|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
732-1057 |
2.90e-80 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
:
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 264.99 E-value: 2.90e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 732 LTRYLKRLKLGTLRAGRLLELLHCaheTQEPGIWKHVSHQlpGHLSFLGTRLTAP--DVYVLGRALETASqdfslDLRQT 809
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 810 GIEPSRLGDLVGLSCVTSFRASLS-DTMALWESLQH---QGETQLLQAAEEKfTIEPFKAKSPKDV-EDLDSLVQTQRLR 884
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 885 N--PSADAAKDLPAIRDLKKLEFALGPvLGPQAFPTLAKILPAFSSLQHLDLDSlseNKIGDKGVSKLSATFPQLKALET 962
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANNG-IGDAGIRALAEGLKANCNLEVLDLNN---NGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 963 LNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLqKC 1042
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-LE 304
|
330
....*....|....*
gi 9931452 1043 PQVETLAMWTPTIPF 1057
Cdd:cd00116 305 PGNELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
360-531 |
1.91e-50 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
:
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 175.57 E-value: 1.91e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 360 QVVAVLGKAGQGKSHWARTVSHIWAQGQLPQY-DFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMNDEVIDHIVRQPD 438
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 439 RVLLILDAFEELEAQDSLLHGpcgplspePCSLRGLLAGLFQRKLLRGCTLLLTARPRGR--LAQSLSKADaIFEVPSFS 516
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDG--------PCPVLTLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 9931452 517 TKQAQIYMRHYFENS 531
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 super family |
cl39284 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
656-761 |
1.08e-05 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
The actual alignment was detected with superfamily member pfam17776:
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 45.75 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 656 LQCFLGAVWLAQCnEMKDKELPQYLALTPRKKRPYDNWLEGVP-----------RFLAGLVFQPRAHCLGALVEPAmaaV 724
Cdd:pfam17776 4 FQEFFAALFYVLS-FKEEKSNPLKEFFGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCK---L 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 9931452 725 ADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQE 761
Cdd:pfam17776 80 SSEIKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
732-1057 |
2.90e-80 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 264.99 E-value: 2.90e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 732 LTRYLKRLKLGTLRAGRLLELLHCaheTQEPGIWKHVSHQlpGHLSFLGTRLTAP--DVYVLGRALETASqdfslDLRQT 809
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 810 GIEPSRLGDLVGLSCVTSFRASLS-DTMALWESLQH---QGETQLLQAAEEKfTIEPFKAKSPKDV-EDLDSLVQTQRLR 884
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 885 N--PSADAAKDLPAIRDLKKLEFALGPvLGPQAFPTLAKILPAFSSLQHLDLDSlseNKIGDKGVSKLSATFPQLKALET 962
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANNG-IGDAGIRALAEGLKANCNLEVLDLNN---NGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 963 LNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLqKC 1042
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-LE 304
|
330
....*....|....*
gi 9931452 1043 PQVETLAMWTPTIPF 1057
Cdd:cd00116 305 PGNELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
360-531 |
1.91e-50 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 175.57 E-value: 1.91e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 360 QVVAVLGKAGQGKSHWARTVSHIWAQGQLPQY-DFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMNDEVIDHIVRQPD 438
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 439 RVLLILDAFEELEAQDSLLHGpcgplspePCSLRGLLAGLFQRKLLRGCTLLLTARPRGR--LAQSLSKADaIFEVPSFS 516
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDG--------PCPVLTLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 9931452 517 TKQAQIYMRHYFENS 531
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
919-1070 |
1.22e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 86.77 E-value: 1.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 919 LAKILPAFSSLQHLDLdslSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALaKSLLRLSLYNNC 998
Cdd:COG5238 284 LAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQEN-TTLHSLDLSDNQ 359
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 9931452 999 ICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKcPQVETLAMWTPTIPFGVQEHLQQLDARI 1070
Cdd:COG5238 360 IGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT-NRLHTLILDGNLIGAEAQQRLEQLLERI 430
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
656-761 |
1.08e-05 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 45.75 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 656 LQCFLGAVWLAQCnEMKDKELPQYLALTPRKKRPYDNWLEGVP-----------RFLAGLVFQPRAHCLGALVEPAmaaV 724
Cdd:pfam17776 4 FQEFFAALFYVLS-FKEEKSNPLKEFFGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCK---L 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 9931452 725 ADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQE 761
Cdd:pfam17776 80 SSEIKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
987-1013 |
1.99e-04 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 39.31 E-value: 1.99e-04
10 20
....*....|....*....|....*..
gi 9931452 987 KSLLRLSLYNNCICDEGAKSLARVLPD 1013
Cdd:smart00368 2 PSLRELDLSNNKLGDEGARALAEALKD 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
732-1057 |
2.90e-80 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 264.99 E-value: 2.90e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 732 LTRYLKRLKLGTLRAGRLLELLHCaheTQEPGIWKHVSHQlpGHLSFLGTRLTAP--DVYVLGRALETASqdfslDLRQT 809
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 810 GIEPSRLGDLVGLSCVTSFRASLS-DTMALWESLQH---QGETQLLQAAEEKfTIEPFKAKSPKDV-EDLDSLVQTQRLR 884
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 885 N--PSADAAKDLPAIRDLKKLEFALGPvLGPQAFPTLAKILPAFSSLQHLDLDSlseNKIGDKGVSKLSATFPQLKALET 962
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANNG-IGDAGIRALAEGLKANCNLEVLDLNN---NGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 963 LNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLqKC 1042
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-LE 304
|
330
....*....|....*
gi 9931452 1043 PQVETLAMWTPTIPF 1057
Cdd:cd00116 305 PGNELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
360-531 |
1.91e-50 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 175.57 E-value: 1.91e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 360 QVVAVLGKAGQGKSHWARTVSHIWAQGQLPQY-DFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMNDEVIDHIVRQPD 438
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 439 RVLLILDAFEELEAQDSLLHGpcgplspePCSLRGLLAGLFQRKLLRGCTLLLTARPRGR--LAQSLSKADaIFEVPSFS 516
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDG--------PCPVLTLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 9931452 517 TKQAQIYMRHYFENS 531
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
919-1070 |
1.22e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 86.77 E-value: 1.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 919 LAKILPAFSSLQHLDLdslSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALaKSLLRLSLYNNC 998
Cdd:COG5238 284 LAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQEN-TTLHSLDLSDNQ 359
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 9931452 999 ICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKcPQVETLAMWTPTIPFGVQEHLQQLDARI 1070
Cdd:COG5238 360 IGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT-NRLHTLILDGNLIGAEAQQRLEQLLERI 430
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
911-1048 |
9.79e-15 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 77.91 E-value: 9.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 911 LGPQAFPTLAKILPAFSSLQHLDLdslSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALpALAKSLL 990
Cdd:COG5238 248 IGDEGVIALAEALKNNTTVETLYL---SGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGL-QGNKTLH 323
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 9931452 991 RLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETL 1048
Cdd:COG5238 324 TLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLREL 381
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
930-1065 |
1.75e-13 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 74.06 E-value: 1.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 930 QHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALpALAKSLLRLSLYNNCICDEGAKSLAR 1009
Cdd:COG5238 180 NSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEAL-KGNKSLTTLDLSNNQIGDEGVIALAE 258
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 1010 VLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPF----GVQEHLQQ 1065
Cdd:COG5238 259 ALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDegaiALAEGLQG 318
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
918-1048 |
1.96e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 64.18 E-value: 1.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 918 TLAKILPAFSSLQHLDldsLSENKIGDkgvskLSATFPQLKALETLNLSQNSITDvgackLAEALPALaKSLLRLSLYNN 997
Cdd:COG4886 127 DLPEELANLTNLKELD---LSNNQLTD-----LPEPLGNLTNLKSLDLSNNQLTD-----LPEELGNL-TNLKELDLSNN 192
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 9931452 998 CIcdegaKSLARVLPDMVSLRVMDVQFNKFTAvgaqqLTSSLQKCPQVETL 1048
Cdd:COG4886 193 QI-----TDLPEPLGNLTNLEELDLSGNQLTD-----LPEPLANLTNLETL 233
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
923-1048 |
3.92e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.95 E-value: 3.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 923 LPAFSSLQHLDLdslSENKIGDkgvskLSATFPQLKALETLNLSQNSITDvgackLAEALPALaKSLLRLSLYNNCIcde 1002
Cdd:COG4886 109 LSNLTNLESLDL---SGNQLTD-----LPEELANLTNLKELDLSNNQLTD-----LPEPLGNL-TNLKSLDLSNNQL--- 171
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 9931452 1003 gaKSLARVLPDMVSLRVMDVQFNKFTAvgaqqLTSSLQKCPQVETL 1048
Cdd:COG4886 172 --TDLPEELGNLTNLKELDLSNNQITD-----LPEPLGNLTNLEEL 210
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
358-938 |
4.48e-08 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 57.51 E-value: 4.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 358 ETQVVAVLGKAGQGKSHWAR-TVSHIWAQGQLPQYDFVFYVPCQCLDRPGDtyhLRDLLCPPNLQPLAMNDEVIDHIVRQ 436
Cdd:COG5635 179 KKKRLLILGEPGSGKTTLLRyLALELAERYLDAEDPIPILIELRDLAEEAS---LEDLLAEALEKRGGEPEDALERLLRN 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 437 pDRVLLILDAFEELEAQDSLLHgpcgplspepcsLRGLLAGLFQRklLRGCTLLLTARPRGRLAQSLSKADaIFEVPSFS 516
Cdd:COG5635 256 -GRLLLLLDGLDEVPDEADRDE------------VLNQLRRFLER--YPKARVIITSRPEGYDSSELEGFE-VLELAPLS 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 517 TKQAQIYMRHYFENSGTAGshDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKalldqgAGAQLPCTLTGLY--------- 587
Cdd:COG5635 320 DEQIEEFLKKWFEATERKA--ERLLEALEENPELRELARNPLLLTLLALLLR------ERGELPDTRAELYeqfvellle 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 588 ----VGLLGPAAQNSPPGALVELAKLAWELgrrHQStlQETQFPSVEVKTWAVAQGLMQQTTEA---QLAFSSFLLQC-- 658
Cdd:COG5635 392 rwdeQRGLTIYRELSREELRELLSELALAM---QEN--GRTEFAREELEEILREYLGRRKDAEAlldELLLRTGLLVErg 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 659 -------------FLGAVWLAqcnemkdkELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHC--LGALVEPAMAA 723
Cdd:COG5635 467 egrysfahrsfqeYLAARALV--------EELDEELLELLAEHLEDPRWREVLLLLAGLLDDVKQIKelIDALLARDDAA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 724 VADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLP---GHLSFLGTRLTAPDVYVLGRALETASQ 800
Cdd:COG5635 539 ALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLLLLLLALllaLLALDLGLAALLLLLLLLLLLLLLLAL 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 801 DFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQT 880
Cdd:COG5635 619 ALLLALLLLLLLLLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLLLLLLAELLLALLALASLLLLLLLA 698
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 9931452 881 QRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLS 938
Cdd:COG5635 699 LALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESS 756
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
918-1040 |
2.49e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 54.55 E-value: 2.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 918 TLAKILPAFSSLQHLDLdslSENKIGDkgvskLSATFPQLKALETLNLSQNSITDvgacklaeaLPALA--KSLLRLSLY 995
Cdd:COG4886 196 DLPEPLGNLTNLEELDL---SGNQLTD-----LPEPLANLTNLETLDLSNNQLTD---------LPELGnlTNLEELDLS 258
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 9931452 996 NNCICDegakslarvLPD---MVSLRVMDVQFNKFTAVGAQQLTSSLQ 1040
Cdd:COG4886 259 NNQLTD---------LPPlanLTNLKTLDLSNNQLTDLKLKELELLLG 297
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
656-761 |
1.08e-05 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 45.75 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9931452 656 LQCFLGAVWLAQCnEMKDKELPQYLALTPRKKRPYDNWLEGVP-----------RFLAGLVFQPRAHCLGALVEPAmaaV 724
Cdd:pfam17776 4 FQEFFAALFYVLS-FKEEKSNPLKEFFGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCK---L 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 9931452 725 ADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQE 761
Cdd:pfam17776 80 SSEIKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
987-1013 |
1.99e-04 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 39.31 E-value: 1.99e-04
10 20
....*....|....*....|....*..
gi 9931452 987 KSLLRLSLYNNCICDEGAKSLARVLPD 1013
Cdd:smart00368 2 PSLRELDLSNNKLGDEGARALAEALKD 28
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
928-1000 |
1.44e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 41.31 E-value: 1.44e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 9931452 928 SLQHLDLdslSENKIGDkgVSKLSAtfpqLKALETLNLSQNSITDVGAckLAEALPALaKSLLRLSLYNNCIC 1000
Cdd:cd21340 121 SLRVLNI---SGNNIDS--LEPLAP----LRNLEQLDASNNQISDLEE--LLDLLSSW-PSLRELDLTGNPVC 181
|
|
| |
