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Transmembrane and coiled-coil domains 3 [Mus musculus]
Protein Classification
cation:proton antiporter ( domain architecture ID 11111152 )
cation:proton antiporter functions in maintaining cation homeostasis and the pH of actively metabolizing cells; it may also be involved in regulating cell volume; similar to K(+) efflux antiporters that are involved in K(+) homeostasis and osmotic adjustment
List of domain hits
Name
Accession
Description
Interval
E-value
RosB super family
cl47355 Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
267-646
1.72e-61
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];
COG4651 :Pssm-ID: 443689 [Multi-domain]
Cd Length: 564
Bit Score: 215.22
E-value: 1.72e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 267 DHHF I KD I VT I GM L SLPC G W L CTAIGL P TMF GY IIC GVL L GP SGLNSIKSIVQV E T L G E F GV FFT LF L VGLEFS PEK L RK 346
Cdd:COG4651 3 ETPL I TT I AL I LG L AAVL G L L AQRLRQ P PIV GY LLA GVL I GP FTPGLVADVELI E Q L A E I GV ILL LF G VGLEFS LKD L LA 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 347 V WR I S L Q G PCYMTL L MIAF G LWWGH LL RIRPTQ S VFISTC LSLSST PLVSRF L VGSARG D KEA G D I D ystvl L G M L VM QD 426
Cdd:COG4651 83 V RK I A L P G ALLQIA L TTLL G FGIAL LL GWSLGE S LVFGLA LSLSST VVLLKL L EDRGEL D TLH G R I A ----- V G W L IV QD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 427 VQLG L FIAVM P T L iqag AG ASSSVVME vlrilfl I G QI L FSL A AVFL L C LV MKTYL I GPYYRKL hl ESKGNK E ILV L G V S 506
Cdd:COG4651 158 LAVV L MLVLL P A L ---- AG GGGGLLGT ------- L G LT L LKV A LFVA L M LV VGRRV I PWLLHRV -- ARTRSR E LFL L A V L 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 507 A FTFLMLTVTE L LDV S ME LG C FLAG ALVSS -- QG H MVTE E IM tyie P I RD FL A II FF A S I G LHVF P T F VIYELTVLVF L T 584
Cdd:COG4651 225 A ICLGVAYLAA L FGL S FA LG A FLAG MVLAE se YS H QAAA E LL ---- P L RD AF A VL FF V S V G MLFD P S F LLENPLPVLA L L 300
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25058558 585 L S V V I M K FVL A V L VLSLI lp RSSQYIKWI V SAG LAQ VS EFSF V L GSRARRA G I LS R E V Y L LI 646
Cdd:COG4651 301 L I V L I G K PLI A F L IVLAL -- GYPLRTALL V GLS LAQ IG EFSF I L AALGLSL G L LS E E A Y Q LI 360
Name
Accession
Description
Interval
E-value
RosB
COG4651 Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
267-646
1.72e-61
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];
Pssm-ID: 443689 [Multi-domain]
Cd Length: 564
Bit Score: 215.22
E-value: 1.72e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 267 DHHF I KD I VT I GM L SLPC G W L CTAIGL P TMF GY IIC GVL L GP SGLNSIKSIVQV E T L G E F GV FFT LF L VGLEFS PEK L RK 346
Cdd:COG4651 3 ETPL I TT I AL I LG L AAVL G L L AQRLRQ P PIV GY LLA GVL I GP FTPGLVADVELI E Q L A E I GV ILL LF G VGLEFS LKD L LA 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 347 V WR I S L Q G PCYMTL L MIAF G LWWGH LL RIRPTQ S VFISTC LSLSST PLVSRF L VGSARG D KEA G D I D ystvl L G M L VM QD 426
Cdd:COG4651 83 V RK I A L P G ALLQIA L TTLL G FGIAL LL GWSLGE S LVFGLA LSLSST VVLLKL L EDRGEL D TLH G R I A ----- V G W L IV QD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 427 VQLG L FIAVM P T L iqag AG ASSSVVME vlrilfl I G QI L FSL A AVFL L C LV MKTYL I GPYYRKL hl ESKGNK E ILV L G V S 506
Cdd:COG4651 158 LAVV L MLVLL P A L ---- AG GGGGLLGT ------- L G LT L LKV A LFVA L M LV VGRRV I PWLLHRV -- ARTRSR E LFL L A V L 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 507 A FTFLMLTVTE L LDV S ME LG C FLAG ALVSS -- QG H MVTE E IM tyie P I RD FL A II FF A S I G LHVF P T F VIYELTVLVF L T 584
Cdd:COG4651 225 A ICLGVAYLAA L FGL S FA LG A FLAG MVLAE se YS H QAAA E LL ---- P L RD AF A VL FF V S V G MLFD P S F LLENPLPVLA L L 300
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25058558 585 L S V V I M K FVL A V L VLSLI lp RSSQYIKWI V SAG LAQ VS EFSF V L GSRARRA G I LS R E V Y L LI 646
Cdd:COG4651 301 L I V L I G K PLI A F L IVLAL -- GYPLRTALL V GLS LAQ IG EFSF I L AALGLSL G L LS E E A Y Q LI 360
Na_H_Exchanger
pfam00999 Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
274-646
4.17e-55
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain]
Cd Length: 377
Bit Score: 192.86
E-value: 4.17e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 274 IV TIGM L S L PCGW L CTAIG LP TMF G Y II C G V LLGPSGL NS I KSI - VQV E T L GEF G VFFT LFL V GLE FSPEK LRK VWRIS L 352
Cdd:pfam00999 1 IV LLIL L A L LAPL L ARRLK LP PIV G L II A G I LLGPSGL GL I SEV d EDL E V L SNL G LPPL LFL A GLE LDLRE LRK NGGSI L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 353 QGPCYMT L LM --- I AFG L WWG h L L R I RPTQSVFISTC LS LS S TPL V SRF L VGSA R GDKEA G didys T V LLG ML V MQ D VQL 429
Cdd:pfam00999 81 LLALLGV L IP fvl I GLL L YLL - G L G I PLLEALLFGAI LS AT S PVV V LAI L KELG R VPERL G ----- T L LLG ES V LN D GVA 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 430 GLFI AV MPT L I Q AGA G A S S svvmevlri L FLIGQ I LFSL A AVF LL CLV mkty LIG PYY R KLHLESKGNK E IL VL G V SAFT 509
Cdd:pfam00999 155 VVLL AV LLA L A Q GVG G G S D --------- L GWLLL I FLVV A VGG LL LGL ---- LIG WLL R LITRFTDDDR E LE VL L V LLLA 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 510 F L MLTVT E L L D VS ME LG C FLAG ALV S sq GHMVTEEIMTYI EP IRDF L AI - I FF ASI GL HVFPTFVIYELTV LV F L T L SVV 588
Cdd:pfam00999 222 L L AALLA E A L G VS GI LG A FLAG LVL S -- EYPFANKLSEKL EP FGYG L FN p L FF VLV GL SLDLSSLLLSVWI LV L L A L VAI 299
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 25058558 589 IMKFV L A V LV L SLI L PR S SQY i KW I VSA G LA Q VSEF S FV L GSRARRA GI LS RE V Y L L I 646
Cdd:pfam00999 300 LLGRF L G V FL L LRL L GL S LRE - AL I IGF G GL Q RGAV S LA L AAIGPLL GI IA RE L Y P L L 356
2a37
TIGR00932 transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
284-568
3.37e-31
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273348 [Multi-domain]
Cd Length: 273
Bit Score: 123.14
E-value: 3.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 284 CGW L CTAI G L P TMF GY IIC GVL L GPSGL NS I KSIVQ V ET L G EFGV FFTL FL V GLE FSP E K L R K VWRISL - Q G PCYMTLLM 362
Cdd:TIGR00932 7 AVP L SRRL G I P SVL GY LLA GVL I GPSGL GL I SNVEG V NH L A EFGV ILLM FL I GLE LDL E R L W K LRKAAF g V G VLQVLVPG 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 363 IAF GL WW GHLL RIRPTQS V F I STC L S LSST PL V SRF L VGSARGDKEA G didys TVL LG M L VM QD vqlglf IAV M P T L IQA 442
Cdd:TIGR00932 87 VLL GL LL GHLL GLALGAA V V I GII L A LSST AV V VQV L KERGLLKTPF G ----- QTV LG I L LF QD ------ IAV V P L L ALL 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 443 GAG A S S SVVME V LRI L F L IGQI L FS L AA V F L L clvmk TY L IG P YY R KLH le SKGNK E ILVL G VSAFT F LMLTVTE LL DV S 522
Cdd:TIGR00932 156 PLL A T S ASTEH V ALA L L L LKVF L AF L LL V L L G ----- RW L LR P VL R LTA -- ELRPS E LFTA G SLLLM F GSAYFAD LL GL S 228
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 25058558 523 M E LG C FLAG ALV -- S SQG H MVTEE imty I EPI RDF L AII FF A S I G LH V 568
Cdd:TIGR00932 229 M A LG A FLAG VVL se S EYR H KLESD ---- L EPI GGV L LPL FF I S V G MS V 272
PRK03659
PRK03659 glutathione-regulated potassium-efflux system protein KefB; Provisional
292-641
3.34e-23
glutathione-regulated potassium-efflux system protein KefB; Provisional
Pssm-ID: 179625 [Multi-domain]
Cd Length: 601
Bit Score: 104.34
E-value: 3.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 292 G LPTMF GY IIC G VLL GP S GL NS I KSIVQVETLG E F GV F F TL F LV GLE FS P E KL rkv W R is L QGP ------------- CYM 358
Cdd:PRK03659 28 G IGAVL GY LLA G IAI GP W GL GF I SDVDEILHFS E L GV V F LM F II GLE LN P S KL --- W Q -- L RRS ifgvgaaqvllsa AVL 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 359 TL L MIAFGLW W ghllrirp TQS V FISTC L SL SST PLVSRFLVGSARGDK E A G DIDY S t VLL gmlv M QD vqlglf I AV M P T 438
Cdd:PRK03659 103 AG L LMLTDFS W -------- QAA V VGGIG L AM SST AMALQLMREKGMNRS E S G QLGF S - VLL ---- F QD ------ L AV I P A 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 439 L ---- IQ AG AGASSSVV M evlrilflig Q I LFSLA A VFLL c L VMKT YL IG P YY R kl HLESK G NK E I ------- LVLG VSA 507
Cdd:PRK03659 164 L alvp LL AG SADEHFDW M ---------- K I GMKVL A FAGM - L IGGR YL LR P LF R -- FIAAS G VR E V ftaaall LVLG SAL 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 508 F tflmltv TEL L DV SM E LG C F L AG A L V -- S SQG H mvte E IMTY IEP IRDF L AII FF A S I G LHV - FPTFVIYE L T VL VFLT 584
Cdd:PRK03659 231 F ------- MDA L GL SM A LG T F I AG V L L ae S EYR H ---- E LEIA IEP FKGL L LGL FF I S V G MAL n LGVLYTHL L W VL ISVV 299
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 25058558 585 LS V VIMKF VL AV L VLSLI L p RSS QYIKW iv SAG L A Q VS EF S FVL G S R A RRAGI L SRE 641
Cdd:PRK03659 300 VL V AVKGL VL YL L ARLYG L - RSS ERMQF -- AGV L S Q GG EF A FVL F S A A SSQRL L QGD 353
Name
Accession
Description
Interval
E-value
RosB
COG4651 Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
267-646
1.72e-61
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];
Pssm-ID: 443689 [Multi-domain]
Cd Length: 564
Bit Score: 215.22
E-value: 1.72e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 267 DHHF I KD I VT I GM L SLPC G W L CTAIGL P TMF GY IIC GVL L GP SGLNSIKSIVQV E T L G E F GV FFT LF L VGLEFS PEK L RK 346
Cdd:COG4651 3 ETPL I TT I AL I LG L AAVL G L L AQRLRQ P PIV GY LLA GVL I GP FTPGLVADVELI E Q L A E I GV ILL LF G VGLEFS LKD L LA 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 347 V WR I S L Q G PCYMTL L MIAF G LWWGH LL RIRPTQ S VFISTC LSLSST PLVSRF L VGSARG D KEA G D I D ystvl L G M L VM QD 426
Cdd:COG4651 83 V RK I A L P G ALLQIA L TTLL G FGIAL LL GWSLGE S LVFGLA LSLSST VVLLKL L EDRGEL D TLH G R I A ----- V G W L IV QD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 427 VQLG L FIAVM P T L iqag AG ASSSVVME vlrilfl I G QI L FSL A AVFL L C LV MKTYL I GPYYRKL hl ESKGNK E ILV L G V S 506
Cdd:COG4651 158 LAVV L MLVLL P A L ---- AG GGGGLLGT ------- L G LT L LKV A LFVA L M LV VGRRV I PWLLHRV -- ARTRSR E LFL L A V L 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 507 A FTFLMLTVTE L LDV S ME LG C FLAG ALVSS -- QG H MVTE E IM tyie P I RD FL A II FF A S I G LHVF P T F VIYELTVLVF L T 584
Cdd:COG4651 225 A ICLGVAYLAA L FGL S FA LG A FLAG MVLAE se YS H QAAA E LL ---- P L RD AF A VL FF V S V G MLFD P S F LLENPLPVLA L L 300
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25058558 585 L S V V I M K FVL A V L VLSLI lp RSSQYIKWI V SAG LAQ VS EFSF V L GSRARRA G I LS R E V Y L LI 646
Cdd:COG4651 301 L I V L I G K PLI A F L IVLAL -- GYPLRTALL V GLS LAQ IG EFSF I L AALGLSL G L LS E E A Y Q LI 360
KefB
COG0475 Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
268-646
8.23e-57
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 197.68
E-value: 8.23e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 268 HHFIKDIVTIGMLSLPC G W L CTAI GLP TMF GYI IC G V LLGPSGL NS I KSIVQV E T L G E F GV FFT LFL V GLE FSPEK LRK V 347
Cdd:COG0475 3 ASLLLQLGLLLLAAVLA G L L ARRL GLP SVL GYI LA G I LLGPSGL GL I EDSEAL E L L A E L GV VLL LFL I GLE LDLKR LRK M 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 348 W R IS L QGPCYMT LL MIAF G LWWGH LL RIRPTQSV F ISTC L SLS ST PL V SRF L vgsargd KE A G DID -- YSTVL LG MLVMQ 425
Cdd:COG0475 83 G R RA L GIGLLQV LL PFLL G FLLAL LL GLSLAAAL F LGAA L AAT ST AI V LKV L ------- KE L G LLK tp LGQLI LG VALFD 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 426 D VQLG L FI A VM P T L IQA G AG A S S svvmevlr I L FLIGQI L FS LA AVF L LCL vmkt YL IGPYY R kl HLESKGNK E ILV L GV 505
Cdd:COG0475 156 D IAAI L LL A LV P A L AGG G SV A G S -------- L L LALLKA L LF LA LLL L VGR ---- YL LRRLF R -- LVARTRSR E LFL L FA 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 506 SAFTF L MLTVT ELL DV S ME LG C FLAG ALVSSQGH mv TE E IMTY IEP IR D FLAII FF A S I GL HVFPTFVIYELTVLVF L T L 585
Cdd:COG0475 222 LLLVL L AAALA ELL GL S AA LG A FLAG LVLAESEY -- RH E LEEK IEP FG D LFLPL FF V S V GL SLDLSALLSNPLLALL L V L 299
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25058558 586 SVVIM K FVL A V L VLS L I lp RS S QYIKWIVSAG LA QVS EF SF VL G S RARR AG IL S R E VYLLI 646
Cdd:COG0475 300 AAIVG K LLG A Y L AAR L F -- GL S RREALRIGLL LA PRG EF AL VL A S LGLS AG LI S P E LFAAL 358
Na_H_Exchanger
pfam00999 Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
274-646
4.17e-55
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain]
Cd Length: 377
Bit Score: 192.86
E-value: 4.17e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 274 IV TIGM L S L PCGW L CTAIG LP TMF G Y II C G V LLGPSGL NS I KSI - VQV E T L GEF G VFFT LFL V GLE FSPEK LRK VWRIS L 352
Cdd:pfam00999 1 IV LLIL L A L LAPL L ARRLK LP PIV G L II A G I LLGPSGL GL I SEV d EDL E V L SNL G LPPL LFL A GLE LDLRE LRK NGGSI L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 353 QGPCYMT L LM --- I AFG L WWG h L L R I RPTQSVFISTC LS LS S TPL V SRF L VGSA R GDKEA G didys T V LLG ML V MQ D VQL 429
Cdd:pfam00999 81 LLALLGV L IP fvl I GLL L YLL - G L G I PLLEALLFGAI LS AT S PVV V LAI L KELG R VPERL G ----- T L LLG ES V LN D GVA 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 430 GLFI AV MPT L I Q AGA G A S S svvmevlri L FLIGQ I LFSL A AVF LL CLV mkty LIG PYY R KLHLESKGNK E IL VL G V SAFT 509
Cdd:pfam00999 155 VVLL AV LLA L A Q GVG G G S D --------- L GWLLL I FLVV A VGG LL LGL ---- LIG WLL R LITRFTDDDR E LE VL L V LLLA 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 510 F L MLTVT E L L D VS ME LG C FLAG ALV S sq GHMVTEEIMTYI EP IRDF L AI - I FF ASI GL HVFPTFVIYELTV LV F L T L SVV 588
Cdd:pfam00999 222 L L AALLA E A L G VS GI LG A FLAG LVL S -- EYPFANKLSEKL EP FGYG L FN p L FF VLV GL SLDLSSLLLSVWI LV L L A L VAI 299
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 25058558 589 IMKFV L A V LV L SLI L PR S SQY i KW I VSA G LA Q VSEF S FV L GSRARRA GI LS RE V Y L L I 646
Cdd:pfam00999 300 LLGRF L G V FL L LRL L GL S LRE - AL I IGF G GL Q RGAV S LA L AAIGPLL GI IA RE L Y P L L 356
2a37
TIGR00932 transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
284-568
3.37e-31
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273348 [Multi-domain]
Cd Length: 273
Bit Score: 123.14
E-value: 3.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 284 CGW L CTAI G L P TMF GY IIC GVL L GPSGL NS I KSIVQ V ET L G EFGV FFTL FL V GLE FSP E K L R K VWRISL - Q G PCYMTLLM 362
Cdd:TIGR00932 7 AVP L SRRL G I P SVL GY LLA GVL I GPSGL GL I SNVEG V NH L A EFGV ILLM FL I GLE LDL E R L W K LRKAAF g V G VLQVLVPG 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 363 IAF GL WW GHLL RIRPTQS V F I STC L S LSST PL V SRF L VGSARGDKEA G didys TVL LG M L VM QD vqlglf IAV M P T L IQA 442
Cdd:TIGR00932 87 VLL GL LL GHLL GLALGAA V V I GII L A LSST AV V VQV L KERGLLKTPF G ----- QTV LG I L LF QD ------ IAV V P L L ALL 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 443 GAG A S S SVVME V LRI L F L IGQI L FS L AA V F L L clvmk TY L IG P YY R KLH le SKGNK E ILVL G VSAFT F LMLTVTE LL DV S 522
Cdd:TIGR00932 156 PLL A T S ASTEH V ALA L L L LKVF L AF L LL V L L G ----- RW L LR P VL R LTA -- ELRPS E LFTA G SLLLM F GSAYFAD LL GL S 228
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 25058558 523 M E LG C FLAG ALV -- S SQG H MVTEE imty I EPI RDF L AII FF A S I G LH V 568
Cdd:TIGR00932 229 M A LG A FLAG VVL se S EYR H KLESD ---- L EPI GGV L LPL FF I S V G MS V 272
PRK03659
PRK03659 glutathione-regulated potassium-efflux system protein KefB; Provisional
292-641
3.34e-23
glutathione-regulated potassium-efflux system protein KefB; Provisional
Pssm-ID: 179625 [Multi-domain]
Cd Length: 601
Bit Score: 104.34
E-value: 3.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 292 G LPTMF GY IIC G VLL GP S GL NS I KSIVQVETLG E F GV F F TL F LV GLE FS P E KL rkv W R is L QGP ------------- CYM 358
Cdd:PRK03659 28 G IGAVL GY LLA G IAI GP W GL GF I SDVDEILHFS E L GV V F LM F II GLE LN P S KL --- W Q -- L RRS ifgvgaaqvllsa AVL 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 359 TL L MIAFGLW W ghllrirp TQS V FISTC L SL SST PLVSRFLVGSARGDK E A G DIDY S t VLL gmlv M QD vqlglf I AV M P T 438
Cdd:PRK03659 103 AG L LMLTDFS W -------- QAA V VGGIG L AM SST AMALQLMREKGMNRS E S G QLGF S - VLL ---- F QD ------ L AV I P A 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 439 L ---- IQ AG AGASSSVV M evlrilflig Q I LFSLA A VFLL c L VMKT YL IG P YY R kl HLESK G NK E I ------- LVLG VSA 507
Cdd:PRK03659 164 L alvp LL AG SADEHFDW M ---------- K I GMKVL A FAGM - L IGGR YL LR P LF R -- FIAAS G VR E V ftaaall LVLG SAL 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 508 F tflmltv TEL L DV SM E LG C F L AG A L V -- S SQG H mvte E IMTY IEP IRDF L AII FF A S I G LHV - FPTFVIYE L T VL VFLT 584
Cdd:PRK03659 231 F ------- MDA L GL SM A LG T F I AG V L L ae S EYR H ---- E LEIA IEP FKGL L LGL FF I S V G MAL n LGVLYTHL L W VL ISVV 299
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 25058558 585 LS V VIMKF VL AV L VLSLI L p RSS QYIKW iv SAG L A Q VS EF S FVL G S R A RRAGI L SRE 641
Cdd:PRK03659 300 VL V AVKGL VL YL L ARLYG L - RSS ERMQF -- AGV L S Q GG EF A FVL F S A A SSQRL L QGD 353
PRK03562
PRK03562 glutathione-regulated potassium-efflux system protein KefC; Provisional
290-641
2.70e-20
glutathione-regulated potassium-efflux system protein KefC; Provisional
Pssm-ID: 235131 [Multi-domain]
Cd Length: 621
Bit Score: 95.45
E-value: 2.70e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 290 AI GL PTMF GY I I C G VLL GP S GL NSIKSIVQVETLG EFGV FFT LF LV GLE FS P EK L R K VW R I ----- S LQ - GP C -- YMT L L 361
Cdd:PRK03562 26 RL GL GSVL GY L I A G CII GP W GL RLVTDVESILHFA EFGV VLM LF VI GLE LD P QR L W K LR R S ifggg A LQ m VA C gg LLG L F 105
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 362 MIAF GL W W ghllrirp TQSVF I STC L S LSST P ----- LVS R F L VGSAR G DKE agdidystvl LGM L VM QD VQLGLFI A VM 436
Cdd:PRK03562 106 CMLL GL R W -------- QVALL I GLG L A LSST A iamqa MNE R N L MVTQM G RSA ---------- FAI L LF QD IAAIPLV A MI 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 437 P T L - IQAGAGASSSVVMEV L RILFLI gqilfsl A A V F L L clvm KT Y LIG P YY R kl HLESK G NK E IL ---- VLG V SA F TF L 511
Cdd:PRK03562 168 P L L a ASGASTTLGAFALSA L KVAGAL ------- A L V V L G ---- GR Y VTR P AL R -- FVARS G LR E VF tava LFL V FG F GL L 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 512 M ltvt E LLDV SM E LG C FLAG A L VS S QGH mv TEEIMTY IEP IRDF L AII FF ASI G LHV - F P T FVIYE L TV L VF L TLSVV I M 590
Cdd:PRK03562 235 M ---- E EVGL SM A LG A FLAG V L LA S SEY -- RHALESD IEP FKGL L LGL FF IAV G MSI d F G T LLENP L RI L IL L LGFLA I K 308
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 25058558 591 KFV L AV L VLS L IL PR SSQ yik WIVSAG L A Q VS EF S FV LGSR A RR A GI L SR E 641
Cdd:PRK03562 309 IAM L WL L ARP L GV PR KQR --- RWFAVL L G Q GG EF A FV VFGA A QM A NV L EP E 356
PRK10669
PRK10669 putative cation:proton antiport protein; Provisional
268-641
1.95e-17
putative cation:proton antiport protein; Provisional
Pssm-ID: 182633 [Multi-domain]
Cd Length: 558
Bit Score: 85.92
E-value: 1.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 268 HH FIKD I V TI GM --- L SLPC G W L CTAIGLPTMF GY IIC GVL L GP SGLNSIKSIVQVET L G E F GV FFTL F L VGL E FS PEK L 344
Cdd:PRK10669 2 HH ATPL I T TI VG glv L AFIL G M L ANRLRISPLV GY LLA GVL A GP FTPGFVADTKLAPE L A E L GV ILLM F G VGL H FS LKD L 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 345 RK V WR I SLQ G PCYMTLLMIAF G LWWGHL L RIRPTQSVFIST CLS LS ST ----- P L VS R F L VG S A RG D keagdidyst VLL 419
Cdd:PRK10669 82 MA V KS I AIP G AIAQIAVATLL G MALSAV L GWSLMTGIVFGL CLS TA ST vvllr A L EE R Q L ID S Q RG Q ---------- IAI 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 420 G M L VMQ D VQLG L FIAVM P TLIQAGAGASSSVVMEVLRILFL IG QIL fsla A VFLLCLVMKTY L IGPYYRKL hl ESK G NK E 499
Cdd:PRK10669 152 G W L IVE D LVMV L TLVLL P AVAGMMEQGDVGFATLAVDLGIT IG KVI ---- A FIAIMMLVGRR L VPWILARS -- AAT G SR E 225
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 500 ILV L G V S A FTF - LMLTVT EL L DVS ME LG C F L AG ALV -- S SQG H MVTEEIM tyie P I RD FL A II FF A S I G L h V F PTFVIYE 576
Cdd:PRK10669 226 LFT L S V L A LAL g IAFGAV EL F DVS FA LG A F F AG MVL ne S ELS H RAAHDTL ---- P L RD AF A VL FF V S V G M - L F DPMILIQ 300
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25058558 577 LTVL V FL TL SVVIMKFV LA VLV L SLILPR S SQ y IKWIVS A G LAQ VS EF S F V L GSRARRAGI L SRE 641
Cdd:PRK10669 301 QPLA V LA TL AIIVFGKS LA AFF L VRLFGH S RR - TALTIA A S LAQ IG EF A F I L AGLGMALNL L PQA 364
NhaP
COG0025 NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
274-617
2.52e-05
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 439796 [Multi-domain]
Cd Length: 506
Bit Score: 47.27
E-value: 2.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 274 I VTIGM L S L PCG WL CTAIG LP TMFGYIIC G V LLGP s GL NSI -- KSIVQV E T L G E FGVFFT LF LVG L EFSPEK LR KVW R IS 351
Cdd:COG0025 7 I LLLLL L G L LSQ WL ARRLK LP APLLLLLA G I LLGP - GL GLE ld PELGDL E P L L E LFLPPL LF EAA L NLDLRE LR RNG R PI 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 352 L Q --- GPCYM T L L MI A FGLW W gh LL RIRPTQSVFISTC L S ---------- L SSTPL --- VSRF L V G sargdk E AGDI D YS 415
Cdd:COG0025 86 L R lav VGVLL T T L AV A LAAH W -- LL GLPLAAALLLGAI L A ptdpvavspi L RRLGV pkr LRTI L E G ------ E SLLN D AT 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 416 TVL L GM L VMQ dvqlglfiavmpt LIQA G AGASSSVVMEV L ri L FLI G Q IL FS L AAVF LL CLVMK tyligpyyrkl H L ESK 495
Cdd:COG0025 158 ALV L FV L ALA ------------- AALG G GFSLGEALLDF L -- L AIL G G IL VG L LLGW LL GRLLR ----------- R L PDP 211
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 496 GNKEI L V L GVSAFTF L mlt VT E L L DV S ME L GCFL AG ALVSSQ G HMVT ----- EEIMTYI E PIRDF L AIIF F ASI G LHV - F 569
Cdd:COG0025 212 LLEIL L T L ALPFLAY L --- LA E A L HG S GV L AVVV AG LVLGNA G RRSL spetr LQLLEFW E TLEFL L NSLL F VLL G AQL p L 288
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 25058558 570 PTFVIYE L TVLVFLT L SVVIMKFVLAV L V L S L ILP R S S QYIKWIV S A G 617
Cdd:COG0025 289 ILLGALG L GGILLVL L ALLVVRPLWVF L S L A L RGS R L S WRERLFL S W G 336
PLN03159
PLN03159 cation/H(+) antiporter 15; Provisional
294-566
5.69e-04
cation/H(+) antiporter 15; Provisional
Pssm-ID: 215608 [Multi-domain]
Cd Length: 832
Bit Score: 43.34
E-value: 5.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 294 P TMFGY I IC GV L LGPS G L NSIK ---------- S IVQV ET LGEF G VFFT LFLVG L E FSPEKL R KVWR ---- I SLQ G PCYMT 359
Cdd:PLN03159 68 P RVISE I LG GV I LGPS V L GQSE vfantifplr S VMVL ET MANL G LLYF LFLVG V E MDISVI R RTGK kala I AIA G MALPF 147
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 360 LLMI AF GLWWGHLL R I -- RP T QSV F ISTC LS LSST P LVS R F L VGSARGDK E A G D I DY S TV L L gmlvm Q D VQLGLFI A VMP 437
Cdd:PLN03159 148 CIGL AF SFIFHQVS R N vh QG T FIL F LGVA LS VTAF P VLA R I L AEIKLINT E L G R I AM S AA L V ----- N D MCAWILL A LAI 222
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25058558 438 T L IQAGAGASS S vvmevlr ILF L IGQIL F S L AAVFLLCLVM k TYL I gpy Y R KLHL E SKGNKE I - L V L gvsaf T FL M LT -- 514
Cdd:PLN03159 223 A L AENDSTSLA S ------- LWV L LSSVA F V L FCFYVVRPGI - WWI I --- R R TPEG E TFSEFY I c L I L ----- T GV M IS gf 286
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 25058558 515 V T ELLDVSMEL G C F LA G a LV SSQ G HMV teei M T Y IE PIR DF ---- L AII FFA SI GL 566
Cdd:PLN03159 287 I T DAIGTHSVF G A F VF G - LV IPN G PLG ---- V T L IE KLE DF vsgl L LPL FFA IS GL 337
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
