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Conserved domains on  [gi|22655406|gb|AAM98295|]
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At3g50440/T20E23_40 [Arabidopsis thaliana]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
22-267 7.98e-51

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02965:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 255  Bit Score: 167.40  E-value: 7.98e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   22 FVFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEPLMSFMESLPENEKVVLVGHSYGGIG 101
Cdd:PLN02965   6 FVFVHGASHGAWCWYKLATLLDAAGFKSTCVDLTGAGISLTDSNTVSSSDQYNRPLFALLSDLPPDHKVILVGHSIGGGS 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  102 TSLAMERFPTKVSVGIFLSAYMPHhdspPAVLIQEYFTRLPEGFAMDCEFTFEEGLEHPPSSVLFGTSFLKEKAYSNCQL 181
Cdd:PLN02965  86 VTEALCKFTDKISMAIYVAAAMVK----PGSIISPRLKNVMEGTEKIWDYTFGEGPDKPPTGIMMKPEFVRHYYYNQSPL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  182 EDLELAMALMKPSWLYTKEmGGEDLITKERYGSGKRVFIVCEGDNVVPEEIQKWMISNYEPHEVKRIEEAGHMAMLTKPH 261
Cdd:PLN02965 162 EDYTLSSKLLRPAPVRAFQ-DLDKLPPNPEAEKVPRVYIKTAKDNLFDPVRQDVMVENWPPAQTYVLEDSDHSAFFSVPT 240

                 ....*.
gi 22655406  262 ELSQLL 267
Cdd:PLN02965 241 TLFQYL 246
 
Name Accession Description Interval E-value
PLN02965 PLN02965
Probable pheophorbidase
22-267 7.98e-51

Probable pheophorbidase


Pssm-ID: 178549 [Multi-domain]  Cd Length: 255  Bit Score: 167.40  E-value: 7.98e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   22 FVFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEPLMSFMESLPENEKVVLVGHSYGGIG 101
Cdd:PLN02965   6 FVFVHGASHGAWCWYKLATLLDAAGFKSTCVDLTGAGISLTDSNTVSSSDQYNRPLFALLSDLPPDHKVILVGHSIGGGS 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  102 TSLAMERFPTKVSVGIFLSAYMPHhdspPAVLIQEYFTRLPEGFAMDCEFTFEEGLEHPPSSVLFGTSFLKEKAYSNCQL 181
Cdd:PLN02965  86 VTEALCKFTDKISMAIYVAAAMVK----PGSIISPRLKNVMEGTEKIWDYTFGEGPDKPPTGIMMKPEFVRHYYYNQSPL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  182 EDLELAMALMKPSWLYTKEmGGEDLITKERYGSGKRVFIVCEGDNVVPEEIQKWMISNYEPHEVKRIEEAGHMAMLTKPH 261
Cdd:PLN02965 162 EDYTLSSKLLRPAPVRAFQ-DLDKLPPNPEAEKVPRVYIKTAKDNLFDPVRQDVMVENWPPAQTYVLEDSDHSAFFSVPT 240

                 ....*.
gi 22655406  262 ELSQLL 267
Cdd:PLN02965 241 TLFQYL 246
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
22-266 6.28e-18

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 79.83  E-value: 6.28e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406    22 FVFVHGSCHGAWCWFKLAAklklDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEplmsFMESLPENEKVVLVGHSYGGIg 101
Cdd:pfam12697   1 VVLVHGAGLSAAPLAALLA----AGVAVLAPDLPGHGSSSPPPLDLADLADLAA----LLDELGAARPVVLVGHSLGGA- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   102 tsLAMERFPTKVSVGIFLSAYMPHHDSPPAVLiqEYFTRLPEGFAmdcEFTFEEGLEHPPssvlfgtSFLKEKAYsncqL 181
Cdd:pfam12697  72 --VALAAAAAALVVGVLVAPLAAPPGLLAALL--ALLARLGAALA---APAWLAAESLAR-------GFLDDLPA----D 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   182 EDLELAMALMKPSWLYTKEMGGEDLITKerygsGKRVFIVCEGDNVVPEEIQKWMiSNYEPHEVKRIEEAGHMAMLTkPH 261
Cdd:pfam12697 134 AEWAAALARLAALLAALALLPLAAWRDL-----PVPVLVLAEEDRLVPELAQRLL-AALAGARLVVLPGAGHLPLDD-PE 206

                  ....*
gi 22655406   262 ELSQL 266
Cdd:pfam12697 207 EVAEA 211
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
23-273 5.23e-16

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 75.04  E-value: 5.23e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  23 VFVHGSCHGAWCWFKLAAKLKlDGHRVTAIDLGGSGvDTRQLHEVRLVSAYLEPLMSFMESLPEnEKVVLVGHSYGGIGT 102
Cdd:COG0596  27 VLLHGLPGSSYEWRPLIPALA-AGYRVIAPDLRGHG-RSDKPAGGYTLDDLADDLAALLDALGL-ERVVLVGHSMGGMVA 103
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406 103 SLAMERFPTKVSvGIflsaymphhdsppaVLIQEYFTRLPEGFAMDceftfeeglEHPPSSVLfgtsflkeKAYSNCQLE 182
Cdd:COG0596 104 LELAARHPERVA-GL--------------VLVDEVLAALAEPLRRP---------GLAPEALA--------ALLRALART 151
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406 183 DLELAMALMK-PSWLytkemggedlitkerygsgkrvfIVCEGDNVVPEEIQKWMISNYEPHEVKRIEEAGHMAMLTKPH 261
Cdd:COG0596 152 DLRERLARITvPTLV-----------------------IWGEKDPIVPPALARRLAELLPNAELVVLPGAGHFPPLEQPE 208
                       250
                ....*....|..
gi 22655406 262 ELSQLLQEIAAK 273
Cdd:COG0596 209 AFAAALRDFLAR 220
 
Name Accession Description Interval E-value
PLN02965 PLN02965
Probable pheophorbidase
22-267 7.98e-51

Probable pheophorbidase


Pssm-ID: 178549 [Multi-domain]  Cd Length: 255  Bit Score: 167.40  E-value: 7.98e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   22 FVFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEPLMSFMESLPENEKVVLVGHSYGGIG 101
Cdd:PLN02965   6 FVFVHGASHGAWCWYKLATLLDAAGFKSTCVDLTGAGISLTDSNTVSSSDQYNRPLFALLSDLPPDHKVILVGHSIGGGS 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  102 TSLAMERFPTKVSVGIFLSAYMPHhdspPAVLIQEYFTRLPEGFAMDCEFTFEEGLEHPPSSVLFGTSFLKEKAYSNCQL 181
Cdd:PLN02965  86 VTEALCKFTDKISMAIYVAAAMVK----PGSIISPRLKNVMEGTEKIWDYTFGEGPDKPPTGIMMKPEFVRHYYYNQSPL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  182 EDLELAMALMKPSWLYTKEmGGEDLITKERYGSGKRVFIVCEGDNVVPEEIQKWMISNYEPHEVKRIEEAGHMAMLTKPH 261
Cdd:PLN02965 162 EDYTLSSKLLRPAPVRAFQ-DLDKLPPNPEAEKVPRVYIKTAKDNLFDPVRQDVMVENWPPAQTYVLEDSDHSAFFSVPT 240

                 ....*.
gi 22655406  262 ELSQLL 267
Cdd:PLN02965 241 TLFQYL 246
PLN02211 PLN02211
methyl indole-3-acetate methyltransferase
22-272 9.56e-43

methyl indole-3-acetate methyltransferase


Pssm-ID: 215128  Cd Length: 273  Bit Score: 146.96  E-value: 9.56e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   22 FVFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEPLMSFMESLPENEKVVLVGHSYGGIG 101
Cdd:PLN02211  21 FVLIHGISGGSWCWYKIRCLMENSGYKVTCIDLKSAGIDQSDADSVTTFDEYNKPLIDFLSSLPENEKVILVGHSAGGLS 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  102 TSLAMERFPTKVSVGIFLSAYMPHHDSPPAVLIQEYFTRLPEgFAMDCEFTFEEGLEHPPSSVLFGTSFLKEKAYSNCQL 181
Cdd:PLN02211 101 VTQAIHRFPKKICLAVYVAATMLKLGFQTDEDMKDGVPDLSE-FGDVYELGFGLGPDQPPTSAIIKKEFRRKILYQMSPQ 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  182 EDLELAMALMKPSWL-------YTKEMGGEDLITkerygsgkRVFIVCEGDNVVPEEIQKWMISNYEPHEVKRIeEAGHM 254
Cdd:PLN02211 180 EDSTLAAMLLRPGPIlalrsarFEEETGDIDKVP--------RVYIKTLHDHVVKPEQQEAMIKRWPPSQVYEL-ESDHS 250
                        250
                 ....*....|....*...
gi 22655406  255 AMLTKPHELSQLLQEIAA 272
Cdd:PLN02211 251 PFFSTPFLLFGLLIKAAA 268
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
22-266 6.28e-18

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 79.83  E-value: 6.28e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406    22 FVFVHGSCHGAWCWFKLAAklklDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEplmsFMESLPENEKVVLVGHSYGGIg 101
Cdd:pfam12697   1 VVLVHGAGLSAAPLAALLA----AGVAVLAPDLPGHGSSSPPPLDLADLADLAA----LLDELGAARPVVLVGHSLGGA- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   102 tsLAMERFPTKVSVGIFLSAYMPHHDSPPAVLiqEYFTRLPEGFAmdcEFTFEEGLEHPPssvlfgtSFLKEKAYsncqL 181
Cdd:pfam12697  72 --VALAAAAAALVVGVLVAPLAAPPGLLAALL--ALLARLGAALA---APAWLAAESLAR-------GFLDDLPA----D 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   182 EDLELAMALMKPSWLYTKEMGGEDLITKerygsGKRVFIVCEGDNVVPEEIQKWMiSNYEPHEVKRIEEAGHMAMLTkPH 261
Cdd:pfam12697 134 AEWAAALARLAALLAALALLPLAAWRDL-----PVPVLVLAEEDRLVPELAQRLL-AALAGARLVVLPGAGHLPLDD-PE 206

                  ....*
gi 22655406   262 ELSQL 266
Cdd:pfam12697 207 EVAEA 211
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
22-260 2.14e-17

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 79.09  E-value: 2.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406    22 FVFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYL-EPLMSFMESLPeNEKVVLVGHSYGG- 99
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLaEDLEYILEALG-LEKVNLVGHSMGGl 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   100 IGTSLAmERFPTKVSVGIFLSAYMPHHDSPPAVLIQ-EYFTRLPEGFAMDCEFTFEE-GLEHPPSSVLFGTSFLKEKA-- 175
Cdd:pfam00561  82 IALAYA-AKYPDRVKALVLLGALDPPHELDEADRFIlALFPGFFDGFVADFAPNPLGrLVAKLLALLLLRLRLLKALPll 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406   176 YSNCQLEDLELAMALMKPSWLYTKEMGGEDLITKERYGSGKRVFIVCEGDNVVPEEiQKWMISNYEPHE-VKRIEEAGHM 254
Cdd:pfam00561 161 NKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRLDEPTLIIWGDQDPLVPPQ-ALEKLAQLFPNArLVVIPDAGHF 239

                  ....*.
gi 22655406   255 AMLTKP 260
Cdd:pfam00561 240 AFLEGP 245
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
23-273 5.23e-16

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 75.04  E-value: 5.23e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  23 VFVHGSCHGAWCWFKLAAKLKlDGHRVTAIDLGGSGvDTRQLHEVRLVSAYLEPLMSFMESLPEnEKVVLVGHSYGGIGT 102
Cdd:COG0596  27 VLLHGLPGSSYEWRPLIPALA-AGYRVIAPDLRGHG-RSDKPAGGYTLDDLADDLAALLDALGL-ERVVLVGHSMGGMVA 103
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406 103 SLAMERFPTKVSvGIflsaymphhdsppaVLIQEYFTRLPEGFAMDceftfeeglEHPPSSVLfgtsflkeKAYSNCQLE 182
Cdd:COG0596 104 LELAARHPERVA-GL--------------VLVDEVLAALAEPLRRP---------GLAPEALA--------ALLRALART 151
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406 183 DLELAMALMK-PSWLytkemggedlitkerygsgkrvfIVCEGDNVVPEEIQKWMISNYEPHEVKRIEEAGHMAMLTKPH 261
Cdd:COG0596 152 DLRERLARITvPTLV-----------------------IWGEKDPIVPPALARRLAELLPNAELVVLPGAGHFPPLEQPE 208
                       250
                ....*....|..
gi 22655406 262 ELSQLLQEIAAK 273
Cdd:COG0596 209 AFAAALRDFLAR 220
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
23-134 1.67e-11

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 62.33  E-value: 1.67e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  23 VFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLHEVRLVSAYLEPLMSFMESLPE--NEKVVLVGHSYGGI 100
Cdd:COG2267  32 VLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAALDALRArpGLPVVLLGHSMGGL 111
                        90       100       110
                ....*....|....*....|....*....|....
gi 22655406 101 GTSLAMERFPTKVSvGIFLSAymPHHDSPPAVLI 134
Cdd:COG2267 112 IALLYAARYPDRVA-GLVLLA--PAYRADPLLGP 142
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
23-126 2.17e-11

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 59.46  E-value: 2.17e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  23 VFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGVDTRQLheVRLVSAYLEPLMsfmeSLPENEKVVLVGHSYGGIGT 102
Cdd:COG1075   9 VLVHGLGGSAASWAPLAPRLRAAGYPVYALNYPSTNGSIEDS--AEQLAAFVDAVL----AATGAEKVDLVGHSMGGLVA 82
                        90       100
                ....*....|....*....|....*.
gi 22655406 103 SLAMERF--PTKVSVGIFLSAymPHH 126
Cdd:COG1075  83 RYYLKRLggAAKVARVVTLGT--PHH 106
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
23-147 1.00e-05

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 45.67  E-value: 1.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406    23 VFVHGSCHGAWCWFKLAAKLKLDGHRVTAIDLGGSGV-DTRQLHeVRLVSAYLEPLMSFMESLPE---NEKVVLVGHSYG 98
Cdd:pfam12146   8 VLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRsDGKRGH-VPSFDDYVDDLDTFVDKIREehpGLPLFLLGHSMG 86
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 22655406    99 GIGTSLAMERFPTKVSvGIFLSAymphhdspPAVLIQEYFTRLPEGFAM 147
Cdd:pfam12146  87 GLIAALYALRYPDKVD-GLILSA--------PALKIKPYLAPPILKLLA 126
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
23-122 1.18e-05

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 45.39  E-value: 1.18e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406  23 VFVHGSCHGAWCWFKLAAK-LKLDGHRVTAIDLGGSGVDTRQLHEVRLvsAYLEPLMSFMESLPE--NEKVVLVGHSYGG 99
Cdd:COG1506  27 VYVHGGPGSRDDSFLPLAQaLASRGYAVLAPDYRGYGESAGDWGGDEV--DDVLAAIDYLAARPYvdPDRIGIYGHSYGG 104
                        90       100
                ....*....|....*....|...
gi 22655406 100 IGTSLAMERFPTKVSVGIFLSAY 122
Cdd:COG1506 105 YMALLAAARHPDRFKAAVALAGV 127
PGAP1 pfam07819
PGAP1-like protein; The sequences found in this family are similar to PGAP1. This is an ...
23-141 3.16e-04

PGAP1-like protein; The sequences found in this family are similar to PGAP1. This is an endoplasmic reticulum membrane protein with a catalytic serine containing motif that is conserved in a number of lipases. PGAP1 functions as a GPI inositol-deacylase; this deacylation is important for the efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi body. This entry also includes Tgl2, a mitochondria protein that serves as a triacylglycerol lipase in budding yeasts.


Pssm-ID: 369540  Cd Length: 233  Bit Score: 41.20  E-value: 3.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22655406    23 VFVHGSCHGAWCWFKLAAKLKLD--GHRVT------------AIDLGG--SGVDTRQLHE----VRLVSAYLEPLMSfmE 82
Cdd:pfam07819   8 LFIPGNAGSYKQVRSIASVAANLyqVLRKLlqndngfhldffSVDFNEelSAFHGRTLLDqaeyLNDAIRYILSLYA--S 85
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 22655406    83 SLPENEKVVLVGHSYGGIGTSLAM---ERFPTKVSVGIFLSAymPHHdSPPAVL---IQEYFTRL 141
Cdd:pfam07819  86 GRPGPTSVILIGHSMGGIVARAALtlpNYIPQSVNTIITLSS--PHA-KPPLTFdgdILKFYERL 147
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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