NCBI Conserved Domain Search

Ankyrin repeat [Signal transduction mechanisms];

54-343

9.81e-51

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 180.92 E-value: 9.81e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   54 AEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNV 133
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  134 NVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 213
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  214 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLV 293
Cdd:COG0666  161 AANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEI-VKLLL 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 63100468  294 GNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPL 343
Cdd:COG0666  240 EAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

633-963

3.19e-36

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 138.93 E-value: 3.19e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  633 LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC 712
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  713 LLRDSRGRTPIHLSAACGHIGVLGALLQSatsvDANPAVVDNHGYTALHWACYNGHETCVELLLEQdvfqkidgnafspl 792
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEA----GADVNARDKDGETPLHLAAYNGNLEIVKLLLEA-------------- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  793 hcavindnegaaemlidslGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTV 872
Cdd:COG0666  143 -------------------GAD-VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  873 EMLVsSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASV 952
Cdd:COG0666  203 KLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGAD---LNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278

                        330
                 ....*....|.
gi 63100468  953 LAVDENGYTPA 963
Cdd:COG0666  279 AAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

507-742

3.08e-35

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 136.24 E-value: 3.08e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  507 NAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTP 586
Cdd:COG0666   44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETP 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  587 LDLAAFKGHVECVDVLINQGASILVKDYvLKRTPIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGH 665
Cdd:COG0666  124 LHLAAYNGNLEIVKLLLEAGADVNAQDN-DGNTPLHLAAANGNLEIVKLLLEA----GAdVNARDNDGETPLHLAAENGH 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468  666 TDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 742
Cdd:COG0666  199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLAL 275

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

225-503

9.00e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 128.92 E-value: 9.00e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  225 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 304
Cdd:COG0666    6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  305 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 384
Cdd:COG0666   86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  385 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 464
Cdd:COG0666  166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 63100468  465 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 503
Cdd:COG0666  246 NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284

Ank_4

Ankyrin repeats (many copies);

12-61

1.89e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 1.89e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468     12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLI 61
Cdd:pfam13637    5 LHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Name

Accession

Description

Interval

E-value

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

54-343

9.81e-51

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 180.92 E-value: 9.81e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   54 AEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNV 133
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  134 NVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 213
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  214 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLV 293
Cdd:COG0666  161 AANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEI-VKLLL 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 63100468  294 GNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPL 343
Cdd:COG0666  240 EAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289

PHA03100

ankyrin repeat protein; Provisional

23-301

1.37e-40

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 155.59 E-value: 1.37e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    23 EVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLH-----RAVASCSEEAVQILLKHS 97
Cdd:PHA03100   17 NIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHylsniKYNLTDVKEIVKLLLEYG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    98 ADVNARDKNWQTPLHIAAANKavkcaeslvpllsnvnvsdragrtalhhaafSGHGEMVKLLLSRGANINAFDKKDRRAI 177
Cdd:PHA03100   97 ANVNAPDNNGITPLLYAISKK-------------------------------SNSYSIVEYLLDNGANVNIKNSDGENLL 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   178 HWAAYMGHI--EVVKLLVSHGAEVTCKDKksytplhaaassgmisvVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 255
Cdd:PHA03100  146 HLYLESNKIdlKILKLLIDKGVDINAKNR-----------------VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFV 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 63100468   256 NELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNM 301
Cdd:PHA03100  209 KYLLDLGANPNLVNKYGDTPLHIAILNNNKEI-FKLLLNNGPSIKT 253

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

633-963

3.19e-36

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 138.93 E-value: 3.19e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  633 LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC 712
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  713 LLRDSRGRTPIHLSAACGHIGVLGALLQSatsvDANPAVVDNHGYTALHWACYNGHETCVELLLEQdvfqkidgnafspl 792
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEA----GADVNARDKDGETPLHLAAYNGNLEIVKLLLEA-------------- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  793 hcavindnegaaemlidslGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTV 872
Cdd:COG0666  143 -------------------GAD-VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  873 EMLVsSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASV 952
Cdd:COG0666  203 KLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGAD---LNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278

                        330
                 ....*....|.
gi 63100468  953 LAVDENGYTPA 963
Cdd:COG0666  279 AAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

507-742

3.08e-35

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 136.24 E-value: 3.08e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  507 NAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTP 586
Cdd:COG0666   44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETP 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  587 LDLAAFKGHVECVDVLINQGASILVKDYvLKRTPIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGH 665
Cdd:COG0666  124 LHLAAYNGNLEIVKLLLEAGADVNAQDN-DGNTPLHLAAANGNLEIVKLLLEA----GAdVNARDNDGETPLHLAAENGH 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468  666 TDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 742
Cdd:COG0666  199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLAL 275

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

225-503

9.00e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 128.92 E-value: 9.00e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  225 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 304
Cdd:COG0666    6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  305 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 384
Cdd:COG0666   86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  385 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 464
Cdd:COG0666  166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 63100468  465 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 503
Cdd:COG0666  246 NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284

PHA03095

ankyrin-like protein; Provisional

219-475

1.25e-31

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 130.14 E-value: 1.25e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   219 ISVVKYLLDLGVDMNEPNAYGNTPLHV--ACYNGQDV-VVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGN 295
Cdd:PHA03095   27 VEEVRRLLAAGADVNFRGEYGKTPLHLylHYSSEKVKdIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLDVIKLLIKA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   296 GADVNMKSKDGKTPLH--MTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH---ELLiNTLITSGADTAKRGI 370
Cdd:PHA03095  107 GADVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNanvELL-RLLIDAGADVYAVDD 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   371 HGMFPLHLAALS--GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL--NTGADFNKKDKFGRSPLHYAA 446
Cdd:PHA03095  186 RFRSLLHHHLQSfkPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPllIAGISINARNRYGQTPLHYAA 265

                         250       260       270
                  ....*....|....*....|....*....|
gi 63100468   447 ANCNyQCLFA-LVGSGASVNDLDERGCTPL 475
Cdd:PHA03095  266 VFNN-PRACRrLIALGADINAVSSDGNTPL 294

PHA02874

ankyrin repeat protein; Provisional

554-863

2.06e-21

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 98.50 E-value: 2.06e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   554 LHLAAYHGHHQALEVLVQS---LLDLDVRNSSgrTPLDLAAFKGHVECVDVLINQGASIlvkDYVLKRTP--IHAAATNG 628
Cdd:PHA02874    5 LRMCIYSGDIEAIEKIIKNkgnCINISVDETT--TPLIDAIRSGDAKIVELFIKHGADI---NHINTKIPhpLLTAIKIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   629 HSECLRLLIGNAEPQNAVDIQDGNGQTplmlsvlnghtdcVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 708
Cdd:PHA02874   80 AHDIIKLLIDNGVDTSILPIPCIEKDM-------------IKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEY 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   709 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDANpavvDNHGYTALHWACYNGHETCVELLLEQ--DVFQKIDg 786
Cdd:PHA02874  147 GADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVK----DNNGESPLHNAAEYGDYACIKLLIDHgnHIMNKCK- 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63100468   787 NAFSPLHCAVINdNEGAAEMLIDSlgASIvNATDSKGRTPLH-AAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMA 863
Cdd:PHA02874  222 NGFTPLHNAIIH-NRSAIELLINN--ASI-NDQDIDGSTPLHhAINPPCDIDIIDILLYHKADISIKDNKGENPIDTA 295

Ank_2

Ankyrin repeats (3 copies);

144-236

6.62e-21

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.25 E-value: 6.62e-21

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    144 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHgAEVTCKDKKsYTPLHAAASSGMISVVK 223
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNG-RTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    224 YLLDLGVDMNEPN 236
Cdd:pfam12796   79 LLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

621-716

2.10e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 80.93 E-value: 2.10e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    621 IHAAATNGHSECLRLLIgnaEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKgANVDAKDKwGRTALHRGAVTGHEE 700
Cdd:pfam12796    1 LHLAAKNGNLELVKLLL---ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLE 75

                           90
                   ....*....|....*.
gi 63100468    701 CVDALLQHGAKCLLRD 716
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91

PHA02876

ankyrin repeat protein; Provisional

428-777

1.15e-17

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 88.20 E-value: 1.15e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   428 GADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYN 507
Cdd:PHA02876  168 GADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSK-NIDTIKAIIDNRSNINKNDLSLLK 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   508 AVHYSAAyghrlclqliasETPLdvLMETSGTDMLSDSDNRATisPLHLAAyhgHHQALEVLVQSLL----DLDVRNSSG 583
Cdd:PHA02876  247 AIRNEDL------------ETSL--LLYDAGFSVNSIDDCKNT--PLHHAS---QAPSLSRLVPKLLergaDVNAKNIKG 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   584 RTPLDLAAFKGH-VECVDVLINQGASILVKDYvLKRTPIHAAATnghseclrllignaepqnavdiqdgngqtplmlsvL 662
Cdd:PHA02876  308 ETPLYLMAKNGYdTENIRTLIMLGADVNAADR-LYITPLHQAST-----------------------------------L 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   663 NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLsAACGhigvLGALLQSA 742
Cdd:PHA02876  352 DRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHF-ALCG----TNPYMSVK 426

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 63100468   743 TSVDANPAVVDNHGY--TALHWACYNGHE-TCVELLLE 777
Cdd:PHA02876  427 TLIDRGANVNSKNKDlsTPLHYACKKNCKlDVIEMLLD 464

Ank_2

Ankyrin repeats (3 copies);

554-647

9.13e-16

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 73.61 E-value: 9.13e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    554 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGAsilVKDYVLKRTPIHAAATNGHSECL 633
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD---VNLKDNGRTALHYAARSGHLEIV 77

                           90
                   ....*....|....
gi 63100468    634 RLLIGNAEPQNAVD 647
Cdd:pfam12796   78 KLLLEKGADINVKD 91

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

74-259

9.54e-14

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 75.43 E-value: 9.54e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   74 WLTPLHRAVASCSEEAVQILLK-HSADVNARDKNWQTPLHIAAANKAVKCAESL---VPLLSNVNV-SD-RAGRTALHHA 147
Cdd:cd22192   17 SESPLLLAAKENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLmeaAPELVNEPMtSDlYQGETALHIA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  148 AFSGHGEMVKLLLSRGANIN-------AFDKKDRRAIHW-------AAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 213
Cdd:cd22192   97 VVNQNLNLVRELIARGADVVspratgtFFRPGPKNLIYYgehplsfAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHIL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468  214 ASSGMISVVKYLLDLGVDMNE----------PNAYGNTPLHVACYNGQDVVVNELI 259
Cdd:cd22192  177 VLQPNKTFACQMYDLILSYDKeddlqpldlvPNNQGLTPFKLAAKEGNIVMFQHLV 232

Ank_2

Ankyrin repeats (3 copies);

310-402

9.12e-13

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.14 E-value: 9.12e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    310 LHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAdtAKRGIHGMFPLHLAALSGFSDCCR 389
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    390 KLLSSGFDIDTPD 402
Cdd:pfam12796   79 LLLEKGADINVKD 91

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

585-725

7.62e-10

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 62.72 E-value: 7.62e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  585 TPLDLAAFKGHVECVDVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNA-----EPQNAVDIQdgnGQTPLML 659
Cdd:cd22192   19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelvnEPMTSDLYQ---GETALHI 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  660 SVLNGHTDCVYSLLNKGANV--------------DAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL 725
Cdd:cd22192   96 AVVNQNLNLVRELIARGADVvspratgtffrpgpKNLIYYGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

574-797

6.33e-08

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 56.63 E-value: 6.33e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    574 LDLDVRNSSGRTPLDLAAFKG-HVECVDVLINQGASILVKDyvlkrTPIHAAATNGH---SECLRLLIGNAE----PQNA 645
Cdd:TIGR00870   43 LNINCPDRLGRSALFVAAIENeNLELTELLLNLSCRGAVGD-----TLLHAISLEYVdavEAILLHLLAAFRksgpLELA 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    646 VDIQDGN---GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK--------------WGRTALHRGAVTGHEECVDALLQH 708
Cdd:TIGR00870  118 NDQYTSEftpGITALHLAAHRQNYEIVKLLLERGASVPARACgdffvksqgvdsfyHGESPLNAAACLGSPSIVALLSED 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    709 GAKCLLRDSRGRTPIHLSA------------ACG-HIGVLGALLQSATSVDANpAVVDNHGYTALHWACYNGHETCVELL 775
Cdd:TIGR00870  198 PADILTADSLGNTLLHLLVmenefkaeyeelSCQmYNFALSLLDKLRDSKELE-VILNHQGLTPLKLAAKEGRIVLFRLK 276

                          250       260
                   ....*....|....*....|...
gi 63100468    776 LEQDVFQ-KIDGNAFSPLHCAVI 797
Cdd:TIGR00870  277 LAIKYKQkKFVAWPNGQQLLSLY 299

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

28-247

1.63e-07

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 55.47 E-value: 1.63e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468     28 IFKKEDVNFQDNEKrtplhaaAYLGDAEIIELLILSGARVNAK-------DSKWLTPLHRAVA-SCSEEAVQILLKHSAD 99
Cdd:TIGR00870    6 IVPAEESPLSDEEK-------AFLPAAERGDLASVYRDLEEPKklnincpDRLGRSALFVAAIeNENLELTELLLNLSCR 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    100 VNARDknwqTPLHIAAANKAVKCAESLVPLLSN---------VNVSDR----AGRTALHHAAFSGHGEMVKLLLSRGANI 166
Cdd:TIGR00870   79 GAVGD----TLLHAISLEYVDAVEAILLHLLAAfrksgplelANDQYTseftPGITALHLAAHRQNYEIVKLLLERGASV 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    167 NA------FDKKDRRA--------IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA------------SSGMIS 220
Cdd:TIGR00870  155 PAracgdfFVKSQGVDsfyhgespLNAAACLGSPSIVALLSEDPADILTADSLGNTLLHLLVmenefkaeyeelSCQMYN 234

                          250       260       270
                   ....*....|....*....|....*....|.
gi 63100468    221 VVKYLLDLGVDMNE----PNAYGNTPLHVAC 247
Cdd:TIGR00870  235 FALSLLDKLRDSKEleviLNHQGLTPLKLAA 265

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

274-479

1.45e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 52.32 E-value: 1.45e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  274 TPLhFAAASTHGALCLE-LLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA-----VIDCEDKNGNTPLHIAA 347
Cdd:cd22192   19 SPL-LLAAKENDVQAIKkLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPelvnePMTSDLYQGETALHIAV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  348 RYGHELLINTLITSGADTAKRGIHGMFplhlaalsgFSDCCRKLLSsgfdidtpddFGRTCLHAAAAGGNLECLNLLLNT 427
Cdd:cd22192   98 VNQNLNLVRELIARGADVVSPRATGTF---------FRPGPKNLIY----------YGEHPLSFAACVGNEEIVRLLIEH 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468  428 GADFNKKDKFGRSPLHYAA--ANCNYQC-----LFALVGSGASVNdLD----ERGCTPLHYAA 479
Cdd:cd22192  159 GADIRAQDSLGNTVLHILVlqPNKTFACqmydlILSYDKEDDLQP-LDlvpnNQGLTPFKLAA 220

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

140-168

1.74e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 42.57 E-value: 1.74e-05

                            10        20
                    ....*....|....*....|....*....
gi 63100468     140 GRTALHHAAFSGHGEMVKLLLSRGANINA 168
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30

Ank_4

Ankyrin repeats (many copies);

12-61

1.89e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 1.89e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468     12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLI 61
Cdd:pfam13637    5 LHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

473-675

2.22e-05

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 48.47 E-value: 2.22e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  473 TPLHYAAtSDTDGKCLEYLLR-NDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSgtdmlsdSDNRATI 551
Cdd:cd22192   19 SPLLLAA-KENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMT-------SDLYQGE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  552 SPLHLAAYHGHhqalEVLVQSLLD--LDVRNSS----------------GRTPLDLAAFKGHVECVDVLINQGASILVKD 613
Cdd:cd22192   91 TALHIAVVNQN----LNLVRELIArgADVVSPRatgtffrpgpknliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468  614 YvLKRTPIHAAAT--NGHSECLRL-LIGNAEP---QNAVD-IQDGNGQTPLMLSVLNGHTDCVYSLLNK 675
Cdd:cd22192  167 S-LGNTVLHILVLqpNKTFACQMYdLILSYDKeddLQPLDlVPNNQGLTPFKLAAKEGNIVMFQHLVQK 234

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

338-364

1.07e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.57 E-value: 1.07e-03

                            10        20
                    ....*....|....*....|....*..
gi 63100468     338 NGNTPLHIAARYGHELLINTLITSGAD 364
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGAD 27

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

755-777

1.21e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.18 E-value: 1.21e-03

                            10        20
                    ....*....|....*....|...
gi 63100468     755 HGYTALHWACYNGHETCVELLLE 777
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLD 23

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

583-609

2.58e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.41 E-value: 2.58e-03

                            10        20
                    ....*....|....*....|....*..
gi 63100468     583 GRTPLDLAAFKGHVECVDVLINQGASI 609
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGADI 28

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

391-571

4.55e-03

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 40.83 E-value: 4.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    391 LLSSGFDIDTpddfGRTCLHAA-----------------AAGGNLECLNLLLNTGADFNkkdkFGRSPLHYAAANCNYQC 453
Cdd:TIGR00870   72 LLNLSCRGAV----GDTLLHAIsleyvdaveaillhllaAFRKSGPLELANDQYTSEFT----PGITALHLAAHRQNYEI 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    454 LFALVGSGASVN--------------DLDERGCTPLH-YAATSDTDgkCLEYLLRNDANPGIRDKQGYNAVH-------Y 511
Cdd:TIGR00870  144 VKLLLERGASVParacgdffvksqgvDSFYHGESPLNaAACLGSPS--IVALLSEDPADILTADSLGNTLLHllvmeneF 221

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 63100468    512 SAAYGH--RLCLQLIasetpLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQ 571
Cdd:TIGR00870  222 KAEYEElsCQMYNFA-----LSLLDKLRDSKELEVILNHQGLTPLKLAAKEGRIVLFRLKLA 278

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

15-79

4.99e-03

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 40.77 E-value: 4.99e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468   15 AIFNGDPDEVRALIFKKEDVN--------FQDNEKRT------PLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLH 79
Cdd:cd22192   96 AVVNQNLNLVRELIARGADVVspratgtfFRPGPKNLiyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLH 174

Name

Accession

Description

Interval

E-value

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

54-343

9.81e-51

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 180.92 E-value: 9.81e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   54 AEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNV 133
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  134 NVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 213
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  214 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLV 293
Cdd:COG0666  161 AANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEI-VKLLL 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 63100468  294 GNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPL 343
Cdd:COG0666  240 EAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

12-276

2.35e-49

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 177.07 E-value: 2.35e-49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQ 91
Cdd:COG0666   25 LLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVK 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   92 ILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDK 171
Cdd:COG0666  105 LLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDN 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  172 KDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQ 251
Cdd:COG0666  185 DGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGA 264

                        250       260
                 ....*....|....*....|....*
gi 63100468  252 DVVVNELIDCGANVNQKNEKGFTPL 276
Cdd:COG0666  265 ALIVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

22-308

4.61e-49

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 176.30 E-value: 4.61e-49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   22 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVN 101
Cdd:COG0666    2 LLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADIN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  102 ARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAA 181
Cdd:COG0666   82 AKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  182 YMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC 261
Cdd:COG0666  162 ANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 63100468  262 GANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKT 308
Cdd:COG0666  242 GADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTL 288

PHA03100

ankyrin repeat protein; Provisional

23-301

1.37e-40

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 155.59 E-value: 1.37e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    23 EVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLH-----RAVASCSEEAVQILLKHS 97
Cdd:PHA03100   17 NIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHylsniKYNLTDVKEIVKLLLEYG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    98 ADVNARDKNWQTPLHIAAANKavkcaeslvpllsnvnvsdragrtalhhaafSGHGEMVKLLLSRGANINAFDKKDRRAI 177
Cdd:PHA03100   97 ANVNAPDNNGITPLLYAISKK-------------------------------SNSYSIVEYLLDNGANVNIKNSDGENLL 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   178 HWAAYMGHI--EVVKLLVSHGAEVTCKDKksytplhaaassgmisvVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 255
Cdd:PHA03100  146 HLYLESNKIdlKILKLLIDKGVDINAKNR-----------------VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFV 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 63100468   256 NELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNM 301
Cdd:PHA03100  209 KYLLDLGANPNLVNKYGDTPLHIAILNNNKEI-FKLLLNNGPSIKT 253

PHA03095

ankyrin-like protein; Provisional

22-310

1.90e-40

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 156.34 E-value: 1.90e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    22 DEVRALIFKKEDVNFQDNEKRTPLHaaAYLG-----DAEIIELLILSGARVNAKDSKWLTPLHRAV-ASCSEEAVQILLK 95
Cdd:PHA03095   28 EEVRRLLAAGADVNFRGEYGKTPLH--LYLHyssekVKDIVRLLLEAGADVNAPERCGFTPLHLYLyNATTLDVIKLLIK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    96 HSADVNARDKNWQTPLHIAAANKAVkcaeslvpllsnvnvsdragrtalhhaafsgHGEMVKLLLSRGANINAFDKKDRR 175
Cdd:PHA03095  106 AGADVNAKDKVGRTPLHVYLSGFNI-------------------------------NPKVIRLLLRKGADVNALDLYGMT 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   176 AIHwaAYMGH----IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMIS--VVKYLLDLGVDMNEPNAYGNTPLHVACYN 249
Cdd:PHA03095  155 PLA--VLLKSrnanVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPRarIVRELIRAGCDPAATDMLGNTPLHSMATG 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468   250 G--QDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGnGADVNMKSKDGKTPL 310
Cdd:PHA03095  233 SscKRSLVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIAL-GADINAVSSDGNTPL 294

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

154-475

1.88e-37

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 142.40 E-value: 1.88e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  154 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMN 233
Cdd:COG0666    2 LLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADIN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  234 EPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKskdgktplhmt 313
Cdd:COG0666   82 AKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEI-VKLLLEAGADVNAQ----------- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  314 alhgrfsrsqtiiqsgavidceDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 393
Cdd:COG0666  150 ----------------------DNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLE 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  394 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCT 473
Cdd:COG0666  208 AGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLT 287


                 ..
gi 63100468  474 PL 475
Cdd:COG0666  288 LL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

633-963

3.19e-36

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 138.93 E-value: 3.19e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  633 LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC 712
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  713 LLRDSRGRTPIHLSAACGHIGVLGALLQSatsvDANPAVVDNHGYTALHWACYNGHETCVELLLEQdvfqkidgnafspl 792
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEA----GADVNARDKDGETPLHLAAYNGNLEIVKLLLEA-------------- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  793 hcavindnegaaemlidslGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTV 872
Cdd:COG0666  143 -------------------GAD-VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  873 EMLVsSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASV 952
Cdd:COG0666  203 KLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGAD---LNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278

                        330
                 ....*....|.
gi 63100468  953 LAVDENGYTPA 963
Cdd:COG0666  279 AAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

507-742

3.08e-35

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 136.24 E-value: 3.08e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  507 NAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTP 586
Cdd:COG0666   44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETP 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  587 LDLAAFKGHVECVDVLINQGASILVKDYvLKRTPIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGH 665
Cdd:COG0666  124 LHLAAYNGNLEIVKLLLEAGADVNAQDN-DGNTPLHLAAANGNLEIVKLLLEA----GAdVNARDNDGETPLHLAAENGH 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468  666 TDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 742
Cdd:COG0666  199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLAL 275

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

540-822

9.58e-35

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 134.70 E-value: 9.58e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  540 DMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYvLKRT 619
Cdd:COG0666   11 LLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD-GGNT 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  620 PIHAAATNGHSECLRLLIGNAEPqnaVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHE 699
Cdd:COG0666   90 LLHAAARNGDLEIVKLLLEAGAD---VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  700 ECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSatsvDANPAVVDNHGYTALHWACYNGHETCVELLLEQ- 778
Cdd:COG0666  167 EIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA----GADVNAKDNDGKTALDLAAENGNLEIVKLLLEAg 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 63100468  779 DVFQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNATDSK 822
Cdd:COG0666  243 ADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLL 286

PHA02876

ankyrin repeat protein; Provisional

22-364

1.62e-34

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 141.74 E-value: 1.62e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    22 DEVR---ALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSA 98
Cdd:PHA02876  156 DELLiaeMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRS 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    99 DVNARDKNwqtpLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGH-GEMVKLLLSRGANINAFDKKDRRAI 177
Cdd:PHA02876  236 NINKNDLS----LLKAIRNEDLETSLLLYDAGFSVNSIDDCKNTPLHHASQAPSlSRLVPKLLERGADVNAKNIKGETPL 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   178 HWAAYMGH-IEVVKLLVSHGAEVTCKDKKSYTPLHAAAS-SGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVV 255
Cdd:PHA02876  312 YLMAKNGYdTENIRTLIMLGADVNAADRLYITPLHQASTlDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVII 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   256 NELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHG-RFSRSQTIIQSGAVIDC 334
Cdd:PHA02876  392 NTLLDYGADIEALSQKIGTALHFALCGTNPYMSVKTLIDRGANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNA 471

                         330       340       350
                  ....*....|....*....|....*....|
gi 63100468   335 EDKNGNTPLHIAarYGHELLINTLITSGAD 364
Cdd:PHA02876  472 INIQNQYPLLIA--LEYHGIVNILLHYGAE 499

PHA02874

ankyrin repeat protein; Provisional

16-367

2.44e-34

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 137.40 E-value: 2.44e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    16 IFNGDPDEVRALIFKKED-VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILL 94
Cdd:PHA02874    9 IYSGDIEAIEKIIKNKGNcINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    95 KHSADVNARDknwqtplhiaaankavkcaeslVPLLSNvnvsdragrtalhhaafsghgEMVKLLLSRGANINAFDKKDR 174
Cdd:PHA02874   89 DNGVDTSILP----------------------IPCIEK---------------------DMIKTILDCGIDVNIKDAELK 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   175 RAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVV 254
Cdd:PHA02874  126 TFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYAC 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   255 VNELIDCGANVNQKNEKGFTPLHfaAASTHGALCLELLVgNGADVNMKSKDGKTPLHMtALHGRFSRS--QTIIQSGAVI 332
Cdd:PHA02874  206 IKLLIDHGNHIMNKCKNGFTPLH--NAIIHNRSAIELLI-NNASINDQDIDGSTPLHH-AINPPCDIDiiDILLYHKADI 281

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 63100468   333 DCEDKNGNTPLHIAARYGH------ELLINTLITSGADTAK 367
Cdd:PHA02874  282 SIKDNKGENPIDTAFKYINkdpvikDIIANAVLIKEADKLK 322

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

746-981

1.96e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 130.84 E-value: 1.96e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  746 DANPAVVDNHGYTALHWACYNGHETCVELLLEQDVF-QKIDGNAFSPLHCAVINDNEGAAEMLIDSlGASiVNATDSKGR 824
Cdd:COG0666   44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADiNAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  825 TPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSsASADLTLQDKSKNTALHLACGKGHET 904
Cdd:COG0666  122 TPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLE-AGADVNARDNDGETPLHLAAENGHLE 200

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468  905 SALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 981
Cdd:COG0666  201 IVKLLLEAGAD---VNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLA 274

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

225-503

9.00e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 128.92 E-value: 9.00e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  225 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 304
Cdd:COG0666    6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  305 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 384
Cdd:COG0666   86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  385 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 464
Cdd:COG0666  166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 63100468  465 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 503
Cdd:COG0666  246 NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284

PHA03095

ankyrin-like protein; Provisional

86-359

4.01e-32

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 131.30 E-value: 4.01e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    86 SEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLL---SNVNVSDRAGRTALH-HAAFSGHGEMVKLLLS 161
Cdd:PHA03095   26 TVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKDIVRLLLeagADVNAPERCGFTPLHlYLYNATTLDVIKLLIK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   162 RGANINAFDKKDRRAIHwaAYMG----HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISV--VKYLLDLGVDMNEP 235
Cdd:PHA03095  106 AGADVNAKDKVGRTPLH--VYLSgfniNPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNANVelLRLLIDAGADVYAV 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   236 NAYGNTPLHVACYNGQD--VVVNELIDCGANVNQKNEKGFTPLHFAAA-STHGALCLELLVGNGADVNMKSKDGKTPLHM 312
Cdd:PHA03095  184 DDRFRSLLHHHLQSFKPraRIVRELIRAGCDPAATDMLGNTPLHSMATgSSCKRSLVLPLLIAGISINARNRYGQTPLHY 263

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 63100468   313 TALHGR---FSRsqtIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLI 359
Cdd:PHA03095  264 AAVFNNpraCRR---LIALGADINAVSSDGNTPLSLMVRNNNGRAVRAAL 310

PHA03095

ankyrin-like protein; Provisional

186-454

6.73e-32

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 130.92 E-value: 6.73e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   186 IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM---ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV-VVNELIDC 261
Cdd:PHA03095   27 VEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSekvKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLdVIKLLIKA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   262 GANVNQKNEKGFTPLH--FAAASTHgALCLELLVGNGADVNMKSKDGKTPLHMtalhgrFSRS--------QTIIQSGAV 331
Cdd:PHA03095  107 GADVNAKDKVGRTPLHvyLSGFNIN-PKVIRLLLRKGADVNALDLYGMTPLAV------LLKSrnanvellRLLIDAGAD 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   332 IDCEDKNGNTPLHIAARYGH--ELLINTLITSGADTAKRGIHGMFPLHLAALsgFSDCCR----KLLSSGFDIDTPDDFG 405
Cdd:PHA03095  180 VYAVDDRFRSLLHHHLQSFKprARIVRELIRAGCDPAATDMLGNTPLHSMAT--GSSCKRslvlPLLIAGISINARNRYG 257

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 63100468   406 RTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCL 454
Cdd:PHA03095  258 QTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAV 306

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

7-177

1.18e-31

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 125.84 E-value: 1.18e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    7 RDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCS 86
Cdd:COG0666  119 DGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGH 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   87 EEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 166
Cdd:COG0666  199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278

                        170
                 ....*....|.
gi 63100468  167 NAFDKKDRRAI 177
Cdd:COG0666  279 AAALLDLLTLL 289

PHA03095

ankyrin-like protein; Provisional

219-475

1.25e-31

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 130.14 E-value: 1.25e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   219 ISVVKYLLDLGVDMNEPNAYGNTPLHV--ACYNGQDV-VVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGN 295
Cdd:PHA03095   27 VEEVRRLLAAGADVNFRGEYGKTPLHLylHYSSEKVKdIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLDVIKLLIKA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   296 GADVNMKSKDGKTPLH--MTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH---ELLiNTLITSGADTAKRGI 370
Cdd:PHA03095  107 GADVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNanvELL-RLLIDAGADVYAVDD 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   371 HGMFPLHLAALS--GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL--NTGADFNKKDKFGRSPLHYAA 446
Cdd:PHA03095  186 RFRSLLHHHLQSfkPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPllIAGISINARNRYGQTPLHYAA 265

                         250       260       270
                  ....*....|....*....|....*....|
gi 63100468   447 ANCNyQCLFA-LVGSGASVNDLDERGCTPL 475
Cdd:PHA03095  266 VFNN-PRACRrLIALGADINAVSSDGNTPL 294

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

753-981

1.87e-31

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 125.07 E-value: 1.87e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  753 DNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIvNATDSKGRTPLHAAAF 832
Cdd:COG0666   18 LLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI-NAKDDGGNTLLHAAAR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  833 TDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSsASADLTLQDKSKNTALHLACGKGHETSALLILEK 912
Cdd:COG0666   97 NGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLE-AGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEA 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468  913 ITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILA 981
Cdd:COG0666  176 GAD---VNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

263-525

9.88e-31

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 123.14 E-value: 9.88e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  263 ANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTP 342
Cdd:COG0666   11 LLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  343 LHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLN 422
Cdd:COG0666   91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  423 LLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRD 502
Cdd:COG0666  171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENG-NLEIVKLLLEAGADLNAKD 249

                        250       260
                 ....*....|....*....|...
gi 63100468  503 KQGYNAVHYSAAYGHRLCLQLIA 525
Cdd:COG0666  250 KDGLTALLLAAAAGAALIVKLLL 272

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

391-723

1.94e-30

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 122.37 E-value: 1.94e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  391 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDER 470
Cdd:COG0666    7 LLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  471 GCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYnavhysaayghrlclqliasetpldvlmetsgtdmlsdsdnrat 550
Cdd:COG0666   87 GNTLLHAAARNG-DLEIVKLLLEAGADVNARDKDGE-------------------------------------------- 121

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  551 iSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYvLKRTPIHAAATNGHS 630
Cdd:COG0666  122 -TPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDN-DGETPLHLAAENGHL 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  631 ECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHG 709
Cdd:COG0666  200 EIVKLLLEA----GAdVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLAL 275

                        330
                 ....*....|....
gi 63100468  710 AKCLLRDSRGRTPI 723
Cdd:COG0666  276 LLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

289-587

9.52e-30

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 120.06 E-value: 9.52e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  289 LELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 368
Cdd:COG0666    4 LLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  369 GIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAAN 448
Cdd:COG0666   84 DDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAAN 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  449 CNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 528
Cdd:COG0666  164 GNLEIVKLLLEAGADVNARDNDGETPLHLAAENG-HLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAG 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468  529 PLDvlmetsgtdmlsDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPL 587
Cdd:COG0666  243 ADL------------NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

352-690

4.71e-29

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 118.13 E-value: 4.71e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  352 ELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADF 431
Cdd:COG0666    1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  432 NKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYnavhy 511
Cdd:COG0666   81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNG-NLEIVKLLLEAGADVNAQDNDGN----- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  512 saayghrlclqliasetpldvlmetsgtdmlsdsdnratiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAA 591
Cdd:COG0666  155 ----------------------------------------TPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAA 194

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  592 FKGHVECVDVLINQGASILVKDYvLKRTPIHAAATNGHSECLRLLIGNAEpqnAVDIQDGNGQTPLMLSVLNGHTDCVYS 671
Cdd:COG0666  195 ENGHLEIVKLLLEAGADVNAKDN-DGKTALDLAAENGNLEIVKLLLEAGA---DLNAKDKDGLTALLLAAAAGAALIVKL 270

                        330
                 ....*....|....*....
gi 63100468  672 LLNKGANVDAKDKWGRTAL 690
Cdd:COG0666  271 LLLALLLLAAALLDLLTLL 289

PHA02878

ankyrin repeat protein; Provisional

75-353

1.36e-25

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 111.90 E-value: 1.36e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    75 LTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSD--RAGRTALHHAAFsgh 152
Cdd:PHA02878   38 FIPLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRSINKCSVFYtlVAIKDAFNNRNV--- 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   153 gEMVK-LLLSRGANINAFDKKDRRAIHWAAYMgHIEVVKLLVSHGAEVTCKDK-KSYTPLHAAASSGMISVVKYLLDLGV 230
Cdd:PHA02878  115 -EIFKiILTNRYKNIQTIDLVYIDKKSKDDII-EAEITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGA 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   231 DMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK-DGKTP 309
Cdd:PHA02878  193 NVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDYDILKLLLEHGVDVNAKSYiLGLTA 272

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 63100468   310 LHMtALHGRfSRSQTIIQSGAVIDCEDKNGNTPLHIAA--RYGHEL 353
Cdd:PHA02878  273 LHS-SIKSE-RKLKLLLEYGADINSLNSYKLTPLSSAVkqYLCINI 316

PHA03100

ankyrin repeat protein; Provisional

186-400

2.76e-25

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 110.14 E-value: 2.76e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   186 IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH---VACYNGQDVV--VNELID 260
Cdd:PHA03100   15 VKNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHylsNIKYNLTDVKeiVKLLLE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   261 CGANVNQKNEKGFTPLHFAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMtAL---HGRFSRSQTIIQSGA------ 330
Cdd:PHA03100   95 YGANVNAPDNNGITPLLYAISKKSNSYSIvEYLLDNGANVNIKNSDGENLLHL-YLesnKIDLKILKLLIDKGVdinakn 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   331 ----------VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 400
Cdd:PHA03100  174 rvnyllsygvPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKT 253

PHA03100

ankyrin repeat protein; Provisional

10-270

3.03e-25

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 109.75 E-value: 3.03e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    10 PSLVQAIFN-GDPDEVRALIFKKE-DVNFQDNEKRTPLHAAAY--LGDAEIIELLILSGARVNAKDSKWLTPLHRAVASC 85
Cdd:PHA03100   73 HYLSNIKYNlTDVKEIVKLLLEYGaNVNAPDNNGITPLLYAISkkSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESN 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    86 SEEAvqillkhsadvnardknwqtplhiaaankavkcaeslvpllsnvnvsdragrtalhhaafsghgEMVKLLLSRGAN 165
Cdd:PHA03100  153 KIDL----------------------------------------------------------------KILKLLIDKGVD 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   166 INAfdkKDRraihwaaymghievVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHV 245
Cdd:PHA03100  169 INA---KNR--------------VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHI 231

                         250       260
                  ....*....|....*....|....*
gi 63100468   246 ACYNGQDVVVNELIDCGANVNQKNE 270
Cdd:PHA03100  232 AILNNNKEIFKLLLNNGPSIKTIIE 256

PHA02874

ankyrin repeat protein; Provisional

241-519

4.74e-23

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 103.50 E-value: 4.74e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   241 TPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLhFAAASTHGALCLELLVGNGADVNMkskdgktpLHMTALHGRFS 320
Cdd:PHA02874   37 TPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPL-LTAIKIGAHDIIKLLIDNGVDTSI--------LPIPCIEKDMI 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   321 RsqTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 400
Cdd:PHA02874  108 K--TILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANV 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   401 PDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAanCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 480
Cdd:PHA02874  186 KDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAI--IHNRSAIELLINNASINDQDIDGSTPLHHAIN 263

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 63100468   481 SDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRL 519
Cdd:PHA02874  264 PPCDIDIIDILLYHKADISIKDNKGENPIDTAFKYINKD 302

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

774-979

5.34e-22

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 97.72 E-value: 5.34e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  774 LLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSAD 853
Cdd:COG0666    5 LLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  854 STGKTPLMMAAENGQTNTVEMLVsSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDrnlINATNAALQTPLHVA 933
Cdd:COG0666   85 DGGNTLLHAAARNGDLEIVKLLL-EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGAD---VNAQDNDGNTPLHLA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 63100468  934 ARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALI 979
Cdd:COG0666  161 AANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLL 206

PHA02874

ankyrin repeat protein; Provisional

554-863

2.06e-21

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 98.50 E-value: 2.06e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   554 LHLAAYHGHHQALEVLVQS---LLDLDVRNSSgrTPLDLAAFKGHVECVDVLINQGASIlvkDYVLKRTP--IHAAATNG 628
Cdd:PHA02874    5 LRMCIYSGDIEAIEKIIKNkgnCINISVDETT--TPLIDAIRSGDAKIVELFIKHGADI---NHINTKIPhpLLTAIKIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   629 HSECLRLLIGNAEPQNAVDIQDGNGQTplmlsvlnghtdcVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 708
Cdd:PHA02874   80 AHDIIKLLIDNGVDTSILPIPCIEKDM-------------IKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEY 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   709 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDANpavvDNHGYTALHWACYNGHETCVELLLEQ--DVFQKIDg 786
Cdd:PHA02874  147 GADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVK----DNNGESPLHNAAEYGDYACIKLLIDHgnHIMNKCK- 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63100468   787 NAFSPLHCAVINdNEGAAEMLIDSlgASIvNATDSKGRTPLH-AAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMA 863
Cdd:PHA02874  222 NGFTPLHNAIIH-NRSAIELLINN--ASI-NDQDIDGSTPLHhAINPPCDIDIIDILLYHKADISIKDNKGENPIDTA 295

PHA02878

ankyrin repeat protein; Provisional

30-317

3.64e-21

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 98.03 E-value: 3.64e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    30 KKEDVNFQDNEKRT---------PLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLK----- 95
Cdd:PHA02878   17 LKYIEYIDHTENYStsaslipfiPLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRsinkc 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    96 -------------HSADVNA-------RDKNWQTP--LHIAAANKAVKCAESLVPLL----SNVNVSDR-AGRTALHHAA 148
Cdd:PHA02878   97 svfytlvaikdafNNRNVEIfkiiltnRYKNIQTIdlVYIDKKSKDDIIEAEITKLLlsygADINMKDRhKGNTALHYAT 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   149 FSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM-ISVVKYLLD 227
Cdd:PHA02878  177 ENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKdYDILKLLLE 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   228 LGVDMN-EPNAYGNTPLHVACYNGQdvVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDG 306
Cdd:PHA02878  257 HGVDVNaKSYILGLTALHSSIKSER--KLKLLLEYGADINSLNSYKLTPLSSAVKQYLCINIGRILISNICLLKRIKPDI 334

                         330
                  ....*....|....*
gi 63100468   307 KTPL----HMTALHG 317
Cdd:PHA02878  335 KNSEgfidNMDCITS 349

Ank_2

Ankyrin repeats (3 copies);

144-236

6.62e-21

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.25 E-value: 6.62e-21

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    144 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHgAEVTCKDKKsYTPLHAAASSGMISVVK 223
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNG-RTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    224 YLLDLGVDMNEPN 236
Cdd:pfam12796   79 LLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

177-269

9.48e-21

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 87.86 E-value: 9.48e-21

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    177 IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDlGVDMNEPNaYGNTPLHVACYNGQDVVVN 256
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    257 ELIDCGANVNQKN 269
Cdd:pfam12796   79 LLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

111-203

1.08e-20

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 87.48 E-value: 1.08e-20

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    111 LHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRgANINAFDkKDRRAIHWAAYMGHIEVVK 190
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    191 LLVSHGAEVTCKD 203
Cdd:pfam12796   79 LLLEKGADINVKD 91

PHA02876

ankyrin repeat protein; Provisional

192-679

4.97e-20

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 95.90 E-value: 4.97e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   192 LVSHGAEvTCKDKK-SYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYG-NTPLHVACY--NGQDVVVNELIDCGANVNQ 267
Cdd:PHA02876   27 LHKHGAN-QCENESiPFTAIHQALQLRQIDIVEEIIQQNPELIYITDHKcHSTLHTICIipNVMDIVISLTLDCDIILDI 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   268 KNEKGFTPLHfaaasTHGALCLELLVG--NGADVNMkSKDGKTPLHMTALHGRFSR-----SQTIIQSGAVIDCEDKNGN 340
Cdd:PHA02876  106 KYASIILNKH-----KLDEACIHILKEaiSGNDIHY-DKINESIEYMKLIKERIQQdelliAEMLLEGGADVNAKDIYCI 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   341 TPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK-----------------------------L 391
Cdd:PHA02876  180 TPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAiidnrsninkndlsllkairnedletsllL 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   392 LSSGFDIDTPDDFGRTCLH-AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAAN-CNYQCLFALVGSGASVNDLDE 469
Cdd:PHA02876  260 YDAGFSVNSIDDCKNTPLHhASQAPSLSRLVPKLLERGADVNAKNIKGETPLYLMAKNgYDTENIRTLIMLGADVNAADR 339

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   470 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGhrlclQLIASETPLDVlmetsGTDMLSDSDNRA 549
Cdd:PHA02876  340 LYITPLHQASTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRN-----NVVIINTLLDY-----GADIEALSQKIG 409

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   550 TIspLHLAAYhghhqalevlvqslldldvrnssGRTPLdlaafkghvECVDVLINQGASILVKDYVLKrTPIH-AAATNG 628
Cdd:PHA02876  410 TA--LHFALC-----------------------GTNPY---------MSVKTLIDRGANVNSKNKDLS-TPLHyACKKNC 454

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 63100468   629 HSECLRLLIGNAEPQNAVDIQDgngQTPLMLSVlnGHTDCVYSLLNKGANV 679
Cdd:PHA02876  455 KLDVIEMLLDNGADVNAINIQN---QYPLLIAL--EYHGIVNILLHYGAEL 500

PHA03095

ankyrin-like protein; Provisional

672-982

1.67e-19

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 92.78 E-value: 1.67e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   672 LLNKGANVDAKDKWGRTALHRGAVTGHEEC---VDALLQHGAKCLLRDSRGRTPIHLsaacghigvlgaLLQSATSVDAn 748
Cdd:PHA03095   33 LLAAGADVNFRGEYGKTPLHLYLHYSSEKVkdiVRLLLEAGADVNAPERCGFTPLHL------------YLYNATTLDV- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   749 pavvdnhgytalhwacynghetcVELLLEQ--DVFQKiDGNAFSPLH--CAVINDNEGAAEMLIDsLGASiVNATDSKGR 824
Cdd:PHA03095  100 -----------------------IKLLIKAgaDVNAK-DKVGRTPLHvyLSGFNINPKVIRLLLR-KGAD-VNALDLYGM 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   825 TPLHAA-AFTD-HVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNT--VEMLVSsASADLTLQDKSKNTALHLACGK 900
Cdd:PHA03095  154 TPLAVLlKSRNaNVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPRAriVRELIR-AGCDPAATDMLGNTPLHSMATG 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   901 GHETSALLI--LEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVaDCLAL 978
Cdd:PHA03095  233 SSCKRSLVLplLIAGIS---INARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNG-RAVRA 308


                  ....
gi 63100468   979 ILAT 982
Cdd:PHA03095  309 ALAK 312

Ank_2

Ankyrin repeats (3 copies);

12-104

2.49e-19

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 83.63 E-value: 2.49e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468     12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLiLSGARVNAKDSKWlTPLHRAVASCSEEAVQ 91
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLL-LEHADVNLKDNGR-TALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468     92 ILLKHSADVNARD 104
Cdd:pfam12796   79 LLLEKGADINVKD 91

PHA02875

ankyrin repeat protein; Provisional

42-266

4.22e-19

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 91.21 E-value: 4.22e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    42 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVK 121
Cdd:PHA02875    3 QVALCDAILFGELDIARRLLDIGINPNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   122 CAESLvpLLSNVNVSD---RAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE 198
Cdd:PHA02875   83 AVEEL--LDLGKFADDvfyKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKAC 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 63100468   199 VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDmnePNAYGNTP-LHVACY---NGQDVVVNELIDCGANVN 266
Cdd:PHA02875  161 LDIEDCCGCTPLIIAMAKGDIAICKMLLDSGAN---IDYFGKNGcVAALCYaieNNKIDIVRLFIKRGADCN 229

PHA03095

ankyrin-like protein; Provisional

575-846

1.09e-18

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 90.47 E-value: 1.09e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   575 DLDVRNSSGRTPLDLAAFKGHVECVDV---LINQGASILVKDyVLKRTPIHAAATNGHSE-CLRLLIGNaepqNA-VDIQ 649
Cdd:PHA03095   39 DVNFRGEYGKTPLHLYLHYSSEKVKDIvrlLLEAGADVNAPE-RCGFTPLHLYLYNATTLdVIKLLIKA----GAdVNAK 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   650 DGNGQTPL--MLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALH----RGAVTghEECVDALLQHGAKCLLRDSRGRTPI 723
Cdd:PHA03095  114 DKVGRTPLhvYLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAvllkSRNAN--VELLRLLIDAGADVYAVDDRFRSLL 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   724 HLSAACGHI--GVLGALlqsaTSVDANPAVVDNHGYTALHWACYngHETCVELLLEQDVFQKIDGNA-----FSPLHCAV 796
Cdd:PHA03095  192 HHHLQSFKPraRIVREL----IRAGCDPAATDMLGNTPLHSMAT--GSSCKRSLVLPLLIAGISINArnrygQTPLHYAA 265

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 63100468   797 INDNEGAAEMLIdSLGASIvNATDSKGRTPLHAAAFTDHVECLQLLLSQN 846
Cdd:PHA03095  266 VFNNPRACRRLI-ALGADI-NAVSSDGNTPLSLMVRNNNGRAVRAALAKN 313

Ank_2

Ankyrin repeats (3 copies);

621-716

2.10e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 80.93 E-value: 2.10e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    621 IHAAATNGHSECLRLLIgnaEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKgANVDAKDKwGRTALHRGAVTGHEE 700
Cdd:pfam12796    1 LHLAAKNGNLELVKLLL---ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLE 75

                           90
                   ....*....|....*.
gi 63100468    701 CVDALLQHGAKCLLRD 716
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

587-683

3.07e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 80.55 E-value: 3.07e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    587 LDLAAFKGHVECVDVLINQGASILVKDyVLKRTPIHAAATNGHSECLRLLIGNAEPQNavdiqDGNGQTPLMLSVLNGHT 666
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQD-KNGRTALHLAAKNGHLEIVKLLLEHADVNL-----KDNGRTALHYAARSGHL 74

                           90
                   ....*....|....*..
gi 63100468    667 DCVYSLLNKGANVDAKD 683
Cdd:pfam12796   75 EIVKLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

210-302

4.71e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 80.16 E-value: 4.71e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    210 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCgANVNQKNEkGFTPLHFAAASTHGAlCL 289
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLE-IV 77

                           90
                   ....*....|...
gi 63100468    290 ELLVGNGADVNMK 302
Cdd:pfam12796   78 KLLLEKGADINVK 90

Ank_2

Ankyrin repeats (3 copies);

45-170

5.35e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 79.77 E-value: 5.35e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468     45 LHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHsADVNARDKnwqtplhiaaankavkcae 124
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN------------------- 60

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 63100468    125 slvpllsnvnvsdraGRTALHHAAFSGHGEMVKLLLSRGANINAFD 170
Cdd:pfam12796   61 ---------------GRTALHYAARSGHLEIVKLLLEKGADINVKD 91

PHA02876

ankyrin repeat protein; Provisional

428-777

1.15e-17

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 88.20 E-value: 1.15e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   428 GADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYN 507
Cdd:PHA02876  168 GADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSK-NIDTIKAIIDNRSNINKNDLSLLK 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   508 AVHYSAAyghrlclqliasETPLdvLMETSGTDMLSDSDNRATisPLHLAAyhgHHQALEVLVQSLL----DLDVRNSSG 583
Cdd:PHA02876  247 AIRNEDL------------ETSL--LLYDAGFSVNSIDDCKNT--PLHHAS---QAPSLSRLVPKLLergaDVNAKNIKG 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   584 RTPLDLAAFKGH-VECVDVLINQGASILVKDYvLKRTPIHAAATnghseclrllignaepqnavdiqdgngqtplmlsvL 662
Cdd:PHA02876  308 ETPLYLMAKNGYdTENIRTLIMLGADVNAADR-LYITPLHQAST-----------------------------------L 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   663 NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLsAACGhigvLGALLQSA 742
Cdd:PHA02876  352 DRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHF-ALCG----TNPYMSVK 426

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 63100468   743 TSVDANPAVVDNHGY--TALHWACYNGHE-TCVELLLE 777
Cdd:PHA02876  427 TLIDRGANVNSKNKDlsTPLHYACKKNCKlDVIEMLLD 464

PHA02874

ankyrin repeat protein; Provisional

12-195

1.96e-17

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 86.17 E-value: 1.96e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQ 91
Cdd:PHA02874  128 LHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIK 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    92 ILLKHSADVNARDKNWQTPLHiaaanKAVKCAESLVPLLSN---VNVSDRAGRTALHHA-AFSGHGEMVKLLLSRGANIN 167
Cdd:PHA02874  208 LLIDHGNHIMNKCKNGFTPLH-----NAIIHNRSAIELLINnasINDQDIDGSTPLHHAiNPPCDIDIIDILLYHKADIS 282

                         170       180
                  ....*....|....*....|....*....
gi 63100468   168 AFDKKDRRAIHWA-AYMGHIEVVKLLVSH 195
Cdd:PHA02874  283 IKDNKGENPIDTAfKYINKDPVIKDIIAN 311

PHA03095

ankyrin-like protein; Provisional

389-747

2.55e-17

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 86.23 E-value: 2.55e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   389 RKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECL---NLLLNTGADFNKKDKFGRSPLH-YAAANCNYQCLFALVGSGASV 464
Cdd:PHA03095   31 RRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKdivRLLLEAGADVNAPERCGFTPLHlYLYNATTLDVIKLLIKAGADV 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   465 NDLDERGCTPLH-YAATSDTDGKCLEYLLRNDANPGIRDKqgynavhysaaYGHrlclqliaseTPLDVLMetsgtdmls 543
Cdd:PHA03095  111 NAKDKVGRTPLHvYLSGFNINPKVIRLLLRKGADVNALDL-----------YGM----------TPLAVLL--------- 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   544 dSDNRATISPLHLaayhghhqalevLVQSLLDLDVRNSSGRTPLD--LAAFKGHVECVDVLINQGASILVKDyVLKRTPI 621
Cdd:PHA03095  161 -KSRNANVELLRL------------LIDAGADVYAVDDRFRSLLHhhLQSFKPRARIVRELIRAGCDPAATD-MLGNTPL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   622 HAAATngHSECLRLLIGNaepqnavdiqdgngqtplmlsvlnghtdcvysLLNKGANVDAKDKWGRTALHRGAVTGHEEC 701
Cdd:PHA03095  227 HSMAT--GSSCKRSLVLP--------------------------------LLIAGISINARNRYGQTPLHYAAVFNNPRA 272

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 63100468   702 VDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDA 747
Cdd:PHA03095  273 CRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAET 318

PHA02876

ankyrin repeat protein; Provisional

672-964

2.59e-17

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 87.04 E-value: 2.59e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   672 LLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDANPAV 751
Cdd:PHA02876  164 LLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLS 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   752 -------------------------VDNHGYTALHWACYNGH-ETCVELLLEQ--DVFQK-IDGNafSPLHCAVINDNEG 802
Cdd:PHA02876  244 llkairnedletslllydagfsvnsIDDCKNTPLHHASQAPSlSRLVPKLLERgaDVNAKnIKGE--TPLYLMAKNGYDT 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   803 AAEMLIDSLGASiVNATDSKGRTPLHAAAFTD-HVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSAsA 881
Cdd:PHA02876  322 ENIRTLIMLGAD-VNAADRLYITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYG-A 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   882 DLTLQDKSKNTALHLA-CGKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTM-VVQELLGKGASVLAVDENG 959
Cdd:PHA02876  400 DIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGAN---VNSKNKDLSTPLHYACKKNCKLdVIEMLLDNGADVNAINIQN 476


                  ....*
gi 63100468   960 YTPAL 964
Cdd:PHA02876  477 QYPLL 481

PHA02878

ankyrin repeat protein; Provisional

24-195

5.48e-16

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 82.24 E-value: 5.48e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    24 VRALIFKKEDVNFQDNEK-RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNA 102
Cdd:PHA02878  150 TKLLLSYGADINMKDRHKgNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDA 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   103 RDKNWQTPLHIAAAnkAVKCAESLVPLL---SNVNV-SDRAGRTALHHAAFSghGEMVKLLLSRGANINAFDKKDRRAIH 178
Cdd:PHA02878  230 RDKCGNTPLHISVG--YCKDYDILKLLLehgVDVNAkSYILGLTALHSSIKS--ERKLKLLLEYGADINSLNSYKLTPLS 305

                         170
                  ....*....|....*....
gi 63100468   179 WAA--YMGhIEVVKLLVSH 195
Cdd:PHA02878  306 SAVkqYLC-INIGRILISN 323

Ank_2

Ankyrin repeats (3 copies);

657-780

8.70e-16

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 73.61 E-value: 8.70e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    657 LMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHgakcllrdsrgrtpihlsaacghigvlg 736
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH---------------------------- 52

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 63100468    737 allqsatsVDANpavVDNHGYTALHWACYNGHETCVELLLEQDV 780
Cdd:pfam12796   53 --------ADVN---LKDNGRTALHYAARSGHLEIVKLLLEKGA 85

Ank_2

Ankyrin repeats (3 copies);

554-647

9.13e-16

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 73.61 E-value: 9.13e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    554 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGAsilVKDYVLKRTPIHAAATNGHSECL 633
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD---VNLKDNGRTALHYAARSGHLEIV 77

                           90
                   ....*....|....
gi 63100468    634 RLLIGNAEPQNAVD 647
Cdd:pfam12796   78 KLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

827-920

1.02e-15

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 73.23 E-value: 1.02e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    827 LHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKsknTALHLACGKGHETSA 906
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKDNGR---TALHYAARSGHLEIV 77

                           90
                   ....*....|....
gi 63100468    907 LLILEKITDRNLIN 920
Cdd:pfam12796   78 KLLLEKGADINVKD 91

PHA02876

ankyrin repeat protein; Provisional

18-220

1.32e-15

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 81.65 E-value: 1.32e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    18 NG-DPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLG-DAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLK 95
Cdd:PHA02876  317 NGyDTENIRTLIMLGADVNAADRLYITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLD 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    96 HSADVNARDKNWQTPLHIA-AANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSG-HGEMVKLLLSRGANINAFDKKD 173
Cdd:PHA02876  397 YGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAINIQN 476

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 63100468   174 RRAIHWAayMGHIEVVKLLVSHGAEVtcKDKKSytpLHAAASSGMIS 220
Cdd:PHA02876  477 QYPLLIA--LEYHGIVNILLHYGAEL--RDSRV---LHKSLNDNMFS 516

PHA02798

ankyrin-like protein; Provisional

55-310

1.49e-15

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 80.65 E-value: 1.49e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    55 EIIELLILSGARVNAKDSKWLTPLHRAVASCSE-----EAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPL 129
Cdd:PHA02798   52 DIVKLFINLGANVNGLDNEYSTPLCTILSNIKDykhmlDIVKILIENGADINKKNSDGETPLYCLLSNGYINNLEILLFM 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   130 LSN---VNVSDRAGRTALHHAAFSGHG---EMVKLLLSRGANINAFDkkdrraiHWAAYmghievvkllvshgAEVTCKD 203
Cdd:PHA02798  132 IENgadTTLLDKDGFTMLQVYLQSNHHidiEIIKLLLEKGVDINTHN-------NKEKY--------------DTLHCYF 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   204 KKSYTPLHAaassgmiSVVKYLLDLGVDMNEPNAYGNTP----LHVACYNGQDVVVN--ELIDCGANVNQKNEKGFTPLH 277
Cdd:PHA02798  191 KYNIDRIDA-------DILKLFVDNGFIINKENKSHKKKfmeyLNSLLYDNKRFKKNilDFIFSYIDINQVDELGFNPLY 263

                         250       260       270
                  ....*....|....*....|....*....|...
gi 63100468   278 FAAASTHGALClELLVGNGADVNMKSKDGKTPL 310
Cdd:PHA02798  264 YSVSHNNRKIF-EYLLQLGGDINIITELGNTCL 295

PLN03192

Voltage-dependent potassium channel; Provisional

531-710

1.66e-15

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 81.45 E-value: 1.66e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   531 DVLMETSGTDmlsdsDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 610
Cdd:PLN03192  511 DLLGDNGGEH-----DDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVH 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   611 VKDyVLKRTPIHAAATNGHSECLRLLIGNA---EPQNAVDIqdgngqtpLMLSVLNGHTDCVYSLLNKGANVDAKDKWGR 687
Cdd:PLN03192  586 IRD-ANGNTALWNAISAKHHKIFRILYHFAsisDPHAAGDL--------LCTAAKRNDLTAMKELLKQGLNVDSEDHQGA 656

                         170       180
                  ....*....|....*....|...
gi 63100468   688 TALHRGAVTGHEECVDALLQHGA 710
Cdd:PLN03192  657 TALQVAMAEDHVDMVRLLIMNGA 679

PHA03100

ankyrin repeat protein; Provisional

772-958

3.15e-15

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 79.32 E-value: 3.15e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   772 VELLLEQ--DVFQKIDGNaFSPLH-----CAVINDNEGAAEMLIdSLGASIvNATDSKGRTPLHAAAFT--DHVECLQLL 842
Cdd:PHA03100   51 VKILLDNgaDINSSTKNN-STPLHylsniKYNLTDVKEIVKLLL-EYGANV-NAPDNNGITPLLYAISKksNSYSIVEYL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   843 LSQNAQVNSADSTGKTPLMMAAENG------------------QTNTVEMLVSSASaDLTLQDKSKNTALHLACGKGHET 904
Cdd:PHA03100  128 LDNGANVNIKNSDGENLLHLYLESNkidlkilkllidkgvdinAKNRVNYLLSYGV-PINIKDVYGFTPLHYAVYNNNPE 206

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 63100468   905 SALLILEKITDRNLINATNaalQTPLHVAARNGLTMVVQELLGKGASVLAVDEN 958
Cdd:PHA03100  207 FVKYLLDLGANPNLVNKYG---DTPLHIAILNNNKEIFKLLLNNGPSIKTIIET 257

PHA02878

ankyrin repeat protein; Provisional

209-523

5.50e-15

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 78.77 E-value: 5.50e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   209 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYN----GQDVVVNELIDCGA--------------NVN---- 266
Cdd:PHA02878   40 PLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEpnklGMKEMIRSINKCSVfytlvaikdafnnrNVEifki 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   267 -----QKNEKGFTPLHFAAASTHGAL---CLELLVGNGADVNMKSKD-GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDK 337
Cdd:PHA02878  120 iltnrYKNIQTIDLVYIDKKSKDDIIeaeITKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNIPDK 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   338 NGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFS-DCCRKLLSSGFDIDTpddfgrtclhaaaagg 416
Cdd:PHA02878  200 TNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDyDILKLLLEHGVDVNA---------------- 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   417 nleclnlllntgadfnKKDKFGRSPLHYAAAncNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYL----- 491
Cdd:PHA02878  264 ----------------KSYILGLTALHSSIK--SERKLKLLLEYGADINSLNSYKLTPLSSAVKQYLCINIGRILisnic 325

                         330       340       350
                  ....*....|....*....|....*....|..
gi 63100468   492 LRNDANPGIRDKQGYnAVHYSAAYGHRLCLQL 523
Cdd:PHA02878  326 LLKRIKPDIKNSEGF-IDNMDCITSNKRLNQI 356

PHA03095

ankyrin-like protein; Provisional

17-168

6.49e-15

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 78.53 E-value: 6.49e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    17 FNGDPDEVRALIFKKEDVNFQDNEKRTPLHaaAYLG----DAEIIELLILSGARVNAKDSKWLTPLH------RAVASCS 86
Cdd:PHA03095  128 FNINPKVIRLLLRKGADVNALDLYGMTPLA--VLLKsrnaNVELLRLLIDAGADVYAVDDRFRSLLHhhlqsfKPRARIV 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    87 EEavqiLLKHSADVNARDKNWQTPLHIAAANKAvkCAESLV-PLLSN---VNVSDRAGRTALHHAAFSGHGEMVKLLLSR 162
Cdd:PHA03095  206 RE----LIRAGCDPAATDMLGNTPLHSMATGSS--CKRSLVlPLLIAgisINARNRYGQTPLHYAAVFNNPRACRRLIAL 279


                  ....*.
gi 63100468   163 GANINA 168
Cdd:PHA03095  280 GADINA 285

Ank_2

Ankyrin repeats (3 copies);

760-853

6.99e-15

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 70.92 E-value: 6.99e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    760 LHWACYNGHETCVELLLEQDV-FQKIDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNatdsKGRTPLHAAAFTDHVEC 838
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGAdANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKD----NGRTALHYAARSGHLEI 76

                           90
                   ....*....|....*
gi 63100468    839 LQLLLSQNAQVNSAD 853
Cdd:pfam12796   77 VKLLLEKGADINVKD 91

PHA02874

ankyrin repeat protein; Provisional

310-647

1.07e-14

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 77.70 E-value: 1.07e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   310 LHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCC 388
Cdd:PHA02874    5 LRMCIYSGDIEAIEKIIKNkGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDII 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   389 RKLLSSGFDI------DTPDDFGRTCLHaaaaggnleclnlllnTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGA 462
Cdd:PHA02874   85 KLLIDNGVDTsilpipCIEKDMIKTILD----------------CGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGA 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   463 SVNDLDERGCTPLHYAATSDTdGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIAsetpldvlmeTSGTDML 542
Cdd:PHA02874  149 DVNIEDDNGCYPIHIAIKHNF-FDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLI----------DHGNHIM 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   543 SDSDNRATisPLHLAAYHgHHQALEVLVQSlLDLDVRNSSGRTPLDLA-AFKGHVECVDVLINQGASILVKDYVlKRTPI 621
Cdd:PHA02874  218 NKCKNGFT--PLHNAIIH-NRSAIELLINN-ASINDQDIDGSTPLHHAiNPPCDIDIIDILLYHKADISIKDNK-GENPI 292

                         330       340
                  ....*....|....*....|....*..
gi 63100468   622 HAAATN-GHSECLRLLIGNAEPQNAVD 647
Cdd:PHA02874  293 DTAFKYiNKDPVIKDIIANAVLIKEAD 319

PHA03100

ankyrin repeat protein; Provisional

427-684

1.61e-14

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 77.01 E-value: 1.61e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   427 TGADFNKKDKFGRSPLHYAA-----ANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSD-TDGKCLEYLLRNDANPGI 500
Cdd:PHA03100   57 NGADINSSTKNNSTPLHYLSnikynLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKKsNSYSIVEYLLDNGANVNI 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   501 RDKQGYNAVHYSAAYGHRlclqliasETPLDVLMETSGTDMlsDSDNRatisplhlaayhghhqaLEVLVQSLLDLDVRN 580
Cdd:PHA03100  137 KNSDGENLLHLYLESNKI--------DLKILKLLIDKGVDI--NAKNR-----------------VNYLLSYGVPINIKD 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   581 SSGRTPLDLAAFKGHVECVDVLINQGASIlvkdyvlkrtpihaaatnghseclrllignaepqNAVDIqdgNGQTPLMLS 660
Cdd:PHA03100  190 VYGFTPLHYAVYNNNPEFVKYLLDLGANP----------------------------------NLVNK---YGDTPLHIA 232

                         250       260
                  ....*....|....*....|....
gi 63100468   661 VLNGHTDCVYSLLNKGANVDAKDK 684
Cdd:PHA03100  233 ILNNNKEIFKLLLNNGPSIKTIIE 256

PLN03192

Voltage-dependent potassium channel; Provisional

30-201

1.80e-14

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 77.99 E-value: 1.80e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    30 KKEDVNFQDNEKRTPLHAAAYL------GDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNAR 103
Cdd:PLN03192  508 NVGDLLGDNGGEHDDPNMASNLltvastGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIR 587

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   104 DKNWQTPLHIAAANKAVKCAESLVPLLSnvnVSD-RAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAY 182
Cdd:PLN03192  588 DANGNTALWNAISAKHHKIFRILYHFAS---ISDpHAAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMA 664

                         170
                  ....*....|....*....
gi 63100468   183 MGHIEVVKLLVSHGAEVTC 201
Cdd:PLN03192  665 EDHVDMVRLLIMNGADVDK 683

PHA02878

ankyrin repeat protein; Provisional

309-603

7.14e-14

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 75.30 E-value: 7.14e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   309 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITS----GADTAKRGIHGMFplHLAALSGF 384
Cdd:PHA02878   40 PLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRSinkcSVFYTLVAIKDAF--NNRNVEIF 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   385 sdccRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDK-FGRSPLHYAAANCNYQCLFALVGSGAS 463
Cdd:PHA02878  118 ----KIILTNRYKNIQTIDLVYIDKKSKDDIIEAEITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGAN 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   464 VNDLDERGCTPLHYaATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYghrlclqlIASETPLDVLMEtSGTDMLS 543
Cdd:PHA02878  194 VNIPDKTNNSPLHH-AVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGY--------CKDYDILKLLLE-HGVDVNA 263

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 63100468   544 DSDNRAtISPLHLAAYhgHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGH-VECVDVLI 603
Cdd:PHA02878  264 KSYILG-LTALHSSIK--SERKLKLLLEYGADINSLNSYKLTPLSSAVKQYLcINIGRILI 321

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

74-259

9.54e-14

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 75.43 E-value: 9.54e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   74 WLTPLHRAVASCSEEAVQILLK-HSADVNARDKNWQTPLHIAAANKAVKCAESL---VPLLSNVNV-SD-RAGRTALHHA 147
Cdd:cd22192   17 SESPLLLAAKENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLmeaAPELVNEPMtSDlYQGETALHIA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  148 AFSGHGEMVKLLLSRGANIN-------AFDKKDRRAIHW-------AAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 213
Cdd:cd22192   97 VVNQNLNLVRELIARGADVVspratgtFFRPGPKNLIYYgehplsfAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHIL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468  214 ASSGMISVVKYLLDLGVDMNE----------PNAYGNTPLHVACYNGQDVVVNELI 259
Cdd:cd22192  177 VLQPNKTFACQMYDLILSYDKeddlqpldlvPNNQGLTPFKLAAKEGNIVMFQHLV 232

PHA03095

ankyrin-like protein; Provisional

18-168

1.78e-13

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 73.91 E-value: 1.78e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    18 NGDPDEVRALIFKKEDVNFQDNEKRTPLH--AAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQI--L 93
Cdd:PHA03095  164 NANVELLRLLIDAGADVYAVDDRFRSLLHhhLQSFKPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVlpL 243

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    94 LKHSADVNARDKNWQTPLHIAAA-NKAVKCAEsLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 168
Cdd:PHA03095  244 LIAGISINARNRYGQTPLHYAAVfNNPRACRR-LIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAET 318

PHA03100

ankyrin repeat protein; Provisional

667-879

4.68e-13

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 72.39 E-value: 4.68e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   667 DCVYSLLNKGANVDAKDKWGRTALHRGAVTGHE-----ECVDALLQHGAKCLLRDSRGRTPIHLSAAC--GHIGVLGALL 739
Cdd:PHA03100   49 DVVKILLDNGADINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   740 QSAtsvdANPAVVDNHGYTALHWA---CYNGHETcVELLLEQdvfqKIDGNAfsplhCAVINdnegaaeMLIdSLGASIv 816
Cdd:PHA03100  129 DNG----ANVNIKNSDGENLLHLYlesNKIDLKI-LKLLIDK----GVDINA-----KNRVN-------YLL-SYGVPI- 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468   817 NATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSA 879
Cdd:PHA03100  186 NIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNG 248

Ank_2

Ankyrin repeats (3 copies);

860-956

5.66e-13

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.52 E-value: 5.66e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    860 LMMAAENGQTNTVEMLVSSaSADLTLQDKSKNTALHLACGKGHETSALLILEKItDRNLINATNaalqTPLHVAARNGLT 939
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLEN-GADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA-DVNLKDNGR----TALHYAARSGHL 74

                           90
                   ....*....|....*..
gi 63100468    940 MVVQELLGKGASVLAVD 956
Cdd:pfam12796   75 EIVKLLLEKGADINVKD 91

PHA02798

ankyrin-like protein; Provisional

186-412

8.96e-13

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 71.79 E-value: 8.96e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   186 IEVVKLLVSHGAEVTCKDKKSYTPLHAAASS-----GMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGqdvVVNEL-- 258
Cdd:PHA02798   51 TDIVKLFINLGANVNGLDNEYSTPLCTILSNikdykHMLDIVKILIENGADINKKNSDGETPLYCLLSNG---YINNLei 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   259 ----IDCGANVNQKNEKGFTPLHFAAASTHGAL--CLELLVGNGADVNMKSKDGKtplhMTALHGRFSRS---------Q 323
Cdd:PHA02798  128 llfmIENGADTTLLDKDGFTMLQVYLQSNHHIDieIIKLLLEKGVDINTHNNKEK----YDTLHCYFKYNidridadilK 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   324 TIIQSGAVIDCEDKNGNTPLhiaARYGHELLINT---------LITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS 394
Cdd:PHA02798  204 LFVDNGFIINKENKSHKKKF---MEYLNSLLYDNkrfkknildFIFSYIDINQVDELGFNPLYYSVSHNNRKIFEYLLQL 280

                         250
                  ....*....|....*...
gi 63100468   395 GFDIDTPDDFGRTCLHAA 412
Cdd:PHA02798  281 GGDINIITELGNTCLFTA 298

Ank_2

Ankyrin repeats (3 copies);

310-402

9.12e-13

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.14 E-value: 9.12e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    310 LHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAdtAKRGIHGMFPLHLAALSGFSDCCR 389
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    390 KLLSSGFDIDTPD 402
Cdd:pfam12796   79 LLLEKGADINVKD 91

PHA02874

ankyrin repeat protein; Provisional

537-723

9.67e-13

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 71.53 E-value: 9.67e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   537 SGTDMlsDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYVL 616
Cdd:PHA02874  113 CGIDV--NIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   617 KrTPIHAAATNGHSECLRLLIGNAepqNAVDIQDGNGQTPLMLSVLngHTDCVYSLLNKGANVDAKDKWGRTALHRG-AV 695
Cdd:PHA02874  191 E-SPLHNAAEYGDYACIKLLIDHG---NHIMNKCKNGFTPLHNAII--HNRSAIELLINNASINDQDIDGSTPLHHAiNP 264

                         170       180
                  ....*....|....*....|....*...
gi 63100468   696 TGHEECVDALLQHGAKCLLRDSRGRTPI 723
Cdd:PHA02874  265 PCDIDIIDILLYHKADISIKDNKGENPI 292

PHA02875

ankyrin repeat protein; Provisional

213-397

1.23e-12

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 71.18 E-value: 1.23e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   213 AASSGMISVVKYLLDLGVDMN--------------------------EPNAYGN-------TPLHVACYNGQDVVVNELI 259
Cdd:PHA02875    9 AILFGELDIARRLLDIGINPNfeiydgispiklamkfrdseaikllmKHGAIPDvkypdieSELHDAVEEGDVKAVEELL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   260 DCGANVNQK-NEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 338
Cdd:PHA02875   89 DLGKFADDVfYKDGMTPLHLATILKKLDI-MKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCC 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   339 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFS-DCCRKLLSSGFD 397
Cdd:PHA02875  168 GCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIENNKiDIVRLFIKRGAD 227

Ank_2

Ankyrin repeats (3 copies);

376-468

2.91e-12

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 63.60 E-value: 2.91e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    376 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTgADFNKKDKfGRSPLHYAAANCNYQCLF 455
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 63100468    456 ALVGSGASVNDLD 468
Cdd:pfam12796   79 LLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

243-336

6.22e-12

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 62.44 E-value: 6.22e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    243 LHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLvgNGADVNMKSkDGKTPLHMTALHGRFSRS 322
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL--EHADVNLKD-NGRTALHYAARSGHLEIV 77

                           90
                   ....*....|....
gi 63100468    323 QTIIQSGAVIDCED 336
Cdd:pfam12796   78 KLLLEKGADINVKD 91

PHA02878

ankyrin repeat protein; Provisional

690-962

6.32e-12

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 69.14 E-value: 6.32e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   690 LHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLsaACGHIGVLGA--LLQSATSVDANpavvdnHGYTALHWACYNG 767
Cdd:PHA02878   41 LHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHI--ICKEPNKLGMkeMIRSINKCSVF------YTLVAIKDAFNNR 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   768 HETCVELLLeQDVFQKIDGNAFSPLhCAVINDNEGAAEM--LIDSLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQ 845
Cdd:PHA02878  113 NVEIFKIIL-TNRYKNIQTIDLVYI-DKKSKDDIIEAEItkLLLSYGADINMKDRHKGNTALHYATENKDQRLTELLLSY 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   846 NAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSAsADLTLQDKSKNTALHLACGKGHETSAL-LILEKITDrnlINATNA 924
Cdd:PHA02878  191 GANVNIPDKTNNSPLHHAVKHYNKPIVHILLENG-ASTDARDKCGNTPLHISVGYCKDYDILkLLLEHGVD---VNAKSY 266

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 63100468   925 ALQ-TPLHVAARNglTMVVQELLGKGASVLAVDENGYTP 962
Cdd:PHA02878  267 ILGlTALHSSIKS--ERKLKLLLEYGADINSLNSYKLTP 303

Ank_4

Ankyrin repeats (many copies);

140-193

9.21e-12

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 60.75 E-value: 9.21e-12

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    140 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 193
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_2

Ankyrin repeats (3 copies);

276-364

1.40e-11

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 61.67 E-value: 1.40e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    276 LHFAAASTHgALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSgAVIDCEDkNGNTPLHIAARYGHELLI 355
Cdd:pfam12796    1 LHLAAKNGN-LELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIV 77


                   ....*....
gi 63100468    356 NTLITSGAD 364
Cdd:pfam12796   78 KLLLEKGAD 86

PLN03192

Voltage-dependent potassium channel; Provisional

629-838

1.82e-11

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 68.36 E-value: 1.82e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   629 HSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 708
Cdd:PLN03192  501 HKELHDLNVGDLLGDNGGEHDDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKH 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   709 GAKCLLRDSRGRTPIHLSAACGH-------------------------------IGVLGALLQSATSVDANpavvDNHGY 757
Cdd:PLN03192  581 ACNVHIRDANGNTALWNAISAKHhkifrilyhfasisdphaagdllctaakrndLTAMKELLKQGLNVDSE----DHQGA 656

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   758 TALHWACYNGHETCVELLLEQ--DVFQKIDGNAFSPLHC-AVINDNE-GAAEMLIDSLGASIVNATDSKGRTPLHAAAFT 833
Cdd:PLN03192  657 TALQVAMAEDHVDMVRLLIMNgaDVDKANTDDDFSPTELrELLQKRElGHSITIVDSVPADEPDLGRDGGSRPGRLQGTS 736


                  ....*
gi 63100468   834 DHVEC 838
Cdd:PLN03192  737 SDNQC 741

PHA02878

ankyrin repeat protein; Provisional

546-796

2.07e-11

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 67.60 E-value: 2.07e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   546 DNRATiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSsgRTPLDLAAFKGHVECVD-VLINQGASILVKDYVLKRTPIHAA 624
Cdd:PHA02878   67 DHRDL-TPLHIICKEPNKLGMKEMIRSINKCSVFYT--LVAIKDAFNNRNVEIFKiILTNRYKNIQTIDLVYIDKKSKDD 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   625 ATNghSECLRLLIGNAEPQNAVDIQDGNgqTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDA 704
Cdd:PHA02878  144 IIE--AEITKLLLSYGADINMKDRHKGN--TALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHI 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   705 LLQHGAKCLLRDSRGRTPIHLSAA-CGHIGVLGALLQSATSVDANPAVVdnhGYTALHWACYNghETCVELLLE--QDVf 781
Cdd:PHA02878  220 LLENGASTDARDKCGNTPLHISVGyCKDYDILKLLLEHGVDVNAKSYIL---GLTALHSSIKS--ERKLKLLLEygADI- 293

                         250
                  ....*....|....*
gi 63100468   782 QKIDGNAFSPLHCAV 796
Cdd:PHA02878  294 NSLNSYKLTPLSSAV 308

PHA02989

ankyrin repeat protein; Provisional

55-327

2.36e-11

ankyrin repeat protein; Provisional

Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 67.46 E-value: 2.36e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    55 EIIELLILSGARVNAKdSKWLTPL-----HRAVASCS-EEAVQILLKHSADVNARDKNWQTPlhiaaankavkcaesLVP 128
Cdd:PHA02989   51 KIVKLLIDNGADVNYK-GYIETPLcavlrNREITSNKiKKIVKLLLKFGADINLKTFNGVSP---------------IVC 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   129 LLSNVNVSDRagrtalhhaafsghgEMVKLLLSRGANINafDKKDRRA-----IHWAAYMGHIEVVKLLVSHGaeVTCKD 203
Cdd:PHA02989  115 FIYNSNINNC---------------DMLRFLLSKGINVN--DVKNSRGynllhMYLESFSVKKDVIKILLSFG--VNLFE 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   204 KKSY---TPLHAAASSGM----ISVVKYLLDLGVDMNEPNAYGNTPL------HVACYNGQDVVVNeLIDCGANVNQKNE 270
Cdd:PHA02989  176 KTSLyglTPMNIYLRNDIdvisIKVIKYLIKKGVNIETNNNGSESVLesfldnNKILSKKEFKVLN-FILKYIKINKKDK 254

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 63100468   271 KGFTPLHFAA-ASTHGALCLELLVGNgaDVNMKSKDGKTPLHMTALHGRFSRSQTIIQ 327
Cdd:PHA02989  255 KGFNPLLISAkVDNYEAFNYLLKLGD--DIYNVSKDGDTVLTYAIKHGNIDMLNRILQ 310

Ank_4

Ankyrin repeats (many copies);

174-226

4.67e-11

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 58.83 E-value: 4.67e-11

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 63100468    174 RRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLL 226
Cdd:pfam13637    2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_4

Ankyrin repeats (many copies);

552-603

1.62e-10

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 57.28 E-value: 1.62e-10

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 63100468    552 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI 603
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PHA03100

ankyrin repeat protein; Provisional

569-747

3.70e-10

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 63.15 E-value: 3.70e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   569 LVQSLLD----LDVRNSSGRTPLDLAAFKGHV-----ECVDVLINQGASILVKDYVlKRTPIHAAATN--GHSECLRLLI 637
Cdd:PHA03100   50 VVKILLDngadINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLLEYGANVNAPDNN-GITPLLYAISKksNSYSIVEYLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   638 GNAEPQNAVDiqdGNGQTPLMLSVLNGHTDC------------------VYSLLNKGANVDAKDKWGRTALHRGAVTGHE 699
Cdd:PHA03100  129 DNGANVNIKN---SDGENLLHLYLESNKIDLkilkllidkgvdinaknrVNYLLSYGVPINIKDVYGFTPLHYAVYNNNP 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 63100468   700 ECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDA 747
Cdd:PHA03100  206 EFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKT 253

PHA02946

ankyin-like protein; Provisional

49-276

4.87e-10

ankyin-like protein; Provisional

Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 63.15 E-value: 4.87e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    49 AYLG----DAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAAnkavkcae 124
Cdd:PHA02946   43 AYCGikglDERFVEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSG-------- 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   125 slvpllSNVNVSDRagrtalhhaafsghgemVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK 204
Cdd:PHA02946  115 ------TDDEVIER-----------------INLLVQYGAKINNSVDEEGCGPLLACTDPSERVFKKIMSIGFEARIVDK 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 63100468   205 --KSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNG-QDVVVNELIDCGANVNQKNEKGFTPL 276
Cdd:PHA02946  172 fgKNHIHRHLMSDNPKASTISWMMKLGISPSKPDHDGNTPLHIVCSKTvKNVDIINLLLPSTDVNKQNKFGDSPL 246

Ank_4

Ankyrin repeats (many copies);

207-251

4.98e-10

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 56.13 E-value: 4.98e-10

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 63100468    207 YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQ 251
Cdd:pfam13637    2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGN 46

Ank_2

Ankyrin repeats (3 copies);

442-526

5.36e-10

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 57.05 E-value: 5.36e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    442 LHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDgKCLEYLLRNdANPGIRDkQGYNAVHYSAAYGHRLCL 521
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHL-EIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIV 77


                   ....*
gi 63100468    522 QLIAS 526
Cdd:pfam12796   78 KLLLE 82

PHA02875

ankyrin repeat protein; Provisional

583-824

5.76e-10

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 62.70 E-value: 5.76e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   583 GRTPLDLAAFKGHVECVDVLINQGASILVKdYVLKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNgqTPLMLSVL 662
Cdd:PHA02875   35 GISPIKLAMKFRDSEAIKLLMKHGAIPDVK-YPDIESELHDAVEEGDVKAVEELLDLGKFADDVFYKDGM--TPLHLATI 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   663 NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 742
Cdd:PHA02875  112 LKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSG 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   743 tsvdANPAVVDNHG-YTALHWACYNGHETCVELLLEQ----DVFQKIDGNAFSPLHCAV---INDNEGAAEMLIDSLGAS 814
Cdd:PHA02875  192 ----ANIDYFGKNGcVAALCYAIENNKIDIVRLFIKRgadcNIMFMIEGEECTILDMICnmcTNLESEAIDALIADIAIR 267

                         250
                  ....*....|
gi 63100468   815 IVNATDSKGR 824
Cdd:PHA02875  268 IHKKTIRRDE 277

PHA02878

ankyrin repeat protein; Provisional

242-535

6.86e-10

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 62.59 E-value: 6.86e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   242 PLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLvgngadvNMKSKDgKTPLHMTALHGRFSR 321
Cdd:PHA02878   40 PLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMI-------RSINKC-SVFYTLVAIKDAFNN 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   322 SQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITsgadtakrgihgmfplhlaalsgfsdccRKLLSSGFDIDTP 401
Cdd:PHA02878  112 RNVEIFKIILTNRYKNIQTIDLVYIDKKSKDDIIEAEIT----------------------------KLLLSYGADINMK 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   402 D-DFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAAT 480
Cdd:PHA02878  164 DrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVG 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468   481 SDTDGKCLEYLLRNDANPGIRDK-QGYNAVHYSaayghrlclqlIASETPLDVLME 535
Cdd:PHA02878  244 YCKDYDILKLLLEHGVDVNAKSYiLGLTALHSS-----------IKSERKLKLLLE 288

PHA02875

ankyrin repeat protein; Provisional

254-500

7.17e-10

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 62.32 E-value: 7.17e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   254 VVNELIDCGANVNQKNEKGFTPLHFAAaSTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI- 332
Cdd:PHA02875   17 IARRLLDIGINPNFEIYDGISPIKLAM-KFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKFAd 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   333 DCEDKNGNTPLHiaaryghellintlitsgadtakrgihgmfplhLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAA 412
Cdd:PHA02875   96 DVFYKDGMTPLH---------------------------------LATILKKLDIMKLLIARGADPDIPNTDKFSPLHLA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   413 AAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLL 492
Cdd:PHA02875  143 VMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIENNKIDIVRLFI 222


                  ....*...
gi 63100468   493 RNDANPGI 500
Cdd:PHA02875  223 KRGADCNI 230

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

585-725

7.62e-10

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 62.72 E-value: 7.62e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  585 TPLDLAAFKGHVECVDVLINQGASILVKDYVLKRTPIHAAATNGHSECLRLLIGNA-----EPQNAVDIQdgnGQTPLML 659
Cdd:cd22192   19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelvnEPMTSDLYQ---GETALHI 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  660 SVLNGHTDCVYSLLNKGANV--------------DAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL 725
Cdd:cd22192   96 AVVNQNLNLVRELIARGADVvspratgtffrpgpKNLIYYGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175

PLN03192

Voltage-dependent potassium channel; Provisional

147-305

1.02e-09

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 62.58 E-value: 1.02e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   147 AAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLL 226
Cdd:PLN03192  532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILY 611

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468   227 DLGvDMNEPNAYGNTpLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKD 305
Cdd:PLN03192  612 HFA-SISDPHAAGDL-LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDM-VRLLIMNGADVDKANTD 687

Ank_2

Ankyrin repeats (3 copies);

475-580

1.57e-09

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 55.89 E-value: 1.57e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    475 LHYAATSDtDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDvlMETSGTdmlsdsdnratiSPL 554
Cdd:pfam12796    1 LHLAAKNG-NLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN--LKDNGR------------TAL 65

                           90       100
                   ....*....|....*....|....*.
gi 63100468    555 HLAAYHGHHQALEVLVQSLLDLDVRN 580
Cdd:pfam12796   66 HYAARSGHLEIVKLLLEKGADINVKD 91

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

771-948

2.08e-09

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 61.57 E-value: 2.08e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  771 CVELLLEQ---DVFQKiDGNAFSPLHCAVINDNEGAAEMLIDSLGASIVNATDS---KGRTPLHAAAFTDHVECLQLLLS 844
Cdd:cd22192   32 AIKKLLKCpscDLFQR-GALGETALHVAALYDNLEAAVVLMEAAPELVNEPMTSdlyQGETALHIAVVNQNLNLVRELIA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  845 QNAQVNSADST--------------GKTPLMMAAENGQTNTVEMLVsSASADLTLQDKSKNTALHLACGKGHETSA---- 906
Cdd:cd22192  111 RGADVVSPRATgtffrpgpknliyyGEHPLSFAACVGNEEIVRLLI-EHGADIRAQDSLGNTVLHILVLQPNKTFAcqmy 189

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 63100468  907 --LLILEK-ITDRNLINATNAALQTPLHVAARNGLTMVVQELLGK 948
Cdd:cd22192  190 dlILSYDKeDDLQPLDLVPNNQGLTPFKLAAKEGNIVMFQHLVQK 234

PHA02859

ankyrin repeat protein; Provisional

72-250

2.54e-09

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 58.29 E-value: 2.54e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    72 SKWLTPLHRAVASCSEEAVQillKHSADVNARDKNWQTPLHIAAANKAV--KCAESLVPLLSNVNVSDRA-GRTALHHAA 148
Cdd:PHA02859   19 YRYCNPLFYYVEKDDIEGVK---KWIKFVNDCNDLYETPIFSCLEKDKVnvEILKFLIENGADVNFKTRDnNLSALHHYL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   149 FSGHG---EMVKLLLSRGANINAFDKKDRRAIHwaAYMGH----IEVVKLLVSHGAEVTCKDKK------SYTPLHAAAS 215
Cdd:PHA02859   96 SFNKNvepEILKILIDSGSSITEEDEDGKNLLH--MYMCNfnvrINVIKLLIDSGVSFLNKDFDnnnilySYILFHSDKK 173

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 63100468   216 sgmisVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 250
Cdd:PHA02859  174 -----IFDFLTSLGIDINETNKSGYNCYDLIKFRN 203

PLN03192

Voltage-dependent potassium channel; Provisional

183-374

2.88e-09

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 61.42 E-value: 2.88e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   183 MGHIEVVKLLVSHGAEVTckDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 262
Cdd:PLN03192  504 LHDLNVGDLLGDNGGEHD--DPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHA 581

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   263 ANVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSkdGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTP 342
Cdd:PLN03192  582 CNVHIRDANGNTALWNAISAKHHKI-FRILYHFASISDPHA--AGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATA 658

                         170       180       190
                  ....*....|....*....|....*....|..
gi 63100468   343 LHIAARYGHELLINTLITSGADTAKRGIHGMF 374
Cdd:PLN03192  659 LQVAMAEDHVDMVRLLIMNGADVDKANTDDDF 690

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

144-226

3.02e-09

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 61.07 E-value: 3.02e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   144 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 223
Cdd:PTZ00322   86 LCQLAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165


                  ...
gi 63100468   224 YLL 226
Cdd:PTZ00322  166 LLS 168

Ank_4

Ankyrin repeats (many copies);

74-127

4.73e-09

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 53.05 E-value: 4.73e-09

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468     74 WLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLV 127
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

208-345

5.21e-09

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 60.03 E-value: 5.21e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  208 TPLHAAASSGMISVVKYLLDL-GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAN-VNQKNE----KGFTPLHFAAA 281
Cdd:cd22192   19 SPLLLAAKENDVQAIKKLLKCpSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPElVNEPMTsdlyQGETALHIAVV 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63100468  282 STHGALcLELLVGNGADVN---------MKSKD-----GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHI 345
Cdd:cd22192   99 NQNLNL-VRELIARGADVVspratgtffRPGPKnliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175

Ank_4

Ankyrin repeats (many copies);

109-160

6.66e-09

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 52.66 E-value: 6.66e-09

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 63100468    109 TPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL 160
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PHA03100

ankyrin repeat protein; Provisional

22-106

9.24e-09

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 58.91 E-value: 9.24e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    22 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVN 101
Cdd:PHA03100  173 NRVNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIK 252


                  ....*
gi 63100468   102 ARDKN 106
Cdd:PHA03100  253 TIIET 257

PHA02874

ankyrin repeat protein; Provisional

816-976

1.03e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 58.82 E-value: 1.03e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   816 VNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSAsADLTLQDKSKNTALH 895
Cdd:PHA02874  117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKG-AYANVKDNNGESPLH 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   896 LACGKGHETSALLILEKITdrNLINATNAALqTPLHVAARNGLTMVvqELLGKGASVLAVDENGYTP---ALACAPNKDV 972
Cdd:PHA02874  196 NAAEYGDYACIKLLIDHGN--HIMNKCKNGF-TPLHNAIIHNRSAI--ELLINNASINDQDIDGSTPlhhAINPPCDIDI 270


                  ....
gi 63100468   973 ADCL 976
Cdd:PHA02874  271 IDIL 274

PHA02878

ankyrin repeat protein; Provisional

457-662

1.11e-08

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 58.74 E-value: 1.11e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   457 LVGSGASVNDLDE-RGCTPLHYAATsDTDGKCLEYLLRNDANPGIRDKqgynavhysaayghrlclqliasetpldvlme 535
Cdd:PHA02878  153 LLSYGADINMKDRhKGNTALHYATE-NKDQRLTELLLSYGANVNIPDK-------------------------------- 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   536 tsgtdmlsdSDNratiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAfkGHVECVDV---LINQGASILVK 612
Cdd:PHA02878  200 ---------TNN----SPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISV--GYCKDYDIlklLLEHGVDVNAK 264

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 63100468   613 DYVLKRTPIHAAAtngHSE-CLRLLIGNAEPQNAVDIQDgngQTPLMLSVL 662
Cdd:PHA02878  265 SYILGLTALHSSI---KSErKLKLLLEYGADINSLNSYK---LTPLSSAVK 309

PHA02875

ankyrin repeat protein; Provisional

719-880

2.17e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 57.69 E-value: 2.17e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   719 GRTPIHLSAACGHIGVLGALLQSATSVDANPAVVDnhgyTALHWACYNGHETCVELLLE-----QDVFQKiDGNafSPLH 793
Cdd:PHA02875   35 GISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIE----SELHDAVEEGDVKAVEELLDlgkfaDDVFYK-DGM--TPLH 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   794 CAVINDNEGAAEMLIDSLGASIVNATDSKgrTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVE 873
Cdd:PHA02875  108 LATILKKLDIMKLLIARGADPDIPNTDKF--SPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICK 185


                  ....*..
gi 63100468   874 MLVSSAS 880
Cdd:PHA02875  186 MLLDSGA 192

PLN03192

Voltage-dependent potassium channel; Provisional

445-693

2.20e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 58.34 E-value: 2.20e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   445 AAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDgKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHrlclqli 524
Cdd:PLN03192  532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYE-DCVLVLLKHACNVHIRDANGNTALWNAISAKH------- 603

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   525 asETPLDVLMETSgtdmlSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLIN 604
Cdd:PLN03192  604 --HKIFRILYHFA-----SISDPHAAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIM 676

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   605 QGASIlvkdyvlkrtpIHAAATNGHS-ECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCvySLLNKGANvdaKD 683
Cdd:PLN03192  677 NGADV-----------DKANTDDDFSpTELRELLQKRELGHSITIVDSVPADEPDLGRDGGSRPG--RLQGTSSD---NQ 740

                         250
                  ....*....|
gi 63100468   684 KWGRTALHRG 693
Cdd:PLN03192  741 CRPRVSIYKG 750

Ank_4

Ankyrin repeats (many copies);

583-637

2.31e-08

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.12 E-value: 2.31e-08

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 63100468    583 GRTPLDLAAFKGHVECVDVLINQGASILVKDYvLKRTPIHAAATNGHSECLRLLI 637
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDG-NGETALHFAASNGNVEVLKLLL 54

PHA02874

ankyrin repeat protein; Provisional

792-962

2.48e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 57.67 E-value: 2.48e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   792 LHCAVINDNEGAAEMLIDsLGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNT 871
Cdd:PHA02874  128 LHYAIKKGDLESIKMLFE-YGAD-VNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYAC 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   872 VEMLVSSASadlTLQDKSKN--TALHLACgkGHETSALLILekITDRNlINATNAALQTPLHVAARNGLTM-VVQELLGK 948
Cdd:PHA02874  206 IKLLIDHGN---HIMNKCKNgfTPLHNAI--IHNRSAIELL--INNAS-INDQDIDGSTPLHHAINPPCDIdIIDILLYH 277

                         170
                  ....*....|....
gi 63100468   949 GASVLAVDENGYTP 962
Cdd:PHA02874  278 KADISIKDNKGENP 291

Ank_4

Ankyrin repeats (many copies);

42-94

3.22e-08

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 50.74 E-value: 3.22e-08

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 63100468     42 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILL 94
Cdd:pfam13637    2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PHA02875

ankyrin repeat protein; Provisional

730-981

3.42e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 56.92 E-value: 3.42e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   730 GHIGVLGALLQSATsvdaNPAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDG-NAFSPLHCAVINDNEGAAEMLI 808
Cdd:PHA02875   13 GELDIARRLLDIGI----NPNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYpDIESELHDAVEEGDVKAVEELL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   809 DSlGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSaSADLTLQDk 888
Cdd:PHA02875   89 DL-GKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDH-KACLDIED- 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   889 skntalhlACGkghetsallilekitdrnlinatnaalQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAP 968
Cdd:PHA02875  166 --------CCG---------------------------CTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAI 210

                         250
                  ....*....|...
gi 63100468   969 NKDVADCLALILA 981
Cdd:PHA02875  211 ENNKIDIVRLFIK 223

PHA02859

ankyrin repeat protein; Provisional

206-364

3.90e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 54.83 E-value: 3.90e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   206 SYT-PLHAAASSGMISVVKYLLDLgvdMNEPNAYGNTPLHvACYNGQDVVVNE---LIDCGANVNQK-NEKGFTPLHFAA 280
Cdd:PHA02859   20 RYCnPLFYYVEKDDIEGVKKWIKF---VNDCNDLYETPIF-SCLEKDKVNVEIlkfLIENGADVNFKtRDNNLSALHHYL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   281 ASTHGAL--CLELLVGNGADVNMKSKDGKTPLH--MTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLI- 355
Cdd:PHA02859   96 SFNKNVEpeILKILIDSGSSITEEDEDGKNLLHmyMCNFNVRINVIKLLIDSGVSFLNKDFDNNNILYSYILFHSDKKIf 175


                  ....*....
gi 63100468   356 NTLITSGAD 364
Cdd:PHA02859  176 DFLTSLGID 184

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

189-261

4.39e-08

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 57.22 E-value: 4.39e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468   189 VKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC 261
Cdd:PTZ00322   98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

83-161

4.83e-08

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 57.22 E-value: 4.83e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468    83 ASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLS 161
Cdd:PTZ00322   91 ASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSR 169

Ank_4

Ankyrin repeats (many copies);

686-739

5.58e-08

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.97 E-value: 5.58e-08

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    686 GRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 739
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PHA02798

ankyrin-like protein; Provisional

254-478

5.99e-08

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 56.38 E-value: 5.99e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   254 VVNELIDCGANVNQKNEKGFTPLHFAAAS----THGALCLELLVGNGADVNMKSKDGKTPLHmTALHGRFSRSQTI---- 325
Cdd:PHA02798   53 IVKLFINLGANVNGLDNEYSTPLCTILSNikdyKHMLDIVKILIENGADINKKNSDGETPLY-CLLSNGYINNLEIllfm 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   326 IQSGAVIDCEDKNGNTPLHIAARYGHEL---LINTLITSGADTAKRG-------IHGMFPLHLAALSgfSDCCRKLLSSG 395
Cdd:PHA02798  132 IENGADTTLLDKDGFTMLQVYLQSNHHIdieIIKLLLEKGVDINTHNnkekydtLHCYFKYNIDRID--ADILKLFVDNG 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   396 FDIDTPDDFGRTCLHAAAAGGNLECLNLLLN------TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDE 469
Cdd:PHA02798  210 FIINKENKSHKKKFMEYLNSLLYDNKRFKKNildfifSYIDINQVDELGFNPLYYSVSHNNRKIFEYLLQLGGDINIITE 289


                  ....*....
gi 63100468   470 RGCTPLHYA 478
Cdd:PHA02798  290 LGNTCLFTA 298

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

574-797

6.33e-08

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 56.63 E-value: 6.33e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    574 LDLDVRNSSGRTPLDLAAFKG-HVECVDVLINQGASILVKDyvlkrTPIHAAATNGH---SECLRLLIGNAE----PQNA 645
Cdd:TIGR00870   43 LNINCPDRLGRSALFVAAIENeNLELTELLLNLSCRGAVGD-----TLLHAISLEYVdavEAILLHLLAAFRksgpLELA 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    646 VDIQDGN---GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK--------------WGRTALHRGAVTGHEECVDALLQH 708
Cdd:TIGR00870  118 NDQYTSEftpGITALHLAAHRQNYEIVKLLLERGASVPARACgdffvksqgvdsfyHGESPLNAAACLGSPSIVALLSED 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    709 GAKCLLRDSRGRTPIHLSA------------ACG-HIGVLGALLQSATSVDANpAVVDNHGYTALHWACYNGHETCVELL 775
Cdd:TIGR00870  198 PADILTADSLGNTLLHLLVmenefkaeyeelSCQmYNFALSLLDKLRDSKELE-VILNHQGLTPLKLAAKEGRIVLFRLK 276

                          250       260
                   ....*....|....*....|...
gi 63100468    776 LEQDVFQ-KIDGNAFSPLHCAVI 797
Cdd:TIGR00870  277 LAIKYKQkKFVAWPNGQQLLSLY 299

PLN03192

Voltage-dependent potassium channel; Provisional

279-433

6.49e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 56.80 E-value: 6.49e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   279 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 358
Cdd:PLN03192  531 TVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRIL 610

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468   359 --ITSGADTAKRGIhgmfPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNK 433
Cdd:PLN03192  611 yhFASISDPHAAGD----LLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDK 683

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

820-948

6.90e-08

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a temperature-sensitive Transient Receptor Potential (TRP) ion channel that is activated by warm temperatures, synthetic small-molecule chemicals, and natural compounds from plants. TRPV3 function is regulated by physiological factors such as extracellular divalent cations and acidic pH, intracellular adenosine triphosphate, membrane voltage, and arachidonic acid. It is expressed in both neuronal and non-neuronal tissues including epidermal keratinocytes, epithelial cells in the gut, endothelial cells in blood vessels, and neurons in dorsal root ganglia and CNS. TRPV3 null mice have abnormal hair morphogenesis and compromised skin barrier function. It may play roles in inflammatory skin disorders, such as itch and pain sensation. TRPV3 is also expressed by many neuronal and non-neuronal tissues, showing that TRPV3 might play roles in other unknown cellular and physiological functions. TRPV3 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 56.69 E-value: 6.90e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  820 DSKGRTPLHAAAFTDHVECLQLLLSQNAQVNS-ADST-------------GKTPLMMAAENGQTNTVEMLVSSASADLTL 885
Cdd:cd22194  138 AYEGQTALNIAIERRQGDIVKLLIAKGADVNAhAKGVffnpkykhegfyfGETPLALAACTNQPEIVQLLMEKESTDITS 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 63100468  886 QDKSKNTALHLAC-----GKGHETSAL----LILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGK 948
Cdd:cd22194  218 QDSRGNTVLHALVtvaedSKTQNDFVKrmydMILLKSENKNLETIRNNEGLTPLQLAAKMGKAEILKYILSR 289

PHA02875

ankyrin repeat protein; Provisional

652-875

8.11e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 55.77 E-value: 8.11e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   652 NGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAkcLLRD---SRGRTPIHLSAA 728
Cdd:PHA02875   34 DGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGK--FADDvfyKDGMTPLHLATI 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   729 CGHIGVLGALLQSAtsvdANPAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKI-DGNAFSPLHCAVINDNEGAAEML 807
Cdd:PHA02875  112 LKKLDIMKLLIARG----ADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIeDCCGCTPLIIAMAKGDIAICKML 187

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 63100468   808 IDSlGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNsadstgktpLMMAAENGQTNTVEML 875
Cdd:PHA02875  188 LDS-GANIDYFGKNGCVAALCYAIENNKIDIVRLFIKRGADCN---------IMFMIEGEECTILDMI 245

PHA02716

CPXV016; CPX019; EVM010; Provisional

33-261

1.18e-07

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 56.07 E-value: 1.18e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    33 DVNFQDNEKRTP-LHAaaYLG----DAEIIELLILSGARVNAKDSKWLTPLHRAV--ASCSEEAVQILLKHSADVNARDK 105
Cdd:PHA02716  168 NLNYVCKKTGYGiLHA--YLGnmyvDIDILEWLCNNGVNVNLQNNHLITPLHTYLitGNVCASVIKKIIELGGDMDMKCV 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   106 NWQTPLHIAAANkavkcAESLVPLLSNVNVSDRAGRTA------LH---HAAFSGHGEMVKLLLSRGANINAFDKKDRRA 176
Cdd:PHA02716  246 NGMSPIMTYIIN-----IDNINPEITNIYIESLDGNKVknipmiLHsyiTLARNIDISVVYSFLQPGVKLHYKDSAGRTC 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   177 IHwaAYMG----HIEVVKLLVSHGAEVTCKDKKSYTPLHAAAS--------------SGMISVVKYLLDLGVDMNEPNAY 238
Cdd:PHA02716  321 LH--QYILrhniSTDIIKLLHEYGNDLNEPDNIGNTVLHTYLSmlsvvnildpetdnDIRLDVIQCLISLGADITAVNCL 398

                         250       260
                  ....*....|....*....|...
gi 63100468   239 GNTPLHVACYNGQDVVVNELIDC 261
Cdd:PHA02716  399 GYTPLTSYICTAQNYMYYDIIDC 421

Ank_4

Ankyrin repeats (many copies);

823-876

1.36e-07

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.20 E-value: 1.36e-07

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    823 GRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLV 876
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

28-247

1.63e-07

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 55.47 E-value: 1.63e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468     28 IFKKEDVNFQDNEKrtplhaaAYLGDAEIIELLILSGARVNAK-------DSKWLTPLHRAVA-SCSEEAVQILLKHSAD 99
Cdd:TIGR00870    6 IVPAEESPLSDEEK-------AFLPAAERGDLASVYRDLEEPKklnincpDRLGRSALFVAAIeNENLELTELLLNLSCR 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    100 VNARDknwqTPLHIAAANKAVKCAESLVPLLSN---------VNVSDR----AGRTALHHAAFSGHGEMVKLLLSRGANI 166
Cdd:TIGR00870   79 GAVGD----TLLHAISLEYVDAVEAILLHLLAAfrksgplelANDQYTseftPGITALHLAAHRQNYEIVKLLLERGASV 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    167 NA------FDKKDRRA--------IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA------------SSGMIS 220
Cdd:TIGR00870  155 PAracgdfFVKSQGVDsfyhgespLNAAACLGSPSIVALLSEDPADILTADSLGNTLLHLLVmenefkaeyeelSCQMYN 234

                          250       260       270
                   ....*....|....*....|....*....|.
gi 63100468    221 VVKYLLDLGVDMNE----PNAYGNTPLHVAC 247
Cdd:TIGR00870  235 FALSLLDKLRDSKEleviLNHQGLTPLKLAA 265

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

809-890

1.74e-07

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 55.29 E-value: 1.74e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   809 DSLGASIV-------NATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSASA 881
Cdd:PTZ00322   94 DAVGARILltggadpNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQC 173


                  ....*....
gi 63100468   882 DLTLQDKSK 890
Cdd:PTZ00322  174 HFELGANAK 182

Ank_4

Ankyrin repeats (many copies);

438-492

2.50e-07

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 48.42 E-value: 2.50e-07

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 63100468    438 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLL 492
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNG-NVEVLKLLL 54

PHA02875

ankyrin repeat protein; Provisional

22-167

5.14e-07

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 53.46 E-value: 5.14e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    22 DEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVN 101
Cdd:PHA02875  116 DIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANID 195

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468   102 ArdknwqtplhiaaankavkcaeslvpllsnvnVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 167
Cdd:PHA02875  196 Y--------------------------------FGKNGCVAALCYAIENNKIDIVRLFIKRGADCN 229

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

843-952

7.00e-07

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 53.48 E-value: 7.00e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  843 LSQNAQVNSadstgkTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEkiTDRNLIN-A 921
Cdd:cd22192   10 LLQQKRISE------SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLME--AAPELVNeP 81

                         90       100       110
                 ....*....|....*....|....*....|....
gi 63100468  922 TNAAL---QTPLHVAARNGLTMVVQELLGKGASV 952
Cdd:cd22192   82 MTSDLyqgETALHIAVVNQNLNLVRELIARGADV 115

Ank_4

Ankyrin repeats (many copies);

790-843

7.94e-07

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.88 E-value: 7.94e-07

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    790 SPLHCAVINDNEGAAEMLIDSlGASIvNATDSKGRTPLHAAAFTDHVECLQLLL 843
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEK-GADI-NAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

705-878

9.77e-07

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 52.71 E-value: 9.77e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  705 LLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDANPAVVDNH-GYTALHWACYNGHETCVELLLEQ--DV- 780
Cdd:cd22192   37 LKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMTSDLYqGETALHIAVVNQNLNLVRELIARgaDVv 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  781 --------FQKIDGNAF----SPLHCAVINDNEGAAEMLIDSlGASIVnATDSKGRTPLHAAAF----TDHVECLQLLLS 844
Cdd:cd22192  117 spratgtfFRPGPKNLIyygeHPLSFAACVGNEEIVRLLIEH-GADIR-AQDSLGNTVLHILVLqpnkTFACQMYDLILS 194

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 63100468  845 QNAQVNSA------DSTGKTPLMMAAENGQTNTVEMLVSS 878
Cdd:cd22192  195 YDKEDDLQpldlvpNNQGLTPFKLAAKEGNIVMFQHLVQK 234

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

281-350

1.16e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 52.59 E-value: 1.16e-06

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   281 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYG 350
Cdd:PTZ00322   90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

190-374

1.17e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 52.71 E-value: 1.17e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  190 KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDM-NEP---NAY-GNTPLHVACYNGQDVVVNELIDCGAN 264
Cdd:cd22192   35 KLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELvNEPmtsDLYqGETALHIAVVNQNLNLVRELIARGAD 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  265 VN---------QKNEK-----GFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALhgrfsrsqtiiQSGA 330
Cdd:cd22192  115 VVspratgtffRPGPKnliyyGEHPLSFAACVGNEEI-VRLLIEHGADIRAQDSLGNTVLHILVL-----------QPNK 182

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 63100468  331 VIDCE--------DKNGN-------------TPLHIAARYGHELLINTLITSgadtaKRGIHGMF 374
Cdd:cd22192  183 TFACQmydlilsyDKEDDlqpldlvpnnqglTPFKLAAKEGNIVMFQHLVQK-----RRHIQWTY 242

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

274-479

1.45e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 52.32 E-value: 1.45e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  274 TPLhFAAASTHGALCLE-LLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA-----VIDCEDKNGNTPLHIAA 347
Cdd:cd22192   19 SPL-LLAAKENDVQAIKkLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPelvnePMTSDLYQGETALHIAV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  348 RYGHELLINTLITSGADTAKRGIHGMFplhlaalsgFSDCCRKLLSsgfdidtpddFGRTCLHAAAAGGNLECLNLLLNT 427
Cdd:cd22192   98 VNQNLNLVRELIARGADVVSPRATGTF---------FRPGPKNLIY----------YGEHPLSFAACVGNEEIVRLLIEH 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468  428 GADFNKKDKFGRSPLHYAA--ANCNYQC-----LFALVGSGASVNdLD----ERGCTPLHYAA 479
Cdd:cd22192  159 GADIRAQDSLGNTVLHILVlqPNKTFACqmydlILSYDKEDDLQP-LDlvpnNQGLTPFKLAA 220

Ank_4

Ankyrin repeats (many copies);

655-706

1.63e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.11 E-value: 1.63e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 63100468    655 TPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 706
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

767-951

1.68e-06

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 52.19 E-value: 1.68e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  767 GHETCVELLLEQDVFQKiDGNAFSPLHCAVINDNEG---AAEMLIDSLGAS-----IVNA--TDS--KGRTPLHAAAFTD 834
Cdd:cd21882    6 GLLECLRWYLTDSAYQR-GATGKTCLHKAALNLNDGvneAIMLLLEAAPDSgnpkeLVNApcTDEfyQGQTALHIAIENR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  835 HVECLQLLLSQNAQVNSADST-------------GKTPLMMAAENGQTNTVEMLVSSAS--ADLTLQDKSKNTALH---L 896
Cdd:cd21882   85 NLNLVRLLVENGADVSARATGrffrkspgnlfyfGELPLSLAACTNQEEIVRLLLENGAqpAALEAQDSLGNTVLHalvL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 63100468  897 ACGKGHETSA--------LLILEKITD--RNLINATNAALQTPLHVAARNGLTMVVQELLGKGAS 951
Cdd:cd21882  165 QADNTPENSAfvcqmynlLLSYGAHLDptQQLEEIPNHQGLTPLKLAAVEGKIVMFQHILQREFS 229

Ank_4

Ankyrin repeats (many copies);

618-673

1.87e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.73 E-value: 1.87e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    618 RTPIHAAATNGHSECLRLLIGNAEPqnaVDIQDGNGQTPLMLSVLNGHTDCVYSLL 673
Cdd:pfam13637    2 LTALHAAAASGHLELLRLLLEKGAD---INAVDGNGETALHFAASNGNVEVLKLLL 54

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

694-776

2.16e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 51.82 E-value: 2.16e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   694 AVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQsatsVDANPAVVDNHGYTALHWACYNGHETCVE 773
Cdd:PTZ00322   90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLE----FGADPTLLDKDGKTPLELAEENGFREVVQ 165


                  ...
gi 63100468   774 LLL 776
Cdd:PTZ00322  166 LLS 168

Ank_5

Ankyrin repeats (many copies);

258-312

2.19e-06

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.80 E-value: 2.19e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468    258 LIDCG-ANVNQKNEKGFTPLHFAAasTHGAL-CLELLVGNGADVNMKSKDGKTPLHM 312
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAA--KYGALeIVRVLLAYGVDLNLKDEEGLTALDL 55

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

12-97

2.31e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 51.82 E-value: 2.31e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQ 91
Cdd:PTZ00322   86 LCQLAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165


                  ....*.
gi 63100468    92 ILLKHS 97
Cdd:PTZ00322  166 LLSRHS 171

Ank_5

Ankyrin repeats (many copies);

192-246

3.05e-06

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.42 E-value: 3.05e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    192 LVSHG-AEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 246
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

140-171

5.07e-06

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 44.20 E-value: 5.07e-06

                           10        20        30
                   ....*....|....*....|....*....|...
gi 63100468    140 GRTALHHAAFS-GHGEMVKLLLSRGANINAFDK 171
Cdd:pfam00023    2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34

Ank_4

Ankyrin repeats (many copies);

375-416

5.18e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.57 E-value: 5.18e-06

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 63100468    375 PLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGG 416
Cdd:pfam13637    4 ALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNG 45

Ank_4

Ankyrin repeats (many copies);

756-808

5.33e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.57 E-value: 5.33e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    756 GYTALHWACYNGHETCVELLLEQDV-FQKIDGNAFSPLHCAVINDNEGAAEMLI 808
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGAdINAVDGNGETALHFAASNGNVEVLKLLL 54

PLN03192

Voltage-dependent potassium channel; Provisional

768-962

5.42e-06

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 50.64 E-value: 5.42e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   768 HETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDS-LGASIvnaTDSKGRTPLHAAAFTDHVECLQLLLSQN 846
Cdd:PLN03192  505 HDLNVGDLLGDNGGEHDDPNMASNLLTVASTGNAALLEELLKAkLDPDI---GDSKGRTPLHIAASKGYEDCVLVLLKHA 581

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   847 AQVNSADSTGKTPLMMAAENGQTNTVEMLVSSASADltlQDKSKNTALHLACGKGHETSALLILEKITDrnlINATNAAL 926
Cdd:PLN03192  582 CNVHIRDANGNTALWNAISAKHHKIFRILYHFASIS---DPHAAGDLLCTAAKRNDLTAMKELLKQGLN---VDSEDHQG 655

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 63100468   927 QTPLHVAARNGLTMVVQELLGKGASVLAVD-ENGYTP 962
Cdd:PLN03192  656 ATALQVAMAEDHVDMVRLLIMNGADVDKANtDDDFSP 692

PHA02875

ankyrin repeat protein; Provisional

439-657

6.32e-06

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 49.99 E-value: 6.32e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   439 RSPLHYAAANCNYQCLFALVGSGASVND-LDERGCTPLHYAaTSDTDGKCLEYLLRNDANPGIrdkqgynavhysaaygh 517
Cdd:PHA02875   69 ESELHDAVEEGDVKAVEELLDLGKFADDvFYKDGMTPLHLA-TILKKLDIMKLLIARGADPDI----------------- 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   518 rlclqliasetpldvlmetSGTDmlsdsdnraTISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 597
Cdd:PHA02875  131 -------------------PNTD---------KFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIA 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468   598 CVDVLINQGASIlvkDYVLKRTPIHA---AATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPL 657
Cdd:PHA02875  183 ICKMLLDSGANI---DYFGKNGCVAAlcyAIENNKIDIVRLFIKRGADCNIMFMIEGEECTIL 242

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

214-320

6.85e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 50.28 E-value: 6.85e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   214 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALcLELLV 293
Cdd:PTZ00322   90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREV-VQLLS 168

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 63100468   294 GN-------GADVNMKSKDGKTPLH----MTALHGRFS 320
Cdd:PTZ00322  169 RHsqchfelGANAKPDSFTGKPPSLedspISSHHPDFS 206

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

43-180

7.55e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 50.01 E-value: 7.55e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   43 TPLHAAAYLGDAEIIELLILSGARVNA---------KDSKWLT-----PLHRAVASCSEEAVQILLKHSADVNARDKNWQ 108
Cdd:cd22192   91 TALHIAVVNQNLNLVRELIARGADVVSpratgtffrPGPKNLIyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLGN 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  109 TPLHIAA--ANKAVKCAE-----SLVPLLSNVNVS---DRAGRTALHHAAFSGHGEMVKLLLSRganinafdkkdRRAIH 178
Cdd:cd22192  171 TVLHILVlqPNKTFACQMydlilSYDKEDDLQPLDlvpNNQGLTPFKLAAKEGNIVMFQHLVQK-----------RRHIQ 239


                 ..
gi 63100468  179 WA 180
Cdd:cd22192  240 WT 241

Ank_4

Ankyrin repeats (many copies);

308-359

8.05e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.19 E-value: 8.05e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 63100468    308 TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLI 359
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_4

Ankyrin repeats (many copies);

239-293

8.05e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.19 E-value: 8.05e-06

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 63100468    239 GNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGAlCLELLV 293
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVE-VLKLLL 54

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

108-259

1.39e-05

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 49.11 E-value: 1.39e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  108 QTPLHIAAANKAVKCAESLVPLLSNVNVSDRA--------------GRTALHHAAFSGHGEMVKLLLSRGANINA----- 168
Cdd:cd21882   27 KTCLHKAALNLNDGVNEAIMLLLEAAPDSGNPkelvnapctdefyqGQTALHIAIENRNLNLVRLLVENGADVSAratgr 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  169 -FDKKDRRAIHW-------AAYMGHIEVVKLLVSHGAE---VTCKDKKSYTPLHA---------AASSGMISVVKYLLDL 228
Cdd:cd21882  107 fFRKSPGNLFYFgelplslAACTNQEEIVRLLLENGAQpaaLEAQDSLGNTVLHAlvlqadntpENSAFVCQMYNLLLSY 186

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 63100468  229 G------VDMNE-PNAYGNTPLHVACYNGQDVVVNELI 259
Cdd:cd21882  187 GahldptQQLEEiPNHQGLTPLKLAAVEGKIVMFQHIL 224

Ank_5

Ankyrin repeats (many copies);

93-147

1.45e-05

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 43.49 E-value: 1.45e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468     93 LLKH-SADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHA 147
Cdd:pfam13857    1 LLEHgPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

140-168

1.74e-05

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 42.57 E-value: 1.74e-05

                            10        20
                    ....*....|....*....|....*....
gi 63100468     140 GRTALHHAAFSGHGEMVKLLLSRGANINA 168
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

325-404

1.87e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 48.74 E-value: 1.87e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   325 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS---SGFDIDT- 400
Cdd:PTZ00322  101 LLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRhsqCHFELGAn 180


                  ....*.
gi 63100468   401 --PDDF 404
Cdd:PTZ00322  181 akPDSF 186

Ank_4

Ankyrin repeats (many copies);

12-61

1.89e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 1.89e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468     12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLI 61
Cdd:pfam13637    5 LHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_4

Ankyrin repeats (many copies);

405-458

2.13e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 2.13e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    405 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 458
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

473-675

2.22e-05

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 48.47 E-value: 2.22e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  473 TPLHYAAtSDTDGKCLEYLLR-NDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSgtdmlsdSDNRATI 551
Cdd:cd22192   19 SPLLLAA-KENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMT-------SDLYQGE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  552 SPLHLAAYHGHhqalEVLVQSLLD--LDVRNSS----------------GRTPLDLAAFKGHVECVDVLINQGASILVKD 613
Cdd:cd22192   91 TALHIAVVNQN----LNLVRELIArgADVVSPRatgtffrpgpknliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468  614 YvLKRTPIHAAAT--NGHSECLRL-LIGNAEP---QNAVD-IQDGNGQTPLMLSVLNGHTDCVYSLLNK 675
Cdd:cd22192  167 S-LGNTVLHILVLqpNKTFACQMYdLILSYDKeddLQPLDlVPNNQGLTPFKLAAKEGNIVMFQHLVQK 234

PHA02716

CPXV016; CPX019; EVM010; Provisional

254-475

2.26e-05

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 48.37 E-value: 2.26e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   254 VVNELIDCG-ANVNQK-NEKGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRS--QTIIQS 328
Cdd:PHA02716  157 LIKYMVDVGiVNLNYVcKKTGYGILHAYLGNMYVDIdILEWLCNNGVNVNLQNNHLITPLHTYLITGNVCASviKKIIEL 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   329 GAVIDCEDKNGNTPLH---IAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFS-DCCRKLLSSGFDIDTPDDF 404
Cdd:PHA02716  237 GGDMDMKCVNGMSPIMtyiINIDNINPEITNIYIESLDGNKVKNIPMILHSYITLARNIDiSVVYSFLQPGVKLHYKDSA 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   405 GRTCLHAAAAGGNLECL--NLLLNTGADFNKKDKFGRSPLHYAAA--------------NCNYQCLFALVGSGASVNDLD 468
Cdd:PHA02716  317 GRTCLHQYILRHNISTDiiKLLHEYGNDLNEPDNIGNTVLHTYLSmlsvvnildpetdnDIRLDVIQCLISLGADITAVN 396


                  ....*..
gi 63100468   469 ERGCTPL 475
Cdd:PHA02716  397 CLGYTPL 403

Ank_5

Ankyrin repeats (many copies);

643-691

2.47e-05

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 42.72 E-value: 2.47e-05

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 63100468    643 QNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALH 691
Cdd:pfam13857    6 PIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALD 54

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

695-869

2.74e-05

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 47.95 E-value: 2.74e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  695 VTGHEECVDALLQHGAKclLRDSRGRTPIHLSAACGHIGVLGA---LLQSATSVDANPAVVDN-------HGYTALHWAC 764
Cdd:cd21882    4 LLGLLECLRWYLTDSAY--QRGATGKTCLHKAALNLNDGVNEAimlLLEAAPDSGNPKELVNApctdefyQGQTALHIAI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  765 YNGHETCVELLLEQ----------DVFQKIDGNAF----SPLHCAVINDNEGAAEMLIDSlGASI--VNATDSKGRTPLH 828
Cdd:cd21882   82 ENRNLNLVRLLVENgadvsaratgRFFRKSPGNLFyfgeLPLSLAACTNQEEIVRLLLEN-GAQPaaLEAQDSLGNTVLH 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468  829 A-----------AAFTDHVecLQLLLSQNAQVNS-------ADSTGKTPLMMAAENGQT 869
Cdd:cd21882  161 AlvlqadntpenSAFVCQM--YNLLLSYGAHLDPtqqleeiPNHQGLTPLKLAAVEGKI 217

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

52-117

3.02e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.97 E-value: 3.02e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    52 GDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAAN 117
Cdd:PTZ00322   93 GDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEEN 158

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

724-864

3.21e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.97 E-value: 3.21e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   724 HLSAACGHIGVLgALLQSAtsvdANPAVVDNHGYTALHWACYNGHETCVELLLEqdvfqkidgnafsplhcavindnega 803
Cdd:PTZ00322   88 QLAASGDAVGAR-ILLTGG----ADPNCRDYDGRTPLHIACANGHVQVVRVLLE-------------------------- 136

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63100468   804 aemlidsLGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGK-------------TPLMMAA 864
Cdd:PTZ00322  137 -------FGAD-PTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFELGANAKpdsftgkppsledSPISSHH 202

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

112-198

3.26e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.97 E-value: 3.26e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   112 HIAAANKAVKcAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKL 191
Cdd:PTZ00322   88 QLAASGDAVG-ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQL 166


                  ....*..
gi 63100468   192 LVSHGAE 198
Cdd:PTZ00322  167 LSRHSQC 173

Ank_4

Ankyrin repeats (many copies);

339-392

3.48e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 42.26 E-value: 3.48e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    339 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLL 392
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_5

Ankyrin repeats (many copies);

225-279

3.52e-05

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 42.33 E-value: 3.52e-05

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    225 LLDLG-VDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFA 279
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

140-168

3.90e-05

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 41.47 E-value: 3.90e-05

                           10        20
                   ....*....|....*....|....*....
gi 63100468    140 GRTALHHAAFSGHGEMVKLLLSRGANINA 168
Cdd:pfam13606    2 GNTPLHLAARNGRLEIVKLLLENGADINA 30

PHA02874

ankyrin repeat protein; Provisional

803-980

4.24e-05

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 47.27 E-value: 4.24e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   803 AAEMLIDSLGaSIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSS---- 878
Cdd:PHA02874   16 AIEKIIKNKG-NCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNgvdt 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   879 ------------------ASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNlINATNAALqtPLHVAARNGLTM 940
Cdd:PHA02874   95 silpipciekdmiktildCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVN-IEDDNGCY--PIHIAIKHNFFD 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 63100468   941 VVQELLGKGASVLAVDENGYTPALACAPNKDVAdCLALIL 980
Cdd:PHA02874  172 IIKLLLEKGAYANVKDNNGESPLHNAAEYGDYA-CIKLLI 210

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

550-660

4.67e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.59 E-value: 4.67e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   550 TISPLHLAAyHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGA--SILVKDyvlKRTPIHAAATN 627
Cdd:PTZ00322   83 TVELCQLAA-SGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGAdpTLLDKD---GKTPLELAEEN 158

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 63100468   628 GHSECLRLLIG----------NAEPQNAVDIQDGNGQTPLMLS 660
Cdd:PTZ00322  159 GFREVVQLLSRhsqchfelgaNAKPDSFTGKPPSLEDSPISSH 201

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

830-959

4.75e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.59 E-value: 4.75e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   830 AAFTDHVECLQLllSQNAQVNSA------DSTGKTPLMMA-------AENGQTNTVEMLVSSAsADLTLQDKSKNTALHL 896
Cdd:PTZ00322   45 ARIDTHLEALEA--TENKDATPDhnltteEVIDPVVAHMLtvelcqlAASGDAVGARILLTGG-ADPNCRDYDGRTPLHI 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468   897 ACGKGHETSALLILEKITDRNLINATNaalQTPLHVAARNGLTMVVQELLGKGASVLAVDENG 959
Cdd:PTZ00322  122 ACANGHVQVVRVLLEFGADPTLLDKDG---KTPLELAEENGFREVVQLLSRHSQCHFELGANA 181

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

238-266

5.88e-05

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 41.03 E-value: 5.88e-05

                            10        20
                    ....*....|....*....|....*....
gi 63100468     238 YGNTPLHVACYNGQDVVVNELIDCGANVN 266
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29

Ank_4

Ankyrin repeats (many copies);

274-320

6.03e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.49 E-value: 6.03e-05

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 63100468    274 TPLHFAAASTHGAlCLELLVGNGADVNMKSKDGKTPLHMTALHGRFS 320
Cdd:pfam13637    3 TALHAAAASGHLE-LLRLLLEKGADINAVDGNGETALHFAASNGNVE 48

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

234-350

6.21e-05

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 47.06 E-value: 6.21e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  234 EPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQK----------NEKGF----TPLHFAAASTHGALcLELLVGNGAD- 298
Cdd:cd22194  136 EEAYEGQTALNIAIERRQGDIVKLLIAKGADVNAHakgvffnpkyKHEGFyfgeTPLALAACTNQPEI-VQLLMEKESTd 214

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63100468  299 VNMKSKDGKTPLHMTALHGRFSRSQT--IIQSGAVI--DCEDKN--------GNTPLHIAARYG 350
Cdd:cd22194  215 ITSQDSRGNTVLHALVTVAEDSKTQNdfVKRMYDMIllKSENKNletirnneGLTPLQLAAKMG 278

PHA02946

ankyin-like protein; Provisional

390-510

6.47e-05

ankyin-like protein; Provisional

Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 46.59 E-value: 6.47e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   390 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN--YQCLFALVGSGASVND- 466
Cdd:PHA02946   57 ELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDevIERINLLVQYGAKINNs 136

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 63100468   467 LDERGCTPLhyAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVH 510
Cdd:PHA02946  137 VDEEGCGPL--LACTDPSERVFKKIMSIGFEARIVDKFGKNHIH 178

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

238-270

7.18e-05

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 40.74 E-value: 7.18e-05

                           10        20        30
                   ....*....|....*....|....*....|....
gi 63100468    238 YGNTPLHVACY-NGQDVVVNELIDCGANVNQKNE 270
Cdd:pfam00023    1 DGNTPLHLAAGrRGNLEIVKLLLSKGADVNARDK 34

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

378-597

9.07e-05

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 46.41 E-value: 9.07e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  378 LAALSGFSDCCRKLLSSgfDIDTPDDFGRTCLHAAA---AGGNLECLNLLLNTGADFNKKDKF-----------GRSPLH 443
Cdd:cd21882    1 LEELLGLLECLRWYLTD--SAYQRGATGKTCLHKAAlnlNDGVNEAIMLLLEAAPDSGNPKELvnapctdefyqGQTALH 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  444 YAAANCNYQCLFALVGSGASVND------LDERGCT-------PLHYAATSDTDgKCLEYLLRNDANP---GIRDKQGYN 507
Cdd:cd21882   79 IAIENRNLNLVRLLVENGADVSAratgrfFRKSPGNlfyfgelPLSLAACTNQE-EIVRLLLENGAQPaalEAQDSLGNT 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  508 AVHysaayghrlCLQLIASETPLDVLMETSGTDMLsdsdnratispLHLAAYHGHHQALEvlvqslldlDVRNSSGRTPL 587
Cdd:cd21882  158 VLH---------ALVLQADNTPENSAFVCQMYNLL-----------LSYGAHLDPTQQLE---------EIPNHQGLTPL 208

                        250
                 ....*....|
gi 63100468  588 DLAAFKGHVE 597
Cdd:cd21882  209 KLAAVEGKIV 218

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

377-493

1.30e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 46.04 E-value: 1.30e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   377 HLAALSGFSDccrKLLSSGFDIDTPDDFGRTCLHAA-------AAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANC 449
Cdd:PTZ00322   50 HLEALEATEN---KDATPDHNLTTEEVIDPVVAHMLtvelcqlAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANG 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 63100468   450 NYQCLFALVGSGASVNDLDERGCTPLHYAATSDTdGKCLEYLLR 493
Cdd:PTZ00322  127 HVQVVRVLLEFGADPTLLDKDGKTPLELAEENGF-REVVQLLSR 169

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

639-748

1.31e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 46.04 E-value: 1.31e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   639 NAEPQNAVDiqdgngQTPL-MLSV------LNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAK 711
Cdd:PTZ00322   67 NLTTEEVID------PVVAhMLTVelcqlaASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGAD 140

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 63100468   712 CLLRDSRGRTPIHLSAACGHIGVLGALL---QSATSVDAN 748
Cdd:PTZ00322  141 PTLLDKDGKTPLELAEENGFREVVQLLSrhsQCHFELGAN 180

PHA02798

ankyrin-like protein; Provisional

646-866

1.95e-04

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 45.21 E-value: 1.95e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   646 VDIQDGNGQTPL--MLSVL---NGHTDCVYSLLNKGANVDAKDKWGRTA----LHRGAVTgHEECVDALLQHGAKCLLRD 716
Cdd:PHA02798   64 VNGLDNEYSTPLctILSNIkdyKHMLDIVKILIENGADINKKNSDGETPlyclLSNGYIN-NLEILLFMIENGADTTLLD 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   717 SRGRTPIHLSAACGH---IGVLGALLQSAtsVDANpAVVDNHGYTALHwaCYNGHE------TCVELLLEQDV----FQK 783
Cdd:PHA02798  143 KDGFTMLQVYLQSNHhidIEIIKLLLEKG--VDIN-THNNKEKYDTLH--CYFKYNidridaDILKLFVDNGFiinkENK 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   784 IDGNAFSPLHCAVINDNEGAAEMLIDSLGASI-VNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMM 862
Cdd:PHA02798  218 SHKKKFMEYLNSLLYDNKRFKKNILDFIFSYIdINQVDELGFNPLYYSVSHNNRKIFEYLLQLGGDINIITELGNTCLFT 297


                  ....
gi 63100468   863 AAEN 866
Cdd:PHA02798  298 AFEN 301

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

140-280

2.74e-04

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 45.13 E-value: 2.74e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  140 GRTALHHAAFSGHGEMVKLLLSRGANINA------FDKKDRraiHWAAYMGHievvkllvshgaevtckdkksyTPLHAA 213
Cdd:cd22194  141 GQTALNIAIERRQGDIVKLLIAKGADVNAhakgvfFNPKYK---HEGFYFGE----------------------TPLALA 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  214 ASSGMISVVKYLLDlgvdmNEPNAY------GNTPLH----VA-CYNGQDVVVNELIDC------GANVNQ-KNEKGFTP 275
Cdd:cd22194  196 ACTNQPEIVQLLME-----KESTDItsqdsrGNTVLHalvtVAeDSKTQNDFVKRMYDMillkseNKNLETiRNNEGLTP 270


                 ....*
gi 63100468  276 LHFAA 280
Cdd:cd22194  271 LQLAA 275

PHA02876

ankyrin repeat protein; Provisional

670-969

3.12e-04

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 44.67 E-value: 3.12e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   670 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCL-LRDSRGRTPIHLsaacghIGVLGALLQSATSVDAN 748
Cdd:PHA02876   25 YDLHKHGANQCENESIPFTAIHQALQLRQIDIVEEIIQQNPELIyITDHKCHSTLHT------ICIIPNVMDIVISLTLD 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   749 PAVVDNHGYTALHWACYNGHETCVELLLEqdvfqKIDGNafsplhcavindnegaaEMLIDSLGASIVNATDSKGRTPlh 828
Cdd:PHA02876   99 CDIILDIKYASIILNKHKLDEACIHILKE-----AISGN-----------------DIHYDKINESIEYMKLIKERIQ-- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   829 aaafTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVSSAsADLTLQDKSKNTALHLACGKGH------ 902
Cdd:PHA02876  155 ----QDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYG-ADVNIIALDDLSVLECAVDSKNidtika 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   903 --------ETSALLILEKITDRNL------------INATNAALQTPLHVAARN-GLTMVVQELLGKGASVLAVDENGYT 961
Cdd:PHA02876  230 iidnrsniNKNDLSLLKAIRNEDLetslllydagfsVNSIDDCKNTPLHHASQApSLSRLVPKLLERGADVNAKNIKGET 309


                  ....*...
gi 63100468   962 PALACAPN 969
Cdd:PHA02876  310 PLYLMAKN 317

Ank_5

Ankyrin repeats (many copies);

32-81

3.18e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.64 E-value: 3.18e-04

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468     32 EDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRA 81
Cdd:pfam13857    7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank_5

Ankyrin repeats (many copies);

540-590

3.41e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.64 E-value: 3.41e-04

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 63100468    540 DMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 590
Cdd:pfam13857    6 PIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

652-684

3.59e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.81 E-value: 3.59e-04

                           10        20        30
                   ....*....|....*....|....*....|....
gi 63100468    652 NGQTPLMLSVL-NGHTDCVYSLLNKGANVDAKDK 684
Cdd:pfam00023    1 DGNTPLHLAAGrRGNLEIVKLLLSKGADVNARDK 34

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

207-234

3.62e-04

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 3.62e-04

                            10        20
                    ....*....|....*....|....*...
gi 63100468     207 YTPLHAAASSGMISVVKYLLDLGVDMNE 234
Cdd:smart00248    3 RTPLHLAAENGNLEVVKLLLDKGADINA 30

PHA02989

ankyrin repeat protein; Provisional

219-478

3.65e-04

ankyrin repeat protein; Provisional

Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 44.35 E-value: 3.65e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   219 ISVVKYLLDLGVDMNEpnAYGNTPLHVACYNGQDV---VVNELIDCGANVNQKnekGF--TPL-----HFAAASTHGALC 288
Cdd:PHA02989   16 KNALEFLLRTGFDVNE--EYRGNSILLLYLKRKDVkikIVKLLIDNGADVNYK---GYieTPLcavlrNREITSNKIKKI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   289 LELLVGNGADVNMKSKDGKTPLhMTALHG---------RFsrsqtIIQSGA-VIDCEDKNGNTPLHIaarYGHELLINT- 357
Cdd:PHA02989   91 VKLLLKFGADINLKTFNGVSPI-VCFIYNsninncdmlRF-----LLSKGInVNDVKNSRGYNLLHM---YLESFSVKKd 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   358 ----LITSGADT-AKRGIHGMFPLHLAALSGFS----DCCRKLLSSGFDIDTPDDFGRTCLHAAAagGNLECLNLLLNTG 428
Cdd:PHA02989  162 vikiLLSFGVNLfEKTSLYGLTPMNIYLRNDIDvisiKVIKYLIKKGVNIETNNNGSESVLESFL--DNNKILSKKEFKV 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 63100468   429 ADF-------NKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYA 478
Cdd:PHA02989  240 LNFilkyikiNKKDKKGFNPLLISAKVDNYEAFNYLLKLGDDIYNVSKDGDTVLTYA 296

Ank_5

Ankyrin repeats (many copies);

65-114

3.87e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.25 E-value: 3.87e-04

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468     65 ARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIA 114
Cdd:pfam13857    7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank_5

Ankyrin repeats (many copies);

159-213

4.28e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.25 E-value: 4.28e-04

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    159 LLSRG-ANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 213
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

377-471

4.59e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 44.12 E-value: 4.59e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   377 HLAAlSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA 456
Cdd:PTZ00322   88 QLAA-SGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQL 166

                          90
                  ....*....|....*
gi 63100468   457 LVGSGASVNDLDERG 471
Cdd:PTZ00322  167 LSRHSQCHFELGANA 181

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

470-503

4.88e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.42 E-value: 4.88e-04

                           10        20        30
                   ....*....|....*....|....*....|....
gi 63100468    470 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 503
Cdd:pfam00023    1 DGNTPLHLAAGRRGNLEIVKLLLSKGADVNARDK 34

PHA02859

ankyrin repeat protein; Provisional

428-510

5.90e-04

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 42.50 E-value: 5.90e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   428 GADFNKKDK-FGRSPLHYAAA---NCNYQCLFALVGSGASVNDLDERGCTPLH-YAATSDTDGKCLEYLLRNDANPGIRD 502
Cdd:PHA02859   76 GADVNFKTRdNNLSALHHYLSfnkNVEPEILKILIDSGSSITEEDEDGKNLLHmYMCNFNVRINVIKLLIDSGVSFLNKD 155


                  ....*...
gi 63100468   503 KQGYNAVH 510
Cdd:PHA02859  156 FDNNNILY 163

PHA02884

ankyrin repeat protein; Provisional

221-315

6.37e-04

ankyrin repeat protein; Provisional

Pssm-ID: 165212 [Multi-domain] Cd Length: 300 Bit Score: 43.05 E-value: 6.37e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   221 VVKYLLDLGVDMNEP-----NAYgNTPLHVACYNGQDVVVNELIDCGANVNQ-KNEKGFTPLHFAAasTHGAL-CLELLV 293
Cdd:PHA02884   48 IIDAILKLGADPEAPfplseNSK-TNPLIYAIDCDNDDAAKLLIRYGADVNRyAEEAKITPLYISV--LHGCLkCLEILL 124

                          90       100
                  ....*....|....*....|..
gi 63100468   294 GNGADVNMKSKDGKTPLHMTAL 315
Cdd:PHA02884  125 SYGADINIQTNDMVTPIELALM 146

PHA02884

ankyrin repeat protein; Provisional

55-195

6.89e-04

ankyrin repeat protein; Provisional

Pssm-ID: 165212 [Multi-domain] Cd Length: 300 Bit Score: 43.05 E-value: 6.89e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    55 EIIELLILSGARVNAK----DSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQ-TPLHIAAANKAVKCAESLVPL 129
Cdd:PHA02884   47 DIIDAILKLGADPEAPfplsENSKTNPLIYAIDCDNDDAAKLLIRYGADVNRYAEEAKiTPLYISVLHGCLKCLEILLSY 126

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468   130 LSNVNVSDRAGRTALHHAAFSGHGEMVKLLlsRGANINAFDKKDRRaihwaaYMGHIEVVKLLVSH 195
Cdd:PHA02884  127 GADINIQTNDMVTPIELALMICNNFLAFMI--CDNEISNFYKHPKK------ILINFDILKILVSH 184

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

271-304

8.88e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 37.65 E-value: 8.88e-04

                           10        20        30
                   ....*....|....*....|....*....|....
gi 63100468    271 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 304
Cdd:pfam00023    1 DGNTPLHLAAGRRGNLEIVKLLLSKGADVNARDK 34

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

238-266

9.21e-04

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 37.62 E-value: 9.21e-04

                           10        20
                   ....*....|....*....|....*....
gi 63100468    238 YGNTPLHVACYNGQDVVVNELIDCGANVN 266
Cdd:pfam13606    1 DGNTPLHLAARNGRLEIVKLLLENGADIN 29

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

822-853

9.24e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 37.65 E-value: 9.24e-04

                           10        20        30
                   ....*....|....*....|....*....|...
gi 63100468    822 KGRTPLHAAA-FTDHVECLQLLLSQNAQVNSAD 853
Cdd:pfam00023    1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARD 33

TRPV1-4

cd22193

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are ...

756-946

9.38e-04

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are thermo-sensing channels that function directly in temperature-sensing and nociception; they share substantial structural and functional properties. Transient Receptor Potential (TRP) ion channels activated by temperature (thermo TRPs) are important molecular players in acute, inflammatory, and chronic pain states. So far, 11 TRP channels in mammalian cells have been identified as thermosensitive TRP (thermo-TRP) channels. TRPV1-4 channels are activated by different heat temperatures, for example, TRPV1 and TRPV2 are activated by high temperatures (>43C and >55C, respectively). TRPV1-4 belong to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.

Pssm-ID: 411977 [Multi-domain] Cd Length: 607 Bit Score: 43.25 E-value: 9.38e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  756 GYTALHWACYNGHETCVELLLEQ--DVFQKIDGNAFSPlhcavinDNEGAAEMLidslgasivnatdskGRTPLHAAAFT 833
Cdd:cd22193   76 GQTALHIAIERRQGDIVALLVENgaDVHAHAKGRFFQP-------KYQGEGFYF---------------GELPLSLAACT 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  834 DHVECLQLLLS---QNAQVNSADSTGKT---PLMMAAENGQTNTveMLVSSASaDLTLQdkskntalhlACGKGHETSAl 907
Cdd:cd22193  134 NQPDIVQYLLEnehQPADIEAQDSRGNTvlhALVTVADNTKENT--KFVTRMY-DMILI----------RGAKLCPTVE- 199

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 63100468  908 liLEKITDRNLInatnaalqTPLHVAARNGLTMVVQELL 946
Cdd:cd22193  200 --LEEIRNNDGL--------TPLQLAAKMGKIEILKYIL 228

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

338-364

1.07e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.57 E-value: 1.07e-03

                            10        20
                    ....*....|....*....|....*..
gi 63100468     338 NGNTPLHIAARYGHELLINTLITSGAD 364
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGAD 27

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

618-724

1.09e-03

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 42.94 E-value: 1.09e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  618 RTPIHAAATN---GHSECLRLLIgNAEPQNAVDIQDGN---------GQTPLMLSVLNGHTDCVYSLLNKGANVDAK--- 682
Cdd:cd21882   27 KTCLHKAALNlndGVNEAIMLLL-EAAPDSGNPKELVNapctdefyqGQTALHIAIENRNLNLVRLLVENGADVSARatg 105

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 63100468  683 ---DKWGRTALHRG-------AVTGHEECVDALLQHGAK---CLLRDSRGRTPIH 724
Cdd:cd21882  106 rffRKSPGNLFYFGelplslaACTNQEEIVRLLLENGAQpaaLEAQDSLGNTVLH 160

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

755-777

1.21e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.18 E-value: 1.21e-03

                            10        20
                    ....*....|....*....|...
gi 63100468     755 HGYTALHWACYNGHETCVELLLE 777
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLD 23

TRPV1

cd22196

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1; Vanilloid receptor 1 ...

172-282

1.25e-03

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1; Vanilloid receptor 1 (TRPV1), a capsaicin (vanilloid) receptor, is the founding member of the vanilloid TRP subfamily (TRPV). In humans, it is expressed in the brain, kidney, pancreas, testis, uterus, spleen, stomach, small intestine, lung and liver. TRPV1 has been implicated to have function in thermo-sensation (heat), autonomic thermoregulation, nociception, food intake regulation, and multiple functions in the gastrointestinal (GI) tract. The receptor has also been involved in growth cone guidance, long-term depression, endocannabinoid signaling and osmosensing in the central nervous system. TRPV1 is up regulated in several human pathological conditions including vulvodynia, GI inflammation, Crohn's disease and ulcerative colitis. TRPV1 knock-out mice exhibit impaired sensation to thermal-mechanical acute pain. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.

Pssm-ID: 411980 [Multi-domain] Cd Length: 649 Bit Score: 42.87 E-value: 1.25e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  172 KDRRAIHWAAYMGHIEVVKLLVSHGAEVTC-------KDKKSYT-------PLHAAASSGMISVVKYLLD---LGVDMNE 234
Cdd:cd22196   93 KGQTALHIAIERRNMHLVELLVQNGADVHArasgeffKKKKGGPgfyfgelPLSLAACTNQLDIVKFLLEnphSPADISA 172

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63100468  235 PNAYGNTPLHVACYNGQDVVVN---------ELIDCGANVNQK-------NEKGFTPLHFAAAS 282
Cdd:cd22196  173 RDSMGNTVLHALVEVADNTPENtkfvtkmynEILILGAKIRPLlkleeitNKKGLTPLKLAAKT 236

Ank_5

Ankyrin repeats (many copies);

429-478

1.33e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 37.71 E-value: 1.33e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468    429 ADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYA 478
Cdd:pfam13857    7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

PHA02736

Viral ankyrin protein; Provisional

137-247

1.39e-03

Viral ankyrin protein; Provisional

Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 40.24 E-value: 1.39e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   137 DRAGRTALHHaaFSGHGEMVKLLLSRGANINA-------FDKKDRRAIHWAAYMGHI---EVVKLLVSHGAEVTCKDKK- 205
Cdd:PHA02736   14 DIEGENILHY--LCRNGGVTDLLAFKNAISDEnrylvleYNRHGKQCVHIVSNPDKAdpqEKLKLLMEWGADINGKERVf 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 63100468   206 SYTPLHAAASSGMISVVKYLLDL-GVDMNEPNAYGNTPLHVAC 247
Cdd:PHA02736   92 GNTPLHIAVYTQNYELATWLCNQpGVNMEILNYAFKTPYYVAC 134

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

618-724

1.53e-03

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 42.44 E-value: 1.53e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  618 RTPIHAAATNGhseCLRLLIgNAEPQNavdiQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK------------- 684
Cdd:cd22194  114 RILLAFAEENG---ILDRFI-NAEYTE----EAYEGQTALNIAIERRQGDIVKLLIAKGADVNAHAKgvffnpkykhegf 185

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 63100468  685 -WGRTALHRGAVTGHEECVDALLQHGAKCL-LRDSRGRTPIH 724
Cdd:cd22194  186 yFGETPLALAACTNQPEIVQLLMEKESTDItSQDSRGNTVLH 227

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

176-201

1.78e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.80 E-value: 1.78e-03

                            10        20
                    ....*....|....*....|....*.
gi 63100468     176 AIHWAAYMGHIEVVKLLVSHGAEVTC 201
Cdd:smart00248    5 PLHLAAENGNLEVVKLLLDKGADINA 30

Ank_5

Ankyrin repeats (many copies);

672-725

2.05e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 37.33 E-value: 2.05e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 63100468    672 LLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL 725
Cdd:pfam13857    2 LEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55

PHA02716

CPXV016; CPX019; EVM010; Provisional

566-760

2.07e-03

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 42.21 E-value: 2.07e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   566 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVeCVDVL---INQGASILVKdYVLKRTPIHAAATNghseclrllIGNAEP 642
Cdd:PHA02716  195 LEWLCNNGVNVNLQNNHLITPLHTYLITGNV-CASVIkkiIELGGDMDMK-CVNGMSPIMTYIIN---------IDNINP 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   643 Q--NA-VDIQDGNGQT--PLMLSVL-----NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGH--EECVDALLQHGA 710
Cdd:PHA02716  264 EitNIyIESLDGNKVKniPMILHSYitlarNIDISVVYSFLQPGVKLHYKDSAGRTCLHQYILRHNisTDIIKLLHEYGN 343

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 63100468   711 KCLLRDSRGRTPIH--LSAACG------------HIGVLGALLQSATSVDAnpavVDNHGYTAL 760
Cdd:PHA02716  344 DLNEPDNIGNTVLHtyLSMLSVvnildpetdndiRLDVIQCLISLGADITA----VNCLGYTPL 403

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

42-71

2.11e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.50 E-value: 2.11e-03

                           10        20        30
                   ....*....|....*....|....*....|.
gi 63100468     42 RTPLHAAAY-LGDAEIIELLILSGARVNAKD 71
Cdd:pfam00023    3 NTPLHLAAGrRGNLEIVKLLLSKGADVNARD 33

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

176-204

2.22e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.50 E-value: 2.22e-03

                           10        20        30
                   ....*....|....*....|....*....|
gi 63100468    176 AIHWAAYM-GHIEVVKLLVSHGAEVTCKDK 204
Cdd:pfam00023    5 PLHLAAGRrGNLEIVKLLLSKGADVNARDK 34

Ank_5

Ankyrin repeats (many copies);

917-962

2.52e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 2.52e-03

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 63100468    917 NLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTP 962
Cdd:pfam13857    7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTA 52

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

583-609

2.58e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.41 E-value: 2.58e-03

                            10        20
                    ....*....|....*....|....*..
gi 63100468     583 GRTPLDLAAFKGHVECVDVLINQGASI 609
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGADI 28

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

76-105

2.70e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.50 E-value: 2.70e-03

                           10        20        30
                   ....*....|....*....|....*....|.
gi 63100468     76 TPLHRAVASC-SEEAVQILLKHSADVNARDK 105
Cdd:pfam00023    4 TPLHLAAGRRgNLEIVKLLLSKGADVNARDK 34

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

822-850

2.74e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.41 E-value: 2.74e-03

                            10        20
                    ....*....|....*....|....*....
gi 63100468     822 KGRTPLHAAAFTDHVECLQLLLSQNAQVN 850
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

583-613

2.81e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.11 E-value: 2.81e-03

                           10        20        30
                   ....*....|....*....|....*....|..
gi 63100468    583 GRTPLDLAAFK-GHVECVDVLINQGASILVKD 613
Cdd:pfam00023    2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNARD 33

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

344-416

2.82e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 41.81 E-value: 2.82e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 63100468   344 HIAARyGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGG 416
Cdd:PTZ00322   88 QLAAS-GDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159

Ank_5

Ankyrin repeats (many copies);

132-171

3.09e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 3.09e-03

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 63100468    132 NVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDK 171
Cdd:pfam13857    8 DLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDE 47

Ank_5

Ankyrin repeats (many copies);

462-511

3.13e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 3.13e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 63100468    462 ASVNDLDERGCTPLHYAAtSDTDGKCLEYLLRNDANPGIRDKQGYNAVHY 511
Cdd:pfam13857    7 IDLNRLDGEGYTPLHVAA-KYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55

Ank_5

Ankyrin repeats (many copies);

812-863

3.16e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 3.16e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 63100468    812 GASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMA 863
Cdd:pfam13857    5 GPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

PHA02798

ankyrin-like protein; Provisional

805-920

3.70e-03

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 40.97 E-value: 3.70e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   805 EMLIDsLGASiVNATDSKGRTPL-----HAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQTNTVEMLVS-- 877
Cdd:PHA02798   55 KLFIN-LGAN-VNGLDNEYSTPLctilsNIKDYKHMLDIVKILIENGADINKKNSDGETPLYCLLSNGYINNLEILLFmi 132

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 63100468   878 SASADLTLQDKSKNTALHLACGKGHETSALLI---LEKITDRNLIN 920
Cdd:PHA02798  133 ENGADTTLLDKDGFTMLQVYLQSNHHIDIEIIkllLEKGVDINTHN 178

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

652-681

3.86e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 35.64 E-value: 3.86e-03

                            10        20        30
                    ....*....|....*....|....*....|
gi 63100468     652 NGQTPLMLSVLNGHTDCVYSLLNKGANVDA 681
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30

PHA02946

ankyin-like protein; Provisional

222-378

4.15e-03

ankyin-like protein; Provisional

Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 40.81 E-value: 4.15e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   222 VKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVN 300
Cdd:PHA02946   55 VEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEVIeRINLLVQYGAKIN 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   301 MK-SKDGKTPL----------------------------------HMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHI 345
Cdd:PHA02946  135 NSvDEEGCGPLlactdpservfkkimsigfearivdkfgknhihrHLMSDNPKASTISWMMKLGISPSKPDHDGNTPLHI 214

                         170       180       190
                  ....*....|....*....|....*....|....
gi 63100468   346 A-ARYGHELLINTLITSGADTAKRGIHGMFPLHL 378
Cdd:PHA02946  215 VcSKTVKNVDIINLLLPSTDVNKQNKFGDSPLTL 248

Ank_4

Ankyrin repeats (many copies);

891-946

4.45e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.48 E-value: 4.45e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 63100468    891 NTALHLACGKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELL 946
Cdd:pfam13637    2 LTALHAAAASGHLELLRLLLEKGAD---INAVDGNGETALHFAASNGNVEVLKLLL 54

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

391-571

4.55e-03

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 40.83 E-value: 4.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    391 LLSSGFDIDTpddfGRTCLHAA-----------------AAGGNLECLNLLLNTGADFNkkdkFGRSPLHYAAANCNYQC 453
Cdd:TIGR00870   72 LLNLSCRGAV----GDTLLHAIsleyvdaveaillhllaAFRKSGPLELANDQYTSEFT----PGITALHLAAHRQNYEI 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    454 LFALVGSGASVN--------------DLDERGCTPLH-YAATSDTDgkCLEYLLRNDANPGIRDKQGYNAVH-------Y 511
Cdd:TIGR00870  144 VKLLLERGASVParacgdffvksqgvDSFYHGESPLNaAACLGSPS--IVALLSEDPADILTADSLGNTLLHllvmeneF 221

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 63100468    512 SAAYGH--RLCLQLIasetpLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQ 571
Cdd:TIGR00870  222 KAEYEElsCQMYNFA-----LSLLDKLRDSKELEVILNHQGLTPLKLAAKEGRIVLFRLKLA 278

Ank_4

Ankyrin repeats (many copies);

928-979

4.68e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.10 E-value: 4.68e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 63100468    928 TPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALI 979
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV1-4

cd22193

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are ...

140-282

4.83e-03

Pssm-ID: 411977 [Multi-domain] Cd Length: 607 Bit Score: 40.93 E-value: 4.83e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  140 GRTALHHAAFSGHGEMVKLLLSRGANINA------FDKKDRRAihwAAYMGHievvkllvshgaevtckdkksyTPLHAA 213
Cdd:cd22193   76 GQTALHIAIERRQGDIVALLVENGADVHAhakgrfFQPKYQGE---GFYFGE----------------------LPLSLA 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468  214 ASSGMISVVKYLLD---LGVDMNEPNAYGNTPLHVACYNGQDVVVN---------ELIDCGANVNQ-------KNEKGFT 274
Cdd:cd22193  131 ACTNQPDIVQYLLEnehQPADIEAQDSRGNTVLHALVTVADNTKENtkfvtrmydMILIRGAKLCPtveleeiRNNDGLT 210


                 ....*...
gi 63100468  275 PLHFAAAS 282
Cdd:cd22193  211 PLQLAAKM 218

Ank_4

Ankyrin repeats (many copies);

858-903

4.96e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.10 E-value: 4.96e-03

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 63100468    858 TPLMMAAENGQTNTVEMLVSSaSADLTLQDKSKNTALHLACGKGHE 903
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEK-GADINAVDGNGETALHFAASNGNV 47

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

15-79

4.99e-03

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 40.77 E-value: 4.99e-03

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 63100468   15 AIFNGDPDEVRALIFKKEDVN--------FQDNEKRT------PLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLH 79
Cdd:cd22192   96 AVVNQNLNLVRELIARGADVVspratgtfFRPGPKNLiyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLH 174

PHA02989

ankyrin repeat protein; Provisional

186-277

5.32e-03

ankyrin repeat protein; Provisional

Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 40.49 E-value: 5.32e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   186 IEVVKLLVSHGAEVtckDKKSY--TPLHAA------ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE 257
Cdd:PHA02989   50 IKIVKLLIDNGADV---NYKGYieTPLCAVlrnreiTSNKIKKIVKLLLKFGADINLKTFNGVSPIVCFIYNSNINNCDM 126

                          90       100
                  ....*....|....*....|....
gi 63100468   258 L---IDCGANVNQ-KNEKGFTPLH 277
Cdd:PHA02989  127 LrflLSKGINVNDvKNSRGYNLLH 150

PHA02859

ankyrin repeat protein; Provisional

790-895

5.82e-03

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 39.42 E-value: 5.82e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   790 SPLHCAVIND--NEGAAEMLIDSlGASIVNATDSKGRTPLHA-AAFTDHV--ECLQLLLSQNAQVNSADSTGKTPLMMAA 864
Cdd:PHA02859   53 TPIFSCLEKDkvNVEILKFLIEN-GADVNFKTRDNNLSALHHyLSFNKNVepEILKILIDSGSSITEEDEDGKNLLHMYM 131

                          90       100       110
                  ....*....|....*....|....*....|...
gi 63100468   865 ENGQTN--TVEMLVSSASADLTlQDKSKNTALH 895
Cdd:PHA02859  132 CNFNVRinVIKLLIDSGVSFLN-KDFDNNNILY 163

PHA02791

ankyrin-like protein; Provisional

97-275

6.07e-03

ankyrin-like protein; Provisional

Pssm-ID: 165154 [Multi-domain] Cd Length: 284 Bit Score: 40.03 E-value: 6.07e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468    97 SADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRagRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRA 176
Cdd:PHA02791   20 SKDAFKADVHGHSALYYAIADNNVRLVCTLLNAGALKNLLEN--EFPLHQAATLEDTKIVKILLFSGMDDSQFDDKGNTA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   177 IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSY-TPLHAAASSGMISVVKYLL-------DLGVDMnepnaygnTPLHVACY 248
Cdd:PHA02791   98 LYYAVDSGNMQTVKLFVKKNWRLMFYGKTGWkTSFYHAVMLNDVSIVSYFLseipstfDLAILL--------SCIHITIK 169

                         170       180
                  ....*....|....*....|....*..
gi 63100468   249 NGQDVVVNELIDCGANVNQKNEKGFTP 275
Cdd:PHA02791  170 NGHVDMMILLLDYMTSTNTNNSLLFIP 196

PHA02791

ankyrin-like protein; Provisional

753-921

6.23e-03

ankyrin-like protein; Provisional

Pssm-ID: 165154 [Multi-domain] Cd Length: 284 Bit Score: 40.03 E-value: 6.23e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   753 DNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFsPLH-CAVINDNEGAAEMLIDSLGASivnATDSKGRTPLHAAA 831
Cdd:PHA02791   27 DVHGHSALYYAIADNNVRLVCTLLNAGALKNLLENEF-PLHqAATLEDTKIVKILLFSGMDDS---QFDDKGNTALYYAV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   832 FTDHVECLQLLLSQNAQVNSADSTG-KTPLMMAAENGQTNTVEMLVSSASADLTLQDKSknTALHLACGKGHETSALLIL 910
Cdd:PHA02791  103 DSGNMQTVKLFVKKNWRLMFYGKTGwKTSFYHAVMLNDVSIVSYFLSEIPSTFDLAILL--SCIHITIKNGHVDMMILLL 180

                         170
                  ....*....|.
gi 63100468   911 EKITDRNLINA 921
Cdd:PHA02791  181 DYMTSTNTNNS 191

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

755-780

6.64e-03

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 35.31 E-value: 6.64e-03

                           10        20
                   ....*....|....*....|....*.
gi 63100468    755 HGYTALHWACYNGHETCVELLLEQDV 780
Cdd:pfam13606    1 DGNTPLHLAARNGRLEIVKLLLENGA 26

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

338-364

6.98e-03

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 34.93 E-value: 6.98e-03

                           10        20
                   ....*....|....*....|....*..
gi 63100468    338 NGNTPLHIAARYGHELLINTLITSGAD 364
Cdd:pfam13606    1 DGNTPLHLAARNGRLEIVKLLLENGAD 27

Ank_4

Ankyrin repeats (many copies);

473-523

8.37e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 35.71 E-value: 8.37e-03

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 63100468    473 TPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQL 523
Cdd:pfam13637    3 TALHAAAASG-HLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKL 52

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

519-602

8.55e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 40.27 E-value: 8.55e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63100468   519 LClQLIASETPLDV-LMETSGTDMLS-DSDNRatiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHV 596
Cdd:PTZ00322   86 LC-QLAASGDAVGArILLTGGADPNCrDYDGR---TPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFR 161


                  ....*.
gi 63100468   597 ECVDVL 602
Cdd:PTZ00322  162 EVVQLL 167

Ank