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Conserved domains on  [gi|269914676|pdb|3KQF|C]
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Chain C, Enoyl-CoA hydratase/isomerase family protein

Protein Classification

Clp protease/crotonase-like domain-containing protein; enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10792970)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate| enoyl-CoA hydratase/isomerase family protein similar to enoyl-CoA hydratase, which catalyzes the second step in the beta-oxidation pathway of fatty acid metabolism, the syn-addition of a water molecule across the double bond of a trans-2-enoyl-CoA thioester, resulting in the formation of a beta-hydroxyacyl-CoA thioester

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
6-265 7.19e-163

enoyl-CoA hydratase; Provisional


:

Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 451.88  E-value: 7.19e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         6 QLQNISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVR 85
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        86 HAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 165
Cdd:PRK07657  81 HAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       166 LIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTK 245
Cdd:PRK07657 161 LIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTK 240
                        250       260
                 ....*....|....*....|
3KQF_C       246 DRLEGLQAFKEKRTP*YKGE 265
Cdd:PRK07657 241 DRLEGLQAFKEKRKPMYKGE 260
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
6-265 7.19e-163

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 451.88  E-value: 7.19e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         6 QLQNISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVR 85
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        86 HAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 165
Cdd:PRK07657  81 HAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       166 LIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTK 245
Cdd:PRK07657 161 LIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTK 240
                        250       260
                 ....*....|....*....|
3KQF_C       246 DRLEGLQAFKEKRTP*YKGE 265
Cdd:PRK07657 241 DRLEGLQAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
18-258 7.21e-87

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 258.56  E-value: 7.21e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE-RAG*NEEQVRHAVS*IRTT*E 96
Cdd:COG1024   8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       97 *VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQ 176
Cdd:COG1024  87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C      177 EAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKE 256
Cdd:COG1024 167 EALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLE 246

                ..
3KQF_C      257 KR 258
Cdd:COG1024 247 KR 248
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-264 1.38e-65

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 204.52  E-value: 1.38e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGaGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*V 98
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         99 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 178
Cdd:pfam00378  85 YTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEA 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        179 KEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKR 258
Cdd:pfam00378 165 LKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKR 244

                  ....*.
3KQF_C        259 TP*YKG 264
Cdd:pfam00378 245 KPPWED 250
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
18-204 9.90e-65

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 200.48  E-value: 9.90e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE--RAG*NEEQVRHAVS*IRTT* 95
Cdd:cd06558   8 GVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKElaALSDAGEEARAFIRELQELL 86
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       96 E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 175
Cdd:cd06558  87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISA 166
                       170       180
                ....*....|....*....|....*....
3KQF_C      176 QEAKEYGLVEFVVPVHLLEEKAIEIAEKI 204
Cdd:cd06558 167 EEALELGLVDEVVPDEELLAAALELARRL 195
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
47-238 2.42e-30

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 119.17  E-value: 2.42e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         47 QINEEANTRVVILTGAGekAFCAGADLK----ERAG*NEEQVRHAVS*Irtt*E*VEQLPQPVIAAINGIALGGGTELSL 122
Cdd:TIGR02441  54 WTNEAIKSAVLISGKPG--SFVAGADIQmiaaCKTAQEVTQLSQEGQEM---FERIEKSQKPIVAAISGSCLGGGLELAL 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        123 ACDFRIAAESAS--LGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVP-----VHLLEE 195
Cdd:TIGR02441 129 ACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVDplgpgLKPAEE 208
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
3KQF_C        196 KAIEIAEKiasngpIAVRLAKEAISNGIQVDLHTGLQ*EKQAY 238
Cdd:TIGR02441 209 NTIEYLEE------VAVKFAQGLANGKLSINRDKGLVHKITQY 245
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
6-265 7.19e-163

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 451.88  E-value: 7.19e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         6 QLQNISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVR 85
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        86 HAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 165
Cdd:PRK07657  81 HAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       166 LIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTK 245
Cdd:PRK07657 161 LIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTK 240
                        250       260
                 ....*....|....*....|
3KQF_C       246 DRLEGLQAFKEKRTP*YKGE 265
Cdd:PRK07657 241 DRLEGLQAFKEKRKPMYKGE 260
PLN02600 PLN02600
enoyl-CoA hydratase
19-265 7.00e-92

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 271.68  E-value: 7.00e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*V 98
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        99 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 178
Cdd:PLN02600  85 EALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       179 KEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKR 258
Cdd:PLN02600 165 ASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKR 244

                 ....*..
3KQF_C       259 TP*YKGE 265
Cdd:PLN02600 245 KPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
18-258 7.21e-87

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 258.56  E-value: 7.21e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE-RAG*NEEQVRHAVS*IRTT*E 96
Cdd:COG1024   8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       97 *VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQ 176
Cdd:COG1024  87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C      177 EAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKE 256
Cdd:COG1024 167 EALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLE 246

                ..
3KQF_C      257 KR 258
Cdd:COG1024 247 KR 248
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
18-264 2.77e-75

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 229.63  E-value: 2.77e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E* 97
Cdd:PRK05809  13 HIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVFRK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 177
Cdd:PRK05809  93 LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEE 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       178 AKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEK 257
Cdd:PRK05809 173 ALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFVEK 252

                 ....*..
3KQF_C       258 RTP*YKG 264
Cdd:PRK05809 253 REKNFKN 259
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
18-265 2.68e-68

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 211.80  E-value: 2.68e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRErQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NE-EQVRHAVS*IRTT*E 96
Cdd:PRK07658  11 HVAVITLNHP-PANALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFTSVTEaEQATELAQLGQVTFE 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        97 *VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQ 176
Cdd:PRK07658  89 RVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITGA 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       177 EAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKE 256
Cdd:PRK07658 169 EALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFLE 248

                 ....*....
3KQF_C       257 KRTP*YKGE 265
Cdd:PRK07658 249 KRKPSFSGK 257
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-264 1.38e-65

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 204.52  E-value: 1.38e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGaGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*V 98
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         99 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 178
Cdd:pfam00378  85 YTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEA 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        179 KEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKR 258
Cdd:pfam00378 165 LKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKR 244

                  ....*.
3KQF_C        259 TP*YKG 264
Cdd:pfam00378 245 KPPWED 250
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
45-264 2.74e-65

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 203.95  E-value: 2.74e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGeKAFCAGADLKE---RAG*NEEQVRHAVS*IRtt*e*VEQLPQPVIAAINGIALGGGTELS 121
Cdd:PRK06688  41 LEAAATDPAVRVVVLTGAG-RAFSAGGDIKDfpkAPPKPPDELAPVNRFLR----AIAALPKPVVAAVNGPAVGVGVSLA 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       122 LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIA 201
Cdd:PRK06688 116 LACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQA 195
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
3KQF_C       202 EKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06688 196 AKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFIEKRKPDFTG 258
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
18-204 9.90e-65

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 200.48  E-value: 9.90e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE--RAG*NEEQVRHAVS*IRTT* 95
Cdd:cd06558   8 GVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKElaALSDAGEEARAFIRELQELL 86
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       96 E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 175
Cdd:cd06558  87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISA 166
                       170       180
                ....*....|....*....|....*....
3KQF_C      176 QEAKEYGLVEFVVPVHLLEEKAIEIAEKI 204
Cdd:cd06558 167 EEALELGLVDEVVPDEELLAAALELARRL 195
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
18-264 3.00e-63

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 199.11  E-value: 3.00e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQV----------RHA 87
Cdd:PRK06494  13 HVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWpesgfggltsRFD 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        88 vs*irtt*e*veqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 167
Cdd:PRK06494  93 -------------LDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       168 YTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQ--AYEGVIHTK 245
Cdd:PRK06494 160 LTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDypAVEARRASQ 239
                        250
                 ....*....|....*....
3KQF_C       246 DRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06494 240 DYIEGPKAFAEKRPPRWKG 258
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
19-264 2.76e-62

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 196.53  E-value: 2.76e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAgEKAFCAGADLKERAg*nEEQVRHAVS*IRTT*-E* 97
Cdd:PRK09674  12 VLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMA---EKDLAATLNDPRPQLwQR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 177
Cdd:PRK09674  88 LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQ 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       178 AKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEK 257
Cdd:PRK09674 168 AQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAFLEK 247

                 ....*..
3KQF_C       258 RTP*YKG 264
Cdd:PRK09674 248 RTPDFKG 254
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
10-265 6.30e-59

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 187.95  E-value: 6.30e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        10 ISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGaGEKAFCAGADLKE--RAG*NEEQVRHA 87
Cdd:PRK08138   9 VLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEfaTAGAIEMYLRHT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        88 vs*iRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 167
Cdd:PRK08138  88 ----ERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMA 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       168 YTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDR 247
Cdd:PRK08138 164 LTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQ 243
                        250
                 ....*....|....*...
3KQF_C       248 LEGLQAFKEKRTP*YKGE 265
Cdd:PRK08138 244 KEGMDAFLEKRKPAYKGK 261
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
18-263 2.58e-58

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 186.28  E-value: 2.58e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRErQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E* 97
Cdd:PRK09076  12 HVAILTLNNP-PANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFGEAFEA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 177
Cdd:PRK09076  91 LSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAAT 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       178 AKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEK 257
Cdd:PRK09076 171 ALRIGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLEK 250

                 ....*.
3KQF_C       258 RTP*YK 263
Cdd:PRK09076 251 RAPQWK 256
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
22-263 2.92e-58

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 186.02  E-value: 2.92e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        22 ISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAgEKAFCAGADLKERAG*NEEQVrhAVS*IRTT*E*VEQL 101
Cdd:PRK05862  17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIKEMADLSFMDV--YKGDYITNWEKVARI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       102 PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEY 181
Cdd:PRK05862  94 RKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERA 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       182 GLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKRTP* 261
Cdd:PRK05862 174 GLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRKPV 253

                 ..
3KQF_C       262 YK 263
Cdd:PRK05862 254 FK 255
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
18-265 2.13e-57

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 184.13  E-value: 2.13e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERqANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E* 97
Cdd:PRK03580  12 SILEITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTE- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 177
Cdd:PRK03580  90 IFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       178 AKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EK----QAYEGVIHTKDRLEGLQA 253
Cdd:PRK03580 170 ALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRsgvlKHYPSVLHSEDALEGPRA 249
                        250
                 ....*....|..
3KQF_C       254 FKEKRTP*YKGE 265
Cdd:PRK03580 250 FAEKRDPVWKGR 261
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
18-265 4.41e-56

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 180.94  E-value: 4.41e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEEL-QNILTQINEEANTRVVILTGAGeKAFCAGADLK---ERAG*NE-------EQVRH 86
Cdd:PRK09245  12 HIVTLTMNRPETRNALSDNDAVDAlVAACAAINADRSVRAVILTGAG-TAFSSGGNVKdmrARVGAFGgspadirQGYRH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        87 AVS*Irtt*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL 166
Cdd:PRK09245  91 GIQRI---PLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEM 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       167 IYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKqAYEGVIH-TK 245
Cdd:PRK09245 168 AFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSA-AYQALAHhTA 246
                        250       260
                 ....*....|....*....|
3KQF_C       246 DRLEGLQAFKEKRTP*YKGE 265
Cdd:PRK09245 247 DHREAVDAFLEKRPPVFTGR 266
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
19-262 1.13e-52

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 171.86  E-value: 1.13e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVRHA----VS*IRTT 94
Cdd:PRK05980  13 IALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVAlrdfVRRGQAM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        95 *E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 174
Cdd:PRK05980  93 TARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAFS 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       175 AQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAF 254
Cdd:PRK05980 173 AERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLREGLAAW 252

                 ....*...
3KQF_C       255 KEKRTP*Y 262
Cdd:PRK05980 253 IERRRPAY 260
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
18-265 1.36e-50

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 166.82  E-value: 1.36e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NE-EQVR---HAVS*IRT 93
Cdd:PRK07799  14 HTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAG-GAFCAGMDLKAATKKPPgDSFKdgsYDPSRIDA 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        94 T*E*vEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 173
Cdd:PRK07799  93 LLKG-RRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHI 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       174 SAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQA 253
Cdd:PRK07799 172 TAAEAKEIGLIGHVVPDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRA 251
                        250
                 ....*....|..
3KQF_C       254 FKEKRTP*YKGE 265
Cdd:PRK07799 252 FAEKRAPNFQGR 263
PLN02888 PLN02888
enoyl-CoA hydratase
10-259 1.44e-47

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 158.76  E-value: 1.44e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        10 ISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLkerag*NEEQVRHAVS 89
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG-RAFCSGVDL-----TAAEEVFKGDV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        90 *IRTT*E*V--EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 167
Cdd:PLN02888  85 KDVETDPVAqmERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVS 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       168 YTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQA----YEGVih 243
Cdd:PLN02888 165 LTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKERahdyYNGM-- 242
                        250
                 ....*....|....*.
3KQF_C       244 TKDRLEGLQAFKEKRT 259
Cdd:PLN02888 243 TKEQFQKMQEFIAGRS 258
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
44-264 4.59e-47

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 157.56  E-value: 4.59e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        44 ILTQINEEANTRVVILTGAGEKAFCAGADLKERag*neEQVRHAVS*IRTT*E*VEQ-------LPQPVIAAINGIALGG 116
Cdd:PRK06127  46 ALAAAEDDDAIRVVVLTGAGEKAFVSGADISQF-----EESRSDAEAVAAYEQAVEAaqaaladYAKPTIACIRGYCIGG 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       117 GTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEK 196
Cdd:PRK06127 121 GMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIGLVHRVTAADDLETA 200
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3KQF_C       197 AIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06127 201 LADYAATIAGNAPLTLRAAKRAIAELLKDEPERDMAACQALVAACFDSEDYREGRAAFMEKRKPVFKG 268
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
16-237 1.35e-46

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 156.29  E-value: 1.35e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        16 TPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*nEEQVRHAVS*IRTT* 95
Cdd:PRK06190  11 HDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGAD-PAFCAGLDLKELGG--DGSAYGAQDALPNPS 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        96 E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 175
Cdd:PRK06190  88 PAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDA 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
3KQF_C       176 QEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQA 237
Cdd:PRK06190 168 ADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEA 229
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
22-265 2.70e-44

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 150.14  E-value: 2.70e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        22 ISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLK-----ER--------AG*NEEQVRhav 88
Cdd:PRK08252  16 ITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAG-GTFCAGMDLKafargERpsipgrgfGGLTERPPR--- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        89 s*irtt*e*veqlpQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIY 168
Cdd:PRK08252  92 --------------KPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       169 TGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRL 248
Cdd:PRK08252 158 TGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAK 237
                        250
                 ....*....|....*..
3KQF_C       249 EGLQAFKEKRTP*YKGE 265
Cdd:PRK08252 238 EGATAFAEKRAPVWTGK 254
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
44-264 1.27e-43

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 148.30  E-value: 1.27e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        44 ILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQ-VRHAVS*I-RTT*E*VEQLPQPVIAAINGIALGGGTELS 121
Cdd:PRK06495  38 VFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKGPgDLRAHNRRtRECFHAIRECAKPVIAAVNGPALGAGLGLV 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       122 LACDFRIAAESASLGLTETTLAIipgAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIA 201
Cdd:PRK06495 117 ASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHSLTRRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIA 193
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
3KQF_C       202 EKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06495 194 REIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTEDAKEAQRAFLEKRPPVFKG 256
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
45-225 1.97e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 145.18  E-value: 1.97e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLAC 124
Cdd:PRK06143  43 LRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAAC 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       125 DFRIAAESASLGLTETTLAiIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKI 204
Cdd:PRK06143 123 DLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTGETIDAAQALAWGLVDRVVPLAELDAAVERLAASL 201
                        170       180       190
                 ....*....|....*....|....*....|...
3KQF_C       205 ASNGPIAVRLAK------------EAISNGIQV 225
Cdd:PRK06143 202 AGCGPQALRQQKrllrewedmpldVAIDDSVAE 234
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
6-264 6.44e-42

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 144.35  E-value: 6.44e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         6 QLQNISVDYATpHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADL-----------K 74
Cdd:PRK06142   4 TYESFTVELAD-HVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSG-KHFSYGIDLpamagvfgqlgK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        75 ERAG*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRL 154
Cdd:PRK06142  82 DGLARPRTDLRREILRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       155 PRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVH--LLEEkAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ 232
Cdd:PRK06142 162 PRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVYDDAdaLLAA-AHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLR 240
                        250       260       270
                 ....*....|....*....|....*....|..
3KQF_C       233 *EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06142 241 YVATWNAAMLPSKDLTEAIAAHMEKRPPEFTG 272
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
18-265 7.15e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 143.90  E-value: 7.15e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQInEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQVRHAVS*IRT---- 93
Cdd:PRK08140  13 GVATLTLNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAG-RGFCAGQDLADRDVTPGGAMPDLGESIETfynp 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        94 T*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 173
Cdd:PRK08140  91 LVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGEKL 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       174 SAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQA 253
Cdd:PRK08140 171 SAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADYAEGVSA 250
                        250
                 ....*....|..
3KQF_C       254 FKEKRTP*YKGE 265
Cdd:PRK08140 251 FLEKRAPRFTGR 262
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
18-264 4.21e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 143.22  E-value: 4.21e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADL---------KERAG*NEEQVR--- 85
Cdd:PRK08260  13 GIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLsaggntfdlDAPRTPVEADEEdra 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        86 -HAVS*IRTT----*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGV 160
Cdd:PRK08260  92 dPSDDGVRDGggrvTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGL 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       161 GRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASN-GPIAVRLAKEAISNGIQVD----LHtglQ*EK 235
Cdd:PRK08260 172 QTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNtSPVSVALTRQMMWRMAGADhpmeAH---RVDS 248
                        250       260
                 ....*....|....*....|....*....
3KQF_C       236 QAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK08260 249 RAIYSRGRSGDGKEGVSSFLEKRPAVFPG 277
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
48-264 9.70e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 141.28  E-value: 9.70e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        48 INEEANTRVVILTGAGEKAFCAGADLKE-RAG*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDF 126
Cdd:PRK06144  47 IAADPSIRAVVLRGAGDKAFVAGTDIAQfRAFSTAEDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDL 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       127 RIAAESASLGL-TETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIA 205
Cdd:PRK06144 127 RIATPSARFGFpIARTLGNCLSMSNLARLVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLA 206
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
3KQF_C       206 SNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYegviHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06144 207 AHAPLTLRATKEALRRLRREGLPDGDDLIRMCY----MSEDFREGVEAFLEKRPPKWKG 261
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
18-263 9.73e-41

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 141.17  E-value: 9.73e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E* 97
Cdd:PRK07509  12 GIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEG-GAFCAGLDVKSVASSPGNAVKLLFKRLPGNANL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VEQ-------LPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTG 170
Cdd:PRK07509  91 AQRvslgwrrLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       171 RRISAQEAKEYGLVEFVVPVHLleEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEG 250
Cdd:PRK07509 171 RVFSAEEALELGLVTHVSDDPL--AAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLLGKNQKIA 248
                        250
                 ....*....|...
3KQF_C       251 LQAFKEKRTP*YK 263
Cdd:PRK07509 249 VKAQMKKRAPKFL 261
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
21-263 1.63e-39

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 138.10  E-value: 1.63e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        21 KISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKER--AG-*NEEQV-RHAV----S*IR 92
Cdd:PRK07396  25 KITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRgyGGyVDDDGVpRLNVldlqRLIR 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        93 Tt*e*veqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRR 172
Cdd:PRK07396 105 T-------CPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQ 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       173 ISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISngIQVDLHTGLQ*-EKQAYEGVIHTKDRLEGL 251
Cdd:PRK07396 178 YDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALN--ADCDGQAGLQElAGNATMLFYMTEEAQEGR 255
                        250
                 ....*....|..
3KQF_C       252 QAFKEKRTP*YK 263
Cdd:PRK07396 256 NAFNEKRQPDFS 267
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
19-262 2.02e-39

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 138.11  E-value: 2.02e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLK------ERA-----G*NEEQVRHA 87
Cdd:PLN02664  18 VFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKtlnsisEQSssgdrGRSGERLRRK 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        88 VS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 167
Cdd:PLN02664  97 IKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       168 YTGRRISAQEAKEYGLVEFVV-PVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKD 246
Cdd:PLN02664 177 LTGRRFSGSEAKELGLVSRVFgSKEDLDEGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDD 256
                        250
                 ....*....|....*.
3KQF_C       247 RLEGLQAFKEKRTP*Y 262
Cdd:PLN02664 257 LNEAVSAQIQKRKPVF 272
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
19-265 2.28e-39

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 137.77  E-value: 2.28e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE-RAG*NEEQVRHAVS*IRTT*E* 97
Cdd:PRK08139  21 VATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAG-KAFCAGHDLKEmRAARGLAYFRALFARCSRVMQA 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESAS-------LGLTETTlaiiPGAGGTQRLPRligvGRAKELIYTG 170
Cdd:PRK08139 100 IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARfavpgvnIGLFCST----PMVALSRNVPR----KQAMEMLLTG 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       171 RRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLhtglq*EKQAYEGVIHTK----- 245
Cdd:PRK08139 172 EFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFYRQAEMPL-----ADAYAYAGDVMAEnmmae 246
                        250       260
                 ....*....|....*....|
3KQF_C       246 DRLEGLQAFKEKRTP*YKGE 265
Cdd:PRK08139 247 DAEEGIDAFLEKRPPEWRGR 266
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
17-265 3.37e-39

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 136.98  E-value: 3.37e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        17 PHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADL---KERAG*NEEQVRHAVS*IRT 93
Cdd:PRK05995  12 GQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDENRADARRLAD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        94 T*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPgaggTQRLP---RLIGVGRAKELIYTG 170
Cdd:PRK05995  91 MLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLTA 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       171 RRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISN--GIQVDLHTGLQ*EKQAyeGVIH-TKDR 247
Cdd:PRK05995 167 ERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLVRDvaGRPIDAALIADTASRI--ALIRaTEEA 244
                        250
                 ....*....|....*...
3KQF_C       248 LEGLQAFKEKRTP*YKGE 265
Cdd:PRK05995 245 REGVAAFLEKRKPAWRGR 262
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
45-210 3.14e-38

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 141.92  E-value: 3.14e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTgAGEKAFCAGADLKERAG---*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELS 121
Cdd:PRK11730  43 LDALEAQSDLKGLLLT-SAKDAFIVGADITEFLSlfaAPEEELSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECV 121
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       122 LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIA 201
Cdd:PRK11730 122 LATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAALALL 201

                 ....*....
3KQF_C       202 eKIASNGPI 210
Cdd:PRK11730 202 -KQAIAGKL 209
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
44-203 4.29e-38

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 141.19  E-value: 4.29e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        44 ILTQINEEANTRVVILTGAGEKAFCAGADLKERAG-*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSL 122
Cdd:PRK11154  42 ILKQLREDKELKGVVFISGKPDNFIAGADINMLAAcKTAQEAEALARQGQQLFAEIEALPIPVVAAIHGACLGGGLELAL 121
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       123 ACDFRIAAESA--SLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEI 200
Cdd:PRK11154 122 ACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVEL 201

                 ...
3KQF_C       201 AEK 203
Cdd:PRK11154 202 AKK 204
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
8-264 4.93e-38

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 134.45  E-value: 4.93e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         8 QNISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQVRHA 87
Cdd:PRK06210   5 DAVLYEVADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAG-RGFCAGADMGELQTIDPSDGRRD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        88 VS----------*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRL 157
Cdd:PRK06210  84 TDvrpfvgnrrpDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRL 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       158 IGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASN-GPIAVRLAKEAISNGIQVDLHTGLQ*EKQ 236
Cdd:PRK06210 164 VGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNvSPASMAVIKRQLYEDAFQTLAEATARANR 243
                        250       260
                 ....*....|....*....|....*...
3KQF_C       237 AYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK06210 244 EMHESLQRPDFIEGVASFLEKRPPRFPG 271
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
13-264 3.11e-37

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 132.40  E-value: 3.11e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        13 DYATPH--------VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEkAFCAGADLKERAG*neEQV 84
Cdd:PRK08258  13 GYEARHflwevddgVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGG-NFCSGGDVHEIIG---PLT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        85 RHAVS*I----RTT*E*VEQL---PQPVIAAINGIALGGGTELSLACDFRIAAESASLG--LTETTLAiipGA--GGTQR 153
Cdd:PRK08258  89 KMDMPELlaftRMTGDLVKAMracPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAflFTRVGLA---GAdmGACAL 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       154 LPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIAsNGP-IAVRLAKEAISNGIQVDLHTGLQ 232
Cdd:PRK08258 166 LPRIIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLA-AGPtFAHGMTKTMLHQEWDMGLEEAIE 244
                        250       260       270
                 ....*....|....*....|....*....|..
3KQF_C       233 *EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK08258 245 AEAQAQAICMQTEDFRRAYEAFVAKRKPVFEG 276
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
50-265 5.92e-37

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 131.30  E-value: 5.92e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        50 EEANTRVVIL-TGAGEKAFCAGADLKERAG*NEEQVRHAvS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRI 128
Cdd:PRK11423  44 NRPEIRVVILrAPSGSKVWSAGHDIHELPSGGRDPLSYD-DPLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLII 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       129 AAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNG 208
Cdd:PRK11423 123 AASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKA 202
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
3KQF_C       209 PIAVRLAKEAISngIQVDLHT----------GLQ*eKQAYEGvihtKDRLEGLQAFKEKRTP*YKGE 265
Cdd:PRK11423 203 PLAIAVIKEQLR--VLGEAHPmnpdeferiqGLR--RAVYDS----EDYQEGMNAFLEKRKPVFVGH 261
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
12-262 2.35e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 130.34  E-value: 2.35e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        12 VDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKErAG*neeqVRHAVS*I 91
Cdd:PRK05864  13 VDHPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAG-RGFSSGADHKS-AGV----VPHVEGLT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        92 RTT*E------------*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASL-------GLTETTLaiipgaGGTQ 152
Cdd:PRK05864  87 RPTYAlrsmellddvilALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASEL------GLSY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       153 RLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV-DLHTGL 231
Cdd:PRK05864 161 LLPRAIGSSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAaSLEAHM 240
                        250       260       270
                 ....*....|....*....|....*....|..
3KQF_C       232 Q*EKQAYEGV-IHTKDRLEGLQAFKEKRTP*Y 262
Cdd:PRK05864 241 QAEGLGQLFVrLLTANFEEAVAARAEKRPPVF 272
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
18-264 1.43e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 125.07  E-value: 1.43e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKaFCAGADLKERAG*neeqvRHAVS*IRTT*E* 97
Cdd:PRK06563   8 HVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEH-FTAGLDLADVAP------KLAAGGFPFPEGG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 V-------EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTG 170
Cdd:PRK06563  81 IdpwgtvgRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       171 RRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRL----AKEAISNGIQVDLhTGLQ*EKQAyegVIHTKD 246
Cdd:PRK06563 161 DEFDAQEALRLGLVQEVVPPGEQLERAIELAERIARAAPLGVQAtlasARAAVREGEAAAA-AQLPPELRP---LFTSED 236
                        250
                 ....*....|....*...
3KQF_C       247 RLEGLQAFKEKRTP*YKG 264
Cdd:PRK06563 237 AKEGVQAFLERRPARFKG 254
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
50-264 1.74e-34

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 124.85  E-value: 1.74e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        50 EEANTRVVILTGAGeKAFCAGADLKERAG*NEE--QVRHAVS*IRTT----*E*VEQLPQPVIAAINGIALGGGTELSLA 123
Cdd:PRK05981  46 GKAEVRCLVLTGAG-RGFCTGANLQGRGSGGREsdSGGDAGAALETAyhpfLRRLRNLPCPIVTAVNGPAAGVGMSFALM 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       124 CDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEK 203
Cdd:PRK05981 125 GDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHE 204
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
3KQF_C       204 IASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK05981 205 LANGPTVALGLIRKLYWDSPENDFEEQLNLEREAQRIAGKTEDFKEGVGAFLQKRPAQFKG 265
PLN02921 PLN02921
naphthoate synthase
18-262 2.36e-34

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 126.06  E-value: 2.36e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERaG*NEEQVRHAVS*IRTT*E* 97
Cdd:PLN02921  76 GIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVR-GKDGYVGPDDAGRLNVLDLQ 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        98 VE--QLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 175
Cdd:PLN02921 155 IQirRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTA 234
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       176 QEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAIsNGIQvDLHTGLQ*-EKQAYEGVIHTKDRLEGLQAF 254
Cdd:PLN02921 235 SEALKMGLVNTVVPLDELEGETVKWCREILRNSPTAIRVLKSAL-NAAD-DGHAGLQElGGNATLLFYGSEEGNEGRTAY 312

                 ....*...
3KQF_C       255 KEKRTP*Y 262
Cdd:PLN02921 313 LEGRAPDF 320
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
19-211 8.72e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 122.82  E-value: 8.72e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEAntRVVILTGAGEKaFCAGADLKERAG*NEEQVRHAVS*IRTT*E*V 98
Cdd:PRK08150  12 VATIGLNRPAKRNALNDGLIAALRAAFARLPEGV--RAVVLHGEGDH-FCAGLDLSELRERDAGEGMHHSRRWHRVFDKI 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        99 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 178
Cdd:PRK08150  89 QYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDAQEG 168
                        170       180       190
                 ....*....|....*....|....*....|...
3KQF_C       179 KEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIA 211
Cdd:PRK08150 169 ERLGLAQYLVPAGEALDKAMELARRIAQNAPLT 201
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
19-265 2.16e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 121.81  E-value: 2.16e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*V 98
Cdd:PRK06072  10 YAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPDFAIDLRETFYPIIREIRFS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        99 EQLpqpVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRISAQEA 178
Cdd:PRK06072  89 DKI---YISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQ-RFYEILVLGGEFTAEEA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       179 KEYGLVEFVV-PVHlleeKAIEIAEKIaSNGPIAVRLAKEAISNGIQV-DLHTGLQ*EK--QAYEGVihTKDRLEGLQAF 254
Cdd:PRK06072 165 ERWGLLKISEdPLS----DAEEMANRI-SNGPFQSYIAAKRMINLVLYnDLEEFLEYESaiQGYLGK--TEDFKEGISSF 237
                        250
                 ....*....|.
3KQF_C       255 KEKRTP*YKGE 265
Cdd:PRK06072 238 KEKREPKFKGI 248
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
22-219 2.58e-33

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 122.04  E-value: 2.58e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        22 ISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEkAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*VEQL 101
Cdd:PRK09120  21 VTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD-AWSAGMDLKEYFRETDAQPEILQERIRREAYGWWRR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       102 ----PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 177
Cdd:PRK09120 100 lrwyQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGETFTGRK 179
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
3KQF_C       178 AKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAI 219
Cdd:PRK09120 180 AAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGF 221
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
45-264 3.37e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 121.26  E-value: 3.37e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NE----------EQVRHAVS*IRTt*e*veqLPQPVIAAINGIAL 114
Cdd:PRK07511  39 LNTAERDPSIRAVVLTGAG-GFFCAGGNLNRLLENRAkppsvqaasiDGLHDWIRAIRA-------FPKPVIAAVEGAAA 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       115 GGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLV-EFVVPVHLL 193
Cdd:PRK07511 111 GAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHALGVVnRLAEPGQAL 190
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
3KQF_C       194 EEkAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK07511 191 AE-ALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLEKRAPDYKR 260
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
55-206 1.69e-32

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 119.62  E-value: 1.69e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        55 RVVILTGAGEkAFCAGADLKerAG*NEEQVRHAVS*------IRTt*e*veQLPQPVIAAINGIALGGGTELSLACDFRI 128
Cdd:PRK08259  49 SVAVLWGAGG-TFCAGADLK--AVGTGRGNRLHPSGdgpmgpSRM------RLSKPVIAAVSGYAVAGGLELALWCDLRV 119
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
3KQF_C       129 AAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIAS 206
Cdd:PRK08259 120 AEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAA 197
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
45-228 2.08e-32

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 118.92  E-value: 2.08e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGeKAFCAGADLKERAg*NEEQVRHAVS*IR---TT*E*VEQLPQPVIAAINGIALGGGTELS 121
Cdd:PRK07938  37 ITAAGADPDTRVVVLRAEG-RGFNAGVDIKELQ--ATPGFTALIDANRgcfAAFRAVYECAVPVIAAVHGFCLGGGIGLV 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       122 LACDFRIAAESASLGLTEttlaIIPGA-GGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEI 200
Cdd:PRK07938 114 GNADVIVASDDATFGLPE----VDRGAlGAATHLQRLVPQHLMRALFFTAATITAAELHHFGSVEEVVPRDQLDEAALEV 189
                        170       180
                 ....*....|....*....|....*....
3KQF_C       201 AEKIASNGPIAVRLAKEAIsNGIQ-VDLH 228
Cdd:PRK07938 190 ARKIAAKDTRVIRAAKEAL-NGIDpQDVE 217
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
19-264 2.31e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 116.70  E-value: 2.31e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLK--------ERAG*NEEQVRHAvs* 90
Cdd:PRK07468  15 VATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGwmraqmtaDRATRIEEARRLA--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        91 irTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRlIGVGRAKELIYTG 170
Cdd:PRK07468  91 --MMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSA 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       171 RRISAQEAKEYGLVEFVVPVHLLEEkAIEiAEKIA--SNGPIAVRLAKEAISngiqvDLHTGLQ*EKQAYE-----GVIH 243
Cdd:PRK07468 168 RLFDAEEAVRLGLLSRVVPAERLDA-AVE-AEVTPylSCAPGAVAAAKALVR-----ALGAPIDEAVIDATiealaDTWE 240
                        250       260
                 ....*....|....*....|.
3KQF_C       244 TKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK07468 241 TEEAREGIAAFFDKRAPAWRG 261
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
18-265 1.45e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 114.36  E-value: 1.45e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQInEEANTRVVILTGAGeKAFCAGADLKER-AG*NEEQVRHAVS*IRTT*E 96
Cdd:PRK07659  15 RVATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNG-RGFSAGGDIKMMlSSNDESKFDGVMNTISEIVV 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        97 *VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQ 176
Cdd:PRK07659  93 TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSAT 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       177 EAKEYGLVEFVVPvhllEEKAIEIAEKIAS--NGPIAVRLAKEAISNGIQV-DLHTGLQ*EKQAYEGVIHTKDRLEGLQA 253
Cdd:PRK07659 173 EALDLGLIDEVIG----GDFQTAAKQKISEwlQKPLKAMIETKQIYCELNRsQLEQVLQLEKRAQYAMRQTADHKEGIRA 248
                        250
                 ....*....|..
3KQF_C       254 FKEKRTP*YKGE 265
Cdd:PRK07659 249 FLEKRLPVFKGE 260
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
47-238 2.42e-30

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 119.17  E-value: 2.42e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         47 QINEEANTRVVILTGAGekAFCAGADLK----ERAG*NEEQVRHAVS*Irtt*E*VEQLPQPVIAAINGIALGGGTELSL 122
Cdd:TIGR02441  54 WTNEAIKSAVLISGKPG--SFVAGADIQmiaaCKTAQEVTQLSQEGQEM---FERIEKSQKPIVAAISGSCLGGGLELAL 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        123 ACDFRIAAESAS--LGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVP-----VHLLEE 195
Cdd:TIGR02441 129 ACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVDplgpgLKPAEE 208
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
3KQF_C        196 KAIEIAEKiasngpIAVRLAKEAISNGIQVDLHTGLQ*EKQAY 238
Cdd:TIGR02441 209 NTIEYLEE------VAVKFAQGLANGKLSINRDKGLVHKITQY 245
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
8-264 7.22e-30

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 112.81  E-value: 7.22e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         8 QNISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLK-ERAG*NEEQVRH 86
Cdd:PRK07327  11 PALRFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLAlVEEMADDFEVRA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        87 AV-S*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 165
Cdd:PRK07327  90 RVwREARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKY 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       166 LIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISN-----GIQVDlhTGLQ*EKQAYEG 240
Cdd:PRK07327 170 YLLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYALNNwlrmaGPTFD--TSLALEFMGFSG 247
                        250       260
                 ....*....|....*....|....
3KQF_C       241 vihtKDRLEGLQAFKEKRTP*YKG 264
Cdd:PRK07327 248 ----PDVREGLASLREKRAPDFPG 267
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
17-264 1.73e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 111.27  E-value: 1.73e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        17 PHVVKISLNR-ERQANSLSLALLEELQNILTQINEEAntRVVILTGAGeKAFCAGADLKerAG*NEEQVRHAVS*IRTT* 95
Cdd:PRK07854   8 GQVLTIELQRpERRNALNAELCEELREAVRKAVDESA--RAIVLTGQG-TVFCAGADLS--GDVYADDFPDALIEMLHA- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        96 e*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 175
Cdd:PRK07854  82 --IDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       176 QEAKEYGLVEFVVPVhlleEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTglQ*EKQAYEGVIHTKDRLEGLQAFK 255
Cdd:PRK07854 160 EQALATGMANRIGTL----ADAQAWAAEIAGLAPLALQHAKRVLNDDGAIEEAW--PAHKELFDKAWASQDAIEAQVARI 233

                 ....*....
3KQF_C       256 EKRTP*YKG 264
Cdd:PRK07854 234 EKRPPKFQG 242
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
12-219 6.56e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 108.12  E-value: 6.56e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        12 VDYAT-PHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE---RAG*NEEQVRHA 87
Cdd:PRK08290   6 VRYEVaGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAG-KHFSAGHDLGSgtpGRDRDPGPDQHP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        88 VS*IR-TT*E*VEQ------------------LPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLaiipGA 148
Cdd:PRK08290  85 TLWWDgATKPGVEQryarewevylgmcrrwrdLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRM----GI 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
3KQF_C       149 GGTQRL--PRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAI 219
Cdd:PRK08290 161 PGVEYFahPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAV 233
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
57-220 2.05e-27

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 105.31  E-value: 2.05e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        57 VILTGaGEKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLG 136
Cdd:PRK05869  55 VILYG-GHEIFSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFG 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       137 LTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLV-EFVVPVHLLeEKAIEIAEKIASNGPIAVRLA 215
Cdd:PRK05869 134 ATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIdEMVAPDDVY-DAAAAWARRFLDGPPHALAAA 212

                 ....*
3KQF_C       216 KEAIS 220
Cdd:PRK05869 213 KAGIS 217
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
55-219 4.97e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 104.81  E-value: 4.97e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        55 RVVILTGAGeKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESAS 134
Cdd:PRK05870  49 HALVVTGAG-KAFCAGADLTALGAAPGRPAEDGLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKAL 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       135 LGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVV--PVhlleEKAIEIAEKIASNGPIAV 212
Cdd:PRK05870 128 FDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLALMVAddPV----AAALELAAGPAAAPRELV 203

                 ....*..
3KQF_C       213 RLAKEAI 219
Cdd:PRK05870 204 LATKASM 210
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
56-263 3.36e-25

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 101.25  E-value: 3.36e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        56 VVILTGAG--EK----AFCAGADLKER--------AG*NEEQVRHAVS*iRTT*E*VEQL----PQPVIAAINGIALGGG 117
Cdd:PRK08321  72 CVLLTGNGpsPKdggwAFCSGGDQRIRgrdgyqyaEGDEADTVDPARAG-RLHILEVQRLirfmPKVVIAVVPGWAAGGG 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       118 TELSLACDFRIA-AESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEK 196
Cdd:PRK08321 151 HSLHVVCDLTLAsREHARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETE 230
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
3KQF_C       197 AIEIAEKIASNGPIAVRLAKEA---ISNGIqvdlhTGLQ-----*EKQAYegviHTKDRLEGLQAFKEKRTP*YK 263
Cdd:PRK08321 231 ALEWAREINGKSPTAMRMLKYAfnlTDDGL-----VGQQlfageATRLAY----MTDEAQEGRDAFLEKRDPDWS 296
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
16-206 2.08e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 96.26  E-value: 2.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        16 TPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERA-G*NEEQVRHAVS*IRTT 94
Cdd:PRK08272  17 TGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAG-KGFCAGYDLSAYAeGSSSGGGGGAYPGKRQA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        95 *E*VEQLP------------------------QPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAG- 149
Cdd:PRK08272  96 VNHLPDDPwdpmidyqmmsrfvrgfmslwhahKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPATGm 175
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
3KQF_C       150 GTQRLprliGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIAS 206
Cdd:PRK08272 176 WAYRL----GPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAA 228
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
22-219 1.76e-21

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 91.38  E-value: 1.76e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         22 ISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKE-----RAG*NEEQVR---------HA 87
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRAlyeaaKAGGGEAGRDffreeyrlnYL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         88 VS*irtt*e*veQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG-VGRakel 166
Cdd:pfam16113  84 IA----------TYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGeLGL---- 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
3KQF_C        167 iY---TGRRISAQEAKEYGLVEFVVPVHLLEekaiEIAEKIASNGPIAVRLAKEAI 219
Cdd:pfam16113 150 -YlalTGARLNGADALAAGLATHYVPSARLP----ALEEALAALDWSDPADVDAVL 200
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
15-219 1.10e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 85.23  E-value: 1.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        15 ATPHVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAgEKAFCAGADLKERAG*neeqvrhAVS*IRTT 94
Cdd:PRK06023  12 AHPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGT-EGCFSAGNDMQDFLAA-------AMGGTSFG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        95 *E*VEQL------PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIY 168
Cdd:PRK06023  84 SEILDFLialaeaEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLA 163
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
3KQF_C       169 TGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAI 219
Cdd:PRK06023 164 LGEGFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARDLM 214
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
19-259 2.09e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 84.79  E-value: 2.09e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        19 VVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE-RAG*NEEQVRHAVS*IRTT*E- 96
Cdd:PRK07260  12 LATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG-KVFSVGGDLVEmKRAVDEDDVQSLVKIAELVNEi 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        97 --*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 174
Cdd:PRK07260  91 sfAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLAMTGEALT 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       175 AQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTKDRLEGLQAF 254
Cdd:PRK07260 171 AEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNSYAAIKSLVWESFFKGWEDYAKLELALQESLAFKEDFKEGVRAF 250

                 ....*
3KQF_C       255 KEKRT 259
Cdd:PRK07260 251 SERRR 255
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
24-265 6.46e-19

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 83.32  E-value: 6.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        24 LNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E---*VEQ 100
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLAWMQQSADLDYNTNLDDARELAElmyNLYR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       101 LPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPgAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE 180
Cdd:PRK05674 100 LKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAP-AVISPFVVKAIGERAARRYALTAERFDGRRARE 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       181 YGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIHTK-DRLEGLQAFKEKRT 259
Cdd:PRK05674 179 LGLLAESYPAAELEAQVEAWIANLLLNSPQALRASKDLLREVGDGELSPALRRYCENAIARIRVSaEGQEGLRAFLEKRT 258

                 ....*.
3KQF_C       260 P*YKGE 265
Cdd:PRK05674 259 PAWQTD 264
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
45-184 8.41e-19

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 83.19  E-value: 8.41e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGeKAFCAGADLKERAG*NEEQVRHAVS*IRTT*E*VEQ---LPQPVIAAINGIALGGGTELS 121
Cdd:PRK07827  42 LRAAAADPAVRAVVLTHTG-GTFCAGADLSEAGGGGGDPYDAAVARAREMTALLRAiveLPKPVIAAIDGHVRAGGFGLV 120
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
3KQF_C       122 LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLigVGRAKELIY-TGRRISAQEAKEYGLV 184
Cdd:PRK07827 121 GACDIVVAGPESTFALTEARIGVAPAIISLTLLPRL--SPRAAARYYlTGEKFGAAEAARIGLV 182
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
44-251 1.29e-15

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 74.23  E-value: 1.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        44 ILTQINEEANTRVVILTGAGEkAFCAGAdlkerag*NEEQVRHAVS*IRTT*E*-----VEQLPQPVIAAINGIALGGGT 118
Cdd:PRK07110  40 AFDTIAQDPRYKVVILTGYPN-YFATGG--------TQEGLLSLQTGKGTFTEAnlyslALNCPIPVIAAMQGHAIGGGL 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       119 ELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAI 198
Cdd:PRK07110 111 VLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELKKRGVPFPVLPRAEVLEKAL 190
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
3KQF_C       199 EIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ*EKQAYEGVIH---TKDRLEGL 251
Cdd:PRK07110 191 ELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQEVAMHEKTFHqpeVKRRIESL 246
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
22-220 6.07e-15

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 73.32  E-value: 6.07e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        22 ISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKE-----RAG*NEEQVR---------HA 87
Cdd:PRK05617  16 ITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRAlyeaaRAGDPLAADRffreeyrlnAL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        88 VS*irtt*e*veQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG-VGRAKEL 166
Cdd:PRK05617  96 IA----------RYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGaLGTYLAL 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
3KQF_C       167 iyTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNGPIAVRLAKEAIS 220
Cdd:PRK05617 166 --TGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGADVVDAALAAFA 217
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
106-189 1.63e-14

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 71.48  E-value: 1.63e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       106 IAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVE 185
Cdd:PRK08788 125 IALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLVD 204

                 ....
3KQF_C       186 FVVP 189
Cdd:PRK08788 205 VLVE 208
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
45-218 2.45e-14

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 71.06  E-value: 2.45e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGEK-AFCAGADLKERAG*NEEQVRHAVS*IRTT*E*VEQLPQPV--IAAINGIALGGGTELS 121
Cdd:PLN03214  47 LTALENDPTVRGVVFASGLRRdVFTAGNDIAELYAPKTSAARYAEFWLTQTTFLVRLLRSRLatVCAIRGACPAGGCAVS 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       122 LACDFRIAAESASLGLTETTLAI-IPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEI 200
Cdd:PLN03214 127 LCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASA 206
                        170
                 ....*....|....*...
3KQF_C       201 AEKiASNGPIAVRLAKEA 218
Cdd:PLN03214 207 MER-ALKLPSAARAATKA 223
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
22-209 1.80e-13

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 69.36  E-value: 1.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        22 ISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE----------RAG*NEEQVRHAVS*I 91
Cdd:PLN02988  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAvvrdieqgnwRLGANFFSDEYMLNYV 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        92 RTT*E*VEqlpqpvIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGR 171
Cdd:PLN02988 101 MATYSKAQ------VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVGLTGA 173
                        170       180       190
                 ....*....|....*....|....*....|....*...
3KQF_C       172 RISAQEAKEYGLVEFVVPVHLLEEKAIEIAeKIASNGP 209
Cdd:PLN02988 174 RLDGAEMLACGLATHFVPSTRLTALEADLC-RIGSNDP 210
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
6-239 3.61e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 68.06  E-value: 3.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C         6 QLQNISVDYATPhVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGAD----------LKE 75
Cdd:PRK12478   3 DFQTLLYTTAGP-VATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGYDfgggfqhwgeAMM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        76 RAG*NEEQVRHAVS*IRTT*E-----*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGlteTTLAIIPGAGG 150
Cdd:PRK12478  81 TDGRWDPGKDFAMVTARETGPtqkfmAIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIG---TPYSRMWGAYL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       151 TQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLEEKAIEIAEKIASNgPIAVRLAKEAISNgiqvdlhtg 230
Cdd:PRK12478 158 TGMWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEVATELARI-PLSQLQAQKLIVN--------- 227

                 ....*....
3KQF_C       231 lq*ekQAYE 239
Cdd:PRK12478 228 -----QAYE 231
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
18-249 2.28e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 65.98  E-value: 2.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        18 HVVKISLNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE--RAG*NEEQVRHAVS*IRTT* 95
Cdd:PLN02874  20 RVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMfyDGRESDDSCLEVVYRMYWLC 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        96 E*VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG-VGraKELIYTGRRIS 174
Cdd:PLN02874  99 YHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGhLG--EYLALTGARLN 176
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
3KQF_C       175 AQEAKEYGLVEFVVPVHLLEEKAIEIAEkIASNGPIAVRLAKEAISNGIQVDLHTGLQ*eKQAYEGVIHTKDRLE 249
Cdd:PLN02874 177 GKEMVACGLATHFVPSEKLPELEKRLLN-LNSGDESAVQEAIEEFSKDVQADEDSILN--KQSWINECFSKDTVE 248
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
24-203 6.77e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 64.70  E-value: 6.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        24 LNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGADLKE----RAG*NEEQVRHAVS*IRTT*E*VE 99
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSlyhlRKRGSPDAIREFFSSLYSFIYLLG 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       100 QLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLigVGRAKELI-YTGRRISAQEA 178
Cdd:PLN02157 131 TYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHL--PGRLGEYLgLTGLKLSGAEM 208
                        170       180
                 ....*....|....*....|....*
3KQF_C       179 KEYGLVefvvpVHLLEEKAIEIAEK 203
Cdd:PLN02157 209 LACGLA-----THYIRSEEIPVMEE 228
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
51-185 7.84e-09

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 54.69  E-value: 7.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        51 EANTRVVILTGAGEkAFCAGADLKERAG*NEEQVRHAVS*irtt*e*vEQL----------PQPVIAAINGIALGGGTEL 120
Cdd:PRK07112  44 EHAATIVVLEGLPE-VFCFGADFSAIAEKPDAGRADLIDA--------EPLydlwhrlatgPYVTIAHVRGKVNAGGIGF 114
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
3KQF_C       121 SLACDFRIAAESASLGLTETTLAIIPgAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVE 185
Cdd:PRK07112 115 VAASDIVIADETAPFSLSELLFGLIP-ACVLPFLIRRIGTQKAHYMTLMTQPVTAQQAFSWGLVD 178
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
24-183 8.49e-09

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 55.37  E-value: 8.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        24 LNRERQANSLSLALLEELQNILTQINEEANTRVVILTGAGeKAFCAGAD-LKERAG*NEEQVRHAVS*IRTT*E*VEQLP 102
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADvVSLYHLINEGNVEECKLFFENLYKFVYLQG 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       103 ---QPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRISAQEAK 179
Cdd:PLN02851 136 tylKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGY-LGEYLALTGQKLNGVEMI 214

                 ....
3KQF_C       180 EYGL 183
Cdd:PLN02851 215 ACGL 218
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
45-205 3.13e-08

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 52.79  E-value: 3.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        45 LTQINEEANTRVVILTGAGEKAFCAGADLK--ERAG*NEEQVRHAVS*IRTT*E*VEQLPQPVIAAINGIALGGGTELSL 122
Cdd:PLN02267  35 LRQVKSQATPGSVLITTAEGKFFSNGFDLAwaQAAGSAPSRLHLMVAKLRPLVADLISLPMPTIAAVTGHASAAGFILAL 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       123 ACDFRIA-AESASLGLTETTLAIIPGAGGTQRLPRLIGVGRA-KELIYTGRRISAQEAKEYGLVEfvvPVHLLEEKAIEI 200
Cdd:PLN02267 115 SHDYVLMrKDRGVLYMSEVDIGLPLPDYFMALLRAKIGSPAArRDVLLRAAKLTAEEAVEMGIVD---SAHDSAEETVEA 191

                 ....*
3KQF_C       201 AEKIA 205
Cdd:PLN02267 192 AVRLG 196
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
44-230 8.02e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 51.51  E-value: 8.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C        44 ILTQINE-----EANTRVVILTGAgEKAFCAGADLKERAG*NEEqvrhAVS*IRTT*E*VEQL---PQPVIAAINGIALG 115
Cdd:PRK06213  30 MIDALNAaldqaEDDRAVVVITGQ-PGIFSGGFDLKVMTSGAQA----AIALLTAGSTLARRLlshPKPVIVACTGHAIA 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KQF_C       116 GGTELSLACDFRIAAESA-SLGLTETTLAI-IPGAG---GTQRLPRlIGVGRAkelIYTGRRISAQEAKEYGLVEFVVPV 190
Cdd:PRK06213 105 KGAFLLLSADYRIGVHGPfKIGLNEVAIGMtMPHAAielARDRLTP-SAFQRA---VINAEMFDPEEAVAAGFLDEVVPP 180
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
3KQF_C       191 HLLEEKAIEIAEKIASNGPIAVRLAK--------EAISNGIQVDL-HTG 230
Cdd:PRK06213 181 EQLLARAQAAARELAGLNMGAHAATKlkvraaalEAIRAAIEGDAaEFG 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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