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Conserved domains on  [gi|11072030|gb|AAG28909|]
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F12A21.9 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-4CXXC_R1 pfam10497
Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor ...
 27-126 9.55e-60

Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.


:

Pssm-ID: 463117  Cd Length: 99  Bit Score: 192.09  E-value: 9.55e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11072030    27 YDSSNGKTCHQCRQKTMDFVASCKAmkkdKQCT---INFCHKCLINRYGENAEEVAKLDDWICPQCRGICNCSFCRKKRG 103
Cdd:pfam10497   1 YDSVNGKTCHQCRQKTLDTKTSCRN----SQCKgvrGQFCGDCLRNRYGENVEEALANPDWICPKCRGICNCSFCRKKKG 76

                          90       100
                  ....*....|....*....|...
gi 11072030   104 LNPTGILAHKAKASGLASVSMLL 126
Cdd:pfam10497  77 LAPTGILYHKAKALGFSSVAHYL 99
DDT smart00571
domain in different transcription and chromosome remodeling factors;
216-282 2.81e-12

domain in different transcription and chromosome remodeling factors;


:

Pssm-ID: 214726  Cd Length: 63  Bit Score: 61.88  E-value: 2.81e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 11072030    216 TEEAGNVFQLFEFCSAFGKALELKEGQAetvVRELFSCGRNTrRQQYCSIIQLMIQLLDLISKDREM 282
Cdd:smart00571   1 NEAFGDLLMVYEFLRSFGKVLGLSPFRA---TLEDFIAALKC-RDQNGLLTEVHVVLLRAILKDEGE 63
 
Name Accession Description Interval E-value
zf-4CXXC_R1 pfam10497
Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor ...
 27-126 9.55e-60

Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.


Pssm-ID: 463117  Cd Length: 99  Bit Score: 192.09  E-value: 9.55e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11072030    27 YDSSNGKTCHQCRQKTMDFVASCKAmkkdKQCT---INFCHKCLINRYGENAEEVAKLDDWICPQCRGICNCSFCRKKRG 103
Cdd:pfam10497   1 YDSVNGKTCHQCRQKTLDTKTSCRN----SQCKgvrGQFCGDCLRNRYGENVEEALANPDWICPKCRGICNCSFCRKKKG 76

                          90       100
                  ....*....|....*....|...
gi 11072030   104 LNPTGILAHKAKASGLASVSMLL 126
Cdd:pfam10497  77 LAPTGILYHKAKALGFSSVAHYL 99
DDT smart00571
domain in different transcription and chromosome remodeling factors;
216-282 2.81e-12

domain in different transcription and chromosome remodeling factors;


Pssm-ID: 214726  Cd Length: 63  Bit Score: 61.88  E-value: 2.81e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 11072030    216 TEEAGNVFQLFEFCSAFGKALELKEGQAetvVRELFSCGRNTrRQQYCSIIQLMIQLLDLISKDREM 282
Cdd:smart00571   1 NEAFGDLLMVYEFLRSFGKVLGLSPFRA---TLEDFIAALKC-RDQNGLLTEVHVVLLRAILKDEGE 63
RING-HC_RNF39 cd16592
RING finger, HC subclass, found in RING finger protein 39 (RNF39) and similar proteins; RNF39, ...
 58-93 3.02e-04

RING finger, HC subclass, found in RING finger protein 39 (RNF39) and similar proteins; RNF39, also called protein HZFw, may play a role in prolonged long term-potentiation (LTP) maintenance. It is involved in the etiology of Behcet's disease (BD). It may also be involved in HIV-1 replication. RNF39 acts as an E3 ubiquitin ligase that inhibits retinoic acid-inducible gene-I (RIG-I)-like receptor (RLR) pathways by mediating K48-linked ubiquitination and proteasomal degradation of DDX3X (DEAD-box RNA helicase 3, X-linked). RNF39 contains a typical C3HC4-type RING-HC finger.


Pssm-ID: 438254 [Multi-domain]  Cd Length: 58  Bit Score: 38.97  E-value: 3.02e-04
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 11072030  58 CTINFCHKCLINRYGENAEEVAKLDDWICPQCRGIC 93
Cdd:cd16592  22 CEHSFCRACIARHWGQEAMEGNGAEGVFCPQCGEPC 57
 
Name Accession Description Interval E-value
zf-4CXXC_R1 pfam10497
Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor ...
 27-126 9.55e-60

Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.


Pssm-ID: 463117  Cd Length: 99  Bit Score: 192.09  E-value: 9.55e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11072030    27 YDSSNGKTCHQCRQKTMDFVASCKAmkkdKQCT---INFCHKCLINRYGENAEEVAKLDDWICPQCRGICNCSFCRKKRG 103
Cdd:pfam10497   1 YDSVNGKTCHQCRQKTLDTKTSCRN----SQCKgvrGQFCGDCLRNRYGENVEEALANPDWICPKCRGICNCSFCRKKKG 76

                          90       100
                  ....*....|....*....|...
gi 11072030   104 LNPTGILAHKAKASGLASVSMLL 126
Cdd:pfam10497  77 LAPTGILYHKAKALGFSSVAHYL 99
DDT smart00571
domain in different transcription and chromosome remodeling factors;
216-282 2.81e-12

domain in different transcription and chromosome remodeling factors;


Pssm-ID: 214726  Cd Length: 63  Bit Score: 61.88  E-value: 2.81e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 11072030    216 TEEAGNVFQLFEFCSAFGKALELKEGQAetvVRELFSCGRNTrRQQYCSIIQLMIQLLDLISKDREM 282
Cdd:smart00571   1 NEAFGDLLMVYEFLRSFGKVLGLSPFRA---TLEDFIAALKC-RDQNGLLTEVHVVLLRAILKDEGE 63
RING-HC_RNF39 cd16592
RING finger, HC subclass, found in RING finger protein 39 (RNF39) and similar proteins; RNF39, ...
 58-93 3.02e-04

RING finger, HC subclass, found in RING finger protein 39 (RNF39) and similar proteins; RNF39, also called protein HZFw, may play a role in prolonged long term-potentiation (LTP) maintenance. It is involved in the etiology of Behcet's disease (BD). It may also be involved in HIV-1 replication. RNF39 acts as an E3 ubiquitin ligase that inhibits retinoic acid-inducible gene-I (RIG-I)-like receptor (RLR) pathways by mediating K48-linked ubiquitination and proteasomal degradation of DDX3X (DEAD-box RNA helicase 3, X-linked). RNF39 contains a typical C3HC4-type RING-HC finger.


Pssm-ID: 438254 [Multi-domain]  Cd Length: 58  Bit Score: 38.97  E-value: 3.02e-04
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 11072030  58 CTINFCHKCLINRYGENAEEVAKLDDWICPQCRGIC 93
Cdd:cd16592  22 CEHSFCRACIARHWGQEAMEGNGAEGVFCPQCGEPC 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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