NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|187469675|gb|AAI66746|]
View 

Itpripl2 protein [Rattus norvegicus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Mab-21_C super family cl48430
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 374-496 1.86e-09

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam20266:

Pssm-ID: 466416  Cd Length: 102  Bit Score: 54.94  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187469675  374 KCLQLLKALRDLGARGLDPMAAThwgriLSSYMLKTAVLEVLlnEGGPTPS-WDEAYLSECLEKLVKFLRDClLRRRDLF 452
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVKTELSK-----ICSYHLKTLFLWEC--EKHPDDSdWDKENLSDRFLGLLEELHKC-LRNGKLP 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 187469675  453 HCVLgpagaaaevgplpkvlreaPPVDLLAPFDQHARELAAARL 496
Cdd:pfam20266  76 HFFI-------------------PKLNLFQSLSRKELDDLAKKL 100
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 374-496 1.86e-09

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 54.94  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187469675  374 KCLQLLKALRDLGARGLDPMAAThwgriLSSYMLKTAVLEVLlnEGGPTPS-WDEAYLSECLEKLVKFLRDClLRRRDLF 452
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVKTELSK-----ICSYHLKTLFLWEC--EKHPDDSdWDKENLSDRFLGLLEELHKC-LRNGKLP 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 187469675  453 HCVLgpagaaaevgplpkvlreaPPVDLLAPFDQHARELAAARL 496
Cdd:pfam20266  76 HFFI-------------------PKLNLFQSLSRKELDDLAKKL 100
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 374-496 1.86e-09

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 54.94  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187469675  374 KCLQLLKALRDLGARGLDPMAAThwgriLSSYMLKTAVLEVLlnEGGPTPS-WDEAYLSECLEKLVKFLRDClLRRRDLF 452
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVKTELSK-----ICSYHLKTLFLWEC--EKHPDDSdWDKENLSDRFLGLLEELHKC-LRNGKLP 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 187469675  453 HCVLgpagaaaevgplpkvlreaPPVDLLAPFDQHARELAAARL 496
Cdd:pfam20266  76 HFFI-------------------PKLNLFQSLSRKELDDLAKKL 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH