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Conserved domains on  [gi|21429170|gb|AAM50304|]
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RE56970p [Drosophila melanogaster]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 70-339 2.02e-37

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 136.44  E-value: 2.02e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   70 VAGGIAGAVSRTCTAPLDRIKVYLQVQ----------TQRM-GISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFA 138
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTQdsipeiksgkVPRYsGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  139 AYEQMKRLIRGDDgsrQMSIVERFYA-----GAAAGGISQTIIYPMEVLKTRLA--LRRTG--QYAGIADAAVKIYKQEG 209
Cdd:PTZ00169  92 FKDYFKNMFPKYN---QKTDFWKFFGvnilsGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLMKISKQTG 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  210 VRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIAnhdNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQaqaaeT 289
Cdd:PTZ00169 169 FLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFG---NDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMM-----M 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 21429170  290 IANQKRKTQIPLKSSdahsgeetmTGLFRKIVRQEGLTGLYRGITPNFLK 339
Cdd:PTZ00169 241 MSGRKAKSEIQYTGT---------LDCWKKILKNEGLGGFFKGAWANVLR 281
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 70-339 2.02e-37

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 136.44  E-value: 2.02e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   70 VAGGIAGAVSRTCTAPLDRIKVYLQVQ----------TQRM-GISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFA 138
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTQdsipeiksgkVPRYsGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  139 AYEQMKRLIRGDDgsrQMSIVERFYA-----GAAAGGISQTIIYPMEVLKTRLA--LRRTG--QYAGIADAAVKIYKQEG 209
Cdd:PTZ00169  92 FKDYFKNMFPKYN---QKTDFWKFFGvnilsGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLMKISKQTG 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  210 VRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIAnhdNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQaqaaeT 289
Cdd:PTZ00169 169 FLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFG---NDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMM-----M 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 21429170  290 IANQKRKTQIPLKSSdahsgeetmTGLFRKIVRQEGLTGLYRGITPNFLK 339
Cdd:PTZ00169 241 MSGRKAKSEIQYTGT---------LDCWKKILKNEGLGGFFKGAWANVLR 281
Mito_carr pfam00153
Mitochondrial carrier protein;
155-243 2.70e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 105.82  E-value: 2.70e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   155 QMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRT---GQYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGID 231
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81

                          90
                  ....*....|..
gi 21429170   232 LAVYETLKRRYI 243
Cdd:pfam00153  82 FGTYETLKRLLL 93
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 70-339 2.02e-37

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 136.44  E-value: 2.02e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   70 VAGGIAGAVSRTCTAPLDRIKVYLQVQ----------TQRM-GISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFA 138
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTQdsipeiksgkVPRYsGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  139 AYEQMKRLIRGDDgsrQMSIVERFYA-----GAAAGGISQTIIYPMEVLKTRLA--LRRTG--QYAGIADAAVKIYKQEG 209
Cdd:PTZ00169  92 FKDYFKNMFPKYN---QKTDFWKFFGvnilsGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLMKISKQTG 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  210 VRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIAnhdNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQaqaaeT 289
Cdd:PTZ00169 169 FLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFG---NDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMM-----M 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 21429170  290 IANQKRKTQIPLKSSdahsgeetmTGLFRKIVRQEGLTGLYRGITPNFLK 339
Cdd:PTZ00169 241 MSGRKAKSEIQYTGT---------LDCWKKILKNEGLGGFFKGAWANVLR 281
Mito_carr pfam00153
Mitochondrial carrier protein;
155-243 2.70e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 105.82  E-value: 2.70e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   155 QMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRT---GQYAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGID 231
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81

                          90
                  ....*....|..
gi 21429170   232 LAVYETLKRRYI 243
Cdd:pfam00153  82 FGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
65-150 1.87e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.80  E-value: 1.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170    65 WWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQ-----TQRMGISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAA 139
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84

                          90
                  ....*....|.
gi 21429170   140 YEQMKRLIRGD 150
Cdd:pfam00153  85 YETLKRLLLKK 95
Mito_carr pfam00153
Mitochondrial carrier protein;
250-361 2.01e-20

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 84.63  E-value: 2.01e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   250 EQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQaaetianqkrktqiplkSSDAHSGEETMTGLFRKIVRQEGLTGL 329
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----------------GGSGKSKGRGILDCFKKIYKEEGIRGL 63

                          90       100       110
                  ....*....|....*....|....*....|..
gi 21429170   330 YRGITPNFLKVLPAVSISYVVYEYTSRALGIK 361
Cdd:pfam00153  64 YKGLLPNLLRVAPAAAIYFGTYETLKRLLLKK 95
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 152-332 5.28e-12

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 65.95  E-value: 5.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  152 GSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRT------GQ---YAGIADAAVKIYKQEGVRSFYRGYVPNIL 222
Cdd:PTZ00169   1 MDKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSipeiksGKvprYSGIVNCFRRVSKEQGVLSLWRGNTANVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  223 GILPYAGIDLAVYETLKR---RYiaNHDNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLqaqAAETIANQKRKtqi 299
Cdd:PTZ00169  81 RYFPTQAFNFAFKDYFKNmfpKY--NQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRL---ASDIGKGGDRE--- 152

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 21429170  300 plkssdahsgeetMTGLF---RKIVRQEGLTGLYRG 332
Cdd:PTZ00169 153 -------------FTGLFdclMKISKQTGFLSLYQG 175
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 35-222 7.68e-11

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 62.48  E-value: 7.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   35 FRDMMGRYldigedmNVPDDFTQkemqtgLWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQV------QTQRMGISECMHI 108
Cdd:PTZ00169  96 FKNMFPKY-------NQKTDFWK------FFGVNILSGGLAGASSLLIVYPLDFARTRLASdigkggDREFTGLFDCLMK 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  109 MLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLIRGDDGSRQMsiverFYAGAAAGGISQT---IIYPMEVLKTR 185
Cdd:PTZ00169 163 ISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNI-----LYKWAVAQTVTILaglISYPFDTVRRR 237

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 21429170  186 LAL---RRTG---QYAGIADAAVKIYKQEGVRSFYRGYVPNIL 222
Cdd:PTZ00169 238 MMMmsgRKAKseiQYTGTLDCWKKILKNEGLGGFFKGAWANVL 280
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 67-281 2.89e-05

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 44.92  E-value: 2.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   67 RHLVAGGIAGAVSRTCTAPLDRIKVYLQVQtQRMGISEcmhimlneggSRSMWRGNGINVLKIAPETAFKFAAYEQMKRL 146
Cdd:PTZ00168   5 HNLVTGALSGVIVDAVLYPIDSIKTNIQAK-KSFSFSD----------IKKLYSGILPTLVGTVPASAFFYCFYELSKKL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  147 IRgdDGSRQMSIVERFYAGAAAGGISQTII-YPMEVLKTRLalrrtgQYAGIADAAVKIY---KQEGVRSFY-RGYVPNI 221
Cdd:PTZ00168  74 LT--EYRENISKTNLYLISTSIAEITACIVrLPFEIVKQNM------QVSGNISVLKTIYeitQREGLPSFLgKSYFVMI 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21429170  222 LGILPYAGIDLAVYETLKRRYIANHDNNEQ--PSFLVLLaCGSTSSTLGQLCSYPLALVRTR 281
Cdd:PTZ00168 146 VREIPFDCIQYFLWETLKEKAKKDFGKFSKkyPSITSAI-CGGLAGGIAGFLTTPVDVIKSR 206
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 156-292 2.73e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 39.14  E-value: 2.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170  156 MSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTGQYAGIadaavkiykqegvRSFYRGYVPNILGILPYAGIDLAVY 235
Cdd:PTZ00168   1 MEHFHNLVTGALSGVIVDAVLYPIDSIKTNIQAKKSFSFSDI-------------KKLYSGILPTLVGTVPASAFFYCFY 67

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 21429170  236 EtLKRRYIANHDNNEQPSFLVLLACgSTSSTLGQLCSYPLALVRTRLQAQAAETIAN 292
Cdd:PTZ00168  68 E-LSKKLLTEYRENISKTNLYLIST-SIAEITACIVRLPFEIVKQNMQVSGNISVLK 122
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 68-216 7.69e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 37.60  E-value: 7.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21429170   68 HLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMGISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLI 147
Cdd:PTZ00168  87 YLISTSIAEITACIVRLPFEIVKQNMQVSGNISVLKTIYEITQREGLPSFLGKSYFVMIVREIPFDCIQYFLWETLKEKA 166

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21429170  148 RGDDG--SRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRTGQYAGIADAAvkiykQEGVRSFYRG 216
Cdd:PTZ00168 167 KKDFGkfSKKYPSITSAICGGLAGGIAGFLTTPVDVIKSRQIIYGKSYIETVTEIA-----EEGYLTFYKG 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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