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Conserved domains on  [gi|37993585|gb|AAR06891|]
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connexin 43, partial [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Connexin super family cl37952
Connexin; Connexin proteins form gap-junctions between cells. They carry four transmembrane ...
 3-29 1.53e-11

Connexin; Connexin proteins form gap-junctions between cells. They carry four transmembrane regions, hence why this family now includes Connexin_CCC, which represented the second pair of TMs.


The actual alignment was detected with superfamily member pfam00029:

Pssm-ID: 459638 [Multi-domain]  Cd Length: 217  Bit Score: 54.43  E-value: 1.53e-11
                          10        20
                  ....*....|....*....|....*..
gi 37993585     3 DWSALGKLLDKVQAYSTAGGKVWLSVL 29
Cdd:pfam00029   1 DWSFLGRLLEEVNKHSTVVGKIWLTVL 27
 
Name Accession Description Interval E-value
Connexin pfam00029
Connexin; Connexin proteins form gap-junctions between cells. They carry four transmembrane ...
 3-29 1.53e-11

Connexin; Connexin proteins form gap-junctions between cells. They carry four transmembrane regions, hence why this family now includes Connexin_CCC, which represented the second pair of TMs.


Pssm-ID: 459638 [Multi-domain]  Cd Length: 217  Bit Score: 54.43  E-value: 1.53e-11
                          10        20
                  ....*....|....*....|....*..
gi 37993585     3 DWSALGKLLDKVQAYSTAGGKVWLSVL 29
Cdd:pfam00029   1 DWSFLGRLLEEVNKHSTVVGKIWLTVL 27
 
Name Accession Description Interval E-value
Connexin pfam00029
Connexin; Connexin proteins form gap-junctions between cells. They carry four transmembrane ...
 3-29 1.53e-11

Connexin; Connexin proteins form gap-junctions between cells. They carry four transmembrane regions, hence why this family now includes Connexin_CCC, which represented the second pair of TMs.


Pssm-ID: 459638 [Multi-domain]  Cd Length: 217  Bit Score: 54.43  E-value: 1.53e-11
                          10        20
                  ....*....|....*....|....*..
gi 37993585     3 DWSALGKLLDKVQAYSTAGGKVWLSVL 29
Cdd:pfam00029   1 DWSFLGRLLEEVNKHSTVVGKIWLTVL 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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