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Conserved domains on  [gi|20466163|gb|AAM20399|]
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putative acyl-CoA:1-acylglycerol-3-phosphate acyltransferase [Arabidopsis thaliana]

Protein Classification

acyltransferase( domain architecture ID 11476910)

acyltransferase such as lysophospholipid acyltransferase (LPLAT) involved in glycerophospholipid biosynthesis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
7-378 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


:

Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 678.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163    7 LKSDNLKNRPLTPLRILRGLMILLVFLSTAFMFLLYFAPIAALGLRLLSVQQSRKVVSLIFGLWLALWPYLFETVNGTTV 86
Cdd:PLN02510   2 ESDSGPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTKV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   87 VFSGDIIPVEKRVLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQ 166
Cdd:PLN02510  82 VFSGDKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQ 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  167 MLSSFKDPQEPLWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDAVYDLTIAYKPRCP 246
Cdd:PLN02510 162 MLSSFKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRCP 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  247 SFMDNVFGTDPSEVHIHVRRVLLKEIPANEAESSAWLMDSFKLKDKLLSDFNAQGKFPNQRPEEELSVLKCIATFAGVIS 326
Cdd:PLN02510 242 SFLDNVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVIA 321
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 20466163  327 LTVVFIYLTLYSHSCFKVYACLSGTYLTFATYYKFQPSPG-CFREDSCKVKNH 378
Cdd:PLN02510 322 LTTVFTYLTLFSSVWFKIYVSLSCAYLTSATHFNWRPPPLiESLENSLKLVNK 374
 
Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
7-378 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 678.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163    7 LKSDNLKNRPLTPLRILRGLMILLVFLSTAFMFLLYFAPIAALGLRLLSVQQSRKVVSLIFGLWLALWPYLFETVNGTTV 86
Cdd:PLN02510   2 ESDSGPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTKV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   87 VFSGDIIPVEKRVLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQ 166
Cdd:PLN02510  82 VFSGDKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQ 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  167 MLSSFKDPQEPLWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDAVYDLTIAYKPRCP 246
Cdd:PLN02510 162 MLSSFKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRCP 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  247 SFMDNVFGTDPSEVHIHVRRVLLKEIPANEAESSAWLMDSFKLKDKLLSDFNAQGKFPNQRPEEELSVLKCIATFAGVIS 326
Cdd:PLN02510 242 SFLDNVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVIA 321
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 20466163  327 LTVVFIYLTLYSHSCFKVYACLSGTYLTFATYYKFQPSPG-CFREDSCKVKNH 378
Cdd:PLN02510 322 LTTVFTYLTLFSSVWFKIYVSLSCAYLTSATHFNWRPPPLiESLENSLKLVNK 374
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
75-265 1.84e-85

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 257.55  E-value: 1.84e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  75 PYLFETVNGTTVVFSGDIIPVEK-RVLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPV 153
Cdd:cd07990   1 VFLFEWLSGVKVVVYGDEPKLPKeRALIISNHRSEVDWLVLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163 154 ERKREVDEPVLLQMLSSFKDPQEPLWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDA 233
Cdd:cd07990  81 KRKWEKDEKTIKRQLKRLKDSPEPFWLLIFPEGTRFTEEKKERSQEFAEKNGLPPLKHVLLPRTKGFVAILETLRDAVDA 160
                       170       180       190
                ....*....|....*....|....*....|...
gi 20466163 234 VYDLTIAYKPRCP-SFMDNVFGTDPSEVHIHVR 265
Cdd:cd07990 161 VYDVTIAYPDGKPpSEQRLLLGGKPREVHVHVR 193
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
99-213 2.91e-24

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 96.27  E-value: 2.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163     99 VLLIANHRTEVDWMYLWNIALRKGclGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKRE-VDEPVLLQMLSSFKDPQep 177
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKL--GRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGrKARAALREAVELLKEGE-- 76
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 20466163    178 lWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVL 213
Cdd:smart00563  77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEAGVPIV 111
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
51-187 2.98e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 79.67  E-value: 2.98e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  51 LRLLSVQQSRKVVSLIFGLWLALWpylfetvnGTTVVFSG-DIIPVEKRVLLIANHRTEVDWMYLWNIALRKgclgyIKY 129
Cdd:COG0204   4 LFLLLRRFRYRLVRLWARLLLRLL--------GVRVRVEGlENLPADGPVLIVANHQSWLDILLLLAALPRP-----VRF 70
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 20466163 130 VLKSSLMKLPIFGWGFHVLEFIPVER-KREVDEPVLLQMLSSFKDPQeplWLALFPEGT 187
Cdd:COG0204  71 VAKKELFKIPLLGWLLRALGAIPVDRsKRRAALRALRQAVEALKAGE---SLVIFPEGT 126
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
91-196 3.98e-17

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 76.93  E-value: 3.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163    91 DIIPVEKRVLLIANHRTEVDWMYLWNIALRKGCLGYIkyVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQMLSS 170
Cdd:pfam01553   8 ENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRPLVF--VAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVE 85
                          90       100
                  ....*....|....*....|....*.
gi 20466163   171 FKDPQEPLWlaLFPEGTDFTEEKCKR 196
Cdd:pfam01553  86 LLREGKLVV--IFPEGTRSREGELLP 109
 
Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
7-378 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 678.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163    7 LKSDNLKNRPLTPLRILRGLMILLVFLSTAFMFLLYFAPIAALGLRLLSVQQSRKVVSLIFGLWLALWPYLFETVNGTTV 86
Cdd:PLN02510   2 ESDSGPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTKV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   87 VFSGDIIPVEKRVLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQ 166
Cdd:PLN02510  82 VFSGDKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQ 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  167 MLSSFKDPQEPLWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDAVYDLTIAYKPRCP 246
Cdd:PLN02510 162 MLSSFKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRCP 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  247 SFMDNVFGTDPSEVHIHVRRVLLKEIPANEAESSAWLMDSFKLKDKLLSDFNAQGKFPNQRPEEELSVLKCIATFAGVIS 326
Cdd:PLN02510 242 SFLDNVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVIA 321
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 20466163  327 LTVVFIYLTLYSHSCFKVYACLSGTYLTFATYYKFQPSPG-CFREDSCKVKNH 378
Cdd:PLN02510 322 LTTVFTYLTLFSSVWFKIYVSLSCAYLTSATHFNWRPPPLiESLENSLKLVNK 374
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
75-265 1.84e-85

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 257.55  E-value: 1.84e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  75 PYLFETVNGTTVVFSGDIIPVEK-RVLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPV 153
Cdd:cd07990   1 VFLFEWLSGVKVVVYGDEPKLPKeRALIISNHRSEVDWLVLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163 154 ERKREVDEPVLLQMLSSFKDPQEPLWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDA 233
Cdd:cd07990  81 KRKWEKDEKTIKRQLKRLKDSPEPFWLLIFPEGTRFTEEKKERSQEFAEKNGLPPLKHVLLPRTKGFVAILETLRDAVDA 160
                       170       180       190
                ....*....|....*....|....*....|...
gi 20466163 234 VYDLTIAYKPRCP-SFMDNVFGTDPSEVHIHVR 265
Cdd:cd07990 161 VYDVTIAYPDGKPpSEQRLLLGGKPREVHVHVR 193
PLN02380 PLN02380
1-acyl-sn-glycerol-3-phosphate acyltransferase
30-327 1.06e-55

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178006 [Multi-domain]  Cd Length: 376  Bit Score: 186.87  E-value: 1.06e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   30 LVFLSTAFMFLL------YFAPIAALGLRLLSVQQSRKVVSLIFG-LWLALwPYLFETVNGTTVVFSGDIIPVE----KR 98
Cdd:PLN02380   7 LVILPLGLLFLLsglivnLIQAVCFILVRPLSKSLYRRINRAVAElLWLEL-IWLVDWWAGVKVQLYADEETFElmgkEH 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   99 VLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQMLSSFKDPQEPL 178
Cdd:PLN02380  86 ALVISNHRSDIDWLVGWILAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYVFLERSWAKDENTLKSGFQRLKDFPRPF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  179 WLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDAVYDLTIAYKPRCPS-FMDNVFGTDP 257
Cdd:PLN02380 166 WLALFVEGTRFTQAKLLAAQEYAASRGLPVPRNVLIPRTKGFVSAVSNMRSFVPAIYDVTVAVPKGQPApTMLRIFRGQS 245
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20466163  258 SEVHIHVRRVLLKEIPANEAESSAWLMDSFKLKDKLLSDFNAQGKFPNQ------RPEEELSV---LKCIATFAGVISL 327
Cdd:PLN02380 246 SVVHVHIKRHSMKELPETDDGIAQWCKDVFVAKDALLDKHFAEDTFGDQeyqdigRPKKSLIVvisWACLLILGAIKFL 324
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
99-213 2.91e-24

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 96.27  E-value: 2.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163     99 VLLIANHRTEVDWMYLWNIALRKGclGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKRE-VDEPVLLQMLSSFKDPQep 177
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKL--GRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGrKARAALREAVELLKEGE-- 76
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 20466163    178 lWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVL 213
Cdd:smart00563  77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEAGVPIV 111
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
51-187 2.98e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 79.67  E-value: 2.98e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  51 LRLLSVQQSRKVVSLIFGLWLALWpylfetvnGTTVVFSG-DIIPVEKRVLLIANHRTEVDWMYLWNIALRKgclgyIKY 129
Cdd:COG0204   4 LFLLLRRFRYRLVRLWARLLLRLL--------GVRVRVEGlENLPADGPVLIVANHQSWLDILLLLAALPRP-----VRF 70
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 20466163 130 VLKSSLMKLPIFGWGFHVLEFIPVER-KREVDEPVLLQMLSSFKDPQeplWLALFPEGT 187
Cdd:COG0204  71 VAKKELFKIPLLGWLLRALGAIPVDRsKRRAALRALRQAVEALKAGE---SLVIFPEGT 126
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
91-196 3.98e-17

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 76.93  E-value: 3.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163    91 DIIPVEKRVLLIANHRTEVDWMYLWNIALRKGCLGYIkyVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQMLSS 170
Cdd:pfam01553   8 ENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRPLVF--VAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVE 85
                          90       100
                  ....*....|....*....|....*.
gi 20466163   171 FKDPQEPLWlaLFPEGTDFTEEKCKR 196
Cdd:pfam01553  86 LLREGKLVV--IFPEGTRSREGELLP 109
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
257-308 5.55e-14

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 66.44  E-value: 5.55e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 20466163   257 PSEVHIHVRRVLLKEIPANEAESSAWLMDSFKLKDKLLSDFNAQGKFPNQRP 308
Cdd:pfam16076   7 PSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFFPGKE 58
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
91-187 1.92e-13

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 68.07  E-value: 1.92e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  91 DIIPVEKRVLLIANHRTEVDWMYLWNIALRKgclgyIKYVLKSSLMKLPIFGWGFHVLEFIPVER-KREVDEPVLLQMLS 169
Cdd:cd07989  18 ENLPPKGPVIIVANHQSYLDPLVLGAALPRP-----IRFVAKKELFKIPFLGWLLRLLGAIPIDRgNGRSAREALREAIE 92
                        90
                ....*....|....*...
gi 20466163 170 SFKDPQeplWLALFPEGT 187
Cdd:cd07989  93 ALKEGE---SVVIFPEGT 107
PRK14014 PRK14014
putative acyltransferase; Provisional
20-302 3.44e-10

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 60.25  E-value: 3.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   20 LRILRGLM-ILLVFLSTAFMFLLYFapIAALGLRLLSVQQSRKVVS----LIFGLWLALWPYLFETVNGTTVVFSGDI-I 93
Cdd:PRK14014   6 LAPLRGLLsILLLILNTLFWSVPII--ILGLLKLLLPIPAIRRACSrllnFIAEAWISINNVILRLLPRTQWDVEGLEgL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163   94 PVEKRVLLIANHRTEVDWMYLWNIALRKgcLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVER-----------KREVDEP 162
Cdd:PRK14014  84 SKKGWYLVISNHQSWVDILVLQYVFNRR--IPMLKFFLKQELIWVPFLGLAWWALDFPFMKRyskaylaknpeLKGKDLE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  163 VLLQMLSSFKDpqEPLWLALFPEGTDFTEEKCKRSQkfaaevglpalS---NVLLPKTRGFGVCLEVLHNSLDAVYDLTI 239
Cdd:PRK14014 162 TTRRACEKFKR--MPTTIVNFVEGTRFTPEKHQQQQ-----------SpyqHLLKPKAGGIAFALNAMGEQFDGLLDVTI 228
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 20466163  240 AYKPRCPSFMDNVFGtDPSEVHIHVRRVLLKEIPANEAESSA--------WLMDSFKLKDKLLSDFNAQGK 302
Cdd:PRK14014 229 VYPDGRPSFWDLLSG-RVKKIVVHVRLLPIPEELIGDYFNDKefrrrfqqWLNQLWQEKDQLIEQLLAQYN 298
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
70-194 7.10e-09

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 55.11  E-value: 7.10e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  70 WLALWPYLFETVNGTTVvfsgDIIPVEKRVLLIANHRTEVDWMYLWnIALRKGCLGYIKYVLK-SSLMKLPIFGWGFhvl 148
Cdd:cd06551   3 YLLLNFFGFVRLEVKGP----PPPPGGGPVLFVSNHSSWWDGLILF-LLLERGLRRDVYGLMDeELLERYPFFTRLG--- 74
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 20466163 149 eFIPVERKREVDEPVLLQ-MLSSFKDPQEPLWlaLFPEGTDFTEEKC 194
Cdd:cd06551  75 -AFSVDRDSPRSAAKSLKyVARLLSKPGSVVW--IFPEGTRTRRDKR 118
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
69-187 4.79e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 49.95  E-value: 4.79e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  69 LWLALWPYlFETVngttVVFSGDIIPVEKRVLLIANHRTE-VDWMYLWNIALRKgclgyIKYVLKSSLMKLPIFGWGFHV 147
Cdd:cd07992   5 SRVILRIY-FRRI----TVVGRENVPKDGPVIFLGNHPNAlIDPLLLAATLRRP-----VRFLAKADLFKNPLIGWLLES 74
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 20466163 148 LEFIPVERKRevDEPVLLQMLSSFKDPQEPLWLAL--------FPEGT 187
Cdd:cd07992  75 FGAIPVYRPK--DLARGGIGKISNAAVFDAVGEALkaggaigiFPEGG 120
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
90-187 7.57e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 45.67  E-value: 7.57e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  90 GDIIPVEKRVLLIANHRTEVDWMY--LWNIALRKGclgyIKYVLKSSLMKLPiFGWGFHVLEFIPVERKREVDepVLLQM 167
Cdd:cd07988  14 GEPPNKPKFVVIGAPHTSNWDFVLglLAAFALGLK----ISFLGKHSLFKPP-LGPFMRWLGGIPVDRSRAGG--LVEQV 86
                        90       100
                ....*....|....*....|
gi 20466163 168 LSSFKDpQEPLWLALFPEGT 187
Cdd:cd07988  87 VEEFRR-REEFVLAIAPEGT 105
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
88-187 8.97e-04

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 40.28  E-value: 8.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163  88 FSGDIIPVEKRVLLIANHRTEVDWMYLwnialrkGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVER------------ 155
Cdd:cd07991  15 VHGKPDPPEAPRIIVANHTSFIDPLIL-------FSDLFPSIVAKKELGKLPFIGTILRALGCIFVDRsepkdrkkvvee 87
                        90       100       110
                ....*....|....*....|....*....|...
gi 20466163 156 -KREVDEPVLLQMLssfkdpqeplwlaLFPEGT 187
Cdd:cd07991  88 iKERATDPNWPPIL-------------IFPEGT 107
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
93-187 1.45e-03

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 40.68  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20466163    93 IPVEKRVLLIANHRTEVDWMYLWNIALRKgclgyIKYVLKSSLMKLPIFGWGFHVLEFIPVERKrevDEPVLLQMLSSFK 172
Cdd:PRK08633  437 IPAKGGALLLGNHVSWIDWALLQAASPRP-----IRFVMERSIYEKWYLKWFFKLFGVIPISSG---GSKESLEFIRKAL 508
                          90
                  ....*....|....*
gi 20466163   173 DPQEplWLALFPEGT 187
Cdd:PRK08633  509 DDGE--VVCIFPEGA 521
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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