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Conserved domains on  [gi|20377177|gb|AAM20786|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Ectodus descampsii]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 559.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPILT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  241 ALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSAQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 20377177  321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 559.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPILT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  241 ALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSAQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 20377177  321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 2.24e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 86.98  E-value: 2.24e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    23 SSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQIQPSN---STLLIILGLTSTLV 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFVMTFSTFLVFKL-----NKATNINTLATSWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 20377177   235 KAPILTALAPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-299 1.31e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 77.46  E-value: 1.31e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   9 LLFGLgLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQaaaaatllfaSVTNAWL------- 80
Cdd:COG1007 108 LLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLG----------ALSSGFLlygisll 176

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  81 ---TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQI 145
Cdd:COG1007 177 ygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRL 256

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177 146 --------QPSNSTLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFVMTFS 213
Cdd:COG1007 257 lveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLG 336

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177 214 TFLVF-----KLNKATNINTLATSWTKAPILTALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLS 288
Cdd:COG1007 337 AFAVIlllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVIS 416

                       330
                ....*....|.
gi 20377177 289 LYFYLRLSYAM 299
Cdd:COG1007 417 AYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 98-299 1.43e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 71.13  E-value: 1.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPS--------NSTLLIILGLTSTLVGGWGGL 169
Cdd:TIGR01770 209 ILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYilfgfseaWQIFLAIIAFLSMLIGNFGAL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   170 NQTQLRKILAYSSIAHLGWMILVLQFSPSI----TLLTLLTYFVMTFSTFLVF------KLNKATNINTLATSWTKAPIL 239
Cdd:TIGR01770 289 AQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLsllrsyKDEWIEYISDFAGLFKTNPIL 368

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:TIGR01770 369 AILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 559.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPILT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  241 ALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSAQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 20377177  321 LTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 5.01e-133

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 383.12  E-value: 5.01e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPS-NSTLLIILGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPIL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLpSA 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*..
gi 20377177  320 QLTYPLATSTAMTICLLPLTPAISALL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.11e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 337.95  E-value: 2.11e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPS-NSTLLIILGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPIL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSA 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 20377177  320 QLTYpLATSTAMTICLLPLTPAISALL 346
Cdd:MTH00112 321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 4.95e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 329.50  E-value: 4.95e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPS-NSTLLIILGLT 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPIL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSA 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*.
gi 20377177  320 QLTYPLATSTAMTICLLPLTPAISAL 345
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 4.40e-102

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 304.20  E-value: 4.40e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPS-NSTLLIILGLT 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPAlNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPIL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSa 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKS- 319

                        330       340
                 ....*....|....*....|....*...
gi 20377177  320 QLTYPLATSTAMTICLLPLTPAISALLT 347
Cdd:MTH00200 320 NSNLLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 4.92e-75

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 235.21  E-value: 4.92e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    1 MNPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWL 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-QPSNSTLLIILGLT 159
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPIL 239
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSA 319
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|.
gi 20377177  320 QLTYPLATSTAMTICLLPLTP 340
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLL 341
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 10-307 9.05e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 169.23  E-value: 9.05e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   10 LFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGqweiqqI 89
Cdd:MTH00160  11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM------L 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   90 THPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLIILglTSTLVGGWGGL 169
Cdd:MTH00160  85 FNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIII--LSAIIGAIGGL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  170 NQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPILTALAPLILLS 249
Cdd:MTH00160 163 NQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLS 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 20377177  250 LGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNN 307
Cdd:MTH00160 243 LGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-318 1.51e-41

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 147.73  E-value: 1.51e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   10 LFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIqqi 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   90 thplpSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNS--TLLIILGLTSTLVGGWG 167
Cdd:MTH00144  87 -----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMtfSTFLVFKLNKATNINTLATSWTKAPILTALAPLIL 247
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVS--SGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISL 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20377177  248 LSLGG-LPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPS 318
Cdd:MTH00144 240 LLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSS 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 15-329 4.73e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 141.07  E-value: 4.73e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASvtnawlTGQWEIQQITHPLP 94
Cdd:MTH00011  17 LGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKNIT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   95 STMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLII-LGLTSTLVGGWGGLNQTQ 173
Cdd:MTH00011  91 ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMNQTQ 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  174 LRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPILTALAPLILLSLGGL 253
Cdd:MTH00011 171 LRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGL 250

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 20377177  254 PPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTlTISPNNLTGTTPWRLPSAQLTYPLATST 329
Cdd:MTH00011 251 PPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM-YLSPTFSSLKSAPYEPKTKILISMCTLS 325
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-297 4.09e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 138.27  E-value: 4.09e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    9 LLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLlfasvtnawLTGQWEIQQ 88
Cdd:MTH00197   3 FLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALL---------LMGGSLSFS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   89 --ITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFaLILQIQPSNSTLLIILGLTSTLVGGW 166
Cdd:MTH00197  74 nlYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL-LILAFNSSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  167 GGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFSTFLVFKLNKATNINTLATSWTKAPILTALAPLI 246
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 20377177  247 LLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSY 297
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-266 1.71e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 93.94  E-value: 1.71e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHP-RAVEATTKYFLTQAAA-------------AATLLFASVTNAWL 80
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSsglflfgcallcgTTGGLHLSYINLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPsNSTLLIILGLTS 160
Cdd:MTH00196  84 NSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL-NVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYFVMT---FSTFLVFKLNKATNINTLATSw 233
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSicvFSIILALNVYKNLIIEFSGLS- 241

                        250       260       270
                 ....*....|....*....|....*....|...
gi 20377177  234 TKAPILTALAPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00196 242 RRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 2.24e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 86.98  E-value: 2.24e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    23 SSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQIQPSN---STLLIILGLTSTLV 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFVMTFSTFLVFKL-----NKATNINTLATSWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 20377177   235 KAPILTALAPLILLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-266 2.35e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 88.54  E-value: 2.35e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   13 LGLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLTGQWEIQQITH 91
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   92 PLPS----TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLIILGLtSTLVGGWG 167
Cdd:MTH00199 186 ILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVL-SIIYGAIG 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  168 GLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYFVMT---FSTFLVFKLNKATNINTLATSwTKAPILT 240
Cdd:MTH00199 265 ALNQTKIKRLLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSicsFSIILSLKLTKGLIVEVSGLS-RKNPVIA 343

                        250       260
                 ....*....|....*....|....*.
gi 20377177  241 ALAPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00199 344 LTLALTFLSIAGIPPLAGFLSKWLIL 369
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-299 1.31e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 77.46  E-value: 1.31e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   9 LLFGLgLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHHHPRAVEATTKYFLTQaaaaatllfaSVTNAWL------- 80
Cdd:COG1007 108 LLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLG----------ALSSGFLlygisll 176

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  81 ---TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQI 145
Cdd:COG1007 177 ygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRL 256

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177 146 --------QPSNSTLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFVMTFS 213
Cdd:COG1007 257 lveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLG 336

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177 214 TFLVF-----KLNKATNINTLATSWTKAPILTALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLS 288
Cdd:COG1007 337 AFAVIlllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVIS 416

                       330
                ....*....|.
gi 20377177 289 LYFYLRLSYAM 299
Cdd:COG1007 417 AYYYLRVVKAM 427
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
97-299 2.79e-15

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 76.40  E-value: 2.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQI--------QPSNSTLLIILGLTSTLVGGWGG 168
Cdd:PRK05777 209 FLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafgglSEDWQQVLAIIAIASMLVGNLAA 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  169 LNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFVMTFSTFLVFKLNK-----ATNINTLATSWTKAPIL 239
Cdd:PRK05777 289 LSQTNIKRLLAYSSIAHAGYLLVGLaagtAEGYSAVLFYLLAYLFMTLGAFGVISLLRrkggeAESISDFAGLSKRSPLL 368

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:PRK05777 369 AAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIKLM 428
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 98-299 1.43e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 71.13  E-value: 1.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPS--------NSTLLIILGLTSTLVGGWGGL 169
Cdd:TIGR01770 209 ILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYilfgfseaWQIFLAIIAFLSMLIGNFGAL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   170 NQTQLRKILAYSSIAHLGWMILVLQFSPSI----TLLTLLTYFVMTFSTFLVF------KLNKATNINTLATSWTKAPIL 239
Cdd:TIGR01770 289 AQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLsllrsyKDEWIEYISDFAGLFKTNPIL 368

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   240 TALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:TIGR01770 369 AILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 2.18e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 58.42  E-value: 2.18e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 20377177   290 YFYLRLSYAMTLTISPNNLTGTTPWRLPSAQLTYPLATSTAMTICLLPLTP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 5-237 2.97e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.49  E-value: 2.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177    5 GLATLLFgLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAV---------EATTKYFLTQAAAAATLLFASV 75
Cdd:MTH00198 190 GFALVLI-VGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCA 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   76 TNAWLTGQ--------------WEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFAL 141
Cdd:MTH00198 269 LYFGFTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYIL 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  142 ILQIQPSnSTLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVmtfsTFLVFKLN 221
Cdd:MTH00198 349 LTSLVIT-SKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV----TYLVSALA 423

                        250
                 ....*....|....*.
gi 20377177  222 KATNINTLATSWTKAP 237
Cdd:MTH00198 424 SFTVICTLEEFGTRTP 439
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-273 1.56e-09

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 59.01  E-value: 1.56e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   2 NPYGLATLLFGLGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHHHPRAVEATTKYFLTQAAAAATLLFASVTNAWLT 81
Cdd:COG0651 105 RGRRFYPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGAT 184

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  82 GQWEIQQITHPLPS----------TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGL--ILSTWQKLAP 138
Cdd:COG0651 185 GTLNMADLAARLAEldpglllaafALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFG 264

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177 139 FALILQIQPsnstLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMT------- 211
Cdd:COG0651 265 ADPALFLGT----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHalakall 340

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 20377177 212 -FSTFLVFKLNKATNINTLATSWTKAPILTALAPLILLSLGGLPPLTGFMPKWLILQELTKQG 273
Cdd:COG0651 341 fLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAG 403
ndhB CHL00049
NADH dehydrogenase subunit 2
 98-336 2.05e-08

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 55.40  E-value: 2.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQ----PSNST----LLIILGLTSTLVGGWGGL 169
Cdd:CHL00049 220 ITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSNewhlLLEILAILSMILGNLIAI 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  170 NQTQLRKILAYSSIAHLGW-MILVLQFSPSITLLTLLTYFVM-------TFSTFLVFKLNKAT-NINTLATSWTKAPILT 240
Cdd:CHL00049 300 TQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFyifmnlgTFACIVLFGLRTGTdNIRDYAGLYTKDPFLA 379

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  241 ALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGTTPWRLPSaq 320
Cdd:CHL00049 380 LSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIIKLLMTGRNQEITPYVRNYRRSP-- 457

                        250
                 ....*....|....*.
gi 20377177  321 LTYPLATSTAMTICLL 336
Cdd:CHL00049 458 LRSNNSIELSMIVCVI 473
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 100-191 5.11e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 54.18  E-value: 5.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   100 LALALKIGLAPLHAWLPEV-LQGLDLTTGLILSTWQKLAPFALI---LQIQPSNS----TLLIILGLTSTLVGGWGGLNQ 171
Cdd:TIGR01972 211 IAFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLrfnLPLFPDASlyfaPVLAALGVIAIIYGALIALAQ 290

                          90       100
                  ....*....|....*....|
gi 20377177   172 TQLRKILAYSSIAHLGWMIL 191
Cdd:TIGR01972 291 TDIKRLIAYSSISHMGFVLL 310
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-271 2.37e-06

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 48.33  E-value: 2.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNSTLLIILGLTSTLVGGWgglNQTQLRK 176
Cdd:MTH00091  62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMF---LLKSYKN 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  177 ILAYSSIAHLGWMILVLQFSPSITLLTLLTYFVMTFstFLVFKLNKATNINTLatSWTKAPILTALAPLIllslgglppl 256
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLML--FLIPKFNNVNKLNFV--SWETLLVFMNLPFSV---------- 204

                        170
                 ....*....|....*
gi 20377177  257 tGFMPKWLILQELTK 271
Cdd:MTH00091 205 -TFFVKIFSLSEILK 218
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 100-191 6.45e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 47.77  E-value: 6.45e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177 100 LALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFALI---LQIQP----SNSTLLIILGLTSTLVGGWG 167
Cdd:COG1008 217 IAFAVKVPMFPFHTWLPDAHVeaptaGSVLLAGVLL----KMGGYGLLrfaLPLFPeasaYFAPLLAALGVIGIIYGALV 292

                        90       100
                ....*....|....*....|....
gi 20377177 168 GLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:COG1008 293 ALAQTDLKRLIAYSSVSHMGFVLL 316
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 78-193 7.86e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 47.45  E-value: 7.86e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  78 AWLTGQWEIQQI----THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQG-----------LDLTTGLILstwqk 135
Cdd:COG1009 186 GAIAGTLNFSELlaaaPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDAMEGptpvsallhaaTMVKAGVYL----- 260

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 20377177 136 LAPFALILQIQPSNSTLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:COG1009 261 LARLSPLFALSPVWLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-335 1.00e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.18  E-value: 1.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI----------LQIQPSNSTLLIILGLTSTLVGG 165
Cdd:PRK08375 207 FVLLALALKAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGS 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFS----PSITLLTLLTYFVMTFSTFL----VFKLNKATNINTLATSWTKAP 237
Cdd:PRK08375 287 LAALGQDDVKRVLAYSTVSQMGYILLGLALLtplaLAAGLLHLLHHALMKGALFLaagaIEVTYGTRRLSELSGLGRRMP 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  238 ILTALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYAMTLTISPNNltGTTPWRLP 317
Cdd:PRK08375 367 LTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPPG--SEAPKQEA 444

                        250
                 ....*....|....*...
gi 20377177  318 SAQLTYPLATSTAMTICL 335
Cdd:PRK08375 445 PLGMLAPSLALALLSLLL 462
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 85-193 2.30e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 46.08  E-value: 2.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   85 EIQQITHPLPSTMITLALAL-------KIGLAPLHAWLPE-----------VLQGLDLTTGLILSTWQKLAPFALILQIQ 146
Cdd:PRK06458 200 ELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYILIDAAIGSDF 279

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 20377177  147 PSNstLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK06458 280 PGR--LLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFAL 324
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 92-299 2.34e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 46.12  E-value: 2.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   92 PLPSTMITLALAL-----KIGLAPLHAWLPEV-----------LQGLDLTTG---------LILSTWQKLAPFALILQIq 146
Cdd:PRK12667 218 PPLALGVALALALwaftiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALSP- 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  147 psnstLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFV-------MTFSTFLVF- 218
Cdd:PRK12667 297 -----ILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksLLFLASGVFi 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  219 KLNKATNINTLATSWTKAPILTALAPLILLSLGGLPPLTGFMPKWLILQELTKQGLAPTATLAALSALLSLYFYLRLSYA 298
Cdd:PRK12667 372 HAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451


                 .
gi 20377177  299 M 299
Cdd:PRK12667 452 L 452
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-193 5.36e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 44.91  E-value: 5.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   81 TGQWEIQQI-THPLPSTMITLALAL-------KIGLAPLHAWLPE-----------------VLQGLDLTTglilstwqK 135
Cdd:PRK12644 184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYLVA--------R 255

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 20377177  136 LAP-FALILQIQPsnstLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK12644 256 LAPgFADVPVWRP----TVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
102-262 5.85e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 44.66  E-value: 5.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  102 LALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQ----PSNST----LLIILGLTSTLVGGWGGLNQTQ 173
Cdd:PRK02504 220 IAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLvtafPSFDEqwklLFTALAILSMVLGNVVALAQTS 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  174 LRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFVMT---FSTFLVFKLNKATN-INTLATSWTKAPILTALAPL 245
Cdd:PRK02504 300 MKRMLAYSSIGQAGFVMIGLvagtEAGYASMVFYLLAYLFMNlgaFACVILFSLRTGTDqISDYAGLYQKDPLLTLGLSL 379

                        170
                 ....*....|....*..
gi 20377177  246 ILLSLGGLPPLTGFMPK 262
Cdd:PRK02504 380 CLLSLGGIPPLAGFFGK 396
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 75-191 8.03e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 44.42  E-value: 8.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   75 VTNAWLTGQWEIQQI-THPLPSTMITL-------ALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFAL 141
Cdd:PRK05846 186 VVYYNATGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPDAHVqaptaGSVLLAGILL----KMGAYGL 261

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 20377177  142 I---LQIQPSNS----TLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK05846 262 LrfsLPLFPDAShefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTL 318
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
96-202 8.42e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 44.32  E-value: 8.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQIQPSNSTL----LIILGLTSTLVGGWG 167
Cdd:PRK07363 209 TGLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGgVLAKLGTYGLLrfgLQLFPQTWSLvapgLAIIGTISVIYGALS 288

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 20377177  168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLL 202
Cdd:PRK07363 289 AIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 96-224 5.30e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.66  E-value: 5.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   96 TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGLilstWQKLAPFALILQIQ--PSNSTLLIILGLTSTL 162
Cdd:PRK08676 210 LFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQSGaaEQFSNVLIGLGIFSIA 285

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20377177  163 VGGWGGLNQTQLRKILAYSSIAHLGWMILvlqfspSITLLTLLTYFVMTFSTfLVFKLNKAT 224
Cdd:PRK08676 286 VAAFSMLSQRNLKKLIAFSSIEHMGLMLL------GIGIGTPLALFWMLFHM-LAHSLVKSG 340
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-207 6.67e-04

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 41.60  E-value: 6.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  111 LHAWLPEVLQGLDLTTGLI-LSTWQKLAPFALI-----LQIQPSNSTLLIILGLTSTLVGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrssplFEQAPLALIIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                         90       100
                 ....*....|....*....|....
gi 20377177  185 HLGWMILVLQFSP-SITLLTLLTY 207
Cdd:MTH00020 309 QLGYMVVACGLSHySISLFHLMNH 332
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 100-191 7.10e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.17  E-value: 7.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  100 LALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQIQPSN----STLLIILGLTSTLVGGWGGLNQ 171
Cdd:PRK12561 193 IAFGVKLPIFPLHTWLPDAHGEASAPVSMILAgVLLKMGGYALIrfnVQMLPDAhvyfAPALAILGVVNIIYGALNAFAQ 272

                         90       100
                 ....*....|....*....|
gi 20377177  172 TQLRKILAYSSIAHLGWMIL 191
Cdd:PRK12561 273 DNVKRRLAYSSVSHMGFVLL 292
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-193 9.44e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 41.06  E-value: 9.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   98 ITLALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFAL------ILQIQPSN-STLLIILGLTSTLVGG 165
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLvrlswpILPLGAQNlAPAVIAMGIVGIVYGS 311

                         90       100
                 ....*....|....*....|....*...
gi 20377177  166 WGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:MTH00226 312 FATCRQIDVKRLVAYSSVAHMGLVSITL 339
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
98-191 1.21e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.45  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   98 ITLALALKIGLAPLHAWLPE-----------VLQG--LDLTT--------GLILSTWQKLAPFalilqiqpsnstlLIIL 156
Cdd:PRK06473 211 ILVGFGIKIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPW-------------LATW 277

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 20377177  157 GLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK06473 278 AVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILL 312
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 1.30e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 40.71  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  111 LHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQP----SNSTLLII--LGLTSTLVGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekAPLTLLIItiFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 20377177  185 HLGWMILVL 193
Cdd:MTH00032 324 QLGYMVLII 332
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 98-266 1.30e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 40.49  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI-----------LQIQPSNSTLLIILGLTSTLVGG 165
Cdd:PRK12662 215 IMVGLFIKAALFPFHKWLIQAYSEAPSFISVFFSgTSTKVMIYLIIrivydvfkanfVFTTLPFNNVFMILAALAIVFGS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFV----MTFSTFLV-----FKLNKaTNINTLATSWTKA 236
Cdd:PRK12662 295 VLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVnhsiVKSALFMVsgsisYHFGT-TKLEDCLNLWKSM 373

                        170       180       190
                 ....*....|....*....|....*....|
gi 20377177  237 PILTALAPLILLSLGGLPPLTGFMPKWLIL 266
Cdd:PRK12662 374 PKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-191 1.86e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 40.01  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  110 PLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQPSNS------TLLIILGLTSTLVGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK07376 245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPVFEqfpavmTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324


                 ....*...
gi 20377177  184 AHLGWMIL 191
Cdd:PRK07376 325 SQLGYMVM 332
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-200 2.05e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 39.65  E-value: 2.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  100 LALALKIGLAPLHAWLPE-----------VLQGLDLTTG---LILSTWQKL-------APFALILqiqpsnSTLLIILGL 158
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQahveapvagsvILAGVLLKLGgygFIRFSWPLLpeaseyfSPLIQTL------SLLAIIYGS 287

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 20377177  159 TSTLvggwgglNQTQLRKILAYSSIAHLGWMILVLqFSPSIT 200
Cdd:MTH00217 288 LTTC-------RQVDLKRIIAYSSVAHMGLVTLGI-FSHTIQ 321
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 96-193 2.05e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 39.75  E-value: 2.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTW-QKLAPFAL-----ILQIQPSNST---LLIILGLTSTLVGGW 166
Cdd:PRK08377 210 ALLIFGLAVEAELFPLNAWAPDAYQAAPHPITVMFSAFvVKAGLYAMarilyLMQNANGWSSvlkLVIIMATLTVFFAEL 289

                         90       100
                 ....*....|....*....|....*..
gi 20377177  167 GGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK08377 290 SALRQKNVKRMIAYSSIGQVGMIALAL 316
PRK12650 PRK12650
DUF4040 family protein;
110-190 2.35e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 40.03  E-value: 2.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  110 PLHAWLPEVLQGLD-----------LTTGLILstwqkLAPFALILQIQPSNSTLLIILGLTSTLVGGWGGLNQTQLRKIL 178
Cdd:PRK12650 226 PFHFWLPEAMAAITpvsaflhaaavVKAGIYL-----LLRFSPVFHDVAVWNWLLIIVGMITALMGAVFAVQKTDLKKLT 300

                         90
                 ....*....|..
gi 20377177  179 AYSSIAHLGWMI 190
Cdd:PRK12650 301 AYSTVSQLGWIV 312
ND5 MTH00066
NADH dehydrogenase subunit 5; Provisional
 78-189 3.11e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214416 [Multi-domain]  Cd Length: 598  Bit Score: 39.51  E-value: 3.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   78 AWL---TGQWEIQQITHPLPSTMITL-----ALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQIQP-- 147
Cdd:MTH00066 185 AWLamnTNSWELQQIFLLNDNSTLPLlglilAAAGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRFHPll 264

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 20377177  148 -SNSTLLII---LGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWM 189
Cdd:MTH00066 265 eNNQTALTIclcLGALTTLFTAACALTQNDIKKIVAFSTSSQLGLM 310
PRK12668 PRK12668
Na(+)/H(+) antiporter subunit D;
88-190 6.48e-03

Na(+)/H(+) antiporter subunit D;


Pssm-ID: 237168 [Multi-domain]  Cd Length: 581  Bit Score: 38.34  E-value: 6.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   88 QITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTW-QKLAPFALILQIqPSNStLLIILGLTSTLVGGW 166
Cdd:PRK12668 179 AGLGGTAAWLILIGFGVNAAFPPLHAWLPDAYPEATVTGSVFLSAFtTKTAVYALARAF-PGTE-LLIYIGAAMAVYGVF 256

                         90       100
                 ....*....|....*....|....
gi 20377177  167 GGLNQTQLRKILAYSSIAHLGWMI 190
Cdd:PRK12668 257 FALLENDLRRLLSYHIVSQVGYMV 280
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-203 7.20e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 38.12  E-value: 7.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177  100 LALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALI---LQIQPSNST----LLIILGLTSTLVGGWG 167
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLrfsWPLFPAASEyfapLIVMLSVIAVIYGSLT 292

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 20377177  168 GLNQTQLRKILAYSSIAHLGWMILVLqFSPSITLLT 203
Cdd:MTH00204 293 TCRQVDFKRLIAYSSVAHMGLVPLGL-FTHTIEGLV 327
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-190 9.22e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 37.64  E-value: 9.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20377177   97 MITLALALKIGLAPLHAWLPE-----------VLQGLdLTtglilstwqKLAPFALILQ---IQPSNS--TLLIILGLTS 160
Cdd:PRK12665 214 VLLVAFGIKAAVFPLSFWLPDsyptapapvtaVFAGL-LT---------KVGVYAIIRThtlLFPGGGldTLLMVVALLT 283

                         90       100       110
                 ....*....|....*....|....*....|
gi 20377177  161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMI 190
Cdd:PRK12665 284 MVVGILGAIAQSDIKRLLSFTLVSHIGYMV 313
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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