|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
72-507 |
8.46e-27 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 115.72 E-value: 8.46e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 72 LSLQNNQLRELPYNELSRLSGLRTLDLHSNLIT-------------------SEGLPDEAFESLNQLENF---YVAHNKL 129
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVgkipnsltnltslefltlaSNQLVGQIPRELGQMKSLkwiYLGYNNL 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 130 SVA-PQFLPR--SLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLrnTGLPPNTFHGSEAITTLSLSSNQLSYLPPS 206
Cdd:PLN00113 225 SGEiPYEIGGltSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKL--SGPIPPSIFSLQKLISLDLSDNSLSGEIPE 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 207 LPA---SLERLHL-QNNLISKVPRGALSLqTHLRELYLQHNQLtdSGLDATTFSKLSSLEYLDLSHNQLA-TVPEGL--P 279
Cdd:PLN00113 303 LVIqlqNLEILHLfSNNFTGKIPVALTSL-PRLQVLQLWSNKF--SGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLcsS 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 280 GTLTILHLGRNCIRHVEAVRLHKARGLRYLLLQHNKLgASALPKGTLRpLRALHTLHLYGNKLERVPPALPRHLQALVMp 359
Cdd:PLN00113 380 GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSF-SGELPSEFTK-LPLVYFLDISNNNLQGRINSRKWDMPSLQM- 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 360 hnhvaalgardlvsaralaeLNLAYNSLASARvhPSAFRRLRaLRSLDLAGNQLTrlpEGLPASLRS------LRLQRNQ 433
Cdd:PLN00113 457 --------------------LSLARNKFFGGL--PDSFGSKR-LENLDLSRNQFS---GAVPRKLGSlselmqLKLSENK 510
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 39645736 434 LRTLEPEQLAGLNKLRELNLTHNRLRvGDIgPGTWHELQALKVLDLSHNELSF-VPPDLPEalEELHLQANrISH 507
Cdd:PLN00113 511 LSGEIPDELSSCKKLVSLDLSHNQLS-GQI-PASFSEMPVLSQLDLSQNQLSGeIPKNLGN--VESLVQVN-ISH 580
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
172-442 |
4.49e-23 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 103.62 E-value: 4.49e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 172 NRLRNTGLPPNTfhgSEAITTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRgalSLQTHLRELYLQHNQLTDSGld 251
Cdd:PRK15370 186 KILGLTTIPACI---PEQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPA---TLPDTIQEMELSINRITELP-- 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 252 attfSKL-SSLEYLDLSHNQLATVPEGLPGTLTILHLGRNCIRHVEAvrlHKARGLRYLLLQHNKLgaSALPKgTLRPlr 330
Cdd:PRK15370 258 ----ERLpSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPA---HLPSGITHLNVQSNSL--TALPE-TLPP-- 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 331 ALHTLHLYGNKLERVPPALPRHLQALVMPHNHVAALgardlvsaralaelnlaynslaSARVHPSafrrlraLRSLDLAG 410
Cdd:PRK15370 326 GLKTLEAGENALTSLPASLPPELQVLDVSKNQITVL----------------------PETLPPT-------ITTLDVSR 376
|
250 260 270
....*....|....*....|....*....|..
gi 39645736 411 NQLTRLPEGLPASLRSLRLQRNQLRTLePEQL 442
Cdd:PRK15370 377 NALTNLPENLPAALQIMQASRNNLVRL-PESL 407
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
152-529 |
8.47e-22 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 99.92 E-value: 8.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 152 EIFPLTFGeKPALRSVYLHNNRLrNTGLPPNTFHGSEAITTLSLSSNQLS-YLPPSLPASLERLHLQNNLIS-KVPRgAL 229
Cdd:PLN00113 84 KISSAIFR-LPYIQTINLSNNQL-SGPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSgEIPN-DI 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 230 SLQTHLRELYLQHNQLTdsGLDATTFSKLSSLEYLDLSHNQL-ATVPE--GLPGTLTILHLGRN--------------CI 292
Cdd:PLN00113 161 GSFSSLKVLDLGGNVLV--GKIPNSLTNLTSLEFLTLASNQLvGQIPRelGQMKSLKWIYLGYNnlsgeipyeiggltSL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 293 RHVEAV----------RLHKARGLRYLLLQHNKLgASALPKgTLRPLRALHTLHLYGNKLERVPPALPRHLQALVMPH-- 360
Cdd:PLN00113 239 NHLDLVynnltgpipsSLGNLKNLQYLFLYQNKL-SGPIPP-SIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHlf 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 361 -NHVAALGARDLVSARALAELNLAYNSLASARvhPSAFRRLRALRSLDLAGNQLT-RLPEGLPAS--------------- 423
Cdd:PLN00113 317 sNNFTGKIPVALTSLPRLQVLQLWSNKFSGEI--PKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSgnlfklilfsnsleg 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 424 -----------LRSLRLQRNQLRTLEPEQLAGLNKLRELNLTHNRLRvGDIGPGTWhELQALKVLDLSHNELSFVPPDL- 491
Cdd:PLN00113 395 eipkslgacrsLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQ-GRINSRKW-DMPSLQMLSLARNKFFGGLPDSf 472
|
410 420 430
....*....|....*....|....*....|....*....
gi 39645736 492 -PEALEELHLQANRISHVGPEAFLSTPHLRALFLRANRL 529
Cdd:PLN00113 473 gSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKL 511
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
191-497 |
1.33e-21 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 99.00 E-value: 1.33e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 191 TTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRgalSLQTHLRELYLQHNQLTdsgldattfsklssleyldlshnq 270
Cdd:PRK15370 181 TELRLKILGLTTIPACIPEQITTLILDNNELKSLPE---NLQGNIKTLYANSNQLT------------------------ 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 271 laTVPEGLPGTLTILHLGRNCIRHVEAvrlHKARGLRYLLLQHNKLgaSALPKGTLRPLRalhTLHLYGNKLERVPPALP 350
Cdd:PRK15370 234 --SIPATLPDTIQEMELSINRITELPE---RLPSALQSLDLFHNKI--SCLPENLPEELR---YLSVYDNSIRTLPAHLP 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 351 RHLQALVMPHNHVAALGARDLVSARALAELNLAYNSLAsARVHPsafrrlrALRSLDLAGNQLTRLPEGLPASLRSLRLQ 430
Cdd:PRK15370 304 SGITHLNVQSNSLTALPETLPPGLKTLEAGENALTSLP-ASLPP-------ELQVLDVSKNQITVLPETLPPTITTLDVS 375
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 39645736 431 RNQLRTLePEQLAGlnklrelnlthnrlrvgdigpgtwhelqALKVLDLSHNELSFVPPDLPEALEE 497
Cdd:PRK15370 376 RNALTNL-PENLPA----------------------------ALQIMQASRNNLVRLPESLPHFRGE 413
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
326-562 |
1.60e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 97.31 E-value: 1.60e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 326 LRPLRALHTLHLYGNKLERVPPALPR--HLQALVMPHNHVAALGArDLVSARALAELNLAYNSLASArvhPSAFRRLRAL 403
Cdd:COG4886 109 LSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL---PEELGNLTNL 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 404 RSLDLAGNQLTRLPEGL--PASLRSLRLQRNQLRTLePEQLAGLNKLRELNLTHNRLR-VGDIGpgtwhELQALKVLDLS 480
Cdd:COG4886 185 KELDLSNNQITDLPEPLgnLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTdLPELG-----NLTNLEELDLS 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 481 HNELSFVPPDLP-EALEELHLQANRISHVGPEAFLSTPHLRALFLRANRLHMTSIAAEALQGLTHLRVVDTAENPEQVLV 559
Cdd:COG4886 259 NNQLTDLPPLANlTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLT 338
|
...
gi 39645736 560 QLP 562
Cdd:COG4886 339 TLA 341
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
72-457 |
3.57e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 96.16 E-value: 3.57e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 72 LSLQNNQLRELPYNELSRLSGLRTLDLHSNLITSEGLPDEAFESLNQLENFYVAHNKLSVAPQFLPRSLRVADLAANEvv 151
Cdd:COG4886 30 LLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 152 EIFPLTfgekpALRSVYLHNNRLRNTglpPNTFHGSEAITTLSLSSNQLSYLPPSLP--ASLERLHLQNNLISKVPRGAL 229
Cdd:COG4886 108 ELSNLT-----NLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPEELG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 230 SLqTHLRELYLQHNQLTDSGldaTTFSKLSSLEYLDLSHNQLATVPEGLPG--TLTILHLGRNCIRHVEAvrLHKARGLR 307
Cdd:COG4886 180 NL-TNLKELDLSNNQITDLP---EPLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDLPE--LGNLTNLE 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 308 YLLLQHNKLgaSALPKgtLRPLRALHTLHLYGNKLERVPPALPRHLQALVMPHNHVAALGARDLVSARALAELNLAYNSL 387
Cdd:COG4886 254 ELDLSNNQL--TDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 388 ASARVHPSAFRRLRALRSLDLAGNQLTRLPEGLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLTHNR 457
Cdd:COG4886 330 LKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAG 399
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
187-485 |
5.69e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 95.39 E-value: 5.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 187 SEAITTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRGALSLQTHLRELYLQHNQltdsgldatTFSKLSSLEYLDL 266
Cdd:COG4886 50 TLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 267 SHNQLATVPEGLPG--TLTILHLGRNCIRHVEAVrLHKARGLRYLLLQHNKLgaSALPKGtLRPLRALHTLHLYGNKLER 344
Cdd:COG4886 121 SGNQLTDLPEELANltNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQL--TDLPEE-LGNLTNLKELDLSNNQITD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 345 VPPAL--PRHLQALVMPHNHVAALGArDLVSARALAELNLAYNSLASArvhpSAFRRLRALRSLDLAGNQLTRLPEGLP- 421
Cdd:COG4886 197 LPEPLgnLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDL----PELGNLTNLEELDLSNNQLTDLPPLANl 271
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645736 422 ASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLTHNRLRVGDIGPGTWHELQALKVLDLSHNELS 485
Cdd:COG4886 272 TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
56-279 |
3.34e-20 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 94.76 E-value: 3.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 56 LDLRIFPDNITRAARHLSLQNNQLRELPYNelsrLSG-LRTLDLHSNLITS--EGLPD-------------EAFESL-NQ 118
Cdd:PRK15370 188 LGLTTIPACIPEQITTLILDNNELKSLPEN----LQGnIKTLYANSNQLTSipATLPDtiqemelsinritELPERLpSA 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 119 LENFYVAHNKLSVAPQFLPRSLRVADLAANEVVEIfpltfgekPA-LRSVYLHNNRLRNT------GLPPNtfhgseaIT 191
Cdd:PRK15370 264 LQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTL--------PAhLPSGITHLNVQSNSltalpeTLPPG-------LK 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 192 TLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRgalSLQTHLRELYLQHNQLTD--SGLDAttfsklsSLEYLDLSHN 269
Cdd:PRK15370 329 TLEAGENALTSLPASLPPELQVLDVSKNQITVLPE---TLPPTITTLDVSRNALTNlpENLPA-------ALQIMQASRN 398
|
250
....*....|
gi 39645736 270 QLATVPEGLP 279
Cdd:PRK15370 399 NLVRLPESLP 408
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
70-271 |
5.30e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 92.69 E-value: 5.30e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 70 RHLSLQNNQLRELPyNELSRLSGLRTLDLHSNLITSegLPdEAFESLNQLENFYVAHNKLSVAPQflprslrvadlaane 149
Cdd:COG4886 116 ESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTD--LP-EPLGNLTNLKSLDLSNNQLTDLPE--------------- 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 150 vvEIFPLTfgekpALRSVYLHNNRLRNTglpPNTFHGSEAITTLSLSSNQLSYLPPSLPA--SLERLHLQNNLISKVPrg 227
Cdd:COG4886 177 --ELGNLT-----NLKELDLSNNQITDL---PEPLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDLP-- 244
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 39645736 228 ALSLQTHLRELYLQHNQLTdsglDATTFSKLSSLEYLDLSHNQL 271
Cdd:COG4886 245 ELGNLTNLEELDLSNNQLT----DLPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
70-290 |
8.31e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 82.67 E-value: 8.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 70 RHLSLQNNQLRELPyNELSRLSGLRTLDLHSNLITSegLPDEaFESLNQLENFYVAHNKLSVapqflprslrvadlaane 149
Cdd:COG4886 139 KELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTD--LPEE-LGNLTNLKELDLSNNQITD------------------ 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 150 vveiFPLTFGEKPALRSVYLHNNRLRNtglPPNTFHGSEAITTLSLSSNQLSYLPP--SLPaSLERLHLQNNLISKVPrg 227
Cdd:COG4886 197 ----LPEPLGNLTNLEELDLSGNQLTD---LPEPLANLTNLETLDLSNNQLTDLPElgNLT-NLEELDLSNNQLTDLP-- 266
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 39645736 228 ALSLQTHLRELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATVPEGLPGTLTILHLGRN 290
Cdd:COG4886 267 PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
190-417 |
1.25e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 75.98 E-value: 1.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 190 ITTLSLSSNQLSYLP-PSLPASLERLHLQNNLISKVPrgALSLQTHLRELYLQHNQLTdsgldattfsklsSLEYLDLSH 268
Cdd:cd21340 4 ITHLYLNDKNITKIDnLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIE-------------KIENLENLV 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 269 NqlatvpeglpgtLTILHLGRNCIRHVEAvrLHKARGLRYLLLQHNKLGAsalpkgtlrplralhtlhlyGNKLE---RV 345
Cdd:cd21340 69 N------------LKKLYLGGNRISVVEG--LENLTNLEELHIENQRLPP--------------------GEKLTfdpRS 114
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 39645736 346 PPALPRHLQALVMPHNHVAALgaRDLVSARALAELNLAYNSLASARVHPSAFRRLRALRSLDLAGNQLTRLP 417
Cdd:cd21340 115 LAALSNSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
309-529 |
4.96e-15 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 78.20 E-value: 4.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 309 LLLQHNKLgaSALPKGtlrpLRA-LHTLHLYGNKLERVPPALPRHLQALVMPHNHVAALGARdlvsaralaelnlaynsl 387
Cdd:PRK15370 204 LILDNNEL--KSLPEN----LQGnIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPER------------------ 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 388 asarvHPSAfrrlraLRSLDLAGNQLTRLPEGLPASLRSLRLQRNQLRTLePEQLAglNKLRELNLTHNRLRV--GDIGP 465
Cdd:PRK15370 260 -----LPSA------LQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTL-PAHLP--SGITHLNVQSNSLTAlpETLPP 325
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645736 466 GtwhelqaLKVLDLSHNELSFVPPDLPEALEELHLQANRIShVGPEAFlsTPHLRALFLRANRL 529
Cdd:PRK15370 326 G-------LKTLEAGENALTSLPASLPPELQVLDVSKNQIT-VLPETL--PPTITTLDVSRNAL 379
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
70-300 |
1.46e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 72.66 E-value: 1.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 70 RHLSLQNNQLRELPyNELSRLSGLRTLDLHSNLITSegLPDEaFESLNQLENFYVAHNKLSVAPQFLPR--SLRVADLAA 147
Cdd:COG4886 162 KSLDLSNNQLTDLP-EELGNLTNLKELDLSNNQITD--LPEP-LGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSN 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 148 NEVVEIFPLtfGEKPALRSVYLHNNRLrnTGLPPNTfhGSEAITTLSLSSNQLSYL------PPSLPASLERLHLQNNLI 221
Cdd:COG4886 238 NQLTDLPEL--GNLTNLEELDLSNNQL--TDLPPLA--NLTNLKTLDLSNNQLTDLklkeleLLLGLNSLLLLLLLLNLL 311
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 39645736 222 SKVPRGALSLQTHLRELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATVPEGLPGTLTILHLGRNCIRHVEAVRL 300
Cdd:COG4886 312 ELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
138-459 |
1.97e-13 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 72.52 E-value: 1.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 138 RSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLRNTGLPPNTFHGSEAITTLSLSSNQLSY-LPPSLPASLERLhl 216
Cdd:COG5238 64 RFEGQGDPGLNPVALEKAAEAFPTQLLVVDWEGAEEVSPVALAETATAVATPPPDLRRIMAKTLEdSLILYLALPRRI-- 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 217 qnNLISKVPRGALSLQTHLRelYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATvpEGL---------PGTLTILHL 287
Cdd:COG5238 142 --NLIQVLKDPLGGNAVHLL--GLAARLGLLAAISMAKALQNNSVETVYLGCNQIGD--EGIeelaealtqNTTVTTLWL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 288 GRNCIRHVEAVRLHKA----RGLRYLLLQHNKL---GASALPKgTLRPLRALHTLHLYGNKL-----ERVPPALPR--HL 353
Cdd:COG5238 216 KRNPIGDEGAEILAEAlkgnKSLTTLDLSNNQIgdeGVIALAE-ALKNNTTVETLYLSGNQIgaegaIALAKALQGntTL 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 354 QALVMPHNHVAALGARDLVSA----RALAELNLAYNSL--ASARVHPSAFRRLRALRSLDLAGNQLT--------RLPEG 419
Cdd:COG5238 295 TSLDLSVNRIGDEGAIALAEGlqgnKTLHTLNLAYNGIgaQGAIALAKALQENTTLHSLDLSDNQIGdegaialaKYLEG 374
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 39645736 420 LPaSLRSLRLQRNQLRTLEPEQLAGL---NKLRELNLTHNRLR 459
Cdd:COG5238 375 NT-TLRELNLGKNNIGKQGAEALIDAlqtNRLHTLILDGNLIG 416
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
171-438 |
6.63e-12 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 68.26 E-value: 6.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 171 NNRLRNTGLPPNtfhgseaITTLSLSSNQLSYLPpSLPASLERLHLQNNLISKVPrgalSLQTHLRELYLQHNQLTDSGL 250
Cdd:PRK15387 232 NNLTSLPALPPE-------LRTLEVSGNQLTSLP-VLPPGLLELSIFSNPLTHLP----ALPSGLCKLWIFGNQLTSLPV 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 251 DATTFSKLSsleyldLSHNQLATVPeGLPGTLTILHLGRNCIRHVEAVrlhkARGLRYLLLQHNKLGA-SALPKgtlrpl 329
Cdd:PRK15387 300 LPPGLQELS------VSDNQLASLP-ALPSELCKLWAYNNQLTSLPTL----PSGLQELSVSDNQLASlPTLPS------ 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 330 rALHTLHLYGNKLERVPpALPRHLQALVMPHNHVAALGardlVSARALAELNLAYNSLASARVHPSAfrrlraLRSLDLA 409
Cdd:PRK15387 363 -ELYKLWAYNNRLTSLP-ALPSGLKELIVSGNRLTSLP----VLPSELKELMVSGNRLTSLPMLPSG------LLSLSVY 430
|
250 260 270
....*....|....*....|....*....|...
gi 39645736 410 GNQLTRLPEGLP--ASLRSLRLQRNQL--RTLE 438
Cdd:PRK15387 431 RNQLTRLPESLIhlSSETTVNLEGNPLseRTLQ 463
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
162-314 |
4.67e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 62.88 E-value: 4.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 162 PALRSVYLHNNRLRN-TGLPPNTfhgseAITTLSLSSNQLSYLPP--SLPaSLERLHLQNNLISKVprGALSLQTHLREL 238
Cdd:cd21340 24 KNLKVLYLYDNKITKiENLEFLT-----NLTHLYLQNNQIEKIENleNLV-NLKKLYLGGNRISVV--EGLENLTNLEEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 239 YLQHNQLtDSG----LDATTFSKLS-SLEYLDLSHNQLATVpEGLPG--TLTILHLGRNCIRHVEAVR--LHKARGLRYL 309
Cdd:cd21340 96 HIENQRL-PPGekltFDPRSLAALSnSLRVLNISGNNIDSL-EPLAPlrNLEQLDASNNQISDLEELLdlLSSWPSLREL 173
|
....*
gi 39645736 310 LLQHN 314
Cdd:cd21340 174 DLTGN 178
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
161-345 |
1.26e-10 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 62.76 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 161 KPALRSVYLHNNRL----RNTGLPPNTFHGSEAITTLSLSSNQLSY-LPPSLPA-----SLERLHLQNNLISK-----VP 225
Cdd:cd00116 50 QPSLKELCLSLNETgripRGLQSLLQGLTKGCGLQELDLSDNALGPdGCGVLESllrssSLQELKLNNNGLGDrglrlLA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 226 RGALSLQTHLRELYLQHNQLTDSGLDAT--TFSKLSSLEYLDLSHNQL-----ATVPEGLPGT--LTILHLGRNCIRHVE 296
Cdd:cd00116 130 KGLKDLPPALEKLVLGRNRLEGASCEALakALRANRDLKELNLANNGIgdagiRALAEGLKANcnLEVLDLNNNGLTDEG 209
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 39645736 297 AVRLHKA----RGLRYLLLQHNKL---GASALPKGTLRPLRALHTLHLYGNKLERV 345
Cdd:cd00116 210 ASALAETlaslKSLEVLNLGDNNLtdaGAAALASALLSPNISLLTLSLSCNDITDD 265
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
193-475 |
1.69e-10 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 64.03 E-value: 1.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 193 LSLSSNQLSYLPPSLPASLERLHLQNNLISKVPrgalSLQTHLRELYLQHNQLTDSGLDATTFSKLSsleyldLSHNQLA 272
Cdd:PRK15387 206 LNVGESGLTTLPDCLPAHITTLVIPDNNLTSLP----ALPPELRTLEVSGNQLTSLPVLPPGLLELS------IFSNPLT 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 273 TVPeGLPGTLTILHLGRNCIRHVEAVrlhkARGLRYLLLQHNKLGA-SALPKgtlrplrALHTLHLYGNKLERVpPALPR 351
Cdd:PRK15387 276 HLP-ALPSGLCKLWIFGNQLTSLPVL----PPGLQELSVSDNQLASlPALPS-------ELCKLWAYNNQLTSL-PTLPS 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 352 HLQALVMPHNHVAALGA------------RDLVSARA----LAELNLAYNSLASARVHPSafrrlrALRSLDLAGNQLTR 415
Cdd:PRK15387 343 GLQELSVSDNQLASLPTlpselyklwaynNRLTSLPAlpsgLKELIVSGNRLTSLPVLPS------ELKELMVSGNRLTS 416
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 416 LPEgLPASLRSLRLQRNQLRTLePEQLAGLNKLRELNLTHNrlrvgdigPGTWHELQALK 475
Cdd:PRK15387 417 LPM-LPSGLLSLSVYRNQLTRL-PESLIHLSSETTVNLEGN--------PLSERTLQALR 466
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
210-271 |
1.05e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.45 E-value: 1.05e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 39645736 210 SLERLHLQNNLISKVPRGALSLQTHLRELYLQHNQLTdsGLDATTFSKLSSLEYLDLSHNQL 271
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
423-484 |
2.84e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.30 E-value: 2.84e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 39645736 423 SLRSLRLQRNQLRTLEPEQLAGLNKLRELNLTHNRLRVgdIGPGTWHELQALKVLDLSHNEL 484
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
401-458 |
6.33e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.14 E-value: 6.33e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 39645736 401 RALRSLDLAGNQLTRLPEGLPASLRSLR---LQRNQLRTLEPEQLAGLNKLRELNLTHNRL 458
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKvldLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
398-553 |
7.66e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 58.02 E-value: 7.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 398 RRLRALRSLDLAGNQLTRLPEGLPASLRSLRLQRNqlrtlepEQLAGLNKLRELNLTHNRLRvgDIgPGTWHELQALKVL 477
Cdd:COG4886 72 LLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLT--DL-PEELANLTNLKEL 141
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 39645736 478 DLSHNELSFVPPDLPE--ALEELHLQANRISHVgPEAFLSTPHLRALFLRANRLhmtSIAAEALQGLTHLRVVDTAEN 553
Cdd:COG4886 142 DLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQI---TDLPEPLGNLTNLEELDLSGN 215
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
326-507 |
2.36e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 54.79 E-value: 2.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 326 LRPLRALHTLHLYGNKLERVPpalprhlqalvmphnhvaalgarDLVSARALAELNLAYNSLASARVhpsaFRRLRALRS 405
Cdd:cd21340 20 LSLCKNLKVLYLYDNKITKIE-----------------------NLEFLTNLTHLYLQNNQIEKIEN----LENLVNLKK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 406 LDLAGNQLTRLpEGL--PASLRSLRLQRNQLR-----TLEPEQLAGL-NKLRELNLTHNRLR-VGDIGPgtwheLQALKV 476
Cdd:cd21340 73 LYLGGNRISVV-EGLenLTNLEELHIENQRLPpgeklTFDPRSLAALsNSLRVLNISGNNIDsLEPLAP-----LRNLEQ 146
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 39645736 477 LDLSHNELSfvppDLPE---------ALEELHLQANRISH 507
Cdd:cd21340 147 LDASNNQIS----DLEElldllsswpSLRELDLTGNPVCK 182
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
342-565 |
3.91e-08 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 56.32 E-value: 3.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 342 LERVPPALPRHLQALVMPHNHVAALGA-----RDL-VSARALAELNLAYNSLASARVHPSAFRRLRALRS----LDLAGN 411
Cdd:PRK15387 213 LTTLPDCLPAHITTLVIPDNNLTSLPAlppelRTLeVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSglckLWIFGN 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 412 QLTRLPEgLPASLRSLRLQRNQLRTLE--PEQLAGL--------------NKLRELNLTHNRLRVGDIGPGTWHELQA-- 473
Cdd:PRK15387 293 QLTSLPV-LPPGLQELSVSDNQLASLPalPSELCKLwaynnqltslptlpSGLQELSVSDNQLASLPTLPSELYKLWAyn 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 474 ------------LKVLDLSHNELSFVPPdLPEALEELHLQANRISHVG--PEAFLSTPHLRALFLR--ANRLHMTSIAAE 537
Cdd:PRK15387 372 nrltslpalpsgLKELIVSGNRLTSLPV-LPSELKELMVSGNRLTSLPmlPSGLLSLSVYRNQLTRlpESLIHLSSETTV 450
|
250 260 270
....*....|....*....|....*....|....*
gi 39645736 538 ALQG-------LTHLRVVDTAENPEQVLVQLPRKG 565
Cdd:PRK15387 451 NLEGnplsertLQALREITSAPGYSGPIIRFDMAG 485
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
67-318 |
2.98e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 52.36 E-value: 2.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 67 RAARHLSLQNNQLRELPYN------ELSRLSGLRTLDLHSNLITSEGLPD-EAFESLNQLENFYVAHNKLSVAP-QFLPR 138
Cdd:cd00116 51 PSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCGVlESLLRSSSLQELKLNNNGLGDRGlRLLAK 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 139 SLRvaDLaanevveifpltfgeKPALRSVYLHNNRLRNTglppntfhGSEAITTLsLSSNQlsylppslpaSLERLHLQN 218
Cdd:cd00116 131 GLK--DL---------------PPALEKLVLGRNRLEGA--------SCEALAKA-LRANR----------DLKELNLAN 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 219 NLISkvPRGALSL------QTHLRELYLQHNQLTDSG--LDATTFSKLSSLEYLDLSHNQL-----ATVPEGLPG---TL 282
Cdd:cd00116 175 NGIG--DAGIRALaeglkaNCNLEVLDLNNNGLTDEGasALAETLASLKSLEVLNLGDNNLtdagaAALASALLSpniSL 252
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 39645736 283 TILHLGRNCIRHVEAVRLHKA----RGLRYLLLQHNKLGA 318
Cdd:cd00116 253 LTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFGE 292
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
397-554 |
3.30e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 51.33 E-value: 3.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 397 FRRLRALRSLDLAGNQLTRLpEGLPA--SLRSLRLQRNQLRTLEPeqLAGLNKLRELNLTHNRLRV--GdigpgtWHELQ 472
Cdd:cd21340 20 LSLCKNLKVLYLYDNKITKI-ENLEFltNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVveG------LENLT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 473 ALKVLDLSHNELsfvPPDLP------------EALEELHLQANRISHVGPEAFLStpHLRALFLRANRLHMTSIAAEALQ 540
Cdd:cd21340 91 NLEELHIENQRL---PPGEKltfdprslaalsNSLRVLNISGNNIDSLEPLAPLR--NLEQLDASNNQISDLEELLDLLS 165
|
170
....*....|....
gi 39645736 541 GLTHLRVVDTAENP 554
Cdd:cd21340 166 SWPSLRELDLTGNP 179
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
71-226 |
6.03e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.55 E-value: 6.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 71 HLSLQNNQLRELPYneLSRLSGLRTLDLHSNLITS-EGLpdeafESLNQLENFYVAHNKLSVAPQFL--PRSLRvadlaa 147
Cdd:cd21340 50 HLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVvEGL-----ENLTNLEELHIENQRLPPGEKLTfdPRSLA------ 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 148 nevveifpltfGEKPALRSVYLHNNRLRNtglpPNTFHGSEAITTLSLSSNQLSYLPPSLPA-----SLERLHLQNNLIS 222
Cdd:cd21340 117 -----------ALSNSLRVLNISGNNIDS----LEPLAPLRNLEQLDASNNQISDLEELLDLlsswpSLRELDLTGNPVC 181
|
....
gi 39645736 223 KVPR 226
Cdd:cd21340 182 KKPK 185
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
233-316 |
1.13e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 233 THLRELYLQHNQLTDsgLDATTFSKLSSLEYLDLSHNqlatvpeglpgtltilhlgrnCIRHVEAVRLHKARGLRYLLLQ 312
Cdd:pfam13855 1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNN---------------------LLTTLSPGAFSGLPSLRYLDLS 57
|
....
gi 39645736 313 HNKL 316
Cdd:pfam13855 58 GNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
447-529 |
5.01e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 5.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 447 KLRELNLTHNRLRVgdIGPGTWHELQALKVLDLSHNelsfvppdlpealeelhlqanRISHVGPEAFLSTPHLRALFLRA 526
Cdd:pfam13855 2 NLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNN---------------------LLTTLSPGAFSGLPSLRYLDLSG 58
|
...
gi 39645736 527 NRL 529
Cdd:pfam13855 59 NRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
495-549 |
5.37e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 5.37e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 39645736 495 LEELHLQANRISHVGPEAFLSTPHLRALFLRANRLhmTSIAAEALQGLTHLRVVD 549
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLD 55
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
162-389 |
6.09e-06 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 49.02 E-value: 6.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 162 PALRSVYLHNNRLRNTGLPPNTFHGSE--AITTLSLSSNQ-----LSYLPPSL--PASLERLHLQNNLIS----KVPRGA 228
Cdd:COG5238 208 TTVTTLWLKRNPIGDEGAEILAEALKGnkSLTTLDLSNNQigdegVIALAEALknNTTVETLYLSGNQIGaegaIALAKA 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 229 LSLQTHLRELYLQHNQLTDSGldATTFSKLssleyldLSHNQlatvpeglpgTLTILHLGRNCIRHVEAVRLHKA----R 304
Cdd:COG5238 288 LQGNTTLTSLDLSVNRIGDEG--AIALAEG-------LQGNK----------TLHTLNLAYNGIGAQGAIALAKAlqenT 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 305 GLRYLLLQHNKL---GASALPKgTLRPLRALHTLHLYGNKL-ERVPPALPRHLQalvmpHNHVAALGARD-LVSARALAE 379
Cdd:COG5238 349 TLHSLDLSDNQIgdeGAIALAK-YLEGNTTLRELNLGKNNIgKQGAEALIDALQ-----TNRLHTLILDGnLIGAEAQQR 422
|
250
....*....|
gi 39645736 380 LNLAYNSLAS 389
Cdd:COG5238 423 LEQLLERIKS 432
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
292-484 |
7.92e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 48.12 E-value: 7.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 292 IRHVEAVRLHKARGLRYLLLqhNKLGASALPKgTLRPLRALHTLHLYGNKLERVPPALPRHLQALV-------------- 357
Cdd:cd00116 16 TELLPKLLCLQVLRLEGNTL--GEEAAKALAS-ALRPQPSLKELCLSLNETGRIPRGLQSLLQGLTkgcglqeldlsdna 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 358 ----------------------MPHNHVAALGARDLVSA-----RALAELNLAYNSL--ASARVHPSAFRRLRALRSLDL 408
Cdd:cd00116 93 lgpdgcgvlesllrssslqelkLNNNGLGDRGLRLLAKGlkdlpPALEKLVLGRNRLegASCEALAKALRANRDLKELNL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 409 AGNQL-----TRLPEGLPAS--LRSLRLQRNQLRTLEPEQLAG----LNKLRELNLTHNRLR---VGDIGPGTWHELQAL 474
Cdd:cd00116 173 ANNGIgdagiRALAEGLKANcnLEVLDLNNNGLTDEGASALAEtlasLKSLEVLNLGDNNLTdagAAALASALLSPNISL 252
|
250
....*....|
gi 39645736 475 KVLDLSHNEL 484
Cdd:cd00116 253 LTLSLSCNDI 262
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
427-523 |
9.39e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 48.66 E-value: 9.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 427 LRLQRNQLRTLEPEQLAGLNKLRELNLTHNRLRvGDIgPGTWHELQALKVLDLSHNELS-FVPPDLPE--ALEELHLQAN 503
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIR-GNI-PPSLGSITSLEVLDLSYNSFNgSIPESLGQltSLRILNLNGN 500
|
90 100
....*....|....*....|
gi 39645736 504 RISHVGPEAFLSTPHLRALF 523
Cdd:PLN03150 501 SLSGRVPAALGGRLLHRASF 520
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
70-129 |
4.70e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 4.70e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 70 RHLSLQNNQLRELPYNELSRLSGLRTLDLHSNLITSegLPDEAFESLNQLENFYVAHNKL 129
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
87-320 |
6.34e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 45.55 E-value: 6.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 87 LSRLSGLRTLDLHSNLITSEGLPD--EAFESLNQLENFYVAHNKLSVapqflPRSLRVADLAANEvveifpltfgekPAL 164
Cdd:COG5238 232 LKGNKSLTTLDLSNNQIGDEGVIAlaEALKNNTTVETLYLSGNQIGA-----EGAIALAKALQGN------------TTL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 165 RSVYLHNNRLRNTGLPP--NTFHGSEAITTLSLSSNQLSylppslpaslerlhlqnnliskvPRGALSLQTHLRE----- 237
Cdd:COG5238 295 TSLDLSVNRIGDEGAIAlaEGLQGNKTLHTLNLAYNGIG-----------------------AQGAIALAKALQEnttlh 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 238 -LYLQHNQLTDSGLDAttfsklssleyldlshnqLATVPEGLPgTLTILHLGRNCIRHVEAVRLHKA---RGLRYLLLQH 313
Cdd:COG5238 352 sLDLSDNQIGDEGAIA------------------LAKYLEGNT-TLRELNLGKNNIGKQGAEALIDAlqtNRLHTLILDG 412
|
....*..
gi 39645736 314 NKLGASA 320
Cdd:COG5238 413 NLIGAEA 419
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
162-245 |
6.50e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.97 E-value: 6.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 162 PALRSVYLHNNRLrnTGLPPNTFHGSEAITTLSLSSNQLSYLPPslpaslerlhlqnnliskvprGALSLQTHLRELYLQ 241
Cdd:pfam13855 1 PNLRSLDLSNNRL--TSLDDGAFKGLSNLKVLDLSNNLLTTLSP---------------------GAFSGLPSLRYLDLS 57
|
....
gi 39645736 242 HNQL 245
Cdd:pfam13855 58 GNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
351-413 |
1.37e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.82 E-value: 1.37e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 39645736 351 RHLQALVMPHNHVAALGARDLVSARALAELNLAYNSLASarVHPSAFRRLRALRSLDLAGNQL 413
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
138-200 |
1.40e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.82 E-value: 1.40e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 39645736 138 RSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLrnTGLPPNTFHGSEAITTLSLSSNQL 200
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
395-530 |
8.53e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 42.08 E-value: 8.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 395 SAFRRLRALRSLDLAGNQLTrlPEGLPASLRSLRLQRnQLRTLE--------------PEQLAGLNKLRELNLTHNRLR- 459
Cdd:COG5238 230 EALKGNKSLTTLDLSNNQIG--DEGVIALAEALKNNT-TVETLYlsgnqigaegaialAKALQGNTTLTSLDLSVNRIGd 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 460 --VGDIGPGTWHElQALKVLDLSHNELSFVPPD-LPEALEE------LHLQANRISHVGPEAFL----STPHLRALFLRA 526
Cdd:COG5238 307 egAIALAEGLQGN-KTLHTLNLAYNGIGAQGAIaLAKALQEnttlhsLDLSDNQIGDEGAIALAkyleGNTTLRELNLGK 385
|
....
gi 39645736 527 NRLH 530
Cdd:COG5238 386 NNIG 389
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
394-458 |
1.68e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 41.34 E-value: 1.68e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 39645736 394 PSAFRRLRALRSLDLAGNQLT-RLPE--GLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLTHNRL 458
Cdd:PLN03150 435 PNDISKLRHLQSINLSGNSIRgNIPPslGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
233-273 |
2.09e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 36.07 E-value: 2.09e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 39645736 233 THLRELYLQHNQLTDSGLdattFSKLSSLEYLDLSHNQLAT 273
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPP----LAKLPNLETLDLSGNNKIT 37
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
91-174 |
4.30e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.96 E-value: 4.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 91 SGLRTLDLHSNLITSegLPDEAFESLNQLENFYVAHNKLSVapqflprslrvadlaanevveIFPLTFGEKPALRSVYLH 170
Cdd:pfam13855 1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTT---------------------LSPGAFSGLPSLRYLDLS 57
|
....
gi 39645736 171 NNRL 174
Cdd:pfam13855 58 GNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
379-553 |
8.29e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 38.76 E-value: 8.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 379 ELNLAYNSLASARVHPSAFRRLRALRSLDLAGNQLTRLPEGLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLTHNRL 458
Cdd:COG4886 3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645736 459 RVGDIGPGTWHELQALKVLDLSHNELSFVPPDlpeaLEELHLQANRISHVgPEAFLSTPHLRALFLRANRLhmTSIaAEA 538
Cdd:COG4886 83 SLLLLGLTDLGDLTNLTELDLSGNEELSNLTN----LESLDLSGNQLTDL-PEELANLTNLKELDLSNNQL--TDL-PEP 154
|
170
....*....|....*
gi 39645736 539 LQGLTHLRVVDTAEN 553
Cdd:COG4886 155 LGNLTNLKSLDLSNN 169
|
|
| |
