NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|11118749|gb|AAG30424|]
View 

UDP glucuronosyltransferase 1A1 [Homo sapiens]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

EC:  2.4.-.-
Gene Ontology:  GO:0008194|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
28-524 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 881.75  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749    28 GKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDG--AFYTLKTYPVPFQREDVKESFVSLGHNVFENDSF 105
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGkpSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   106 lQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEAT- 184
Cdd:pfam00201  81 -GTVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   185 QCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDY 264
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   265 PRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 344
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   345 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 424
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   425 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 504
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 11118749   505 ITFKCCAYGYRKCLGKKGRV 524
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
28-524 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 881.75  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749    28 GKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDG--AFYTLKTYPVPFQREDVKESFVSLGHNVFENDSF 105
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGkpSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   106 lQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEAT- 184
Cdd:pfam00201  81 -GTVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   185 QCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDY 264
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   265 PRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 344
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   345 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 424
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   425 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 504
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 11118749   505 ITFKCCAYGYRKCLGKKGRV 524
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 29-446 1.38e-72

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 236.68  E-value: 1.38e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  29 KILLIPVDG-SHWLSMLGAIQQLQQRGHEIVVLAPDASLyirdgafytlktypvPFQREDVKESFVSLGHNVFENDSFLQ 107
Cdd:cd03784   2 RILFVPFPGqGHVNPMLPLAKALAARGHEVTVATPPFNF---------------ADLVEAAGLTFVPVGDDPDELELDSE 66

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 108 RVIKTYKKIKKDSAMLLSGCSHLlhnKELMASLAESS-FDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFeatqC 186
Cdd:cd03784  67 TNLGPDSLLELLRRLLKAADELL---DDLLAALRSSWkPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----Y 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 187 PNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYAtlaseflqrevtvqDLLSSASVWLFRSDFVKDYPR 266
Cdd:cd03784 140 LHPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLGLPPFSLVLL--------------LLRLVPPLYVIGPTFPSLPPD 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 267 PIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS--- 343
Cdd:cd03784 206 RPRLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgle 285

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 344 NLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL 423
Cdd:cd03784 286 RLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEEL 365

                       410       420
                ....*....|....*....|...
gi 11118749 424 ENALKAVINDKSYKENIMRLSSL 446
Cdd:cd03784 366 AKAVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 261-507 1.60e-42

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 158.97  E-value: 1.60e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  261 VKDYPRPIMPNMVFVGGI--NCLHQNPLSQEFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQT 332
Cdd:PHA03392 256 VFDNNRPVPPSVQYLGGLhlHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYN 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  333 VLWRYTGT-RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 411
Cdd:PHA03392 331 VLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  412 TLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsld 490
Cdd:PHA03392 411 ALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY---- 486

                        250
                 ....*....|....*..
gi 11118749  491 VIGFLLAVVLTVAFITF 507
Cdd:PHA03392 487 FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
263-444 1.63e-30

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 119.96  E-value: 1.63e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 263 DYPRP-IMPNMVFVGGInclhQNPLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGTR 341
Cdd:COG1819  86 EYPRPpDPANVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGLD 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 342 PSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM 418
Cdd:COG1819 161 PAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRRL 238

                       170       180
                ....*....|....*....|....*.
gi 11118749 419 TSEDLENALKAVINDKSYKENIMRLS 444
Cdd:COG1819 239 TAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 44-443 2.73e-19

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 89.74  E-value: 2.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749    44 LGAIQQLQQRGHEIVVLAPD--ASLYIRDGAfyTLKTYPVPFQREDVKEsfvslgHNVFEndSFLQRVIKTYKkikkDSA 121
Cdd:TIGR01426  13 LGVVEELVARGHRVTYATTEefAERVEAAGA--EFVLYGSALPPPDNPP------ENTEE--EPIDIIEKLLD----EAE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   122 MLLsgcshllhnKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPtvfFLHALPCSLEFEATQCPNPfsyvprPLSSHS 201
Cdd:TIGR01426  79 DVL---------PQLEEAYKGDRPDLIVYDIASWTGRLLARKWDVP---VISSFPTFAANEEFEEMVS------PAGEGS 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   202 dhmtfLQRVKNMLIAFSQnflcdvvyspYATLASEFLQRE----VTVQDLLSSasvwlfRSDFVKDY-PRPIMPN----- 271
Cdd:TIGR01426 141 -----AEEGAIAERGLAE----------YVARLSALLEEHgittPPVEFLAAP------RRDLNLVYtPKAFQPAgetfd 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   272 --MVFVGGinCLHQNPLSQEFeaYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN- 347
Cdd:TIGR01426 200 dsFTFVGP--CIGDRKEDGSW--ERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGEl 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   348 --NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 425
Cdd:TIGR01426 274 ppNVEVRQWVPQLEILKK--ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLRE 351

                         410
                  ....*....|....*...
gi 11118749   426 ALKAVINDKSYKENIMRL 443
Cdd:TIGR01426 352 AVLAVLSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
28-524 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 881.75  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749    28 GKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDG--AFYTLKTYPVPFQREDVKESFVSLGHNVFENDSF 105
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGkpSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   106 lQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEAT- 184
Cdd:pfam00201  81 -GTVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   185 QCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDY 264
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   265 PRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 344
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   345 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 424
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   425 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 504
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 11118749   505 ITFKCCAYGYRKCLGKKGRV 524
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 29-446 1.38e-72

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 236.68  E-value: 1.38e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  29 KILLIPVDG-SHWLSMLGAIQQLQQRGHEIVVLAPDASLyirdgafytlktypvPFQREDVKESFVSLGHNVFENDSFLQ 107
Cdd:cd03784   2 RILFVPFPGqGHVNPMLPLAKALAARGHEVTVATPPFNF---------------ADLVEAAGLTFVPVGDDPDELELDSE 66

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 108 RVIKTYKKIKKDSAMLLSGCSHLlhnKELMASLAESS-FDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFeatqC 186
Cdd:cd03784  67 TNLGPDSLLELLRRLLKAADELL---DDLLAALRSSWkPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----Y 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 187 PNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYAtlaseflqrevtvqDLLSSASVWLFRSDFVKDYPR 266
Cdd:cd03784 140 LHPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLGLPPFSLVLL--------------LLRLVPPLYVIGPTFPSLPPD 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 267 PIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS--- 343
Cdd:cd03784 206 RPRLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgle 285

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 344 NLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL 423
Cdd:cd03784 286 RLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEEL 365

                       410       420
                ....*....|....*....|...
gi 11118749 424 ENALKAVINDKSYKENIMRLSSL 446
Cdd:cd03784 366 AKAVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 261-507 1.60e-42

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 158.97  E-value: 1.60e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  261 VKDYPRPIMPNMVFVGGI--NCLHQNPLSQEFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQT 332
Cdd:PHA03392 256 VFDNNRPVPPSVQYLGGLhlHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYN 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  333 VLWRYTGT-RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 411
Cdd:PHA03392 331 VLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  412 TLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsld 490
Cdd:PHA03392 411 ALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY---- 486

                        250
                 ....*....|....*..
gi 11118749  491 VIGFLLAVVLTVAFITF 507
Cdd:PHA03392 487 FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
263-444 1.63e-30

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 119.96  E-value: 1.63e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 263 DYPRP-IMPNMVFVGGInclhQNPLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGTR 341
Cdd:COG1819  86 EYPRPpDPANVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGLD 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 342 PSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM 418
Cdd:COG1819 161 PAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRRL 238

                       170       180
                ....*....|....*....|....*.
gi 11118749 419 TSEDLENALKAVINDKSYKENIMRLS 444
Cdd:COG1819 239 TAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 44-443 2.73e-19

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 89.74  E-value: 2.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749    44 LGAIQQLQQRGHEIVVLAPD--ASLYIRDGAfyTLKTYPVPFQREDVKEsfvslgHNVFEndSFLQRVIKTYKkikkDSA 121
Cdd:TIGR01426  13 LGVVEELVARGHRVTYATTEefAERVEAAGA--EFVLYGSALPPPDNPP------ENTEE--EPIDIIEKLLD----EAE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   122 MLLsgcshllhnKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPtvfFLHALPCSLEFEATQCPNPfsyvprPLSSHS 201
Cdd:TIGR01426  79 DVL---------PQLEEAYKGDRPDLIVYDIASWTGRLLARKWDVP---VISSFPTFAANEEFEEMVS------PAGEGS 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   202 dhmtfLQRVKNMLIAFSQnflcdvvyspYATLASEFLQRE----VTVQDLLSSasvwlfRSDFVKDY-PRPIMPN----- 271
Cdd:TIGR01426 141 -----AEEGAIAERGLAE----------YVARLSALLEEHgittPPVEFLAAP------RRDLNLVYtPKAFQPAgetfd 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   272 --MVFVGGinCLHQNPLSQEFeaYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN- 347
Cdd:TIGR01426 200 dsFTFVGP--CIGDRKEDGSW--ERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGEl 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   348 --NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 425
Cdd:TIGR01426 274 ppNVEVRQWVPQLEILKK--ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLRE 351

                         410
                  ....*....|....*...
gi 11118749   426 ALKAVINDKSYKENIMRL 443
Cdd:TIGR01426 352 AVLAVLSDPRYAERLRKM 369
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 267-405 5.51e-13

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 70.84  E-value: 5.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  267 PIMP-NMVFVGGINCLHQNPLSQEfeaYINASGEHGIVVFSLGSM-VSEIPEkkAMAIADALGKIPQTVLWRytgTRPSN 344
Cdd:PLN02410 233 PIGPlHLVASAPTSLLEENKSCIE---WLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWV---IRPGS 304

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 11118749  345 LANNT-----------------ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 405
Cdd:PLN02410 305 VRGSEwieslpkefskiisgrgYIVKWAPQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 236-435 1.16e-12

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 70.08  E-value: 1.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  236 EFLQREVTVQDLLSSASVwlFRSDFVKDYPR-------PIMPNMVFVGGIN--CLHQNPLSQEFEAYINASGEHGIVVFS 306
Cdd:PLN02152 190 EFLKEESNPKILVNTFDS--LEPEFLTAIPNiemvavgPLLPAEIFTGSESgkDLSVRDQSSSYTLWLDSKTESSVIYVS 267

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  307 LGSMVsEIPEKKAMAIADAL--GKIP-------------------QTVLWRYTGTRpSNLANNTILVKWLPQNDLLGHPM 365
Cdd:PLN02152 268 FGTMV-ELSKKQIEELARALieGKRPflwvitdklnreakiegeeETEIEKIAGFR-HELEEVGMIVSWCSQIEVLRHRA 345

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 11118749  366 TRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME---TKGAGVTLNVLEMTSE-DLENALKAVINDKS 435
Cdd:PLN02152 346 VGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKLLEeiwKTGVRVRENSEGLVERgEIRRCLEAVMEEKS 419
PLN02210 PLN02210
UDP-glucosyl transferase
 293-430 1.95e-09

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 59.66  E-value: 1.95e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  293 YINASGEHGIVVFSLGSMVSEIpEKKAMAIADALGKIPQTVLWRytgTRPSNLANNT------------ILVKWLPQNDL 360
Cdd:PLN02210 262 WLDKQARSSVVYISFGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVVLEWSPQEKI 337

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 11118749  361 LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVL----EMTSEDLENALKAV 430
Cdd:PLN02210 338 LSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGVRMRNDavdgELKVEEVERCIEAV 412
PLN03015 PLN03015
UDP-glucosyl transferase
 282-421 4.04e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 58.94  E-value: 4.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  282 HQNPLSQEFEaYINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLW------RYTG-----------TRPSN 344
Cdd:PLN03015 250 HVEKRNSIFE-WLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpaSYLGasssdddqvsaSLPEG 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  345 LANNT-----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKrMETKGAGVTLNVLEMT 419
Cdd:PLN03015 328 FLDRTrgvglVVTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNAT-LLTEEIGVAVRTSELP 406


                 ..
gi 11118749  420 SE 421
Cdd:PLN03015 407 SE 408
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 293-446 5.05e-09

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 58.50  E-value: 5.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  293 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIpqTVLWRYTGTRPSNL---------ANNTILVKWLPQNDLLGH 363
Cdd:PLN02173 257 WLDKRPQGSVVYIAFGSM-AKLSSEQMEEIASAISNF--SYLWVVRASEESKLppgfletvdKDKSLVLKWSPQLQVLSN 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  364 PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME-TKGAGVTLNVLEMTS----EDLENALKAVIN---DKS 435
Cdd:PLN02173 334 KAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWKVGVRVKAEKESGiakrEEIEFSIKEVMEgekSKE 413

                        170
                 ....*....|.
gi 11118749  436 YKENIMRLSSL 446
Cdd:PLN02173 414 MKENAGKWRDL 424
PLN02555 PLN02555
limonoid glucosyltransferase
 351-442 6.66e-09

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 58.27  E-value: 6.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  351 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL------NVLEMTSEDL 423
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYLvDVFKTGVRLcrgeaeNKLITREEVA 420

                         90       100
                 ....*....|....*....|.
gi 11118749  424 ENALKAVINDKS--YKENIMR 442
Cdd:PLN02555 421 ECLLEATVGEKAaeLKQNALK 441
PLN00164 PLN00164
glucosyltransferase; Provisional
 353-401 1.48e-08

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 56.99  E-value: 1.48e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 11118749  353 KWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 401
Cdd:PLN00164 345 TWAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02534 PLN02534
UDP-glycosyltransferase
 350-415 1.73e-08

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 56.79  E-value: 1.73e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 11118749  350 ILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNV 415
Cdd:PLN02534 346 LLIKgWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 354-401 2.47e-08

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 56.53  E-value: 2.47e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 11118749  354 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 401
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN03004 PLN03004
UDP-glycosyltransferase
 293-445 6.41e-08

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 55.08  E-value: 6.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  293 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLWryTGTRPSNLANNTILVK------------------- 353
Cdd:PLN03004 263 WLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPELEKTELDLKsllpegflsrtedkgmvvk 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  354 -WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLE---MTSEDLENALK 428
Cdd:PLN03004 340 sWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMIvDEIKIAISMNESEtgfVSSTEVEKRVQ 419

                        170
                 ....*....|....*..
gi 11118749  429 AVINDKSYKENIMRLSS 445
Cdd:PLN03004 420 EIIGECPVRERTMAMKN 436
PLN02562 PLN02562
UDP-glycosyltransferase
 302-443 2.38e-07

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 53.35  E-value: 2.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  302 IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYT-----GTRPS---NLANNTILVKWLPQNDLLGHPMTRAFITHA 373
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNpvwreGLPPGyveRVSKQGKVVSWAPQLEVLKHQAVGCYLTHC 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 11118749  374 GSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNvlEMTSEDLENALKAVINDKSYKENIMRL 443
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEEGLRKVMEDSGMGERLMKL 423
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 267-402 3.36e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 52.70  E-value: 3.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  267 PIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW---RYTGTRPS 343
Cdd:PLN02448 241 PSIPYMELKDNSSSSNNEDNEPDYFQWLDSQPEGSVLYVSLGSFLS-VSSAQMDEIAAGLRDSGVRFLWvarGEASRLKE 319

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 11118749  344 NLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 402
Cdd:PLN02448 320 ICGDMGLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSK 378
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 262-404 5.15e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 52.11  E-value: 5.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  262 KDYPrPIMPnmvfVGGINCLHQNP-----LSQ--EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVL 334
Cdd:PLN02167 240 ENYP-PVYP----VGPILSLKDRTspnldSSDrdRIMRWLDDQPESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFL 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  335 W--RYTGTR--------PSNLANNT----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDN 400
Cdd:PLN02167 314 WsiRTNPAEyaspyeplPEGFMDRVmgrgLVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLN 393


                 ....
gi 11118749  401 AKRM 404
Cdd:PLN02167 394 AFTM 397
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 351-444 7.70e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 51.71  E-value: 7.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  351 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL-----------NVLEM 418
Cdd:PLN02554 346 VIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMvEELGLAVEIrkywrgdllagEMETV 425

                         90       100
                 ....*....|....*....|....*..
gi 11118749  419 TSEDLENALKAVI-NDKSYKENIMRLS 444
Cdd:PLN02554 426 TAEEIERGIRCLMeQDSDVRKRVKEMS 452
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 350-401 5.73e-06

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 48.71  E-value: 5.73e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 11118749  350 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 401
Cdd:PLN02863 346 VIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02207 PLN02207
UDP-glycosyltransferase
 289-404 6.22e-06

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 48.88  E-value: 6.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  289 EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLWRYTGTRPSN-----------LANNTILVKWLPQ 357
Cdd:PLN02207 264 ELMKWLDDQPEASVVFLCFGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEVTNddllpegfldrVSGRGMICGWSPQ 342

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 11118749  358 NDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 404
Cdd:PLN02207 343 VEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLM 389
PLN02208 PLN02208
glycosyltransferase family protein
 354-435 1.57e-05

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 47.32  E-value: 1.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  354 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALK 428
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 11118749  429 AVINDKS 435
Cdd:PLN02208 397 SVMDKDS 403
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 302-446 2.09e-05

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 47.16  E-value: 2.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  302 IVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW--RYTGTRPSN------------LANNTILVKWLPQNDLLGHPMTR 367
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  368 AFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLEM--------TSEDLENALKAVINDKSYKE 438
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 11118749  439 NIMRLSSL 446
Cdd:PLN03007 446 RRLRAKKL 453
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 370-450 3.81e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 44.24  E-value: 3.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749   370 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSS 445
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 11118749   446 LHKDR 450
Cdd:pfam04101 156 ASGFK 160
PLN00414 PLN00414
glycosyltransferase family protein
 301-465 5.81e-05

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 45.78  E-value: 5.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  301 GIVVFSLGSMVSEIPEKKAMAIADALgkiPQTVLWRYTGtrpsnlaNNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYE 380
Cdd:PLN00414 276 GMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVKG-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWE 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  381 SICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALKAVINDKSYKENIMRLSSLH-KDRPVEP 454
Cdd:PLN00414 346 SLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRedsgwFSKESLRDTVKSVMDKDSEIGNLVKRNHKKlKETLVSP 424

                        170
                 ....*....|.
gi 11118749  455 LDLAVFWVEFV 465
Cdd:PLN00414 425 GLLSGYADKFV 435
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 370-444 8.41e-05

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 44.90  E-value: 8.41e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 370 ITHAGSHGVYESICNGVPMVMMPLF----GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 441
Cdd:cd03785 257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                ...
gi 11118749 442 RLS 444
Cdd:cd03785 337 KLA 339
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 370-444 1.85e-04

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 43.96  E-value: 1.85e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 370 ITHAGSHGVYESICNGVPMVMMPL-F---GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 441
Cdd:COG0707 263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                ...
gi 11118749 442 RLS 444
Cdd:COG0707 343 ALA 345
PLN02764 PLN02764
glycosyltransferase family protein
 354-442 2.63e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 43.51  E-value: 2.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749  354 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKgAGVTLNVLE-----MTSEDLENALK 428
Cdd:PLN02764 324 WVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAIN 402

                         90
                 ....*....|....
gi 11118749  429 AVINDKSYKENIMR 442
Cdd:PLN02764 403 SVMKRDSEIGNLVK 416
PLN02670 PLN02670
transferase, transferring glycosyl groups
 350-411 3.19e-04

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 43.35  E-value: 3.19e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 11118749  350 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 411
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 370-442 1.43e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 40.88  E-value: 1.43e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 11118749  370 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 442
Cdd:PRK00726 257 ICRAGASTVAELAAAGLPAILVPLphaaDDHQTANARALVDAGAALLIPQSDLTPEKLAEKLLELLSDPERLEAMAE 333
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 358-443 1.62e-03

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 40.76  E-value: 1.62e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11118749 358 NDLLGhpMTRAFITHAGSHGVYESICNGVPMVM-MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSY 436
Cdd:cd17507 262 NELMA--ASDLVITKPGGLTISEALARGLPVIIyDPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMM 339


                ....*..
gi 11118749 437 KENIMRL 443
Cdd:cd17507 340 SEAAKEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH