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Conserved domains on  [gi|4928751|gb|AAD33716|]
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YABBY2 [Arabidopsis thaliana]

Protein Classification

YABBY transcription factor( domain architecture ID 10520082)

YABBY transcription factor is involved in the initiation of outgrowth of the lamina, the maintenance of polarity, and establishment of the leaf margin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YABBY pfam04690
YABBY protein; YABBY proteins are a group of plant-specific transcription involved in the ...
5-160 1.96e-97

YABBY protein; YABBY proteins are a group of plant-specific transcription involved in the specification of abaxial polarity in lateral organs.


:

Pssm-ID: 461393  Cd Length: 163  Bit Score: 278.80  E-value: 1.96e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4928751      5 FSSERVCYVHCSFCTTILAVSVPYASLFTLVTVRCGHCTNLLSLNIGVSLHQtsapPIHQDLQP--HRQHTTSLVTRKDC 82
Cdd:pfam04690   1 DPSEQLCYVHCNFCNTILAVSVPCSSLFKTVTVRCGHCTNLLSVNMRGLLQV----PLAQDLQSlsHQLHLSSLGNSLEQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4928751     83 ASSSRSTNNL-------SENIDREAPR--MPPIRPPEKRQRVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWAHF 153
Cdd:pfam04690  77 GSSSSSSNNSntstamySSSSAQEEPEdpPVVNRPPEKRQRVPSAYNRFIKEEIQRIKAGNPDISHREAFSTAAKNWAHF 156

                  ....*..
gi 4928751    154 PHIHFGL 160
Cdd:pfam04690 157 PHIHFGL 163
 
Name Accession Description Interval E-value
YABBY pfam04690
YABBY protein; YABBY proteins are a group of plant-specific transcription involved in the ...
5-160 1.96e-97

YABBY protein; YABBY proteins are a group of plant-specific transcription involved in the specification of abaxial polarity in lateral organs.


Pssm-ID: 461393  Cd Length: 163  Bit Score: 278.80  E-value: 1.96e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4928751      5 FSSERVCYVHCSFCTTILAVSVPYASLFTLVTVRCGHCTNLLSLNIGVSLHQtsapPIHQDLQP--HRQHTTSLVTRKDC 82
Cdd:pfam04690   1 DPSEQLCYVHCNFCNTILAVSVPCSSLFKTVTVRCGHCTNLLSVNMRGLLQV----PLAQDLQSlsHQLHLSSLGNSLEQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4928751     83 ASSSRSTNNL-------SENIDREAPR--MPPIRPPEKRQRVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWAHF 153
Cdd:pfam04690  77 GSSSSSSNNSntstamySSSSAQEEPEdpPVVNRPPEKRQRVPSAYNRFIKEEIQRIKAGNPDISHREAFSTAAKNWAHF 156

                  ....*..
gi 4928751    154 PHIHFGL 160
Cdd:pfam04690 157 PHIHFGL 163
HMG-box_SF cd00084
high mobility group (HMG)-box domain superfamily; The High Mobility Group (HMG)-box is found ...
114-150 7.63e-05

high mobility group (HMG)-box domain superfamily; The High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenetically distinct groups of Class I proteins bind DNA in a sequence specific fashion and contain a single HMG box. One group (SOX-TCF) includes transcription factors, TCF-1, -3, -4, and also SRY and LEF-1, which bind four-way DNA junctions and duplex DNA targets. The second group (MATA) includes fungal mating type gene products MC, MATA1 and Ste11. Class II and III proteins (HMGB-UBF) bind DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal proteins, HMG1 and HMG2, which bind to bent or distorted DNA such as four-way DNA junctions, synthetic DNA cruciforms, kinked cisplatin-modified DNA, DNA bulges, cross-overs in supercoiled DNA, and can cause looping of linear DNA. Class III members include nucleolar and mitochondrial transcription factors, UBF and mtTF1, which bind four-way DNA junctions.


Pssm-ID: 438789 [Multi-domain]  Cd Length: 59  Bit Score: 39.04  E-value: 7.63e-05
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 4928751  114 RVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNW 150
Cdd:cd00084   1 RPLSAYLLFSKEKRPKLKKENPDLSFTEISKLLGERW 37
 
Name Accession Description Interval E-value
YABBY pfam04690
YABBY protein; YABBY proteins are a group of plant-specific transcription involved in the ...
5-160 1.96e-97

YABBY protein; YABBY proteins are a group of plant-specific transcription involved in the specification of abaxial polarity in lateral organs.


Pssm-ID: 461393  Cd Length: 163  Bit Score: 278.80  E-value: 1.96e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4928751      5 FSSERVCYVHCSFCTTILAVSVPYASLFTLVTVRCGHCTNLLSLNIGVSLHQtsapPIHQDLQP--HRQHTTSLVTRKDC 82
Cdd:pfam04690   1 DPSEQLCYVHCNFCNTILAVSVPCSSLFKTVTVRCGHCTNLLSVNMRGLLQV----PLAQDLQSlsHQLHLSSLGNSLEQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4928751     83 ASSSRSTNNL-------SENIDREAPR--MPPIRPPEKRQRVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWAHF 153
Cdd:pfam04690  77 GSSSSSSNNSntstamySSSSAQEEPEdpPVVNRPPEKRQRVPSAYNRFIKEEIQRIKAGNPDISHREAFSTAAKNWAHF 156

                  ....*..
gi 4928751    154 PHIHFGL 160
Cdd:pfam04690 157 PHIHFGL 163
HMG-box_SF cd00084
high mobility group (HMG)-box domain superfamily; The High Mobility Group (HMG)-box is found ...
114-150 7.63e-05

high mobility group (HMG)-box domain superfamily; The High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenetically distinct groups of Class I proteins bind DNA in a sequence specific fashion and contain a single HMG box. One group (SOX-TCF) includes transcription factors, TCF-1, -3, -4, and also SRY and LEF-1, which bind four-way DNA junctions and duplex DNA targets. The second group (MATA) includes fungal mating type gene products MC, MATA1 and Ste11. Class II and III proteins (HMGB-UBF) bind DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal proteins, HMG1 and HMG2, which bind to bent or distorted DNA such as four-way DNA junctions, synthetic DNA cruciforms, kinked cisplatin-modified DNA, DNA bulges, cross-overs in supercoiled DNA, and can cause looping of linear DNA. Class III members include nucleolar and mitochondrial transcription factors, UBF and mtTF1, which bind four-way DNA junctions.


Pssm-ID: 438789 [Multi-domain]  Cd Length: 59  Bit Score: 39.04  E-value: 7.63e-05
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 4928751  114 RVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNW 150
Cdd:cd00084   1 RPLSAYLLFSKEKRPKLKKENPDLSFTEISKLLGERW 37
HMG-box_UBF1_rpt4 cd22001
fourth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar ...
110-154 2.28e-04

fourth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar proteins; UBF1, also called UBTF, nucleolar transcription factor 1, or auto-antigen NOR-90, is a nucleolar transcription factor that recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. UBF1 contains six HMG-box domains. This model corresponds to the fourth one.


Pssm-ID: 438817 [Multi-domain]  Cd Length: 66  Bit Score: 38.05  E-value: 2.28e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 4928751  110 EKRQRVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWAHFP 154
Cdd:cd22001   1 EKPKRPISAMFIYSKEKRSKLKKKHPELSEQELTRLLAKKYNELP 45
HMG_box_2 pfam09011
HMG-box domain; This short 71 residue domain is an HMG-box domain. HMG-box domains mediate ...
109-151 5.30e-04

HMG-box domain; This short 71 residue domain is an HMG-box domain. HMG-box domains mediate re-modelling of chromatin-structure. Mammalian HMG-box proteins are of two types: those that are non-sequence-specific DNA-binding proteins with two HMG-box domains and a long highly acidic C-tail; and a diverse group of sequence-specific transcription factor-proteins with either a single HMG-box or up to six copies, and no acidic C-tail.


Pssm-ID: 430369 [Multi-domain]  Cd Length: 72  Bit Score: 37.00  E-value: 5.30e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 4928751    109 PEKRQRVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWA 151
Cdd:pfam09011   1 PNKPKRARNAYAFFVQEMIPEHKRQNPVIGFAEVSKLCSERWK 43
HMG-box_HMG20 cd21980
high mobility group (HMG)-box found in the high mobility group protein 20 (HMG20) subfamily; ...
100-173 4.20e-03

high mobility group (HMG)-box found in the high mobility group protein 20 (HMG20) subfamily; The HMG20 subfamily includes HMG20A and HMG20B. HMG20A, also called HMG box-containing protein 20A, HMG domain-containing protein 1, HMG domain-containing protein HMGX1, HMGXB1, or iBRAF, is a chromatin-associated protein involved in neuronal differentiation and maturation. It is required for SNAI1-mediated epithelial to mesenchymal transition. HMG20A acts as an inhibitor of HMG20B. HMG20B, also called SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, SMARCE1-related protein (SMARCE1R), BRCA2-associated factor 35 (BRAF35), HMG box-containing protein 20B, HMG domain-containing protein 2, HMG domain-containing protein HMGX2, Sox-like transcriptional factor, or structural DNA-binding protein BRAF35, is a DNA binding factor that acts as a repressor of erythroid differentiation. It is required for correct progression through the G2 phase of the cell cycle and entry into mitosis. It is also required for RCOR1/CoREST mediated repression of neuronal specific gene promoters. HMG20B is a core subunit of the Lys-specific demethylase 1/REST co-repressor 1 (LSD1-CoREST) histone demethylase complex. Both HMG20A and HMG20B contain one HMG-box.


Pssm-ID: 438796 [Multi-domain]  Cd Length: 81  Bit Score: 34.83  E-value: 4.20e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4928751  100 APRMPPirppekrqrvpSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWAhfphihfglKLDGNKKGKQLDQ 173
Cdd:cd21980   1 APKAPL-----------TGYVRFLNERREKLRAENPDLSFPEITKILGAEWS---------SLSAEEKQKYLDE 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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