NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|28381307|gb|AAN13658|]
View 

3-hydroxyisobutyryl-CoA hydrolase, isoform B [Drosophila melanogaster]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
56-375 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 544.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    56 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRALVEA---GPTDESKSFFREEYSTN 130
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAvkLVVLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   131 ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGA 210
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   211 DVYYSGIATHYCESSKIPDLETALLNCP--DADDVPELLQKYH-SPPEKPFSLQPVLEQINKNFSADSVEGILENLQN-- 285
Cdd:pfam16113 162 DALAAGLATHYVPSARLPALEEALAALDwsDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAea 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   286 DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLAD 365
Cdd:pfam16113 242 DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPATLEE 321
                         330
                  ....*....|
gi 28381307   366 VTEEHVQWFF 375
Cdd:pfam16113 322 VTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
56-375 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 544.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    56 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRALVEA---GPTDESKSFFREEYSTN 130
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAvkLVVLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   131 ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGA 210
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   211 DVYYSGIATHYCESSKIPDLETALLNCP--DADDVPELLQKYH-SPPEKPFSLQPVLEQINKNFSADSVEGILENLQN-- 285
Cdd:pfam16113 162 DALAAGLATHYVPSARLPALEEALAALDwsDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAea 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   286 DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLAD 365
Cdd:pfam16113 242 DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPATLEE 321
                         330
                  ....*....|
gi 28381307   366 VTEEHVQWFF 375
Cdd:pfam16113 322 VTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
44-376 6.55e-155

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 440.03  E-value: 6.55e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   44 SSSVLATESSNK-GMIILNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGDKAFCAGGDVRALVEA---GPTD 117
Cdd:PRK05617   1 TEDEVLAEVEGGvGVITLNRPKALNALSLEMIRAIDAALDAWEDddAVAAVVIEGAGERGFCAGGDIRALYEAaraGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  118 ESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLG 197
Cdd:PRK05617  81 AADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  198 LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCP---DADDVPELLQKYHSPPEKPfSLQPVLEQINKNFSAD 274
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRwdsGADVVDAALAAFATPAPAS-ELAAQRAWIDECFAGD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  275 SVEGILENLQNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQ 354
Cdd:PRK05617 240 TVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKDR 319
                        330       340
                 ....*....|....*....|..
gi 28381307  355 KPQWQPTKLADVTEEHVQWFFR 376
Cdd:PRK05617 320 NPKWSPATLEDVTPEDVEAFFA 341
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
58-235 4.94e-51

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 169.28  E-value: 4.94e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGP-TDESKSFFREEYSTNALIG 134
Cdd:cd06558  12 ITLNRPEKRNALSLEMLDELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAALSDaGEEARAFIRELQELLRALL 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 135 NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVY 213
Cdd:cd06558  91 RLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELLLTGRRISAEEAL 170
                       170       180
                ....*....|....*....|..
gi 28381307 214 YSGIATHYCESSKIPDLETALL 235
Cdd:cd06558 171 ELGLVDEVVPDEELLAAALELA 192
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
58-349 3.72e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 153.40  E-value: 3.72e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 135
Cdd:COG1024  12 ITLNRPEKLNALSLEMLAELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAAAADPEEARAFARGLQRLFRALRR 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 136 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVYY 214
Cdd:COG1024  91 LPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELLLTGRRIDAEEALE 170
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 215 SGIATHYCESSkipdletallncpdaddvpELLQKyhsppekpfslqpvleqinknfsadsvegilenlqndgsewAKKT 294
Cdd:COG1024 171 LGLVNRVVPDD-------------------ELLAA-----------------------------------------ALAL 190
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*
gi 28381307 295 LETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALL 349
Cdd:COG1024 191 AARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
58-195 2.18e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.50  E-value: 2.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 135
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIgvVILTGAGDKAFCSGGDQKVRGDYGYIDDSGVHRLNVLDVQRQIRT 95
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   136 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 195
Cdd:TIGR01929  96 CPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQ 155
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
56-375 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 544.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    56 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRALVEA---GPTDESKSFFREEYSTN 130
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAvkLVVLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   131 ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGA 210
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   211 DVYYSGIATHYCESSKIPDLETALLNCP--DADDVPELLQKYH-SPPEKPFSLQPVLEQINKNFSADSVEGILENLQN-- 285
Cdd:pfam16113 162 DALAAGLATHYVPSARLPALEEALAALDwsDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAea 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   286 DGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLAD 365
Cdd:pfam16113 242 DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPATLEE 321
                         330
                  ....*....|
gi 28381307   366 VTEEHVQWFF 375
Cdd:pfam16113 322 VTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
44-376 6.55e-155

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 440.03  E-value: 6.55e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   44 SSSVLATESSNK-GMIILNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGDKAFCAGGDVRALVEA---GPTD 117
Cdd:PRK05617   1 TEDEVLAEVEGGvGVITLNRPKALNALSLEMIRAIDAALDAWEDddAVAAVVIEGAGERGFCAGGDIRALYEAaraGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  118 ESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLG 197
Cdd:PRK05617  81 AADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  198 LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCP---DADDVPELLQKYHSPPEKPfSLQPVLEQINKNFSAD 274
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRwdsGADVVDAALAAFATPAPAS-ELAAQRAWIDECFAGD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  275 SVEGILENLQNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQ 354
Cdd:PRK05617 240 TVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKDR 319
                        330       340
                 ....*....|....*....|..
gi 28381307  355 KPQWQPTKLADVTEEHVQWFFR 376
Cdd:PRK05617 320 NPKWSPATLEDVTPEDVEAFFA 341
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
47-386 2.63e-99

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 299.79  E-value: 2.63e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   47 VLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGdKAFCAGGDVRALVEAGPTDES-KSFF 123
Cdd:PLN02874  13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSveLIIIKGAG-RAFSAGGDLKMFYDGRESDDScLEVV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  124 REEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLT 203
Cdd:PLN02874  92 YRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGEYLALT 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  204 GYRLRGADVYYSGIATHYCESSKIPDLETAL--LNCPDADDVPELLQKYHSPPE-KPFSLQPVLEQINKNFSADSVEGIL 280
Cdd:PLN02874 172 GARLNGKEMVACGLATHFVPSEKLPELEKRLlnLNSGDESAVQEAIEEFSKDVQaDEDSILNKQSWINECFSKDTVEEII 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  281 ENLQ----NDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRL---AVRHLERSDFKEGVRALLIDKD 353
Cdd:PLN02874 252 KAFEseasKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLtmnILRSTVSDDVYEGIRALVIDKD 331
                        330       340       350
                 ....*....|....*....|....*....|...
gi 28381307  354 QKPQWQPTKLADVTEEHVQWFFRKLPDTEELKL 386
Cdd:PLN02874 332 NAPKWNPSTLDEVTDEKVDLVFQPFKAREELQL 364
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
59-386 1.58e-91

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 281.10  E-value: 1.58e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   59 ILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRAL---VEAGPTDESKSFFREEYSTNALI 133
Cdd:PLN02851  56 ILNRPSSLNALTIPMVARLKRLYESWEENPDIgfVLMKGSG-RAFCSGADVVSLyhlINEGNVEECKLFFENLYKFVYLQ 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  134 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVY 213
Cdd:PLN02851 135 GTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGYLGEYLALTGQKLNGVEMI 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  214 YSGIATHYCESSKIPDLETAL--LNCPDADDVPELLQKYHSP--PEKPFSLQPVlEQINKNFSADSVEGILENLQNDGS- 288
Cdd:PLN02851 215 ACGLATHYCLNARLPLIEERLgkLLTDDPAVIEDSLAQYGDLvyPDKSSVLHKI-ETIDKCFGHDTVEEIIEALENEAAs 293
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  289 ---EWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLER---SDFKEGVRALLIDKDQKPQWQPTK 362
Cdd:PLN02851 294 sydEWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLAREYRISLCGVSKwvsGDFCEGVRARLVDKDFAPKWDPPS 373
                        330       340
                 ....*....|....*....|....*
gi 28381307  363 LADVTEEHVQWFFRKLPDTE-ELKL 386
Cdd:PLN02851 374 LGEVSKDMVDCYFTPLDESEsELEL 398
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
43-383 4.63e-89

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 273.90  E-value: 4.63e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   43 SSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGdKAFCAGGDVRALV---EAGPTD 117
Cdd:PLN02988   7 SQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSvkLVILKGHG-RAFCAGGDVAAVVrdiEQGNWR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  118 ESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLG 197
Cdd:PLN02988  86 LGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFG 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  198 LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDV--PELLQKYHSPPE-KPFSLQPVLEQINKNFSAD 274
Cdd:PLN02988 166 EYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTfaSTILDAYTQHPRlKPQSAYHRLDVIDRCFSRR 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  275 SVEGILENLQNDGSE----WAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLE---RSDFKEGVRA 347
Cdd:PLN02988 246 TVEEIISALEREATQeadgWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKgeiSKDFVEGCRA 325
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 28381307  348 LLIDKDQKPQWQPTKLADVTEEHVQWFFRKLPDTEE 383
Cdd:PLN02988 326 ILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEE 361
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
35-382 7.21e-78

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 245.75  E-value: 7.21e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   35 TMALSVRQSSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVE 112
Cdd:PLN02157  27 SLKLTPEDLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIgfVMMKGSG-RAFCAGGDIVSLYH 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  113 ---AGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFL 189
Cdd:PLN02157 106 lrkRGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNL 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  190 PRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETAL--LNCPDADDVPELLQKYH--SPPEKPFSLQPVlE 265
Cdd:PLN02157 186 SHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLkkLLTDDPSVVESCLEKCAevAHPEKTGVIRRI-D 264
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  266 QINKNFSADSVEGILENLQNDGSE----WAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHL---ER 338
Cdd:PLN02157 265 LLEKCFSHDTVEEIIDSLEIEAGRrkdtWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLigpMS 344
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 28381307  339 SDFKEGVRALLIDKDQKPQWQPTKLADVTEEHVQWFFRKLPDTE 382
Cdd:PLN02157 345 GNFCEGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALTPTE 388
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
58-235 4.94e-51

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 169.28  E-value: 4.94e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGP-TDESKSFFREEYSTNALIG 134
Cdd:cd06558  12 ITLNRPEKRNALSLEMLDELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAALSDaGEEARAFIRELQELLRALL 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 135 NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVY 213
Cdd:cd06558  91 RLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELLLTGRRISAEEAL 170
                       170       180
                ....*....|....*....|..
gi 28381307 214 YSGIATHYCESSKIPDLETALL 235
Cdd:cd06558 171 ELGLVDEVVPDEELLAAALELA 192
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
58-349 3.72e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 153.40  E-value: 3.72e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 135
Cdd:COG1024  12 ITLNRPEKLNALSLEMLAELAAALDEAEADPDVrvVVLTGAG-KAFCAGADLKELAAAADPEEARAFARGLQRLFRALRR 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 136 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVYY 214
Cdd:COG1024  91 LPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELLLTGRRIDAEEALE 170
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 215 SGIATHYCESSkipdletallncpdaddvpELLQKyhsppekpfslqpvleqinknfsadsvegilenlqndgsewAKKT 294
Cdd:COG1024 171 LGLVNRVVPDD-------------------ELLAA-----------------------------------------ALAL 190
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*
gi 28381307 295 LETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALL 349
Cdd:COG1024 191 AARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
58-347 9.43e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 107.26  E-value: 9.43e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGP--TDESKSFFReeysTNALI 133
Cdd:PRK06688  18 ITINRPDKKNALTAAMYQALADALEAAATDPAVrvVVLTGAG-RAFSAGGDIKDFPKAPPkpPDELAPVNR----FLRAI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  134 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGklglylgltgyRLRGADVY 213
Cdd:PRK06688  93 AALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIG-----------RARAAEML 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  214 YSGiathycesskipdletallncpdaddvpellqkyhsppeKPFSLQPVLEQ--INKNFSADSVEGIlenlqndgsewA 291
Cdd:PRK06688 162 LLG---------------------------------------EPLSAEEALRIglVNRVVPAAELDAE-----------A 191
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 28381307  292 KKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRA 347
Cdd:PRK06688 192 DAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATA 247
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
44-204 1.86e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 103.68  E-value: 1.86e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   44 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVR---ALVEAGPTDE 118
Cdd:PRK05980   2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVraVILTGAGDRAFSAGADIHefsASVAAGADVA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  119 SKSFFREEYSTNALIGNYKIPYIAIIDGITMGGG--VGLSVHgkYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-K 195
Cdd:PRK05980  82 LRDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGceITEAVH--LAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrK 159

                 ....*....
gi 28381307  196 LGLYLGLTG 204
Cdd:PRK05980 160 RALELLLTG 168
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
50-217 2.69e-25

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 102.82  E-value: 2.69e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    50 TESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGtGDKAFCAGGDVRALVEAGPTDESKsfFREEY 127
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVraVVLTG-GDKAFCAGADLKEMYGEGPAHQAL--YRENV 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   128 STN-ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTGY 205
Cdd:pfam00378  78 LDLwTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLLGR 157
                         170
                  ....*....|..
gi 28381307   206 RLRGADVYYSGI 217
Cdd:pfam00378 158 RISAQEALKWGL 169
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
56-234 3.29e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 102.89  E-value: 3.29e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   56 GMIILNRPKALNAINLEMVRKIYKHLK--KCEKSKSLVIIKGTGDKAFCAGGDV--RALVEAGPTDESKSFFREeysTNA 131
Cdd:PRK07657  15 VKITLNRPRAANALSLALLEELQNILTqiNEEANVRVVILTGAGEKAFCAGADLkeRAGMNEEQVRHAVSLIRT---TME 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  132 LIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG----KLGLYlglTGYRL 207
Cdd:PRK07657  92 MVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGvgraKELIY---TGRRI 168
                        170       180
                 ....*....|....*....|....*..
gi 28381307  208 RGADVYYSGIATHYCESSKIpdLETAL 234
Cdd:PRK07657 169 SAQEAKEIGLVEFVVPAHLL--EEKAI 193
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
60-237 2.80e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 100.51  E-value: 2.80e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL-VIIKGTGDKAFCAGGDVRALVEAGPTDESKSffREEYSTNAlIGNYKI 138
Cdd:PRK08138  23 LNRPEARNALNMEVRQQLAEHFTELSEDPDIrAIVLTGGEKVFAAGADIKEFATAGAIEMYLR--HTERYWEA-IAQCPK 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  139 PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKL-GLYLGLTGYRLRGADVYYSGI 217
Cdd:PRK08138 100 PVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFkAMRMALTGCMVPAPEALAIGL 179
                        170       180
                 ....*....|....*....|
gi 28381307  218 ATHYCESSKIpdLETALLNC 237
Cdd:PRK08138 180 VSEVVEDEQT--LPRALELA 197
PLN02600 PLN02600
enoyl-CoA hydratase
60-222 3.60e-22

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 94.49  E-value: 3.60e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGDKAFCAGGDVRALVEAGPTdESKSFFREEYSTNALIGNYK 137
Cdd:PLN02600  10 LDRPEAKNAIGKEMLRGLRSAFEKIQAdaSARVVMLRSSVPGVFCAGADLKERRKMSPS-EVQKFVNSLRSTFSSLEALS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  138 IPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTGYRLRGADVYYSG 216
Cdd:PLN02600  89 IPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAKELIFTGRRIGAREAASMG 168

                 ....*.
gi 28381307  217 IAtHYC 222
Cdd:PLN02600 169 LV-NYC 173
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
54-204 2.05e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 92.15  E-value: 2.05e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   54 NKGM---IILNRPKALNAINLEMVRKIYKHLKKCEK--SKSLVIIKGTGdKAFCAGGDVRALVEAGPTDESKSFF---RE 125
Cdd:PRK06072   6 SREGyaiVTMSRPDKLNALNLEMRNEFISKLKQINAdpKIRVVIVTGEG-RAFCVGADLSEFAPDFAIDLRETFYpiiRE 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28381307  126 EYSTNalignyKIpYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTG 204
Cdd:PRK06072  85 IRFSD------KI-YISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLG 156
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
47-194 2.93e-20

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 89.42  E-value: 2.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   47 VLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTdESKSF-- 122
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVyaVILTGAGEKAFVAGADISEMKDLNEE-EGRKFgl 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28381307  123 -----FREeystnalIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK05809  85 lgnkvFRK-------LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVG 154
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
45-191 1.06e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 84.70  E-value: 1.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   45 SSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL-VIIKGTGdKAFCAGGDVRALVEagPTDESKsfF 123
Cdd:PRK07659   6 ESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAHiVVLRGNG-RGFSAGGDIKMMLS--SNDESK--F 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28381307  124 RE--EYSTNALIGNYKIP--YIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPR 191
Cdd:PRK07659  81 DGvmNTISEIVVTLYTMPklTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK 152
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
56-210 2.55e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 80.86  E-value: 2.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   56 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTgDKAFCAGGDVRALveagptdESKSF---FREEYSTN 130
Cdd:PRK05862  15 GLITLNRPKALNALNDALMDELGAALAAFDADEGIgaIVITGS-EKAFAAGADIKEM-------ADLSFmdvYKGDYITN 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  131 -ALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKL-GLYLGLTGyRLR 208
Cdd:PRK05862  87 wEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAkAMDLCLTG-RMM 165

                 ..
gi 28381307  209 GA 210
Cdd:PRK05862 166 DA 167
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
44-235 1.16e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 79.36  E-value: 1.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   44 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKS 121
Cdd:PRK06127  10 TGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIrvVVLTGAGEKAFVSGADISQFEESRSDAEAVA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  122 FFrEEYSTNA--LIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGsyfLPRLQGKLG-- 197
Cdd:PRK06127  90 AY-EQAVEAAqaALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDG---VKNLVDLVGps 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 28381307  198 --LYLGLTGYRLRGADVYYSGIATHYCESSkipDLETALL 235
Cdd:PRK06127 166 aaKDLFYTARRFDAAEALRIGLVHRVTAAD---DLETALA 202
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
58-207 2.50e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 78.16  E-value: 2.50e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKSFF---REEYSTNAl 132
Cdd:PRK06494  17 VTLNRPEVMNALHLDAHFELEEVFDDFAADPEQwvAIVTGAGDKAFSAGNDLKEQAAGGKRGWPESGFgglTSRFDLDK- 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28381307  133 ignykiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRL 207
Cdd:PRK06494  96 ------PIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGlKRAMGMILTGRRV 165
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
58-234 8.25e-16

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 76.66  E-value: 8.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDEsksffreEYSTNALIGN 135
Cdd:PRK03580  16 ITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELrvAIITGAGEKFFSAGWDLKAAAEGEAPDA-------DFGPGGFAGL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  136 YKI-----PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLP-RLQGKLGLYLGLTGYRLRG 209
Cdd:PRK03580  88 TEIfdldkPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPkRLPPAIANEMVMTGRRMDA 167
                        170       180
                 ....*....|....*....|....*
gi 28381307  210 ADVYYSGIATHYCESSKIPDLETAL 234
Cdd:PRK03580 168 EEALRWGIVNRVVPQAELMDRAREL 192
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
44-219 9.09e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 76.30  E-value: 9.09e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   44 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAgPTDESKS 121
Cdd:PRK05870   2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVhaLVVTGAG-KAFCAGADLTALGAA-PGRPAED 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  122 FFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYL 200
Cdd:PRK05870  80 GLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGpQVARAA 159
                        170
                 ....*....|....*....
gi 28381307  201 GLTGYRLRGADVYYSGIAT 219
Cdd:PRK05870 160 LLFGMRFDAEAAVRHGLAL 178
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
60-223 3.53e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 74.92  E-value: 3.53e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVeAGPTDESKSFF-REEYSTN----AL 132
Cdd:PRK07509  18 LNRPDKMNALDFAMFEELIATIKRLKKDRGIraVILSGEG-GAFCAGLDVKSVA-SSPGNAVKLLFkRLPGNANlaqrVS 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  133 IG--NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTGYRLRG 209
Cdd:PRK07509  96 LGwrRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKdVARELTYTARVFSA 175
                        170
                 ....*....|....
gi 28381307  210 ADVYYSGIATHYCE 223
Cdd:PRK07509 176 EEALELGLVTHVSD 189
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
72-208 1.79e-14

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 74.93  E-value: 1.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   72 EMVRKIYKHLKKCEKSKSLVIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGG 151
Cdd:PRK11154  37 EQVRAILKQLREDKELKGVVFISGKPD-NFIAGADINMLAACKTAQEAEALARQGQQLFAEIEALPIPVVAAIHGACLGG 115
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  152 GVGLSVHGKYRVASD--RTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLR 208
Cdd:PRK11154 116 GLELALACHYRVCTDdpKTVLGLPEVQLGLLPGSGGTQRLPRLIGvSTALDMILTGKQLR 175
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
56-347 3.80e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 71.69  E-value: 3.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   56 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALi 133
Cdd:PRK07260  13 ATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVrfLLINANG-KVFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEI- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  134 gNYKI-----PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRL 207
Cdd:PRK07260  91 -SFAIkqlpkPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGlNRATHLAMTGEAL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  208 RGADVYYSGIATHYCESSKipdLETALLNcpdaddvpellqkyhsppekpfslqpVLEQINKNfSADSVEGILENL-QND 286
Cdd:PRK07260 170 TAEKALEYGFVYRVAESEK---LEKTCEQ--------------------------LLKKLRRG-SSNSYAAIKSLVwESF 219
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28381307  287 GSEWAKktletlskmsptsmkvtFRQLELGSQLSLAQclimeyrlavrhleRSDFKEGVRA 347
Cdd:PRK07260 220 FKGWED-----------------YAKLELALQESLAF--------------KEDFKEGVRA 249
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
57-195 4.21e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 71.59  E-value: 4.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGDKaFCAGGDVRALVEAGPTDesksFFREEYSTNA---LI 133
Cdd:PRK08150  14 TIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVLHGEGDH-FCAGLDLSELRERDAGE----GMHHSRRWHRvfdKI 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28381307  134 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 195
Cdd:PRK08150  89 QYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGV 150
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
57-204 7.90e-14

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 70.57  E-value: 7.90e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVE----AGPTDESKSFFREeystn 130
Cdd:PRK09674  14 LLTLNRPEARNALNNALLTQLVNELEAAATDTSIgvCVITGNA-RFFAAGADLNEMAEkdlaATLNDPRPQLWQR----- 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28381307  131 alIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK-LGLYLGLTG 204
Cdd:PRK09674  88 --LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKsLASQMVLTG 160
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
58-195 2.18e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.50  E-value: 2.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 135
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIgvVILTGAGDKAFCSGGDQKVRGDYGYIDDSGVHRLNVLDVQRQIRT 95
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   136 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 195
Cdd:TIGR01929  96 CPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQ 155
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
42-217 2.84e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 68.95  E-value: 2.84e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   42 QSSSSVLATESSNKGMIILNRPkALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDV--RALVEAGPTD 117
Cdd:PRK06495   1 MMMSQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVrvVVLTGAG-KVFCAGADLkgRPDVIKGPGD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  118 ESKSFFREEYSTNALIGNYKiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLfpdVGGSYFLPRLQGK-L 196
Cdd:PRK06495  79 LRAHNRRTRECFHAIRECAK-PVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHsL 154
                        170       180
                 ....*....|....*....|.
gi 28381307  197 GLYLGLTGYRLRGADVYYSGI 217
Cdd:PRK06495 155 TRRMMLTGYRVPAAELYRRGV 175
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
60-194 3.27e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 69.23  E-value: 3.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAIN--------LEMVRKIYKhlkkcEKSKSLVIIKGTGdKAFCAGGDVRALVE-----AGPTDESksffREE 126
Cdd:PRK09245  18 MNRPETRNALSdndavdalVAACAAINA-----DRSVRAVILTGAG-TAFSSGGNVKDMRArvgafGGSPADI----RQG 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28381307  127 YSTN------ALIgNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK09245  88 YRHGiqriplALY-NLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIG 160
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
43-207 7.42e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 68.02  E-value: 7.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   43 SSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCE-KSKSLVIIKGTGdKAFCAG---GDVRALVEAGPTDE 118
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEdDGARALLLTGAG-RGFCAGqdlADRDVTPGGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  119 SKS---FFreeystNALI---GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRL 192
Cdd:PRK08140  81 GESietFY------NPLVrrlRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRL 154
                        170
                 ....*....|....*...
gi 28381307  193 QGK---LGlyLGLTGYRL 207
Cdd:PRK08140 155 VGMaraLG--LALLGEKL 170
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
58-194 1.30e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 67.72  E-value: 1.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAG------GDVRALVEAGPTDESKSFFREEYST 129
Cdd:PRK08260  17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVraVIVTGAG-RAFCAGadlsagGNTFDLDAPRTPVEADEEDRADPSD 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28381307  130 NAL----------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK08260  96 DGVrdgggrvtlrIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
58-189 1.82e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 66.87  E-value: 1.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGptdeskSFFREEYSTNAL--- 132
Cdd:PRK05995  17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVraVVLAGAG-KAFCAGADLNWMKKMA------GYSDDENRADARrla 89
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28381307  133 -----IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFL 189
Cdd:PRK05995  90 dmlraIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVI 151
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
58-220 2.18e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 66.54  E-value: 2.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTG-DKAFCAGGDvraLVEAGptDESKSFFREEYSTN--ALIG 134
Cdd:PRK06190  17 LTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGaDPAFCAGLD---LKELG--GDGSAYGAQDALPNpsPAWP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  135 NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVY 213
Cdd:PRK06190  92 AMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGiGRARRMSLTGDFLDAADAL 171

                 ....*..
gi 28381307  214 YSGIATH 220
Cdd:PRK06190 172 RAGLVTE 178
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
43-280 3.26e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 65.78  E-value: 3.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   43 SSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVeAG--PTDE 118
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLsvGILTGAG-GTFCAGMDLKAFA-RGerPSIP 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  119 SKSF--FREEYSTNalignykiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLP-RLQGK 195
Cdd:PRK08252  79 GRGFggLTERPPRK--------PLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPrRIPYH 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  196 LGLYLGLTGYRLRGADVYYSGIATHYCESSKIpdLETAL-------LNCPDA-DDVPELLQKYHS-PPEKPFSLQpvLEQ 266
Cdd:PRK08252 151 IAMELALTGDMLTAERAHELGLVNRLTEPGQA--LDAALelaeriaANGPLAvAASKRIVVESGDwSEDEMFARQ--REL 226
                        250
                 ....*....|....*
gi 28381307  267 INKNF-SADSVEGIL 280
Cdd:PRK08252 227 IAPVFtSADAKEGAT 241
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
58-173 3.44e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 66.17  E-value: 3.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAgptDESKSFFREEYSTNALIG- 134
Cdd:PRK06144  21 ITFNRPAARNAMTWAMYEGLAEICEAIAADPSIraVVLRGAGDKAFVAGTDIAQFRAF---STAEDAVAYERRIDRVLGa 97
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 28381307  135 --NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMP 173
Cdd:PRK06144  98 leQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
44-191 9.23e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 64.63  E-value: 9.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   44 SSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDkAFCAGGDVRALVEAGPTDESks 121
Cdd:PRK07511   2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIraVVLTGAGG-FFCAGGNLNRLLENRAKPPS-- 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28381307  122 fFREEySTNAL------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPR 191
Cdd:PRK07511  79 -VQAA-SIDGLhdwiraIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLAR 152
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
57-191 1.13e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 64.35  E-value: 1.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIG 134
Cdd:PRK07799  17 IVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIrsCILTGAGG-AFCAGMDLKAATKKPPGDSFKDGSYDPSRIDALLK 95
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  135 NYKI--PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPdVGGSYF-LPR 191
Cdd:PRK07799  96 GRRLtkPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVrLVR 154
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
46-211 2.76e-11

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 65.24  E-value: 2.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307    46 SVLATESSNKGMIILNrpKALNAinlEMVRKIyKHLKKCEKSKSLVIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFRE 125
Cdd:TIGR02441  24 AVVKIDSPNSKVNTLS--KELFA---EFKEVM-NELWTNEAIKSAVLISGKPG-SFVAGADIQMIAACKTAQEVTQLSQE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   126 EYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASD--RTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGL 202
Cdd:TIGR02441  97 GQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGvPAALDMML 176

                  ....*....
gi 28381307   203 TGYRLRgAD 211
Cdd:TIGR02441 177 TGKKIR-AD 184
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
91-195 2.04e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 60.82  E-value: 2.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   91 VIIKGTGDKAFCAGGDVRALVEAGPtDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLF 170
Cdd:PRK06143  55 LVLRGAGEKAFIGGADIKEMATLDQ-ASAEAFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQF 133
                         90       100
                 ....*....|....*....|....*
gi 28381307  171 AMPETAIGLfPDVGGSYFLPRLQGK 195
Cdd:PRK06143 134 GMPEVRVGI-PSVIHAALLPRLIGW 157
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
57-194 3.10e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 60.19  E-value: 3.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTgDKAFCAGGDVRALVEAGPTDESKS-----FFReeyst 129
Cdd:PRK06023  18 VIRFNRPEKKNAITRAMYATMAKALKAADADDAIraHVFLGT-EGCFSAGNDMQDFLAAAMGGTSFGseildFLI----- 91
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28381307  130 nALIGNYKiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK06023  92 -ALAEAEK-PIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMG 154
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
58-211 3.36e-10

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 60.30  E-value: 3.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSK--SLVIIKGTGDKaFCAGGDVRAL----VEAGPTDESKSFFREEYSTNA 131
Cdd:PLN02664  21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPnvSVIILSGAGDH-FCSGIDLKTLnsisEQSSSGDRGRSGERLRRKIKF 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  132 L------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGsyfLPRLQGKLG----LYLG 201
Cdd:PLN02664 100 LqdaitaIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGygnaMELA 176
                        170
                 ....*....|
gi 28381307  202 LTGYRLRGAD 211
Cdd:PLN02664 177 LTGRRFSGSE 186
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
60-204 3.76e-10

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 59.96  E-value: 3.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALvEAGPtdeSKSFFREEYSTNA----LI 133
Cdd:PRK08139  26 LNRPQAFNALSEAMLAALQAALDAIAADPSVrvVVLAAAG-KAFCAGHDLKEM-RAAR---GLAYFRALFARCSrvmqAI 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28381307  134 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF---PDVGGSYFLPRlqgKLGLYLGLTG 204
Cdd:PRK08139 101 VALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRNVPR---KQAMEMLLTG 171
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
56-195 4.08e-10

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 59.75  E-value: 4.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   56 GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLV---IIKGTGdKAFCAG----------GDVRALVEAGPTDES--K 120
Cdd:PRK05981  15 AILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAEVrclVLTGAG-RGFCTGanlqgrgsggRESDSGGDAGAALETayH 93
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28381307  121 SFFReeystnaLIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGK 195
Cdd:PRK05981  94 PFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGK 161
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
58-349 4.23e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 60.10  E-value: 4.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGD-KAFCAGGDVRALVEAGPTDESKSFFREEYSTN---ALI 133
Cdd:PRK06210  19 ITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAgRGFCAGADMGELQTIDPSDGRRDTDVRPFVGNrrpDYQ 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  134 GNYKI------PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYR 206
Cdd:PRK06210  99 TRYHFltalrkPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGhANALDLLLSART 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  207 LRGADVYYSGIATHYCESSKIpdLETALlncPDADDVpellqkyhsppekpfslqpvleqinknfsADSVegilenlqnd 286
Cdd:PRK06210 179 FYAEEALRLGLVNRVVPPDEL--MERTL---AYAEDL-----------------------------ARNV---------- 214
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28381307  287 gsewakktletlskmSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALL 349
Cdd:PRK06210 215 ---------------SPASMAVIKRQLYEDAFQTLAEATARANREMHESLQRPDFIEGVASFL 262
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
60-240 6.88e-10

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 59.05  E-value: 6.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSF--FRE--EYSTNalI 133
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLrfLLLRGRG-RHFSAGADLAWMQQSADLDYNTNLddARElaELMYN--L 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  134 GNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVY 213
Cdd:PRK05674  98 YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRRAR 177
                        170       180       190
                 ....*....|....*....|....*....|..
gi 28381307  214 YSGIATHYCESSKIPD-----LETALLNCPDA 240
Cdd:PRK05674 178 ELGLLAESYPAAELEAqveawIANLLLNSPQA 209
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
58-359 7.12e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 58.88  E-value: 7.12e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGN 135
Cdd:PRK07658  15 ITLNHPPA-NALSSQVLHELSELLDQVEKDDNVrvVVIHGEG-RFFSAGADIKEFTSVTEAEQATELAQLGQVTFERVEK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  136 YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKL-GLYLGLTGYRLRGADVYY 214
Cdd:PRK07658  93 FSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAkALEMMLTSEPITGAEALK 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  215 SGIATHycesskipdletallncpdADDVPELLQKyhsppekpfslqpvleqinknfsadsvegilenlqndgsewAKKT 294
Cdd:PRK07658 173 WGLVNG-------------------VFPEETLLDD-----------------------------------------AKKL 192
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28381307  295 LETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLidKDQKPQWQ 359
Cdd:PRK07658 193 AKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFL--EKRKPSFS 255
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
48-194 1.22e-09

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 59.88  E-value: 1.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   48 LATESSNKgmiilnrpkaLNAINLEMVRKIYKHLKKCEKSKSLVIikgTGDK-AFCAGGDVRALVE--AGPTDESKSFFR 124
Cdd:PRK11730  23 DAPGSVNK----------LDRATLASLGEALDALEAQSDLKGLLL---TSAKdAFIVGADITEFLSlfAAPEEELSQWLH 89
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28381307  125 EEYST-NALiGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK11730  90 FANSIfNRL-EDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
34-206 3.09e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 57.38  E-value: 3.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   34 TTMALSVRQSSSSVLATessnkgmIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRALV 111
Cdd:PRK07827   2 TPVDTLVRYAVDGGVAT-------LTLDSPHNRNALSARLVAQLHDGLRAAAADPAVraVVLTHTG-GTFCAGADLSEAG 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  112 EAGPTDESKSFFREEYSTNAL--IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFL 189
Cdd:PRK07827  74 GGGGDPYDAAVARAREMTALLraIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLL 153
                        170
                 ....*....|....*...
gi 28381307  190 PRLQGK-LGLYLgLTGYR 206
Cdd:PRK07827 154 PRLSPRaAARYY-LTGEK 170
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
58-201 3.33e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 57.28  E-value: 3.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEM---VRKIYKHLKKCEKSKSLVIiKGTGDkAFCAGGDVRALVeaGP-----TDESKSFFReeyST 129
Cdd:PRK08258  30 ITLNRPERKNPLTFESyaeLRDLFRELVYADDVKAVVL-TGAGG-NFCSGGDVHEII--GPltkmdMPELLAFTR---MT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  130 NALIG---NYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF-PDVGGSYFLPRLQGkLG-----LYL 200
Cdd:PRK08258 103 GDLVKamrACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRIIG-QGraselLYT 181

                 .
gi 28381307  201 G 201
Cdd:PRK08258 182 G 182
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
57-359 7.05e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 56.08  E-value: 7.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEA--GPTDESKSFFREEYSTnal 132
Cdd:PRK09076  15 ILTLNNPPA-NTWTADSLQALKQLVLELNADKDVyaLVITGDGEKFFSAGADLNLFADGdkAVAREMARRFGEAFEA--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  133 IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKlglylG------LTGYR 206
Cdd:PRK09076  91 LSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGE-----GwakrmiLCGER 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  207 LrgadvyysgiathycesskipDLETAL---LncpdaddVPELLqkyhsppEKPFSLQPVLeqinknfsadsvegilenl 283
Cdd:PRK09076 166 V---------------------DAATALrigL-------VEEVV-------EKGEAREAAL------------------- 191
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28381307  284 qndgsEWAKKtletLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLiDKdQKPQWQ 359
Cdd:PRK09076 192 -----ALAQK----VANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFL-EK-RAPQWK 256
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
60-192 8.11e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 55.84  E-value: 8.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   60 LNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGdKAFCAGGDV---RALVEAGPTDESKSFFREEYSTNALIG 134
Cdd:PRK07468  20 LNRPEKHNALSARMIAELTTAARRLAADAAvrVVVLTGAG-KSFCAGGDLgwmRAQMTADRATRIEEARRLAMMLKALND 98
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 28381307  135 NYKiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRL 192
Cdd:PRK07468  99 LPK-PLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARM 155
PLN02888 PLN02888
enoyl-CoA hydratase
42-194 2.96e-08

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 54.37  E-value: 2.96e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   42 QSSSSVLATESSNKGMII-LNRPKALNAINLEMVRKIYKHLKKC--EKSKSLVIIKGTGdKAFCAGGDVRAlveagPTDE 118
Cdd:PLN02888   6 VSENLILVPKSRNGIATItINRPKALNALTRPMMVELAAAFKRLdeDDSVKVIILTGSG-RAFCSGVDLTA-----AEEV 79
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28381307  119 SKSFFR-EEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PLN02888  80 FKGDVKdVETDPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIG 156
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
57-194 5.98e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 53.68  E-value: 5.98e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRAlveAGPTDESKSFFREEYSTNAL-- 132
Cdd:PRK05864  22 LITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVrvVVLTGAG-RGFSSGADHKS---AGVVPHVEGLTRPTYALRSMel 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  133 -------IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF-PDVGGSYFLPRLQG 194
Cdd:PRK05864  98 lddvilaLRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLSYLLPRAIG 167
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
54-181 1.89e-07

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 51.61  E-value: 1.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   54 NKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGDkAFCAGGDVRALVEAGPTDESKSFFREEYstnali 133
Cdd:PRK07112  13 DVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVLEGLPE-VFCFGADFSAIAEKPDAGRADLIDAEPL------ 85
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 28381307  134 gnYKI-------PYIAI--IDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFP 181
Cdd:PRK07112  86 --YDLwhrlatgPYVTIahVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP 140
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
50-179 2.46e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 51.18  E-value: 2.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   50 TESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVI-IKGTGdKAFCAGGDVRALVEAgptdesKSFFREEYS 128
Cdd:PRK07854   5 TRDGQVLTIELQRPERRNALNAELCEELREAVRKAVDESARAIvLTGQG-TVFCAGADLSGDVYA------DDFPDALIE 77
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 28381307  129 TNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGL 179
Cdd:PRK07854  78 MLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGI 128
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
67-211 4.63e-07

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 50.35  E-value: 4.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   67 NAINLEMVRKIYKHLKKCEKSKSL--VIIKGTgDKAFCAGGDVRALVEAgpTDESKSFFREEYSTNALigNYKIPYIAII 144
Cdd:PRK07110  27 NAFSDELCDQLHEAFDTIAQDPRYkvVILTGY-PNYFATGGTQEGLLSL--QTGKGTFTEANLYSLAL--NCPIPVIAAM 101
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28381307  145 DGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRlqgKLGLYLG----LTGYRLRGAD 211
Cdd:PRK07110 102 QGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPE---KLGLALGqemlLTARYYRGAE 169
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
58-194 1.29e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 49.20  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGdKAFCAGGDVRAL------VEAGPTDESKSFFREEY-- 127
Cdd:PRK06142  19 VTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVraVVLSGSG-KHFSYGIDLPAMagvfgqLGKDGLARPRTDLRREIlr 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  128 ---STNAlIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK06142  98 lqaAINA-VADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIG 166
PLN02921 PLN02921
naphthoate synthase
58-194 2.37e-06

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 49.02  E-value: 2.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKC--EKSKSLVIIKGTGDKAFCAGGDvRALVEAGPTDESKSFFReeysTNALIGN 135
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDArdDSSVGVIILTGKGTKAFCSGGD-QAVRGKDGYVGPDDAGR----LNVLDLQ 154
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28381307  136 YKI-----PYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFpDVG-GSYFLPRLQG 194
Cdd:PLN02921 155 IQIrrlpkPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVG 218
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
58-194 4.01e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 47.97  E-value: 4.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDESK-------SFFReeys 128
Cdd:PRK07396  26 ITINRPEVRNAFRPKTVKEMIDAFADARDDDNIgvIILTGAGDKAFCSGGDQKVRGYGGYVDDDGvprlnvlDLQR---- 101
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28381307  129 tnaLIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFpDVG-GSYFLPRLQG 194
Cdd:PRK07396 102 ---LIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSF-DGGyGASYLARIVG 164
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
40-194 5.17e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 47.14  E-value: 5.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   40 VRQSSSSVLATESSNKG--MIILNRPKAlNAINLEMVRKIYKHLKKCEKSKSL--VIIKGtGDKAFCAGGDVRAL----- 110
Cdd:PRK05869   1 MNEFVNVVVSDGSQDAGlaTLLLSRPPT-NALTRQVYREIVAAANELGRRDDVaaVILYG-GHEIFSAGDDMPELrtlsa 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  111 VEAGPTDESKsffREEYSTNALIGNykiPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLP 190
Cdd:PRK05869  79 QEADTAARVR---QQAVDAVAAIPK---PTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLT 152

                 ....
gi 28381307  191 RLQG 194
Cdd:PRK05869 153 RAAG 156
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
57-194 2.43e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 45.34  E-value: 2.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKaFCAGGDvraLVEAGPTDESKSFFREEYSTN--AL 132
Cdd:PRK06563  11 LIGLDRPAKRNAFDSAMLDDLALALGEYEADDELrvAVLFAHGEH-FTAGLD---LADVAPKLAAGGFPFPEGGIDpwGT 86
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28381307  133 IGN-YKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG 194
Cdd:PRK06563  87 VGRrLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAG 149
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
43-234 7.80e-05

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 43.86  E-value: 7.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   43 SSSSVLATESSNK-GMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVII--KGTGDKAFCAGGDVRALVEAG--PTD 117
Cdd:PRK11423   1 MSMQYVNVVTINKiATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVIlrAPSGSKVWSAGHDIHELPSGGrdPLS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  118 ESKSFfreEYSTNAlIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGsyfLPRLQGKLG 197
Cdd:PRK11423  81 YDDPL---RQILRM-IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTNDAG 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 28381307  198 LYLG----LTGYRLRGADVYYSGIATHYCESSKIPDLETAL 234
Cdd:PRK11423 154 FHIVkemfFTASPITAQRALAVGILNHVVEVEELEDFTLQM 194
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
91-192 1.06e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 43.42  E-value: 1.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307   91 VIIKGTGdKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLF 170
Cdd:PRK07938  49 VVLRAEG-RGFNAGVDIKELQATPGFTALIDANRGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATF 127
                         90       100
                 ....*....|....*....|..
gi 28381307  171 AMPETAIGLfpdVGGSYFLPRL 192
Cdd:PRK07938 128 GLPEVDRGA---LGAATHLQRL 146
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
58-117 1.09e-03

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 40.39  E-value: 1.09e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28381307   58 IILNRPKALNAINLEMVR---KIYKHLKKcEKSKSLVIIKGTGdKAFCAGGDVrALVEAGPTD 117
Cdd:PRK07327  25 IVLNGPGALNAADARMHRelaDIWRDVDR-DPDVRVVLIRGEG-KAFSAGGDL-ALVEEMADD 84
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
58-194 1.19e-03

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 40.19  E-value: 1.19e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307  58 IILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDK-----AFCAGGDVRALVEAGPTDESKsffreeystn 130
Cdd:COG0447  31 IAINRPEVRNAFRPETVDELYDALDHAREDPDVgvVLLTGNGPSkdggwAFCSGGDQRVRGRGGYVYEDG---------- 100
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28381307 131 alIGNYKI------------PYIAIIDGITMGGgvGLSVHgkyrVASDRTLFAmpETAIglF----PDVG------GSYF 188
Cdd:COG0447 101 --VGRLNIlevqrlirfmpkPVIAMVAGWAIGG--GHVLH----VVCDLTIAS--ENAR--FgqtgPDVGsfdagyGSAY 168

                ....*.
gi 28381307 189 LPRLQG 194
Cdd:COG0447 169 LARQVG 174
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
58-114 4.77e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 38.48  E-value: 4.77e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 28381307   58 IILNRPKALNAINLEMVRKIYKHLKKCE--KSKSLVIIKGTGdKAFCAGGDVRALVEAG 114
Cdd:PRK08272  23 ITLNRPEKGNAITADTPLELRAAVERADldPGVHVILVSGAG-KGFCAGYDLSAYAEGS 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH