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Conserved domains on  [gi|28973181|gb|AAO63915|]
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unknown protein [Arabidopsis thaliana]

Protein Classification

purine permease( domain architecture ID 12180965)

purine permease is a proton-coupled transporter that mediates the uptake of nucleosides, nucleotides, and their derivatives, such as adenine and cytosine, as well as purine derivatives (hypoxanthine), phytohormones (zeatin and kinetin), and alkaloids (caffeine and nicotine)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
26-337 8.22e-116

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


:

Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 339.64  E-value: 8.22e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181    26 TLLIVTYFFLFFGSIASSLLAKYYFVYGGSSRWVSTWVQSAGFPLLLILIYFPHYVLKTTT-RRPFTRFTLRHLIFSVLI 104
Cdd:pfam16913   1 ILVIISIFFLLIGQAISTLLGRLYFVNGGKSTWLQTLVQTAGFPLLLLPLLFSFLSKKRNQeTTSFSSSFKRLVIIYIVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181   105 GLVLGFNNFLFSWGTSYLPVSTSSLLLSTQLVFTLILSRIIVKQKITFSNLNCVVLLTLSSVLLALDSSKDKPSGLTKTK 184
Cdd:pfam16913  81 GLLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVVLLTISAALLALDSSSDKPSGESKKK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181   185 YFIGYVSTIGAGLLFALYLPVTEKLYRTVYC---YAMVMEVQLVMEFAATVFATIGMACEGGFKEMVKEANHvFTKGPTF 261
Cdd:pfam16913 161 YVIGFWCTIGASALFSLILCLVELAFEKVLKrrtFSMVLEMQIVMSLVATCVCVIGLFASGEFKDLKGEMEE-FKKGKSL 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28973181   262 YwTFAILANVVTWQLSFAATSGMVYLTSGITGGICMTALLAMNVIGGVVAYGDVFGGVKIVSTVLCIWGFSSYTYG 337
Cdd:pfam16913 240 Y-VLTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFASYFYG 314
 
Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
26-337 8.22e-116

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 339.64  E-value: 8.22e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181    26 TLLIVTYFFLFFGSIASSLLAKYYFVYGGSSRWVSTWVQSAGFPLLLILIYFPHYVLKTTT-RRPFTRFTLRHLIFSVLI 104
Cdd:pfam16913   1 ILVIISIFFLLIGQAISTLLGRLYFVNGGKSTWLQTLVQTAGFPLLLLPLLFSFLSKKRNQeTTSFSSSFKRLVIIYIVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181   105 GLVLGFNNFLFSWGTSYLPVSTSSLLLSTQLVFTLILSRIIVKQKITFSNLNCVVLLTLSSVLLALDSSKDKPSGLTKTK 184
Cdd:pfam16913  81 GLLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVVLLTISAALLALDSSSDKPSGESKKK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181   185 YFIGYVSTIGAGLLFALYLPVTEKLYRTVYC---YAMVMEVQLVMEFAATVFATIGMACEGGFKEMVKEANHvFTKGPTF 261
Cdd:pfam16913 161 YVIGFWCTIGASALFSLILCLVELAFEKVLKrrtFSMVLEMQIVMSLVATCVCVIGLFASGEFKDLKGEMEE-FKKGKSL 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28973181   262 YwTFAILANVVTWQLSFAATSGMVYLTSGITGGICMTALLAMNVIGGVVAYGDVFGGVKIVSTVLCIWGFSSYTYG 337
Cdd:pfam16913 240 Y-VLTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFASYFYG 314
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
58-151 1.13e-05

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 46.76  E-value: 1.13e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181  58 WVSTWVQSAGFPLLLILIYFphyvlkttTRRPFTRFTLRHLIFSVLIGLVLGF-NNFLFSWGTSYLPVSTSSLLLSTQLV 136
Cdd:COG0697  33 QLAFLRFLLAALLLLPLLLL--------RGRRLPPLSRRDWLLLLLRGLLGLAlAFLLFFLALQYTPAALAALLLALAPL 104
                        90
                ....*....|....*
gi 28973181 137 FTLILSRIIVKQKIT 151
Cdd:COG0697 105 FVALLAALLLGERLS 119
 
Name Accession Description Interval E-value
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
26-337 8.22e-116

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 339.64  E-value: 8.22e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181    26 TLLIVTYFFLFFGSIASSLLAKYYFVYGGSSRWVSTWVQSAGFPLLLILIYFPHYVLKTTT-RRPFTRFTLRHLIFSVLI 104
Cdd:pfam16913   1 ILVIISIFFLLIGQAISTLLGRLYFVNGGKSTWLQTLVQTAGFPLLLLPLLFSFLSKKRNQeTTSFSSSFKRLVIIYIVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181   105 GLVLGFNNFLFSWGTSYLPVSTSSLLLSTQLVFTLILSRIIVKQKITFSNLNCVVLLTLSSVLLALDSSKDKPSGLTKTK 184
Cdd:pfam16913  81 GLLVGADNFLYSYGLLYLPVSTFSLILATQLAFTAIFSYFINKQKFTPFIINSVVLLTISAALLALDSSSDKPSGESKKK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181   185 YFIGYVSTIGAGLLFALYLPVTEKLYRTVYC---YAMVMEVQLVMEFAATVFATIGMACEGGFKEMVKEANHvFTKGPTF 261
Cdd:pfam16913 161 YVIGFWCTIGASALFSLILCLVELAFEKVLKrrtFSMVLEMQIVMSLVATCVCVIGLFASGEFKDLKGEMEE-FKKGKSL 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28973181   262 YwTFAILANVVTWQLSFAATSGMVYLTSGITGGICMTALLAMNVIGGVVAYGDVFGGVKIVSTVLCIWGFSSYTYG 337
Cdd:pfam16913 240 Y-VLTLVGTAVSWQVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFASYFYG 314
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
58-151 1.13e-05

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 46.76  E-value: 1.13e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181  58 WVSTWVQSAGFPLLLILIYFphyvlkttTRRPFTRFTLRHLIFSVLIGLVLGF-NNFLFSWGTSYLPVSTSSLLLSTQLV 136
Cdd:COG0697  33 QLAFLRFLLAALLLLPLLLL--------RGRRLPPLSRRDWLLLLLRGLLGLAlAFLLFFLALQYTPAALAALLLALAPL 104
                        90
                ....*....|....*
gi 28973181 137 FTLILSRIIVKQKIT 151
Cdd:COG0697 105 FVALLAALLLGERLS 119
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
55-153 2.32e-04

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 40.64  E-value: 2.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28973181    55 SSRWVSTWVQSAGFPLLLILIYFphyvlkTTTRRPFTRFTLRHLIFSVLIGLVLGFnnFLFSWGTSYLPVSTSSLLLSTQ 134
Cdd:pfam00892  29 SPLTLTFWRFLIAGILLLPFALF------TGGKLVIPLKSWLALLYLGVLGTFLGF--LLYFYGLKYVSASNASVITSLS 100
                          90
                  ....*....|....*....
gi 28973181   135 LVFTLILSRIIVKQKITFS 153
Cdd:pfam00892 101 PVFTLILSVLLLGEKLTLK 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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