putative E1-E2 ATPase, partial [Mus musculus]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | |||||
| PhoLip_ATPase_C | pfam16212 | Phospholipid-translocating P-type ATPase C-terminal; PhoLip_ATPase_C is found at the ... |
1-251 | 8.48e-104 | |||||
Phospholipid-translocating P-type ATPase C-terminal; PhoLip_ATPase_C is found at the C-terminus of a number of phospholipid-translocating ATPases. It is found in higher eukaryotes. : Pssm-ID: 465071 [Multi-domain] Cd Length: 250 Bit Score: 305.20 E-value: 8.48e-104
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| Name | Accession | Description | Interval | E-value | |||||
| PhoLip_ATPase_C | pfam16212 | Phospholipid-translocating P-type ATPase C-terminal; PhoLip_ATPase_C is found at the ... |
1-251 | 8.48e-104 | |||||
Phospholipid-translocating P-type ATPase C-terminal; PhoLip_ATPase_C is found at the C-terminus of a number of phospholipid-translocating ATPases. It is found in higher eukaryotes. Pssm-ID: 465071 [Multi-domain] Cd Length: 250 Bit Score: 305.20 E-value: 8.48e-104
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| P-type_ATPase_APLT_Dnf-like | cd02073 | Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, ... |
1-129 | 6.20e-73 | |||||
Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C; Aminophospholipid translocases (APLTs), also known as type 4 P-type ATPases, act as flippases, and translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes. Yeast Dnf1 and Dnf2 mediate the transport of phosphatidylethanolamine, phosphatidylserine, and phosphatidylcholine from the outer to the inner leaflet of the plasma membrane. This subfamily includes mammalian flippases such as ATP11C which may selectively transports PS and PE from the outer leaflet of the plasma membrane to the inner leaflet. It also includes Arabidopsis phospholipid flippases including ALA1, and Caenorhabditis elegans flippases, including TAT-1, the latter has been shown to facilitate the inward transport of phosphatidylserine. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. Pssm-ID: 319770 [Multi-domain] Cd Length: 836 Bit Score: 241.69 E-value: 6.20e-73
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| ATPase-Plipid | TIGR01652 | phospholipid-translocating P-type ATPase, flippase; This model describes the P-type ATPase ... |
1-257 | 5.42e-71 | |||||
phospholipid-translocating P-type ATPase, flippase; This model describes the P-type ATPase responsible for transporting phospholipids from one leaflet of bilayer membranes to the other. These ATPases are found only in eukaryotes. Pssm-ID: 273734 [Multi-domain] Cd Length: 1057 Bit Score: 238.82 E-value: 5.42e-71
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| PLN03190 | PLN03190 | aminophospholipid translocase; Provisional |
1-251 | 1.02e-37 | |||||
aminophospholipid translocase; Provisional Pssm-ID: 215623 [Multi-domain] Cd Length: 1178 Bit Score: 143.89 E-value: 1.02e-37
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| Name | Accession | Description | Interval | E-value | |||||
| PhoLip_ATPase_C | pfam16212 | Phospholipid-translocating P-type ATPase C-terminal; PhoLip_ATPase_C is found at the ... |
1-251 | 8.48e-104 | |||||
Phospholipid-translocating P-type ATPase C-terminal; PhoLip_ATPase_C is found at the C-terminus of a number of phospholipid-translocating ATPases. It is found in higher eukaryotes. Pssm-ID: 465071 [Multi-domain] Cd Length: 250 Bit Score: 305.20 E-value: 8.48e-104
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| P-type_ATPase_APLT_Dnf-like | cd02073 | Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, ... |
1-129 | 6.20e-73 | |||||
Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C; Aminophospholipid translocases (APLTs), also known as type 4 P-type ATPases, act as flippases, and translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes. Yeast Dnf1 and Dnf2 mediate the transport of phosphatidylethanolamine, phosphatidylserine, and phosphatidylcholine from the outer to the inner leaflet of the plasma membrane. This subfamily includes mammalian flippases such as ATP11C which may selectively transports PS and PE from the outer leaflet of the plasma membrane to the inner leaflet. It also includes Arabidopsis phospholipid flippases including ALA1, and Caenorhabditis elegans flippases, including TAT-1, the latter has been shown to facilitate the inward transport of phosphatidylserine. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. Pssm-ID: 319770 [Multi-domain] Cd Length: 836 Bit Score: 241.69 E-value: 6.20e-73
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| ATPase-Plipid | TIGR01652 | phospholipid-translocating P-type ATPase, flippase; This model describes the P-type ATPase ... |
1-257 | 5.42e-71 | |||||
phospholipid-translocating P-type ATPase, flippase; This model describes the P-type ATPase responsible for transporting phospholipids from one leaflet of bilayer membranes to the other. These ATPases are found only in eukaryotes. Pssm-ID: 273734 [Multi-domain] Cd Length: 1057 Bit Score: 238.82 E-value: 5.42e-71
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| PLN03190 | PLN03190 | aminophospholipid translocase; Provisional |
1-251 | 1.02e-37 | |||||
aminophospholipid translocase; Provisional Pssm-ID: 215623 [Multi-domain] Cd Length: 1178 Bit Score: 143.89 E-value: 1.02e-37
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| P-type_ATPase_APLT | cd07536 | Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, ... |
1-126 | 6.69e-29 | |||||
Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, Neo1p, and human ATP8A2, -9B, -10D, -11B, and -11C; Aminophospholipid translocases (APLTs), also known as type 4 P-type ATPases, act as flippases, and translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes. Yeast Dnf1 and Dnf2 mediate the transport of phosphatidylethanolamine, phosphatidylserine, and phosphatidylcholine from the outer to the inner leaflet of the plasma membrane. Mammalian ATP11C may selectively transports PS and PE from the outer leaflet of the plasma membrane to the inner leaflet. The yeast Neo1p localizes to the endoplasmic reticulum and the Golgi complex and plays a role in membrane trafficking within the endomembrane system. Human putative ATPase phospholipid transporting 9B, ATP9B, localizes to the trans-golgi network in a CDC50 protein-independent manner. It also includes Arabidopsis phospholipid flippases including ALA1, and Caenorhabditis elegans flippases, including TAT-1, the latter has been shown to facilitate the inward transport of phosphatidylserine. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. Pssm-ID: 319838 [Multi-domain] Cd Length: 805 Bit Score: 117.70 E-value: 6.69e-29
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| P-type_ATPase_APLT_Neo1-like | cd07541 | Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Neo1p and human ... |
1-127 | 1.57e-15 | |||||
Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Neo1p and human putative APLT, ATP9B; Aminophospholipid translocases (APLTs), also known as type 4 P-type ATPases, act as a flippases, and translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes. The yeast Neo1 gene is an essential gene; Neo1p localizes to the endoplasmic reticulum and the Golgi complex and plays a role in membrane trafficking within the endomembrane system. Also included in this sub family is human putative ATPase phospholipid transporting 9B, ATP9B, which localizes to the trans-golgi network in a CDC50 protein-independent manner. Levels of ATP9B, along with levels of other ATPase genes, may contribute to expressivity of and atypical presentations of Hailey-Hailey disease (HHD), and the ATP9B gene has recently been identified as a putative Alzheimer's disease loci. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. Pssm-ID: 319841 [Multi-domain] Cd Length: 792 Bit Score: 77.83 E-value: 1.57e-15
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