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Conserved domains on  [gi|332660031|gb|AEE85431|]
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tetraspanin7 [Arabidopsis thaliana]

Protein Classification

tetraspanin family protein( domain architecture ID 11992908)

tetraspanin family protein is a transmembrane (TM) glycoprotein with four TM segments that facilitates the interaction of membrane and intracellular signaling molecules (such as integrins, pro-growth factors and their receptors, protein kinase-C) in the formation of membrane signaling microdomains (also referred to as the tetraspanin web)

Gene Ontology:  GO:0016020
PubMed:  15763890|11756464|19709882|16024509|32974937
SCOP:  4001512

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tetraspanin pfam00335
Tetraspanin family;
5-253 2.39e-22

Tetraspanin family;


:

Pssm-ID: 459767  Cd Length: 183  Bit Score: 90.84  E-value: 2.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031    5 SNNLLGILNFFTFLLSIPILSAGIWLGKN------AATECERFLDKPMVVLGIFLMFVSIAGLVGACCRVSCLLWLYLFA 78
Cdd:pfam00335   1 LKYLLFLFNLLFWLLGLLLLGVGVWLLSAfsllllGLSEASAYIPILLIVLGAVIFLVGFLGCCGALKENRCLLLTYFVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031   79 MFLLILLGFCFTIFAFAVTNRGAGevisdrgykeyhvaDYSNWLQKRVNNA-KNWERIRSClmysdvcstyrtryasinv 157
Cdd:pfam00335  81 LLLLFLAELAAGILAFVYRDKLSG--------------LLSNWLKKSLEDGyRDWLDLYSC------------------- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031  158 edfYKSNLNALQS--GCCKpsndcnftyvnpttwtktpgpyknedcnvwdnkpgtlcydceACKAGLLDNIKNSWKKVAK 235
Cdd:pfam00335 128 ---LNSALDSLQSefGCCG------------------------------------------GCKEKLLEWLRKNLKIIGA 162

                         250       260
                  ....*....|....*....|.
gi 332660031  236 VNI---VFLIFLIIVYSVGCC 253
Cdd:pfam00335 163 GVIalgVIQLLGIILACCLCC 183
 
Name Accession Description Interval E-value
Tetraspanin pfam00335
Tetraspanin family;
5-253 2.39e-22

Tetraspanin family;


Pssm-ID: 459767  Cd Length: 183  Bit Score: 90.84  E-value: 2.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031    5 SNNLLGILNFFTFLLSIPILSAGIWLGKN------AATECERFLDKPMVVLGIFLMFVSIAGLVGACCRVSCLLWLYLFA 78
Cdd:pfam00335   1 LKYLLFLFNLLFWLLGLLLLGVGVWLLSAfsllllGLSEASAYIPILLIVLGAVIFLVGFLGCCGALKENRCLLLTYFVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031   79 MFLLILLGFCFTIFAFAVTNRGAGevisdrgykeyhvaDYSNWLQKRVNNA-KNWERIRSClmysdvcstyrtryasinv 157
Cdd:pfam00335  81 LLLLFLAELAAGILAFVYRDKLSG--------------LLSNWLKKSLEDGyRDWLDLYSC------------------- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031  158 edfYKSNLNALQS--GCCKpsndcnftyvnpttwtktpgpyknedcnvwdnkpgtlcydceACKAGLLDNIKNSWKKVAK 235
Cdd:pfam00335 128 ---LNSALDSLQSefGCCG------------------------------------------GCKEKLLEWLRKNLKIIGA 162

                         250       260
                  ....*....|....*....|.
gi 332660031  236 VNI---VFLIFLIIVYSVGCC 253
Cdd:pfam00335 163 GVIalgVIQLLGIILACCLCC 183
 
Name Accession Description Interval E-value
Tetraspanin pfam00335
Tetraspanin family;
5-253 2.39e-22

Tetraspanin family;


Pssm-ID: 459767  Cd Length: 183  Bit Score: 90.84  E-value: 2.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031    5 SNNLLGILNFFTFLLSIPILSAGIWLGKN------AATECERFLDKPMVVLGIFLMFVSIAGLVGACCRVSCLLWLYLFA 78
Cdd:pfam00335   1 LKYLLFLFNLLFWLLGLLLLGVGVWLLSAfsllllGLSEASAYIPILLIVLGAVIFLVGFLGCCGALKENRCLLLTYFVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031   79 MFLLILLGFCFTIFAFAVTNRGAGevisdrgykeyhvaDYSNWLQKRVNNA-KNWERIRSClmysdvcstyrtryasinv 157
Cdd:pfam00335  81 LLLLFLAELAAGILAFVYRDKLSG--------------LLSNWLKKSLEDGyRDWLDLYSC------------------- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332660031  158 edfYKSNLNALQS--GCCKpsndcnftyvnpttwtktpgpyknedcnvwdnkpgtlcydceACKAGLLDNIKNSWKKVAK 235
Cdd:pfam00335 128 ---LNSALDSLQSefGCCG------------------------------------------GCKEKLLEWLRKNLKIIGA 162

                         250       260
                  ....*....|....*....|.
gi 332660031  236 VNI---VFLIFLIIVYSVGCC 253
Cdd:pfam00335 163 GVIalgVIQLLGIILACCLCC 183
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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