NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|6730699|gb|AAF27094|]
View 

Putative isochorismate synthase [Arabidopsis thaliana]

Protein Classification

PLN02786 family protein( domain architecture ID 11477140)

PLN02786 family protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PLN02786 PLN02786
isochorismate synthase
 1-512 0e+00

isochorismate synthase


:

Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 1005.46  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699     1 MNGCEADHKAPLGTVETRTLSTVPSPAAATERLITAVSDLKSQPPPFSSGIVRLQVPIEQKIGAIDWLHAQNEILPRSFF 80
Cdd:PLN02786  20 MNGCQGDPKVPVGTVETRTLPAVLSPADATERLISAVSELKSQPPPFSSGILRLQVPIPQQIGAIDWLHAQNELLPRCFF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    81 SRRSDSG-RPDLLQDFSSDNGS-SDHNPVSVAGIGSAVFFRDLDPFSHDDWRSIRRFLSSKSPLIRAYGGLRFDPTGKIA 158
Cdd:PLN02786 100 SRRSDTGdRPDLLLDSSNGNGNgSDHNLVSVAGVGSAVFFRDLDPFSHDDWRSIKRFLSSKSPLIRAYGAIRFDPNGKIS 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   159 VEWEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELSWTLENAIEALQETMLQVSSVIMRLRRESLGVIVVSKNHVPSE 238
Cdd:PLN02786 180 VEWEPFGSFYFIVPQVEFNELGGSSMLAATIAWDDALSWTWENAIEALQETMLQVSSVVMKLRKESLGVSVLSKNHVPSK 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   239 GAYYPAVNNALEIIKDKHSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKH 318
Cdd:PLN02786 260 GAWHLAVNKALQIIKRKSSPLKKVVLARSSRIITDTDIDPIAWLACLQVEGQNAYQFCLQPPDAPAFIGNTPEQLFHRKG 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   319 LGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQHLYSQLAGQ 398
Cdd:PLN02786 340 LGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICDRVVVEPHKAIRKLARVQHLYAQLAGR 419

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   399 LKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSALVEKGLGALIYAGTGI 478
Cdd:PLN02786 420 LRSEDDEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGGGESEFAVGIRSALVEKGLGALIYAGTGI 499

                        490       500       510
                 ....*....|....*....|....*....|....
gi 6730699   479 VSGSNPSSEWNELELKISQFTKSLEHESALQPIN 512
Cdd:PLN02786 500 VEGSNPSSEWNELELKISQFTKSLEHESALSPQN 533
 
Name Accession Description Interval E-value
PLN02786 PLN02786
isochorismate synthase
 1-512 0e+00

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 1005.46  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699     1 MNGCEADHKAPLGTVETRTLSTVPSPAAATERLITAVSDLKSQPPPFSSGIVRLQVPIEQKIGAIDWLHAQNEILPRSFF 80
Cdd:PLN02786  20 MNGCQGDPKVPVGTVETRTLPAVLSPADATERLISAVSELKSQPPPFSSGILRLQVPIPQQIGAIDWLHAQNELLPRCFF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    81 SRRSDSG-RPDLLQDFSSDNGS-SDHNPVSVAGIGSAVFFRDLDPFSHDDWRSIRRFLSSKSPLIRAYGGLRFDPTGKIA 158
Cdd:PLN02786 100 SRRSDTGdRPDLLLDSSNGNGNgSDHNLVSVAGVGSAVFFRDLDPFSHDDWRSIKRFLSSKSPLIRAYGAIRFDPNGKIS 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   159 VEWEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELSWTLENAIEALQETMLQVSSVIMRLRRESLGVIVVSKNHVPSE 238
Cdd:PLN02786 180 VEWEPFGSFYFIVPQVEFNELGGSSMLAATIAWDDALSWTWENAIEALQETMLQVSSVVMKLRKESLGVSVLSKNHVPSK 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   239 GAYYPAVNNALEIIKDKHSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKH 318
Cdd:PLN02786 260 GAWHLAVNKALQIIKRKSSPLKKVVLARSSRIITDTDIDPIAWLACLQVEGQNAYQFCLQPPDAPAFIGNTPEQLFHRKG 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   319 LGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQHLYSQLAGQ 398
Cdd:PLN02786 340 LGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICDRVVVEPHKAIRKLARVQHLYAQLAGR 419

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   399 LKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSALVEKGLGALIYAGTGI 478
Cdd:PLN02786 420 LRSEDDEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGGGESEFAVGIRSALVEKGLGALIYAGTGI 499

                        490       500       510
                 ....*....|....*....|....*....|....
gi 6730699   479 VSGSNPSSEWNELELKISQFTKSLEHESALQPIN 512
Cdd:PLN02786 500 VEGSNPSSEWNELELKISQFTKSLEHESALSPQN 533
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 143-502 4.79e-143

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 415.23  E-value: 4.79e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    143 IRAYGGLRFDPTGKIAveWEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELswtleNAIEALQETMLQVSSVIMRLRR 222
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAA--WEEFGEGYFVLPEVLVESDGGGTLLTCTIVAEPEL-----NEADLLLYAKFAVSSGIRPLRA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    223 ESLGVIVVSKNHVPSEGAYYPAVNNALEIIKDkhSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGA 302
Cdd:TIGR00543  74 LPEQMTTLTTGEDPDKAAWRTAVEEALENIRQ--GPLDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEPPQG 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    303 PAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSV 382
Cdd:TIGR00543 152 GVFLGATPERLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPEL 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    383 RKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRS 461
Cdd:TIGR00543 232 LKLANVQHLYTPISARLKDGDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGeGNGEFAVGIRS 311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 6730699    462 ALVEKGLGALiYAGTGIVSGSNPSSEWNELELKISQFTKSL 502
Cdd:TIGR00543 312 ALVEDGQVRL-YAGAGIVADSDPESEWEETELKLQTMLRAL 351
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 101-496 1.45e-88

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 275.49  E-value: 1.45e-88
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  101 SSDHNPVSVAGIGSA--VFFRDLDPFSHDD--WRSIRRFLSSKSPLIRAYGGLRFDPTgkiavewEHFGSFYFTVPQVef 176
Cdd:COG1169   6 ASPDRGEGLAGLGEAarFEAPGPDRFAALAaaWQALLADAALAGTGPRAFGGFAFDPD-------SPAPAARLVLPRL-- 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  177 defggssmlaatvawdnelswtlenaiealqetmlqvssVIMRLRReslgvivvsknHVPSEGAYYPAVNNALEIIKDKH 256
Cdd:COG1169  77 ---------------------------------------LLRRSRR-----------GVPDPAEWREAVAQALEAIRAGE 106

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  257 spLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKHLGVCSEALAATRPRGDSK 336
Cdd:COG1169 107 --LDKVVLARALDLTLDEPIDPRALLARLRRRNPDCYTFAVELGAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADP 184

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  337 VREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTP 416
Cdd:COG1169 185 EEDAALAAALLASEKDRREHALVVDSIREALAPLCSSLDVPEEPELLRLRNVQHLATPITGTLDPGVSALDLAAALHPTP 264

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  417 AVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRSALVEKGLgALIYAGTGIVSGSNPSSEWNELELKI 495
Cdd:COG1169 265 AVGGTPREAALALIRELEPFDRGWYAGPVGWVDAdGDGEFAVAIRSALIDGNR-ARLFAGAGIVAGSDPEAEWAETEAKL 343


                .
gi 6730699  496 S 496
Cdd:COG1169 344 R 344
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 240-494 4.88e-72

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 229.36  E-value: 4.88e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    240 AYYPAVNNALEIIKDKHspLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGaPAFIGNTPERLFHRKHL 319
Cdd:pfam00425   2 DYLAAVEKAKEAIRAGD--LYKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYFRTGD-FTFLGASPERLLSVDGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    320 GVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTIC--DRVVVKPHKSVRKLARVQHLYSQLAG 397
Cdd:pfam00425  79 RIITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCvpGSVKVPELPEVERYGTVQHLVSTISG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    398 QLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRSALVEKGLgALIYAGT 476
Cdd:pfam00425 159 RLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPdGDADFAVAIRTALVDNGR-ARLYAGA 237

                         250
                  ....*....|....*...
gi 6730699    477 GIVSGSNPSSEWNELELK 494
Cdd:pfam00425 238 GIVADSDPEAEWEETEAK 255
 
Name Accession Description Interval E-value
PLN02786 PLN02786
isochorismate synthase
 1-512 0e+00

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 1005.46  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699     1 MNGCEADHKAPLGTVETRTLSTVPSPAAATERLITAVSDLKSQPPPFSSGIVRLQVPIEQKIGAIDWLHAQNEILPRSFF 80
Cdd:PLN02786  20 MNGCQGDPKVPVGTVETRTLPAVLSPADATERLISAVSELKSQPPPFSSGILRLQVPIPQQIGAIDWLHAQNELLPRCFF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    81 SRRSDSG-RPDLLQDFSSDNGS-SDHNPVSVAGIGSAVFFRDLDPFSHDDWRSIRRFLSSKSPLIRAYGGLRFDPTGKIA 158
Cdd:PLN02786 100 SRRSDTGdRPDLLLDSSNGNGNgSDHNLVSVAGVGSAVFFRDLDPFSHDDWRSIKRFLSSKSPLIRAYGAIRFDPNGKIS 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   159 VEWEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELSWTLENAIEALQETMLQVSSVIMRLRRESLGVIVVSKNHVPSE 238
Cdd:PLN02786 180 VEWEPFGSFYFIVPQVEFNELGGSSMLAATIAWDDALSWTWENAIEALQETMLQVSSVVMKLRKESLGVSVLSKNHVPSK 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   239 GAYYPAVNNALEIIKDKHSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKH 318
Cdd:PLN02786 260 GAWHLAVNKALQIIKRKSSPLKKVVLARSSRIITDTDIDPIAWLACLQVEGQNAYQFCLQPPDAPAFIGNTPEQLFHRKG 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   319 LGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQHLYSQLAGQ 398
Cdd:PLN02786 340 LGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICDRVVVEPHKAIRKLARVQHLYAQLAGR 419

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   399 LKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSALVEKGLGALIYAGTGI 478
Cdd:PLN02786 420 LRSEDDEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGGGESEFAVGIRSALVEKGLGALIYAGTGI 499

                        490       500       510
                 ....*....|....*....|....*....|....
gi 6730699   479 VSGSNPSSEWNELELKISQFTKSLEHESALQPIN 512
Cdd:PLN02786 500 VEGSNPSSEWNELELKISQFTKSLEHESALSPQN 533
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 143-502 4.79e-143

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 415.23  E-value: 4.79e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    143 IRAYGGLRFDPTGKIAveWEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELswtleNAIEALQETMLQVSSVIMRLRR 222
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAA--WEEFGEGYFVLPEVLVESDGGGTLLTCTIVAEPEL-----NEADLLLYAKFAVSSGIRPLRA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    223 ESLGVIVVSKNHVPSEGAYYPAVNNALEIIKDkhSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGA 302
Cdd:TIGR00543  74 LPEQMTTLTTGEDPDKAAWRTAVEEALENIRQ--GPLDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEPPQG 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    303 PAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSV 382
Cdd:TIGR00543 152 GVFLGATPERLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPEL 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    383 RKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRS 461
Cdd:TIGR00543 232 LKLANVQHLYTPISARLKDGDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGeGNGEFAVGIRS 311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 6730699    462 ALVEKGLGALiYAGTGIVSGSNPSSEWNELELKISQFTKSL 502
Cdd:TIGR00543 312 ALVEDGQVRL-YAGAGIVADSDPESEWEETELKLQTMLRAL 351
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 101-496 1.45e-88

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 275.49  E-value: 1.45e-88
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  101 SSDHNPVSVAGIGSA--VFFRDLDPFSHDD--WRSIRRFLSSKSPLIRAYGGLRFDPTgkiavewEHFGSFYFTVPQVef 176
Cdd:COG1169   6 ASPDRGEGLAGLGEAarFEAPGPDRFAALAaaWQALLADAALAGTGPRAFGGFAFDPD-------SPAPAARLVLPRL-- 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  177 defggssmlaatvawdnelswtlenaiealqetmlqvssVIMRLRReslgvivvsknHVPSEGAYYPAVNNALEIIKDKH 256
Cdd:COG1169  77 ---------------------------------------LLRRSRR-----------GVPDPAEWREAVAQALEAIRAGE 106

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  257 spLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKHLGVCSEALAATRPRGDSK 336
Cdd:COG1169 107 --LDKVVLARALDLTLDEPIDPRALLARLRRRNPDCYTFAVELGAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADP 184

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  337 VREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTP 416
Cdd:COG1169 185 EEDAALAAALLASEKDRREHALVVDSIREALAPLCSSLDVPEEPELLRLRNVQHLATPITGTLDPGVSALDLAAALHPTP 264

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  417 AVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRSALVEKGLgALIYAGTGIVSGSNPSSEWNELELKI 495
Cdd:COG1169 265 AVGGTPREAALALIRELEPFDRGWYAGPVGWVDAdGDGEFAVAIRSALIDGNR-ARLFAGAGIVAGSDPEAEWAETEAKL 343


                .
gi 6730699  496 S 496
Cdd:COG1169 344 R 344
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 240-494 4.88e-72

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 229.36  E-value: 4.88e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    240 AYYPAVNNALEIIKDKHspLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGaPAFIGNTPERLFHRKHL 319
Cdd:pfam00425   2 DYLAAVEKAKEAIRAGD--LYKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYFRTGD-FTFLGASPERLLSVDGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    320 GVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTIC--DRVVVKPHKSVRKLARVQHLYSQLAG 397
Cdd:pfam00425  79 RIITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCvpGSVKVPELPEVERYGTVQHLVSTISG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    398 QLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRSALVEKGLgALIYAGT 476
Cdd:pfam00425 159 RLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPdGDADFAVAIRTALVDNGR-ARLYAGA 237

                         250
                  ....*....|....*...
gi 6730699    477 GIVSGSNPSSEWNELELK 494
Cdd:pfam00425 238 GIVADSDPEAEWEETEAK 255
PRK07054 PRK07054
isochorismate synthase;
144-503 5.66e-51

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 180.73  E-value: 5.66e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   144 RAYGGLRFDPTGKIAVEWEHFGSFYFTVPQVEFDEFGGS-----SMLAATVAWDNELSWTLENAIEALQETMLQVSSVIM 218
Cdd:PRK07054 105 RLVGGFRFDPRGPRSAHWQAFADASLTLAKLLVVREGEAywavcQHLVAAHDDPAALAGACCARIERLARPAPAADDDAP 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   219 RLRREslgvivvsknHVPSEGAYYPAVNNALEIIKDkhSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQ 298
Cdd:PRK07054 185 RLLRA----------SALQAREWQHEVRRAVDAIRG--GAFGKVVLARDVLQQYARPVAIGPLLRRLRLRDPHAHLFAFR 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   299 PPGApAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKP 378
Cdd:PRK07054 253 RGNA-CFLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMASAKDRLEHALVVDAIRAALAPLSRALDIPD 331

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   379 HKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSV 457
Cdd:PRK07054 332 QPSLHRLPRLQHLSTPIRATLAPDATLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAhGNGDFAV 411

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 6730699   458 GIRSALVEKGLGALiYAGTGIVSGSNPSSEWNELELKISQFTKSLE 503
Cdd:PRK07054 412 ALRSALITGGACRL-FAGCGIVADSEPASEYRETCLKLSGMREALR 456
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 235-494 8.29e-44

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 159.51  E-value: 8.29e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   235 VPSEGAYYPAVNNALEIIKDkhSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPA-----FIGNT 309
Cdd:PRK06923 118 VPDPEVYMNGVKQGIAKIQD--GDLKKIVLSRSLDVKSSEKIDKQKLLRELAEHNKHGYTFAVNLPKDENensktLIGAS 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   310 PERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQ 389
Cdd:PRK06923 196 PELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHTEAMW 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   390 HLYSQLAGQLKRED-DEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFF-GGGESEFSVGIRSALVEKg 467
Cdd:PRK06923 276 HLSTEVKGELKDPNtSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREFFTGMLGWSdLNGDGEWIVTIRCAEVEE- 354

                        250       260
                 ....*....|....*....|....*...
gi 6730699   468 lGAL-IYAGTGIVSGSNPSSEWNELELK 494
Cdd:PRK06923 355 -NTLrLYAGAGVVAESKPEDELAETSAK 381
PRK15012 PRK15012
menaquinone-specific isochorismate synthase; Provisional
 25-494 5.23e-40

menaquinone-specific isochorismate synthase; Provisional


Pssm-ID: 184974 [Multi-domain]  Cd Length: 431  Bit Score: 149.99  E-value: 5.23e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699    25 SPAAATERLitavSDLKSQPPPFSSGIVRLQV--PIEQKIGAIDWLHAQnEILPRSFFSRRsdsgrpdllqdfssdNGSS 102
Cdd:PRK15012   3 SLTTALENL----LRHLSQEIPATPGIRVIDIpfPLNDAFDALSWLASQ-QTYPQFYWQQR---------------NGDE 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   103 DhnpvsVAGIGSAVFFRDLDpfshddwrSIRRFLSSKS--PLIRAYGGLRFDPTgkiavewehfgSFYFTVPQVEFDEFG 180
Cdd:PRK15012  63 E-----AAVLGAITRFTSLD--------QAQRFLRQHPehADLRIWGLNAFDPS-----------QGNLLLPRLEWRRCG 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   181 GSSMLAATVAWDNELSWTLENAIEALQEtmLQVSSVIMRLRREslgviVVSKNHVPSEGAYYPAVNNALEIIKdkHSPLS 260
Cdd:PRK15012 119 GKATLRLTLFSESSLQHDAIQAKEFLAT--LVSIKPLPGLHLT-----TTREQHWPDKTGWTQLIELATKTIA--EGELD 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   261 KVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREM 340
Cdd:PRK15012 190 KVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDAENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQ 269

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   341 EIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRkLARVQHLYSQLAGQLKREDDEFnILTALHPTPAVCG 420
Cdd:PRK15012 270 QLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLR-LRKVQHLRRCIWTSLNKADDVI-CLHQLQPTAAVAG 347

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6730699   421 CPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSALVEKGLGALiYAGTGIVSGSNPSSEWNELELK 494
Cdd:PRK15012 348 LPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKVSGNVVRL-YAGAGIVRGSDPEQEWQEIDNK 420
PRK13574 PRK13574
anthranilate synthase component I; Provisional
 236-495 3.95e-35

anthranilate synthase component I; Provisional


Pssm-ID: 184155 [Multi-domain]  Cd Length: 420  Bit Score: 136.10  E-value: 3.95e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   236 PSEGAYYPAVNNALEIIKDKHSplSKVVLARSSRIITDTDidPIAWLARLQCEGQDAYQFCLQPpGAPAFIGNTPERLFH 315
Cdd:PRK13574 155 LNKNNYEKIVSESLEYIRSGYI--FQVVLSRFYRYLFSGD--PLRIYYNLRRINPSPYMFYLKF-DERYLIGSSPELLFR 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   316 RKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTIC--DRVVVKPHKSVRKLARVQHLYS 393
Cdd:PRK13574 230 VQDNIVETYPIAGTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCvpGTVRVPELMYVEKYSHVQHIVS 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   394 QLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSALVEKGLgALI 472
Cdd:PRK13574 310 KVIGTLKKKYNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISaDGNAEFAIAIRTAFLNKDL-LRI 388

                        250       260
                 ....*....|....*....|...
gi 6730699   473 YAGTGIVSGSNPSSEWNELELKI 495
Cdd:PRK13574 389 QAGAGIVYDSNPESEYFETEHKL 411
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 229-496 2.55e-27

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 113.43  E-value: 2.55e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   229 VVSKNHVPSEGAYYPAVNNALEIIKdkhSP-LSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIG 307
Cdd:PRK15016 117 VVERQAIPEQTTFEAMVARAAALTA---TPqVDKVVLSRLIDITTDAAIDSGALLERLIAQNPVSYNFHVPLADGGVLLG 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   308 NTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLAR 387
Cdd:PRK15016 194 ASPELLLRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPT 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   388 VQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFSVGIRSALVEK 466
Cdd:PRK15016 274 LWHLATPFEGKANAQENALTLACLLHPTPALSGFPHQAAKQVIAELEPFDRELFGGIVGWCDSeGNGEWVVTIRCAKLRE 353

                        250       260       270
                 ....*....|....*....|....*....|
gi 6730699   467 GLGALiYAGTGIVSGSNPSSEWNELELKIS 496
Cdd:PRK15016 354 NQVRL-FAGAGIVPASSPLGEWRETGVKLS 382
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 5-215 4.82e-27

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 116.11  E-value: 4.82e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699      5 EADHKAPLGTVETRTLSTVPSPAAATERLITAVSDLKSQPPPFSSGIVRLQVPIEQKIGAIDWLHAQNEI---LPRSFFS 81
Cdd:PLN02980    5 NLDDDLVVEVCITRTLPPALTLELGLESLKEAVNELKLNPPASSSGVLRFQVAVPPSAKALKWFCSQPTSsdvFPVFFLS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699     82 RRSDSgrpdllqdfSSDNGSSDHNPVSVAGIGSAVFFRDLDPFSHDDWRSIRRFLSSKSPLIRAYG--GLRFDpTGKIAV 159
Cdd:PLN02980   85 KETTE---------PSYKSLYVKRPHGVFGIGNAICFVHSSSLDSNGHSMIRRYLSSESAMVTAYGfmDINFN-KESSSV 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 6730699    160 EwEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELSWTLENAIEALQETMLQVSS 215
Cdd:PLN02980  155 N-SKAGSFYFFVPQIELDEHEEVSILSATLAWDDSLSYTFEQAISSYESSIYQVSS 209
PRK13572 PRK13572
anthranilate synthase component I; Provisional
 261-503 2.93e-23

anthranilate synthase component I; Provisional


Pssm-ID: 237432 [Multi-domain]  Cd Length: 435  Bit Score: 102.12  E-value: 2.93e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   261 KVVLARSSRIitDTDIDPIAWLARLQCEGQDAYQFCLQppGAPAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREM 340
Cdd:PRK13572 193 QVVLSREYRL--KTDLSPFQLYRNLREINPSPYMFLLE--FDKDVVGASPETMASVENNILKINPIAGTAPRGKTEEEDK 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   341 EIERDLLTSPKDDLEFSIVRENIREKLKTICD--RVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAV 418
Cdd:PRK13572 269 KLAEALLSDEKERAEHVMLVDLARNDVRKVSKsgSVRLERFFDVVKYSHVQHIESEVVGELKEDSTMFDAIEAAFPAGTL 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   419 CGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSALVEKglGALIYAGTGIVSGSNPSSEWNELELKISQ 497
Cdd:PRK13572 349 TGAPKFRAMEIIDELEKSRRKVYGGAVGYFSnSGNADLAIAIRMAEIDK--VCRVRAGAGIVADSVPEKEFYETERKMAA 426


                 ....*.
gi 6730699   498 FTKSLE 503
Cdd:PRK13572 427 VLKALG 432
PRK13571 PRK13571
anthranilate synthase component I; Provisional
 237-490 5.64e-22

anthranilate synthase component I; Provisional


Pssm-ID: 184152 [Multi-domain]  Cd Length: 506  Bit Score: 98.94  E-value: 5.64e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   237 SEGAYYPAVNNALEIIKDKHSplSKVVLarSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQ---PPGAPAF--IGNTPE 311
Cdd:PRK13571 228 TVEEFGAAVEKLVEEIRAGEA--FQVVP--SQRFEMDTTADPLDVYRVLRVTNPSPYMYLLRvpnSDGGTDFsiVGSSPE 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   312 RLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICD--RVVVKPHKSVRKLARVQ 389
Cdd:PRK13571 304 ALVTVTDGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRpgTVRVVDFSHIERYSHVM 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   390 HLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSALVEKGL 468
Cdd:PRK13571 384 HLVSTVTGELAEGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDfAGDADTAIAIRTALMRDGT 463

                        250       260
                 ....*....|....*....|..
gi 6730699   469 gALIYAGTGIVSGSNPSSEWNE 490
Cdd:PRK13571 464 -AYVQAGGGVVADSDPDYEDNE 484
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 261-503 6.37e-22

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 97.87  E-value: 6.37e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  261 KVVLARssRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGApAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREM 340
Cdd:COG0147 174 QVVLSQ--RFSAPFEGDPLALYRALRRINPSPYMFYLRFGDF-AIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDA 250

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  341 EIERDLLTSPKD--------DLEfsivreniREKLKTICDR--VVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILT 410
Cdd:COG0147 251 ALAEELLADEKEraehlmlvDLA--------RNDLGRVCEPgsVKVPELMVVERYSHVMHLVSTVTGRLRPGLDALDALR 322

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699  411 ALHP--TpaVCGCP----VEearlLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSALVEKGlGALIYAGTGIVSGSN 483
Cdd:COG0147 323 ATFPagT--LTGAPkiraME----IIDELEPTRRGVYGGAVGYLSfDGNMDLAIAIRTAVVKDG-RAYVQAGAGIVADSD 395

                       250       260
                ....*....|....*....|
gi 6730699  484 PSSEWNELELKISQFTKSLE 503
Cdd:COG0147 396 PEAEYQETLNKARALLRALE 415
PRK06404 PRK06404
anthranilate synthase component I; Reviewed
 306-491 1.69e-16

anthranilate synthase component I; Reviewed


Pssm-ID: 102361 [Multi-domain]  Cd Length: 351  Bit Score: 80.68  E-value: 1.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   306 IGNTPERLFHRKHLGVCSEALAATRPrgdSKVREMEierdLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKS--VR 383
Cdd:PRK06404 165 VGSSPENVFTVNGNIINVDPIAGTYD---DKILSNE----LLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVmkIE 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   384 KLARVQHLYSQLAGQLKREDdEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSAL 463
Cdd:PRK06404 238 EFSSVKHLVSQVTAKFSNAS-YRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIISKGYTDMALVIRTAY 316

                        170       180
                 ....*....|....*....|....*...
gi 6730699   464 vEKGLGALIYAGTGIVSGSNPSSEWNEL 491
Cdd:PRK06404 317 -SHGNGFRVRAGAGIVKDSDPEDEVNEI 343
PRK06772 PRK06772
salicylate synthase;
261-502 4.35e-16

salicylate synthase;


Pssm-ID: 102546 [Multi-domain]  Cd Length: 434  Bit Score: 80.55  E-value: 4.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   261 KVVLARSsrIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAfIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREM 340
Cdd:PRK06772 193 KVIVSRA--IPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREA-LGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNK 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   341 EIERDLLTSPKDDLEFSI-VRENIREkLKTICD--RVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPA 417
Cdd:PRK06772 270 AKEAELLHDSKEVLEHILsVKEAIAE-LEAVCQpgSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSIT 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   418 VCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSALvEKGLGALIYAGTGIVSGSNPSSEWNELELKISQ 497
Cdd:PRK06772 349 ASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRSVF-QDSQRCWIQAGAGIIAQSTPERELTETREKLAS 427


                 ....*
gi 6730699   498 FTKSL 502
Cdd:PRK06772 428 IAPYL 432
PRK09070 PRK09070
aminodeoxychorismate synthase component I;
261-490 7.31e-14

aminodeoxychorismate synthase component I;


Pssm-ID: 236371 [Multi-domain]  Cd Length: 447  Bit Score: 73.58  E-value: 7.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   261 KVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGApAFIGNTPERLFhRKHLGVC-SEALAATRPRGDSkVRE 339
Cdd:PRK09070 203 QVNLSRAWQAQFANAVDPAALYARLRAANPAPFSGLFVAAGR-AIVSSSPERLV-SVQGGVVqTRPIAGTRPRFAG-DDD 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   340 MEIERDLLTSPKD--------DLEfsivreniREKLKTIC--DRVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNIL 409
Cdd:PRK09070 280 AALIRELVGHPKEraehvmliDLE--------RNDLGRICapGSVEVDELMTVESYAHVHHIVSNVRGRLRDGVTPGEVI 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   410 TALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSALVEkglGALIY--AGTGIVSGSNPSS 486
Cdd:PRK09070 352 RAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNrDGDMDLNILIRTAEVQ---GNQVRfrTGAGIVVDSDPER 428


                 ....
gi 6730699   487 EWNE 490
Cdd:PRK09070 429 ELDE 432
PRK07508 PRK07508
aminodeoxychorismate synthase component I;
301-494 4.24e-13

aminodeoxychorismate synthase component I;


Pssm-ID: 236035 [Multi-domain]  Cd Length: 378  Bit Score: 70.81  E-value: 4.24e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   301 GAPAFIGNTPERLFHRKhlgvcSEALAATRP------RGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRV 374
Cdd:PRK07508 169 GGPVILSRSPELFFRVD-----GEGWIETHPmkgtapRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRISEVG 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   375 VVKPHK--SVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GG 451
Cdd:PRK07508 244 SLDVPElfDIETYPTVHQMVSRVRARLLPGLGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIApDG 323

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 6730699   452 ESEFSVGIRSALVEKGLGALIYAGTGIVSGSNPSSEWNELELK 494
Cdd:PRK07508 324 RMRFNVAIRTLSLFPGGRAVFNVGGGIVFDSTAEAEYEECLLK 366
PRK05940 PRK05940
anthranilate synthase component I;
304-490 7.22e-13

anthranilate synthase component I;


Pssm-ID: 235651 [Multi-domain]  Cd Length: 463  Bit Score: 70.53  E-value: 7.22e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   304 AFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICD--RVVVKPHKS 381
Cdd:PRK05940 250 DVVSCSPERLVQLQGNQAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQwgSVEVDELLT 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   382 VRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIR 460
Cdd:PRK05940 330 IERYSHVIHLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDqRGNLDLNILIR 409

                        170       180       190
                 ....*....|....*....|....*....|....
gi 6730699   461 SALVEK--GLGALIYA--GTGIVSGSNPSSEWNE 490
Cdd:PRK05940 410 TLLYTPlsRGLSTIWGqvGAGIVADSDPEKEWLE 443
PRK07912 PRK07912
salicylate synthase;
292-490 3.41e-12

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 68.28  E-value: 3.41e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   292 AYQFCLQPPGAPAfIGNTPERLFHRKHLG-VCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSI-VRENIREkLKT 369
Cdd:PRK07912 233 VRSFLLRLGGIRA-LGYSPELVTAVRADGvVITEPLAGTRAFGRGAAIDRLARDDLESNSKEIVEHAIsVRSSLAE-ITE 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   370 ICD--RVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGF 447
Cdd:PRK07912 311 IAEpgSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVM 390

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6730699   448 FGG-GESEFSVGIRSALVEKGlGALIYAGTGIVSGSNPSSEWNE 490
Cdd:PRK07912 391 LSAdGGLDAALTLRAAYQVGG-RTWLRAGAGIIEESEPEREFEE 433
PRK05877 PRK05877
aminodeoxychorismate synthase component I; Provisional
 309-490 9.82e-12

aminodeoxychorismate synthase component I; Provisional


Pssm-ID: 235634 [Multi-domain]  Cd Length: 405  Bit Score: 66.65  E-value: 9.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   309 TPERLFHRKHLGVCSEALAATRPRGDSKVRemeierdLLTSPKDdlefsiVRENI------REKLKTICD--RVVVKPHK 380
Cdd:PRK05877 207 SPELFLRRRGSVVTSSPIKGTLPLDADPSA-------LRASAKD------VAENImivdlvRNDLGRVARtgTVTVPELL 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   381 SVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGI 459
Cdd:PRK05877 274 VVRPAPGVWHLVSTVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASpVAGCELNVAI 353

                        170       180       190
                 ....*....|....*....|....*....|.
gi 6730699   460 RSALVEKGLGALIYAGTGIVSGSNPSSEWNE 490
Cdd:PRK05877 354 RTVEFDADGNAVLGVGGGITADSDPDAEWQE 384
PRK13567 PRK13567
anthranilate synthase component I; Provisional
 303-502 9.30e-11

anthranilate synthase component I; Provisional


Pssm-ID: 184148 [Multi-domain]  Cd Length: 468  Bit Score: 64.01  E-value: 9.30e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   303 PAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHK-- 380
Cdd:PRK13567 266 PYIVGSSPESFVSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVSKIGTSKITKlm 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   381 SVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGES-EFSVGI 459
Cdd:PRK13567 346 VIEKYEHVMHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPHKRGVYSGGVGYINCNHNlDFALAI 425

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 6730699   460 RSALVEKGLgALIYAGTGIVSGSNPSSEWNELELKisqfTKSL 502
Cdd:PRK13567 426 RTMMIDEQY-INVEAGCGVVYDSIPEKELNETKLK----AKSL 463
PLN02445 PLN02445
anthranilate synthase component I
 309-494 1.82e-10

anthranilate synthase component I


Pssm-ID: 215244 [Multi-domain]  Cd Length: 523  Bit Score: 63.16  E-value: 1.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   309 TPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIV----RENIREKLKTicDRVVVKPHKSVRK 384
Cdd:PLN02445 301 SPEILTRVKKNKIVNRPLAGTRRRGKTPEEDKALEKDLLADEKQCAEHIMLvdlgRNDVGKVSKA--GSVKVEKLMNIER 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   385 LARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSAL 463
Cdd:PLN02445 379 YSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRAMELIDELEVTRRGPYSGGFGGVSfTGDMDIALALRTMV 458

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 6730699   464 VEKGLG-----------------ALIYAGTGIVSGSNPSSEWNELELK 494
Cdd:PLN02445 459 FPTAARydtmysykdtnsrrewvAHLQAGAGIVADSDPEDEYRECVNK 506
PLN02889 PLN02889
oxo-acid-lyase/anthranilate synthase
 241-494 1.94e-10

oxo-acid-lyase/anthranilate synthase


Pssm-ID: 215481 [Multi-domain]  Cd Length: 918  Bit Score: 63.33  E-value: 1.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   241 YYPAVNNALEIIKDKHSPLSKVVLARSSRIitdTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFI-GNTPERLFHRKHL 319
Cdd:PLN02889 646 YIKDVQKCLKYIKDGESYELCLTTQMRKRI---GEIDSLGLYLHLREKNPAPYAAWLNFSNENLCIcSSSPERFLKLDRN 722

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   320 GVC-SEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICD--RVVVKPHKSVRKLARVQHLYSQLA 396
Cdd:PLN02889 723 GMLeAKPIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEpgSVHVPNLMDVESYTTVHTMVSTIR 802

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   397 GQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFSVGIRSALVEKGlGALIYAG 475
Cdd:PLN02889 803 GKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSyNQTFDLNIVIRTVVIHEG-EASIGAG 881

                        250
                 ....*....|....*....
gi 6730699   476 TGIVSGSNPSSEWNELELK 494
Cdd:PLN02889 882 GAIVALSNPEDEYEEMILK 900
PRK13564 PRK13564
anthranilate synthase component 1;
327-490 1.71e-09

anthranilate synthase component 1;


Pssm-ID: 237428 [Multi-domain]  Cd Length: 520  Bit Score: 60.23  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   327 AATRPRG-----------DSKvremeIERDLLTSPKD--------DLEfsivreniREKLKTICD---RVVVKPHKsVRK 384
Cdd:PRK13564 327 AGTRPRGrradgsidrdlDSR-----IELELRTDHKElaehlmlvDLA--------RNDLARICQpgsRYVADLLK-VDR 392

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   385 LARVQHLYSQLAGQLkREDdefniLTALHPTPAvC-------GCPVEEARLLIKQIESFDRGMYAGPIGFFGG-GESEFS 456
Cdd:PRK13564 393 YSHVMHLVSRVVGEL-RHD-----LDALHAYRA-CmnmgtltGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGhGDLDTC 465

                        170       180       190
                 ....*....|....*....|....*....|....
gi 6730699   457 VGIRSALVEKGLgALIYAGTGIVSGSNPSSEWNE 490
Cdd:PRK13564 466 IVIRSAFVENGI-ATVQAGAGVVLDSDPQSEADE 498
PRK07093 PRK07093
para-aminobenzoate synthase component I; Validated
 343-495 2.08e-08

para-aminobenzoate synthase component I; Validated


Pssm-ID: 235932 [Multi-domain]  Cd Length: 323  Bit Score: 56.03  E-value: 2.08e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   343 ERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKL----ARVQHLYSQLAGQLKREDDEF--NILTALHPTP 416
Cdd:PRK07093 161 EEKLLNDEKEFAEHATIVDLLRNDLSMVAKNVRVTRFRYIDKIktnkGEILQTSSEISGTLPENWQENigDILAKLLPAG 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   417 AVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRsaLVEKGLGALIY-AGTGIVSGSNPSSEWNELELKI 495
Cdd:PRK07093 241 SITGAPKEKTVEIIEQAEGYERGFYTGVFGYFDGESLDSAVMIR--FIEQENDGLYFkSGGGITIDSDLKDEYNELIQKV 318
pabB PRK15465
aminodeoxychorismate synthase component 1;
304-503 2.43e-07

aminodeoxychorismate synthase component 1;


Pssm-ID: 185362 [Multi-domain]  Cd Length: 453  Bit Score: 53.00  E-value: 2.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   304 AFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLkticDRVVVKPHKSVR 383
Cdd:PRK15465 251 AILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDI----GRVAVAGSVKVP 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6730699   384 KL------ARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFG-GGESEFS 456
Cdd:PRK15465 327 ELfvvepfPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSfCGNMDTS 406

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 6730699   457 VGIRSALVEKGlgaLIY--AGTGIVSGSNPSSEWNELELKISQFTKSLE 503
Cdd:PRK15465 407 ITIRTLTAING---QIYcsAGGGIVADSQEEAEYQETFDKVNRILRQLE 452
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH