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Conserved domains on  [gi|37724063|gb|AAN61067|]
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doublesex- and mab-3-related transcription factor 1 c2 [Danio rerio]

Protein Classification

DM and Dmrt1 domain-containing protein( domain architecture ID 11107805)

DM and Dmrt1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DM pfam00751
DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single ...
 18-64 1.14e-25

DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. The dsx DM domain has been shown to dimerize and bind palindromic DNA.


:

Pssm-ID: 459924  Cd Length: 47  Bit Score: 91.19  E-value: 1.14e-25
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 37724063    18 RMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQ 64
Cdd:pfam00751   1 RSPKCARCRNHGVRVPLKGHKRYCPYRDCSCPKCLLVAERQRVMAAQ 47
Dmrt1 super family cl13767
Double-sex mab3 related transcription factor 1; This domain family is found in eukaryotes, and ...
 76-103 2.41e-10

Double-sex mab3 related transcription factor 1; This domain family is found in eukaryotes, and is typically between 61 and 73 amino acids in length. The family is found in association with pfam00751. This family is a transcription factor involved in sex determination. The proteins in this family contain a zinc finger-like DNA-binding motif, DM domain.


The actual alignment was detected with superfamily member pfam12374:

Pssm-ID: 463555  Cd Length: 71  Bit Score: 52.83  E-value: 2.41e-10
                          10        20
                  ....*....|....*....|....*...
gi 37724063    76 EMGICSPINLSGSDTLVKNEAVGENVFT 103
Cdd:pfam12374   1 ELGISSPVPLPGAEVLVKNEAGADCLFS 28
 
Name Accession Description Interval E-value
DM pfam00751
DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single ...
 18-64 1.14e-25

DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. The dsx DM domain has been shown to dimerize and bind palindromic DNA.


Pssm-ID: 459924  Cd Length: 47  Bit Score: 91.19  E-value: 1.14e-25
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 37724063    18 RMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQ 64
Cdd:pfam00751   1 RSPKCARCRNHGVRVPLKGHKRYCPYRDCSCPKCLLVAERQRVMAAQ 47
DM smart00301
Doublesex DNA-binding motif;
18-71 1.13e-17

Doublesex DNA-binding motif;


Pssm-ID: 214606  Cd Length: 54  Bit Score: 71.24  E-value: 1.13e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 37724063     18 RMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQVALRRQQ 71
Cdd:smart00301   1 RIPYCQKCENHGVKVPLKGHKPECPFRDCECEKCTLVEKRRALMALQIKLKREQ 54
Dmrt1 pfam12374
Double-sex mab3 related transcription factor 1; This domain family is found in eukaryotes, and ...
 76-103 2.41e-10

Double-sex mab3 related transcription factor 1; This domain family is found in eukaryotes, and is typically between 61 and 73 amino acids in length. The family is found in association with pfam00751. This family is a transcription factor involved in sex determination. The proteins in this family contain a zinc finger-like DNA-binding motif, DM domain.


Pssm-ID: 463555  Cd Length: 71  Bit Score: 52.83  E-value: 2.41e-10
                          10        20
                  ....*....|....*....|....*...
gi 37724063    76 EMGICSPINLSGSDTLVKNEAVGENVFT 103
Cdd:pfam12374   1 ELGISSPVPLPGAEVLVKNEAGADCLFS 28
 
Name Accession Description Interval E-value
DM pfam00751
DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single ...
 18-64 1.14e-25

DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. The dsx DM domain has been shown to dimerize and bind palindromic DNA.


Pssm-ID: 459924  Cd Length: 47  Bit Score: 91.19  E-value: 1.14e-25
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 37724063    18 RMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQ 64
Cdd:pfam00751   1 RSPKCARCRNHGVRVPLKGHKRYCPYRDCSCPKCLLVAERQRVMAAQ 47
DM smart00301
Doublesex DNA-binding motif;
18-71 1.13e-17

Doublesex DNA-binding motif;


Pssm-ID: 214606  Cd Length: 54  Bit Score: 71.24  E-value: 1.13e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 37724063     18 RMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQVALRRQQ 71
Cdd:smart00301   1 RIPYCQKCENHGVKVPLKGHKPECPFRDCECEKCTLVEKRRALMALQIKLKREQ 54
Dmrt1 pfam12374
Double-sex mab3 related transcription factor 1; This domain family is found in eukaryotes, and ...
 76-103 2.41e-10

Double-sex mab3 related transcription factor 1; This domain family is found in eukaryotes, and is typically between 61 and 73 amino acids in length. The family is found in association with pfam00751. This family is a transcription factor involved in sex determination. The proteins in this family contain a zinc finger-like DNA-binding motif, DM domain.


Pssm-ID: 463555  Cd Length: 71  Bit Score: 52.83  E-value: 2.41e-10
                          10        20
                  ....*....|....*....|....*...
gi 37724063    76 EMGICSPINLSGSDTLVKNEAVGENVFT 103
Cdd:pfam12374   1 ELGISSPVPLPGAEVLVKNEAGADCLFS 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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