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Conserved domains on  [gi|261362942|gb|ACX71673|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Interochromis loocki]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 556.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 241 ALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 261362942 321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 556.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 241 ALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 261362942 321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 1.40e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.37  E-value: 1.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   23 SSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQLQPSN---STLLIILGLTSTLI 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYIIMTFSTFLVFKL-----NKSTNINTLATSWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 261362942  235 KAPALTALTPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-298 2.55e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 76.69  E-value: 2.55e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   7 AILLFGLgLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQaaaaatllfaSVTNAWL----- 80
Cdd:COG1007  106 ALLLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLG----------ALSSGFLlygis 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 -----TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALIL 143
Cdd:COG1007  175 llygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALL 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 144 QL--------QPSNSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYIIMT 211
Cdd:COG1007  255 RLlveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMN 334

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 212 FSTFLVF-----KLNKSTNINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSAL 286
Cdd:COG1007  335 LGAFAVIlllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSV 414

                        330
                 ....*....|..
gi 261362942 287 LSLYFYLRLSYA 298
Cdd:COG1007  415 ISAYYYLRVVKA 426
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 98-295 3.37e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 70.36  E-value: 3.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS--------NSTLLIILGLTSTLIGGWGGL 169
Cdd:TIGR01770 209 ILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYilfgfseaWQIFLAIIAFLSMLIGNFGAL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  170 NQTQLRKILAYSSIAHLGWMILVLQFSPSI----TLLTLLTYIIMTFSTFLVFKLNKSTN------INTLATSWTKAPAL 239
Cdd:TIGR01770 289 AQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLLRSYKdewieyISDFAGLFKTNPIL 368

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 261362942  240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRL 295
Cdd:TIGR01770 369 AILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 556.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 241 ALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 261362942 321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 1.54e-132

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 381.58  E-value: 1.54e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-NSTLLIILGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPAL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLpST 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*..
gi 261362942 320 QLTYPLATSTAMTICLLPLTPAISALL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.03e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 339.11  E-value: 1.03e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-NSTLLIILGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPAL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPST 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 261362942 320 QLTYpLATSTAMTICLLPLTPAISALL 346
Cdd:MTH00112 321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 1.02e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 333.74  E-value: 1.02e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-NSTLLIILGLT 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPAL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPST 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*.
gi 261362942 320 QLTYPLATSTAMTICLLPLTPAISAL 345
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 2.02e-101

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 302.66  E-value: 2.02e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-NSTLLIILGLT 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPAlNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPAL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPST 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*...
gi 261362942 320 qLTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00200 321 -SNLLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 2.40e-76

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 238.68  E-value: 2.40e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQL-QPSNSTLLIILGLT 159
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPAL 239
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPST 319
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|.
gi 261362942 320 QLTYPLATSTAMTICLLPLTP 340
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLL 341
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-307 4.99e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 165.00  E-value: 4.99e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   1 MNPYILAILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGqweiqqITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLIILglTS 160
Cdd:MTH00160  82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIII--LS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPALT 240
Cdd:MTH00160 154 AIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIK 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 261362942 241 ALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNN 307
Cdd:MTH00160 234 FLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-318 3.28e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 144.26  E-value: 3.28e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  10 LFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIqqi 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  90 thplpSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNS--TLLIILGLTSTLIGGWG 167
Cdd:MTH00144  87 -----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMtfSTFLVFKLNKSTNINTLATSWTKAPALTALTPLIL 247
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVS--SGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISL 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 261362942 248 LSLGG-LPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTLTISPNNLTGLTPWRLPS 318
Cdd:MTH00144 240 LLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSS 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 15-329 3.18e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 141.46  E-value: 3.18e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASvtnawlTGQWEIQQITHPLP 94
Cdd:MTH00011  17 LGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKNIT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  95 STMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLII-LGLTSTLIGGWGGLNQTQ 173
Cdd:MTH00011  91 ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMNQTQ 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 174 LRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPALTALTPLILLSLGGL 253
Cdd:MTH00011 171 LRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGL 250

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 261362942 254 PPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAVTlTISPNNLTGLTPWRLPSTQLTYPLATST 329
Cdd:MTH00011 251 PPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM-YLSPTFSSLKSAPYEPKTKILISMCTLS 325
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-297 2.60e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 136.34  E-value: 2.60e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   8 ILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLlfasvtnawLTGQWEIQ 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALL---------LMGGSLSF 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  88 Q--ITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFaLILQLQPSNSTLLIILGLTSTLIGG 165
Cdd:MTH00197  73 SnlYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL-LILAFNSSSFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFSTFLVFKLNKSTNINTLATSWTKAPALTALTPL 245
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 261362942 246 ILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSY 297
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-266 5.66e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 92.40  E-value: 5.66e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHP-RAVEATTKYFLTQAAA-------------AATLLFASVTNAWL 80
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSsglflfgcallcgTTGGLHLSYINLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPsNSTLLIILGLTS 160
Cdd:MTH00196  84 NSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL-NVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYIIMT---FSTFLVFKLNKSTNINTLATSw 233
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSicvFSIILALNVYKNLIIEFSGLS- 241

                        250       260       270
                 ....*....|....*....|....*....|...
gi 261362942 234 TKAPALTALTPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00196 242 RRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 1.40e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.37  E-value: 1.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   23 SSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQLQPSN---STLLIILGLTSTLI 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYIIMTFSTFLVFKL-----NKSTNINTLATSWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 261362942  235 KAPALTALTPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-266 1.73e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 86.22  E-value: 1.73e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   8 ILLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEI 86
Cdd:MTH00199 101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  87 QQITHPLPS----TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLIILGLtSTL 162
Cdd:MTH00199 181 QGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVL-SII 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 163 IGGWGGLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYIIMT---FSTFLVFKLNKSTNINTLATSwTK 235
Cdd:MTH00199 260 YGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSicsFSIILSLKLTKGLIVEVSGLS-RK 338

                        250       260       270
                 ....*....|....*....|....*....|.
gi 261362942 236 APALTALTPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00199 339 NPVIALTLALTFLSIAGIPPLAGFLSKWLIL 369
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-298 2.55e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 76.69  E-value: 2.55e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   7 AILLFGLgLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQaaaaatllfaSVTNAWL----- 80
Cdd:COG1007  106 ALLLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLG----------ALSSGFLlygis 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 -----TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALIL 143
Cdd:COG1007  175 llygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALL 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 144 QL--------QPSNSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYIIMT 211
Cdd:COG1007  255 RLlveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMN 334

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 212 FSTFLVF-----KLNKSTNINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSAL 286
Cdd:COG1007  335 LGAFAVIlllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSV 414

                        330
                 ....*....|..
gi 261362942 287 LSLYFYLRLSYA 298
Cdd:COG1007  415 ISAYYYLRVVKA 426
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
97-295 1.22e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 74.47  E-value: 1.22e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALIL--------QLQPSNSTLLIILGLTSTLIGGWGG 168
Cdd:PRK05777 209 FLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLrllvvafgGLSEDWQQVLAIIAIASMLVGNLAA 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 169 LNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYIIMTFSTFLVFKLNKS-----TNINTLATSWTKAPAL 239
Cdd:PRK05777 289 LSQTNIKRLLAYSSIAHAGYLLVGLaagtAEGYSAVLFYLLAYLFMTLGAFGVISLLRRkggeaESISDFAGLSKRSPLL 368

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 261362942 240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRL 295
Cdd:PRK05777 369 AAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 98-295 3.37e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 70.36  E-value: 3.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS--------NSTLLIILGLTSTLIGGWGGL 169
Cdd:TIGR01770 209 ILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYilfgfseaWQIFLAIIAFLSMLIGNFGAL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  170 NQTQLRKILAYSSIAHLGWMILVLQFSPSI----TLLTLLTYIIMTFSTFLVFKLNKSTN------INTLATSWTKAPAL 239
Cdd:TIGR01770 289 AQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLLRSYKdewieyISDFAGLFKTNPIL 368

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 261362942  240 TALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRL 295
Cdd:TIGR01770 369 AILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-237 4.62e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 63.72  E-value: 4.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   9 LLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAV---------EATTKYFLTQAAAAATLLFASVTNAW 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  80 LTGQ--------------WEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQL 145
Cdd:MTH00198 273 FTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL 352

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 146 QPSnSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIImtfsTFLVFKLNKSTN 225
Cdd:MTH00198 353 VIT-SKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV----TYLVSALASFTV 427

                        250
                 ....*....|..
gi 261362942 226 INTLATSWTKAP 237
Cdd:MTH00198 428 ICTLEEFGTRTP 439
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 7.77e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 56.88  E-value: 7.77e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 261362942  290 YFYLRLSYAVTLTISPNNLTGLTPWRLPSTQLTYPLATSTAMTICLLPLTP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 9-273 3.18e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 60.93  E-value: 3.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942   9 LLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIQQ 88
Cdd:COG0651  112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMAD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  89 ITHPLPS----------TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGL--ILSTWQKLAPFALILQL 145
Cdd:COG0651  192 LAARLAEldpglllaafALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFL 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 146 QPsnstLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMT--------FSTFLV 217
Cdd:COG0651  272 GT----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHalakallfLAAGAI 347

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 261362942 218 FKLNKSTNINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKWLILQELAKQG 273
Cdd:COG0651  348 ERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAG 403
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 100-191 3.70e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 54.56  E-value: 3.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  100 LALALKIGLAPLHAWLPEV-LQGLDLTTGLILSTWQKLAPFALI---LQLQPSNS----TLLIILGLTSTLIGGWGGLNQ 171
Cdd:TIGR01972 211 IAFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLrfnLPLFPDASlyfaPVLAALGVIAIIYGALIALAQ 290

                          90       100
                  ....*....|....*....|
gi 261362942  172 TQLRKILAYSSIAHLGWMIL 191
Cdd:TIGR01972 291 TDIKRLIAYSSISHMGFVLL 310
ndhB CHL00049
NADH dehydrogenase subunit 2
 98-295 5.73e-08

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 54.24  E-value: 5.73e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQ----PSNST----LLIILGLTSTLIGGWGGL 169
Cdd:CHL00049 220 ITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSNewhlLLEILAILSMILGNLIAI 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 170 NQTQLRKILAYSSIAHLGW-MILVLQFSPSI---TLLT-LLTYIIM---TFSTFLVFKLNKST-NINTLATSWTKAPALT 240
Cdd:CHL00049 300 TQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDgyaSMITyMLFYIFMnlgTFACIVLFGLRTGTdNIRDYAGLYTKDPFLA 379

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 261362942 241 ALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRL 295
Cdd:CHL00049 380 LSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 78-193 3.52e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 48.61  E-value: 3.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  78 AWLTGQWEIQQI----THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQG-----------LDLTTGLILstwqk 135
Cdd:COG1009  186 GAIAGTLNFSELlaaaPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDAMEGptpvsallhaaTMVKAGVYL----- 260

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 261362942 136 LAPFALILQLQPSNSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:COG1009  261 LARLSPLFALSPVWLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-299 4.47e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 48.34  E-value: 4.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI----------LQLQPSNSTLLIILGLTSTLIGG 165
Cdd:PRK08375 207 FVLLALALKAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGS 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFS----PSITLLTLLTYIIMTFSTFL----VFKLNKSTNINTLATSWTKAP 237
Cdd:PRK08375 287 LAALGQDDVKRVLAYSTVSQMGYILLGLALLtplaLAAGLLHLLHHALMKGALFLaagaIEVTYGTRRLSELSGLGRRMP 366

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 261362942 238 ALTALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYAV 299
Cdd:PRK08375 367 LTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRA 428
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 100-191 4.78e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 48.15  E-value: 4.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 100 LALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFALI---LQLQP----SNSTLLIILGLTSTLIGGWG 167
Cdd:COG1008  217 IAFAVKVPMFPFHTWLPDAHVeaptaGSVLLAGVLL----KMGGYGLLrfaLPLFPeasaYFAPLLAALGVIGIIYGALV 292

                         90       100
                 ....*....|....*....|....
gi 261362942 168 GLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:COG1008  293 ALAQTDLKRLIAYSSVSHMGFVLL 316
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 92-299 9.10e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 47.27  E-value: 9.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  92 PLPSTMITLALAL-----KIGLAPLHAWLPEV-----------LQGLDLTTG---------LILSTWQKLAPFALILqlq 146
Cdd:PRK12667 218 PPLALGVALALALwaftiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAAL--- 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 147 psnSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYII-------MTFSTFLVF- 218
Cdd:PRK12667 295 ---SPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksLLFLASGVFi 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 219 KLNKSTNINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKWLILQELAKQGLAPTATLAALSALLSLYFYLRLSYA 298
Cdd:PRK12667 372 HAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451


                 .
gi 261362942 299 V 299
Cdd:PRK12667 452 L 452
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-193 3.71e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 45.69  E-value: 3.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  81 TGQWEIQQI-THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTL 152
Cdd:PRK12644 184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLAPGFADV 263

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 261362942 153 ------LIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK12644 264 pvwrptVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 85-193 3.88e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 45.31  E-value: 3.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  85 EIQQITHPLPSTMITLALAL-------KIGLAPLHAWLPE-----------VLQGLDLTTGLILSTWQKLAPFALILQLQ 146
Cdd:PRK06458 200 ELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYILIDAAIGSDF 279

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 261362942 147 PSNstLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK06458 280 PGR--LLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFAL 324
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
96-202 4.83e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 45.09  E-value: 4.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQLQPSNSTL----LIILGLTSTLIGGWG 167
Cdd:PRK07363 209 TGLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGgVLAKLGTYGLLrfgLQLFPQTWSLvapgLAIIGTISVIYGALS 288

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 261362942 168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLL 202
Cdd:PRK07363 289 AIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 75-191 5.59e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 44.81  E-value: 5.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  75 VTNAWLTGQWEIQQI-THPLPSTMITL-------ALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFAL 141
Cdd:PRK05846 186 VVYYNATGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPDAHVqaptaGSVLLAGILL----KMGAYGL 261

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 261362942 142 I---LQLQPSNS----TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK05846 262 LrfsLPLFPDAShefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTL 318
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-227 6.94e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 43.71  E-value: 6.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNSTLLIILGLTSTLIGGWgglNQTQLRK 176
Cdd:MTH00091  62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMF---LLKSYKN 138

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 261362942 177 ILAYSSIAHLGWMILVLQFSPSITLLTLLTYIIMTFstFLVFKLNKSTNIN 227
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLML--FLIPKFNNVNKLN 187
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
102-262 8.25e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 44.27  E-value: 8.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 102 LALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQ----PSNST----LLIILGLTSTLIGGWGGLNQTQ 173
Cdd:PRK02504 220 IAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLvtafPSFDEqwklLFTALAILSMVLGNVVALAQTS 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 174 LRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYIIMT---FSTFLVFKLNKSTN-INTLATSWTKAPALTALTPL 245
Cdd:PRK02504 300 MKRMLAYSSIGQAGFVMIGLvagtEAGYASMVFYLLAYLFMNlgaFACVILFSLRTGTDqISDYAGLYQKDPLLTLGLSL 379

                        170
                 ....*....|....*..
gi 261362942 246 ILLSLGGLPPLTGFMPK 262
Cdd:PRK02504 380 CLLSLGGIPPLAGFFGK 396
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-207 2.98e-04

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 42.76  E-value: 2.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 111 LHAWLPEVLQGLDLTTGLI-LSTWQKLAPFALI-----LQLQPSNSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrssplFEQAPLALIIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                         90       100
                 ....*....|....*....|....
gi 261362942 185 HLGWMILVLQFSP-SITLLTLLTY 207
Cdd:MTH00020 309 QLGYMVVACGLSHySISLFHLMNH 332
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 98-266 3.61e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 42.41  E-value: 3.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI-----------LQLQPSNSTLLIILGLTSTLIGG 165
Cdd:PRK12662 215 IMVGLFIKAALFPFHKWLIQAYSEAPSFISVFFSgTSTKVMIYLIIrivydvfkanfVFTTLPFNNVFMILAALAIVFGS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYII----MTFSTFLV-----FKLNkSTNINTLATSWTKA 236
Cdd:PRK12662 295 VLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVnhsiVKSALFMVsgsisYHFG-TTKLEDCLNLWKSM 373

                        170       180       190
                 ....*....|....*....|....*....|
gi 261362942 237 PALTALTPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:PRK12662 374 PKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 100-191 7.10e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.17  E-value: 7.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 100 LALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQLQPSN----STLLIILGLTSTLIGGWGGLNQ 171
Cdd:PRK12561 193 IAFGVKLPIFPLHTWLPDAHGEASAPVSMILAgVLLKMGGYALIrfnVQMLPDAhvyfAPALAILGVVNIIYGALNAFAQ 272

                         90       100
                 ....*....|....*....|
gi 261362942 172 TQLRKILAYSSIAHLGWMIL 191
Cdd:PRK12561 273 DNVKRRLAYSSVSHMGFVLL 292
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-191 7.44e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 41.55  E-value: 7.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 110 PLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSNS------TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK07376 245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPVFEqfpavmTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324


                 ....*...
gi 261362942 184 AHLGWMIL 191
Cdd:PRK07376 325 SQLGYMVM 332
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 96-209 8.52e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 40.89  E-value: 8.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  96 TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGLilstWQKLAPFALILQLQ--PSNSTLLIILGLTSTL 162
Cdd:PRK08676 210 LFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQSGaaEQFSNVLIGLGIFSIA 285

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 261362942 163 IGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYII 209
Cdd:PRK08676 286 VAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
PRK12650 PRK12650
DUF4040 family protein;
110-190 1.20e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 40.80  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 110 PLHAWLPEVLQGLD-----------LTTGLILstwqkLAPFALILQLQPSNSTLLIILGLTSTLIGGWGGLNQTQLRKIL 178
Cdd:PRK12650 226 PFHFWLPEAMAAITpvsaflhaaavVKAGIYL-----LLRFSPVFHDVAVWNWLLIIVGMITALMGAVFAVQKTDLKKLT 300

                         90
                 ....*....|..
gi 261362942 179 AYSSIAHLGWMI 190
Cdd:PRK12650 301 AYSTVSQLGWIV 312
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 1.24e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 40.71  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 111 LHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQP----SNSTLLII--LGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekAPLTLLIItiFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 261362942 185 HLGWMILVL 193
Cdd:MTH00032 324 QLGYMVLII 332
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
98-191 1.69e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.07  E-value: 1.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  98 ITLALALKIGLAPLHAWLPE-----------VLQG--LDLTT--------GLILSTWQKLAPFalilqlqpsnstlLIIL 156
Cdd:PRK06473 211 ILVGFGIKIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPW-------------LATW 277

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 261362942 157 GLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK06473 278 AVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILL 312
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 96-193 2.53e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 39.75  E-value: 2.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTW-QKLAPFAL---ILQLQPSNS-----TLLIILGLTSTLIGGW 166
Cdd:PRK08377 210 ALLIFGLAVEAELFPLNAWAPDAYQAAPHPITVMFSAFvVKAGLYAMariLYLMQNANGwssvlKLVIIMATLTVFFAEL 289

                         90       100
                 ....*....|....*....|....*..
gi 261362942 167 GGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK08377 290 SALRQKNVKRMIAYSSIGQVGMIALAL 316
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-200 3.37e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 39.26  E-value: 3.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942 100 LALALKIGLAPLHAWLPE-----------VLQGLDLTTG---LILSTWQKL-------APFALILQLqpsnstLLIILGL 158
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQahveapvagsvILAGVLLKLGgygFIRFSWPLLpeaseyfSPLIQTLSL------LAIIYGS 287

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 261362942 159 TSTLiggwgglNQTQLRKILAYSSIAHLGWMILVLqFSPSIT 200
Cdd:MTH00217 288 LTTC-------RQVDLKRIIAYSSVAHMGLVTLGI-FSHTIQ 321
ND5 MTH00066
NADH dehydrogenase subunit 5; Provisional
 78-189 9.18e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214416 [Multi-domain]  Cd Length: 598  Bit Score: 37.97  E-value: 9.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 261362942  78 AWL---TGQWEIQQITHPLPSTMITL-----ALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQP-- 147
Cdd:MTH00066 185 AWLamnTNSWELQQIFLLNDNSTLPLlglilAAAGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRFHPll 264

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 261362942 148 -SNSTLLII---LGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWM 189
Cdd:MTH00066 265 eNNQTALTIclcLGALTTLFTAACALTQNDIKKIVAFSTSSQLGLM 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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