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Conserved domains on  [gi|91806698|gb|ABE66076|]
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myb family transcription factor [Arabidopsis thaliana]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 999994)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03091 super family cl33633
hypothetical protein; Provisional
 212-321 1.01e-29

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03091:

Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 120.08  E-value: 1.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698  212 KSTLVKGQWTAEEDRVLIQLVEKYGLRKWSHIAQvLPG--RIGKQCRERWHNHLRPDIKKETWSEEEDRVLIEFHKEIGN 289
Cdd:PLN03091   9 KQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPK-QAGlqRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGN 87

                         90       100       110
                 ....*....|....*....|....*....|..
gi 91806698  290 KWAEIAKRLPGRTENSIKNHWNATKRRQFSKR 321
Cdd:PLN03091  88 RWSQIAAQLPGRTDNEIKNLWNSCLKKKLRQR 119
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 212-321 1.01e-29

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 120.08  E-value: 1.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698  212 KSTLVKGQWTAEEDRVLIQLVEKYGLRKWSHIAQvLPG--RIGKQCRERWHNHLRPDIKKETWSEEEDRVLIEFHKEIGN 289
Cdd:PLN03091   9 KQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPK-QAGlqRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGN 87

                         90       100       110
                 ....*....|....*....|....*....|..
gi 91806698  290 KWAEIAKRLPGRTENSIKNHWNATKRRQFSKR 321
Cdd:PLN03091  88 RWSQIAAQLPGRTDNEIKNLWNSCLKKKLRQR 119
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 211-316 2.38e-23

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 102.17  E-value: 2.38e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698 211 KKSTLVKGQWTAEEDRVLIQLVEKYGLRKWSHIAQVLPGRIGKQCRERWHNHLRPDIKKETWSEEEDRVLIEFHKEIGNK 290
Cdd:COG5147  14 MQTKRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ 93

                        90       100
                ....*....|....*....|....*.
gi 91806698 291 WAEIAKRLPGRTENSIKNHWNATKRR 316
Cdd:COG5147  94 WSTIADYKDRRTAQQCVERYVNTLED 119
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 220-280 1.13e-18

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 79.28  E-value: 1.13e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 91806698   220 WTAEEDRVLIQLVEKYGlRKWSHIAQVLPGRIGKQCRERWHNHLRPDIKKETWSEEEDRVL 280
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 220-263 4.38e-15

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 68.76  E-value: 4.38e-15
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 91806698 220 WTAEEDRVLIQLVEKYGLRKWSHIAQVLPGRIGKQCRERWHNHL 263
Cdd:cd00167   2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
217-265 5.69e-15

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 68.79  E-value: 5.69e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 91806698    217 KGQWTAEEDRVLIQLVEKYGLRKWSHIAQVLPGRIGKQCRERWHNHLRP 265
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 212-321 1.01e-29

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 120.08  E-value: 1.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698  212 KSTLVKGQWTAEEDRVLIQLVEKYGLRKWSHIAQvLPG--RIGKQCRERWHNHLRPDIKKETWSEEEDRVLIEFHKEIGN 289
Cdd:PLN03091   9 KQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPK-QAGlqRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGN 87

                         90       100       110
                 ....*....|....*....|....*....|..
gi 91806698  290 KWAEIAKRLPGRTENSIKNHWNATKRRQFSKR 321
Cdd:PLN03091  88 RWSQIAAQLPGRTDNEIKNLWNSCLKKKLRQR 119
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 212-330 2.24e-25

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 104.00  E-value: 2.24e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698  212 KSTLVKGQWTAEEDRVLIQLVEKYGLRKWSHI---AQVLpgRIGKQCRERWHNHLRPDIKKETWSEEEDRVLIEFHKEIG 288
Cdd:PLN03212  20 KMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLpkrAGLL--RCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLG 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 91806698  289 NKWAEIAKRLPGRTENSIKNHWNATKRRQFSKRKCRSKYPRP 330
Cdd:PLN03212  98 NRWSLIAGRIPGRTDNEIKNYWNTHLRKKLLRQGIDPQTHKP 139
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 211-316 2.38e-23

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 102.17  E-value: 2.38e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698 211 KKSTLVKGQWTAEEDRVLIQLVEKYGLRKWSHIAQVLPGRIGKQCRERWHNHLRPDIKKETWSEEEDRVLIEFHKEIGNK 290
Cdd:COG5147  14 MQTKRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ 93

                        90       100
                ....*....|....*....|....*.
gi 91806698 291 WAEIAKRLPGRTENSIKNHWNATKRR 316
Cdd:COG5147  94 WSTIADYKDRRTAQQCVERYVNTLED 119
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 220-280 1.13e-18

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 79.28  E-value: 1.13e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 91806698   220 WTAEEDRVLIQLVEKYGlRKWSHIAQVLPGRIGKQCRERWHNHLRPDIKKETWSEEEDRVL 280
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 217-263 1.36e-15

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 70.23  E-value: 1.36e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 91806698   217 KGQWTAEEDRVLIQLVEKYGlRKWSHIAQVLPGRIGKQCRERWHNHL 263
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 220-263 4.38e-15

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 68.76  E-value: 4.38e-15
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 91806698 220 WTAEEDRVLIQLVEKYGLRKWSHIAQVLPGRIGKQCRERWHNHL 263
Cdd:cd00167   2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
217-265 5.69e-15

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 68.79  E-value: 5.69e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 91806698    217 KGQWTAEEDRVLIQLVEKYGLRKWSHIAQVLPGRIGKQCRERWHNHLRP 265
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 269-311 1.97e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 67.14  E-value: 1.97e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 91806698   269 KETWSEEEDRVLIEFHKEIGNKWAEIAKRLPGRTENSIKNHWN 311
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
269-316 4.24e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 60.70  E-value: 4.24e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 91806698    269 KETWSEEEDRVLIEFHKEIG-NKWAEIAKRLPGRTENSIKNHWNATKRR 316
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 271-314 8.68e-12

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 59.51  E-value: 8.68e-12
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 91806698 271 TWSEEEDRVLIEFHKEIG-NKWAEIAKRLPGRTENSIKNHWNATK 314
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 272-320 3.74e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 49.62  E-value: 3.74e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 91806698   272 WSEEEDRVLIEFHKEIGNKWAEIAKRLPGRTENSIKNHWNATKRRQFSK 320
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLNPKISR 49
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 207-326 1.68e-07

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 53.25  E-value: 1.68e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91806698 207 WKETKKSTLVKGQWTAEEDRVLIQLVEKYGLRkWSHIAQVLPGRIGKQCRERWHNHLRPDIKKEtWSEEEDRVLIEFHKE 286
Cdd:COG5147  62 WNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ-WSTIADYKDRRTAQQCVERYVNTLEDLSSTH-DSKLQRRNEFDKIDP 139

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 91806698 287 IGNKWAEIAKRLPGRTENSIKNHWnatkrRQFSKRKCRSK 326
Cdd:COG5147 140 FNENSARRPDIYEDELLEREVNRE-----ASYRLRVPRVS 174
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
 265-302 7.12e-05

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 40.37  E-value: 7.12e-05
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 91806698 265 PDIKKETWSEEEDRVLIEFHKEIGNKWAEIAKrLPGRT 302
Cdd:cd11659   1 PSIKKTEWTREEDEKLLHLAKLLPTQWRTIAP-IVGRT 37
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 220-261 8.98e-05

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 39.86  E-value: 8.98e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 91806698 220 WTAEEDRVLIQLVEKYGLRKWSHIAQ---VLPGRIGKQCRERWHN 261
Cdd:cd11660   3 WTDEEDEALVEGVEKYGVGNWAKILKdyfFVNNRTSVDLKDKWRN 47
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
 214-259 2.51e-03

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 35.75  E-value: 2.51e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 91806698 214 TLVKGQWTAEEDRVLIQLVEKYGLRkWSHIAQVLpGRIGKQCRERW 259
Cdd:cd11659   2 SIKKTEWTREEDEKLLHLAKLLPTQ-WRTIAPIV-GRTAQQCLERY 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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