE----------QMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912
Cdd:TIGR04523  350 ELTNSESENSEkQRELEEKQNEIEKLKKENQSykqeiknlesQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   913 EVAQHNLKEVSSAS-----------QFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLK 981
Cdd:TIGR04523  430 RLKETIIKNNSEIKdltnqdsvkelIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELE 509
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275   982 QQ----NYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAV--EHQRKKNNERQQQVEAVELEAKEVLKK 1049
Cdd:TIGR04523  510 EKvkdlTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKK 583
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
435-1050 1.44e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.18  E-value: 1.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQE--AERRWEEVQ-SYIRKRTAEH 511
Cdd:TIGR04523   85 KDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKflTEIKKKEKElEKLNNKYNDL 164
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   512 EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLmeseQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQ 591
Cdd:TIGR04523  165 KKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNL----KKKIQKNKSLESQISELKKQNNQLKDNIEKKQQE 240
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   592 IaaqtsasvlaEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQAlaneqaaaahelekm 671
Cdd:TIGR04523  241 I----------NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKS--------------- 295
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   672 qqsvyvkddKIRLLEEQLQHEISNKMEEFkILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEEll 751
Cdd:TIGR04523  296 ---------EISDLNNQKEQDWNKELKSE-LKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQR-- 363
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   752 etgliQVATKEEELNAIRTENSSLTKEVQDLKAKQNDqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTV 831
Cdd:TIGR04523  364 -----ELEEKQNEIEKLKKENQSYKQEIKNLESQIND---LESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETI 435
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   832 QDLKQEIKALKEEIGNVQLEKAQQLSITSQvqeLQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV 911
Cdd:TIGR04523  436 IKNNSEIKDLTNQDSVKELIIKNLDNTRES---LETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKV 512
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   912 QEVAQhnlKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLssKTKLLQDVQDENklfKSQIEQLKQQNYQQASSf 991
Cdd:TIGR04523  513 KDLTK---KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL--KKENLEKEIDEK---NKEIEELKQTQKSLKKK- 583
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 383418275   992 ppHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKL 1050
Cdd:TIGR04523  584 --QEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKK 640
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1085-1295 7.32e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 7.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1085 EVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLR 1164
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1165 RENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAA 1244
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 383418275 1245 GDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEH 1295
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
829-1049 1.04e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  829 KTVQDLKQEIKALKEEIGNVQLEKAQQlsiTSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAAL---KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  909 AHVQEVaQHNLKEVSSA----SQFEELEIVLKEKENE--------LKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQ 976
Cdd:COG4942    97 AELEAQ-KEELAELLRAlyrlGRQPPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 383418275  977 IEQLKQQNYQQassfppHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKK 1049
Cdd:COG4942   176 LEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
326-841 1.10e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  326 ELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIARM---KDRIGTLEKEHNVFQNKIhvsyQETQ 402
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEyelLAELARLEQDIARLEERR----RELE 315
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  403 QMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQA 482
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE-AELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  483 VTQLKVQLQEAERRWEEvqsyIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVN 562
Cdd:COG1196   395 AAELAAQLEELEEAEEA----LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  563 KEESLQMQVQDILEQNEALKAQIQQFHSQIA--AQTSASVLAEELHKVIAEKDKQIKQ-TEDSLANERDHLTSKEEELKD 639
Cdd:COG1196   471 EAALLEAALAELLEELAEAAARLLLLLEAEAdyEGFLEGVKAALLLAGLRGLAGAVAVlIGVEAAYEAALEAALAAALQN 550
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKIlndqnKALKLEVQKLQT 719
Cdd:COG1196   551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA-----RYYVLGDTLLGR 625
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  720 LVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEEL 799
Cdd:COG1196   626 TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275  800 KKVIHEKDGKIKSVEELLEAELLKVANK--------------------------------EKTVQDLKQEIKAL 841
Cdd:COG1196   706 ERELAEAEEERLEEELEEEALEEQLEAEreelleelleeeelleeealeelpeppdleelERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
920-1246 1.69e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  920 KEVSSASQFEELEIVLKEKENEL-----KRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQnyqqassfppH 994
Cdd:COG1196   207 RQAEKAERYRELKEELKELEAELlllklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE----------L 276
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  995 EELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLfpkvsvpsnlsysewlHGFEKKAK 1074
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL----------------EELEEELE 340
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1075 ECmagtsgSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKwkvkVDESHKTIKQMQSSFT 1154
Cdd:COG1196   341 EL------EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA----AAELAAQLEELEEAEE 410
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1155 SSEQELERLRRE----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQ 1230
Cdd:COG1196   411 ALLERLERLEEEleelEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
                         330
                  ....*....|....*.
gi 383418275 1231 QSLELIQSKIVKAAGD 1246
Cdd:COG1196   491 ARLLLLLEAEADYEGF 506
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
448-1275 2.75e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 2.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   448 LNKLRQDYARLVNELTEKTGKLQQ-EEVQKKNAEQAVTQLKVQLQEAERRwEEVQSYIRKRTAEheaAQQDLQSKFVAKE 526
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESNElHEKQKFYLRQSVIDLQTKLQEMQME-RDAMADIRRRESQ---SQEDLRNQLQNTV 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   527 NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEqkrvnkeESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASvLAEELH 606
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-------EGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRS-LGSAIS 223
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   607 KVIAEKDKQIKQTEDSLANERDHLTSKEEELKDiqNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQN--KIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   687 EQLQHEISNkmeefkilndQNKALKLEVQKLQTLVSEQPNkdvveqmekciqEKDEKLKTVEELLETGLIQVATKEEELN 766
Cdd:pfam15921  302 EIIQEQARN----------QNSMYMRQLSDLESTVSQLRS------------ELREAKRMYEDKIEELEKQLVLANSELT 359
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   767 AIRTENSSLTKEVQDLkakqNDQVsfaslvEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEig 846
Cdd:pfam15921  360 EARTERDQFSQESGNL----DDQL------QKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNME-- 427
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   847 nvqlekaqqlsitsqVQELQNLLKGKEE----QMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEV 922
Cdd:pfam15921  428 ---------------VQRLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE 492
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   923 SSASQFEELEIVLKEKENELK-----------RVEAMLKERESdLSSKTKLLQDVQDENKLFKSQ-------IEQLKQQN 984
Cdd:pfam15921  493 SSERTVSDLTASLQEKERAIEatnaeitklrsRVDLKLQELQH-LKNEGDHLRNVQTECEALKLQmaekdkvIEILRQQI 571
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   985 YQQASSFPPHEELLKVI----SEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLkklfpkvsvpsnl 1060
Cdd:pfam15921  572 ENMTQLVGQHGRTAGAMqvekAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLV------------- 638
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1061 sysewlhgfekkakecmagTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEE---NKWKV 1137
Cdd:pfam15921  639 -------------------NAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttNKLKM 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1138 KVDESHKTIKQMQSSFTSSE----QELERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLR 1213
Cdd:pfam15921  700 QLKSAQSELEQTRNTLKSMEgsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELS 779
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275  1214 TEQNERQKVAGDLHKAQQSLELIQSKI--VKAAGDITVIENSDVSPETESSEKETMSVSLNQTV 1275
Cdd:pfam15921  780 TVATEKNKMAGELEVLRSQERRLKEKVanMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTL 843
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
824-1204 2.77e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 2.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   824 VANKEKTVQDLKQEIKALKEEIGNVQL---EKAQQLSITS----QVQELQNLLKGKEEQMNTMKAV-LEEKEKDLANTGK 895
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRrereKAERYQALLKEKREYEGYELLKeKEALERQKEAIER 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   896 WLQDLQEENESLKAHVQEVAQhnlkevssasQFEELEIVLKEKENELKRV----EAMLKERESDLSSKTKLLQDVQDENK 971
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEK----------RLEEIEQLLEELNKKIKDLgeeeQLRVKEKIGELEAEIASLERSIAEKE 314
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   972 lfksqiEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLf 1051
Cdd:TIGR02169  315 ------RELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL- 387
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1052 pkvsvpsnLSYSEWLHGFEKKakecmagtsgseevkvLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQE 1131
Cdd:TIGR02169  388 --------KDYREKLEKLKRE----------------INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEK 443
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 383418275  1132 ENKWKvKVDESHKTIKQMQSSFTSSEQELERLRRENKDIEnlrREREHLEMELEKAEMERSTYVTEVRELKAQ 1204
Cdd:TIGR02169  444 EDKAL-EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE---KELSKLQRELAEAEAQARASEERVRGGRAV 512
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
741-1253 3.14e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 3.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAkqndqvsFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Cdd:PRK03918  192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE-------LKEEIEELEKELESLEGSKRKLEEKIREL 264
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  821 LLKVANKEKTVQDLKQEIKALKEeignvqlekaqqlsitsqvqelqnlLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 900
Cdd:PRK03918  265 EERIEELKKEIEELEEKVKELKE-------------------------LKEKAEEYIKLSEFYEEYLDELREIEKRLSRL 319
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  901 QEENESLKAHVQEVAQhnlkevssasqfeeleivLKEKENELKRVEAMLKERESDLSSKTKLLQDVqdenKLFKSQIEQL 980
Cdd:PRK03918  320 EEEINGIEERIKELEE------------------KEERLEELKKKLKELEKRLEELEERHELYEEA----KAKKEELERL 377
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  981 KQQnyqqaSSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAveleakevLKKLFPKVSVPSNL 1060
Cdd:PRK03918  378 KKR-----LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE--------LKKAKGKCPVCGRE 444
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1061 SYsewlhgfEKKAKECMAgtSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQ-----RSVEQEENKW 1135
Cdd:PRK03918  445 LT-------EEHRKELLE--EYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaeqlKELEEKLKKY 515
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1136 KV-KVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELK----AQLNETLT 1210
Cdd:PRK03918  516 NLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfesvEELEERLK 595
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 383418275 1211 KLRT---EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENS 1253
Cdd:PRK03918  596 ELEPfynEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKR 641
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
442-1037 5.88e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.88  E-value: 5.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   442 SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQkknAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSK 521
Cdd:pfam05483  172 KKYEYEREETRQVYMDLNNNIEKMILAFEELRVQ---AENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQ 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDIleqnealKAQIQQ-FHSQIAAQTSASV 600
Cdd:pfam05483  249 ITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI-------KMSLQRsMSTQKALEEDLQI 321
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   601 LAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNmnfLLKAEVQKLQALANEQAAAAHELEKmQQSVYVKDD 680
Cdd:pfam05483  322 ATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE---LLRTEQQRLEKNEDQLKIITMELQK-KSSELEEMT 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   681 KIRLLEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTlvSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVAT 760
Cdd:pfam05483  398 KFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKG--KEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVED 475
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFAS-LVEELKKviHEKDgkIKSVEELLEAELLKVANKEKTVQDLKQEIK 839
Cdd:pfam05483  476 LKTELEKEKLKNIELTAHCDKLLLENKELTQEASdMTLELKK--HQED--IINCKKQEERMLKQIENLEEKEMNLRDELE 551
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   840 ALKEEIGNVQLEKAQQLSITSQ-VQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKA--------- 909
Cdd:pfam05483  552 SVREEFIQKGDEVKCKLDKSEEnARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKkgsaenkql 631
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   910 HVQEVAQHNLK-EVSSASQFEELEIVLKEKENELKRV-----------------EAMLKERESDLSSKTKLLQDVQDENK 971
Cdd:pfam05483  632 NAYEIKVNKLElELASAKQKFEEIIDNYQKEIEDKKIseeklleevekakaiadEAVKLQKEIDKRCQHKIAEMVALMEK 711
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 383418275   972 LFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVE 1037
Cdd:pfam05483  712 HKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
823-1251 6.04e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 6.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  823 KVANKEKTVQDLKQEIKALKEEIGnvqlekaqqlSITSQVQELQNLLKGKEEQmntmkavLEEKEKDLANTGKWLQDLQE 902
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLE----------KFIKRTENIEELIKEKEKE-------LEEVLREINEISSELPELRE 221
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  903 ENESLKAHVQEVAQHnlkevssASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEqlKQ 982
Cdd:PRK03918  222 ELEKLEKEVKELEEL-------KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE--KA 292
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  983 QNYQQASSFppHEELLKVISEREKEISGLWNELDSlkdaVEHQRKKNNERQQQVEAVELEAKEVLKKLfpKVSVPSNLSY 1062
Cdd:PRK03918  293 EEYIKLSEF--YEEYLDELREIEKRLSRLEEEING----IEERIKELEEKEERLEELKKKLKELEKRL--EELEERHELY 364
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1063 SEWLHgfEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQ-EENKWKVKV-- 1139
Cdd:PRK03918  365 EEAKA--KKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElKKAKGKCPVcg 442
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1140 ---DESHKtiKQMQSSFTSseqELERLRRENKDIENLRREREHLEMELEKaEMERSTYVTEVRELKAQLNETLTKLRTEQ 1216
Cdd:PRK03918  443 relTEEHR--KELLEEYTA---ELKRIEKELKEIEEKERKLRKELRELEK-VLKKESELIKLKELAEQLKELEEKLKKYN 516
                         410       420       430
                  ....*....|....*....|....*....|....*
gi 383418275 1217 NErqkvagDLHKAQQSLELIQSKIVKAAGDITVIE 1251
Cdd:PRK03918  517 LE------ELEKKAEEYEKLKEKLIKLKGEIKSLK 545
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
349-781 6.62e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 50.82  E-value: 6.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  349 AATKDRCKQLTQEMmsEKERSNVVIARmKDRIGTLEKEHNVFQNKihvsyQETQQMQMKFQQVREQMEAEIAHLKQENGI 428
Cdd:PRK10929   19 AATAPDEKQITQEL--EQAKAAKTPAQ-AEIVEALQSALNWLEER-----KGSLERAKQYQQVIDNFPKLSAELRQQLNN 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  429 LRDAVSNttnqLESKQSAelNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRT 508
Cdd:PRK10929   91 ERDEPRS----VPPNMST--DALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLQTLG 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  509 AEHEAAQqdlQSKFVAKENEVQSLHSKLtdtlvskQQLEqrLMQLMESeqkrvNKEESLQMQVQDILEQNEALKAQIQQF 588
Cdd:PRK10929  165 TPNTPLA---QAQLTALQAESAALKALV-------DELE--LAQLSAN-----NRQELARLRSELAKKRSQQLDAYLQAL 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  589 HSQIAAQ---------TSASVLAE---ELHKVIAEKDKQIKQTEDSL---ANERDHLTSKE-----EELKDIQNMNFL-- 646
Cdd:PRK10929  228 RNQLNSQrqreaeralESTELLAEqsgDLPKSIVAQFKINRELSQALnqqAQRMDLIASQQrqaasQTLQVRQALNTLre 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  647 --------------LKAEVQKLQalaneqaaaahELEKMQQsvyVKDDKIRLLEEQLQHEisnkmeefKILNDQNKALKL 712
Cdd:PRK10929  308 qsqwlgvsnalgeaLRAQVARLP-----------EMPKPQQ---LDTEMAQLRVQRLRYE--------DLLNKQPQLRQI 365
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275  713 EVQKLQTLVSEQpnkdvveqmeKCIQekDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLT---KEVQD 781
Cdd:PRK10929  366 RQADGQPLTAEQ----------NRIL--DAQLRTQRELLNSLLSGGDTLILELTKLKVANSQLEdalKEVNE 425
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
296-635 7.38e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 7.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   296 FSEDEALCVVDLLKEKSGVIQDALKKSSKgELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIAR 375
Cdd:pfam12128  597 ASEEELRERLDKAEEALQSAREKQAAAEE-QLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE 675
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   376 MKD----RIGTLEKEHNVFQNKIHVSYQETQ--------QMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESK 443
Cdd:pfam12128  676 RKDsaneRLNSLEAQLKQLDKKHQAWLEEQKeqkreartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW 755
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   444 QSAELNKLRQD---YARLVNELTEKTGKLQQEEVQkknaEQAVTQLKVQLQEaerRWEEVQSYIRKRTAEHEAAQQDLQS 520
Cdd:pfam12128  756 YKRDLASLGVDpdvIAKLKREIRTLERKIERIAVR----RQEVLRYFDWYQE---TWLQRRPRLATQLSNIERAISELQQ 828
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL---MESEQKRVNK------EESLQM-------QVQDILEQNEALKAQ 584
Cdd:pfam12128  829 QLARLIADTKLRRAKLEMERKASEKQQVRLSENlrgLRCEMSKLATlkedanSEQAQGsigerlaQLEDLKLKRDYLSES 908
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 383418275   585 IQQFHSQ---IAAQTSASVLAEELHKvIAEKDKQIKQTEDSLANERDHLTSKEE 635
Cdd:pfam12128  909 VKKYVEHfknVIADHSGSGLAETWES-LREEDHYQNDKGIRLLDYRKLVPYLEQ 961
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
757-1300 7.87e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 7.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   757 QVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVS----FASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTeikkKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID 190
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   833 DLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   913 EvaqhnlkevsSASQFEELEIVLKEKENELKRVEAMLKERESdlssktkllQDVQDENKLFKSQIEQLKQQNyqqassfp 992
Cdd:TIGR04523  271 E----------KQKELEQNNKKIKELEKQLNQLKSEISDLNN---------QKEQDWNKELKSELKNQEKKL-------- 323
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   993 phEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKlfpkvsvpsNLSYSEWLHGFEKK 1072
Cdd:TIGR04523  324 --EEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE---------NQSYKQEIKNLESQ 392
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1073 AKECMAGTSGSEEV-KVLEHKLKEADEMHTLLQLECEKYKS---VLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQ 1148
Cdd:TIGR04523  393 INDLESKIQNQEKLnQQKDEQIKKLQQEKELLEKEIERLKEtiiKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKV 472
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1149 MQSSFTSSEQELERLRRE----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAG 1224
Cdd:TIGR04523  473 LSRSINKIKQNLEQKQKElkskEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF 552
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 383418275  1225 DLHKAQQSLEL--IQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE 1300
Cdd:TIGR04523  553 ELKKENLEKEIdeKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLS 630
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
430-969 8.40e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 8.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  430 RDAVSNTTNQLESKQSAE----LNKLRQdyarlvnELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQsyir 505
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDlherLNGLES-------ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE---- 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  506 krtaEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEAL---- 581
Cdd:PRK02224  255 ----TLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELrdrl 330
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  582 ---KAQIQQFHSQI-AAQTSASVL---AEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDiqNMNFLLKAEVQkL 654
Cdd:PRK02224  331 eecRVAAQAHNEEAeSLREDADDLeerAEELREEAAELESELEEAREAVEDRREEIEELEEEIEE--LRERFGDAPVD-L 407
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  655 QALANEQAAAAHELEKMQQSVYVKDDKIRLLE------EQLQHE------------------ISNKMEEFKILNDQNKAL 710
Cdd:PRK02224  408 GNAEDFLEELREERDELREREAELEATLRTARerveeaEALLEAgkcpecgqpvegsphvetIEEDRERVEELEAELEDL 487
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  711 KLEVQKLQTLVSEQpnKDVVEQmEKCIQEKDEKLKTVEELLEtgliqvaTKEEELNAIRTENSSLTKEVQDLKAKQNDQV 790
Cdd:PRK02224  488 EEEVEEVEERLERA--EDLVEA-EDRIERLEERREDLEELIA-------ERRETIEEKRERAEELRERAAELEAEAEEKR 557
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVAnkekTVQDLKQEIKALKEEIGNVQlEKAQQLsitsqvQELQNLLK 870
Cdd:PRK02224  558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESLE----RIRTLLAAIADAEDEIERLR-EKREAL------AELNDERR 626
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  871 GKEEQMNTMKAVLEEKEKDLAntgkwLQDLQEENESLKAHVQEVAQhNLKEVssASQFEELEIVLKEKENELKRVEAmLK 950
Cdd:PRK02224  627 ERLAEKRERKRELEAEFDEAR-----IEEAREDKERAEEYLEQVEE-KLDEL--REERDDLQAEIGAVENELEELEE-LR 697
                         570
                  ....*....|....*....
gi 383418275  951 ERESDLSSKTKLLQDVQDE 969
Cdd:PRK02224  698 ERREALENRVEALEALYDE 716
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
826-1050 1.32e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.54  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  826 NKEKTVQDLKQ----EIKALKEEIGNVQLEKAQQLSIT-----SQVQELQNLLKGKEEQMNTMK-----AVLEEKEKDLA 891
Cdd:PRK05771   17 YKDEVLEALHElgvvHIEDLKEELSNERLRKLRSLLTKlsealDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  892 NTGKWLQDLQEENESLKAHVQEVaQHNLKEVSSASQFEELEIVLKEKEN---ELKRVEAMLKERESDLSSKTKLLQDVQD 968
Cdd:PRK05771   97 KIEKEIKELEEEISELENEIKEL-EQEIERLEPWGNFDLDLSLLLGFKYvsvFVGTVPEDKLEELKLESDVENVEYISTD 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  969 ENKLF----------KSQIEQLKQQNYQQASsFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEA 1038
Cdd:PRK05771  176 KGYVYvvvvvlkelsDEVEEELKKLGFERLE-LEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYE 254
                         250
                  ....*....|....*
gi 383418275 1039 V---ELEAKEVLKKL 1050
Cdd:PRK05771  255 YleiELERAEALSKF 269
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
442-643 1.37e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  442 SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDL--Q 519
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELeaQ 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  520 SKFVAKENEVQSLHSKLTDTLV-----SKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA 594
Cdd:COG4942   103 KEELAELLRALYRLGRQPPLALllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 383418275  595 QTSAsvlAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNM 643
Cdd:COG4942   183 LEEE---RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
757-983 1.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  757 QVATKEEELNAIRTENSSLTKEVQDLKAKQndqvsfASLVEELKKVihekDGKIKSVEELLEAELLKVANKEKTVQDLKQ 836
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEE------KALLKQLAAL----ERRIAALARRIRALEQELAALEAELAELEK 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  837 EIKALKEEIGNVQLEKAQQLSI---TSQVQELQNLLKGKEeqmntmkavLEEKEKDLANTGKWLQDLQEENESLKAHVQE 913
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRAlyrLGRQPPLALLLSPED---------FLDAVRRLQYLKYLAPARREQAEELRADLAE 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  914 VAQhnlKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQ 983
Cdd:COG4942   162 LAA---LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
509-1181 1.54e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   509 AEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALkAQIQQF 588
Cdd:TIGR00618  194 GKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLR-ARIEEL 272
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   589 HSQIAAQTSASVLAEELHKV--IAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAH 666
Cdd:TIGR00618  273 RAQEAVLEETQERINRARKAapLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHS 352
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   667 ELEKMQQSVYVKDDKIRLLEEQ--LQHEISNKMEEFKILNDQNKALKlevQKLQTLVSEQPNKDVVEQMEKCIQEKDEKL 744
Cdd:TIGR00618  353 QEIHIRDAHEVATSIREISCQQhtLTQHIHTLQQQKTTLTQKLQSLC---KELDILQREQATIDTRTSAFRDLQGQLAHA 429
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   745 KTVEEL-LETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK--QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL 821
Cdd:TIGR00618  430 KKQQELqQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEReqQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   822 LKVANKEKT-----------VQDLKQEIKALKEEIGNV----QLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEK 886
Cdd:TIGR00618  510 CIHPNPARQdidnpgpltrrMQRGEQTYAQLETSEEDVyhqlTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   887 EKDLANTGKWLQDLQEENESLKAHVQ------EVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKT 960
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHallrklQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRV 669
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   961 ---KLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVE 1037
Cdd:TIGR00618  670 lpkELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1038 AvelEAKEVLKKlfpkvsvpsnlSYSEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAET 1117
Cdd:TIGR00618  750 H---QARTVLKA-----------RTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSD 815
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275  1118 EGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREHLE 1181
Cdd:TIGR00618  816 EDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLN 879
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
612-1294 2.49e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.02  E-value: 2.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   612 KDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIrlleEQLQH 691
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQEL----EEILH 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   692 EISNKMEEFKilnDQNKALKLEVQKLQTLVseqpnKDVVEQMEkciQEKDEKLKTVEELLeTGLIQVATKEEELNAIRTE 771
Cdd:pfam01576   79 ELESRLEEEE---ERSQQLQNEKKKMQQHI-----QDLEEQLD---EEEAARQKLQLEKV-TTEAKIKKLEEDILLLEDQ 146
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   772 NSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKvanKEKTVQDLKQEIKALKEEIGNVQle 851
Cdd:pfam01576  147 NSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKK---EEKGRQELEKAKRKLEGESTDLQ-- 221
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   852 kAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV-QEVAQHNLKEVSSASQFEE 930
Cdd:pfam01576  222 -EQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLeSERAARNKAEKQRRDLGEE 300
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   931 LEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEE--------LLKVIS 1002
Cdd:pfam01576  301 LEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEqakrnkanLEKAKQ 380
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1003 EREKEISGLWNELDSL---KDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNL--SYSEWLHGFEKKAkecm 1077
Cdd:pfam01576  381 ALESENAELQAELRTLqqaKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSEleSVSSLLNEAEGKN---- 456
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1078 agTSGSEEVKVLEHKLKEADEmhtLLQLECE---KYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFT 1154
Cdd:pfam01576  457 --IKLSKDVSSLESQLQDTQE---LLQEETRqklNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1155 SSEQELERLRRENKDIENLRREREHLEMELEkaemERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLE 1234
Cdd:pfam01576  532 KLEEDAGTLEALEEGKKRLQRELEALTQQLE----EKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFD 607
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 383418275  1235 --LIQSKIVKAagdiTVIENSDVSpETESSEKETMSVSLNQTVTQLQQL---LQAVNQQLTKEKE 1294
Cdd:pfam01576  608 qmLAEEKAISA----RYAEERDRA-EAEAREKETRALSLARALEEALEAkeeLERTNKQLRAEME 667
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
354-982 3.16e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.50  E-value: 3.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   354 RCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQ------------QVREQMEAEIAH 421
Cdd:TIGR00606  323 DCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLEldgfergpfserQIKNFHTLVIER 402
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   422 LKQENGILRDAVSNTTNQLESKQSAeLNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVq 501
Cdd:TIGR00606  403 QEDEAKTAAQLCADLQSKERLKQEQ-ADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQEL- 480
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   502 syirkRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEeslqMQVQDILEQNEAL 581
Cdd:TIGR00606  481 -----RKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQME----MLTKDKMDKDEQI 551
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLKAEVQKL------- 654
Cdd:TIGR00606  552 RKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYedklfdv 631
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   655 ---QALANEQAAAAHELEKMQQSVYVKDDKIRLLE---EQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQPNKd 728
Cdd:TIGR00606  632 cgsQDEESDLERLKEEIEKSSKQRAMLAGATAVYSqfiTQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDK- 710
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   729 vVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLK---AKQNDQVSFASLVEELKKVIHE 805
Cdd:TIGR00606  711 -LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKndiEEQETLLGTIMPEEESAKVCLT 789
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   806 KDGKIKSVEELLEAELLKVANkektvqdlkqeikalkeeignvQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEE 885
Cdd:TIGR00606  790 DVTIMERFQMELKDVERKIAQ----------------------QAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIEL 847
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   886 KEKdlantgkWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQD 965
Cdd:TIGR00606  848 NRK-------LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEK 920
                          650
                   ....*....|....*..
gi 383418275   966 VQDENKLFKSQIEQLKQ 982
Cdd:TIGR00606  921 DQQEKEELISSKETSNK 937
PRK12704 PRK12704
phosphodiesterase; Provisional
825-953 3.61e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.85  E-value: 3.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  825 ANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLsitsqvQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN 904
Cdd:PRK12704   53 AIKKEALLEAKEEIHKLRNEFEKELRERRNEL------QKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQEL 126
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 383418275  905 ESLKAHVQE-VAQHN--LKEVSSASQFEELEIVLKEKENELKR-VEAMLKERE 953
Cdd:PRK12704  127 EKKEEELEElIEEQLqeLERISGLTAEEAKEILLEKVEEEARHeAAVLIKEIE 179
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
319-891 3.84e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 3.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   319 LKKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKIHVSY 398
Cdd:pfam12128  263 LHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETA 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   399 QETQQMQMKFQQVREQMEAEIAHLKQENGilrdAVSNTTNQLESKQSAELNKlrqDYARLVNEL-TEKTGKLQQEEVQKK 477
Cdd:pfam12128  343 AADQEQLPSWQSELENLEERLKALTGKHQ----DVTAKYNRRRSKIKEQNNR---DIAGIKDKLaKIREARDRQLAVAED 415
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   478 NAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHE------AAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLM 551
Cdd:pfam12128  416 DLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnqaTATPELLLQLENFDERIERAREEQEAANAEVERLQSELR 495
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   552 QLmesEQKRVNKEESLQMQVQDILEQNEALKAQIQQF----HSQIA-AQTSASVLAEELHKVIA-----------EKDKQ 615
Cdd:pfam12128  496 QA---RKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHfLRKEAPDWEQSIGKVISpellhrtdldpEVWDG 572
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   616 IKQTEDSLANERDHLtsKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN 695
Cdd:pfam12128  573 SVGGELNLYGVKLDL--KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN 650
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   696 KMEEFKILNDQNKALKLEVQklQTLVSEQpnKDVVEQMEKCIQEKDEKLKTVEELLEtgliqvATKEEELNAIRTENSSL 775
Cdd:pfam12128  651 ARLDLRRLFDEKQSEKDKKN--KALAERK--DSANERLNSLEAQLKQLDKKHQAWLE------EQKEQKREARTEKQAYW 720
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   776 TKEVQDLKAKqndqvsFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQ 855
Cdd:pfam12128  721 QVVEGALDAQ------LALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEV 794
                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 383418275   856 LSITSQVQELQNLLKGK-EEQMNTMKAVLEEKEKDLA 891
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRlATQLSNIERAISELQQQLA 831
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
823-1240 5.36e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 5.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  823 KVANKEKTVQDLKQEIKALKEEIGnvQLEKAQQL-SITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Cdd:COG4717    96 ELEELEEELEELEAELEELREELE--KLEKLLQLlPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELA 173
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  902 EENESLKAHVQEVAQHNLKEVSSAS-QFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFK------ 974
Cdd:COG4717   174 ELQEELEELLEQLSLATEEELQDLAeELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarllll 253
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  975 --SQIEQLKQQNYQQASSFPPHEELLKVISerekeisGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFP 1052
Cdd:COG4717   254 iaAALLALLGLGGSLLSLILTIAGVLFLVL-------GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLA 326
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1053 KVSVPSNLSYSEWLHGFEKkakecmagtsgSEEVKVLEHKLKEADEMHTLLQLEcEKYKSVLAET-----EGILQKLQRS 1127
Cdd:COG4717   327 ALGLPPDLSPEELLELLDR-----------IEELQELLREAEELEEELQLEELE-QEIAALLAEAgvedeEELRAALEQA 394
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1128 VEQEENKWKVKVDEShktikQMQSSFTSSEQELERLrrenkDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLN- 1206
Cdd:COG4717   395 EEYQELKEELEELEE-----QLEELLGELEELLEAL-----DEEELEEELEELEEELEELEEELEELREELAELEAELEq 464
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 383418275 1207 ----ETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1240
Cdd:COG4717   465 leedGELAELLQELEELKAELRELAEEWAALKLALELL 502
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
685-1251 5.82e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 47.74  E-value: 5.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   685 LEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQtlvsEQPNKDVVeQMEKCIQEK-DEKLKTVEELLETGLIQVATKEE 763
Cdd:TIGR01612  534 IKAKLYKEIEAGLKESYELAKNWKKLIHEIKKEL----EEENEDSI-HLEKEIKDLfDKYLEIDDEIIYINKLKLELKEK 608
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   764 ELNaIRTENSSLTKEVqdlkakqndqvsfaslveELKKVIHEKDGKIKSVEELLEAELLK-VANKEKTVQDLKQEikalk 842
Cdd:TIGR01612  609 IKN-ISDKNEYIKKAI------------------DLKKIIENNNAYIDELAKISPYQVPEhLKNKDKIYSTIKSE----- 664
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   843 eeignvqLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLqeENESLKAHVQEVaqHNLKEV 922
Cdd:TIGR01612  665 -------LSKIYEDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNM--ETATVELHLSNI--ENKKNE 733
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   923 SSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS-----------SF 991
Cdd:TIGR01612  734 LLDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYNDQINidnikdedakqNY 813
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   992 PPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKK----NNERQQQVEAVELEAKEVLKKLFPKVSvpsnlsySEWLH 1067
Cdd:TIGR01612  814 DKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKfinfENNCKEKIDSEHEQFAELTNKIKAEIS-------DDKLN 886
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1068 GFEKK---AKECMAGTSGSEEvkvlehklKEADEMHTLLQLecEKYKSVLAETEGILQKLQrsveQEENKWKVKVDESHK 1144
Cdd:TIGR01612  887 DYEKKfndSKSLINEINKSIE--------EEYQNINTLKKV--DEYIKICENTKESIEKFH----NKQNILKEILNKNID 952
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1145 TIKQMQSSFTSSEQELERLRRENKDienlrrerehlemELEKA--EMERSTYVTEVRELKAQLNETLTKLRTeqNERQKV 1222
Cdd:TIGR01612  953 TIKESNLIEKSYKDKFDNTLIDKIN-------------ELDKAfkDASLNDYEAKNNELIKYFNDLKANLGK--NKENML 1017
                          570       580
                   ....*....|....*....|....*....
gi 383418275  1223 AGDLHKAQQSLELIQSKIVKAAGDITVIE 1251
Cdd:TIGR01612 1018 YHQFDEKEKATNDIEQKIEDANKNIPNIE 1046
PRK12704 PRK12704
phosphodiesterase; Provisional
929-1049 7.73e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 7.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  929 EELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQassfppHEELLKVISEREKE- 1007
Cdd:PRK12704   71 NEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKK------EEELEELIEEQLQEl 144
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 383418275 1008 --ISGLWNE------LDSLKDAVEHqrkknnERQQQVEAVELEAKEVLKK 1049
Cdd:PRK12704  145 erISGLTAEeakeilLEKVEEEARH------EAAVLIKEIEEEAKEEADK 188
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
305-1286 9.10e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 47.35  E-value: 9.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   305 VDLLK--EKSGVIQDALKKSSKGELTtlvHQLQEKDKLLAAVKEDAAAT-KDRCKQLTQEMMSEKERSNVVIARMKDRIG 381
Cdd:TIGR01612  623 IDLKKiiENNNAYIDELAKISPYQVP---EHLKNKDKIYSTIKSELSKIyEDDIDALYNELSSIVKENAIDNTEDKAKLD 699
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   382 TLekehnvfQNKIHVSYQETQQMQMkfqqvrEQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNE 461
Cdd:TIGR01612  700 DL-------KSKIDKEYDKIQNMET------ATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLNKILEDFKNKEKE 766
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   462 LTEKTGKLQQEEVQKKNAEQAVTQLKVQL-----------QEAERRWEEVQSYIR----------KRTAEHEAAQQDLQS 520
Cdd:TIGR01612  767 LSNKINDYAKEKDELNKYKSKISEIKNHYndqinidnikdEDAKQNYDKSKEYIKtisikedeifKIINEMKFMKDDFLN 846
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   521 K---FVAKEN----EVQSLHSKLTDtLVSKQQLEQRLMQLMESEqKRVNKEESLqmqvqdILEQNEALKAQIQQFHSQia 593
Cdd:TIGR01612  847 KvdkFINFENnckeKIDSEHEQFAE-LTNKIKAEISDDKLNDYE-KKFNDSKSL------INEINKSIEEEYQNINTL-- 916
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   594 aqtsasvlaeelhKVIAEKDKQIKQTEDSLANERDHLTSKEEEL----KDIQNMNFLLKAEVQKLQALANEQAAaahELE 669
Cdd:TIGR01612  917 -------------KKVDEYIKICENTKESIEKFHNKQNILKEILnkniDTIKESNLIEKSYKDKFDNTLIDKIN---ELD 980
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   670 KMqqsvyvkddkirLLEEQLQHEISNKMEEFKILNDQNKalKLEVQKLQTLVSE-QPNKDVVEQMEKCIQEKDEKLKTVE 748
Cdd:TIGR01612  981 KA------------FKDASLNDYEAKNNELIKYFNDLKA--NLGKNKENMLYHQfDEKEKATNDIEQKIEDANKNIPNIE 1046
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   749 ELLETGLIQVAtkEEELNAIRTENSSLTKEVqdLKAKQNDQVSFASLVEELKkvIHEKDGKIKSVEELLEAELLKVANKE 828
Cdd:TIGR01612 1047 IAIHTSIYNII--DEIEKEIGKNIELLNKEI--LEEAEINITNFNEIKEKLK--HYNFDDFGKEENIKYADEINKIKDDI 1120
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   829 KTV-QDLKQEIKALkEEIGNVQLEKAQQlsITSQVQELQNL---------LKGKEEQMNTMKAVLEEKEKDLANTGKWLQ 898
Cdd:TIGR01612 1121 KNLdQKIDHHIKAL-EEIKKKSENYIDE--IKAQINDLEDVadkaisnddPEEIEKKIENIVTKIDKKKNIYDEIKKLLN 1197
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   899 DLQEEnESLKAHVQEVAQHNLKEVSSASQF--EELEIVLKEKENELKRVEAML------KERESDLSSKTKLLQDVQDEN 970
Cdd:TIGR01612 1198 EIAEI-EKDKTSLEEVKGINLSYGKNLGKLflEKIDEEKKKSEHMIKAMEAYIedldeiKEKSPEIENEMGIEMDIKAEM 1276
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   971 KLF------------------------KSQIEQLKQQNYQQASSFPPHEELLKVISEREK----------EISGLWN--E 1014
Cdd:TIGR01612 1277 ETFnishdddkdhhiiskkhdenisdiREKSLKIIEDFSEESDINDIKKELQKNLLDAQKhnsdinlylnEIANIYNilK 1356
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1015 LDSLKDAVEHQRKKNNERQQQVEAV--ELEAKEVLKKlfpkvSVPSNLSYSEWLHGFE-----KKAKECMAGTSGSEEVK 1087
Cdd:TIGR01612 1357 LNKIKKIIDEVKEYTKEIEENNKNIkdELDKSEKLIK-----KIKDDINLEECKSKIEstlddKDIDECIKKIKELKNHI 1431
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1088 VLEHK-----LKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEE----NKWKVKVDESHKTIKQMQSSFTSSEQ 1158
Cdd:TIGR01612 1432 LSEESnidtyFKNADENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHdfniNELKEHIDKSKGCKDEADKNAKAIEK 1511
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1159 ELERLRRENKDIENLRREREHLEME--LEKAEMERSTYVTEVRELKAQL----NETLTKLRTEQNERQKVAGDLHK---- 1228
Cdd:TIGR01612 1512 NKELFEQYKKDVTELLNKYSALAIKnkFAKTKKDSEIIIKEIKDAHKKFileaEKSEQKIKEIKKEKFRIEDDAAKndks 1591
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275  1229 ------AQQSLELIQSKIVKAAgDITVIENsDVSPETESSEKETMSVSLNQTVTQLQQLLQAVN 1286
Cdd:TIGR01612 1592 nkaaidIQLSLENFENKFLKIS-DIKKKIN-DCLKETESIEKKISSFSIDSQDTELKENGDNLN 1653
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
411-641 1.07e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  411 VREQMEAEIAHLKQENGILRDAVSNTTNQLESKQsAELNKLRQDyarlvNELTEKTGKLQQEEVQKKNAEQAVTQLKVQL 490
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEEAE-AALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  491 QEAERRWEEVQSYIRKRTAEHEAAQQDlqskfvakeNEVQSLHSKLtdtlvskQQLEQRLMQLmeseQKRVNKEESlqmQ 570
Cdd:COG3206   236 AEAEARLAALRAQLGSGPDALPELLQS---------PVIQQLRAQL-------AELEAELAEL----SARYTPNHP---D 292
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 383418275  571 VQDILEQNEALKAQIQQFHSQIAAQTSASVlaeelhKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQ 641
Cdd:COG3206   293 VIALRAQIAALRAQLQQEAQRILASLEAEL------EALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
730-1042 1.69e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   730 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKeVQDLKAKQND--QVSFASLVEELKKVIHEKD 807
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER-YQALLKEKREyeGYELLKEKEALERQKEAIE 243
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   808 GKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI----GNVQLE-KAQQLSITSQVQELQNLLKGKEEQMntmkav 882
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRvKEKIGELEAEIASLERSIAEKEREL------ 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   883 lEEKEKDLANTGKWLQDLQEENESLKahvQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKL 962
Cdd:TIGR02169  318 -EDAEERLAKLEAEIDKLLAEIEELE---REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   963 LQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEisgLWNELDSLKDAVEHQRKKNNERQQQVEAVELE 1042
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE---LEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
829-1238 1.81e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 1.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  829 KTVQDLKQEIKALKEEIgnvqlekAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENEslk 908
Cdd:COG4717    64 RKPELNLKELKELEEEL-------KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE--- 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  909 ahvqevaqhnlkevssasqFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQA 988
Cdd:COG4717   134 -------------------LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  989 SSFP-PHEELLKVISEREKEISGLWNELDSLKDAVE-----HQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSY 1062
Cdd:COG4717   195 QDLAeELEELQQRLAELEEELEEAQEELEELEEELEqleneLEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILT 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1063 SE-----------WLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQL---ECEKYKSVLAETEGILQKLQRSV 1128
Cdd:COG4717   275 IAgvlflvlgllaLLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLR 354
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1129 EQEENKWKVKVDESHKTIKQ-MQSSFTSSEQELERLRRENKDIENLRREREHLEMELEKA--EMERSTYVTEVRELKAQL 1205
Cdd:COG4717   355 EAEELEEELQLEELEQEIAAlLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELlgELEELLEALDEEELEEEL 434
                         410       420       430
                  ....*....|....*....|....*....|...
gi 383418275 1206 NETLTKLRTEQNERQKVAGDLHKAQQSLELIQS 1238
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQLEE 467
COG5022 COG5022
Myosin heavy chain [General function prediction only];
730-1293 2.36e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 2.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  730 VEQMEKCIQEKDEKLKTVEELLETG--LIQVAT--KEEELNAIRTENSSLTKEVQDLK-AKQNDQVSFASL--VEELKKV 802
Cdd:COG5022   877 VELAERQLQELKIDVKSISSLKLVNleLESEIIelKKSLSSDLIENLEFKTELIARLKkLLNNIDLEEGPSieYVKLPEL 956
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  803 --IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGnvqlekaqqlSITSQVQELQNLLKGKEEqMNTMK 880
Cdd:COG5022   957 nkLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELA----------ELSKQYGALQESTKQLKE-LPVEV 1025
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  881 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNlKEVSSASQFEELEIVLKEKENELKRVEAMLKE-RESDLSSK 959
Cdd:COG5022  1026 AELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQ-ARYKALKLRRENSLLDDKQLYQLESTENLLKTiNVKDLEVT 1104
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  960 TKLLqdVQDENKLFKSQIEQLKQQNYQQASSFPPheELLKVISEREKEISGLWNELDSLKDAVEHQRK--------KNNE 1031
Cdd:COG5022  1105 NRNL--VKPANVLQFIVAQMIKLNLLQEISKFLS--QLVNTLEPVFQKLSVLQLELDGLFWEANLEALpspppfaaLSEK 1180
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1032 RQQQVEAVELEAK---EVLKKLFPKVSVPSNLSYSEWLHGFEKK--AKECMAGTSGSEevkvlehKLKEADEMHTLLQLE 1106
Cdd:COG5022  1181 RLYQSALYDEKSKlssSEVNDLKNELIALFSKIFSGWPRGDKLKklISEGWVPTEYST-------SLKGFNNLNKKFDTP 1253
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1107 CEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTS---SEQELERLRRENKDIENL-----RRERE 1178
Cdd:COG5022  1254 ASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRtkaSSLRWKSATEVNYNSEELddwcrEFEIS 1333
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1179 HLEMELEkaEMERSTYVTEVRELKAQLNETLTKLRTEQN--ERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVS 1256
Cdd:COG5022  1334 DVDEELE--ELIQAVKVLQLLKDDLNKLDELLDACYSLNpaEIQNLKSRYDPADKENNLPKEILKKIEALLIKQELQLSL 1411
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 383418275 1257 PETES---------SEKETMsVSLNQTVTQLQQLLQAVNQQLTKEK 1293
Cdd:COG5022  1412 EGKDEtevhlseifSEEKSL-ISLDRNSIYKEEVLSSLSALLTKEK 1456
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
320-621 2.74e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 2.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   320 KKSSKGELTTLVHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMSEKERsnvvIARMKDRIGTLEKEHNVFQNKIHVSYQ 399
Cdd:TIGR02169  669 SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK----IGEIEKEIEQLEQEEEKLKERLEELEE 744
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   400 ETQQMQMKFQQVREQM---EAEIAHLKQENGILRDAVSN-----------TTNQLESKQSAE--------------LNKL 451
Cdd:TIGR02169  745 DLSSLEQEIENVKSELkelEARIEELEEDLHKLEEALNDlearlshsripEIQAELSKLEEEvsriearlreieqkLNRL 824
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   452 RQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQ----------SYIRKRTAEHEAAQQDLQSK 521
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEaalrdlesrlGDLKKERDELEAQLRELERK 904
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL------MESEQKRVNKEESLQMQVQDILEQNEALK----AQIQQFHSQ 591
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALEEELSEIedpkgeDEEIPEEELSLEDVQAELQRVEEEIRALEpvnmLAIQEYEEV 984
                          330       340       350
                   ....*....|....*....|....*....|
gi 383418275   592 IAAQTSasvLAEELHKVIAEKDKQIKQTED 621
Cdd:TIGR02169  985 LKRLDE---LKEKRAKLEEERKAILERIEE 1011
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
995-1300 4.50e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 4.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  995 EELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFpkvsvpsnlsysewlhgfekkak 1074
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY----------------------- 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1075 ecmagtSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLqrsvEQEENKWKVKVDESHKTIKQMQSSFT 1154
Cdd:COG1196   292 ------ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL----EEELEELEEELEEAEEELEEAEAELA 361
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1155 SSEQELERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLE 1234
Cdd:COG1196   362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 383418275 1235 LIQSKIVKAAGDItviensdvspETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE 1300
Cdd:COG1196   442 EALEEAAEEEAEL----------EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
377-556 4.78e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 4.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  377 KDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEA-------------------EIAHLKQEngilRDAVSNTT 437
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswdeidvasaerEIAELEAE----LERLDASS 684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  438 NQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYI---RKRTAEHEAA 514
Cdd:COG4913   685 DDLAALE-EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleeRFAAALGDAV 763
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 383418275  515 QQDLQSKFvakENEVQSLHSKLtdtlvskQQLEQRLMQLMES 556
Cdd:COG4913   764 ERELRENL---EERIDALRARL-------NRAEEELERAMRA 795
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
1154-1276 4.95e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 44.69  E-value: 4.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1154 TSSEQELERLRREnkdIENLRREREHLEMELEKAEMERstyVTEVRELKAQLNETLTKLRTE-QNERQKVAGdlhkaqqs 1232
Cdd:COG0542   407 DSKPEELDELERR---LEQLEIEKEALKKEQDEASFER---LAELRDELAELEEELEALKARwEAEKELIEE-------- 472
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 383418275 1233 LELIQSKIVKAAGDITVIENSDVSPETESSEKETMsvsLNQTVT 1276
Cdd:COG0542   473 IQELKEELEQRYGKIPELEKELAELEEELAELAPL---LREEVT 513
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
412-621 5.42e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 5.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  412 REQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY-------ARLVN-ELTEKTGKLQQEEVQKKNAEQAV 483
Cdd:NF012221 1564 KERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETNGQAQrdaileeSRAVTkELTTLAQGLDALDSQATYAGESG 1643
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  484 TQLKVQLqeAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKlTDTLVskQQLEQRLMQLMESEQKRVNK 563
Cdd:NF012221 1644 DQWRNPF--AGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAK-SEAGV--AQGEQNQANAEQDIDDAKAD 1718
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275  564 EESLQMQVqdILEQNEALKAQIQQFHS----QIAAQTSASVLAEELHKVIAEKdKQIKQTED 621
Cdd:NF012221 1719 AEKRKDDA--LAKQNEAQQAESDANAAandaQSRGEQDASAAENKANQAQADA-KGAKQDES 1777
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
512-1031 6.09e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.04  E-value: 6.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   512 EAAQQDLQSKfvakENEVQSLHSKLtDTLVSKQQ-LEQRLMQLMESEQKRVNKEESLQMQVQDI---LEQNEALKAQIQQ 587
Cdd:pfam10174  292 DQLKQELSKK----ESELLALQTKL-ETLTNQNSdCKQHIEVLKESLTAKEQRAAILQTEVDALrlrLEEKESFLNKKTK 366
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   588 FHSQIAAQTSAsvLAEELHKV---IAEKDKQIKQTEDSLANERDHLTSKEEELKDiqnmnflLKAEVQKLQALANEQAAA 664
Cdd:pfam10174  367 QLQDLTEEKST--LAGEIRDLkdmLDVKERKINVLQKKIENLQEQLRDKDKQLAG-------LKERVKSLQTDSSNTDTA 437
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   665 aheLEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQTLVSEQ-----PNKDVVEQMEKCIQE 739
Cdd:pfam10174  438 ---LTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKessliDLKEHASSLASSGLK 514
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   740 KDEKLKTVEelletglIQVATKEEELNAIrtenssltkEVQDLKAKQndqvsfASLVEELKKVIHEKdgkiksveellea 819
Cdd:pfam10174  515 KDSKLKSLE-------IAVEQKKEECSKL---------ENQLKKAHN------AEEAVRTNPEINDR------------- 559
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   820 ellkvankektVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLlkgKEEQMNTMKAVLEEKEKDLANTGKWLQD 899
Cdd:pfam10174  560 -----------IRLLEQEVARYKEESGKAQAEVERLLGILREVENEKND---KDKKIAELESLTLRQMKEQNKKVANIKH 625
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   900 LQEENESLKAHVQEVA---QHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQ 976
Cdd:pfam10174  626 GQQEMKKKGAQLLEEArrrEDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEE 705
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 383418275   977 IEQLKQqnyqqassfpphEELLKVISEREKEISGLwnELDSLKdavehqRKKNNE 1031
Cdd:pfam10174  706 ILEMKQ------------EALLAAISEKDANIALL--ELSSSK------KKKTQE 740
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
920-1293 6.48e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 43.96  E-value: 6.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   920 KEVSSASQFEELEIVLKEKENELKRVEAMLkerESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK 999
Cdd:pfam05557    3 ELIESKARLSQLQNEKKQMELEHKRARIEL---EKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNR 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1000 VISEREKEISGLWNELDSLK-DAVEHQRKKNNE---RQQQVEAVELEAKEVLKKLfpkvsvpsnlsysewlhgfekkakE 1075
Cdd:pfam05557   80 LKKKYLEALNKKLNEKESQLaDAREVISCLKNElseLRRQIQRAELELQSTNSEL------------------------E 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1076 CMagtsgSEEVKVLEHKLKEADEmhtlLQLECEKYKSVLAETEGILQKLQRSVEQEENkWKVKVdeshKTIKQMQSSFTS 1155
Cdd:pfam05557  136 EL-----QERLDLLKAKASEAEQ----LRQNLEKQQSSLAEAEQRIKELEFEIQSQEQ-DSEIV----KNSKSELARIPE 201
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1156 SEQELERLRRENKDIENLRREREHLEMELE--KAEMERstyVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSL 1233
Cdd:pfam05557  202 LEKELERLREHNKHLNENIENKLLLKEEVEdlKRKLER---EEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSP 278
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1234 ELIQSKIVKaagditvIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEK 1293
Cdd:pfam05557  279 EDLSRRIEQ-------LQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLKKIEDLN 331
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1089-1235 6.65e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 6.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1089 LEHKLKEADEmhtlLQLECEKYKSVLAETEGILQKLQRsvEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENK 1168
Cdd:COG4913   612 LAALEAELAE----LEEELAEAEERLEALEAELDALQE--RREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSD 685
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 383418275 1169 DIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQnERQKVAGDLHKAQQSLEL 1235
Cdd:COG4913   686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ-DRLEAAEDLARLELRALL 751
mukB PRK04863
chromosome partition protein MukB;
468-638 7.83e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 7.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  468 KLQQEEVQKKNAEQaVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSkfvakENEVQSLHskltdtlvskQQLE 547
Cdd:PRK04863  501 LLRRLREQRHLAEQ-LQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDD-----EDELEQLQ----------EELE 564
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  548 QRLMQLmeSEQKRVNKEEslQMQVQDILEQneaLKAQIQQFHSQ----IAAQTSASVLAEELHKVIAEK---DKQIKQT- 619
Cdd:PRK04863  565 ARLESL--SESVSEARER--RMALRQQLEQ---LQARIQRLAARapawLAAQDALARLREQSGEEFEDSqdvTEYMQQLl 637
                         170       180
                  ....*....|....*....|.
gi 383418275  620 --EDSLANERDHLTSKEEELK 638
Cdd:PRK04863  638 erERELTVERDELAARKQALD 658
PRK00106 PRK00106
ribonuclease Y;
825-967 8.08e-04

ribonuclease Y;


Pssm-ID: 178867 [Multi-domain]  Cd Length: 535  Bit Score: 43.70  E-value: 8.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  825 ANKEKTVQDLKQEIKALKEEIGNVQLEKAQQL-SITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEE 903
Cdd:PRK00106   68 ALKKELLLEAKEEARKYREEIEQEFKSERQELkQIESRLTERATSLDRKDENLSSKEKTLESKEQSLTDKSKHIDEREEQ 147
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 383418275  904 NESLkahvQEVAQHNLKEVSSASQFEELEIVLKEKENEL--------KRVEAMLKEReSDLSSKTKLLQDVQ 967
Cdd:PRK00106  148 VEKL----EEQKKAELERVAALSQAEAREIILAETENKLtheiatriREAEREVKDR-SDKMAKDLLAQAMQ 214
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
799-1293 8.15e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 8.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNvqlEKAQQLSITSQVQELQNLLKGKEEQMNT 878
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKK---NKDKINKLNSDLSKINSEIKNDKEQKNK 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   879 MKAVLEEKEKDLANTGKWLQDLQEENESLKahvQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSS 958
Cdd:TIGR04523  122 LEVELNKLEKQKKENKKNIDKFLTEIKKKE---KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLK 198
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   959 KTKLLQDVQ---DENKLFKSQIEQLKQQNYQQASSFpphEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQ 1035
Cdd:TIGR04523  199 LELLLSNLKkkiQKNKSLESQISELKKQNNQLKDNI---EKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE 275
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1036 VEavelEAKEVLKKLfpkvsvpsnlsysewlhgfekkakecmagtsgSEEVKVLEHKLKEademhtllqLECEKYKSVLA 1115
Cdd:TIGR04523  276 LE----QNNKKIKEL--------------------------------EKQLNQLKSEISD---------LNNQKEQDWNK 310
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1116 ETEGILQKLQRSVEQEENKwkvkVDESHKTIKQMQSSFTSSEQELERLRRENKDIenlRREREHLEMELEKAEMERSTYV 1195
Cdd:TIGR04523  311 ELKSELKNQEKKLEEIQNQ----ISQNNKIISQLNEQISQLKKELTNSESENSEK---QRELEEKQNEIEKLKKENQSYK 383
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1196 TEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTV 1275
Cdd:TIGR04523  384 QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTR 463
                          490
                   ....*....|....*...
gi 383418275  1276 TQLQQLLQAVNQQLTKEK 1293
Cdd:TIGR04523  464 ESLETQLKVLSRSINKIK 481
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
885-1294 8.90e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 8.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  885 EKEKDLANTgkwLQDLQEENESLKAHVQEVAQHNLKEvssasqfEELEIVLKEKENELKRVEAMLKEREsdlssktKLLQ 964
Cdd:COG3096   289 ELRRELFGA---RRQLAEEQYRLVEMARELEELSARE-------SDLEQDYQAASDHLNLVQTALRQQE-------KIER 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  965 DVQDENKLfksqIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVElEAK 1044
Cdd:COG3096   352 YQEDLEEL----TERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALE-KAR 426
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1045 EVLKKlfPKVSvPSNLSysEWLHGFEKKAKEcmagtsGSEEVKVLEHKLKEADEMHTllqleceKYKSVLAETEGILQKL 1124
Cdd:COG3096   427 ALCGL--PDLT-PENAE--DYLAAFRAKEQQ------ATEEVLELEQKLSVADAARR-------QFEKAYELVCKIAGEV 488
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1125 QRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKDIENLRRE-----------REHLEMELEKAEMER-- 1191
Cdd:COG3096   489 ERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEfcqrigqqldaAEELEELLAELEAQLee 568
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1192 -STYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKivkaagditviensdvspetesseketmsvs 1270
Cdd:COG3096   569 lEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQ------------------------------- 617
                         410       420
                  ....*....|....*....|....
gi 383418275 1271 LNQTVTQLQQLLQAVNQQLTKEKE 1294
Cdd:COG3096   618 SGEALADSQEVTAAMQQLLERERE 641
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
731-1023 9.05e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 43.76  E-value: 9.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  731 EQMEK--CIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN-SSLTKEVQDLKAKQNDQVSFASLVEELKKVIhekd 807
Cdd:PRK05771    4 VRMKKvlIVTLKSYKDEVLEALHELGVVHIEDLKEELSNERLRKlRSLLTKLSEALDKLRSYLPKLNPLREEKKKV---- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  808 gKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKeeqmnTMKAVLEEKE 887
Cdd:PRK05771   80 -SVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDLSLLLGFK-----YVSVFVGTVP 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  888 KDlantgkwlQDLQEENESLKAHVQEVAQHNLKE----VSSASQFEELEIVLkeKENELKRVEAmlkereSDLSSKTKLL 963
Cdd:PRK05771  154 ED--------KLEELKLESDVENVEYISTDKGYVyvvvVVLKELSDEVEEEL--KKLGFERLEL------EEEGTPSELI 217
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  964 QDVQDENKLFKSQIEQLKqqnyqqassfpphEELLKVISEREKEISGLWNELDSLKDAVE 1023
Cdd:PRK05771  218 REIKEELEEIEKERESLL-------------EELKELAKKYLEELLALYEYLEIELERAE 264
PTZ00121 PTZ00121
MAEBL; Provisional
667-1294 9.30e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 9.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  667 ELEKMQQSVYVKDDK----IRLLEEQLQHEISNKMEEFKILNDQNKALklEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE 742
Cdd:PTZ00121 1138 DARKAEEARKAEDAKrveiARKAEDARKAEEARKAEDAKKAEAARKAE--EVRKAEELRKAEDARKAEAARKAEEERKAE 1215
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  743 KLKTVEELLETGLIQVA--TKEEELNAIRTENSSLTKEVQdlKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Cdd:PTZ00121 1216 EARKAEDAKKAEAVKKAeeAKKDAEEAKKAEEERNNEEIR--KFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD 1293
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  821 LLKVANKEKTVQDLKQeiKALKEEIGNVQLEKAQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 900
Cdd:PTZ00121 1294 EAKKAEEKKKADEAKK--KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  901 QEENESLKAhvqEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKERESdlssKTKLLQDVQDENKLFKSQIEQL 980
Cdd:PTZ00121 1372 KKEEAKKKA---DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE----AKKKAEEKKKADEAKKKAEEAK 1444
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  981 KQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQqveAVELEAKEVLKKLFPKVSVPSNL 1060
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKK---ADEAKKAAEAKKKADEAKKAEEA 1521
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1061 SYSEWLHGFEKKAKECMAgtSGSEEVKVLEhKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVD 1140
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEA--KKAEEKKKAD-ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1141 ESHKTIKQMQSSFTSSEQELERLRRENKDIENLRREREhlemELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQ 1220
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVE----QLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275 1221 KVAGDLHKAQQSLELIQSKIVKAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1294
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
COG4487 COG4487
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];
863-1052 1.08e-03

Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];


Pssm-ID: 443580 [Multi-domain]  Cd Length: 425  Bit Score: 43.01  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-----GKWLQDLQEENESLKAHVQEVAQHNLKEVssASQFEELEIVLKE 937
Cdd:COG4487    29 AEFEKELAERLADAAKREAALELAEAKAKAQlqeqvAEKDAEIAELRARLEAEERKKALAVAEEK--EKELAALQEALAE 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  938 KENEL-----KRVEAMLKERESDLSSKTKLLQ---DVQDENKLFKSQIEQLKQQNYQQASSfppheelLKViSEREKEIS 1009
Cdd:COG4487   107 KDAKLaelqaKELELLKKERELEDAKREAELTvekERDEELDELKEKLKKEEEEKQLAEKS-------LKV-AEYEKQLK 178
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 383418275 1010 GLWNELDSLKDAVEHQrkknnERQQQVEAVELEAKEVLKKLFP 1052
Cdd:COG4487   179 DMQEQIEELKRKKEQG-----STQLQGEVLELEFEELLATAFP 216
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
482-1222 1.30e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.42  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   482 AVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKfvAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRV 561
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKL--KEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   562 NKEESLQMQVQDILEQNealkaQIQQFHSQIAAQTSASVLAEElhKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQ 641
Cdd:pfam02463  241 LLQELLRDEQEEIESSK-----QEIEKEEEKLAQVLKENKEEE--KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   642 NMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVK---DDKIRLLEEQLQHEISNKMEEFKILNDQNKALKLEVQKLQ 718
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKreaEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   719 TLVSEQPNKDVVEQMEKcIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEE 798
Cdd:pfam02463  394 EEELELKSEEEKEAQLL-LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSED 472
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQ----LSITSQVQELQNLLKGKEE 874
Cdd:pfam02463  473 LLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGrlgdLGVAVENYKVAISTAVIVE 552
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   875 QMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEVSSASQFEELEIVLKEKENELKRVEAMLKER-- 952
Cdd:pfam02463  553 VSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKdt 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   953 -----------------------ESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEIS 1009
Cdd:pfam02463  633 eltklkesakakesglrkgvsleEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1010 GLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYsewlhgfEKKAKECMAGTSGSEEVKVL 1089
Cdd:pfam02463  713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE-------KSELSLKEKELAEEREKTEK 785
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  1090 EHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRRENKD 1169
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITK 865
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 383418275  1170 IENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKV 1222
Cdd:pfam02463  866 EELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE 918
PRK01156 PRK01156
chromosome segregation protein; Provisional
774-1282 1.41e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  774 SLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIK---ALKEEIGNVQL 850
Cdd:PRK01156  177 MLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNelsSLEDMKNRYES 256
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  851 EKAQQLSITSQVQELQNLLKGKEEQMN--TMKAVLEEKEK--DLANTGKWLQDLQEENESLKAHVQEVaQHNLKEVSSAS 926
Cdd:PRK01156  257 EIKTAESDLSMELEKNNYYKELEERHMkiINDPVYKNRNYinDYFKYKNDIENKKQILSNIDAEINKY-HAIIKKLSVLQ 335
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  927 QFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLFKSQIEQLKQQNYQQAS-SFPPHEELLKVISERE 1005
Cdd:PRK01156  336 KDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKiQEIDPDAIKKELNEIN 415
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1006 KEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVL--KKLFPKVSVPSNLSYSEWLHGFEKKAKECMAGTSGS 1083
Cdd:PRK01156  416 VKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDI 495
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1084 EEVKVLEHKLKEADEMHTLLQLECE--KYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELE 1161
Cdd:PRK01156  496 DEKIVDLKKRKEYLESEEINKSINEynKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALA 575
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1162 RlrRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIV 1241
Cdd:PRK01156  576 V--ISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKID 653
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 383418275 1242 KAAGDITVIENSDVSPETESSEKETMSVSLNQTVTQLQQLL 1282
Cdd:PRK01156  654 NYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAK 694
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-532 1.42e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  412 REQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA-------EQAVT 484
Cdd:COG4913   304 LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALglplpasAEEFA 383
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 383418275  485 QLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSL 532
Cdd:COG4913   384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
737-915 1.44e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  737 IQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQvsfASLVEELKKVIHEKDGKIKSVEel 816
Cdd:COG1579    12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRL---ELEIEEVEARIKKYEEQLGNVR-- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  817 leaellkvanKEKTVQDLKQEIKALKEEIGnvQLEKaQQLSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTgkw 896
Cdd:COG1579    87 ----------NNKEYEALQKEIESLKRRIS--DLED-EILELMERIEELEEELAELEAELAELEAELEEKKAELDEE--- 150
                         170
                  ....*....|....*....
gi 383418275  897 LQDLQEENESLKAHVQEVA 915
Cdd:COG1579   151 LAELEAELEELEAEREELA 169
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
561-988 2.50e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  561 VNKEESLQMQVQDILEQNEALKAQIQQF-HSQIAAQTSASvlAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKD 639
Cdd:COG4717    15 RDRTIEFSPGLNVIYGPNEAGKSTLLAFiRAMLLERLEKE--ADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAE 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  640 IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQsVYVKDDKIRLLEEQLQH------EISNKMEEFKILNDQNKALKLE 713
Cdd:COG4717    93 LQEELEELEEELEELEAELEELREELEKLEKLLQ-LLPLYQELEALEAELAElperleELEERLEELRELEEELEELEAE 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  714 VQKLQTLVSEQPNkDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQ---- 789
Cdd:COG4717   172 LAELQEELEELLE-QLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKearl 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  790 --------VSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSIT-- 859
Cdd:COG4717   251 llliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALgl 330
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  860 -------------SQVQELQNLLKGKEEQMNTMKAVLEEKEK-------------DLANTGKWLQDLQEENESLKAHVQE 913
Cdd:COG4717   331 ppdlspeellellDRIEELQELLREAEELEEELQLEELEQEIaallaeagvedeeELRAALEQAEEYQELKEELEELEEQ 410
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 383418275  914 VAQHN--LKEVSSASQFEELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQDENKLF--KSQIEQLKQQNYQQA 988
Cdd:COG4717   411 LEELLgeLEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAelLQELEELKAELRELA 489
PLN02939 PLN02939
transferase, transferring glycosyl groups
468-801 2.86e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.20  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  468 KLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLhsKLTDTLVSKQQLE 547
Cdd:PLN02939   64 KLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDF--QLEDLVGMIQNAE 141
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  548 QRLMQLmesEQKRVNKEEslqmQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA--EELHKVIAEK--DKQIKQTEDSL 623
Cdd:PLN02939  142 KNILLL---NQARLQALE----DLEKILTEKEALQGKINILEMRLSETDARIKLAaqEKIHVEILEEqlEKLRNELLIRG 214
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  624 ANERDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLqheISNKMEEFKIL 703
Cdd:PLN02939  215 ATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKF---IVAQEDVSKLS 291
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  704 NDQNKALKLEVQKLQTLVSEQPNKdvVEQMEKCIQEKDEKLKTVEELLET--------------GLIQVATK--EEELNA 767
Cdd:PLN02939  292 PLQYDCWWEKVENLQDLLDRATNQ--VEKAALVLDQNQDLRDKVDKLEASlkeanvskfssykvELLQQKLKllEERLQA 369
                         330       340       350
                  ....*....|....*....|....*....|....
gi 383418275  768 IRTENSSLTKEVQDLKAKQNDQVSfaSLVEELKK 801
Cdd:PLN02939  370 SDHEIHSYIQLYQESIKEFQDTLS--KLKEESKK 401
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
668-1234 3.02e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 3.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEfKILNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTV 747
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLES-ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEI 260
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  748 EELLETgliqVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLveelkkviheKDGKIKSVEELLEAELLKVANK 827
Cdd:PRK02224  261 EDLRET----IAETEREREELAEEVRDLRERLEELEEERDDLLAEAGL----------DDADAEAVEARREELEDRDEEL 326
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  828 EKTVQDLKQEIKALKEEIGnvqlekaqqlSITSQVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAE----------SLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL 396
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  908 KAHVQEvaqhnlkevsSASQFEELEIVLKEKENELKRVEAMLKERESDLSSktklLQDVQDENKLFksqIEQLKQQNYQQ 987
Cdd:PRK02224  397 RERFGD----------APVDLGNAEDFLEELREERDELREREAELEATLRT----ARERVEEAEAL---LEAGKCPECGQ 459
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  988 ASSFPPHEEllkVISEREKEISGLWNELDSLKDAVEHQRKKNNerqQQVEAVELEAKevLKKLFPKVSVPSNLsYSEWLH 1067
Cdd:PRK02224  460 PVEGSPHVE---TIEEDRERVEELEAELEDLEEEVEEVEERLE---RAEDLVEAEDR--IERLEERREDLEEL-IAERRE 530
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1068 GFEKKAKECmagTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEEnkwkvkvdeshkTIK 1147
Cdd:PRK02224  531 TIEEKRERA---EELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE------------RIR 595
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1148 QMQSSFTSSEQELERLRRENKDIENLRRE-REHLEMELE-KAEMERS---TYVTEVRELK-------AQLNETLTKLRTE 1215
Cdd:PRK02224  596 TLLAAIADAEDEIERLREKREALAELNDErRERLAEKRErKRELEAEfdeARIEEAREDKeraeeylEQVEEKLDELREE 675
                         570
                  ....*....|....*....
gi 383418275 1216 QNERQKVAGDLHKAQQSLE 1234
Cdd:PRK02224  676 RDDLQAEIGAVENELEELE 694
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
570-948 3.34e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 3.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   570 QVQDILEQNEALKAQIQQFHSQI-AAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQNMNFLLK 648
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIeNRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   649 AEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLleEQLQHEISNKMEEFK----ILNDQNKALKLEVQKLQTLVSEQ 724
Cdd:TIGR02169  758 SELKELEARIEELEEDLHKLEEALNDLEARLSHSRI--PEIQAELSKLEEEVSrieaRLREIEQKLNRLTLEKEYLEKEI 835
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   725 PNKdvVEQMEKCIQEKDEKLKTVEELLetglIQVATKEEELNAIRTENSSLTKEVQDLKAKqndqvsfaslVEELKKVIH 804
Cdd:TIGR02169  836 QEL--QEQRIDLKEQIKSIEKEIENLN----GKKEELEEELEELEAALRDLESRLGDLKKE----------RDELEAQLR 899
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   805 EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSQVQELQNLlkgkEEQMNTMKAV-- 882
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRV----EEEIRALEPVnm 975
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   883 -----LEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQ--------------HNLKEV------SSASQFEE------- 930
Cdd:TIGR02169  976 laiqeYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKkkrevfmeafeainENFNEIfaelsgGTGELILEnpddpfa 1055
                          410       420
                   ....*....|....*....|
gi 383418275   931 --LEIVLKEKENELKRVEAM 948
Cdd:TIGR02169 1056 ggLELSAKPKGKPVQRLEAM 1075
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
409-790 4.39e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  409 QQVREQMEAEIAHLKQENGILRDAVSNTTNQLEskqsaeLNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKV 488
Cdd:COG4717    94 QEELEELEEELEELEAELEELREELEKLEKLLQ------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEE 167
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  489 QLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLmESEQKRVNKEESLQ 568
Cdd:COG4717   168 LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL-ENELEAAALEERLK 246
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  569 MQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLAN-ERDHLTSKEEELKDIQNMNFLL 647
Cdd:COG4717   247 EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEaEELQALPALEELEEEELEELLA 326
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN------------------KMEEFKILNDQNKA 709
Cdd:COG4717   327 ALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllaeagvedeeelraaleQAEEYQELKEELEE 406
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  710 LKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN--SSLTKEVQDLKAKQN 787
Cdd:COG4717   407 LEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGelAELLQELEELKAELR 486

                  ...
gi 383418275  788 DQV 790
Cdd:COG4717   487 ELA 489
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
431-641 4.52e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 4.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  431 DAVSNTTNQLESKQsAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRtae 510
Cdd:COG3883    16 PQIQAKQKELSELQ-AELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER--- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  511 heAAQQDLQSKFVAKENEVqsLHSKLTDTLVSKQQLeqrLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQfhs 590
Cdd:COG3883    92 --ARALYRSGGSVSYLDVL--LGSESFSDFLDRLSA---LSKIADADADLLEELKADKAELEAKKAELEAKLAELEA--- 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 383418275  591 qiaAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTSKEEELKDIQ 641
Cdd:COG3883   162 ---LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
1089-1242 5.12e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1089 LEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRsvEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRREnk 1168
Cdd:COG1579    22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEK--EIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKE-- 97
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 383418275 1169 dIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVK 1242
Cdd:COG1579    98 -IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1001-1244 6.05e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 6.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1001 ISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLfpkvsvpsnlsysewlhgfekkakecmagT 1080
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-----------------------------R 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1081 SGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAEtegILQKLQRSVEQEENKWKVKVDESHKTIKQ---MQSSFTSSE 1157
Cdd:COG4942    73 ALEQELAALEAELAELEKEIAELRAELEAQKEELAE---LLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARR 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1158 QELERLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQ 1237
Cdd:COG4942   150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229

                  ....*..
gi 383418275 1238 SKIVKAA 1244
Cdd:COG4942   230 ARLEAEA 236
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
479-594 6.70e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 40.42  E-value: 6.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  479 AEQAVTQLKVQLQEAERRWEEVQSYI--RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES 556
Cdd:COG1566    81 LQAALAQAEAQLAAAEAQLARLEAELgaEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAA 160
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 383418275  557 EQKRVNKEESLQMQVQDILEQNE--ALKAQIQQFHSQIAA 594
Cdd:COG1566   161 QAQLEAAQAQLAQAQAGLREEEElaAAQAQVAQAEAALAQ 200
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
554-859 7.41e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.61  E-value: 7.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  554 MESEQKR-VNKEESLQMQVQDILEQNEALKAQIQQfHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANERDHLTS 632
Cdd:PLN03229  413 VDPERKVnMKKREAVKTPVRELEGEVEKLKEQILK-AKESSSKPSELALNEMIEKLKKEIDLEYTEAVIAMGLQERLENL 491
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  633 KEEELK---DIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR---LLE-----EQLQHEISNKMEEFK 701
Cdd:PLN03229  492 REEFSKansQDQLMHPVLMEKIEKLKDEFNKRLSRAPNYLSLKYKLDMLNEFSRakaLSEkkskaEKLKAEINKKFKEVM 571
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  702 I---LNDQNKALKLEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELnAIRTENSSLTKE 778
Cdd:PLN03229  572 DrpeIKEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDT-AEQTPPPNLQEK 650
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  779 VQDLKAKQNDQVSFASLVEELKKVIHEkdgkiKSVEELLEAELLKVANKEKtVQDLKQEIK----------ALKEEIGNV 848
Cdd:PLN03229  651 IESLNEEINKKIERVIRSSDLKSKIEL-----LKLEVAKASKTPDVTEKEK-IEALEQQIKqkiaealnssELKEKFEEL 724
                         330
                  ....*....|.
gi 383418275  849 QLEKAQQLSIT 859
Cdd:PLN03229  725 EAELAAARETA 735
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
269-526 7.68e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 40.87  E-value: 7.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   269 KKLKTETDKENA-----EVKFKDFLLSLKTMMFSEDEAL-CVVDLLKEKSGVIQDAlkKSSKGELTTLVHQLQEKDKLLA 342
Cdd:pfam15921  607 QEFKILKDKKDAkirelEARVSDLELEKVKLVNAGSERLrAVKDIKQERDQLLNEV--KTSRNELNSLSEDYEVLKRNFR 684
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   343 AVKEDAAATKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMeaeiAHL 422
Cdd:pfam15921  685 NKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM----TNA 760
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275   423 KQENGILRDavsnttnqleskqsaELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQS 502
Cdd:pfam15921  761 NKEKHFLKE---------------EKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
                          250       260
                   ....*....|....*....|....
gi 383418275   503 YIRKRtaEHEAAQQDLQSKFVAKE 526
Cdd:pfam15921  826 IIQRQ--EQESVRLKLQHTLDVKE 847
PRK11281 PRK11281
mechanosensitive channel MscK;
830-1037 8.05e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 40.67  E-value: 8.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  830 TVQDLKQEIKALKEEignvQLEKAQQLSITSQVQELQNLLKGKEEQmntmKAVLEEKEKDLANTGKWLQDLQEENESLKA 909
Cdd:PRK11281   37 TEADVQAQLDALNKQ----KLLEAEDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALKD 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  910 HVQEVAQHNLKEVSSAsqfeELEIVLKEKENELKRVEAMLKERESDLSSKTKLLQDVQ---DENKLFKSQIE-QLKQQNY 985
Cdd:PRK11281  109 DNDEETRETLSTLSLR----QLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQaalYANSQRLQQIRnLLKGGKV 184
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  986 QQASSFPPHEELLKV--------ISEREKEISGlwNELdsLKDAVEHQRKKNNERQQQVE 1037
Cdd:PRK11281  185 GGKALRPSQRVLLQAeqallnaqNDLQRKSLEG--NTQ--LQDLLQKQRDYLTARIQRLE 240
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
874-1189 8.07e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 40.30  E-value: 8.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  874 EQMNTMKAVLEEKEKDlantgKWLQDLQEENEslkAHVQEvaqhnLKEVSSASQFEELE---IVLKEKENELKRVEAMLK 950
Cdd:PRK05771    4 VRMKKVLIVTLKSYKD-----EVLEALHELGV---VHIED-----LKEELSNERLRKLRsllTKLSEALDKLRSYLPKLN 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  951 eresdLSSKTKLLQDVQDENKLFKSQIEQLkqqnyqqassfpphEELLKVISEREKEISGLWNELDSLKDavehqrkknn 1030
Cdd:PRK05771   71 -----PLREEKKKVSVKSLEELIKDVEEEL--------------EKIEKEIKELEEEISELENEIKELEQ---------- 121
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1031 erqqqveavELEAKEVLKKLfpkvSVP-SNLSYSEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLeceK 1109
Cdd:PRK05771  122 ---------EIERLEPWGNF----DLDlSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVYVVVV---V 185
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275 1110 YKSVLAETEGILQKLqrSVEQEENKWKVKVDESHKTIKQMQSSFtssEQELERLRRE-----NKDIENLRREREHLEMEL 1184
Cdd:PRK05771  186 LKELSDEVEEELKKL--GFERLELEEEGTPSELIREIKEELEEI---EKERESLLEElkelaKKYLEELLALYEYLEIEL 260

                  ....*
gi 383418275 1185 EKAEM 1189
Cdd:PRK05771  261 ERAEA 265
46 PHA02562
endonuclease subunit; Provisional
404-639 9.21e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 40.38  E-value: 9.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  404 MQMKFQQVREQME--AEIAHLKQENGILRDAVSNTTNQLESkQSAELNKLRQD---YARLVNELTEKTGKLQQEEVQK-- 476
Cdd:PHA02562  145 MQLSAPARRKLVEdlLDISVLSEMDKLNKDKIRELNQQIQT-LDMKIDHIQQQiktYNKNIEEQRKKNGENIARKQNKyd 223
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  477 ------KNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQS-----KFVAKENE----VQSLH------SK 535
Cdd:PHA02562  224 elveeaKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQfqkviKMYEKGGVcptcTQQISegpdriTK 303
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383418275  536 LTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA--------AQTSASVLAEELHK 607
Cdd:PHA02562  304 IKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKkvkaaieeLQAEFVDNAEELAK 383
                         250       260       270
                  ....*....|....*....|....*....|..
gi 383418275  608 VIAEKDKqIKQTEDSLANERDHLTSKEEELKD 639
Cdd:PHA02562  384 LQDELDK-IVKTKSELVKEKYHRGIVTDLLKD 414
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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