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Conserved domains on  [gi|21436139|gb|AAM51316|]
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putative epoxide hydrolase [Arabidopsis thaliana]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 1-318 6.50e-33

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 121.26  E-value: 6.50e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   1 MEHRNVRGNGIDIHVAIQGPsDGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSDAPAEISSFTcfNIVG 80
Cdd:COG0596   2 STPRFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAAG-YRVIAPDLRGHGRSDKPAGGYTLD--DLAD 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  81 DLVAVISTLikEDKKVFVVGHDWGALIAWYLCLFRPDKVKALVNLSvplsfwptdpsvKPVDRMRAVYGNDYYvcrfqev 160
Cdd:COG0596  78 DLAALLDAL--GLERVVLVGHSMGGMVALELAARHPERVAGLVLVD------------EVLAALAEPLRRPGL------- 136

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139 161 gdieaeiaevgTERVMKRLLTyrtpgpliipkdksfwgskgetiplpsWLTEEDVAyfvskfkekgfcgpvnyyrnfnrn 240
Cdd:COG0596 137 -----------APEALAALLR---------------------------ALARTDLR------------------------ 154

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21436139 241 nELLGpwvgsKIQVPTKFVIGELDLVYYMPgvkeyiHGPQFKEDVPLIEEpVVMEGVAHFLNQEKPQEILQIILDFIS 318
Cdd:COG0596 155 -ERLA-----RITVPTLVIWGEKDPIVPPA------LARRLAELLPNAEL-VVLPGAGHFPPLEQPEAFAAALRDFLA 219
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 1-318 6.50e-33

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 121.26  E-value: 6.50e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   1 MEHRNVRGNGIDIHVAIQGPsDGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSDAPAEISSFTcfNIVG 80
Cdd:COG0596   2 STPRFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAAG-YRVIAPDLRGHGRSDKPAGGYTLD--DLAD 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  81 DLVAVISTLikEDKKVFVVGHDWGALIAWYLCLFRPDKVKALVNLSvplsfwptdpsvKPVDRMRAVYGNDYYvcrfqev 160
Cdd:COG0596  78 DLAALLDAL--GLERVVLVGHSMGGMVALELAARHPERVAGLVLVD------------EVLAALAEPLRRPGL------- 136

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139 161 gdieaeiaevgTERVMKRLLTyrtpgpliipkdksfwgskgetiplpsWLTEEDVAyfvskfkekgfcgpvnyyrnfnrn 240
Cdd:COG0596 137 -----------APEALAALLR---------------------------ALARTDLR------------------------ 154

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21436139 241 nELLGpwvgsKIQVPTKFVIGELDLVYYMPgvkeyiHGPQFKEDVPLIEEpVVMEGVAHFLNQEKPQEILQIILDFIS 318
Cdd:COG0596 155 -ERLA-----RITVPTLVIWGEKDPIVPPA------LARRLAELLPNAEL-VVLPGAGHFPPLEQPEAFAAALRDFLA 219
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 26-135 2.72e-24

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 98.73  E-value: 2.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    26 VLLLHGFPELWYSWRHQISGLAARGYRAVAPDLRGYGDSDAPAEISSFTCFNIVGDLVAVISTLIkeDKKVFVVGHDWGA 105
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILEALG--LEKVNLVGHSMGG 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 21436139   106 LIAWYLCLFRPDKVKALVNLSVPLSFWPTD 135
Cdd:pfam00561  81 LIALAYAAKYPDRVKALVLLGALDPPHELD 110
PRK05855 PRK05855
SDR family oxidoreductase;
1-109 1.30e-21

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 95.05  E-value: 1.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    1 MEHRNVRGNGIDIHVAIQGPSDGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSDAPAEISSFTCFNIVG 80
Cdd:PRK05855   3 PRRTVVSSDGVRLAVYEWGDPDRPTVVLVHGYPDNHEVWDGVAPLLADR-FRVVAYDVRGAGRSSAPKRTAAYTLARLAD 81

                         90       100
                 ....*....|....*....|....*....
gi 21436139   81 DLVAVISTLIKeDKKVFVVGHDWGALIAW 109
Cdd:PRK05855  82 DFAAVIDAVSP-DRPVHLLAHDWGSIQGW 109
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 1-318 6.50e-33

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 121.26  E-value: 6.50e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   1 MEHRNVRGNGIDIHVAIQGPsDGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSDAPAEISSFTcfNIVG 80
Cdd:COG0596   2 STPRFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAAG-YRVIAPDLRGHGRSDKPAGGYTLD--DLAD 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  81 DLVAVISTLikEDKKVFVVGHDWGALIAWYLCLFRPDKVKALVNLSvplsfwptdpsvKPVDRMRAVYGNDYYvcrfqev 160
Cdd:COG0596  78 DLAALLDAL--GLERVVLVGHSMGGMVALELAARHPERVAGLVLVD------------EVLAALAEPLRRPGL------- 136

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139 161 gdieaeiaevgTERVMKRLLTyrtpgpliipkdksfwgskgetiplpsWLTEEDVAyfvskfkekgfcgpvnyyrnfnrn 240
Cdd:COG0596 137 -----------APEALAALLR---------------------------ALARTDLR------------------------ 154

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21436139 241 nELLGpwvgsKIQVPTKFVIGELDLVYYMPgvkeyiHGPQFKEDVPLIEEpVVMEGVAHFLNQEKPQEILQIILDFIS 318
Cdd:COG0596 155 -ERLA-----RITVPTLVIWGEKDPIVPPA------LARRLAELLPNAEL-VVLPGAGHFPPLEQPEAFAAALRDFLA 219
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 26-135 2.72e-24

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 98.73  E-value: 2.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    26 VLLLHGFPELWYSWRHQISGLAARGYRAVAPDLRGYGDSDAPAEISSFTCFNIVGDLVAVISTLIkeDKKVFVVGHDWGA 105
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILEALG--LEKVNLVGHSMGG 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 21436139   106 LIAWYLCLFRPDKVKALVNLSVPLSFWPTD 135
Cdd:pfam00561  81 LIALAYAAKYPDRVKALVLLGALDPPHELD 110
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
9-123 5.11e-22

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 91.99  E-value: 5.11e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   9 NGIDIHVAIQGPSDGT--IVLLLHGFPELWYSWRHQISGLAARGYRAVAPDLRGYGDSDAP-AEISSFTcfNIVGDLVAV 85
Cdd:COG2267  12 DGLRLRGRRWRPAGSPrgTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPrGHVDSFD--DYVDDLRAA 89

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 21436139  86 ISTLIKE-DKKVFVVGHDWGALIAWYLCLFRPDKVKALV 123
Cdd:COG2267  90 LDALRARpGLPVVLLGHSMGGLIALLYAARYPDRVAGLV 128
PRK05855 PRK05855
SDR family oxidoreductase;
1-109 1.30e-21

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 95.05  E-value: 1.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    1 MEHRNVRGNGIDIHVAIQGPSDGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSDAPAEISSFTCFNIVG 80
Cdd:PRK05855   3 PRRTVVSSDGVRLAVYEWGDPDRPTVVLVHGYPDNHEVWDGVAPLLADR-FRVVAYDVRGAGRSSAPKRTAAYTLARLAD 81

                         90       100
                 ....*....|....*....|....*....
gi 21436139   81 DLVAVISTLIKeDKKVFVVGHDWGALIAW 109
Cdd:PRK05855  82 DFAAVIDAVSP-DRPVHLLAHDWGSIQGW 109
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 8-123 1.26e-19

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 87.33  E-value: 1.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    8 GNGIDIHVAIQGPSDGTIVLLLHGFPELWYSWRHQISGLAARGYRAVAPDLRGYGDSDAPAEISSFTCFNIVGDLVAVIS 87
Cdd:PRK00870  31 GGPLRMHYVDEGPADGPPVLLLHGEPSWSYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPTRREDYTYARHVEWMRSWFE 110

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 21436139   88 TLIKEDkkVFVVGHDWGALIAWYLCLFRPDKVKALV 123
Cdd:PRK00870 111 QLDLTD--VTLVCQDWGGLIGLRLAAEHPDRFARLV 144
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 25-141 7.84e-17

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 78.41  E-value: 7.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    25 IVLLLHGFPElwYSWR--HQISGLAARGYRAVAPDLRGYGDSD-APAEISSFTCFniVGDLVAVISTLIKE--DKKVFVV 99
Cdd:pfam12146   6 VVVLVHGLGE--HSGRyaHLADALAAQGFAVYAYDHRGHGRSDgKRGHVPSFDDY--VDDLDTFVDKIREEhpGLPLFLL 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 21436139   100 GHDWGALIAWYLCLFRPDKVKALVnLSVPLsFWPTDPSVKPV 141
Cdd:pfam12146  82 GHSMGGLIAALYALRYPDKVDGLI-LSAPA-LKIKPYLAPPI 121
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
9-126 4.89e-15

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 73.13  E-value: 4.89e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   9 NGIDIHVAIQGPSDGT---IVLLLHGFPE-LWYSWRHQISGLAARGYRAVAPDLRGYGDSDAPAEISSftcfniVGDLVA 84
Cdd:COG1506   6 DGTTLPGWLYLPADGKkypVVVYVHGGPGsRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDE------VDDVLA 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 21436139  85 VISTLIKED----KKVFVVGHDWGALIAWYLCLFRPDKVKALVNLS 126
Cdd:COG1506  80 AIDYLAARPyvdpDRIGIYGHSYGGYMALLAAARHPDRFKAAVALA 125
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 22-123 3.46e-14

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 71.56  E-value: 3.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   22 DGTIVLLLHGFPELWYSWRHQISGLAARGyRAVAPDLRGYGDSDAPAEisSFTCFNIVGDLVAVISTLIKEDkkVFVVGH 101
Cdd:PRK03592  26 EGDPIVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGASDKPDI--DYTFADHARYLDAWFDALGLDD--VVLVGH 100

                         90       100
                 ....*....|....*....|..
gi 21436139  102 DWGALIAWYLCLFRPDKVKALV 123
Cdd:PRK03592 101 DWGSALGFDWAARHPDRVRGIA 122
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
26-131 5.49e-12

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 64.58  E-value: 5.49e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  26 VLLLHGFPELWYSWRHQISGLAARGYRAVAPDLRGYGDSdaPAEISSFTCFNIVGDLVAVISTLIKEDKKVFVVGHDWGA 105
Cdd:COG1647  18 VLLLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTS--PEDLLKTTWEDWLEDVEEAYEILKAGYDKVIVIGLSMGG 95

                        90       100
                ....*....|....*....|....*.
gi 21436139 106 LIAWYLCLFRPDkVKALVNLSVPLSF 131
Cdd:COG1647  96 LLALLLAARYPD-VAGLVLLSPALKI 120
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 26-109 7.57e-12

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 63.65  E-value: 7.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    26 VLLLHGFpelWYSWRHqISGLAARGYRAVAPDLRGYGDSDAPAeissfTCFNIVGDLVAVISTLIkEDKKVFVVGHDWGA 105
Cdd:pfam12697   1 VVLVHGA---GLSAAP-LAALLAAGVAVLAPDLPGHGSSSPPP-----LDLADLADLAALLDELG-AARPVVLVGHSLGG 70


                  ....
gi 21436139   106 LIAW 109
Cdd:pfam12697  71 AVAL 74
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
26-173 1.55e-10

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 59.98  E-value: 1.55e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  26 VLLLHGfpelWYSWRHQISG----LAARGYRAVAPDLRGYGDSDAPAE-----ISSFTCFNIVGDLVAVISTLIKED--- 93
Cdd:COG0412  32 VVVLHE----IFGLNPHIRDvarrLAAAGYVVLAPDLYGRGGPGDDPDearalMGALDPELLAADLRAALDWLKAQPevd 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  94 -KKVFVVGHDWGALIAWYLCLFRPDkVKALVnlsvplSFWPTDPSVKPVDRMRAV-------YG-NDYYVcRFQEVGDIE 164
Cdd:COG0412 108 aGRVGVVGFCFGGGLALLAAARGPD-LAAAV------SFYGGLPADDLLDLAARIkapvlllYGeKDPLV-PPEQVAALE 179


                ....*....
gi 21436139 165 AEIAEVGTE 173
Cdd:COG0412 180 AALAAAGVD 188
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 18-130 1.17e-09

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 58.74  E-value: 1.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   18 QGPSDGTIVLLLHGFPELWYSWRHQISGLaARGYRAVAPDLRGYGDSDAPAEISSF--TCFNIVGDLVAVISTLIKEDKK 95
Cdd:PLN03084 122 SGSNNNPPVLLIHGFPSQAYSYRKVLPVL-SKNYHAIAFDWLGFGFSDKPQPGYGFnyTLDEYVSSLESLIDELKSDKVS 200

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 21436139   96 VFVVGHdWGALIAWYLCLfRPDKVKALVNLSVPLS 130
Cdd:PLN03084 201 LVVQGY-FSPPVVKYASA-HPDKIKKLILLNPPLT 233
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 22-129 4.48e-08

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 53.59  E-value: 4.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   22 DGTIVLLLHGFPELWYSWRHQISGLAARGyRAVAPDLRGYGDSDAP----AEISSFTCFNIVGD-LVAVISTLIKEdkKV 96
Cdd:PLN02824  28 SGPALVLVHGFGGNADHWRKNTPVLAKSH-RVYAIDLLGYGYSDKPnprsAPPNSFYTFETWGEqLNDFCSDVVGD--PA 104

                         90       100       110
                 ....*....|....*....|....*....|...
gi 21436139   97 FVVGHDWGALIAWYLCLFRPDKVKALVNLSVPL 129
Cdd:PLN02824 105 FVICNSVGGVVGLQAAVDAPELVRGVMLINISL 137
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 22-135 5.26e-08

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 53.32  E-value: 5.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   22 DGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSDAPAEISSftcfnIVGDLVAVISTLIKEDK--KVFVV 99
Cdd:PRK03204  33 TGPPILLCHGNPTWSFLYRDIIVALRDR-FRCVAPDYLGFGLSERPSGFGY-----QIDEHARVIGEFVDHLGldRYLSM 106

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 21436139  100 GHDWGALIAWYLCLFRPDKVKALVNLSVplSFWPTD 135
Cdd:PRK03204 107 GQDWGGPISMAVAVERADRVRGVVLGNT--WFWPAD 140
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 26-128 7.36e-08

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 49.83  E-value: 7.36e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  26 VLLLHGFPELWYSWRHQISGLAARGYRAVAPDlrgYGDSDAPAEISsftcfniVGDLVAVISTLIKE--DKKVFVVGHDW 103
Cdd:COG1075   8 VVLVHGLGGSAASWAPLAPRLRAAGYPVYALN---YPSTNGSIEDS-------AEQLAAFVDAVLAAtgAEKVDLVGHSM 77

                        90       100
                ....*....|....*....|....*..
gi 21436139 104 GALIA-WYLC-LFRPDKVKALVNLSVP 128
Cdd:COG1075  78 GGLVArYYLKrLGGAAKVARVVTLGTP 104
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 21-126 1.37e-06

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 49.86  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    21 SDGTIVLLLHGF---PELWYSWRHQISGLAargyRAVAPDLRGYGDSDAPAEIS-SFTCFNIVGDLVA-VISTLIKE--D 93
Cdd:PLN02980 1369 AEGSVVLFLHGFlgtGEDWIPIMKAISGSA----RCISIDLPGHGGSKIQNHAKeTQTEPTLSVELVAdLLYKLIEHitP 1444

                          90       100       110
                  ....*....|....*....|....*....|...
gi 21436139    94 KKVFVVGHDWGALIAWYLCLFRPDKVKALVNLS 126
Cdd:PLN02980 1445 GKVTLVGYSMGARIALYMALRFSDKIEGAVIIS 1477
COG4757 COG4757
Predicted alpha/beta hydrolase [General function prediction only];
46-132 1.12e-05

Predicted alpha/beta hydrolase [General function prediction only];


Pssm-ID: 443790 [Multi-domain]  Cd Length: 289  Bit Score: 46.03  E-value: 1.12e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139  46 LAARGYRAVAPDLRGYGDSdAPAEISSFTcFN----IVGDLVAVISTLIKE--DKKVFVVGHDWGALIAwyLCLFRPDKV 119
Cdd:COG4757  55 LAERGFAVLTYDYRGIGLS-RPGSLRGFD-AGyrdwGELDLPAVLDALRARfpGLPLLLVGHSLGGQLL--GLAPNAERV 130

                        90
                ....*....|...
gi 21436139 120 KALVNLSVPLSFW 132
Cdd:COG4757 131 DRLVTVASGSGYW 143
PLN02578 PLN02578
hydrolase
 13-125 1.69e-05

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 45.99  E-value: 1.69e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   13 IHVAIQGpsDGTIVLLLHGFPELWYSWRHQISGLAARgYRAVAPDLRGYGDSD-APAEISSFTCFNIVGDLVAVIstlIK 91
Cdd:PLN02578  78 IHYVVQG--EGLPIVLIHGFGASAFHWRYNIPELAKK-YKVYALDLLGFGWSDkALIEYDAMVWRDQVADFVKEV---VK 151

                         90       100       110
                 ....*....|....*....|....*....|....
gi 21436139   92 EdkKVFVVGHDWGALIAWYLCLFRPDKVKALVNL 125
Cdd:PLN02578 152 E--PAVLVGNSLGGFTALSTAVGYPELVAGVALL 183
PLN03087 PLN03087
BODYGUARD 1 domain containing hydrolase; Provisional
 15-147 6.81e-05

BODYGUARD 1 domain containing hydrolase; Provisional


Pssm-ID: 215567  Cd Length: 481  Bit Score: 44.41  E-value: 6.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   15 VAIQGPSDGTI---VLLLHGFPELWYSWRHQI----SGLAARGYRAVAPDLRGYGDSDAPAEiSSFTcfniVGDLVAVI- 86
Cdd:PLN03087 190 VHVQQPKDNKAkedVLFIHGFISSSAFWTETLfpnfSDAAKSTYRLFAVDLLGFGRSPKPAD-SLYT----LREHLEMIe 264

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21436139   87 -STLIKEDKKVF-VVGHDWGALIAWYLCLFRPDKVKALVNLSVPlsFWPTDPSVKPVDR-MRAV 147
Cdd:PLN03087 265 rSVLERYKVKSFhIVAHSLGCILALALAVKHPGAVKSLTLLAPP--YYPVPKGVQATQYvMRKV 326
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 1-132 1.43e-04

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 42.59  E-value: 1.43e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   1 MEHRNVR---GNGIDIHVAIQGPSDGT----IVLLLHGFPELWYSWRHQISGLAARGYRAVAPDLRGYGDSD-APAEISS 72
Cdd:COG1073   8 VNKEDVTfksRDGIKLAGDLYLPAGASkkypAVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGYGESEgEPREEGS 87

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21436139  73 FTCFnivgDLVAVISTLIK----EDKKVFVVGHDWGALIAWYLCLFRPDkVKALVNLSVPLSFW 132
Cdd:COG1073  88 PERR----DARAAVDYLRTlpgvDPERIGLLGISLGGGYALNAAATDPR-VKAVILDSPFTSLE 146
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
8-129 2.36e-04

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 42.44  E-value: 2.36e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139   8 GNGIDIHVAIQGPSDGTIVLLLHGfpelwysW-----RHQISGLA----ARGYRAVAPDLRGYGDSDAPAEI---SSFTc 75
Cdd:COG0429  46 GDFVDLDWSDPPAPSKPLVVLLHG-------LegssdSHYARGLAralyARGWDVVRLNFRGCGGEPNLLPRlyhSGDT- 117

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 21436139  76 fnivGDLVAVISTLIKE--DKKVFVVGHDWGA-LIAWYLCL--FRPDKVKALVNLSVPL 129
Cdd:COG0429 118 ----EDLVWVLAHLRARypYAPLYAVGFSLGGnLLLKYLGEqgDDAPPLKAAVAVSPPL 172
DLH pfam01738
Dienelactone hydrolase family;
46-137 8.60e-03

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 36.95  E-value: 8.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21436139    46 LAARGYRAVAPDL-RGYGDSDAPAEI--------SSFTCFNIVGDLVAVISTL----IKEDKKVFVVGHDWGALIAWYLC 112
Cdd:pfam01738  35 LADEGYVALAPDLyFRQGDPNDEADAaramfelvSKRVMEKVLDDLEAAVNYLksqpEVSPKKVGVVGYCMGGALAVLLA 114

                          90       100
                  ....*....|....*....|....*
gi 21436139   113 LfRPDKVKALVnlsvplSFWPTDPS 137
Cdd:pfam01738 115 A-KGPLVDAAV------GFYGVGPE 132
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 13-71 9.47e-03

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 37.51  E-value: 9.47e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 21436139   13 IHVAIQGPSDGTIVLLLHGFPELWYSWRHQISGLAaRGYRAVAPDLRGYGDSDAPAEIS 71
Cdd:PLN02679  78 VKGSPEVTSSGPPVLLVHGFGASIPHWRRNIGVLA-KNYTVYAIDLLGFGASDKPPGFS 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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