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Conserved domains on  [gi|45478168|gb|AAS66255|]
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LRRGT00164 [Rattus norvegicus]

Protein Classification

TPR and NatB_MDM20 domain-containing protein( domain architecture ID 11420853)

TPR and NatB_MDM20 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NatB_MDM20 pfam09797
N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit ...
 263-658 1.34e-159

N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyzes the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae this subunit is called MDM20 and in Schizosaccharomyces pombe it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1.


:

Pssm-ID: 430834  Cd Length: 368  Bit Score: 473.32  E-value: 1.34e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   263 WQFYLTYFDSVFRLIEEawtppaegehslegevHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDE 342
Cdd:pfam09797   1 WSVWKLYIDSTFKLIEA----------------KESLEEAQKFIEELIKAEEAKSPKSRNPYLARLELISRLRKRSDDAE 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   343 FRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLgvvpLSTPTEDKLAlPADIRGLQQHLCVVQLTR 422
Cdd:pfam09797  65 EDLGPLVELILEYFDKFGSKPCCFDDLKPYLELLSDEQRKEFLEKVS----PSKSELDSLV-PGDEKQLRRHINALKLSR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   423 LLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHS 502
Cdd:pfam09797 140 CLGLHSKLSEEEKEALVTELLAIYRAGLRLGASLLTTELQPSDDLALLAAHALLDLYRLTGDLTYLIQAILLLEFLLTKS 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   503 PSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYII 582
Cdd:pfam09797 220 PHNFQLKLLLVRLYLLLGAGSLALDLYSKLDIKQIQLDTLGHLLFTRLSTLGPFSLALNLLEQALRFYRNNEKETPEMIS 299

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 45478168   583 QAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTslaesikSMNLRPEEDDVPWEDLRDNRDL 658
Cdd:pfam09797 300 QAYEYGSYSKIEEFIEFRERLKNSLQRAMVRLERRRLDRLLGGDISD-------EMSLYPDEDRIDWSELSDNRDF 368
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-146 1.75e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.90  E-value: 1.75e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG4783  14 LLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKN 146
Cdd:COG4783  94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
 
Name Accession Description Interval E-value
NatB_MDM20 pfam09797
N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit ...
 263-658 1.34e-159

N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyzes the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae this subunit is called MDM20 and in Schizosaccharomyces pombe it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1.


Pssm-ID: 430834  Cd Length: 368  Bit Score: 473.32  E-value: 1.34e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   263 WQFYLTYFDSVFRLIEEawtppaegehslegevHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDE 342
Cdd:pfam09797   1 WSVWKLYIDSTFKLIEA----------------KESLEEAQKFIEELIKAEEAKSPKSRNPYLARLELISRLRKRSDDAE 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   343 FRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLgvvpLSTPTEDKLAlPADIRGLQQHLCVVQLTR 422
Cdd:pfam09797  65 EDLGPLVELILEYFDKFGSKPCCFDDLKPYLELLSDEQRKEFLEKVS----PSKSELDSLV-PGDEKQLRRHINALKLSR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   423 LLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHS 502
Cdd:pfam09797 140 CLGLHSKLSEEEKEALVTELLAIYRAGLRLGASLLTTELQPSDDLALLAAHALLDLYRLTGDLTYLIQAILLLEFLLTKS 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   503 PSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYII 582
Cdd:pfam09797 220 PHNFQLKLLLVRLYLLLGAGSLALDLYSKLDIKQIQLDTLGHLLFTRLSTLGPFSLALNLLEQALRFYRNNEKETPEMIS 299

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 45478168   583 QAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTslaesikSMNLRPEEDDVPWEDLRDNRDL 658
Cdd:pfam09797 300 QAYEYGSYSKIEEFIEFRERLKNSLQRAMVRLERRRLDRLLGGDISD-------EMSLYPDEDRIDWSELSDNRDF 368
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-146 1.75e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.90  E-value: 1.75e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG4783  14 LLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKN 146
Cdd:COG4783  94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 445-603 1.56e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 1.56e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 445 RYQHGLEFGRSCLKTELQFSDYYCLLAvhvliDIWREAGEETavwQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEP 524
Cdd:COG2956 125 DWEKAIEVLERLLKLGPENAHAYCELA-----ELYLEQGDYD---EAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 45478168 525 VVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQscnfALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRL 603
Cdd:COG2956 197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE----LLRKALELDPSDDLLLALADLLERKEGLEAALALLERQ 271
 
Name Accession Description Interval E-value
NatB_MDM20 pfam09797
N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit ...
 263-658 1.34e-159

N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyzes the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae this subunit is called MDM20 and in Schizosaccharomyces pombe it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1.


Pssm-ID: 430834  Cd Length: 368  Bit Score: 473.32  E-value: 1.34e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   263 WQFYLTYFDSVFRLIEEawtppaegehslegevHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDE 342
Cdd:pfam09797   1 WSVWKLYIDSTFKLIEA----------------KESLEEAQKFIEELIKAEEAKSPKSRNPYLARLELISRLRKRSDDAE 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   343 FRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLgvvpLSTPTEDKLAlPADIRGLQQHLCVVQLTR 422
Cdd:pfam09797  65 EDLGPLVELILEYFDKFGSKPCCFDDLKPYLELLSDEQRKEFLEKVS----PSKSELDSLV-PGDEKQLRRHINALKLSR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   423 LLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHS 502
Cdd:pfam09797 140 CLGLHSKLSEEEKEALVTELLAIYRAGLRLGASLLTTELQPSDDLALLAAHALLDLYRLTGDLTYLIQAILLLEFLLTKS 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   503 PSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYII 582
Cdd:pfam09797 220 PHNFQLKLLLVRLYLLLGAGSLALDLYSKLDIKQIQLDTLGHLLFTRLSTLGPFSLALNLLEQALRFYRNNEKETPEMIS 299

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 45478168   583 QAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTslaesikSMNLRPEEDDVPWEDLRDNRDL 658
Cdd:pfam09797 300 QAYEYGSYSKIEEFIEFRERLKNSLQRAMVRLERRRLDRLLGGDISD-------EMSLYPDEDRIDWSELSDNRDF 368
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-146 1.75e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.90  E-value: 1.75e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG4783  14 LLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKN 146
Cdd:COG4783  94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-160 7.43e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 7.43e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  13 RRLRPIYDYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREM 92
Cdd:COG3914  80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45478168  93 HRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQS 160
Cdd:COG3914 160 GRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQA 227
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 21-142 2.47e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 2.47e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG3914 122 LLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIA 201

                        90       100       110       120
                ....*....|....*....|....*....|....*....|..
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKI 142
Cdd:COG3914 202 AYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 21-220 2.52e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.36  E-value: 2.52e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG2956  52 YRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIE 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYfwsvmSLIMQSISARDENLSKtmflplAERM 180
Cdd:COG2956 132 VLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA-----LLLLAELYLEQGDYEE------AIAA 200

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 45478168 181 VEKMVKEDKIEAEAEVELYYmILERLGKYQEALDVIRGKL 220
Cdd:COG2956 201 LERALEQDPDYLPALPRLAE-LYEKLGDPEEALELLRKAL 239
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-156 2.26e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.17  E-value: 2.26e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG0457  18 YRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALE 97

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYkkmQQAGMALYKIVPKNPYYFWSVMSL 156
Cdd:COG0457  98 DYDKALELDPDDAEALYNLGLALLELGRY---DEAIEAYERALELDPDDADALYNL 150
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 20-220 3.19e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.89  E-value: 3.19e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  20 DYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVT 99
Cdd:COG2956  85 DYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 100 KLYEAAVKKVPNSEEYHSHLFMAYARVGEYkkmQQAGMALYKIVPKNPYYFwSVMSLIMQSISARDEnlsktmfLPLAER 179
Cdd:COG2956 165 EALEKALKLDPDCARALLLLAELYLEQGDY---EEAIAALERALEQDPDYL-PALPRLAELYEKLGD-------PEEALE 233

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 45478168 180 MVEKMVKEDkiEAEAEVELYYMILERLGKYQEALDVIRGKL 220
Cdd:COG2956 234 LLRKALELD--PSDDLLLALADLLERKEGLEAALALLERQL 272
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 30-147 1.41e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 1.41e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  30 AIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKV 109
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 45478168 110 PNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNP 147
Cdd:COG4235  82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-131 3.63e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 3.63e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG0457  52 YLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIE 131

                        90       100       110
                ....*....|....*....|....*....|.
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKK 131
Cdd:COG0457 132 AYERALELDPDDADALYNLGIALEKLGRYEE 162
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-217 1.03e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 1.03e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  51 KAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYk 130
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRY- 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 131 kmQQAGMALYKIVPKNPYYF--WSVMSLIMQSISARDEnlsktmflplAERMVEKMVKEDKIEAEAEVELyYMILERLGK 208
Cdd:COG0457  93 --EEALEDYDKALELDPDDAeaLYNLGLALLELGRYDE----------AIEAYERALELDPDDADALYNL-GIALEKLGR 159


                ....*....
gi 45478168 209 YQEALDVIR 217
Cdd:COG0457 160 YEEALELLE 168
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 47-151 1.15e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 1.15e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  47 AKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARV 126
Cdd:COG4783   6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                        90       100
                ....*....|....*....|....*....
gi 45478168 127 GEYKKmqqaGMALYKIV----PKNPYYFW 151
Cdd:COG4783  86 GDYDE----ALALLEKAlkldPEHPEAYL 110
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-217 1.21e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 1.21e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  50 LKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEY 129
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 130 KKMQQAGMALYKIVPKNPYYFWSVMslimqSISARDENLSKtmflplAERMVEKMVKEDKIEAEAEVELyYMILERLGKY 209
Cdd:COG2956  93 DRAEELLEKLLELDPDDAEALRLLA-----EIYEQEGDWEK------AIEVLERLLKLGPENAHAYCEL-AELYLEQGDY 160


                ....*...
gi 45478168 210 QEALDVIR 217
Cdd:COG2956 161 DEAIEALE 168
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 55-135 2.26e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 2.26e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  55 LQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQ 134
Cdd:COG5010  64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                .
gi 45478168 135 A 135
Cdd:COG5010 144 A 144
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 8-115 4.42e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 4.42e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   8 QDPND----RRLRPIYdyLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQ 83
Cdd:COG4235  12 ANPNDaegwLLLGRAY--LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALY 89

                        90       100       110
                ....*....|....*....|....*....|..
gi 45478168  84 ALTILYREMHRPELVTKLYEAAVKKVPNSEEY 115
Cdd:COG4235  90 LLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 63-151 3.05e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.53  E-value: 3.05e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  63 EAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKI 142
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                ....*....
gi 45478168 143 VPKNPYYFW 151
Cdd:COG4235  81 DPDNPEALY 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
55-145 4.69e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 4.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  55 LQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKlYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQ 134
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                        90
                ....*....|.
gi 45478168 135 AGMALYKIVPK 145
Cdd:COG3063  81 YLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 21-110 5.59e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 5.59e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG5010  64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                        90
                ....*....|
gi 45478168 101 LYEAAVKKVP 110
Cdd:COG5010 144 ALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
21-111 6.41e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 6.41e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLhcAKVLKAIG--LQRTGRQEEAFTLaQEVAALEPTDDNSLQALTILYREMHRPELV 98
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDN--ADALNNLGllLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEA 78

                        90
                ....*....|...
gi 45478168  99 TKLYEAAVKKVPN 111
Cdd:COG3063  79 LAYLERALELDPS 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-140 1.17e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.92  E-value: 1.17e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG0457  86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 45478168 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALY 140
Cdd:COG0457 166 LLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQ 205
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
73-217 1.30e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 1.30e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  73 ALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYfWS 152
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA-LN 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 45478168 153 VMSLIMQSISARDEnlsktmflplAERMVEKMVKEDKIEAEAeveLYY--MILERLGKYQEALDVIR 217
Cdd:COG0457  81 NLGLALQALGRYEE----------ALEDYDKALELDPDDAEA---LYNlgLALLELGRYDEAIEAYE 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 445-603 1.56e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 1.56e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 445 RYQHGLEFGRSCLKTELQFSDYYCLLAvhvliDIWREAGEETavwQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEP 524
Cdd:COG2956 125 DWEKAIEVLERLLKLGPENAHAYCELA-----ELYLEQGDYD---EAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 45478168 525 VVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQscnfALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRL 603
Cdd:COG2956 197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE----LLRKALELDPSDDLLLALADLLERKEGLEAALALLERQ 271
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 47-147 1.98e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 1.98e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168  47 AKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARV 126
Cdd:COG5010  22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS 101

                        90       100
                ....*....|....*....|.
gi 45478168 127 GEYKKMQQAGMALYKIVPKNP 147
Cdd:COG5010 102 GDKDEAKEYYEKALALSPDNP 122
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 445-568 2.83e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 2.83e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168 445 RYQHGLEFGRSCLKTELQFSDYYCLLAvhvliDIWREAGEETavwQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEP 524
Cdd:COG4783  19 DYDEAEALLEKALELDPDNPEAFALLG-----EILLQLGDLD---EAIVLLHEALELDPDEPEARLNLGLALLKAGDYDE 90

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 45478168 525 VVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALR 568
Cdd:COG4783  91 ALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 9-108 2.96e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 2.96e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45478168   9 DPNDRRLRPIYD--YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLqALT 86
Cdd:COG2956 174 DPDCARALLLLAelYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-ALA 252

                        90       100
                ....*....|....*....|..
gi 45478168  87 ILYREMHRPELVTKLYEAAVKK 108
Cdd:COG2956 253 DLLERKEGLEAALALLERQLRR 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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