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Conserved domains on  [gi|281376614|gb|ADA66099|]
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nicotinamide mononucleotide transporter (plasmid) [Lactococcus lactis subsp. lactis KF147]

Protein Classification

nicotinamide riboside transporter PnuC( domain architecture ID 10007048)

nicotinamide riboside transporter PnuC is involved in the transport of nicotinamide ribonucleoside across the inner membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PnuC COG3201
Nicotinamide riboside transporter PnuC [Coenzyme transport and metabolism];
48-245 5.55e-21

Nicotinamide riboside transporter PnuC [Coenzyme transport and metabolism];


:

Pssm-ID: 442434  Cd Length: 203  Bit Score: 87.23  E-value: 5.55e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  48 FLFTKDASVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKELRAt 127
Cdd:COG3201   10 TLGGTPMSWLELIAVLFGLLSVWLAARRNIWNWPFGIISTLLYAYLFFQAKLYGDALLQVYYFIMSIYGWYQWKRGRDN- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614 128 tKHEVQSKKLTTFQALIYFVGTILLYFMIVIISKKL-GGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIII 206
Cdd:COG3201   89 -EGEVPVRRLSLKEWLLLIAAGVLGTLLLGYLLKAFtDSAVPYLDAFTTVLSLVAQWLMARKYVENWLLWIVVDIVSVPL 167
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 281376614 207 WYnqfmvngTSISLSMLMLQIVMFLNSIYGSIIWLKKSK 245
Cdd:COG3201  168 YF-------YKGLYLTAILYAVFLVLAIYGYRNWRKSAK 199
 
Name Accession Description Interval E-value
PnuC COG3201
Nicotinamide riboside transporter PnuC [Coenzyme transport and metabolism];
48-245 5.55e-21

Nicotinamide riboside transporter PnuC [Coenzyme transport and metabolism];


Pssm-ID: 442434  Cd Length: 203  Bit Score: 87.23  E-value: 5.55e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  48 FLFTKDASVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKELRAt 127
Cdd:COG3201   10 TLGGTPMSWLELIAVLFGLLSVWLAARRNIWNWPFGIISTLLYAYLFFQAKLYGDALLQVYYFIMSIYGWYQWKRGRDN- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614 128 tKHEVQSKKLTTFQALIYFVGTILLYFMIVIISKKL-GGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIII 206
Cdd:COG3201   89 -EGEVPVRRLSLKEWLLLIAAGVLGTLLLGYLLKAFtDSAVPYLDAFTTVLSLVAQWLMARKYVENWLLWIVVDIVSVPL 167
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 281376614 207 WYnqfmvngTSISLSMLMLQIVMFLNSIYGSIIWLKKSK 245
Cdd:COG3201  168 YF-------YKGLYLTAILYAVFLVLAIYGYRNWRKSAK 199
NMN_trans_PnuC TIGR01528
nicotinamide mononucleotide transporter PnuC; The PnuC protein of E. coli is membrane protein ...
55-245 1.28e-20

nicotinamide mononucleotide transporter PnuC; The PnuC protein of E. coli is membrane protein responsible for nicotinamide mononucleotide transport, subject to regulation by interaction with the NadR (also called NadI) protein (see TIGR01526). This model defines a region corresponding to most of the length of PnuC, found primarily in pathogens. The extreme N- and C-terminal regions are poorly conserved and not included in the alignment and model. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]


Pssm-ID: 273672  Cd Length: 189  Bit Score: 85.93  E-value: 1.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614   55 SVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKEL-RATTKHEVQ 133
Cdd:TIGR01528   2 SIIELIAGLMGILCVVLASEGKVSNYIFGLISAVIYLYIAYQTGLYAEVLLQLFFVIANIYGLFAWKKNSqQEENGVTSG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  134 SKKLTTFQALIYFVGTILLYFMIVIISKKLGGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIIIWYNQFmv 213
Cdd:TIGR01528  82 LKKLKGKGWTIILSTSVVLTVVIALILKFIGDNFPWLDSITFVIGIVAQILMVRRYRENWILWLLSNVVSIILWFLAF-- 159
                         170       180       190
                  ....*....|....*....|....*....|..
gi 281376614  214 ngtSISLSMLMLQIVMFLNSIYGSIIWLKKSK 245
Cdd:TIGR01528 160 ---TGSLAMLLTYIIYLFNSLYGFYNWNKSKK 188
NMN_transporter pfam04973
Nicotinamide mononucleotide transporter; Members of this family are integral membrane proteins ...
55-242 1.05e-19

Nicotinamide mononucleotide transporter; Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.


Pssm-ID: 428230  Cd Length: 176  Bit Score: 83.36  E-value: 1.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614   55 SVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKELRATTKHEvqS 134
Cdd:pfam04973   1 SWLELIAALLGLLCVWLAARGNIWNWPVGIISVLLYAYLFFQAGLYGDMGLQLYYFVMSIYGWYLWLRGRDQPVRRL--T 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  135 KKLTTFQALIYFVGTILLYFmivIISKKLGGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIIIWYNQFMvn 214
Cdd:pfam04973  79 RKEWLLLLLATVVGTALLGY---LLSAFTDAAVPYLDAFTTVLSIVAQWLMARRYVENWLLWIVVDIVSVPLYFYKGL-- 153
                         170       180
                  ....*....|....*....|....*...
gi 281376614  215 gtsisLSMLMLQIVMFLNSIYGSIIWLK 242
Cdd:pfam04973 154 -----YLTALLYVIYLINAIYGYINWRK 176
 
Name Accession Description Interval E-value
PnuC COG3201
Nicotinamide riboside transporter PnuC [Coenzyme transport and metabolism];
48-245 5.55e-21

Nicotinamide riboside transporter PnuC [Coenzyme transport and metabolism];


Pssm-ID: 442434  Cd Length: 203  Bit Score: 87.23  E-value: 5.55e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  48 FLFTKDASVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKELRAt 127
Cdd:COG3201   10 TLGGTPMSWLELIAVLFGLLSVWLAARRNIWNWPFGIISTLLYAYLFFQAKLYGDALLQVYYFIMSIYGWYQWKRGRDN- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614 128 tKHEVQSKKLTTFQALIYFVGTILLYFMIVIISKKL-GGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIII 206
Cdd:COG3201   89 -EGEVPVRRLSLKEWLLLIAAGVLGTLLLGYLLKAFtDSAVPYLDAFTTVLSLVAQWLMARKYVENWLLWIVVDIVSVPL 167
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 281376614 207 WYnqfmvngTSISLSMLMLQIVMFLNSIYGSIIWLKKSK 245
Cdd:COG3201  168 YF-------YKGLYLTAILYAVFLVLAIYGYRNWRKSAK 199
NMN_trans_PnuC TIGR01528
nicotinamide mononucleotide transporter PnuC; The PnuC protein of E. coli is membrane protein ...
55-245 1.28e-20

nicotinamide mononucleotide transporter PnuC; The PnuC protein of E. coli is membrane protein responsible for nicotinamide mononucleotide transport, subject to regulation by interaction with the NadR (also called NadI) protein (see TIGR01526). This model defines a region corresponding to most of the length of PnuC, found primarily in pathogens. The extreme N- and C-terminal regions are poorly conserved and not included in the alignment and model. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]


Pssm-ID: 273672  Cd Length: 189  Bit Score: 85.93  E-value: 1.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614   55 SVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKEL-RATTKHEVQ 133
Cdd:TIGR01528   2 SIIELIAGLMGILCVVLASEGKVSNYIFGLISAVIYLYIAYQTGLYAEVLLQLFFVIANIYGLFAWKKNSqQEENGVTSG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  134 SKKLTTFQALIYFVGTILLYFMIVIISKKLGGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIIIWYNQFmv 213
Cdd:TIGR01528  82 LKKLKGKGWTIILSTSVVLTVVIALILKFIGDNFPWLDSITFVIGIVAQILMVRRYRENWILWLLSNVVSIILWFLAF-- 159
                         170       180       190
                  ....*....|....*....|....*....|..
gi 281376614  214 ngtSISLSMLMLQIVMFLNSIYGSIIWLKKSK 245
Cdd:TIGR01528 160 ---TGSLAMLLTYIIYLFNSLYGFYNWNKSKK 188
NMN_transporter pfam04973
Nicotinamide mononucleotide transporter; Members of this family are integral membrane proteins ...
55-242 1.05e-19

Nicotinamide mononucleotide transporter; Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.


Pssm-ID: 428230  Cd Length: 176  Bit Score: 83.36  E-value: 1.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614   55 SVLVLILSISSIINLVLVDRGRITNYFWGSITTTAWVIIAIHTRLIGDIASQTFYLIMQFLGIYIWGKELRATTKHEvqS 134
Cdd:pfam04973   1 SWLELIAALLGLLCVWLAARGNIWNWPVGIISVLLYAYLFFQAGLYGDMGLQLYYFVMSIYGWYLWLRGRDQPVRRL--T 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281376614  135 KKLTTFQALIYFVGTILLYFmivIISKKLGGVQIWLDAALFPLAIVGQILMTFGYRSQWVAWNIINIINIIIWYNQFMvn 214
Cdd:pfam04973  79 RKEWLLLLLATVVGTALLGY---LLSAFTDAAVPYLDAFTTVLSIVAQWLMARRYVENWLLWIVVDIVSVPLYFYKGL-- 153
                         170       180
                  ....*....|....*....|....*...
gi 281376614  215 gtsisLSMLMLQIVMFLNSIYGSIIWLK 242
Cdd:pfam04973 154 -----YLTALLYVIYLINAIYGYINWRK 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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