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Conserved domains on  [gi|15079243|gb|AAH11454|]
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AMOTL2 protein [Homo sapiens]

Protein Classification

Smc and Angiomotin_C domain-containing protein( domain architecture ID 10573751)

Smc and Angiomotin_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Angiomotin_C pfam12240
Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 ...
169-374 1.05e-92

Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.


:

Pssm-ID: 463503 [Multi-domain]  Cd Length: 200  Bit Score: 279.34  E-value: 1.05e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   169 YVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGsggspELSALRLSEQLREKEEQILA 248
Cdd:pfam12240   1 YVEKVERLQQALAQLQAACEKREQLELRLRTRLEQELKSLRAQQRQGGSQGSGPS-----EYSAPALMELLREKEERILA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   249 LEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDA 328
Cdd:pfam12240  76 LEADMTKWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRHSYDSSFNEELLLANRRCQEMENRIKNLHAQILEKDA 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 15079243   329 VIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFaAAAAGTQGWQGLSS 374
Cdd:pfam12240 156 MIKVLQQRSRKDPGKTDQQSLRPARSVPSIS-AAATGLHSRQTSLS 200
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
2-268 1.68e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.68e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   2 EAVLRENARLQRDNERLQRELES-SAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKtmrnkmdsEMRRLQDFNRD 80
Cdd:COG1196 242 EELEAELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--------DIARLEERRRE 313
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  81 LRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAE 160
Cdd:COG1196 314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 161 EELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLR 240
Cdd:COG1196 394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
                       250       260
                ....*....|....*....|....*...
gi 15079243 241 EKEEQILALEADMTKWEQKYLEERAMRQ 268
Cdd:COG1196 474 LLEAALAELLEELAEAAARLLLLLEAEA 501
 
Name Accession Description Interval E-value
Angiomotin_C pfam12240
Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 ...
169-374 1.05e-92

Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.


Pssm-ID: 463503 [Multi-domain]  Cd Length: 200  Bit Score: 279.34  E-value: 1.05e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   169 YVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGsggspELSALRLSEQLREKEEQILA 248
Cdd:pfam12240   1 YVEKVERLQQALAQLQAACEKREQLELRLRTRLEQELKSLRAQQRQGGSQGSGPS-----EYSAPALMELLREKEERILA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   249 LEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDA 328
Cdd:pfam12240  76 LEADMTKWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRHSYDSSFNEELLLANRRCQEMENRIKNLHAQILEKDA 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 15079243   329 VIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFaAAAAGTQGWQGLSS 374
Cdd:pfam12240 156 MIKVLQQRSRKDPGKTDQQSLRPARSVPSIS-AAATGLHSRQTSLS 200
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
2-268 1.68e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.68e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   2 EAVLRENARLQRDNERLQRELES-SAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKtmrnkmdsEMRRLQDFNRD 80
Cdd:COG1196 242 EELEAELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--------DIARLEERRRE 313
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  81 LRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAE 160
Cdd:COG1196 314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 161 EELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLR 240
Cdd:COG1196 394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
                       250       260
                ....*....|....*....|....*...
gi 15079243 241 EKEEQILALEADMTKWEQKYLEERAMRQ 268
Cdd:COG1196 474 LLEAALAELLEELAEAAARLLLLLEAEA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
31-391 2.52e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.52e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  31 RIEKLESEIQRLSEAHESLTRassKREALEKTMRnKMDSEMRRLQDFNRDLRERLESANRRLASKTQEaqagsqdmVAKL 110
Cdd:COG1196 233 KLRELEAELEELEAELEELEA---ELEELEAELA-ELEAELEELRLELEELELELEEAQAEEYELLAE--------LARL 300
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 111 LAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQayvekvERLQQALGQLQAACEKR 190
Cdd:COG1196 301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAEAEL 374
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 191 EQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFA 270
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 271 MDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLtgghRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLR 350
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELA----EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
                       330       340       350       360
                ....*....|....*....|....*....|....*....|.
gi 15079243 351 PAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPARLTTDRA 391
Cdd:COG1196 531 GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA 571
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
2-265 1.18e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243      2 EAVLRENARLQRDNERLQRELESSAEK----AGRIEKLESEIQRLSEAHESLTRASSK-REALEKTMRN-------KMDS 69
Cdd:TIGR02169  719 GEIEKEIEQLEQEEEKLKERLEELEEDlsslEQEIENVKSELKELEARIEELEEDLHKlEEALNDLEARlshsripEIQA 798
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     70 EMRRLQDFNRDLRERLESANRRLASKTQEAQAgSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQAL 149
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEY-LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    150 GNAQGRAARAEEELRKKQAyveKVERLQQALGQLQAACEKREQLELRLRTRLEqelkALRAQQRQAGAPGGSSGSGGSPE 229
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEA---QLRELERKIEELEAQIEKKRKRLSELKAKLE----ALEEELSEIEDPKGEDEEIPEEE 950
                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 15079243    230 LSALRLSEQLREKEEQILALEADMTKWEQKYLEERA 265
Cdd:TIGR02169  951 LSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLK 986
PTZ00121 PTZ00121
MAEBL; Provisional
2-263 1.51e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     2 EAVLRENARLQRDNERLQRELESSAEKAGRIEKLEseiQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDL 81
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK---KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    82 RERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLE-----QALGNAQGRA 156
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEvmklyEEEKKMKAEE 1611
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   157 ARAEEELRKKQAYVEKVERLQQALGQLQA--ACEKREQLELR-----LRTRLEQELKALRAQQRQAGAPGGSSGSGGSPE 229
Cdd:PTZ00121 1612 AKKAEEAKIKAEELKKAEEEKKKVEQLKKkeAEEKKKAEELKkaeeeNKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691
                         250       260       270
                  ....*....|....*....|....*....|....
gi 15079243   230 LSALRLSEQLREKEEQILALEADMTKWEQKYLEE 263
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAE 1725
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
18-214 9.81e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 9.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     18 LQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRR-LQDFNRDLRERLESANRRLASKT 96
Cdd:pfam12128  335 LDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRdIAGIKDKLAKIREARDRQLAVAE 414
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     97 QEAQAGSQDMVAKLlaqsyeqqqeqekleremallRGAIEDQRRRAELLEQALGNAQGRAARA---EEELRKKQAYVEKV 173
Cdd:pfam12128  415 DDLQALESELREQL---------------------EAGKLEFNEEEYRLKSRLGELKLRLNQAtatPELLLQLENFDERI 473
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 15079243    174 ERLQQALGQLQAACEKREQLELRLRTRLEQELKAL-----RAQQRQ 214
Cdd:pfam12128  474 ERAREEQEAANAEVERLQSELRQARKRRDQASEALrqasrRLEERQ 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-326 1.16e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     27 EKAGRIEKLESEIQRLSEAHESLTRAsskrealektmRNKMDSEMRRLQDFNRDLRERLESANRRLASktqeaqagsqdm 106
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKA-----------LAELRKELEELEEELEQLRKELEELSRQISA------------ 730
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    107 vakLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAA 186
Cdd:TIGR02168  731 ---LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    187 CEKREQLELRLRTRLEQELKALRAQ-QRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWeqkyLEERA 265
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRiAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERA 883
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15079243    266 MRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEK 326
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
 
Name Accession Description Interval E-value
Angiomotin_C pfam12240
Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 ...
169-374 1.05e-92

Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.


Pssm-ID: 463503 [Multi-domain]  Cd Length: 200  Bit Score: 279.34  E-value: 1.05e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   169 YVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGsggspELSALRLSEQLREKEEQILA 248
Cdd:pfam12240   1 YVEKVERLQQALAQLQAACEKREQLELRLRTRLEQELKSLRAQQRQGGSQGSGPS-----EYSAPALMELLREKEERILA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   249 LEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDA 328
Cdd:pfam12240  76 LEADMTKWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRHSYDSSFNEELLLANRRCQEMENRIKNLHAQILEKDA 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 15079243   329 VIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFaAAAAGTQGWQGLSS 374
Cdd:pfam12240 156 MIKVLQQRSRKDPGKTDQQSLRPARSVPSIS-AAATGLHSRQTSLS 200
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
2-268 1.68e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.68e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   2 EAVLRENARLQRDNERLQRELES-SAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKtmrnkmdsEMRRLQDFNRD 80
Cdd:COG1196 242 EELEAELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--------DIARLEERRRE 313
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  81 LRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAE 160
Cdd:COG1196 314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 161 EELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLR 240
Cdd:COG1196 394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
                       250       260
                ....*....|....*....|....*...
gi 15079243 241 EKEEQILALEADMTKWEQKYLEERAMRQ 268
Cdd:COG1196 474 LLEAALAELLEELAEAAARLLLLLEAEA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
31-391 2.52e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.52e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  31 RIEKLESEIQRLSEAHESLTRassKREALEKTMRnKMDSEMRRLQDFNRDLRERLESANRRLASKTQEaqagsqdmVAKL 110
Cdd:COG1196 233 KLRELEAELEELEAELEELEA---ELEELEAELA-ELEAELEELRLELEELELELEEAQAEEYELLAE--------LARL 300
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 111 LAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQayvekvERLQQALGQLQAACEKR 190
Cdd:COG1196 301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAEAEL 374
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 191 EQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFA 270
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 271 MDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLtgghRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLR 350
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELA----EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
                       330       340       350       360
                ....*....|....*....|....*....|....*....|.
gi 15079243 351 PAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPARLTTDRA 391
Cdd:COG1196 531 GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA 571
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
2-260 1.56e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.56e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   2 EAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREAlektmrnkmdsEMRRLQDFNRDL 81
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE-----------ELEEAEEELEEA 356
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  82 RERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEE 161
Cdd:COG1196 357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 162 ELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPE-LSALRLSEQLR 240
Cdd:COG1196 437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgFLEGVKAALLL 516
                       250       260
                ....*....|....*....|
gi 15079243 241 EKEEQILALEADMTKWEQKY 260
Cdd:COG1196 517 AGLRGLAGAVAVLIGVEAAY 536
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
2-265 1.18e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243      2 EAVLRENARLQRDNERLQRELESSAEK----AGRIEKLESEIQRLSEAHESLTRASSK-REALEKTMRN-------KMDS 69
Cdd:TIGR02169  719 GEIEKEIEQLEQEEEKLKERLEELEEDlsslEQEIENVKSELKELEARIEELEEDLHKlEEALNDLEARlshsripEIQA 798
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     70 EMRRLQDFNRDLRERLESANRRLASKTQEAQAgSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQAL 149
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEY-LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    150 GNAQGRAARAEEELRKKQAyveKVERLQQALGQLQAACEKREQLELRLRTRLEqelkALRAQQRQAGAPGGSSGSGGSPE 229
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEA---QLRELERKIEELEAQIEKKRKRLSELKAKLE----ALEEELSEIEDPKGEDEEIPEEE 950
                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 15079243    230 LSALRLSEQLREKEEQILALEADMTKWEQKYLEERA 265
Cdd:TIGR02169  951 LSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLK 986
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
31-251 1.20e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   31 RIEKLESEIQRLSEAHESLTRASSKREALEktmrnkmdsemrRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKL 110
Cdd:COG4913  226 AADALVEHFDDLERAHEALEDAREQIELLE------------PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELL 293
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  111 LAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRA-ARAEEELRKKQayvEKVERLQQALGQLQAACek 189
Cdd:COG4913  294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLE---RELEERERRRARLEALL-- 368
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15079243  190 rEQLELRLRTRlEQELKALRAQQRQAGAPGGSSGSGGSPELSALR-----LSEQLREKEEQILALEA 251
Cdd:COG4913  369 -AALGLPLPAS-AEEFAALRAEAAALLEALEEELEALEEALAEAEaalrdLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
7-262 1.61e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 1.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243      7 ENARLQRDNERLQRELESSAEKAGRIEKLESEI-QRLSEAHESLTRASSKREALEKTmRNKMDSEMRRLQDFNRDLRERL 85
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELsQELSDASRKIGEIEKEIEQLEQE-EEKLKERLEELEEDLSSLEQEI 753
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     86 ESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAEL----LEQALGNAQGRAARAEE 161
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEArlreIEQKLNRLTLEKEYLEK 833
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    162 ELRKKQAYVEKVERlqqalgQLQAACEKREQLELRLRtRLEQELKALRAQQRQagapggssgsggspelsalrLSEQLRE 241
Cdd:TIGR02169  834 EIQELQEQRIDLKE------QIKSIEKEIENLNGKKE-ELEEELEELEAALRD--------------------LESRLGD 886
                          250       260
                   ....*....|....*....|.
gi 15079243    242 KEEQILALEADMTKWEQKYLE 262
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEE 907
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
10-262 2.89e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 2.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     10 RLQRDNERLQRELESSAEK--------AGRIEKLESEIQR----LSEAHESLTRASSKREALEKTMRnkmdsemrrlqdf 77
Cdd:TIGR02169  202 RLRREREKAERYQALLKEKreyegyelLKEKEALERQKEAierqLASLEEELEKLTEEISELEKRLE------------- 268
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     78 nrDLRERLESANRRLASKTQEAQAGSQDMVAKLLAqsyeqqqeqeklerEMALLRGAIEDQRRRAElleqalgNAQGRAA 157
Cdd:TIGR02169  269 --EIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA--------------EIASLERSIAEKERELE-------DAEERLA 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    158 RAEEELRKKQAYVEKVERLQQALG----QLQAACEKREQLELRLRTRLEQELKALRAqQRQAGAPGGSSGSGGSPELSAL 233
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERkrrdKLTEEYAELKEELEDLRAELEEVDKEFAE-TRDELKDYREKLEKLKREINEL 404
                          250       260       270
                   ....*....|....*....|....*....|....
gi 15079243    234 -----RLSEQLREKEEQILALEADMTKWEQKYLE 262
Cdd:TIGR02169  405 kreldRLQEELQRLSEELADLNAAIAGIEAKINE 438
PTZ00121 PTZ00121
MAEBL; Provisional
2-263 1.51e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     2 EAVLRENARLQRDNERLQRELESSAEKAGRIEKLEseiQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDL 81
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK---KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    82 RERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLE-----QALGNAQGRA 156
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEvmklyEEEKKMKAEE 1611
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   157 ARAEEELRKKQAYVEKVERLQQALGQLQA--ACEKREQLELR-----LRTRLEQELKALRAQQRQAGAPGGSSGSGGSPE 229
Cdd:PTZ00121 1612 AKKAEEAKIKAEELKKAEEEKKKVEQLKKkeAEEKKKAEELKkaeeeNKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691
                         250       260       270
                  ....*....|....*....|....*....|....
gi 15079243   230 LSALRLSEQLREKEEQILALEADMTKWEQKYLEE 263
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAE 1725
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
31-214 2.02e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   31 RIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKmDSEMRRLQDFNRDLRErLESANRRLASKTQEAQA--GSQDMVA 108
Cdd:COG4913  611 KLAALEAELAELEEELAEAEERLEALEAELDALQER-REALQRLAEYSWDEID-VASAEREIAELEAELERldASSDDLA 688
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  109 KLlaqsyeqqqeqeklEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQAlgQLQAACE 188
Cdd:COG4913  689 AL--------------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL--ELRALLE 752
                        170       180       190
                 ....*....|....*....|....*....|..
gi 15079243  189 KR------EQLELRLRTRLEQELKALRAQQRQ 214
Cdd:COG4913  753 ERfaaalgDAVERELRENLEERIDALRARLNR 784
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1-260 2.51e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 2.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243      1 MEAVLRENARLQRDNERLQRELESSAEkagRIEKLESEIQRLSEAHESLtrasSKREALEKTMRNKMDSEMRRLQDFNRD 80
Cdd:TIGR02169  296 IGELEAEIASLERSIAEKERELEDAEE---RLAKLEAEIDKLLAEIEEL----EREIEEERKRRDKLTEEYAELKEELED 368
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     81 LRERLESanrrLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRraelLEQALGNAQGRAARAE 160
Cdd:TIGR02169  369 LRAELEE----VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD----LNAAIAGIEAKINELE 440
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    161 EELRKKQAYVEKVErlqQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLR 240
Cdd:TIGR02169  441 EEKEDKALEIKKQE---WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517
                          250       260
                   ....*....|....*....|
gi 15079243    241 EKEEQILALEADMTKWEQKY 260
Cdd:TIGR02169  518 ASIQGVHGTVAQLGSVGERY 537
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
23-245 4.45e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.45e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  23 ESSAEKAGRIEKLESEIQRLSEAhesLTRASSKREALEKTmRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAG 102
Cdd:COG4942  20 DAAAEAEAELEQLQQEIAELEKE---LAALKKEEKALLKQ-LAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 103 SQDMVA--KLLAQSYEQQQEQEKLEREMALLRGA-IEDQRRRAELLEQAlgnAQGRAARAEEELRKKQAYVEKVERLQQA 179
Cdd:COG4942  96 RAELEAqkEELAELLRALYRLGRQPPLALLLSPEdFLDAVRRLQYLKYL---APARREQAEELRADLAELAALRAELEAE 172
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15079243 180 LGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQ 245
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
18-214 9.81e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 9.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     18 LQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRR-LQDFNRDLRERLESANRRLASKT 96
Cdd:pfam12128  335 LDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRdIAGIKDKLAKIREARDRQLAVAE 414
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     97 QEAQAGSQDMVAKLlaqsyeqqqeqekleremallRGAIEDQRRRAELLEQALGNAQGRAARA---EEELRKKQAYVEKV 173
Cdd:pfam12128  415 DDLQALESELREQL---------------------EAGKLEFNEEEYRLKSRLGELKLRLNQAtatPELLLQLENFDERI 473
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 15079243    174 ERLQQALGQLQAACEKREQLELRLRTRLEQELKAL-----RAQQRQ 214
Cdd:pfam12128  474 ERAREEQEAANAEVERLQSELRQARKRRDQASEALrqasrRLEERQ 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-326 1.16e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243     27 EKAGRIEKLESEIQRLSEAHESLTRAsskrealektmRNKMDSEMRRLQDFNRDLRERLESANRRLASktqeaqagsqdm 106
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKA-----------LAELRKELEELEEELEQLRKELEELSRQISA------------ 730
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    107 vakLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAA 186
Cdd:TIGR02168  731 ---LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    187 CEKREQLELRLRTRLEQELKALRAQ-QRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWeqkyLEERA 265
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRiAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERA 883
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15079243    266 MRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEK 326
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
128-259 1.37e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.37e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243 128 MALLRGAIEDQRRRAELLEQALGNAQG---RAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQE 204
Cdd:COG1196 634 AALRRAVTLAGRLREVTLEGEGGSAGGsltGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15079243 205 LKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQK 259
Cdd:COG1196 714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
137-264 1.73e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  137 DQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQ----------AACEKREQLELRLR-------- 198
Cdd:COG4913  607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidvaSAEREIAELEAELErldassdd 686
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15079243  199 -TRLEQELKALRAQQRQAGAPGGSSGSGGSPELSAL-RLSEQLREKEEQILALEADMTKWEQKYLEER 264
Cdd:COG4913  687 lAALEEQLEELEAELEELEEELDELKGEIGRLEKELeQAEEELDELQDRLEAAEDLARLELRALLEER 754
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
7-214 3.49e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.75  E-value: 3.49e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243   7 ENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLE 86
Cdd:COG4942  21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243  87 SANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKlereMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKK 166
Cdd:COG4942 101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRR----LQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15079243 167 QAYVEKVERLQQALGQLQAACEK------------REQLE--LRLRTRLEQELKALRAQQRQ 214
Cdd:COG4942 177 EALLAELEEERAALEALKAERQKllarlekelaelAAELAelQQEAEELEALIARLEAEAAA 238
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
131-339 4.65e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    131 LRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALrA 210
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL-E 760
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15079243    211 QQRQAGAPGGSSGSGGSPELSALR--LSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRH 288
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIeeLEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 15079243    289 SPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRR 339
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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