NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|313507265|pdb|3ADK|A]
View 

Chain A, ADENYLATE KINASE

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11492279)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 7-194 7.17e-133

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


:

Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 369.92  E-value: 7.17e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A          7 KKSKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVD 86
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         87 TSKGFLIDGYPREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYE 166
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
3ADK_A        167 KRGIVRKVNAEGSVDDVFSQVCTHLDTL 194
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
 
Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 7-194 7.17e-133

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 369.92  E-value: 7.17e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A          7 KKSKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVD 86
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         87 TSKGFLIDGYPREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYE 166
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
3ADK_A        167 KRGIVRKVNAEGSVDDVFSQVCTHLDTL 194
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 11-183 1.23e-74

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 222.88  E-value: 1.23e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSKG 90
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERL-KKPDCKKG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       91 FLIDGYPREVKQGEEFERKI---GQPTLLLYVDAGPETMTKRLLKRGET-------------------SGRVDDNEETIK 148
Cdd:cd01428  80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                       170       180       190
                ....*....|....*....|....*....|....*
3ADK_A      149 KRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDV 183
Cdd:cd01428 160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
14-168 1.69e-71

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 214.48  E-value: 1.69e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         14 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSKGFLI 93
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERL-EQNDCKNGFLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         94 DGYPREVKQGEEFERKIG---QPTLLLYVDAGPETMTKRLLKRGET---------------------------SGRVDDN 143
Cdd:pfam00406  80 DGFPRTVPQAEALEELLErgiKLDYVIEFDVPDEVLVERLTGRRIHpnsgrsyhlefnppkvpgkddvtgeplVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
3ADK_A        144 EETIKKRLETYYKATEPVIAFYEKR 168
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 10-191 6.79e-66

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 201.12  E-value: 6.79e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSK 89
Cdd:COG0563   2 RIILL-GPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL-AQPDCAN 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       90 GFLIDGYPREVKQGEEFER---KIGQP-TLLLYVDAGPETMTKRLLKR---------------------------GETSG 138
Cdd:COG0563  80 GFILDGFPRTVAQAEALDEllaELGIKlDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQ 159

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
3ADK_A      139 RVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQVCTHL 191
Cdd:COG0563 160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 10-194 1.85e-63

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 194.98  E-value: 1.85e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSK 89
Cdd:PRK00279   2 RLILL-GPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL-AQPDCKN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        90 GFLIDGYPREVKQGEEFER---KIGQP-TLLLYVDAGPETMTKRLLKR---------------------------GETSG 138
Cdd:PRK00279  80 GFLLDGFPRTIPQAEALDEmlkELGIKlDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
3ADK_A       139 RVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQVCTHLDTL 194
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
 
Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 7-194 7.17e-133

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 369.92  E-value: 7.17e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A          7 KKSKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVD 86
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         87 TSKGFLIDGYPREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYE 166
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
3ADK_A        167 KRGIVRKVNAEGSVDDVFSQVCTHLDTL 194
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 11-183 1.23e-74

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 222.88  E-value: 1.23e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSKG 90
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERL-KKPDCKKG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       91 FLIDGYPREVKQGEEFERKI---GQPTLLLYVDAGPETMTKRLLKRGET-------------------SGRVDDNEETIK 148
Cdd:cd01428  80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                       170       180       190
                ....*....|....*....|....*....|....*
3ADK_A      149 KRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDV 183
Cdd:cd01428 160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
14-168 1.69e-71

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 214.48  E-value: 1.69e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         14 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSKGFLI 93
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERL-EQNDCKNGFLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         94 DGYPREVKQGEEFERKIG---QPTLLLYVDAGPETMTKRLLKRGET---------------------------SGRVDDN 143
Cdd:pfam00406  80 DGFPRTVPQAEALEELLErgiKLDYVIEFDVPDEVLVERLTGRRIHpnsgrsyhlefnppkvpgkddvtgeplVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
3ADK_A        144 EETIKKRLETYYKATEPVIAFYEKR 168
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 11-187 6.79e-71

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 213.00  E-value: 6.79e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVS-SGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKvDTSK 89
Cdd:TIGR01359   1 VVFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQED-GSSK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         90 GFLIDGYPREVKQGEEFERKIGQ---PTLLLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYE 166
Cdd:TIGR01359  80 KFLIDGFPRNEENLEAWEKLMDNkvnFKFVLFFDCPEETMIKRLLKRGQTSGRVDDNIETLKKRFRTYNEETLPIIEHFE 159

                         170       180
                  ....*....|....*....|.
3ADK_A        167 KRGIVRKVNAEGSVDDVFSQV 187
Cdd:TIGR01359 160 NKGKVKEINAEGSVEEVFEDV 180
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 10-191 6.79e-66

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 201.12  E-value: 6.79e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSK 89
Cdd:COG0563   2 RIILL-GPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL-AQPDCAN 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       90 GFLIDGYPREVKQGEEFER---KIGQP-TLLLYVDAGPETMTKRLLKR---------------------------GETSG 138
Cdd:COG0563  80 GFILDGFPRTVAQAEALDEllaELGIKlDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQ 159

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
3ADK_A      139 RVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQVCTHL 191
Cdd:COG0563 160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 10-194 1.85e-63

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 194.98  E-value: 1.85e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSK 89
Cdd:PRK00279   2 RLILL-GPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL-AQPDCKN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        90 GFLIDGYPREVKQGEEFER---KIGQP-TLLLYVDAGPETMTKRLLKR---------------------------GETSG 138
Cdd:PRK00279  80 GFLLDGFPRTIPQAEALDEmlkELGIKlDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
3ADK_A       139 RVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQVCTHLDTL 194
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 10-187 2.44e-56

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 177.04  E-value: 2.44e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVDTSK 89
Cdd:TIGR01351   1 RLVLL-GPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         90 GFLIDGYPREVKQGEEFERKI-GQPTLLLYVDAGPETMTKRLLKRG--ETSGRV-------------------------D 141
Cdd:TIGR01351  80 GFILDGFPRTLSQAEALDALLeEPIDAVIELDVPDEELVERLSGRRicPSCGRVyhlkfnppkvpgcddctgellvqreD 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
3ADK_A        142 DNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQV 187
Cdd:TIGR01351 160 DTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRI 205
PLN02200 PLN02200
adenylate kinase family protein
 11-187 4.10e-54

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 172.00  E-value: 4.10e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKvDTSKg 90
Cdd:PLN02200  45 ITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESS-DNNK- 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        91 FLIDGYPREVKQGEEFERKIG-QPTLLLYVDAGPETMTKRLLKRGEtsGRVDDNEETIKKRLETYYKATEPVIAFYEKRG 169
Cdd:PLN02200 123 FLIDGFPRTEENRIAFERIIGaEPNVVLFFDCPEEEMVKRVLNRNQ--GRVDDNIDTIKKRLKVFNALNLPVIDYYSKKG 200

                        170
                 ....*....|....*...
3ADK_A       170 IVRKVNAEGSVDDVFSQV 187
Cdd:PLN02200 201 KLYTINAVGTVDEIFEQV 218
PRK14531 PRK14531
adenylate kinase; Provisional
 8-192 5.46e-47

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 152.27  E-value: 5.46e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         8 KSKIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvaKVDT 87
Cdd:PRK14531   2 KQRLLFL-GPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQL--KALN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        88 SKGFLIDGYPREVKQGEEFE---RKIGQP---TLLLYVDagPETMTKRLLKRgetsGRVDDNEETIKKRLETYYKATEPV 161
Cdd:PRK14531  79 SGGWLLDGFPRTVAQAEALEpllEELKQPieaVVLLELD--DAVLIERLLAR----GRADDNEAVIRNRLEVYREKTAPL 152

                        170       180       190
                 ....*....|....*....|....*....|.
3ADK_A       162 IAFYEKRGIVRKVNAEGSVDDVFSQVCTHLD 192
Cdd:PRK14531 153 IDHYRQRGLLQSVEAQGSIEAITERIEKVLA 183
PRK14527 PRK14527
adenylate kinase; Provisional
 8-187 1.06e-46

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 151.87  E-value: 1.06e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         8 KSKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVDT 87
Cdd:PRK14527   5 KNKVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        88 SKGFliDGYPREVKQGEEFER---KIGQPTL-LLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIA 163
Cdd:PRK14527  85 RVIF--DGFPRTLAQAEALDRlleELGARLLaVVLLEVPDEELIRRIVERARQEGRSDDNEETVRRRQQVYREQTQPLVD 162

                        170       180
                 ....*....|....*....|....
3ADK_A       164 FYEKRGIVRKVNAEGSVDDVFSQV 187
Cdd:PRK14527 163 YYEARGHLKRVDGLGTPDEVYARI 186
PRK14528 PRK14528
adenylate kinase; Provisional
 10-187 6.29e-42

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 139.38  E-value: 6.29e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVaKVDTSK 89
Cdd:PRK14528   3 NIIFM-GPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIR-EADCKN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        90 GFLIDGYPREVKQGEEFERKIGQPTL----LLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFY 165
Cdd:PRK14528  81 GFLLDGFPRTVEQADALDALLKNEGKsidkAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLDFY 160

                        170       180
                 ....*....|....*....|..
3ADK_A       166 EKRGIVRKVNAEGSVDDVFSQV 187
Cdd:PRK14528 161 AAQKKLSQVNGVGSLEEVTSLI 182
AAA_17 pfam13207
AAA domain;
15-148 7.45e-42

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 137.37  E-value: 7.45e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         15 VGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSarGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSKGFLID 94
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERI-AEEAGEGGVIVD 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         95 GYPREVKQGEE---FERKIGQ---PTLLLYVDAGPETMTKRLLKRgETSGRVDDNEETIK 148
Cdd:pfam13207  78 GHPRIKTPAGYlpgLPVEVLRelkPDAIILLEADPEEILERRLKD-RTRGRDDDSEEEIR 136
PRK14532 PRK14532
adenylate kinase; Provisional
 11-183 9.00e-41

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 136.49  E-value: 9.00e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        11 IIFvvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSKG 90
Cdd:PRK14532   4 ILF--GPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERL-PEAEAAGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        91 FLIDGYPREVKQGEEF-------ERKIgQPTLLLYVDagPETMTKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIA 163
Cdd:PRK14532  81 AIFDGFPRTVAQAEALdkmlasrGQKI-DVVIRLKVD--DEALIERIVKRFEEQGRPDDNPEVFVTRLDAYNAQTAPLLP 157

                        170       180
                 ....*....|....*....|
3ADK_A       164 FYEKRGIVRKVNAEGSVDDV 183
Cdd:PRK14532 158 YYAGQGKLTEVDGMGSIEAV 177
adk PRK02496
adenylate kinase; Provisional
 10-183 1.85e-39

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 132.95  E-value: 1.85e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVDTSK 89
Cdd:PRK02496   3 RLIFL-GPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERL-QQPDAAN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        90 GFLIDGYPREVKQG---EEFERKIGQP-TLLLYVDAGPETMTKRLLKRgetsGRVDDNEETIKKRLETYYKATEPVIAFY 165
Cdd:PRK02496  81 GWILDGFPRKVTQAaflDELLQEIGQSgERVVNLDVPDDVVVERLLAR----GRKDDTEEVIRRRLEVYREQTAPLIDYY 156

                        170
                 ....*....|....*...
3ADK_A       166 EKRGIVRKVNAEGSVDDV 183
Cdd:PRK02496 157 RDRQKLLTIDGNQSVEAV 174
PLN02842 PLN02842
nucleotide kinase
 14-192 4.22e-36

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 131.52  E-value: 4.22e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        14 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVDTSKGFLI 93
Cdd:PLN02842   2 ISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDAKEKGWLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        94 DGYPREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKR-------------------GETSGRV----DDNEETIKKR 150
Cdd:PLN02842  82 DGYPRSFAQAQSLEKLKIRPDIFILLDVPDEILIDRCVGRrldpvtgkiyhiknfppesEEIKARLitrpDDTEEKVKAR 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
3ADK_A       151 LETYYKATEPVIAFYEKrgIVRKVNAEGSVDDVFSQVCTHLD 192
Cdd:PLN02842 162 LQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLLS 201
PRK14530 PRK14530
adenylate kinase; Provisional
 12-192 1.46e-35

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 124.13  E-value: 1.46e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        12 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRA---------EVSSGSARgkmlsEIMEKGQLVPLETVLDMLRDAMv 82
Cdd:PRK14530   6 ILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnkqmdisdmDTEYDTPG-----EYMDAGELVPDAVVNEIVEEAL- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        83 akvDTSKGFLIDGYPREVKQGEEFErKIGQPTLLLYVDAGPETMTKRLLKR---------------------------GE 135
Cdd:PRK14530  80 ---SDADGFVLDGYPRNLEQAEYLE-SITDLDVVLYLDVSEEELVDRLTGRrvcpdcganyhvefnqpeeegvcdecgGE 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
3ADK_A       136 TSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQVCTHLD 192
Cdd:PRK14530 156 LIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAID 212
PLN02674 PLN02674
adenylate kinase
 7-187 1.03e-30

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 112.29  E-value: 1.03e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         7 KKSKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAKVD 86
Cdd:PLN02674  29 KPDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAM-KKPS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        87 TSKGFLIDGYPREVKQGEEFERKIGQ------PTLLLYVDAG--PETMTKRLLKrgETSGRV------------------ 140
Cdd:PLN02674 108 CQKGFILDGFPRTVVQAQKLDEMLAKqgakidKVLNFAIDDAilEERITGRWIH--PSSGRTyhtkfappkvpgvddvtg 185

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
3ADK_A       141 -------DDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDVFSQV 187
Cdd:PLN02674 186 epliqrkDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEV 239
PRK13808 PRK13808
adenylate kinase; Provisional
 12-183 1.24e-29

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 111.52  E-value: 1.24e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        12 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDaMVAKVDTSKGF 91
Cdd:PRK13808   3 LILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISD-RIEQPDAANGF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        92 LIDGYPREVKQGEEFERKIGQPTLL------LYVDAGP-----ETMTKRLLKRGETSgRVDDNEETIKKRLETYYKATEP 160
Cdd:PRK13808  82 ILDGFPRTVPQAEALDALLKDKQLKldavveLRVNEGAllarvETRVAEMRARGEEV-RADDTPEVLAKRLASYRAQTEP 160

                        170       180
                 ....*....|....*....|...
3ADK_A       161 VIAFYEKRGIVRKVNAEGSVDDV 183
Cdd:PRK13808 161 LVHYYSEKRKLLTVDGMMTIDEV 183
PLN02459 PLN02459
probable adenylate kinase
 3-169 3.15e-28

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 106.08  E-value: 3.15e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         3 EEKLKKSKIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMV 82
Cdd:PLN02459  24 LAKGRNVNWVFL-GCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        83 AKVDT-SKGFLIDGYPREVKQGEEFER----------KIGQPTLLLYV-----------------------DAGPETMTK 128
Cdd:PLN02459 103 AGEEEgESGFILDGFPRTVRQAEILEGvtdidlvvnlKLREEVLVEKClgrricsecgknfnvadidlkgeDGRPGIVMP 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
3ADK_A       129 RLLKRGETSG----RVDDNEETIKKRLETYYKATEPVIAFYEKRG 169
Cdd:PLN02459 183 PLLPPPECASklitRADDTEEVVKARLRVYKEESQPVEDFYRKRG 227
PRK14526 PRK14526
adenylate kinase; Provisional
 10-183 1.52e-26

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 100.70  E-value: 1.52e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        10 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAmVAKVDTSK 89
Cdd:PRK14526   2 KLVFL-GPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDK-INTIKNND 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        90 GFLIDGYPREVKQGEEFERKIGQPTLLLYVdAGPETMTKRLLKR---------------------------GETSGRVDD 142
Cdd:PRK14526  80 NFILDGFPRNINQAKALDKFLPNIKIINFL-IDEELLIKRLSGRrickscnnifniytlptkekgicdvckGDLYQRKDD 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
3ADK_A       143 NEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDDV 183
Cdd:PRK14526 159 KEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEV 199
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 5-170 6.69e-25

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 96.79  E-value: 6.69e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         5 KLKKSKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvAK 84
Cdd:PTZ00088   2 KLKGPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEI-AK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        85 V--DTSKGFLIDGYPREVKQGEEFErKIGQPTLLLYVDAGPETMTKRLLKR----------------------------G 134
Cdd:PTZ00088  81 VtdDCFKGFILDGFPRNLKQCKELG-KITNIDLFVNIYLPRNILIKKLLGRricntcnrnfniahirsdpydmppilppA 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
3ADK_A       135 ETSG---------RVDDNEETIKKRLETYYKATEPVIAFYEKRGI 170
Cdd:PTZ00088 160 DCEGckgnpklqkRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
PRK14529 PRK14529
adenylate kinase; Provisional
 12-183 5.47e-17

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 75.53  E-value: 5.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        12 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMvaKVDTSKGF 91
Cdd:PRK14529   3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETL--KQDGKNGW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        92 LIDGYPREVKQGEEFERKIGQPTLLL-YV--------DAGPETMTKRLLKR------------------------GETSG 138
Cdd:PRK14529  81 LLDGFPRNKVQAEKLWEALQKEGMKLdYVieillpreVAKNRIMGRRLCKNdnnhpnnifidaikpdgdvcrvcgGELST 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
3ADK_A       139 RVDD-NEETIKKRLETYYKATEPVIA---FYE---KRGIVR--KVNAEGSVDDV 183
Cdd:PRK14529 161 RADDqDEEAINKRHDIYYDTETGTLAaayFFKdlaAKGSTKyiELDGEGSIDEI 214
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 12-154 1.43e-08

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 51.54  E-value: 1.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         12 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEImekGQLVPlETVLDMLRDAMVAKVDTskgf 91
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKRLFGEGRPSISYYTDA---TDRTY-ERLHELARIALRAGRPV---- 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
3ADK_A         92 LIDG---YPREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRGETSG-RVDDNEETIKKRLETY 154
Cdd:pfam13671  74 ILDAtnlRRDERARLLALAREYGVPVRIVVFEAPEEVLRERLAARARAGGdPSDVPEEVLDRQKARF 140
TMPK cd01672
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ...
 10-192 5.98e-08

Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).


Pssm-ID: 238835  Cd Length: 200  Bit Score: 50.73  E-value: 5.98e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       10 KIIFVVGGPGSGKGTQCEKIVQ---KYGYTHLSTGDLlraevsSGSARGKMLSEIMEKGQLVPLETVLDML-----RDAM 81
Cdd:cd01672   1 MFIVFEGIDGAGKTTLIELLAErleARGYEVVLTREP------GGTPIGEAIRELLLDPEDEKMDPRAELLlfaadRAQH 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       82 VAKVD---TSKGFLI--D----------GYPR-----EVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRGETSGRVD 141
Cdd:cd01672  75 VEEVIkpaLARGKIVlsDrfvdsslayqGAGRglgeaLIEALNDLATGGLKPDLTILLDIDPEVGLARIEARGRDDRDEQ 154

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
3ADK_A      142 DNEETIKKRLETYYKatepVIAFYEKRGIVrkVNAEGSVDDVFSQVCTHLD 192
Cdd:cd01672 155 EGLEFHERVREGYLE----LAAQEPERIIV--IDASQPLEEVLAEILKAIL 199
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
11-183 5.47e-07

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 47.22  E-value: 5.47e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTgDLLRAEVssgsaRGKMLSEIMEKGQLVPL--ETVLDMLRDAMVAKVDTs 88
Cdd:COG0645   1 LILVCGLPGSGKSTLARALAERLGAVRLRS-DVVRKRL-----FGAGLAPLERSPEATARtyARLLALARELLAAGRSV- 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       89 kgfLIDG---YPREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRGETSGRVDDNEETIKKRLETYykatEPVIAFY 165
Cdd:COG0645  74 ---ILDAtflRRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEARNAEGGDSDATWEVLERQLAFE----EPLTEDE 146

                       170
                ....*....|....*...
3ADK_A      166 EKRGIVRKVNAEGSVDDV 183
Cdd:COG0645 147 GFLLVVDTSGLEEALAAL 164
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-150 2.65e-06

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 45.17  E-value: 2.65e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A       11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEImekgqlvpletvldmlRDAMVAK---VDT 87
Cdd:cd02020   1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEEVGKLASEVAAIPEV----------------RKALDERqreLAK 64

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
3ADK_A       88 SKGFLIDGyprevkqgeefeRKIG-----QPTLLLYVDAGPETMTKR---LLKRGETSGRVDDNEETIKKR 150
Cdd:cd02020  65 KPGIVLEG------------RDIGtvvfpDADLKIFLTASPEVRAKRrakQLQAKGEGVDLEEILAEIIER 123
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
10-150 4.64e-06

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 44.94  E-value: 4.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        10 KIIFVVGGPGSGKGtQCEKIVQKYGYTHLSTGDLLRAEVSSG------SARGKMLSEIMEK-GQLVPLETVLDMLRDAmv 82
Cdd:PRK01184   2 KIIGVVGMPGSGKG-EFSKIAREMGIPVVVMGDVIREEVKKRgleptdENIGKVAIDLRKElGMDAVAKRTVPKIREK-- 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        83 akvdTSKGFLIDGYpREVKQGEEFERKIGQPTLLLYVDAGPETMTKRLLKRgetsGRVDDNE--ETIKKR 150
Cdd:PRK01184  79 ----GDEVVVIDGV-RGDAEVEYFRKEFPEDFILIAIHAPPEVRFERLKKR----GRSDDPKswEELEER 139
PRK04182 PRK04182
cytidylate kinase; Provisional
 11-45 3.52e-04

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 39.79  E-value: 3.52e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
3ADK_A        11 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLR 45
Cdd:PRK04182   2 IITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFR 36
PRK04040 PRK04040
adenylate kinase; Provisional
 8-148 4.15e-04

adenylate kinase; Provisional


Pssm-ID: 235210  Cd Length: 188  Bit Score: 39.49  E-value: 4.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         8 KSKIIFVVGGPGSGKGTQCEKIVQK--YGYTHLSTGDLlraevssgsargkMLSEIMEKGqLV---------PLET---- 72
Cdd:PRK04040   1 MMKVVVVTGVPGVGKTTVLNKALEKlkEDYKIVNFGDV-------------MLEVAKEEG-LVehrdemrklPPEEqkel 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A        73 -------VLDMLRDAMV-----AKVDTSKGFLIdGYPREVKqgeefeRKIgQPTLLLYVDAGPETMTKRLLkRGETSGRV 140
Cdd:PRK04040  67 qreaaerIAEMAGEGPVivdthATIKTPAGYLP-GLPEWVL------EEL-NPDVIVLIEADPDEILMRRL-RDETRRRD 137


                 ....*...
3ADK_A       141 DDNEETIK 148
Cdd:PRK04040 138 VETEEDIE 145
AAA_18 pfam13238
AAA domain;
12-145 1.83e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.02  E-value: 1.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         12 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRDAMVAKVDTSKGF 91
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESKRLDEDKLDRLLDLLEENAALEEGGNLIIDGH 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
3ADK_A         92 LIDGYPREVKQGEEFerkigqptlllYVDAGPETMTKRLLKRGETSGRVDDNEE 145
Cdd:pfam13238  81 LAELEPERAKDLVGI-----------VLRASPEELLERLEKRGYEEAKIKENEE 123
Nitrogenase_VnfN_like cd01971
Nitrogenase_vnfN_like: VnfN subunit of the VnfEN complex-like. This group in addition to VnfN ...
 103-174 3.72e-03

Nitrogenase_vnfN_like: VnfN subunit of the VnfEN complex-like. This group in addition to VnfN contains a subset of the beta subunit of the nitrogenase MoFe protein and NifN-like proteins. The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia. NifEN participates in the synthesis of the iron-molybdenum cofactor (FeMoco) of MoFe protein of the molybdenum(Mo)-nitrogenase. NifB-co (an iron and sulfur containing precursor of the FeMoco) from NifB is transferred to NifEN where it is further processed to FeMoco. VnfEN may similarly be a scaffolding protien for the iron-vanadium cofactor (FeVco) of the vanadium-dependent (V)-nitrogenase. NifE and NifN are essential for the Mo-nitrogenase, VnfE and VnfN are not essential for the V-nitrogenase. NifE and NifN can substitute when the vnfEN genes are inactivated.


Pssm-ID: 238931 [Multi-domain]  Cd Length: 427  Bit Score: 37.39  E-value: 3.72e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
3ADK_A      103 GEEFERKIGQPTLLL-YVDAGPETMTKRLLKRGETSGRVDDNEET-IKKRLETYYKATEPVIAFYEKRGIVRKV 174
Cdd:cd01971 223 AQHLEEKYGQPYIHSpTLPIGAKATAEFLRQVAKFAGIEKAKVEAfIKAEEKRYYHYLERFSDFMARWGLPRRF 296
Thymidylate_kin pfam02223
Thymidylate kinase;
16-187 5.59e-03

Thymidylate kinase;


Pssm-ID: 396690  Cd Length: 184  Bit Score: 36.13  E-value: 5.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         16 GGPGSGKGTQCEKIVQKYGYTHLSTgdLLRAEVSSGSARGKMLSEIMEKGQLVPLETVLDMLRD-----AMVAKVDTSKG 90
Cdd:pfam02223   3 GLDGAGKTTQAELLKERLKEQGIKV--VFTREPGGTPIGEKIRELLLRNEELSPLTEALLFAADriqhlEQKIKPALKQG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3ADK_A         91 FLIDG---------YPREVKQGEEFERKI-----GQPTLLLYVDAGPETMTKRLLKRGEtsgrvddNEETIKKRLETYYK 156
Cdd:pfam02223  81 KTVIVdrylfsgiaYQGAKGGDLDLVLSLnpdvpGKPDLTFLLDVDPEVALKRLRRRGE-------LEKTEFEQLDFLRK 153

                         170       180       190
                  ....*....|....*....|....*....|.
3ADK_A        157 ATEPVIAFYEKRGIVRKVNAEGSVDDVFSQV 187
Cdd:pfam02223 154 VRERYLELAKFDERIKIIDASLSIEEVHEEI 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH