|
Name |
Accession |
Description |
Interval |
E-value |
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
78-468 |
8.92e-86 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 274.39 E-value: 8.92e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 78 YVRNYPHDG*ASHTVGYISTQY-----GTAGIESS*NETLTGH---------ADHSDWRSALYS*AGINttGSSVVLTIN 143
Cdd:COG0768 149 YKRYYPYGELAAHVLGYVGEINggdgiGKSGLEKAYEDLLRGTpgkrrvevdARGRVIRDLGEEKPPVP--GKDLVLTID 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 144 SQ*QAVAEAALQGY-------SGSIVV*DPSTGAVLAKASSPSYthaELGTIIEsGTGSQLVDRTTQALYSPGSSFKTVT 216
Cdd:COG0768 227 SDLQKIAEEALKKAveeykakSGAVVVMDPKTGEILAMASYPSF---DPNLFVG-GPDEPLRNRAVQGTYEPGSTFKPFT 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 217 LAAGIDTHKTTLDTTYSAPGT*EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALG 296
Cdd:COG0768 303 AAAALEEGVITPDTTFDCPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKTG 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 297 QDFST-TPSL*PNPAE*TTWELAWASCG---------LpVGEHASPAGpqttv*qnaviaaaianGGVV*NPYIVDRVLS 366
Cdd:COG0768 383 IDLPGeASGLLPSPKRWYPGETATMSIGqglsvtplqL-AQAYAAIAN-----------------GGVLVKPHLVKEIVD 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 367 PEGAVVSTTsPKSLGQAVSADTAAQVREA*LGVVES--GTG*GARVPGVKIAGKTGTADV--------ENGNFNSFFIGF 436
Cdd:COG0768 445 PDGEVVKEE-PEVLRRVISPETAETVREGMEGVVNEpgGTARRAAIPGYRVAGKTGTAQVvdignggyYKGRHIASFVGF 523
|
410 420 430
....*....|....*....|....*....|..
4JBF_A 437 APYDHPTLVVSVVIEgNGENVlGYGAQVGGRV 468
Cdd:COG0768 524 APADNPRYAVAVVVE-NPGGG-AYGGTVAAPV 553
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
78-466 |
2.07e-64 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 218.55 E-value: 2.07e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 78 YVRNYPHDG*ASHTVGYIS------------------TQYGTAGIESS*NETLTGHADHSD--------WRSALYS*AGI 131
Cdd:TIGR03423 144 LKRYYPYGELAAHVLGYVGeineedlerlepanyaggDYIGKSGIEKYYEDELRGKPGYREvevnargrVIRTLSRVPPV 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 132 NttGSSVVLTINSQ*QAVAEAALQGYSGSIVV*DPSTGAVLAKASSPSY---------THAELGTIIESgTGSQLVDRTT 202
Cdd:TIGR03423 224 P--GKDLVLTIDARLQQAAEKALGGRRGAVVVMDPRTGEILAMVSTPSFdpnlfvdgiSSKDYKALLND-PDRPLLNRAI 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 203 QALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGT*EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNL 282
Cdd:TIGR03423 301 QGVYPPGSTFKPVVALAALEEGVITPETRIYCPGYFQLGGRRFRCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGIDKI 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 283 VSYARAFGYGTALGQD-FSTTPSL*PNPA-E*TTWELAWAscglpVGEHASPAGPQ----TTV*QNAVIAAAIANGGVV* 356
Cdd:TIGR03423 381 AEYAKRFGFGQKTGIDlPGEKSGLVPSREwKRKRFGQPWY-----PGDTLNVSIGQgyvlVTPLQLAVATAALANGGKLY 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 357 NPYIVDRVLSPEGAVVSTTSPKSLGQA-VSADTAAQVREA*LGVVES--GTG*GARVP-GVKIAGKTGTADV----ENGN 428
Cdd:TIGR03423 456 KPHLVKSIEDPDGGVVRRTEPEVLRPLpISPENLDVVREGMRDVVNGpgGTARRARLGlPYKMAGKTGTAQVvslkQGEK 535
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
4JBF_A 429 FN-----------SFFIGFAPYDHPTLVVSVVIEgNGenvlGYGAQVGG 466
Cdd:TIGR03423 536 YDaeqiperlrdhALFVAFAPYDNPKIAVAVIVE-HG----GGGSSAAA 579
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
159-454 |
2.33e-42 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 152.19 E-value: 2.33e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 159 GSIVV*DPSTGAVLAKASSPSYThaelgtiiESGTGSQLVDRTTQALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGT* 238
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYD--------PNGFIGPLRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 239 EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALGQDFSTTPSL*PNPAe*ttW-EL 317
Cdd:pfam00905 73 QQGGKSIGDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGENAGYLTPY----WlEG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 318 AWASCGLPVGehASP---AGPQTTv*qnaviaaaIANGGVV*NPYIVDRVlspegaVVSTTSPKSLGQAVSADTAAQVRE 394
Cdd:pfam00905 149 ATASFGIGLT--ITPlqqAQAYAA----------IANGGKLVPPHLVKSI------EDKVDPKVLNKLPISKSTAEKVKD 210
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
4JBF_A 395 A*LGVVESGTG*G-ARVPGVKIAGKTGTADV--------ENGNFNSFFIGFAPYDHPTLVVSVVIEGNG 454
Cdd:pfam00905 211 MLRLVVNDGTGTGtAAVPGYKVAGKTGTAQVagpkgggyYDGAQIGWFVGYAPADNPKYAFAVLIDDPK 279
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
80-465 |
8.53e-15 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 76.73 E-value: 8.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 80 RNYPHDG*ASHTVGYIST----------------------QYGTAGIESS*NETLTGHADhsdwrsalYS*AGINT---- 133
Cdd:PRK10795 165 RYYPYGSALTHVIGYVSKindkdverldkegklanyaathDIGKLGIERYYEDVLHGKTG--------YEEVEVNNrgrv 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 134 ----------TGSSVVLTINSQ*QAVAEAALQGYSGSIVV*DPSTGAVLAKASSPSYTHAELGTIIESGTGSQ------- 196
Cdd:PRK10795 237 irqlheqppqAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGILALVSTPSYDPNLFVDGISSKDYSGllndpnr 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 197 -LVDRTTQALYSPGSSFK----TVTLAAGIDTHKTTLdttySAPGT*EIGGGT--IHNYANED*GTIPLREAFARSSNTA 269
Cdd:PRK10795 317 pLINRATQGVYPPASTVKpyvaVSALSAGVITRNTSL----FDPGWWQLPGSEkrYRDWKKWGHGRLNVTKSLEESADTF 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 270 LAQLGVALGADNLVSYARAFGYGTALGQDFS-TTPSL*Pnpae*TTWELA------WASCGLPVGehaSPAGPQT-TV*Q 341
Cdd:PRK10795 393 FYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAeERSGNMP----TREWKQKrfkkpwYQGDTIPVG---IGQGYWTaTPIQ 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 342 NAVIAAAIANGGVV*NPYIVdRVLSPEGAVVSTTSPKS--LGQAVSA--DTAaqvREA*LGVVESGTG*G----ARVPgV 413
Cdd:PRK10795 466 MSKALMTLINDGIVKVPHLL-MSTAEDGKQVPWVQPHEppVGDIHSGywEIA---KDGMYGVANRPNGTAhkyfASAP-Y 540
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
4JBF_A 414 KIAGKTGTADV----ENGNFNS-----------FFIGFAPYDHPTLVVSVVIEgNGenvlGYGAQVG 465
Cdd:PRK10795 541 KIAAKSGTAQVfglkANETYNAhkiaerlrdhkLMTAFAPYNNPQVAVAIILE-NG----GAGPAVG 602
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
78-468 |
8.92e-86 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 274.39 E-value: 8.92e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 78 YVRNYPHDG*ASHTVGYISTQY-----GTAGIESS*NETLTGH---------ADHSDWRSALYS*AGINttGSSVVLTIN 143
Cdd:COG0768 149 YKRYYPYGELAAHVLGYVGEINggdgiGKSGLEKAYEDLLRGTpgkrrvevdARGRVIRDLGEEKPPVP--GKDLVLTID 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 144 SQ*QAVAEAALQGY-------SGSIVV*DPSTGAVLAKASSPSYthaELGTIIEsGTGSQLVDRTTQALYSPGSSFKTVT 216
Cdd:COG0768 227 SDLQKIAEEALKKAveeykakSGAVVVMDPKTGEILAMASYPSF---DPNLFVG-GPDEPLRNRAVQGTYEPGSTFKPFT 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 217 LAAGIDTHKTTLDTTYSAPGT*EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALG 296
Cdd:COG0768 303 AAAALEEGVITPDTTFDCPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKTG 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 297 QDFST-TPSL*PNPAE*TTWELAWASCG---------LpVGEHASPAGpqttv*qnaviaaaianGGVV*NPYIVDRVLS 366
Cdd:COG0768 383 IDLPGeASGLLPSPKRWYPGETATMSIGqglsvtplqL-AQAYAAIAN-----------------GGVLVKPHLVKEIVD 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 367 PEGAVVSTTsPKSLGQAVSADTAAQVREA*LGVVES--GTG*GARVPGVKIAGKTGTADV--------ENGNFNSFFIGF 436
Cdd:COG0768 445 PDGEVVKEE-PEVLRRVISPETAETVREGMEGVVNEpgGTARRAAIPGYRVAGKTGTAQVvdignggyYKGRHIASFVGF 523
|
410 420 430
....*....|....*....|....*....|..
4JBF_A 437 APYDHPTLVVSVVIEgNGENVlGYGAQVGGRV 468
Cdd:COG0768 524 APADNPRYAVAVVVE-NPGGG-AYGGTVAAPV 553
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
78-466 |
2.07e-64 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 218.55 E-value: 2.07e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 78 YVRNYPHDG*ASHTVGYIS------------------TQYGTAGIESS*NETLTGHADHSD--------WRSALYS*AGI 131
Cdd:TIGR03423 144 LKRYYPYGELAAHVLGYVGeineedlerlepanyaggDYIGKSGIEKYYEDELRGKPGYREvevnargrVIRTLSRVPPV 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 132 NttGSSVVLTINSQ*QAVAEAALQGYSGSIVV*DPSTGAVLAKASSPSY---------THAELGTIIESgTGSQLVDRTT 202
Cdd:TIGR03423 224 P--GKDLVLTIDARLQQAAEKALGGRRGAVVVMDPRTGEILAMVSTPSFdpnlfvdgiSSKDYKALLND-PDRPLLNRAI 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 203 QALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGT*EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNL 282
Cdd:TIGR03423 301 QGVYPPGSTFKPVVALAALEEGVITPETRIYCPGYFQLGGRRFRCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGIDKI 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 283 VSYARAFGYGTALGQD-FSTTPSL*PNPA-E*TTWELAWAscglpVGEHASPAGPQ----TTV*QNAVIAAAIANGGVV* 356
Cdd:TIGR03423 381 AEYAKRFGFGQKTGIDlPGEKSGLVPSREwKRKRFGQPWY-----PGDTLNVSIGQgyvlVTPLQLAVATAALANGGKLY 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 357 NPYIVDRVLSPEGAVVSTTSPKSLGQA-VSADTAAQVREA*LGVVES--GTG*GARVP-GVKIAGKTGTADV----ENGN 428
Cdd:TIGR03423 456 KPHLVKSIEDPDGGVVRRTEPEVLRPLpISPENLDVVREGMRDVVNGpgGTARRARLGlPYKMAGKTGTAQVvslkQGEK 535
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
4JBF_A 429 FN-----------SFFIGFAPYDHPTLVVSVVIEgNGenvlGYGAQVGG 466
Cdd:TIGR03423 536 YDaeqiperlrdhALFVAFAPYDNPKIAVAVIVE-HG----GGGSSAAA 579
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
125-456 |
8.53e-50 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 179.73 E-value: 8.53e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 125 LYS*AGINTTGSSVVLTINSQ*QAVAEAALQGY---------SGSIVV*DPSTGAVLAKASSPSYTHAELgtiiesgtgs 195
Cdd:COG0744 284 LLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVlpegkpgglQAALVVVDPKTGEVLAMVGGRDYGKSQF---------- 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 196 qlvDRTTQALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGT*EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGV 275
Cdd:COG0744 354 ---NRATQAKRQPGSTFKPFVYAAALEQGYTPATTVDDEPVTFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQ 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 276 ALGADNLVSYARAFGygtaLGQDFSTTPSL*PNPAE*TTWELAWAscglpvgeHASPAgpqttv*qnaviaaaiaNGGVV 355
Cdd:COG0744 431 EVGLDKVVDTARRLG----ITSPLDPNPSLALGTSEVSPLEMASA--------YATFA-----------------NGGVY 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 356 *NPYIVDRVLSPEGAVVSTTSPKSlGQAVSADTAAQVREA*LGVVESGTG*GARVPGVKIAGKTGTAdveNGNFNSFFIG 435
Cdd:COG0744 482 VEPHAITKVTDADGKVLYEAKPKC-EQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTT---NDNRDAWFVG 557
|
330 340
....*....|....*....|.
4JBF_A 436 FAPYdhptLVVSVVIeGNGEN 456
Cdd:COG0744 558 YTPQ----LVTAVWV-GNDDN 573
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
159-454 |
2.33e-42 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 152.19 E-value: 2.33e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 159 GSIVV*DPSTGAVLAKASSPSYThaelgtiiESGTGSQLVDRTTQALYSPGSSFKTVTLAAGIDTHKTTLDTTYSAPGT* 238
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYD--------PNGFIGPLRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 239 EIGGGTIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALGQDFSTTPSL*PNPAe*ttW-EL 317
Cdd:pfam00905 73 QQGGKSIGDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGENAGYLTPY----WlEG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 318 AWASCGLPVGehASP---AGPQTTv*qnaviaaaIANGGVV*NPYIVDRVlspegaVVSTTSPKSLGQAVSADTAAQVRE 394
Cdd:pfam00905 149 ATASFGIGLT--ITPlqqAQAYAA----------IANGGKLVPPHLVKSI------EDKVDPKVLNKLPISKSTAEKVKD 210
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
4JBF_A 395 A*LGVVESGTG*G-ARVPGVKIAGKTGTADV--------ENGNFNSFFIGFAPYDHPTLVVSVVIEGNG 454
Cdd:pfam00905 211 MLRLVVNDGTGTGtAAVPGYKVAGKTGTAQVagpkgggyYDGAQIGWFVGYAPADNPKYAFAVLIDDPK 279
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
93-468 |
3.37e-34 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 134.69 E-value: 3.37e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 93 GYISTQYGTAGIESS*NE---TLTGHADHSDW-----RSALYS*AG--INTTGSSVVLTINSQ*QAVAEAAL------QG 156
Cdd:TIGR02074 169 GYITAEEAEEAINEPIQLylqTKKSEQYKAPYfvdyvIQELEEEYGeeLYTGGLKIYTTLDLDAQKAAEKVLntglrvAG 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 157 YS------GSIVV*DPSTGAVLAKASSPSYThaelgtiiesgtGSQLvDRTTQALYSPGSSFKTVTLAAGIDTHKTTLDT 230
Cdd:TIGR02074 249 RRdgddlqAALVAIDPDTGAVRALVGGRDYG------------KSQF-NRATQAKRQPGSTFKPFVYAAALEKGLTPATI 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 231 TYSAPGT*EIGGG-TIHNYANED*GTIPLREAFARSSNTALAQLGVALGADNLVSYARAFGYGTALgqdfSTTPSL*PNP 309
Cdd:TIGR02074 316 VNDEPITYNGNGPwSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL----DPVLSLALGT 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 310 AE*TTWELAWAscglpvgeHASPAgpqttv*qnaviaaaiaNGGVV*NPYIVDRVLSPEGAVVSTTSPKSlGQAVSADTA 389
Cdd:TIGR02074 392 VEVSPLEMASA--------YAVFA-----------------NGGKYVEPHGIRKIVDRDGKVIYENKPKT-TQVISPATA 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 390 AQVREA*LGVVESGTG*GARVPGVKIAGKTGTADVengNFNSFFIGFAPYdhptlVVSVVIEGNGEN----VLGYGAQVG 465
Cdd:TIGR02074 446 YIMTDMLKGVVESGTGRSARLPGRPVAGKTGTTQN---WRDAWFVGYTPY-----YVTAVWVGYDDKktlgKSGTGGGLA 517
|
...
4JBF_A 466 GRV 468
Cdd:TIGR02074 518 API 520
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
158-468 |
3.10e-29 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 121.42 E-value: 3.10e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 158 SGSIVV*DPSTGAVLAKASSPSYTHaelgtiiesgtgSQLvDRTTQALYSPGSSFKTVTLAAGIDtHKTTLDTTYS-APG 236
Cdd:COG5009 422 QGALVALDPHTGAVLALVGGFDFEQ------------SKF-NRATQAKRQPGSSFKPFVYAAALD-NGYTPATIINdAPI 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 237 T*EIGGG----TIHNYANED*GTIPLREAFARSSNTA---LAQlgvALGADNLVSYARAFGYGTALGQDFS-------TT 302
Cdd:COG5009 488 VFDDGGGggvwRPKNYSGKFYGPTTLREALEKSRNLVtvrLLQ---DVGIDYVIDYAERFGIYSKLPPNLSlalgsgeVT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 303 Psl*pnpae*ttWELAWASCGLPvgehaspagpqttv*qnaviaaaiaNGGVV*NPYIVDRVLSPEGAVVSTTSPKSLG- 381
Cdd:COG5009 565 P-----------LEMARAYAVFA-------------------------NGGYRVEPYLIDRIEDRNGKVIYRADPARACe 608
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 382 -------------------QAVSADTAAQVREA*LGVVESGTG*GARVPGVKIAGKTGTAdveNGNFNSFFIGFAPYdhp 442
Cdd:COG5009 609 dcdaaewdgaeprlpdpaeQVIDPRTAYQMTSMLRGVVQRGTGRRARALGRDIAGKTGTT---NDSKDAWFVGFTPD--- 682
|
330 340
....*....|....*....|....*..
4JBF_A 443 tLVVSVVIeGNGENV-LGYGAQvGGRV 468
Cdd:COG5009 683 -LVAGVWV-GFDDPRsLGRGET-GGRA 706
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
80-465 |
8.53e-15 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 76.73 E-value: 8.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 80 RNYPHDG*ASHTVGYIST----------------------QYGTAGIESS*NETLTGHADhsdwrsalYS*AGINT---- 133
Cdd:PRK10795 165 RYYPYGSALTHVIGYVSKindkdverldkegklanyaathDIGKLGIERYYEDVLHGKTG--------YEEVEVNNrgrv 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 134 ----------TGSSVVLTINSQ*QAVAEAALQGYSGSIVV*DPSTGAVLAKASSPSYTHAELGTIIESGTGSQ------- 196
Cdd:PRK10795 237 irqlheqppqAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGILALVSTPSYDPNLFVDGISSKDYSGllndpnr 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 197 -LVDRTTQALYSPGSSFK----TVTLAAGIDTHKTTLdttySAPGT*EIGGGT--IHNYANED*GTIPLREAFARSSNTA 269
Cdd:PRK10795 317 pLINRATQGVYPPASTVKpyvaVSALSAGVITRNTSL----FDPGWWQLPGSEkrYRDWKKWGHGRLNVTKSLEESADTF 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 270 LAQLGVALGADNLVSYARAFGYGTALGQDFS-TTPSL*Pnpae*TTWELA------WASCGLPVGehaSPAGPQT-TV*Q 341
Cdd:PRK10795 393 FYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAeERSGNMP----TREWKQKrfkkpwYQGDTIPVG---IGQGYWTaTPIQ 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 342 NAVIAAAIANGGVV*NPYIVdRVLSPEGAVVSTTSPKS--LGQAVSA--DTAaqvREA*LGVVESGTG*G----ARVPgV 413
Cdd:PRK10795 466 MSKALMTLINDGIVKVPHLL-MSTAEDGKQVPWVQPHEppVGDIHSGywEIA---KDGMYGVANRPNGTAhkyfASAP-Y 540
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
4JBF_A 414 KIAGKTGTADV----ENGNFNS-----------FFIGFAPYDHPTLVVSVVIEgNGenvlGYGAQVG 465
Cdd:PRK10795 541 KIAAKSGTAQVfglkANETYNAhkiaerlrdhkLMTAFAPYNNPQVAVAIILE-NG----GAGPAVG 602
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
65-450 |
5.57e-12 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 67.92 E-value: 5.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 65 VTLAESVKQDDGTYV---------------RNYPHDG*ASHTVGY--ISTQyGTAGIESS*NETLTGHADHSDWRSALYS 127
Cdd:PRK15105 136 IYLARQVNPDMADYIkklklpgihlreesrRYYPSGEVTAHLIGFtnVDSQ-GIEGVEKSFDKWLTGQPGERIVRKDRYG 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 128 *A--GINTTGS----SVVLTINSQ*QAV-------AEAALQGYSGSIVV*DPSTGAVLAKASSPSYTHAELgtiieSGTG 194
Cdd:PRK15105 215 RVieDISSTDSqaahNLALSIDERLQALvyrelnnAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNL-----SGTP 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 195 SQLV-DRTTQALYSPGSSFK-TVTLAA---GIDTHKTTLDTTysapgT*EIGGGTIHNYANED*GTIPlrEAFARSSNTA 269
Cdd:PRK15105 290 KDAMrNRAITDVFEPGSTVKpMVVMTAlqrGVVKENSVLNTV-----PYRINGHEIKDVARYSELTLT--GVLQKSSNVG 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 270 LAQLGVALGADNLV-SYARaFGYG--TALGQdFSTTPSL*PNPAE*TTWELAWASCGLpvgehaspagpqttv*qnavia 346
Cdd:PRK15105 363 VSKLALAMPSSALVdTYSR-FGLGkaTNLGL-VGERSGLYPQKQRWSDIERATFSFGY---------------------- 418
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 347 aaiangGVV*NPYIVDRVLSPEGAV-------VSTTSPKSLGQAVSADtaaQVREA*LGVVES-----GTG*GARVPGVK 414
Cdd:PRK15105 419 ------GLMVTPLQLARVYATIGSYgiyrplsITKVDPPVPGERVFPE---SIVRTVVHMMESvalpgGGGVKAAIKGYR 489
|
410 420 430 440
....*....|....*....|....*....|....*....|..
4JBF_A 415 IAGKTGTADV--ENGNFNSFFI----GFAPYDHPTLVVSVVI 450
Cdd:PRK15105 490 IAIKTGTAKKvgPDGRYINKYIaytaGVAPASQPRFALVVVI 531
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
132-435 |
8.72e-06 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 48.23 E-value: 8.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 132 NTTGSSVVLTINSQ*QAVAEAA-------------LQGYSGSIVV*DPSTGAVLAK--ASSPSYthaelgtiieSGtgsq 196
Cdd:PRK09506 430 DLSGVKIFTTLDPVSQDAAEKAveegipalkkqrkLSDLETAMVVVDRFSGEVRAMvgGSEPQF----------AG---- 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 197 lVDRTTQALYSPGSSFKTVT-LAAGIDTHKTTLDTTYS-APGT*EIGGGTI---HNYANED*GTIPLREAFARSSNTALA 271
Cdd:PRK09506 496 -YNRAMQARRSIGSLAKPATyLTALSQPDKYRLNTWIAdAPISLRQPNGQVwspQNDDRRFSGRVMLVDALTRSMNVPTV 574
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 272 QLGVALGADNLVSYARAFGYGTALGQDFsttPSL*PNPAE*TTWELAWAScglpvgehaspagpQTTV*qnaviaaaian 351
Cdd:PRK09506 575 NLGMALGLPAVTDTWIKLGVPKDQLNPV---PAMLLGALNLTPIEVAQAF--------------QTIAS----------- 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 352 GGVV*NPYIVDRVLSPEGAVVSTTSPKSlGQAVSADTAAQVREA*LGVVESGTG*--GARVPGVKIAGKTGTAdveNGNF 429
Cdd:PRK09506 627 GGNRAPLSALRSVIAEDGKVLYQSFPQA-ERAVPAQAAYLTLYTMQQVVQRGTGRqlGAKYPNLHLAGKTGTT---NDLV 702
|
....*.
4JBF_A 430 NSFFIG 435
Cdd:PRK09506 703 DSWFAG 708
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
132-421 |
4.92e-05 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 45.98 E-value: 4.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 132 NTTGSSVVLTINSQ*QAVAEAALQGY----------SGSIVV*DPSTGAVLAKASSPSYTHAELgtiiesgtGSQlVDrT 201
Cdd:COG4953 268 LPGGTRIRTTLDAGLQRRLERLVRRYvrrlkqngihNAAVLVVDNRTGEVLAYVGSADFFDASR--------QGQ-VD-M 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 202 TQALYSPGSsfktvTL-----AAGID---THKTTL--DTtysaPgt*EIGGGTIHNYANED*GTIPLREAFARSSN---- 267
Cdd:COG4953 338 VRALRSPGS-----TLkpflyGLALDqglIHPETLlaDV----P--TSFGGYRPENFDGTFQGPVSAREALARSLNipav 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 268 TALAQLGVA--------LGADNLVSYARAFGYGTALGQdfsttpsl*pnpAE*TTWEL-----AWASCGLPVGEHASPAG 334
Cdd:COG4953 407 RLLEALGPArfyarlrrAGLRLLLPPAEHYGLSLILGG------------AEVTLEELvglyaALARGGEARPLRLLAGE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4JBF_A 335 PQTTV*qnaviaaaianggvv*npyivdRVLSPEgavvsttspkslgqavsadTAAQVREA*LGVV--ESGTG*GARVPG 412
Cdd:COG4953 475 PASPGR----------------------RLLSPG-------------------AAWLVRDILSDVPrpDGAFGWRALDSP 513
|
....*....
4JBF_A 413 VKIAGKTGT 421
Cdd:COG4953 514 PPIAWKTGT 522
|
|
| PBP_dimer |
pfam03717 |
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ... |
79-115 |
3.16e-03 |
|
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain] Cd Length: 178 Bit Score: 38.46 E-value: 3.16e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
4JBF_A 79 VRNYPHDG*ASHTVGYIS------------TQY------GTAGIESS*NETLTGH 115
Cdd:pfam03717 107 VRYYPYGELAAHLLGYVGeiteeelekyldKGYsrgdlvGKSGLEKQYESVLRGK 161
|
|
| |
