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Conserved domains on  [gi|52790425|gb|AAH05190|]
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HIBCH protein, partial [Homo sapiens]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
70-361 3.67e-171

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 479.66  E-value: 3.67e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    70 AGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV-FFREEYML 148
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   149 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 228
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   229 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFILEEHMDKINSCFSANTVEEIIENL 308
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 52790425   309 QQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 361
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCL 292
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
70-361 3.67e-171

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 479.66  E-value: 3.67e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    70 AGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV-FFREEYML 148
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   149 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 228
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   229 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFILEEHMDKINSCFSANTVEEIIENL 308
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 52790425   309 QQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 361
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCL 292
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
58-361 3.91e-131

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 378.39  E-value: 3.91e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKI 137
Cdd:PRK05617   1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 216
Cdd:PRK05617  81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  217 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfiLEEHMDKINSC 295
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52790425  296 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 361
Cdd:PRK05617 236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAML 301
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
62-246 1.15e-59

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 190.85  E-value: 1.15e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIApVF 141
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425 142 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 220
Cdd:cd06558  79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                       170       180
                ....*....|....*....|....*.
gi 52790425 221 LTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:cd06558 159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
62-259 6.18e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 157.25  E-value: 6.18e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQkiAPVF 141
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEE--ARAF 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425 142 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 220
Cdd:COG1024  78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 52790425 221 LTGFRLKGRDVYRAGIATHFVDSEKL-----AMLEEdlLALKSP 259
Cdd:COG1024 158 LTGRRIDAEEALELGLVNRVVPDDELlaaalALAAR--LAAGPP 199
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
50-246 1.17e-14

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 72.96  E-value: 1.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    50 LRMSKHTDAAEEvllekkgcagvITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 129
Cdd:TIGR01929   4 IRYEKSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRGD 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   130 AEKAKQKIAPVFFREEymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP 209
Cdd:TIGR01929  73 YGYIDDSGVHRLNVLD--VQRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMA 150
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 52790425   210 RLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:TIGR01929 151 RIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
70-361 3.67e-171

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 479.66  E-value: 3.67e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    70 AGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV-FFREEYML 148
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   149 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 228
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   229 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFILEEHMDKINSCFSANTVEEIIENL 308
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 52790425   309 QQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 361
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCL 292
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
58-361 3.91e-131

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 378.39  E-value: 3.91e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKI 137
Cdd:PRK05617   1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 216
Cdd:PRK05617  81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  217 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfiLEEHMDKINSC 295
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52790425  296 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 361
Cdd:PRK05617 236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAML 301
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
58-361 1.07e-94

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 287.08  E-value: 1.07e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKI 137
Cdd:PLN02874   9 AEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGRESDDSC 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 APVFFREeYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGY 217
Cdd:PLN02874  88 LEVVYRM-YWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  218 FLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKsfILEEhMDKINSCFS 297
Cdd:PLN02874 167 YLALTGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFSKDVQADEDS--ILNK-QSWINECFS 243
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 52790425  298 ANTVEEIIENLQ----QDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACM 361
Cdd:PLN02874 244 KDTVEEIIKAFEseasKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNIL 311
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
52-356 2.14e-77

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 243.09  E-value: 2.14e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   52 MSKHTDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDIR-VISEA 130
Cdd:PLN02988   1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKG-HGRAFCAGGDVAaVVRDI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  131 EKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 210
Cdd:PLN02988  80 EQGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  211 LQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFileEHMD 290
Cdd:PLN02988 160 LPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAY---HRLD 236
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  291 KINSCFSANTVEEIIENLQ----QDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRL 356
Cdd:PLN02988 237 VIDRCFSRRTVEEIISALEreatQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRM 306
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
42-357 4.62e-72

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 229.87  E-value: 4.62e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   42 RTNTILHHLRMS------KHTDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGg 115
Cdd:PLN02851  18 RFGSVSYGRSFSalpnyaANDDLQDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  116 KAFCAGGDIRVISEA-EKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPET 194
Cdd:PLN02851  97 RAFCSGADVVSLYHLiNEGNVEECKLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEV 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  195 AIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHte 274
Cdd:PLN02851 177 QMGFHPDAGASYYLSRLPGYLGEYLALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQYG-- 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  275 SKIDRDKSFILEEhMDKINSCFSANTVEEIIENLQQDGSS----FALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVL 350
Cdd:PLN02851 255 DLVYPDKSSVLHK-IETIDKCFGHDTVEEIIEALENEAASsydeWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCL 333

                 ....*..
gi 52790425  351 TMEYRLS 357
Cdd:PLN02851 334 AREYRIS 340
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
29-357 3.80e-67

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 217.24  E-value: 3.80e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   29 EMWRLmsrfnAFKRTntiLHHLRMSKHtDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 108
Cdd:PLN02157  15 KLWRF-----GYRRS---FCSLKLTPE-DLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  109 IIKGAGgKAFCAGGDIRVISEAE-KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKC 187
Cdd:PLN02157  86 MMKGSG-RAFCAGGDIVSLYHLRkRGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRT 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  188 LFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASV 267
Cdd:PLN02157 165 IFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESC 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  268 LENYhteSKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGS----SFALEQLKVINKMSPTSLKITLRQLMEGSS 343
Cdd:PLN02157 245 LEKC---AEVAHPEKTGVIRRIDLLEKCFSHDTVEEIIDSLEIEAGrrkdTWCITTLRRLKESSPLSLKVALRSIREGRL 321
                        330
                 ....*....|....
gi 52790425  344 KTLQEVLTMEYRLS 357
Cdd:PLN02157 322 QTLDQCLIREYRMS 335
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
62-246 1.15e-59

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 190.85  E-value: 1.15e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIApVF 141
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425 142 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 220
Cdd:cd06558  79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                       170       180
                ....*....|....*....|....*.
gi 52790425 221 LTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:cd06558 159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
62-259 6.18e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 157.25  E-value: 6.18e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQkiAPVF 141
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEE--ARAF 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425 142 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 220
Cdd:COG1024  78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 52790425 221 LTGFRLKGRDVYRAGIATHFVDSEKL-----AMLEEdlLALKSP 259
Cdd:COG1024 158 LTGRRIDAEEALELGLVNRVVPDDELlaaalALAAR--LAAGPP 199
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
61-257 1.56e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 124.98  E-value: 1.56e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   61 EVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIrviSEAEKAKQKIAPV 140
Cdd:PRK06688   6 DLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGR-AFSAGGDI---KDFPKAPPKPPDE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  141 FfREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLqgkLGYF-- 218
Cdd:PRK06688  82 L-APVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRL---IGRAra 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 52790425  219 --LALTGFRLKGRDVYRAGIATHFV-DSEKLAmlEEDLLALK 257
Cdd:PRK06688 158 aeMLLLGEPLSAEEALRIGLVNRVVpAAELDA--EADAQAAK 197
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
62-265 8.49e-27

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 106.75  E-value: 8.49e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS-----EAEKAKQK 136
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKdlneeEGRKFGLL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  137 IAPVFFREEYMlnnavgscQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KL 215
Cdd:PRK05809  86 GNKVFRKLENL--------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGpGK 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 52790425  216 GYFLALTGFRLKGRDVYRAGIATHFVDSEKLaMLEEDLLALKSPSKENIA 265
Cdd:PRK05809 158 AKELIYTGDMINAEEALRIGLVNKVVEPEKL-MEEAKALANKIAANAPIA 206
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
52-255 1.04e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 104.02  E-value: 1.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   52 MSKHTDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 131
Cdd:PRK06127   3 MSSISSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  132 KAKQKIAPVFFREEYMLnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdvGGGY-FLPR 210
Cdd:PRK06127  83 SDAEAVAAYEQAVEAAQ-AALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL----GYGYdGVKN 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 52790425  211 LQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA 255
Cdd:PRK06127 158 LVDLVGPSAAkdlfYTARRFDAAEALRIGLVHRVTAADDLETALADYAA 206
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
65-246 2.58e-25

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 102.44  E-value: 2.58e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    65 EKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAKQKIapvfFRE 144
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQAL----YRE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   145 EYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALT 222
Cdd:pfam00378  76 NVLdLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLL 155
                         170       180
                  ....*....|....*....|....
gi 52790425   223 GFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:pfam00378 156 GRRISAQEALKWGLVDKVVPEDQL 179
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
61-236 4.21e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 102.16  E-value: 4.21e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   61 EVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE--AEKAKQKIA 138
Cdd:PRK06072   1 MIKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPdfAIDLRETFY 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  139 PVFfREeymlnnaVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF 218
Cdd:PRK06072  80 PII-RE-------IRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYE 151
                        170
                 ....*....|....*...
gi 52790425  219 LALTGFRLKGRDVYRAGI 236
Cdd:PRK06072 152 ILVLGGEFTAEEAERWGL 169
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
71-269 4.28e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 102.12  E-value: 4.28e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   71 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI--RVISEAEKAKQKIAPVffrEEYMl 148
Cdd:PRK07657  15 VKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLkeRAGMNEEQVRHAVSLI---RTTM- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  149 nNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLK 227
Cdd:PRK07657  91 -EMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRIS 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 52790425  228 GRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIASVLE 269
Cdd:PRK07657 170 AQEAKEIGLVEFVVPAHLLEEKAIEIaekIASNGPiavrqAKEAISNGIQ 219
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
57-244 5.84e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 102.05  E-value: 5.84e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   57 DAAEEVLLEK--KGCAgVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAK 134
Cdd:PRK08138   4 TATDVVLLERpaDGVA-LLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATAGAIE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  135 qkiapVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK 214
Cdd:PRK08138  82 -----MYLRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGK 156
                        170       180       190
                 ....*....|....*....|....*....|.
gi 52790425  215 L-GYFLALTGFRLKGRDVYRAGIATHFVDSE 244
Cdd:PRK08138 157 FkAMRMALTGCMVPAPEALAIGLVSEVVEDE 187
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
62-269 2.31e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 100.12  E-value: 2.31e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRviSEAEKAKQKIAPVF 141
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLK--EQAAGGKRGWPESG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  142 FreeymlnnavGS------CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR---LQ 212
Cdd:PRK06494  84 F----------GGltsrfdLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRqigLK 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52790425  213 GKLGYFlaLTGFRLKGRDVYRAGIATHFV-DSEKLAMLE---EDLLALkSP-----SKENIASVLE 269
Cdd:PRK06494 154 RAMGMI--LTGRRVTAREGLELGFVNEVVpAGELLAAAErwaDDILAC-SPlsiraSKQAVYRGLE 216
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
58-255 7.47e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 98.96  E-value: 7.47e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviseaEKAKQKI 137
Cdd:PRK05862   2 AYETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIK-----EMADLSF 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 APVfFREEYMLN-NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 216
Cdd:PRK05862  76 MDV-YKGDYITNwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAK 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 52790425  217 YF-LALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDLLA 255
Cdd:PRK05862 155 AMdLCLTGRMMDAAEAERAGLVSRVVPADKL--LDEALAA 192
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
59-223 2.88e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 97.14  E-value: 2.88e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   59 AEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIA 138
Cdd:PRK05980   2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  139 PV-FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLG 216
Cdd:PRK05980  82 LRdFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrKRA 161

                 ....*..
gi 52790425  217 YFLALTG 223
Cdd:PRK05980 162 LELLLTG 168
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
72-259 7.97e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 87.44  E-value: 7.97e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   72 VITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEK------AKQKIAPVFFree 145
Cdd:PRK06495  16 VVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKgpgdlrAHNRRTRECF--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  146 ymlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdVGGGYFLPRLQGK-LGYFLALTGF 224
Cdd:PRK06495  91 ----HAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHsLTRRMMLTGY 163
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 52790425  225 RLKGRDVYRAGIATHFVDSEKL---AMLEEDLLALKSP 259
Cdd:PRK06495 164 RVPAAELYRRGVIEACLPPEELmpeAMEIAREIASKSP 201
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
59-250 9.11e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 87.47  E-value: 9.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   59 AEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEA--EKAKQK 136
Cdd:PRK05870   2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGAApgRPAEDG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  137 IAPVFfrEEYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KL 215
Cdd:PRK05870  81 LRRIY--DGFL---AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGpQV 155
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 52790425  216 GYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 250
Cdd:PRK05870 156 ARAALLFGMRFDAEAAVRHGLALMVADDPVAAALE 190
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
64-269 1.04e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 87.38  E-value: 1.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   64 LEKKGCAGVITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVI------SEAEKAKQKI 137
Cdd:PRK07658   6 VRVEDHVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFtsvteaEQATELAQLG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 APVFFREEymlnnavgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-G 216
Cdd:PRK07658  84 QVTFERVE--------KFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAkA 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 52790425  217 YFLALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDL-----LALKSPskENIASVLE 269
Cdd:PRK07658 156 LEMMLTSEPITGAEALKWGLVNGVFPEETL--LDDAKklakkIAGKSP--ATTRAVLE 209
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
60-260 2.78e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 86.13  E-value: 2.78e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDI---RVISEAEKAKQK 136
Cdd:PRK05995   4 ETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDENR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  137 IAPVFFREeyMLNnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVgggyFLPRLQGKLG 216
Cdd:PRK05995  83 ADARRLAD--MLR-AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPAT----ISPYVIRAMG 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 52790425  217 ------YFlaLTGFRLKGRDVYRAGIATHFVDSEKL-AMLEEDLLAL--KSPS 260
Cdd:PRK05995 156 eraarrYF--LTAERFDAAEALRLGLVHEVVPAEALdAKVDELLAALvaNSPQ 206
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
73-259 3.63e-19

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 86.11  E-value: 3.63e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE-------------AEKAKQKIAp 139
Cdd:PLN02664  21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKTLNSiseqsssgdrgrsGERLRRKIK- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  140 vfFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYF- 218
Cdd:PLN02664  99 --FLQDAI--TAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGYGn 171
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 52790425  219 ---LALTGFRLKGRDVYRAG-IATHFVDSEKL---AMLEEDLLALKSP 259
Cdd:PLN02664 172 ameLALTGRRFSGSEAKELGlVSRVFGSKEDLdegVRLIAEGIAAKSP 219
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
58-246 4.92e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 85.41  E-value: 4.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRvisEAEKAKQKI 137
Cdd:PRK06190   2 TEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGA-DPAFCAGLDLK---ELGGDGSAY 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 APVFFREEymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLG 216
Cdd:PRK06190  78 GAQDALPN--PSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGiGRA 155
                        170       180       190
                 ....*....|....*....|....*....|
gi 52790425  217 YFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK06190 156 RRMSLTGDFLDAADALRAGLVTEVVPHDEL 185
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
55-192 7.19e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 85.04  E-value: 7.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   55 HTDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAK 134
Cdd:PRK06144   3 MTTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAE 82
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 52790425  135 QKIAPVFFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 192
Cdd:PRK06144  83 DAVAYERRIDRVL--GALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
73-246 1.75e-18

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 83.98  E-value: 1.75e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFF---REEYMLN 149
Cdd:PRK03580  16 ITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFaglTEIFDLD 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  150 navgscqKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFR 225
Cdd:PRK03580  95 -------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPK---RLPPAIAnemvMTGRR 164
                        170       180
                 ....*....|....*....|.
gi 52790425  226 LKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK03580 165 MDAEEALRWGIVNRVVPQAEL 185
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
73-259 2.97e-18

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 83.28  E-value: 2.97e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRviseaEKAKQKIAPVFFREEYMLNNAV 152
Cdd:PRK09674  15 LTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNA-RFFAAGADLN-----EMAEKDLAATLNDPRPQLWQRL 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  153 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDV 231
Cdd:PRK09674  89 QAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKsLASQMVLTGESITAQQA 168
                        170       180       190
                 ....*....|....*....|....*....|.
gi 52790425  232 YRAGIATHFVDSE---KLAMLEEDLLALKSP 259
Cdd:PRK09674 169 QQAGLVSEVFPPEltlERALQLASKIARHSP 199
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
59-242 1.39e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 78.61  E-value: 1.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   59 AEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQ--- 135
Cdd:PRK07799   4 GPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG-AFCAGMDLKAATKKPPGDSfkd 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  136 -KIAPVffREEYMLNNAvgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpRLQGK 214
Cdd:PRK07799  83 gSYDPS--RIDALLKGR--RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAV--RLVRQ 155
                        170       180       190
                 ....*....|....*....|....*....|..
gi 52790425  215 LGYFLA----LTGFRLKGRDVYRAGIATHFVD 242
Cdd:PRK07799 156 IPYTVAcdllLTGRHITAAEAKEIGLIGHVVP 187
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
56-266 3.35e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 77.38  E-value: 3.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   56 TDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDpETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQ 135
Cdd:PRK07659   2 TSKMESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAES-SAHIVVLRGNG-RGFSAGGDIKMMLSSNDESK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  136 KIAPVFFREEYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKL 215
Cdd:PRK07659  80 FDGVMNTISEIVV--TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK---RV 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 52790425  216 GYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA-LKSPSKENIAS 266
Cdd:PRK07659 155 GENKAkqiiWEGKKLSATEALDLGLIDEVIGGDFQTAAKQKISEwLQKPLKAMIET 210
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
62-246 3.49e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 77.32  E-value: 3.49e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAGVITLNRPKFLNALTLN-MIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAkQKIAPV 140
Cdd:PRK09245   5 LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDMRARVGA-FGGSPA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  141 FFREEY-----MLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 214
Cdd:PRK09245  83 DIRQGYrhgiqRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGmA 162
                        170       180       190
                 ....*....|....*....|....*....|..
gi 52790425  215 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK09245 163 RAAEMAFTGDAIDAATALEWGLVSRVVPADQL 194
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
58-237 4.83e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 76.95  E-value: 4.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKakqki 137
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGG-TFCAGMDLKAFARGER----- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 apVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGY 217
Cdd:PRK08252  75 --PSIPGRGFGGLTERPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGG---LLRLPRRIPY 149
                        170       180
                 ....*....|....*....|....
gi 52790425  218 FLA----LTGFRLKGRDVYRAGIA 237
Cdd:PRK08252 150 HIAmelaLTGDMLTAERAHELGLV 173
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
73-213 2.88e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 75.43  E-value: 2.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM----- 147
Cdd:PRK08260  17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLSAGGNTFDLDAPRTPVEADEEDRadpsd 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 52790425  148 ---------LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 213
Cdd:PRK08260  96 dgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
56-260 3.01e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 74.74  E-value: 3.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   56 TDAAEEVLLEKKGCA-GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDI---RVISEAE 131
Cdd:PRK06210   1 DMAYDAVLYEVADSGvAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGA-GRGFCAGADMgelQTIDPSD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  132 KAKQKIAPVFF---REEYMLNNA-VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 207
Cdd:PRK06210  80 GRRDTDVRPFVgnrRPDYQTRYHfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWI 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 52790425  208 LPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL--AMLE--EDLLALKSPS 260
Cdd:PRK06210 160 LPRLVGHANALdLLLSARTFYAEEALRLGLVNRVVPPDELmeRTLAyaEDLARNVSPA 217
PLN02600 PLN02600
enoyl-CoA hydratase
72-241 4.83e-15

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 74.07  E-value: 4.83e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   72 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV-----ISEAEKAKQKIAPVFfreey 146
Cdd:PLN02600   7 ELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKErrkmsPSEVQKFVNSLRSTF----- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  147 mlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFR 225
Cdd:PLN02600  82 ---SSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAKELIFTGRR 158
                        170
                 ....*....|....*.
gi 52790425  226 LKGRDVYRAGIATHFV 241
Cdd:PLN02600 159 IGAREAASMGLVNYCV 174
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
60-231 4.84e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 74.24  E-value: 4.84e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIyPQLKKW-EQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIA 138
Cdd:PRK06142   6 ESFTVELADHVAQVTLNRPGKGNAMNPAFWSEL-PEIFRWlDADPEVRAVVLSGSG-KHFSYGIDLPAMAGVFGQLGKDG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  139 PVFFREEY------MLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 210
Cdd:PRK06142  84 LARPRTDLrreilrLQAaiNAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPR 163
                        170       180
                 ....*....|....*....|...
gi 52790425  211 LQGKlGYF--LALTgfrlkGRDV 231
Cdd:PRK06142 164 IIGD-GHLreLALT-----GRDI 180
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
59-299 6.83e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 73.49  E-value: 6.83e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   59 AEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEaekaKQKIA 138
Cdd:PRK07511   2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGG-FFCAGGNLNRLLE----NRAKP 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  139 PVFFREEY-MLNN---AVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR-LQG 213
Cdd:PRK07511  77 PSVQAASIdGLHDwirAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLPR 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  214 KLGYFLALTGFRLKGRDVYRAGIATHFVD-----SEKLAMLEEdlLALKSP-SKENIASVLENYHTESkidrdksfiLEE 287
Cdd:PRK07511 157 QLATELLLEGKPISAERLHALGVVNRLAEpgqalAEALALADQ--LAAGSPnALARIKSLIADAPEAT---------LAA 225
                        250
                 ....*....|..
gi 52790425  288 HMDKINSCFSAN 299
Cdd:PRK07511 226 QLEAERDHFVAS 237
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
50-246 1.17e-14

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 72.96  E-value: 1.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    50 LRMSKHTDAAEEvllekkgcagvITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 129
Cdd:TIGR01929   4 IRYEKSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRGD 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   130 AEKAKQKIAPVFFREEymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP 209
Cdd:TIGR01929  73 YGYIDDSGVHRLNVLD--VQRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMA 150
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 52790425   210 RLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:TIGR01929 151 RIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
62-223 1.25e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 72.76  E-value: 1.25e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAgVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKqkiAPVF 141
Cdd:PRK06143  10 VTRDDRGVA-TLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQAS---AEAF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  142 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfPDVGGGYFLPRLQGKL-GYFLA 220
Cdd:PRK06143  86 ISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWArTRWLL 164

                 ...
gi 52790425  221 LTG 223
Cdd:PRK06143 165 LTG 167
PLN02888 PLN02888
enoyl-CoA hydratase
52-246 1.69e-14

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 72.48  E-value: 1.69e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   52 MSKHTDAAEEVLLEK-KGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEA 130
Cdd:PLN02888   1 TMTQTVSENLILVPKsRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGS-GRAFCSGVDLTAAEEV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  131 EKAKQKIA---PVFFREEymlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 207
Cdd:PLN02888  80 FKGDVKDVetdPVAQMER---------CRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQK 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 52790425  208 LPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PLN02888 151 LSRIIGaNRAREVSLTAMPLTAETAERWGLVNHVVEESEL 190
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
65-242 2.19e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 74.49  E-value: 2.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425    65 EKKGCAGVITLNRPKF-LNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIsEAEKAKQKIAPVFFR 143
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMI-AACKTAQEVTQLSQE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   144 EEYMLNNAVGScQKPYVALIHGITMGGGVGLSVHGQFRVATE--KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LA 220
Cdd:TIGR02441  97 GQEMFERIEKS-QKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALdMM 175
                         170       180
                  ....*....|....*....|..
gi 52790425   221 LTGFRLKGRDVYRAGIATHFVD 242
Cdd:TIGR02441 176 LTGKKIRADRAKKMGIVDQLVD 197
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
62-259 2.62e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 71.84  E-value: 2.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKK-GCAGViTLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRviSEAEKAKQKIAPV 140
Cdd:PRK07509   5 VSVTIEdGIADV-RLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGG-AFCAGLDVK--SVASSPGNAVKLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  141 FFREEYMLNNAvgscQK----------PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 210
Cdd:PRK07509  81 FKRLPGNANLA----QRvslgwrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRG 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 52790425  211 LQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS---EKLAMLEEdlLALKSP 259
Cdd:PRK07509 157 LVRKdVARELTYTARVFSAEEALELGLVTHVSDDplaAALALARE--IAQRSP 207
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
71-247 3.35e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 71.63  E-value: 3.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   71 GV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIAPVFFREEYML 148
Cdd:PRK07468  14 GVatLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTADRATRIEEARRLAMM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  149 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 228
Cdd:PRK07468  93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMSARLFDA 172
                        170
                 ....*....|....*....
gi 52790425  229 RDVYRAGIATHFVDSEKLA 247
Cdd:PRK07468 173 EEAVRLGLLSRVVPAERLD 191
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
60-254 6.72e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 70.54  E-value: 6.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKgAGGKAFCAGGDIRVISEAEKAKQ---- 135
Cdd:PRK07260   2 EHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLIN-ANGKVFSVGGDLVEMKRAVDEDDvqsl 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  136 -KIAPVFFREEYmlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG- 213
Cdd:PRK07260  81 vKIAELVNEISF----AIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGl 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 52790425  214 KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLL 254
Cdd:PRK07260 157 NRATHLAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLL 197
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
47-247 1.64e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 70.00  E-value: 1.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   47 LHHLRMSKHTDAAEEVLLEKKGCAGVITLNRPKFLNALTLnmirQIYPQLKKW----EQDPETFLIIIKGAGGkAFCAGG 122
Cdd:PRK08258   4 FRGSKRPLAGYEARHFLWEVDDGVATITLNRPERKNPLTF----ESYAELRDLfrelVYADDVKAVVLTGAGG-NFCSGG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  123 DIR-VISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF-P 200
Cdd:PRK08258  79 DVHeIIGPLTKMDMPELLAFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgA 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 52790425  201 DVGGGYFLPRL--QGKLGYFLaLTGFRLKGRDVYRAGIATHFVDSEKLA 247
Cdd:PRK08258 159 DMGACALLPRIigQGRASELL-YTGRSMSAEEGERWGFFNRLVEPEELL 206
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
60-247 2.16e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 69.17  E-value: 2.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEqDPETFLIIIKGAgGKAFCAGGDI--RVISEAEKAKQKI 137
Cdd:PRK08140   4 ETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGA-GRGFCAGQDLadRDVTPGGAMPDLG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  138 APVffrEEYM--LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK- 214
Cdd:PRK08140  82 ESI---ETFYnpLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMa 158
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 52790425  215 --LGyfLALTGFRLKGRDVYRAGIATHFVDSEKLA 247
Cdd:PRK08140 159 raLG--LALLGEKLSAEQAEQWGLIWRVVDDAALA 191
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
62-241 6.59e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 67.74  E-value: 6.59e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLkkwEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKA-----KQK 136
Cdd:PRK08150   4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAF---ARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGegmhhSRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  137 IAPVFFREEYmlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpdVGGG--YFLPRLQGK 214
Cdd:PRK08150  81 WHRVFDKIQY--------GRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIF--VGGGgsVRVPRLIGV 150
                        170       180
                 ....*....|....*....|....*...
gi 52790425  215 LGYF-LALTGFRLKGRDVYRAGIATHFV 241
Cdd:PRK08150 151 ARMTdMMLTGRVYDAQEGERLGLAQYLV 178
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
52-199 8.46e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 67.66  E-value: 8.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   52 MSKHTDAAEEVLLEKKGCAGVI--TLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISe 129
Cdd:PRK08139   1 MMAPAAATEAPLLLREDRDGVAtlTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAA-GKAFCAGHDLKEMR- 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 52790425  130 AEKAKQKIAPVFFR-EEYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF 199
Cdd:PRK08139  79 AARGLAYFRALFARcSRVMQ--AIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLF 147
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
60-213 1.37e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 66.87  E-value: 1.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAP 139
Cdd:PRK09076   3 IELDLEIDGHVAILTLNNPP-ANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMA 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 52790425  140 VFFREEY-MLNNAVGscqkPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 213
Cdd:PRK09076  82 RRFGEAFeALSAFRG----VSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVG 152
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
56-280 2.99e-12

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 65.86  E-value: 2.99e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   56 TDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQ 135
Cdd:PRK07827   2 TPVDTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGG-TFCAGADLSEAGGGGGDPY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  136 KIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL 215
Cdd:PRK07827  81 DAAVARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRA 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 52790425  216 G--YFlaLTGFRLKGRDVYRAGIATHFVDS--EKLAMLEEDlLALKSP-----SKE-NIASVLENYhteskiDRD 280
Cdd:PRK07827 161 AarYY--LTGEKFGAAEAARIGLVTAAADDvdAAVAALLAD-LRRGSPqglaeSKAlTTAAVLAGF------DRD 226
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
60-279 1.11e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 64.04  E-value: 1.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAG---VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIR----VISEAEK 132
Cdd:PRK06023   3 DHILVERPGAHPgvqVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEG-CFSAGNDMQdflaAAMGGTS 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  133 AKQKIAPVFFreeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ 212
Cdd:PRK06023  82 FGSEILDFLI--------ALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLM 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 52790425  213 GKLGYF--LALtGFRLKGRDVYRAGI-----ATHFVDSEKLAMLEEdlLALKSPSKENIASVLENYHTESKIDR 279
Cdd:PRK06023 154 GHQRAFalLAL-GEGFSAEAAQEAGLiwkivDEEAVEAETLKAAEE--LAAKPPQALQIARDLMRGPREDILAR 224
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
58-246 1.43e-11

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 63.98  E-value: 1.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   58 AAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDP-ETFLIIIKGAGgKAFCAG----------GDIRV 126
Cdd:PRK05981   2 QFKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAG-RGFCTGanlqgrgsggRESDS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  127 ISEAEKAKQKIAPVFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGY 206
Cdd:PRK05981  81 GGDAGAALETAYHPFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTW 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 52790425  207 FLPRLQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK05981 154 LLPRLVGKArAMELSLLGEKLPAETALQWGLVNRVVDDAEL 194
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
52-246 1.72e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 64.08  E-value: 1.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   52 MSKHTDAAEEVLLE--KKGCAgVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE 129
Cdd:PRK05864   1 VAGYRSTMSLVLVDhpRPEIA-LITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGA-GRGFSSGADHKSAGV 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  130 AEKAKQKIAPVF-FREEYMLNNAVGSCQK---PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF-PDVGG 204
Cdd:PRK05864  79 VPHVEGLTRPTYaLRSMELLDDVILALRRlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGL 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 52790425  205 GYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK05864 159 SYLLPRAIGSSRAFeIMLTGRDVDAEEAERIGLVSRQVPDEQL 201
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
71-273 5.25e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 62.35  E-value: 5.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   71 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK---AKQKIAPVFFReeym 147
Cdd:PRK11423  15 ATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVILRAPSGSKVWSAGHDIHELPSGGRdplSYDDPLRQILR---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  148 lnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYFLA----LTG 223
Cdd:PRK11423  91 ---MIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTNDAGFHIVkemfFTA 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 52790425  224 FRLKGRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIaSVLENYHT 273
Cdd:PRK11423 165 SPITAQRALAVGILNHVVEVEELEDFTLQMahhISEKAPlaiavIKEQL-RVLGEAHP 221
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
70-236 1.78e-10

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 62.22  E-value: 1.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   70 AGVITLNRP-KFLNALTLNMIRQIYPQLKKWEQDPEtfliiIKG---AGGKA--FCAGGDIRVISEAEKAKQkiAPVFFR 143
Cdd:PRK11154  16 IAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKE-----LKGvvfISGKPdnFIAGADINMLAACKTAQE--AEALAR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  144 EEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT--EKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 220
Cdd:PRK11154  89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGvSTALDMI 168
                        170
                 ....*....|....*.
gi 52790425  221 LTGFRLKGRDVYRAGI 236
Cdd:PRK11154 169 LTGKQLRAKQALKLGL 184
PLN02921 PLN02921
naphthoate synthase
56-213 3.02e-10

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 60.57  E-value: 3.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   56 TDAAEEVLLEK---KGCAGvITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 132
Cdd:PLN02921  61 GKEFTDIIYEKavgEGIAK-ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKDGY 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  133 AKQKIAPvffREEYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpDVG-GGYFLPR 210
Cdd:PLN02921 140 VGPDDAG---RLNVLdLQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMAR 215

                 ...
gi 52790425  211 LQG 213
Cdd:PLN02921 216 LVG 218
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
68-237 3.93e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 59.65  E-value: 3.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   68 GCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEqDPETFLIIIKGAGgKAFCAGGDIrviseaekAKQKIAPVFFREEYM 147
Cdd:PRK07854   8 GQVLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQG-TVFCAGADL--------SGDVYADDFPDALIE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  148 LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDvggGYFLPRLQGKLGYFLA----LTG 223
Cdd:PRK07854  78 MLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSLVGGGRAramlLGA 154
                        170
                 ....*....|....
gi 52790425  224 FRLKGRDVYRAGIA 237
Cdd:PRK07854 155 EKLTAEQALATGMA 168
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
51-267 4.55e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 60.06  E-value: 4.55e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   51 RMSKHTDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE- 129
Cdd:PRK08272   1 IRPVDLDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGA-GKGFCAGYDLSAYAEg 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  130 --AEKAKQKIAPVFFREEY--------MLNNAVGS-----------CQKPYVALIHGITMGGGVGLSVHGQFRVATEkcl 188
Cdd:PRK08272  80 ssSGGGGGAYPGKRQAVNHlpddpwdpMIDYQMMSrfvrgfmslwhAHKPTVAKVHGYCVAGGTDIALHCDQVIAAD--- 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  189 fampETAIGLFPD-VGG----GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLalkspskEN 263
Cdd:PRK08272 157 ----DAKIGYPPTrVWGvpatGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLV-------ER 225

                 ....
gi 52790425  264 IASV 267
Cdd:PRK08272 226 IAAV 229
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
60-171 6.37e-10

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 59.14  E-value: 6.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAP 139
Cdd:PRK07396  13 EDILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYGGYVDDDGVP 92
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 52790425  140 vffreeyMLN-----NAVGSCQKPYVALIHGITMGGG 171
Cdd:PRK07396  93 -------RLNvldlqRLIRTCPKPVIAMVAGYAIGGG 122
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
101-211 1.10e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 58.06  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  101 QDPETFLIIIKgAGGKAFCAGGDIRVISEAEKAKQKIAPVffREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 180
Cdd:PRK07938  42 ADPDTRVVVLR-AEGRGFNAGVDIKELQATPGFTALIDAN--RGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADV 118
                         90       100       110
                 ....*....|....*....|....*....|.
gi 52790425  181 RVATEKCLFAMPETAIGLfpdVGGGYFLPRL 211
Cdd:PRK07938 119 IVASDDATFGLPEVDRGA---LGAATHLQRL 146
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
62-244 1.62e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 57.66  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQKIAPVF 141
Cdd:PRK06563   1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAH-GEHFTAGLDLADVAPKLAAGGFPFPEG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  142 FREEYMLnnaVG-SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpRLQGKLGYFLA 220
Cdd:PRK06563  80 GIDPWGT---VGrRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILP-FGGATL--RFPQAAGWGNA 153
                        170       180
                 ....*....|....*....|....*...
gi 52790425  221 ----LTGFRLKGRDVYRAGIATHFVDSE 244
Cdd:PRK06563 154 mrylLTGDEFDAQEALRLGLVQEVVPPG 181
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
57-248 1.97e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 58.05  E-value: 1.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   57 DAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviseAEKAKQK 136
Cdd:PRK08290   1 MEYEYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGA-GKHFSAGHDLG----SGTPGRD 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  137 IAPVFFREEYMLNNAVG-----------------------SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPE 193
Cdd:PRK08290  76 RDPGPDQHPTLWWDGATkpgveqryarewevylgmcrrwrDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPV 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 52790425  194 TAIGLfpdVGGGYFL------PRlqgKLGYFLaLTGFRLKGRDVYRAGIATHFV-----DSEKLAM 248
Cdd:PRK08290 156 VRMGI---PGVEYFAhpwelgPR---KAKELL-FTGDRLTADEAHRLGMVNRVVprdelEAETLEL 214
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
61-259 2.91e-09

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 57.13  E-value: 2.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   61 EVLLEKKGCAgVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQKIAPV 140
Cdd:PRK05674   8 ELIRDPRGFA-TLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGR-GRHFSAGADLAWMQQSADLDYNTNLD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  141 FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLA 220
Cdd:PRK05674  86 DARELAELMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYA 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 52790425  221 LTGFRLKGRDVYRAG-IATHFVDSEKLAMLEE--DLLALKSP 259
Cdd:PRK05674 166 LTAERFDGRRARELGlLAESYPAAELEAQVEAwiANLLLNSP 207
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
73-246 5.19e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 56.57  E-value: 5.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIAPVfFREEYMLNNAV 152
Cdd:PRK07327  25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDFEVRARV-WREARDLVYNV 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  153 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGlfpdVGGG----YFLPRLQG--KLGYFLaLTGFRL 226
Cdd:PRK07327 103 INCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLG----VAAGdhaaIVWPLLCGmaKAKYYL-LLCEPV 177
                        170       180
                 ....*....|....*....|
gi 52790425  227 KGRDVYRAGIATHFVDSEKL 246
Cdd:PRK07327 178 SGEEAERIGLVSLAVDDDEL 197
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
60-246 2.83e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 54.58  E-value: 2.83e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAG----------GDIRVISE 129
Cdd:PRK12478   5 QTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGydfgggfqhwGEAMMTDG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  130 AEKAKQKIAPVFFRE-----EYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAI-GLFPDvg 203
Cdd:PRK12478  84 RWDPGKDFAMVTAREtgptqKFM---AIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLT-- 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 52790425  204 gGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK12478 159 -GMWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERL 200
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
62-213 3.36e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 50.61  E-value: 3.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   62 VLLEKKGCAGVITL--NRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDI---RVISEAEKAkqk 136
Cdd:PRK05869   8 VVSDGSQDAGLATLllSRPP-TNALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMpelRTLSAQEAD--- 82
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52790425  137 IAPVFFREEYmlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 213
Cdd:PRK05869  83 TAARVRQQAV---DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
158-213 1.25e-06

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 50.25  E-value: 1.25e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 52790425  158 PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 213
Cdd:PRK11730 104 PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
60-206 1.73e-06

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 49.05  E-value: 1.73e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG-----GKAFCAGGDIRVISeaekak 134
Cdd:COG0447  18 TDITYHRAEGIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGpskdgGWAFCSGGDQRVRG------ 91
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425 135 qkiapvffREEYMLNNAVG------------SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAmpETAiglfPDV 202
Cdd:COG0447  92 --------RGGYVYEDGVGrlnilevqrlirFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFG--QTG----PDV 157

                ....*..
gi 52790425 203 G---GGY 206
Cdd:COG0447 158 GsfdAGY 164
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
73-241 2.00e-06

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 48.43  E-value: 2.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQKiapvfFREEYMLNNAV 152
Cdd:PRK07110  18 VTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGY-PNYFATGGTQEGLLSLQTGKGT-----FTEANLYSLAL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  153 GsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFRLKG 228
Cdd:PRK07110  92 N-CPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPE---KLGLALGqemlLTARYYRG 167
                        170
                 ....*....|...
gi 52790425  229 RDVYRAGIATHFV 241
Cdd:PRK07110 168 AELKKRGVPFPVL 180
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
60-213 2.24e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 48.35  E-value: 2.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   60 EEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAkqkiap 139
Cdd:PRK08259   3 MSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADLKAVGTGRGN------ 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  140 vffREEYMLNNAVGSCQ----KPYVALIHGITMGGGVGLSVHGQFRVATEKCLFampetaiGLF------PDVGGGYF-L 208
Cdd:PRK08259  76 ---RLHPSGDGPMGPSRmrlsKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVF-------GVFcrrwgvPLIDGGTVrL 145

                 ....*
gi 52790425  209 PRLQG 213
Cdd:PRK08259 146 PRLIG 150
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
53-246 3.09e-05

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 45.00  E-value: 3.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   53 SKHTDAAEEVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDI-----RVI 127
Cdd:PRK09120   1 MSYENRWDTVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAG-DAWSAGMDLkeyfrETD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  128 SEAEKAKQKIApvffREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdvGGGY- 206
Cdd:PRK09120  80 AQPEILQERIR----REAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPP--GGGVs 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 52790425  207 -----FLPRLQgklGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 246
Cdd:PRK09120 154 kamadTVGHRD---ALYYIMTGETFTGRKAAEMGLVNESVPLAQL 195
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
73-265 1.53e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 42.75  E-value: 1.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425   73 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETflIIIKGAGgKAFCAGGDIRVISEAEKAKQKIApvfFREE--YMLNN 150
Cdd:PRK07112  17 LQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLP-EVFCFGADFSAIAEKPDAGRADL---IDAEplYDLWH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52790425  151 AVGScqKPYVALIH--GITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdvggGYFLPRLQGKLG----YFLALTGF 224
Cdd:PRK07112  91 RLAT--GPYVTIAHvrGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP----ACVLPFLIRRIGtqkaHYMTLMTQ 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 52790425  225 RLKGRDVYRAGIATHFV-DSEKLamLEEDLLALKSPSKENIA 265
Cdd:PRK07112 165 PVTAQQAFSWGLVDAYGaNSDTL--LRKHLLRLRCLNKAAVA 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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