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Conserved domains on  [gi|63020636|gb|AAY26234|]
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expressed in synovial lining protein [Homo sapiens]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 13885110)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain; similar to Homo sapiens interleukin-27 subunit beta that associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III domain-containing protein similar to mammalian interleukin-9 and interleukin-21 receptors, and vertebrate phytanoyl-CoA hydroxylase-interacting protein; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh), also called ABI gene family member 3-binding protein (ABI3BP), with 2 repeats; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III domain-containing protein similar to mammalian interleukin-9 and interleukin-21 receptors, and vertebrate phytanoyl-CoA hydroxylase-interacting protein; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh), also called ABI gene family member 3-binding protein (ABI3BP), with 2 repeats

Gene Ontology:  GO:0005515

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1600-1691 3.83e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 3.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636 1600 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1675
Cdd:cd00063    3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                         90
                 ....*....|....*.
gi 63020636 1676 NPHGYGPISPSVSFVT 1691
Cdd:cd00063   78 NGGGESPPSESVTVTT 93
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 580-1012 6.79e-12

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 70.97  E-value: 6.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   580 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 655
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   656 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 735
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   736 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 815
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   816 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 895
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   896 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 974
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 63020636   975 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 1012
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 310-400 6.94e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 6.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  310 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 389
Cdd:cd00063    3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                         90
                 ....*....|.
gi 63020636  390 GLGPHSKAFIV 400
Cdd:cd00063   81 GESPPSESVTV 91
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 759-1300 1.14e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   759 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 833
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   834 PATVVndhvPSSSRQPisrgwedlrrSPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 913
Cdd:PHA03247 2551 PPPPL----PPAAPPA----------APDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   914 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 993
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   994 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1069
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1070 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1149
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1150 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1226
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63020636  1227 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1300
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 209-302 2.41e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.97  E-value: 2.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  209 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 286
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                         90
                 ....*....|....*.
gi 63020636  287 QGERDGKWSTSVFQRT 302
Cdd:cd00063   78 NGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 3-68 3.60e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.84  E-value: 3.60e-06
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63020636       3 LKVTWDPPKDATSR-PVEHYNIAYGKSLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVS 68
Cdd:smart00060   17 VTLSWEPPPDDGITgYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 106-192 4.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  106 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 182
Cdd:cd00063    1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76

                         90
                 ....*....|
gi 63020636  183 MNSQGRSQPV 192
Cdd:cd00063   77 VNGGGESPPS 86
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1600-1691 3.83e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 3.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636 1600 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1675
Cdd:cd00063    3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                         90
                 ....*....|....*.
gi 63020636 1676 NPHGYGPISPSVSFVT 1691
Cdd:cd00063   78 NGGGESPPSESVTVTT 93
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 580-1012 6.79e-12

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 70.97  E-value: 6.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   580 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 655
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   656 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 735
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   736 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 815
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   816 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 895
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   896 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 974
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 63020636   975 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 1012
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 310-400 6.94e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 6.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  310 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 389
Cdd:cd00063    3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                         90
                 ....*....|.
gi 63020636  390 GLGPHSKAFIV 400
Cdd:cd00063   81 GESPPSESVTV 91
fn3 pfam00041
Fibronectin type III domain;
310-395 8.43e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 8.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636    310 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 389
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 63020636    390 GLGPHS 395
Cdd:pfam00041   80 GEGPPS 85
PHA03247 PHA03247
large tegument protein UL36; Provisional
 759-1300 1.14e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   759 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 833
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   834 PATVVndhvPSSSRQPisrgwedlrrSPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 913
Cdd:PHA03247 2551 PPPPL----PPAAPPA----------APDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   914 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 993
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   994 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1069
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1070 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1149
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1150 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1226
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63020636  1227 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1300
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 209-302 2.41e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.97  E-value: 2.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  209 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 286
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                         90
                 ....*....|....*.
gi 63020636  287 QGERDGKWSTSVFQRT 302
Cdd:cd00063   78 NGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1600-1681 5.48e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 51.85  E-value: 5.48e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636    1600 APRNITVVAVEGchSFVIVDWDKAtPGDVVTGYLV-YSASYEDfIRNKWSTQASSV--THLPIENLKPNTRYYFKVQAQN 1676
Cdd:smart00060    3 PPSNLRVTDVTS--TSVTLSWEPP-PDDGITGYIVgYRVEYRE-EGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 63020636    1677 PHGYG 1681
Cdd:smart00060   79 GAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1600-1684 4.37e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 49.34  E-value: 4.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   1600 APRNITVVAVEgcHSFVIVDWDKATPGD-VVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPH 1678
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNgPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 63020636   1679 GYGPIS 1684
Cdd:pfam00041   80 GEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
209-295 1.02e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.18  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636    209 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGELARWDYKQIAN--RRVLIENLIPDTVYEFAVRIS 286
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSW-TPPPDGNGPIT---GYEVEYRPKNSGEPWNEITVPGttTSVTLTGLKPGTEYEVRVQAV 76


                   ....*....
gi 63020636    287 QGERDGKWS 295
Cdd:pfam00041   77 NGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 310-392 1.30e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.99  E-value: 1.30e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636     310 APENLNVWPVNgkPTVVAASWDALPETEGKvkEYILSYAPALKPFGA--KSLTYPGDTTSALVDGLQPGERYLFKIRATN 387
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGIT--GYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 63020636     388 RRGLG 392
Cdd:smart00060   79 GAGEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
211-452 2.77e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.31  E-value: 2.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  211 PDDISVRVMSSQSVLVSWvDPVLEKqkkvvASRQYTVrYREKGELARWdyKQIANRRVLI---ENLIPDTVYEFAVR-IS 286
Cdd:COG3401  236 PTGLTATADTPGSVTLSW-DPVTES-----DATGYRV-YRSNSGDGPF--TKVATVTTTSytdTGLTNGTTYYYRVTaVD 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  287 QGERDGKWSTSVfQRTPESAPTTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPAlKPFGAKSLTYPGDTT 366
Cdd:COG3401  307 AAGNESAPSNVV-SVTTDLTPPAAPSGLTA--TAVGSSSITLSWT--ASSDADVTGYNVYRSTS-GGGTYTKIAETVTTT 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  367 SALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTskaDVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASPQ 446
Cdd:COG3401  381 SYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTAS---AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAV 457


                 ....*.
gi 63020636  447 GRNAKD 452
Cdd:COG3401  458 LADGGD 463
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 3-68 3.60e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.84  E-value: 3.60e-06
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63020636       3 LKVTWDPPKDATSR-PVEHYNIAYGKSLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVS 68
Cdd:smart00060   17 VTLSWEPPPDDGITgYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 211-284 1.39e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 44.91  E-value: 1.39e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63020636     211 PDDISVRVMSSQSVLVSWVDPVLEKQKKvvasrqYTVRYREKGELARWDYKQI----ANRRVLIENLIPDTVYEFAVR 284
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDGITG------YIVGYRVEYREEGSEWKEVnvtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 3-75 1.96e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.96e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 63020636    3 LKVTWDPPKDATSrPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVSRPVYRAE 75
Cdd:cd00063   17 VTLSWTPPEDDGG-PITGYVVEYREkgSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVT 90
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
271-390 2.04e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 49.62  E-value: 2.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  271 ENLIPDTVYEFAVRISQGERDGKWSTSVFQRTPESAPtTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPA 350
Cdd:COG3401  197 GDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTA--TADTPGSVTLSWD--PVTESDATGYRVYRSNS 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 63020636  351 lkpfGAKSLTYPGDT--TSALVDGLQPGERYLFKIRATNRRG 390
Cdd:COG3401  272 ----GDGPFTKVATVttTSYTDTGLTNGTTYYYRVTAVDAAG 309
fn3 pfam00041
Fibronectin type III domain;
3-70 4.49e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.86  E-value: 4.49e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636      3 LKVTWDPPKDAtSRPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVSRP 70
Cdd:pfam00041   16 LTVSWTPPPDG-NGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 106-192 4.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  106 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 182
Cdd:cd00063    1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76

                         90
                 ....*....|
gi 63020636  183 MNSQGRSQPV 192
Cdd:cd00063   77 VNGGGESPPS 86
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1600-1691 3.83e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 3.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636 1600 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1675
Cdd:cd00063    3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                         90
                 ....*....|....*.
gi 63020636 1676 NPHGYGPISPSVSFVT 1691
Cdd:cd00063   78 NGGGESPPSESVTVTT 93
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 580-1012 6.79e-12

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 70.97  E-value: 6.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   580 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 655
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   656 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 735
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   736 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 815
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   816 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 895
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   896 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 974
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 63020636   975 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 1012
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 310-400 6.94e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 6.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  310 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 389
Cdd:cd00063    3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                         90
                 ....*....|.
gi 63020636  390 GLGPHSKAFIV 400
Cdd:cd00063   81 GESPPSESVTV 91
fn3 pfam00041
Fibronectin type III domain;
310-395 8.43e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 8.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636    310 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 389
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 63020636    390 GLGPHS 395
Cdd:pfam00041   80 GEGPPS 85
PHA03247 PHA03247
large tegument protein UL36; Provisional
 759-1300 1.14e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   759 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 833
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   834 PATVVndhvPSSSRQPisrgwedlrrSPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 913
Cdd:PHA03247 2551 PPPPL----PPAAPPA----------APDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   914 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 993
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   994 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1069
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1070 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1149
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1150 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1226
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63020636  1227 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1300
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 872-1301 2.04e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.88  E-value: 2.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   872 PIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRMTPgrAPQ 951
Cdd:PHA03307   78 EAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP--PAA 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   952 QQPPPPVATSQHHPG---------PQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSrgmlPTALQNQDED 1022
Cdd:PHA03307  156 GASPAAVASDAASSRqaalplsspEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA----PAPGRSAADD 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1023 AQGSYDDDSTEVEAQDVRAPAHAARakeaaasLPKHQQVESPT--GAGAGGDHRSQRghaASPARPSrpGGPQSRARVPS 1100
Cdd:PHA03307  232 AGASSSDSSSSESSGCGWGPENECP-------LPRPAPITLPTriWEASGWNGPSSR---PGPASSS--SSPRERSPSPS 299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1101 RAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGFfkggkedlLSSSVPKWPSSSTPRGGKDADGSlakeerepaialAP 1180
Cdd:PHA03307  300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSE--------SSRGAAVSPGPSPSRSPSPSRPP------------PP 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1181 RGGSlaPVKRPLPPPPGSSPRASHVPSRLPPRSAATVSPvagthpwpqyttrappghfsttpmlslRQRMMHARFRNPLS 1260
Cdd:PHA03307  360 ADPS--SPRKRPRPSRAPSSPAASAGRPTRRRARAAVAG---------------------------RARRRDATGRFPAG 410

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 63020636  1261 RQPARPSYRQGYNGRPNVE-------GKVLPGSNGKPNGqRIINGPQG 1301
Cdd:PHA03307  411 RPRPSPLDAGAASGAFYARyplltpsGEPWPGSPPPPPG-RVRYGGLG 457
PHA03247 PHA03247
large tegument protein UL36; Provisional
 425-1078 2.40e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 2.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   425 PSSPSPRAPASSQHPSVPAS---PQGRNAKDLLLDLKNKILANGGAPRKPQLRAKKAEELdlqsTEITGEEELGSRED-- 499
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAGAapdPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRML----TWIRGLEELASDDAgd 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   500 -----SPMSPSDTQDQKrtlRPPSRHGHSVVAPGRTAvRARMPALPRRegvdkpgfslATQPR-PGAPPSASASPAHHAS 573
Cdd:PHA03247 2551 pppplPPAAPPAAPDRS---VPPPRPAPRPSEPAVTS-RARRPDAPPQ----------SARPRaPVDDRGDPRGPAPPSP 2616

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   574 TQGTSHRPSLPASLNdndlvDSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRS-SVHPGAKPASPARRTPHSG 652
Cdd:PHA03247 2617 LPPDTHAPDPPPPSP-----SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRRRAARPT 2691

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   653 AAEEDSSASAPPsrlsPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSvsshlssrTQVSEGAEAS 732
Cdd:PHA03247 2692 VGSLTSLADPPP----PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA--------TPGGPARPAR 2759

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   733 DGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTV--PSRAHPRVP 810
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLppPTSAQPTAP 2839

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   811 SHSDSHPKLSSGIHGDEEDEKPL----PATVVNDHVPSSSRQPISR-GWEDLRRSPQrgaSLHRKEPIPENPKSTGADTH 885
Cdd:PHA03247 2840 PPPPGPPPPSLPLGGSVAPGGDVrrrpPSRSPAAKPAAPARPPVRRlARPAVSRSTE---SFALPPDQPERPPQPQAPPP 2916

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   886 PQgkysslaskaqdVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPR----RMTPGRAPQQQPPPpvats 961
Cdd:PHA03247 2917 PQ------------PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQpwlgALVPGRVAVPRFRV----- 2979

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   962 qhhpgPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRS---HSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQD 1038
Cdd:PHA03247 2980 -----PQPAPSREAPASSTPPLTGHSLSRVSSWASSlalHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEA 3054

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 63020636  1039 VRApahaarAKEAAASLPKHQQVESPTGAGAGGDHRSQRG 1078
Cdd:PHA03247 3055 LDP------LPPEPHDPFAHEPDPATPEAGARESPSSQFG 3088
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 209-302 2.41e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.97  E-value: 2.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  209 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 286
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                         90
                 ....*....|....*.
gi 63020636  287 QGERDGKWSTSVFQRT 302
Cdd:cd00063   78 NGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1600-1681 5.48e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 51.85  E-value: 5.48e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636    1600 APRNITVVAVEGchSFVIVDWDKAtPGDVVTGYLV-YSASYEDfIRNKWSTQASSV--THLPIENLKPNTRYYFKVQAQN 1676
Cdd:smart00060    3 PPSNLRVTDVTS--TSVTLSWEPP-PDDGITGYIVgYRVEYRE-EGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 63020636    1677 PHGYG 1681
Cdd:smart00060   79 GAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1600-1684 4.37e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 49.34  E-value: 4.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   1600 APRNITVVAVEgcHSFVIVDWDKATPGD-VVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPH 1678
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNgPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 63020636   1679 GYGPIS 1684
Cdd:pfam00041   80 GEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
209-295 1.02e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.18  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636    209 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGELARWDYKQIAN--RRVLIENLIPDTVYEFAVRIS 286
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSW-TPPPDGNGPIT---GYEVEYRPKNSGEPWNEITVPGttTSVTLTGLKPGTEYEVRVQAV 76


                   ....*....
gi 63020636    287 QGERDGKWS 295
Cdd:pfam00041   77 NGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 310-392 1.30e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.99  E-value: 1.30e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636     310 APENLNVWPVNgkPTVVAASWDALPETEGKvkEYILSYAPALKPFGA--KSLTYPGDTTSALVDGLQPGERYLFKIRATN 387
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGIT--GYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 63020636     388 RRGLG 392
Cdd:smart00060   79 GAGEG 83
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 418-797 1.49e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 53.64  E-value: 1.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   418 GKPEKPEPSSPSPRAPassqhPSVPASPQGRNAKDLLLDLKnkilANGGAPRKPQLRAKKAEELDLQSTEITGEeelgSR 497
Cdd:PHA03307  104 GSPTPPGPSSPDPPPP-----TPPPASPPPSPAPDLSEMLR----PVGSPGPPPAASPPAAGASPAAVASDAAS----SR 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   498 EDSPMSPSdTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSASASPAHHASTQGT 577
Cdd:PHA03307  171 QAALPLSS-PEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGW 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   578 SHRPSLPASLNDNDLVDSDEDERAVGSLHPkgafaqPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEED 657
Cdd:PHA03307  250 GPENECPLPRPAPITLPTRIWEASGWNGPS------SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE 323

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   658 SSASAPPSRLSPPHGGSSRllPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGesh 737
Cdd:PHA03307  324 SSSSSTSSSSESSRGAAVS--PGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRA--- 398

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   738 gdgdredggRQAEATAQTLRARPASGhfhllrhkPFAANGRSPSRFSigRGPRLQPSSSP 797
Cdd:PHA03307  399 ---------RRRDATGRFPAGRPRPS--------PLDAGAASGAFYA--RYPLLTPSGEP 439
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
211-452 2.77e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.31  E-value: 2.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  211 PDDISVRVMSSQSVLVSWvDPVLEKqkkvvASRQYTVrYREKGELARWdyKQIANRRVLI---ENLIPDTVYEFAVR-IS 286
Cdd:COG3401  236 PTGLTATADTPGSVTLSW-DPVTES-----DATGYRV-YRSNSGDGPF--TKVATVTTTSytdTGLTNGTTYYYRVTaVD 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  287 QGERDGKWSTSVfQRTPESAPTTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPAlKPFGAKSLTYPGDTT 366
Cdd:COG3401  307 AAGNESAPSNVV-SVTTDLTPPAAPSGLTA--TAVGSSSITLSWT--ASSDADVTGYNVYRSTS-GGGTYTKIAETVTTT 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  367 SALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTskaDVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASPQ 446
Cdd:COG3401  381 SYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTAS---AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAV 457


                 ....*.
gi 63020636  447 GRNAKD 452
Cdd:COG3401  458 LADGGD 463
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 3-68 3.60e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.84  E-value: 3.60e-06
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63020636       3 LKVTWDPPKDATSR-PVEHYNIAYGKSLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVS 68
Cdd:smart00060   17 VTLSWEPPPDDGITgYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 211-284 1.39e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 44.91  E-value: 1.39e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63020636     211 PDDISVRVMSSQSVLVSWVDPVLEKQKKvvasrqYTVRYREKGELARWDYKQI----ANRRVLIENLIPDTVYEFAVR 284
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDGITG------YIVGYRVEYREEGSEWKEVnvtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 3-75 1.96e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.96e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 63020636    3 LKVTWDPPKDATSrPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVSRPVYRAE 75
Cdd:cd00063   17 VTLSWTPPEDDGG-PITGYVVEYREkgSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVT 90
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1594-1696 1.97e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 49.62  E-value: 1.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636 1594 DLPPQHAPRNITVVAVEGchSFVIVDWDKATPGDVvTGYLVYSASYEDFIRNKWSTQASSVTHLpIENLKPNTRYYFKVQ 1673
Cdd:COG3401  323 DLTPPAAPSGLTATAVGS--SSITLSWTASSDADV-TGYNVYRSTSGGGTYTKIAETVTTTSYT-DTGLTPGTTYYYKVT 398

                         90       100
                 ....*....|....*....|....
gi 63020636 1674 AQNPHG-YGPISPSVSFVTESDNP 1696
Cdd:COG3401  399 AVDAAGnESAPSEEVSATTASAAS 422
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
271-390 2.04e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 49.62  E-value: 2.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  271 ENLIPDTVYEFAVRISQGERDGKWSTSVFQRTPESAPtTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPA 350
Cdd:COG3401  197 GDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTA--TADTPGSVTLSWD--PVTESDATGYRVYRSNS 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 63020636  351 lkpfGAKSLTYPGDT--TSALVDGLQPGERYLFKIRATNRRG 390
Cdd:COG3401  272 ----GDGPFTKVATVttTSYTDTGLTNGTTYYYRVTAVDAAG 309
PHA03247 PHA03247
large tegument protein UL36; Provisional
 420-992 2.65e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 2.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   420 PEKPEPSSPSP-RAPASSQHPSVPASPQ-GRNAKDLLLDlknkilANGGAPRKPQLRakkaeeldlqsTEITGEEELGSR 497
Cdd:PHA03247 2484 AEARFPFAAGAaPDPGGGGPPDPDAPPApSRLAPAILPD------EPVGEPVHPRML-----------TWIRGLEELASD 2546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   498 ED-------SPMSPSDTQDQKRtlrPPSRHGHSVVAPGRTAvRARMPALPRREgvdkpgfslaTQPR-PGAPPSASASPA 569
Cdd:PHA03247 2547 DAgdpppplPPAAPPAAPDRSV---PPPRPAPRPSEPAVTS-RARRPDAPPQS----------ARPRaPVDDRGDPRGPA 2612

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   570 HHASTQGTSHRPSLPASLNDndlvdSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRS-SVHPGAKPASPARRT 648
Cdd:PHA03247 2613 PPSPLPPDTHAPDPPPPSPS-----PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRRRA 2687

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   649 PHSGAAEEDSSASAPPsrlsPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMsssvsshlssrTQVSEG 728
Cdd:PHA03247 2688 ARPTVGSLTSLADPPP----PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA-----------GPATPG 2752

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   729 AEASdgeshgdgdredggrqaeataqtlRARPASghfhllrhkPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHPR 808
Cdd:PHA03247 2753 GPAR------------------------PARPPT---------TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   809 VPSHSDSHPKLSSGIHGDEEDEK----PLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADT 884
Cdd:PHA03247 2800 SPWDPADPPAAVLAPAAALPPAAspagPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA 2879

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   885 HPqgKYSSLASKAqdVQQSTDadteghsPKAQPGStdrhaSPARPPAARSQQHPsvprrmtpgrapqqqPPPPVATSQHH 964
Cdd:PHA03247 2880 RP--PVRRLARPA--VSRSTE-------SFALPPD-----QPERPPQPQAPPPP---------------QPQPQPPPPPQ 2928

                         570       580
                  ....*....|....*....|....*...
gi 63020636   965 PGPQSRDAGRSPSQPRLSLTQAGRPRPT 992
Cdd:PHA03247 2929 PQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
220-416 3.05e-05

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 49.17  E-value: 3.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  220 SSQSVLVSWVDPVlekqkkvVASRqYTVRYREKGElaRWDYKQIANRRVLIENLIPDTVYEFAVR-ISQGERDGKWSTSV 298
Cdd:COG4733  550 AVTTLTVSWDAPA-------GAVA-YEVEWRRDDG--NWVSVPRTSGTSFEVPGIYAGDYEVRVRaINALGVSSAWAASS 619

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  299 -FQRTPESAPTTAPENLNVWPVNGKptvVAASWDALPETEgkVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGE 377
Cdd:COG4733  620 eTTVTGKTAPPPAPTGLTATGGLGG---ITLSWSFPVDAD--TLRTEIRYSTTGDWASATVAQALYPGNTYTLAGLKAGQ 694

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 63020636  378 RYLFKIRATNRRGLgpHSKAFIVAMPTTSKADVEQNTED 416
Cdd:COG4733  695 TYYYRARAVDRSGN--VSAWWVSGQASADAAGILDAITG 731
PHA03247 PHA03247
large tegument protein UL36; Provisional
 789-1224 3.77e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 3.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   789 PRLQPSSSPQSTVPSRAHPRVP--------SHSDSHPKLSSG-IHGDEEDEKPLPAtvvndhvPSSSRQPISRGWEDLRR 859
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSepavtsraRRPDAPPQSARPrAPVDDRGDPRGPA-------PPSPLPPDTHAPDPPPP 2629

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   860 SPQRGASLHRKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDAD--TEGHSPKAQPGSTDRHASPARPPAARSQQH 937
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASspPQRPRRRAARPTVGSLTSLADPPPPPPTPE 2709

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   938 PSvPRRMTPGRAPQQQPPPPVATSQHHP-GPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTAL 1016
Cdd:PHA03247 2710 PA-PHALVSATPLPPGPAAARQASPALPaAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAV 2788

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1017 QNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASL----PKHQQVESPTGAGAGGDHRSQRGHAAsparpsrPGGP 1092
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPlpppTSAQPTAPPPPPGPPPPSLPLGGSVA-------PGGD 2861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1093 QSRaRVPSRAAPGKSEPPSK-------RPLSSKSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADG 1165
Cdd:PHA03247 2862 VRR-RPPSRSPAAKPAAPARppvrrlaRPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 63020636  1166 SLAKEEREPAIALAPRGGSLAPVKRPLPPPPGSSPRaSHVPSRLPPRSAATVSPVAGTH 1224
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPR-FRVPQPAPSREAPASSTPPLTG 2998
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 535-930 3.12e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 3.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   535 RMPALPRREGVDKPGFSLATQPRPgappsasaspahhastqgtshRPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQP 614
Cdd:PHA03307   95 LAPASPAREGSPTPPGPSSPDPPP---------------------PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPP 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   615 RPALSPSRqspssvlrdrssvhPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKGGKD 694
Cdd:PHA03307  154 AAGASPAA--------------VASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASS 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   695 GEDAPATNSNAPsrstmsssvsshlssRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFA 774
Cdd:PHA03307  220 PAPAPGRSAADD---------------AGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGP 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   775 ANGRSPSRfsiGRGPRLQPSSSPQSTVPSRaHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPiSRGW 854
Cdd:PHA03307  285 ASSSSSPR---ERSPSPSPSSPGSGPAPSS-PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR-PPPP 359

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63020636   855 EDLRRSPQRGASlhrkEPIPENPKSTGADTHPQGKYSSLASKAqdVQQSTDADTEGHSPKAQPGSTDRHAS--PARPP 930
Cdd:PHA03307  360 ADPSSPRKRPRP----SRAPSSPAASAGRPTRRRARAAVAGRA--RRRDATGRFPAGRPRPSPLDAGAASGafYARYP 431
fn3 pfam00041
Fibronectin type III domain;
3-70 4.49e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.86  E-value: 4.49e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636      3 LKVTWDPPKDAtSRPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVSRP 70
Cdd:pfam00041   16 LTVSWTPPPDG-NGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 599-1042 8.78e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 8.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   599 ERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPAsPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLL 678
Cdd:PRK07764  391 AGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPA-PAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPA 469

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   679 PTQPHLSSPLSKGGKDGEDAPATnsnapsrstmsssvsshlssRTQVSEGAEASDGESHGDGDRE--DGGRQA--EATAQ 754
Cdd:PRK07764  470 PAAAPEPTAAPAPAPPAAPAPAA--------------------APAAPAAPAAPAGADDAATLRErwPEILAAvpKRSRK 529

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   755 TLRARPASGHFHLLR--------HKPFAANgrspsRFSIGRGPR-----LQPSSSPQSTVPSRAHPRVPSHSDSHPKLSS 821
Cdd:PRK07764  530 TWAILLPEATVLGVRgdtlvlgfSTGGLAR-----RFASPGNAEvlvtaLAEELGGDWQVEAVVGPAPGAAGGEGPPAPA 604

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   822 GIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASlhrKEPIPENPKSTGADTHPQGKYSSLASKAQDVQ 901
Cdd:PRK07764  605 SSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA---PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAP 681

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   902 QSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRmtpgrapqqqppppVATSQHHPGPQSRDAGRSPSQPRL 981
Cdd:PRK07764  682 PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ--------------AAQGASAPSPAADDPVPLPPEPDD 747

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 63020636   982 sltQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALqnqdEDAQGSYDDDSTEVEAQDVRAP 1042
Cdd:PRK07764  748 ---PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP----SEEEEMAEDDAPSMDDEDRRDA 801
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1596-1696 1.08e-03

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 43.84  E-value: 1.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636 1596 PPQhAPRNITVVAVEgcHSFVIVDWDKATPGDVvTGYLVYSASYEDfirNKWS----TQASSVTHlpiENLKPNTRYYFK 1671
Cdd:COG3401  232 PPS-APTGLTATADT--PGSVTLSWDPVTESDA-TGYRVYRSNSGD---GPFTkvatVTTTSYTD---TGLTNGTTYYYR 301

                         90       100
                 ....*....|....*....|....*.
gi 63020636 1672 VQAQNPHG-YGPISPSVSFVTESDNP 1696
Cdd:COG3401  302 VTAVDAAGnESAPSNVVSVTTDLTPP 327
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 915-1133 1.42e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   915 AQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQ 994
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   995 GrshsssDPYTASSRGMLPTALQNQDEDAQGsyDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHR 1074
Cdd:PRK07764  666 G------DGWPAKAGGAAPAAPPPAPAPAAP--AAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 63020636  1075 SQRGHAAsPARPSRPGGPQSRARVPSRAAPGKSEPPSKRPlSSKSQQSVSAEDDEEEDA 1133
Cdd:PRK07764  738 PVPLPPE-PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPP-SPPSEEEEMAEDDAPSMD 794
Pur_ac_phosph_N pfam16656
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ...
 1616-1691 2.64e-03

Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.


Pssm-ID: 465220 [Multi-domain]  Cd Length: 93  Bit Score: 38.93  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   1616 VIVDWdkATPGDVVTGYLVYSASYEDfirNKWSTQASSVT------------HLPIENLKPNTRYYFKVQAQNphgyGPI 1683
Cdd:pfam16656   15 MTVSW--VTPSAVTSPVVQYGTSSSA---LTSTATATSSTyttgdggtgyihRATLTGLEPGTTYYYRVGDDN----GGW 85


                   ....*...
gi 63020636   1684 SPSVSFVT 1691
Cdd:pfam16656   86 SEVYSFTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 106-192 4.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  106 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 182
Cdd:cd00063    1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76

                         90
                 ....*....|
gi 63020636  183 MNSQGRSQPV 192
Cdd:cd00063   77 VNGGGESPPS 86
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 913-1236 5.80e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 5.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   913 PKAQPGSTDRHASPARPPAAR---SQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRP 989
Cdd:PRK07764  413 AAAAPAAAAAPAPAAAPQPAPapaPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   990 RPTSQGRSHSSSDPYTA--------------------SSRGMLPTA--LQNQDE----------DAQGSYDDDSTEVEAQ 1037
Cdd:PRK07764  493 APAAPAAPAAPAGADDAatlrerwpeilaavpkrsrkTWAILLPEAtvLGVRGDtlvlgfstggLARRFASPGNAEVLVT 572

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1038 DVRApahaarakeaaaSLPKHQQVE-----SPTGAGAGGDHRSQRGHAAS----PARPSRPGGPQSRARVPSRAAPGKSE 1108
Cdd:PRK07764  573 ALAE------------ELGGDWQVEavvgpAPGAAGGEGPPAPASSGPPEeaarPAAPAAPAAPAAPAPAGAAAAPAEAS 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636  1109 PPSKRPLSSKSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPV 1188
Cdd:PRK07764  641 AAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQ 720

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 63020636  1189 KRPLPPPPGSSPRASHVPSRLPPrsAATVSPVAGTHPWPQYTTRAPPG 1236
Cdd:PRK07764  721 PPQAAQGASAPSPAADDPVPLPP--EPDDPPDPAGAPAQPPPPPAPAP 766
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
1600-1713 6.14e-03

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 40.91  E-value: 6.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636 1600 APRNITVVAVEGchSFVIVDWDKATPGDVVTGYLVYSASyedfirNKWSTQASSVTHLpIENLKPNTRYYFKVQAQNPHG 1679
Cdd:COG3979    5 APTGLTASNVTS--SSVSLSWDASTDNVGVTGYDVYRGG------DQVATVTGLTAWT-VTGLTPGTEYTFTVGACDAAG 75

                         90       100       110
                 ....*....|....*....|....*....|....
gi 63020636 1680 YGPISPSVSFVTESDNPLLVVRPPGGEPIWIPFA 1713
Cdd:COG3979   76 NVSAASGTSTAMFGGSSTTLGSAEGVADTSGNLA 109
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 524-760 6.59e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 6.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   524 VVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGappsasaspAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVG 603
Cdd:PRK07764  587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPA---------APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHV 657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   604 SLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPH 683
Cdd:PRK07764  658 AVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63020636   684 LSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEA--SDGESHGDGDREDGGRQA-EATAQTLRARP 760
Cdd:PRK07764  738 PVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMaeDDAPSMDDEDRRDAEEVAmELLEEELGAKK 817
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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