NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|550544367|pdb|4BJN|F]
View 

Chain F, AVRM-A

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AvrM-A super family cl39595
Flax-rust effector AvrM-A; This domain is found in AvrM-A present in Melampsora lini. AvrM-A ...
 95-241 1.53e-28

Flax-rust effector AvrM-A; This domain is found in AvrM-A present in Melampsora lini. AvrM-A is a natural variant of AvrM which is a secreted effector protein that can internalize into plant cells in the absence of the pathogen and bind to phosphoinositides. AvrM results in effector-triggered immunity. This domain makes up part of the C-terminal region, which is highly conserved in AvrM. The domain is required for M-dependent effector-triggered immunity.


The actual alignment was detected with superfamily member pfam18241:

Pssm-ID: 408062  Cd Length: 147  Bit Score: 105.38  E-value: 1.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4BJN_F         95 ESLTRDALLKLTEEQYVEKAALFDKDVYRNNLKRQTYEKLLRSETDVLYREVARIFIAREGEPALTAKIERLALTLENNA 174
Cdd:pfam18241   1 ESLTPQALSKLTDKEYVRKAALFDQKVQQNLAQWEAQEKLLHDYLSKLYKLQLLEFKKSKGEKKLKAKITKIMEKLKEKA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
4BJN_F        175 DTRSKPIDYLAIAADFLKNQANLHADDPELNLYKAEIKAREIEANRAMKEALKGADKLFKRNKILKS 241
Cdd:pfam18241  81 KAKGKPIDEKAAQRQFIKEQAKLHPKDPEWKEDEETIKEFEKYVRNAKNKALRSADRVYKRNKLLKS 147
AvrM_N super family cl39600
Flax-rust effector AvrM N-terminal domain; This is the N-terminal domain found in AvrM present ...
 10-63 1.58e-12

Flax-rust effector AvrM N-terminal domain; This is the N-terminal domain found in AvrM present in Melampsora lini. AvrM is a secreted effector protein that can internalize into plant cells in the absence of pathogens, binds to phosphoinositides and results in effector-triggered immunity. This domain is related to the WY domain core in oomycete effectors.


The actual alignment was detected with superfamily member pfam18247:

Pssm-ID: 375674  Cd Length: 65  Bit Score: 60.96  E-value: 1.58e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
4BJN_F         10 PEFDRGFLRPFGAKMKFLKPDQVQKLSTDDLITYMAEKDKNVRDLAIKLRDAKQ 63
Cdd:pfam18247   2 PIFKRAHGKPFGETMEFLKPDEVEKLSPDELIRYMAERDTNVQKMARKLYKAAQ 55
 
Name Accession Description Interval E-value
AvrM-A pfam18241
Flax-rust effector AvrM-A; This domain is found in AvrM-A present in Melampsora lini. AvrM-A ...
 95-241 1.53e-28

Flax-rust effector AvrM-A; This domain is found in AvrM-A present in Melampsora lini. AvrM-A is a natural variant of AvrM which is a secreted effector protein that can internalize into plant cells in the absence of the pathogen and bind to phosphoinositides. AvrM results in effector-triggered immunity. This domain makes up part of the C-terminal region, which is highly conserved in AvrM. The domain is required for M-dependent effector-triggered immunity.


Pssm-ID: 408062  Cd Length: 147  Bit Score: 105.38  E-value: 1.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4BJN_F         95 ESLTRDALLKLTEEQYVEKAALFDKDVYRNNLKRQTYEKLLRSETDVLYREVARIFIAREGEPALTAKIERLALTLENNA 174
Cdd:pfam18241   1 ESLTPQALSKLTDKEYVRKAALFDQKVQQNLAQWEAQEKLLHDYLSKLYKLQLLEFKKSKGEKKLKAKITKIMEKLKEKA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
4BJN_F        175 DTRSKPIDYLAIAADFLKNQANLHADDPELNLYKAEIKAREIEANRAMKEALKGADKLFKRNKILKS 241
Cdd:pfam18241  81 KAKGKPIDEKAAQRQFIKEQAKLHPKDPEWKEDEETIKEFEKYVRNAKNKALRSADRVYKRNKLLKS 147
AvrM_N pfam18247
Flax-rust effector AvrM N-terminal domain; This is the N-terminal domain found in AvrM present ...
 10-63 1.58e-12

Flax-rust effector AvrM N-terminal domain; This is the N-terminal domain found in AvrM present in Melampsora lini. AvrM is a secreted effector protein that can internalize into plant cells in the absence of pathogens, binds to phosphoinositides and results in effector-triggered immunity. This domain is related to the WY domain core in oomycete effectors.


Pssm-ID: 375674  Cd Length: 65  Bit Score: 60.96  E-value: 1.58e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
4BJN_F         10 PEFDRGFLRPFGAKMKFLKPDQVQKLSTDDLITYMAEKDKNVRDLAIKLRDAKQ 63
Cdd:pfam18247   2 PIFKRAHGKPFGETMEFLKPDEVEKLSPDELIRYMAERDTNVQKMARKLYKAAQ 55
 
Name Accession Description Interval E-value
AvrM-A pfam18241
Flax-rust effector AvrM-A; This domain is found in AvrM-A present in Melampsora lini. AvrM-A ...
 95-241 1.53e-28

Flax-rust effector AvrM-A; This domain is found in AvrM-A present in Melampsora lini. AvrM-A is a natural variant of AvrM which is a secreted effector protein that can internalize into plant cells in the absence of the pathogen and bind to phosphoinositides. AvrM results in effector-triggered immunity. This domain makes up part of the C-terminal region, which is highly conserved in AvrM. The domain is required for M-dependent effector-triggered immunity.


Pssm-ID: 408062  Cd Length: 147  Bit Score: 105.38  E-value: 1.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4BJN_F         95 ESLTRDALLKLTEEQYVEKAALFDKDVYRNNLKRQTYEKLLRSETDVLYREVARIFIAREGEPALTAKIERLALTLENNA 174
Cdd:pfam18241   1 ESLTPQALSKLTDKEYVRKAALFDQKVQQNLAQWEAQEKLLHDYLSKLYKLQLLEFKKSKGEKKLKAKITKIMEKLKEKA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
4BJN_F        175 DTRSKPIDYLAIAADFLKNQANLHADDPELNLYKAEIKAREIEANRAMKEALKGADKLFKRNKILKS 241
Cdd:pfam18241  81 KAKGKPIDEKAAQRQFIKEQAKLHPKDPEWKEDEETIKEFEKYVRNAKNKALRSADRVYKRNKLLKS 147
AvrM_N pfam18247
Flax-rust effector AvrM N-terminal domain; This is the N-terminal domain found in AvrM present ...
 10-63 1.58e-12

Flax-rust effector AvrM N-terminal domain; This is the N-terminal domain found in AvrM present in Melampsora lini. AvrM is a secreted effector protein that can internalize into plant cells in the absence of pathogens, binds to phosphoinositides and results in effector-triggered immunity. This domain is related to the WY domain core in oomycete effectors.


Pssm-ID: 375674  Cd Length: 65  Bit Score: 60.96  E-value: 1.58e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
4BJN_F         10 PEFDRGFLRPFGAKMKFLKPDQVQKLSTDDLITYMAEKDKNVRDLAIKLRDAKQ 63
Cdd:pfam18247   2 PIFKRAHGKPFGETMEFLKPDEVEKLSPDELIRYMAERDTNVQKMARKLYKAAQ 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH