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Conserved domains on  [gi|28380870|gb|AAM68705|]
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uncharacterized protein Dmel_CG30036 [Drosophila melanogaster]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229488)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Galactosyl_T super family cl21608
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 72-329 1.86e-40

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


The actual alignment was detected with superfamily member pfam01762:

Pssm-ID: 473923 [Multi-domain]  Cd Length: 195  Bit Score: 141.69  E-value: 1.86e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870    72 EQRSAIRQTWGNTKSFNYGEfvrlhghlegkylsvmpgrlklysmylsglddsltakIRIVFILGRSKNDSKRELDKLFR 151
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGR-------------------------------------IKSLFLVGLSADTDGKVADLVME 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   152 ESIQHNDIIQENFVDSYHNLTLKSVMALKHISqSCADRAAFFLKCDDDTFVNVPNLLHFLLGGTIPlykdtvgyhsrtty 231
Cdd:pfam01762  44 EAKLYGDIVVVDFEDTYENLTFKTLTGLLWAV-SKCPSAKYIGKIDDDVYFFPDKLLSLLDNGNID-------------- 108

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   232 kVKSPWnrlngsrglMYGHKFCNMKTVDDVKSPWYMPYYMFKGAKYPKYLSGTGYLMSIDVVKRLYAEALTTSLVHLEDV 311
Cdd:pfam01762 109 -PSESS---------FYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAAEKLLKASKHRRFLQIEDV 178

                         250
                  ....*....|....*...
gi 28380870   312 FVtGICAKKAGIRRRHQP 329
Cdd:pfam01762 179 YV-GILANDLGISRVNLP 195
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 72-329 1.86e-40

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 141.69  E-value: 1.86e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870    72 EQRSAIRQTWGNTKSFNYGEfvrlhghlegkylsvmpgrlklysmylsglddsltakIRIVFILGRSKNDSKRELDKLFR 151
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGR-------------------------------------IKSLFLVGLSADTDGKVADLVME 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   152 ESIQHNDIIQENFVDSYHNLTLKSVMALKHISqSCADRAAFFLKCDDDTFVNVPNLLHFLLGGTIPlykdtvgyhsrtty 231
Cdd:pfam01762  44 EAKLYGDIVVVDFEDTYENLTFKTLTGLLWAV-SKCPSAKYIGKIDDDVYFFPDKLLSLLDNGNID-------------- 108

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   232 kVKSPWnrlngsrglMYGHKFCNMKTVDDVKSPWYMPYYMFKGAKYPKYLSGTGYLMSIDVVKRLYAEALTTSLVHLEDV 311
Cdd:pfam01762 109 -PSESS---------FYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAAEKLLKASKHRRFLQIEDV 178

                         250
                  ....*....|....*...
gi 28380870   312 FVtGICAKKAGIRRRHQP 329
Cdd:pfam01762 179 YV-GILANDLGISRVNLP 195
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 60-297 2.18e-11

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 65.21  E-value: 2.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   60 LVIAVCSGLDHFEQRSAIRQTWGntksfnygefvrlhghlegKYLSVMPGRlklysmylsglddsltAKIRivFILGRSK 139
Cdd:PLN03133 387 LFIGVFSTANNFKRRMAVRRTWM-------------------QYDAVRSGA----------------VAVR--FFVGLHK 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870  140 NDSKREldKLFRESIQHNDIIQENFVDSYHNLTLKSVMALkhISQSCADRAAFFLKCDDDTFVNVPNLLHFLlggtiply 219
Cdd:PLN03133 430 NQMVNE--ELWNEARTYGDIQLMPFVDYYSLITWKTLAIC--IFGTEVVSAKYVMKTDDDAFVRVDEVLASL-------- 497

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28380870  220 kdtvgyhsrttykvkspwNRLNGSRGLMYGHKFCNMKTVDDVKSPWYMPYYMFKGAKYPKYLSGTGYLMSIDVVKRLY 297
Cdd:PLN03133 498 ------------------KRTNVSHGLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVVSRDIAKEVY 557
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 72-329 1.86e-40

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 141.69  E-value: 1.86e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870    72 EQRSAIRQTWGNTKSFNYGEfvrlhghlegkylsvmpgrlklysmylsglddsltakIRIVFILGRSKNDSKRELDKLFR 151
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGR-------------------------------------IKSLFLVGLSADTDGKVADLVME 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   152 ESIQHNDIIQENFVDSYHNLTLKSVMALKHISqSCADRAAFFLKCDDDTFVNVPNLLHFLLGGTIPlykdtvgyhsrtty 231
Cdd:pfam01762  44 EAKLYGDIVVVDFEDTYENLTFKTLTGLLWAV-SKCPSAKYIGKIDDDVYFFPDKLLSLLDNGNID-------------- 108

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   232 kVKSPWnrlngsrglMYGHKFCNMKTVDDVKSPWYMPYYMFKGAKYPKYLSGTGYLMSIDVVKRLYAEALTTSLVHLEDV 311
Cdd:pfam01762 109 -PSESS---------FYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDAAEKLLKASKHRRFLQIEDV 178

                         250
                  ....*....|....*...
gi 28380870   312 FVtGICAKKAGIRRRHQP 329
Cdd:pfam01762 179 YV-GILANDLGISRVNLP 195
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 60-297 2.18e-11

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 65.21  E-value: 2.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870   60 LVIAVCSGLDHFEQRSAIRQTWGntksfnygefvrlhghlegKYLSVMPGRlklysmylsglddsltAKIRivFILGRSK 139
Cdd:PLN03133 387 LFIGVFSTANNFKRRMAVRRTWM-------------------QYDAVRSGA----------------VAVR--FFVGLHK 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28380870  140 NDSKREldKLFRESIQHNDIIQENFVDSYHNLTLKSVMALkhISQSCADRAAFFLKCDDDTFVNVPNLLHFLlggtiply 219
Cdd:PLN03133 430 NQMVNE--ELWNEARTYGDIQLMPFVDYYSLITWKTLAIC--IFGTEVVSAKYVMKTDDDAFVRVDEVLASL-------- 497

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28380870  220 kdtvgyhsrttykvkspwNRLNGSRGLMYGHKFCNMKTVDDVKSPWYMPYYMFKGAKYPKYLSGTGYLMSIDVVKRLY 297
Cdd:PLN03133 498 ------------------KRTNVSHGLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVVSRDIAKEVY 557
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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