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Conserved domains on  [gi|25082851|gb|AAN72007|]
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putative protein [Arabidopsis thaliana]

Protein Classification

TIC20 domain-containing protein( domain architecture ID 11241249)

TIC20 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TIC20 pfam16166
Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear ...
 43-204 3.73e-59

Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.


:

Pssm-ID: 374405  Cd Length: 177  Bit Score: 183.37  E-value: 3.73e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851    43 RAATLVLQSKGDDSVDASD------------RIISAVCYFYPFFDGIQYGKF------IITQYQPFQILIQPLFPAIRAF 104
Cdd:pfam16166   1 RRPTTLCRSASKDSLSAFDfpelaekpewwwRTLSCVPYLLPLFNGWQYGDTgyylhpFLEQFPPFGLLIYPIPGAINRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851   105 KSFpfNGFLIFITLYFVVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRDGFGLDVVMSLDSTVFLFLLVSLIY 184
Cdd:pfam16166  81 PSW--FSMVYFFTLYFGVVRNKNLPHYFRFHVMMAMLLDVLLQV-VLLTSNFNPLIGFGGKFGMYYWTGVFLFYIFTLLY 157

                         170       180
                  ....*....|....*....|
gi 25082851   185 GFSACLFGLTPRLPLVAEAA 204
Cdd:pfam16166 158 CIRCALAGMYPRIPFVSEAA 177
 
Name Accession Description Interval E-value
TIC20 pfam16166
Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear ...
 43-204 3.73e-59

Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.


Pssm-ID: 374405  Cd Length: 177  Bit Score: 183.37  E-value: 3.73e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851    43 RAATLVLQSKGDDSVDASD------------RIISAVCYFYPFFDGIQYGKF------IITQYQPFQILIQPLFPAIRAF 104
Cdd:pfam16166   1 RRPTTLCRSASKDSLSAFDfpelaekpewwwRTLSCVPYLLPLFNGWQYGDTgyylhpFLEQFPPFGLLIYPIPGAINRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851   105 KSFpfNGFLIFITLYFVVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRDGFGLDVVMSLDSTVFLFLLVSLIY 184
Cdd:pfam16166  81 PSW--FSMVYFFTLYFGVVRNKNLPHYFRFHVMMAMLLDVLLQV-VLLTSNFNPLIGFGGKFGMYYWTGVFLFYIFTLLY 157

                         170       180
                  ....*....|....*....|
gi 25082851   185 GFSACLFGLTPRLPLVAEAA 204
Cdd:pfam16166 158 CIRCALAGMYPRIPFVSEAA 177
Tic20 COG5769
Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein ...
 56-208 2.01e-32

Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein import [Energy production and conversion];


Pssm-ID: 444479  Cd Length: 159  Bit Score: 114.60  E-value: 2.01e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851  56 SVDASDRIISAVCYFYPFFDGIQYGKFIITQYQPFQILIQPLFPAIRAFKSFPFNGFLIFITLYFVVVRNPNFSRYVRFN 135
Cdd:COG5769   6 STTVKDRIFAALPYLLPLIDALPFGIFLFRQFPLLQILYLPLLPLIQIYYGIPFAGLIIFFVLFLAVVRNEKISHFIRFN 85

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25082851 136 TMQAIVLDVLLIFPDLLERSFNPRDGFGLDVVMSLDSTVFLFLLVSLIYGFSACLFGLTPRLPLVAEAADRQV 208
Cdd:COG5769  86 TMQAILLDILLILCGLVLQILGQGIPGGGLLIETLSNTIFLGTLAAVVYSIVQSLRGRYAEIPTISEAVYMQV 158
 
Name Accession Description Interval E-value
TIC20 pfam16166
Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear ...
 43-204 3.73e-59

Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.


Pssm-ID: 374405  Cd Length: 177  Bit Score: 183.37  E-value: 3.73e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851    43 RAATLVLQSKGDDSVDASD------------RIISAVCYFYPFFDGIQYGKF------IITQYQPFQILIQPLFPAIRAF 104
Cdd:pfam16166   1 RRPTTLCRSASKDSLSAFDfpelaekpewwwRTLSCVPYLLPLFNGWQYGDTgyylhpFLEQFPPFGLLIYPIPGAINRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851   105 KSFpfNGFLIFITLYFVVVRNPNFSRYVRFNTMQAIVLDVLLIFpDLLERSFNPRDGFGLDVVMSLDSTVFLFLLVSLIY 184
Cdd:pfam16166  81 PSW--FSMVYFFTLYFGVVRNKNLPHYFRFHVMMAMLLDVLLQV-VLLTSNFNPLIGFGGKFGMYYWTGVFLFYIFTLLY 157

                         170       180
                  ....*....|....*....|
gi 25082851   185 GFSACLFGLTPRLPLVAEAA 204
Cdd:pfam16166 158 CIRCALAGMYPRIPFVSEAA 177
Tic20 COG5769
Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein ...
 56-208 2.01e-32

Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein import [Energy production and conversion];


Pssm-ID: 444479  Cd Length: 159  Bit Score: 114.60  E-value: 2.01e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25082851  56 SVDASDRIISAVCYFYPFFDGIQYGKFIITQYQPFQILIQPLFPAIRAFKSFPFNGFLIFITLYFVVVRNPNFSRYVRFN 135
Cdd:COG5769   6 STTVKDRIFAALPYLLPLIDALPFGIFLFRQFPLLQILYLPLLPLIQIYYGIPFAGLIIFFVLFLAVVRNEKISHFIRFN 85

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25082851 136 TMQAIVLDVLLIFPDLLERSFNPRDGFGLDVVMSLDSTVFLFLLVSLIYGFSACLFGLTPRLPLVAEAADRQV 208
Cdd:COG5769  86 TMQAILLDILLILCGLVLQILGQGIPGGGLLIETLSNTIFLGTLAAVVYSIVQSLRGRYAEIPTISEAVYMQV 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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