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Concise Results
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RE74040p [Drosophila melanogaster]
Protein Classification
alanine--tRNA ligase ( domain architecture ID 1001926 )
alanine--tRNA ligase catalyzes the attachment of alanine to the 3' OH group of ribose of tRNA(Ala)
List of domain hits
Name
Accession
Description
Interval
E-value
PLN02900 super family
cl33594 alanyl-tRNA synthetase
13-1010
0e+00
alanyl-tRNA synthetase
PLN02900 :Pssm-ID: 215487 [Multi-domain]
Cd Length: 936
Bit Score: 656.70
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 13 TARE IR K TFL DH F t VNH GH K F VR SSP V VP FC DPT VA F V NAGMNQFK SV FLGTA A ----- APHK R VV N S QKC V R V GGKHND 87
Cdd:PLN02900 12 PGDR IR R TFL SF F - ESK GH T F LP SSP L VP VD DPT LL F T NAGMNQFK PI FLGTA D pntpl RKLP R AT N T QKC I R A GGKHND 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 88 L SV VG T D G YHHTFFEMLGNWSFGDYFK R EA CAM A L ELL RGP Y NIDPG RLY V TYF A GD KVL gi PA D L E CFE IW RSL g F P AS 167
Cdd:PLN02900 91 L DD VG K D T YHHTFFEMLGNWSFGDYFK K EA IGW A W ELL TKV Y GLPAD RLY A TYF G GD EKQ -- AP D D E ARA IW LDY - L P EE 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 168 R I LPFGC A DNFWEMG A TGPCGPC T EIH I D HRPDLGS veqr A K LVN AGRSDLT E L WNLVFIQ Y NR H ADGS ISQ LPA H HVDT 247
Cdd:PLN02900 168 R V LPFGC K DNFWEMG D TGPCGPC S EIH Y D RIGERDA ---- A D LVN NDDPRFI E I WNLVFIQ F NR E ADGS LKP LPA K HVDT 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 248 GMG F ERL TAV LQNK S SNYDTDLF T PIFD G IQ Q A AKTPV Y S G SFPDGGNAA V l D TS YR IL ADH A R MVTACL ADG ML P D --- 324
Cdd:PLN02900 244 GMG L ERL ASI LQNK P SNYDTDLF M PIFD A IQ E A TGARP Y A G KVGAEDDDR V - D MA YR VV ADH I R TLSFAI ADG VV P S neg 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 325 QNQK LRR V LR K A ------- L NIS E HV F A hdkllt Q LV PI VVE TL G EAY PE MAAKQQAVIDL I CH E QEVYKNLR E SSSKA F 397
Cdd:PLN02900 323 RGYV LRR L LR R A vrygrll L GAE E GF F P ------ A LV EV VVE LS G DVF PE VKKNEKRITEI I AE E ELSFGKTL E KGIEK F 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 398 AEV L MEFPNLDD idlmecpgfvpayrelqmqrckfsn NTIP G DFLYK L T DTYG ---- LTE E sflk L AE LENMNC D L E RYR 473
Cdd:PLN02900 397 KKA L AAAKANGG ------------------------- PVLS G KDAFL L Y DTYG fpvd LTE L ---- M AE ERGVTV D M E GFE 447
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 474 A EVSL A KLKAK g NQRET AGG SLCD LA teqri AEA QAM L T K R - LTP TD NSH KY TY sf DKESDS yqipplkt R V LGM L LNDA 552
Cdd:PLN02900 448 A AMEE A RERSR - AAHLK AGG GAIE LA ----- AEA TSW L Q K Q g VAA TD DFL KY DW -- LSDHEA -------- V V KAI L TGGG 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 553 E V SRTQGS riqqpft D LIS IV TAGSN FY Y ESGGQ QS D G G KILV S NHQ qpdhph SLD V IG V KHLNDC V V HI CKLSSPT daf 632
Cdd:PLN02900 512 F V ESVSEG ------- D EVG IV LDKTS FY A ESGGQ IG D T G VLEG S GGA ------ VVE V SD V QKAGGF V L HI GTVTEGS --- 575
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 633 q LAI GD E V ELQ VD AQQ R QLNTCH HTATHLLN A A IRSLFKKVTY Q VS S S V SSDQCKLELG l L GK RIQKTDVQLI E D L I N RV 712
Cdd:PLN02900 576 - VSV GD A V TCK VD YDR R RRIAPN HTATHLLN S A LKEVLGDHVD Q KG S L V AFEKLRFDFS - H GK PMTPEELREV E S L V N EW 653
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 713 I CS A A PVE VQLLSA A EVLEQ N DITM V P GE V YP EQ g L R L V N V E spel QLS S K ELC C GTH AT NT S E LSC F CIVN ---- L K QT 788
Cdd:PLN02900 654 I GD A L PVE AKEMPL A DAKRI N GLRA V F GE K YP DP - V R V V S V G ---- GVY S M ELC G GTH VS NT A E AEA F KLLS eegi A K GI 728
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 789 N R arfa F TAV A G Q AA ENVLKT A AL L RHRV D llekqf QTD K LTNAT - E AELQTIRHNMLHTD I kl P Y A F K MDTLE R ITEML 867
Cdd:PLN02900 729 R R ---- I TAV T G G AA VEAINA A DS L EREL D ------ SAL K VEGSD l E KKVASLKSRVDAAV I -- P A A K K EEIRA R VSALQ 796
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 868 K RIKDSSRTTLKEFVD -- V EMR T L L QE K P L DTHP filhyits S A LV EEIP ------- L QR A T ---- KLCP D RPIL V I S VC 934
Cdd:PLN02900 797 K ELRAAQKEAAALRAK la V AKA T E L AS K A L SAGK -------- S V LV ARLD vgvdaaa L KE A A ekvi AKLG D PAAV V L S SD 868
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25012817 935 DSVV K ARCC -- VP EKCITEKFN A SA WL QSF A DT f N G QIAAP K GQNP Q A vcnm K GR RV snlfe E Q L EQ A MS KA H A Y A KL 1010
Cdd:PLN02900 869 EEKG K VSLV aa VP PGVVKKGLK A GK WL GAI A KL - C G GGGGG K PGFA Q G ---- Q GR DA ----- E K L DA A LE KA R A F A VA 936
Name
Accession
Description
Interval
E-value
PLN02900
PLN02900 alanyl-tRNA synthetase
13-1010
0e+00
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain]
Cd Length: 936
Bit Score: 656.70
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 13 TARE IR K TFL DH F t VNH GH K F VR SSP V VP FC DPT VA F V NAGMNQFK SV FLGTA A ----- APHK R VV N S QKC V R V GGKHND 87
Cdd:PLN02900 12 PGDR IR R TFL SF F - ESK GH T F LP SSP L VP VD DPT LL F T NAGMNQFK PI FLGTA D pntpl RKLP R AT N T QKC I R A GGKHND 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 88 L SV VG T D G YHHTFFEMLGNWSFGDYFK R EA CAM A L ELL RGP Y NIDPG RLY V TYF A GD KVL gi PA D L E CFE IW RSL g F P AS 167
Cdd:PLN02900 91 L DD VG K D T YHHTFFEMLGNWSFGDYFK K EA IGW A W ELL TKV Y GLPAD RLY A TYF G GD EKQ -- AP D D E ARA IW LDY - L P EE 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 168 R I LPFGC A DNFWEMG A TGPCGPC T EIH I D HRPDLGS veqr A K LVN AGRSDLT E L WNLVFIQ Y NR H ADGS ISQ LPA H HVDT 247
Cdd:PLN02900 168 R V LPFGC K DNFWEMG D TGPCGPC S EIH Y D RIGERDA ---- A D LVN NDDPRFI E I WNLVFIQ F NR E ADGS LKP LPA K HVDT 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 248 GMG F ERL TAV LQNK S SNYDTDLF T PIFD G IQ Q A AKTPV Y S G SFPDGGNAA V l D TS YR IL ADH A R MVTACL ADG ML P D --- 324
Cdd:PLN02900 244 GMG L ERL ASI LQNK P SNYDTDLF M PIFD A IQ E A TGARP Y A G KVGAEDDDR V - D MA YR VV ADH I R TLSFAI ADG VV P S neg 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 325 QNQK LRR V LR K A ------- L NIS E HV F A hdkllt Q LV PI VVE TL G EAY PE MAAKQQAVIDL I CH E QEVYKNLR E SSSKA F 397
Cdd:PLN02900 323 RGYV LRR L LR R A vrygrll L GAE E GF F P ------ A LV EV VVE LS G DVF PE VKKNEKRITEI I AE E ELSFGKTL E KGIEK F 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 398 AEV L MEFPNLDD idlmecpgfvpayrelqmqrckfsn NTIP G DFLYK L T DTYG ---- LTE E sflk L AE LENMNC D L E RYR 473
Cdd:PLN02900 397 KKA L AAAKANGG ------------------------- PVLS G KDAFL L Y DTYG fpvd LTE L ---- M AE ERGVTV D M E GFE 447
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 474 A EVSL A KLKAK g NQRET AGG SLCD LA teqri AEA QAM L T K R - LTP TD NSH KY TY sf DKESDS yqipplkt R V LGM L LNDA 552
Cdd:PLN02900 448 A AMEE A RERSR - AAHLK AGG GAIE LA ----- AEA TSW L Q K Q g VAA TD DFL KY DW -- LSDHEA -------- V V KAI L TGGG 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 553 E V SRTQGS riqqpft D LIS IV TAGSN FY Y ESGGQ QS D G G KILV S NHQ qpdhph SLD V IG V KHLNDC V V HI CKLSSPT daf 632
Cdd:PLN02900 512 F V ESVSEG ------- D EVG IV LDKTS FY A ESGGQ IG D T G VLEG S GGA ------ VVE V SD V QKAGGF V L HI GTVTEGS --- 575
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 633 q LAI GD E V ELQ VD AQQ R QLNTCH HTATHLLN A A IRSLFKKVTY Q VS S S V SSDQCKLELG l L GK RIQKTDVQLI E D L I N RV 712
Cdd:PLN02900 576 - VSV GD A V TCK VD YDR R RRIAPN HTATHLLN S A LKEVLGDHVD Q KG S L V AFEKLRFDFS - H GK PMTPEELREV E S L V N EW 653
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 713 I CS A A PVE VQLLSA A EVLEQ N DITM V P GE V YP EQ g L R L V N V E spel QLS S K ELC C GTH AT NT S E LSC F CIVN ---- L K QT 788
Cdd:PLN02900 654 I GD A L PVE AKEMPL A DAKRI N GLRA V F GE K YP DP - V R V V S V G ---- GVY S M ELC G GTH VS NT A E AEA F KLLS eegi A K GI 728
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 789 N R arfa F TAV A G Q AA ENVLKT A AL L RHRV D llekqf QTD K LTNAT - E AELQTIRHNMLHTD I kl P Y A F K MDTLE R ITEML 867
Cdd:PLN02900 729 R R ---- I TAV T G G AA VEAINA A DS L EREL D ------ SAL K VEGSD l E KKVASLKSRVDAAV I -- P A A K K EEIRA R VSALQ 796
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 868 K RIKDSSRTTLKEFVD -- V EMR T L L QE K P L DTHP filhyits S A LV EEIP ------- L QR A T ---- KLCP D RPIL V I S VC 934
Cdd:PLN02900 797 K ELRAAQKEAAALRAK la V AKA T E L AS K A L SAGK -------- S V LV ARLD vgvdaaa L KE A A ekvi AKLG D PAAV V L S SD 868
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25012817 935 DSVV K ARCC -- VP EKCITEKFN A SA WL QSF A DT f N G QIAAP K GQNP Q A vcnm K GR RV snlfe E Q L EQ A MS KA H A Y A KL 1010
Cdd:PLN02900 869 EEKG K VSLV aa VP PGVVKKGLK A GK WL GAI A KL - C G GGGGG K PGFA Q G ---- Q GR DA ----- E K L DA A LE KA R A F A VA 936
AlaS
COG0013 Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ...
12-783
0e+00
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain]
Cd Length: 880
Bit Score: 618.22
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 12 L T AR EIR KT FLD H F t VNH GH KF V R SS PV VP FC DPT VA F V NAGM N QFK SV FLG TAAA P HK R VVN SQKCVR V GGKHNDL SV V 91
Cdd:COG0013 2 M T SA EIR QK FLD F F - ESK GH TI V P SS SL VP KN DPT LL F T NAGM V QFK PY FLG QEKP P YP R ATT SQKCVR T GGKHNDL EN V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 92 G TDGY HHTFFEMLGN W SFGDYFK R EA C A M A L ELL RGPYNIDPG RL Y VT YFAG D K vlgipadl E CFE IW RSL - G F P AS RI L 170
Cdd:COG0013 81 G YTAR HHTFFEMLGN F SFGDYFK E EA I A W A W ELL TEVLGLPKE RL W VT VYED D D -------- E AYD IW KKE i G V P EE RI I 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 171 PF G CA DNFWEMG A TGPCGPC T EI HI D HR P DL G SVEQRAKLVNAG R sd LT E L WNLVF I Q Y NR HA DG SISQ LP AHHV DTGMG 250
Cdd:COG0013 153 RL G KK DNFWEMG D TGPCGPC S EI FY D RG P EY G GGPPGSPGEDGD R -- YI E I WNLVF M Q F NR DE DG TLTP LP KKNI DTGMG 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 251 F ER LT AVLQ NKS SNY D TDLF T P IFDGIQQAAKTP v Y SGSFP D ggnaavl D T S Y R IL ADH A R M V TACL ADG M LP D q N QK -- 328
Cdd:COG0013 231 L ER IA AVLQ GVH SNY E TDLF R P LIEAAAELTGVK - Y GADEE D ------- D V S L R VI ADH I R A V AFLI ADG V LP S - N EG rg 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 329 -- LRR V LR K A ------ L N I S E HVFA hdkllt Q LVP I VVE TL G E AYPE MAA KQ QAVIDLICH E Q E vyknlresssk A F AEV 400
Cdd:COG0013 302 yv LRR I LR R A vrhgrl L G I K E PFLY ------ K LVP V VVE EM G D AYPE LKE KQ ELIEKVLKA E E E ----------- R F LRT 364
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 401 L --- MEF pn LD DI dl ME cpgfvpayr E L Q mqrc KFSNNTIP G DFLY KL T DTYG ---- LTEE sflk L A ELENMNC D L E RYR 473
Cdd:COG0013 365 L erg LKL -- LD EA -- IA --------- K L K ---- AAGGKVLS G EDAF KL Y DTYG fpld LTEE ---- I A RERGLTV D E E GFE 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 474 A EVSLAKLK A KGNQRETAGGSLCDLAT E qriaeaqam L TKRLT PT D nshkytys F --- D KESD syqippl KTR VL GMLLN 550
Cdd:COG0013 424 A AMEEQRER A RAAAKFSGDAAVDGVWR E --------- L LEEGG PT E -------- F vgy D TLEA ------- EAK VL ALVKD 479
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 551 DAE V SR - TQ G SRIQ qpftdlis I V TAGSN FY Y ESGGQ QS D G G K I LVSNHQ qpdhphs LD V IGV - K HLNDCV VHI C K LSSP 628
Cdd:COG0013 480 GEL V DS a KA G EEVE -------- V V LDRTP FY A ESGGQ VG D T G T I EGDGGV ------- FE V TDT q K PPGGLI VHI G K VEEG 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 629 T dafq L AI GD E V EL QVDA QQ R QLNTCH H T ATHLL N AA I R ----------- SL ------------ F KKV T yqvsssvssdq 685
Cdd:COG0013 545 E ---- L KV GD T V TA QVDA ER R RAIARN H S ATHLL H AA L R evlgehvtqag SL vapdrlrfdfsh F EAL T ----------- 609
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 686 cklelgllgkriq KTDVQL IEDL I N RV I CSAA PVE VQLLSAA E VLEQNDITMV p GE V Y PEQ g L R L V NVESP elqls S K EL 765
Cdd:COG0013 610 ------------- PEELAE IEDL V N EK I RENL PVE TREMPLD E AKALGAMALF - GE K Y GDE - V R V V SIGDF ----- S R EL 669
810
....*....|....*...
gi 25012817 766 C C GTH ATN T SELSC F C IV 783
Cdd:COG0013 670 C G GTH VSR T GDIGL F K IV 687
tRNA-synt_2c
pfam01411 tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ...
16-645
3.80e-161
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain]
Cd Length: 548
Bit Score: 485.63
E-value: 3.80e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 16 EIR K TFLD H F t VNH GH KF V R SSPVVP FC DPT VA F V NAGMNQFK SV FLG TA A - A P HK R VV NSQKC V R V G gkhn DL SV VG TD 94
Cdd:pfam01411 1 EIR Q TFLD F F - EKK GH TR V P SSPVVP RN DPT LL F T NAGMNQFK PI FLG GV A k P P YN R AT NSQKC I R A G ---- DL EN VG RT 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 95 G Y HHTFFEMLGN W SFGDYFK R EA CAM A L ELL RGPYNID P G RLYVT Y F AG D K vlgipadl E CFE IW RSL - G F P AS RIL P FG 173
Cdd:pfam01411 76 G R HHTFFEMLGN F SFGDYFK E EA IEY A W ELL TKELGLP P E RLYVT V F EW D D -------- E AGP IW EKI v G G P EE RIL R FG 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 174 CA DNFWEMG A TGPCGPC T EI HI D HRPDL G s VEQRAKLVN A GRSDLT E L WNLVF I Q Y NR HA DG SISQ LP AHHV DTGMG F ER 253
Cdd:pfam01411 148 DK DNFWEMG D TGPCGPC S EI DY D RGEEI G - GWDSGGTPT A DDDRFL E I WNLVF M Q F NR EN DG TLKP LP KKSI DTGMG L ER 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 254 L T AVLQ NKS SNYDTD L F T P IFDG I QQAAKTPV Y S gsfpdggn AAVL D TS YR IL ADH A R MV T AC LADG ML P D q N QK ---- L 329
Cdd:pfam01411 227 L V AVLQ DVR SNYDTD V F I P VIEL I EEISGARY Y T -------- VDET D EA YR VI ADH T R AL T FA LADG VV P S - N EG rgyv L 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 330 RR V LR K A LNISEHVFAHDKL L TQ LVP I VVE T LG E AYPE MAAKQQAVIDLICH E Q E VYKNLR E SSSKAFAEVL mefpnldd 409
Cdd:pfam01411 298 RR I LR R A VRHAKKLGLKEPF L YD LVP T VVE V LG D AYPE LKEDEDFIQEILEL E E E RFAKTL E RGLRLLERLI -------- 369
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 410 idlmecpgfvpayrelqm QRC K FSNN T I PG DFLY KL T DTYG LTEESFLKL AE LENMNC D LERYRAEVSLAKLKA K gnq RE 489
Cdd:pfam01411 370 ------------------ AKL K KGKK T L PG EDAF KL Y DTYG FPVDLTKEI AE ERGLKV D MPGFEYAMVEQRERS K --- QA 428
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 490 TAGGSL cdlateqria EAQAMLT K R L TP T DNSHK Y TYSFD kesdsyqippl KTRV L GMLLNDAE V S rt QGSRI Q QPF tdl 569
Cdd:pfam01411 429 VKEKGE ---------- KLDVSAL K E L PA T TEFLG Y DDLES ----------- EAKI L ALPKDGEF V A -- EVLAG Q EGG --- 482
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25012817 570 is IVTAGSN FY Y ESGGQ QS D G G K I LVSNHQQ pdhphsl D V IG V KHLNDC VVH IC KL S S PT dafq L AI GD E V ELQV D 645
Cdd:pfam01411 483 -- VILDRTP FY A ESGGQ IG D T G Y I IGDGGEF ------- R V TD V QKYGGV VVH KG KL E S GK ---- L KV GD K V IAVI D 545
alaS
TIGR00344 alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ...
16-822
6.80e-157
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain]
Cd Length: 845
Bit Score: 484.96
E-value: 6.80e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 16 EIR K TFLD H F T v NH GH KFVR S S P V VP FC DPT VAFV NAGM N QFK SV F L G TAAA P HK R VV N S Q K C V R V ggkh NDL SV VG TDG 95
Cdd:TIGR00344 1 EIR Q TFLD F F K - EK GH QVIP S A P L VP RN DPT LLLT NAGM A QFK PI F T G IVKP P SN R LT N A Q P C I R L ---- NDL EN VG RTA 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 96 Y HHT F FEMLGN W SFGDYFK R EA C A M A L ELL RGPYNI D PG RLYVT YFAG D K vlgipadl E CFE IW RSL G F PA S RI LPFGCA 175
Cdd:TIGR00344 76 R HHT L FEMLGN F SFGDYFK E EA I A F A W ELL TEVLGL D KE RLYVT VYED D E -------- E AYK IW EKI G I PA D RI IKCDAK 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 176 DNFW E MG a T GPCGPCTEI HI D H - RPDL G SVEQRA klvnagr SDLT E L WNLVF I Q Y NR HA DG SISQ LP AHHV DTGMG F ER L 254
Cdd:TIGR00344 148 DNFW D MG - D GPCGPCTEI YY D F v GGKP G EPLEEN ------- DRYL E V WNLVF M Q F NR DP DG NYTP LP KKNI DTGMG L ER F 219
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 255 T AVLQ NKSS NYDTD L F T P IFDG I QQAAKTPVY S GSFPDGGNAA V L D - T S Y R IL ADH A R MVTAC LADG ML P DQNQK --- LR 330
Cdd:TIGR00344 220 V AVLQ GVPT NYDTD I F L P LIEK I EEITGVKYD S NNAGIMDEKR V E D l R S L R VI ADH T R AIAFM LADG VV P SNEGR gyv LR 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 331 R VL R K AL NISEHVFAHDKL L TQ LVP IVV E T LG EA YPE MAA KQ QA V IDLICH E Q E VYKNLR E SSSKA F AEV L M efpnlddi 410
Cdd:TIGR00344 300 R LI R R AL RHGKKLGLKEAF L YK LVP TLI E V LG DY YPE LKE KQ EF V EQILEL E E E RFAKTL E RGLRL F EKL L K -------- 371
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 411 dlmecpgfvpayrelqmqrc K FSNNTIP G DFLY KL T DTYG LTE E SFLKL AE LENMNC D LERYR A EVS laklkakg N QRE T 490
Cdd:TIGR00344 372 -------------------- K TGKKELD G EDAF KL Y DTYG FPV E LTKEI AE ERGLTV D MPGFE A LMA -------- E QRE R 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 491 aggslcdl ATEQRIAEA Q AMLTKRLT P TDNSHK Y T ysf D K E SDS yqipplkt R V L G MLLNDAE V SRTQGSRIQQ pftdli 570
Cdd:TIGR00344 424 -------- SKQNSQFQE Q EIALVNVY P ATEFLG Y D --- D L E FEA -------- K V I G LFDDGYL V EQALAGQSVY ------ 478
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 571 s IVTAGSN FY Y ESGGQ QS D G G K i L VS N HQ qpdhph SLD V IG V KHL N DC V V H ICKLSSPT dafq L AI GD E V ELQV D AQQ R Q 650
Cdd:TIGR00344 479 - VILDQTP FY A ESGGQ IG D T G Y - L IA N DG ------ KFR V VD V QKP N GV V F H FGEVEGGS ---- L KV GD K V IAVI D EKR R F 546
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 651 LNTCH H T ATHLL N AA IRSLFKKVTY Q VS S S VS SDQCKLELGLL g KRIQKTDVQL IEDL I N RV I CSAA P VE V QLLSAA E VL 730
Cdd:TIGR00344 547 RIMRN H S ATHLL H AA LQKVLGNHVW Q AG S L VS FKKLRFDFSHF - RALTREELEE IEDL A N EQ I LANI P IK V IFMDLD E AK 625
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 731 EQNDITMVPGEVY P EQGL R L V N V ES pelql S S K ELC C GTH AT NT S E LSC F C IV NLKQTNRARFAFT AV A G Q AA ENV L K - T 809
Cdd:TIGR00344 626 RKGAFALFGEKYV P GEKV R V V S V GD ----- F S V ELC G GTH VR NT G E IGL F K IV KESGIAAGVRRIE AV T G E AA IEY L N e Q 700
810
....*....|...
gi 25012817 810 AAL L RHRV D L L EK 822
Cdd:TIGR00344 701 EDK L KELA D I L KV 713
AlaRS_core
cd00673 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ...
14-261
7.32e-113
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain]
Cd Length: 232
Bit Score: 347.81
E-value: 7.32e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 14 A R EIR K TFL DH F t VNH GH KF V R SSPVVP FC DPT VA F V NAGMNQFK SV FLG TAAA P HK R V VNSQKC V R V G GKH N dlsv VG T 93
Cdd:cd00673 1 A S EIR E TFL SF F - EKK GH TR V P SSPVVP RD DPT LL F T NAGMNQFK PI FLG EVPP P AN R L VNSQKC I R A G DID N ---- VG K 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 94 D G Y HHTFFEMLGN W SFGDYFK R EA C A M A L ELL RGPYNIDPG RLYV TY F A GD kvlgipa D L E CFEI W RSL G F P AS RI LPF G 173
Cdd:cd00673 76 T G R HHTFFEMLGN F SFGDYFK E EA I A F A W ELL TEVLGLPKD RLYV SV F E GD ------- D E E EAIW W WKI G L P GI RI ERI G 148
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 174 CA DNFWEMG AT GPCGPC T EI HI D HRPDLGS veqr A K L V N AGRSDLT E L WNLVF I QYNR H ADG SISQ LP AHH VDTGMG F ER 253
Cdd:cd00673 149 FK DNFWEMG GN GPCGPC S EI FY D RGEERDA ---- A S L P N EDDDRYL E I WNLVF M QYNR D ADG TYRP LP KKI VDTGMG L ER 224
....*...
gi 25012817 254 L TA VLQ NK 261
Cdd:cd00673 225 L VW VLQ GV 232
tRNA_SAD
smart00863 Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ...
748-784
2.13e-04
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain]
Cd Length: 43
Bit Score: 39.67
E-value: 2.13e-04
10 20 30
....*....|....*....|....*....|....*..
gi 25012817 748 L R L V NVES pelql S S K ELC C GTH AT NT S E LSC F C I VN 784
Cdd:smart00863 1 V R V V SIGD ----- F S V ELC G GTH VP NT G E IGA F K I LS 32
Name
Accession
Description
Interval
E-value
PLN02900
PLN02900 alanyl-tRNA synthetase
13-1010
0e+00
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain]
Cd Length: 936
Bit Score: 656.70
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 13 TARE IR K TFL DH F t VNH GH K F VR SSP V VP FC DPT VA F V NAGMNQFK SV FLGTA A ----- APHK R VV N S QKC V R V GGKHND 87
Cdd:PLN02900 12 PGDR IR R TFL SF F - ESK GH T F LP SSP L VP VD DPT LL F T NAGMNQFK PI FLGTA D pntpl RKLP R AT N T QKC I R A GGKHND 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 88 L SV VG T D G YHHTFFEMLGNWSFGDYFK R EA CAM A L ELL RGP Y NIDPG RLY V TYF A GD KVL gi PA D L E CFE IW RSL g F P AS 167
Cdd:PLN02900 91 L DD VG K D T YHHTFFEMLGNWSFGDYFK K EA IGW A W ELL TKV Y GLPAD RLY A TYF G GD EKQ -- AP D D E ARA IW LDY - L P EE 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 168 R I LPFGC A DNFWEMG A TGPCGPC T EIH I D HRPDLGS veqr A K LVN AGRSDLT E L WNLVFIQ Y NR H ADGS ISQ LPA H HVDT 247
Cdd:PLN02900 168 R V LPFGC K DNFWEMG D TGPCGPC S EIH Y D RIGERDA ---- A D LVN NDDPRFI E I WNLVFIQ F NR E ADGS LKP LPA K HVDT 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 248 GMG F ERL TAV LQNK S SNYDTDLF T PIFD G IQ Q A AKTPV Y S G SFPDGGNAA V l D TS YR IL ADH A R MVTACL ADG ML P D --- 324
Cdd:PLN02900 244 GMG L ERL ASI LQNK P SNYDTDLF M PIFD A IQ E A TGARP Y A G KVGAEDDDR V - D MA YR VV ADH I R TLSFAI ADG VV P S neg 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 325 QNQK LRR V LR K A ------- L NIS E HV F A hdkllt Q LV PI VVE TL G EAY PE MAAKQQAVIDL I CH E QEVYKNLR E SSSKA F 397
Cdd:PLN02900 323 RGYV LRR L LR R A vrygrll L GAE E GF F P ------ A LV EV VVE LS G DVF PE VKKNEKRITEI I AE E ELSFGKTL E KGIEK F 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 398 AEV L MEFPNLDD idlmecpgfvpayrelqmqrckfsn NTIP G DFLYK L T DTYG ---- LTE E sflk L AE LENMNC D L E RYR 473
Cdd:PLN02900 397 KKA L AAAKANGG ------------------------- PVLS G KDAFL L Y DTYG fpvd LTE L ---- M AE ERGVTV D M E GFE 447
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 474 A EVSL A KLKAK g NQRET AGG SLCD LA teqri AEA QAM L T K R - LTP TD NSH KY TY sf DKESDS yqipplkt R V LGM L LNDA 552
Cdd:PLN02900 448 A AMEE A RERSR - AAHLK AGG GAIE LA ----- AEA TSW L Q K Q g VAA TD DFL KY DW -- LSDHEA -------- V V KAI L TGGG 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 553 E V SRTQGS riqqpft D LIS IV TAGSN FY Y ESGGQ QS D G G KILV S NHQ qpdhph SLD V IG V KHLNDC V V HI CKLSSPT daf 632
Cdd:PLN02900 512 F V ESVSEG ------- D EVG IV LDKTS FY A ESGGQ IG D T G VLEG S GGA ------ VVE V SD V QKAGGF V L HI GTVTEGS --- 575
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 633 q LAI GD E V ELQ VD AQQ R QLNTCH HTATHLLN A A IRSLFKKVTY Q VS S S V SSDQCKLELG l L GK RIQKTDVQLI E D L I N RV 712
Cdd:PLN02900 576 - VSV GD A V TCK VD YDR R RRIAPN HTATHLLN S A LKEVLGDHVD Q KG S L V AFEKLRFDFS - H GK PMTPEELREV E S L V N EW 653
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 713 I CS A A PVE VQLLSA A EVLEQ N DITM V P GE V YP EQ g L R L V N V E spel QLS S K ELC C GTH AT NT S E LSC F CIVN ---- L K QT 788
Cdd:PLN02900 654 I GD A L PVE AKEMPL A DAKRI N GLRA V F GE K YP DP - V R V V S V G ---- GVY S M ELC G GTH VS NT A E AEA F KLLS eegi A K GI 728
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 789 N R arfa F TAV A G Q AA ENVLKT A AL L RHRV D llekqf QTD K LTNAT - E AELQTIRHNMLHTD I kl P Y A F K MDTLE R ITEML 867
Cdd:PLN02900 729 R R ---- I TAV T G G AA VEAINA A DS L EREL D ------ SAL K VEGSD l E KKVASLKSRVDAAV I -- P A A K K EEIRA R VSALQ 796
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 868 K RIKDSSRTTLKEFVD -- V EMR T L L QE K P L DTHP filhyits S A LV EEIP ------- L QR A T ---- KLCP D RPIL V I S VC 934
Cdd:PLN02900 797 K ELRAAQKEAAALRAK la V AKA T E L AS K A L SAGK -------- S V LV ARLD vgvdaaa L KE A A ekvi AKLG D PAAV V L S SD 868
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25012817 935 DSVV K ARCC -- VP EKCITEKFN A SA WL QSF A DT f N G QIAAP K GQNP Q A vcnm K GR RV snlfe E Q L EQ A MS KA H A Y A KL 1010
Cdd:PLN02900 869 EEKG K VSLV aa VP PGVVKKGLK A GK WL GAI A KL - C G GGGGG K PGFA Q G ---- Q GR DA ----- E K L DA A LE KA R A F A VA 936
AlaS
COG0013 Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ...
12-783
0e+00
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain]
Cd Length: 880
Bit Score: 618.22
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 12 L T AR EIR KT FLD H F t VNH GH KF V R SS PV VP FC DPT VA F V NAGM N QFK SV FLG TAAA P HK R VVN SQKCVR V GGKHNDL SV V 91
Cdd:COG0013 2 M T SA EIR QK FLD F F - ESK GH TI V P SS SL VP KN DPT LL F T NAGM V QFK PY FLG QEKP P YP R ATT SQKCVR T GGKHNDL EN V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 92 G TDGY HHTFFEMLGN W SFGDYFK R EA C A M A L ELL RGPYNIDPG RL Y VT YFAG D K vlgipadl E CFE IW RSL - G F P AS RI L 170
Cdd:COG0013 81 G YTAR HHTFFEMLGN F SFGDYFK E EA I A W A W ELL TEVLGLPKE RL W VT VYED D D -------- E AYD IW KKE i G V P EE RI I 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 171 PF G CA DNFWEMG A TGPCGPC T EI HI D HR P DL G SVEQRAKLVNAG R sd LT E L WNLVF I Q Y NR HA DG SISQ LP AHHV DTGMG 250
Cdd:COG0013 153 RL G KK DNFWEMG D TGPCGPC S EI FY D RG P EY G GGPPGSPGEDGD R -- YI E I WNLVF M Q F NR DE DG TLTP LP KKNI DTGMG 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 251 F ER LT AVLQ NKS SNY D TDLF T P IFDGIQQAAKTP v Y SGSFP D ggnaavl D T S Y R IL ADH A R M V TACL ADG M LP D q N QK -- 328
Cdd:COG0013 231 L ER IA AVLQ GVH SNY E TDLF R P LIEAAAELTGVK - Y GADEE D ------- D V S L R VI ADH I R A V AFLI ADG V LP S - N EG rg 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 329 -- LRR V LR K A ------ L N I S E HVFA hdkllt Q LVP I VVE TL G E AYPE MAA KQ QAVIDLICH E Q E vyknlresssk A F AEV 400
Cdd:COG0013 302 yv LRR I LR R A vrhgrl L G I K E PFLY ------ K LVP V VVE EM G D AYPE LKE KQ ELIEKVLKA E E E ----------- R F LRT 364
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 401 L --- MEF pn LD DI dl ME cpgfvpayr E L Q mqrc KFSNNTIP G DFLY KL T DTYG ---- LTEE sflk L A ELENMNC D L E RYR 473
Cdd:COG0013 365 L erg LKL -- LD EA -- IA --------- K L K ---- AAGGKVLS G EDAF KL Y DTYG fpld LTEE ---- I A RERGLTV D E E GFE 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 474 A EVSLAKLK A KGNQRETAGGSLCDLAT E qriaeaqam L TKRLT PT D nshkytys F --- D KESD syqippl KTR VL GMLLN 550
Cdd:COG0013 424 A AMEEQRER A RAAAKFSGDAAVDGVWR E --------- L LEEGG PT E -------- F vgy D TLEA ------- EAK VL ALVKD 479
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 551 DAE V SR - TQ G SRIQ qpftdlis I V TAGSN FY Y ESGGQ QS D G G K I LVSNHQ qpdhphs LD V IGV - K HLNDCV VHI C K LSSP 628
Cdd:COG0013 480 GEL V DS a KA G EEVE -------- V V LDRTP FY A ESGGQ VG D T G T I EGDGGV ------- FE V TDT q K PPGGLI VHI G K VEEG 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 629 T dafq L AI GD E V EL QVDA QQ R QLNTCH H T ATHLL N AA I R ----------- SL ------------ F KKV T yqvsssvssdq 685
Cdd:COG0013 545 E ---- L KV GD T V TA QVDA ER R RAIARN H S ATHLL H AA L R evlgehvtqag SL vapdrlrfdfsh F EAL T ----------- 609
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 686 cklelgllgkriq KTDVQL IEDL I N RV I CSAA PVE VQLLSAA E VLEQNDITMV p GE V Y PEQ g L R L V NVESP elqls S K EL 765
Cdd:COG0013 610 ------------- PEELAE IEDL V N EK I RENL PVE TREMPLD E AKALGAMALF - GE K Y GDE - V R V V SIGDF ----- S R EL 669
810
....*....|....*...
gi 25012817 766 C C GTH ATN T SELSC F C IV 783
Cdd:COG0013 670 C G GTH VSR T GDIGL F K IV 687
tRNA-synt_2c
pfam01411 tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ...
16-645
3.80e-161
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain]
Cd Length: 548
Bit Score: 485.63
E-value: 3.80e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 16 EIR K TFLD H F t VNH GH KF V R SSPVVP FC DPT VA F V NAGMNQFK SV FLG TA A - A P HK R VV NSQKC V R V G gkhn DL SV VG TD 94
Cdd:pfam01411 1 EIR Q TFLD F F - EKK GH TR V P SSPVVP RN DPT LL F T NAGMNQFK PI FLG GV A k P P YN R AT NSQKC I R A G ---- DL EN VG RT 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 95 G Y HHTFFEMLGN W SFGDYFK R EA CAM A L ELL RGPYNID P G RLYVT Y F AG D K vlgipadl E CFE IW RSL - G F P AS RIL P FG 173
Cdd:pfam01411 76 G R HHTFFEMLGN F SFGDYFK E EA IEY A W ELL TKELGLP P E RLYVT V F EW D D -------- E AGP IW EKI v G G P EE RIL R FG 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 174 CA DNFWEMG A TGPCGPC T EI HI D HRPDL G s VEQRAKLVN A GRSDLT E L WNLVF I Q Y NR HA DG SISQ LP AHHV DTGMG F ER 253
Cdd:pfam01411 148 DK DNFWEMG D TGPCGPC S EI DY D RGEEI G - GWDSGGTPT A DDDRFL E I WNLVF M Q F NR EN DG TLKP LP KKSI DTGMG L ER 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 254 L T AVLQ NKS SNYDTD L F T P IFDG I QQAAKTPV Y S gsfpdggn AAVL D TS YR IL ADH A R MV T AC LADG ML P D q N QK ---- L 329
Cdd:pfam01411 227 L V AVLQ DVR SNYDTD V F I P VIEL I EEISGARY Y T -------- VDET D EA YR VI ADH T R AL T FA LADG VV P S - N EG rgyv L 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 330 RR V LR K A LNISEHVFAHDKL L TQ LVP I VVE T LG E AYPE MAAKQQAVIDLICH E Q E VYKNLR E SSSKAFAEVL mefpnldd 409
Cdd:pfam01411 298 RR I LR R A VRHAKKLGLKEPF L YD LVP T VVE V LG D AYPE LKEDEDFIQEILEL E E E RFAKTL E RGLRLLERLI -------- 369
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 410 idlmecpgfvpayrelqm QRC K FSNN T I PG DFLY KL T DTYG LTEESFLKL AE LENMNC D LERYRAEVSLAKLKA K gnq RE 489
Cdd:pfam01411 370 ------------------ AKL K KGKK T L PG EDAF KL Y DTYG FPVDLTKEI AE ERGLKV D MPGFEYAMVEQRERS K --- QA 428
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 490 TAGGSL cdlateqria EAQAMLT K R L TP T DNSHK Y TYSFD kesdsyqippl KTRV L GMLLNDAE V S rt QGSRI Q QPF tdl 569
Cdd:pfam01411 429 VKEKGE ---------- KLDVSAL K E L PA T TEFLG Y DDLES ----------- EAKI L ALPKDGEF V A -- EVLAG Q EGG --- 482
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25012817 570 is IVTAGSN FY Y ESGGQ QS D G G K I LVSNHQQ pdhphsl D V IG V KHLNDC VVH IC KL S S PT dafq L AI GD E V ELQV D 645
Cdd:pfam01411 483 -- VILDRTP FY A ESGGQ IG D T G Y I IGDGGEF ------- R V TD V QKYGGV VVH KG KL E S GK ---- L KV GD K V IAVI D 545
alaS
TIGR00344 alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ...
16-822
6.80e-157
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain]
Cd Length: 845
Bit Score: 484.96
E-value: 6.80e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 16 EIR K TFLD H F T v NH GH KFVR S S P V VP FC DPT VAFV NAGM N QFK SV F L G TAAA P HK R VV N S Q K C V R V ggkh NDL SV VG TDG 95
Cdd:TIGR00344 1 EIR Q TFLD F F K - EK GH QVIP S A P L VP RN DPT LLLT NAGM A QFK PI F T G IVKP P SN R LT N A Q P C I R L ---- NDL EN VG RTA 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 96 Y HHT F FEMLGN W SFGDYFK R EA C A M A L ELL RGPYNI D PG RLYVT YFAG D K vlgipadl E CFE IW RSL G F PA S RI LPFGCA 175
Cdd:TIGR00344 76 R HHT L FEMLGN F SFGDYFK E EA I A F A W ELL TEVLGL D KE RLYVT VYED D E -------- E AYK IW EKI G I PA D RI IKCDAK 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 176 DNFW E MG a T GPCGPCTEI HI D H - RPDL G SVEQRA klvnagr SDLT E L WNLVF I Q Y NR HA DG SISQ LP AHHV DTGMG F ER L 254
Cdd:TIGR00344 148 DNFW D MG - D GPCGPCTEI YY D F v GGKP G EPLEEN ------- DRYL E V WNLVF M Q F NR DP DG NYTP LP KKNI DTGMG L ER F 219
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 255 T AVLQ NKSS NYDTD L F T P IFDG I QQAAKTPVY S GSFPDGGNAA V L D - T S Y R IL ADH A R MVTAC LADG ML P DQNQK --- LR 330
Cdd:TIGR00344 220 V AVLQ GVPT NYDTD I F L P LIEK I EEITGVKYD S NNAGIMDEKR V E D l R S L R VI ADH T R AIAFM LADG VV P SNEGR gyv LR 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 331 R VL R K AL NISEHVFAHDKL L TQ LVP IVV E T LG EA YPE MAA KQ QA V IDLICH E Q E VYKNLR E SSSKA F AEV L M efpnlddi 410
Cdd:TIGR00344 300 R LI R R AL RHGKKLGLKEAF L YK LVP TLI E V LG DY YPE LKE KQ EF V EQILEL E E E RFAKTL E RGLRL F EKL L K -------- 371
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 411 dlmecpgfvpayrelqmqrc K FSNNTIP G DFLY KL T DTYG LTE E SFLKL AE LENMNC D LERYR A EVS laklkakg N QRE T 490
Cdd:TIGR00344 372 -------------------- K TGKKELD G EDAF KL Y DTYG FPV E LTKEI AE ERGLTV D MPGFE A LMA -------- E QRE R 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 491 aggslcdl ATEQRIAEA Q AMLTKRLT P TDNSHK Y T ysf D K E SDS yqipplkt R V L G MLLNDAE V SRTQGSRIQQ pftdli 570
Cdd:TIGR00344 424 -------- SKQNSQFQE Q EIALVNVY P ATEFLG Y D --- D L E FEA -------- K V I G LFDDGYL V EQALAGQSVY ------ 478
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 571 s IVTAGSN FY Y ESGGQ QS D G G K i L VS N HQ qpdhph SLD V IG V KHL N DC V V H ICKLSSPT dafq L AI GD E V ELQV D AQQ R Q 650
Cdd:TIGR00344 479 - VILDQTP FY A ESGGQ IG D T G Y - L IA N DG ------ KFR V VD V QKP N GV V F H FGEVEGGS ---- L KV GD K V IAVI D EKR R F 546
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 651 LNTCH H T ATHLL N AA IRSLFKKVTY Q VS S S VS SDQCKLELGLL g KRIQKTDVQL IEDL I N RV I CSAA P VE V QLLSAA E VL 730
Cdd:TIGR00344 547 RIMRN H S ATHLL H AA LQKVLGNHVW Q AG S L VS FKKLRFDFSHF - RALTREELEE IEDL A N EQ I LANI P IK V IFMDLD E AK 625
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 731 EQNDITMVPGEVY P EQGL R L V N V ES pelql S S K ELC C GTH AT NT S E LSC F C IV NLKQTNRARFAFT AV A G Q AA ENV L K - T 809
Cdd:TIGR00344 626 RKGAFALFGEKYV P GEKV R V V S V GD ----- F S V ELC G GTH VR NT G E IGL F K IV KESGIAAGVRRIE AV T G E AA IEY L N e Q 700
810
....*....|...
gi 25012817 810 AAL L RHRV D L L EK 822
Cdd:TIGR00344 701 EDK L KELA D I L KV 713
AlaRS_core
cd00673 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ...
14-261
7.32e-113
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain]
Cd Length: 232
Bit Score: 347.81
E-value: 7.32e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 14 A R EIR K TFL DH F t VNH GH KF V R SSPVVP FC DPT VA F V NAGMNQFK SV FLG TAAA P HK R V VNSQKC V R V G GKH N dlsv VG T 93
Cdd:cd00673 1 A S EIR E TFL SF F - EKK GH TR V P SSPVVP RD DPT LL F T NAGMNQFK PI FLG EVPP P AN R L VNSQKC I R A G DID N ---- VG K 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 94 D G Y HHTFFEMLGN W SFGDYFK R EA C A M A L ELL RGPYNIDPG RLYV TY F A GD kvlgipa D L E CFEI W RSL G F P AS RI LPF G 173
Cdd:cd00673 76 T G R HHTFFEMLGN F SFGDYFK E EA I A F A W ELL TEVLGLPKD RLYV SV F E GD ------- D E E EAIW W WKI G L P GI RI ERI G 148
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 174 CA DNFWEMG AT GPCGPC T EI HI D HRPDLGS veqr A K L V N AGRSDLT E L WNLVF I QYNR H ADG SISQ LP AHH VDTGMG F ER 253
Cdd:cd00673 149 FK DNFWEMG GN GPCGPC S EI FY D RGEERDA ---- A S L P N EDDDRYL E I WNLVF M QYNR D ADG TYRP LP KKI VDTGMG L ER 224
....*...
gi 25012817 254 L TA VLQ NK 261
Cdd:cd00673 225 L VW VLQ GV 232
PRK01584
PRK01584 alanyl-tRNA synthetase; Provisional
12-493
4.06e-88
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain]
Cd Length: 594
Bit Score: 294.76
E-value: 4.06e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 12 L T AR E I RK TFL D H F t VNH GH KFVRSSPVV P FC DPTV A F VN AGM NQFKSVF LG TAAAPHK R V V NS QKC V R V G gkhn D LSV V 91
Cdd:PRK01584 1 M T LD E L RK KYI D F F - KSK GH VEIAGKSLI P EN DPTV L F TT AGM HPLVPYL LG EPHPSGT R L V DV QKC L R T G ---- D IDE V 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 92 G t D GY H H TFFEMLGNWS F G D YFK R E ACAMAL E L L RG P Y -- NI DPGR LYVT Y F A GD KV lg IP A D L E CFEI W R SLG F P AS RI 169
Cdd:PRK01584 76 G - D LS H L TFFEMLGNWS L G A YFK E E SIKYSF E F L TS P D yl NI PKDK LYVT V F E GD EE -- IP R D E E TASV W E SLG I P KD RI 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 170 LPFGCAD N F W - EM G A TGPCGP C TEI HI D HRPDLG SV EQ R AK l VNA G R sd LT E L WN L VF I QYN RHA DG SISQ L PAHH VDTG 248
Cdd:PRK01584 153 FYLSREH N W W g PV G E TGPCGP D TEI FV D TGKPKC SV NC R PT - CSC G K -- YF E I WN N VF M QYN KDE DG NYEE L KRKC VDTG 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 249 MG F ER LT A V LQ N KSS N YDT DL FTPI FDG I QQAAKT p V Y sgsfpdg G NAAVL D T S Y RI L ADH A R MVTAC L A D -- GM LP D -- 324
Cdd:PRK01584 230 MG I ER TI A F LQ G KSS V YDT EA FTPI IKR I EKISGK - I Y ------- G QNEED D R S I RI I ADH I R AACFI L G D pf VV LP S nv 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 325 - Q NQK LRR VL R KALNISEHVFAHDKL L TQ LV PI V V E TL G EA YPE MAA K Q qavi D L I CH E QEV - YKNLRESSS K AFA E VLM 402
Cdd:PRK01584 302 g Q GYV LRR LI R RSIRHAKKLGIESHF L AD LV DS V E E IY G SF YPE LTE K K ---- D F I KE E LNK e EEKFFKTLR K GEQ E FIK 377
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 403 EF PNL ddidlmecpgfvpayrelqmqrck F S NNT IPGD FLY KL T DTYG LTE E SFLK LA ELENMNC D L E RY ra EVSLA K -- 480
Cdd:PRK01584 378 LI PNL ------------------------ G S SKI IPGD IAF KL Y DTYG FPY E ITEE LA SEYGFTV D R E GF -- DEHFK K hq 431
490
....*....|....
gi 25012817 481 - LKA KG NQRETA GG 493
Cdd:PRK01584 432 k VSK KG ADKVFK GG 445
A-tRNA_syn_arch
TIGR03683 alanyl-tRNA synthetase; This family of alanyl-tRNA synthetases is limited to the archaea, and ...
10-811
1.93e-45
alanyl-tRNA synthetase; This family of alanyl-tRNA synthetases is limited to the archaea, and is a subset of those sequences identified by the model pfam07973 covering the second additional domain (SAD) of alanyl and threonyl tRNA synthetases .
Pssm-ID: 274722 [Multi-domain]
Cd Length: 902
Bit Score: 177.49
E-value: 1.93e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 10 RVL T AR E I R KT FL DH F T v N HGH KFVRSS PVV PFCDPT V AFVN A GMNQ F KS - V FL G TAAA P HKRV V N SQ K C V R V ggkh ND L 88
Cdd:TIGR03683 54 KKY T LD E M R EA FL SF F E - K HGH TRIKRY PVV ARWRDD V YLTI A SIAD F QP w V TS G LVPP P ANPL V I SQ P C I R L ---- ND I 128
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 89 SV VG TD G Y H H T F FEM LGNWS F GD ----- Y F K R E ACAMAL E L L rgpynidpgrlyvtyfagd KV LGI PADLECF - E IW rsl 162
Cdd:TIGR03683 129 DN VG RT G R H L T C FEM MAHHA F NY pdkei Y W K D E TVEYCF E F L ------------------- EE LGI DPEEITY k E SP --- 186
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 163 gfpasrilpfgcadnf WE M G at G PC GPC T E I hidhrpdlgsveqrak L V NA grsdl T EL WN LVF I QY NRHAD G S I ----- 237
Cdd:TIGR03683 187 ---------------- WE G G -- G NA GPC F E V ---------------- I V GG ----- L EL AT LVF M QY EEDKE G E I eikgg 227
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 238 -- S QL P AHH VDTG M G F ER LTAVL Q NKSSN YD T d L F TP I F D GIQQA A KTPV ----------- YS G SF - PDG ---------- 293
Cdd:TIGR03683 228 ry S EM P LKI VDTG Y G L ER FVWAS Q GTPTA YD A - I F PE I V D KLKEN A GVEL ideeilaenar LA G MM d IED eedlrelrkk 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 294 - GNAAVL D TSY --------- RI -- L ADH A R MVTAC L A DG ML P d Q N Q K -------- L RR V LR -- KA L NISEH vfahdkl L T 351
Cdd:TIGR03683 307 v ADKIGI D VEE lekiiapve RI ya I ADH T R CLAFM L G DG IV P - S N V K egylarlv I RR T LR lm RE L GLDIP ------- L S 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 352 Q LV PIVV E T L GEA YPE MAAKQQAVI D LICH E Q E V Y knl RE SSSKAFAE V lmefpnlddidlmecpgfvpa Y R E L Q mqrck 431
Cdd:TIGR03683 379 D LV EMQL E E L KKI YPE LKENKDYIL D ILDL E E E K Y --- RE TLERGRRI V --------------------- E R L L K ----- 429
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 432 f SNNT IP G D F L YK L T D TY G LTE E SFLKL A ELENMNCDL - ERYRAE V sl A KLKA K GNQR E ta GGSLCDLATEQRIA E aqam 510
Cdd:TIGR03683 430 - TKKE IP L D D L IE L Y D SH G IPP E IVKEI A AELGAEVEI p DNFYSI V -- A ERHE K EEKE E -- ESPKDYEERAKDLP E ---- 500
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 511 l T K RL T ptdnshk Y TYSFDK E sdsyqipp LKTR VLG ml LN D AE V SRT Q gsriqqpftdlisiv TA gsn FY Y E S GGQ QS D G 590
Cdd:TIGR03683 501 - T R RL F ------- Y EDPTMR E -------- FEAK VLG -- VF D NY V VLD Q --------------- TA --- FY P E G GGQ PA D T 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 591 G KILVSNHQ qpdhphs LD V IG V KHLNDCV VH ICKLSSPTD afqlai GDEV ELQV D AQQ R QLNTC HHTATH L L N AA I R SLF 670
Cdd:TIGR03683 545 G YLITNGGE ------- YR V VD V QKVGGVI VH KVDGEGIKE ------ GDEV KGEI D WER R LRLMR HHTATH V L L AA A R RVL 611
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 671 KKVTY Q VSSSVSS D QCK L ELGLL g KRI QKTDVQL IE D L I NR VICSAA PV E V QLLSAA E VLEQNDITMVP G E V Y P EQGL R L 750
Cdd:TIGR03683 612 GRHVW Q AGAQKDT D KAR L DITHY - KRI SEEEIKE IE R L A NR IVMENR PV S V KWMDRN E AEQKYGFRLYQ G G V P P GREI R V 690
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 751 V NV E SPEL Q lsske L C C GTH AT NT S E LSCFC I VNLK -- Q TNRA R FA F ta V AG Q AA ------- E NV L KTAA 811
Cdd:TIGR03683 691 V EI E DWDV Q ----- A C G GTH CR NT G E IGPIK I LKTE ri Q DGVE R IE F -- A AG E AA leyiqel E DL L RESS 753
AlaX
COG2872 Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ...
572-776
7.60e-23
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain]
Cd Length: 238
Bit Score: 98.34
E-value: 7.60e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 572 I V TAGSN FY YES GGQ QS D G G KILVSNH qqpdhph SLD V IG V KHLNDCV VH I cklss PTD A FQLAI GDEV ELQV D AQQ R QL 651
Cdd:COG2872 28 V V LDRTA FY PTG GGQ PG D T G TLVWDGK ------- EIR V VD V RKEDGEI VH V ----- LEG A PLPEV GDEV TGEI D WER R YR 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 652 NTCH HTA T HLL N A AIRSLFK - K VT ---- Y qvsssvs S D QCKLELG L lg KRIQKT D VQL IE DLI N RV I CSAA PV EVQLLSA 726
Cdd:COG2872 96 HMRL HTA L HLL S A VVYREYG a P VT ggqi G ------- E D RARIDFD L -- PEFDEE D LEE IE AEA N EL I AADL PV RIYWITR 166
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 25012817 727 A E VLEQNDI -- TM v PGEVY P EQ G - L R L V NVESPE LQ lsske L C C GTH AT NT S E 776
Cdd:COG2872 167 E E LEAIPGL vr TM - SVLPP P GV G r V R I V EIGGVD LQ ----- P C G GTH VA NT G E 213
PLN02961
PLN02961 alanine-tRNA ligase
570-667
3.59e-05
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain]
Cd Length: 223
Bit Score: 46.23
E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25012817 570 I SI V TAGSN F YYES GGQ Q SD G G K I LV S NHQQ pdhph SLD V IG V KHLNDC V V H ICKLSSPTDAFQ -- LAI GDEV ELQ VD AQ 647
Cdd:PLN02961 3 I AL V LDRTI F HPQG GGQ P SD T G R I VI S GGDT ----- KFS V QD V RRKDGV V Y H YGVFEGSNPESA sp FEA GDEV TVT VD ES 77
90 100
....*....|....*....|
gi 25012817 648 Q R Q L NTCH H T A T HLL NAAIR 667
Cdd:PLN02961 78 R R K L HSRL H S A G HLL DVCMA 97
tRNA_SAD
smart00863 Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ...
748-784
2.13e-04
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain]
Cd Length: 43
Bit Score: 39.67
E-value: 2.13e-04
10 20 30
....*....|....*....|....*....|....*..
gi 25012817 748 L R L V NVES pelql S S K ELC C GTH AT NT S E LSC F C I VN 784
Cdd:smart00863 1 V R V V SIGD ----- F S V ELC G GTH VP NT G E IGA F K I LS 32
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
