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Conserved domains on  [gi|14043289|gb|AAH07639|]
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ATG4D protein [Homo sapiens]

Protein Classification

cysteine protease ATG4( domain architecture ID 3047)

cysteine protease ATG4 is required in the cytoplasm for vacuole transport (Cvt) and autophagy

EC:  3.4.22.-
Gene Ontology:  GO:0019786|GO:0006914|GO:0008234|GO:0051697|GO:0006508
MEROPS:  C54
PubMed:  11517925

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_C54 super family cl04056
Peptidase family C54;
1-78 4.14e-49

Peptidase family C54;


The actual alignment was detected with superfamily member pfam03416:

Pssm-ID: 460915  Cd Length: 269  Bit Score: 158.05  E-value: 4.14e-49
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 14043289     1 MGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSE 78
Cdd:pfam03416 192 IGGRPSSSLYFVGFQGDKLIYLDPHTTQPAVDVSYTDFDLESYHCKRPRKMPISKMDPSMALGFYCRDEEDFEDFCSR 269
 
Name Accession Description Interval E-value
Peptidase_C54 pfam03416
Peptidase family C54;
1-78 4.14e-49

Peptidase family C54;


Pssm-ID: 460915  Cd Length: 269  Bit Score: 158.05  E-value: 4.14e-49
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 14043289     1 MGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSE 78
Cdd:pfam03416 192 IGGRPSSSLYFVGFQGDKLIYLDPHTTQPAVDVSYTDFDLESYHCKRPRKMPISKMDPSMALGFYCRDEEDFEDFCSR 269
 
Name Accession Description Interval E-value
Peptidase_C54 pfam03416
Peptidase family C54;
1-78 4.14e-49

Peptidase family C54;


Pssm-ID: 460915  Cd Length: 269  Bit Score: 158.05  E-value: 4.14e-49
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 14043289     1 MGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSE 78
Cdd:pfam03416 192 IGGRPSSSLYFVGFQGDKLIYLDPHTTQPAVDVSYTDFDLESYHCKRPRKMPISKMDPSMALGFYCRDEEDFEDFCSR 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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